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Objective: To investigate the relationship between serum neurofilament light chain protein (NFL), homocysteine (Hcy), irisin (Irisin) and cognitive function and seizure control after treatment in patients with epilepsy. Methods: 196 patients with epilepsy admitted to The Affiliated Hospital of Xuzhou Medical University from February 2021 to February 2023 were selected,according to the evaluation results of the Montreal Cognitive Assessment Scale (MoCA), patients were divided into cognitive impairment group and non-cognitive impairment group, with 70 cases and 126 cases respectively. All patients with epilepsy were treated with antiepileptic drugs, the levels of serum NFL, Hcy and Irisin were detected before treatment, the seizure control was evaluated 6 months after treatment, the patients were divided into complete control group (139 cases) and incomplete control group (57cases) according to this. The factors affecting the incomplete control of seizures in patients with epilepsy after treatment were analyzed by multivariate Logistic regression analysis. Results: The level of Irisin in cognitive impairment group was lower than that in non-cognitive impairment group, and the levels of serum NFL and Hcy were higher than those in non-cognitive impairment group (P＜0.05). The levels of serum NFL and Hcy in incomplete control group were higher than those in incomplete control group (P＜0.05), and the level of Irisin was lower than that in incomplete control group (P＜0.05). Electroencephalogram abnormalities, generalized seizures, high NFL and Hcy were risk factors for incomplete control after antiepileptic treatment in patients with epilepsy (P＜0.05), and high Irisin was a protective factor (P＜0.05). Conclusion: The levels of serum NFL and Hcy in patients with epilepsy and cognitive impairment are increase, and the level of Irisin is decrease, which are relate to the control of seizures after antiepileptic treatment. [ABSTRACT FROM AUTHOR]

Objective: The predictive value and clinical significance of peripheral blood neutrophil to lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) to serum alpha-fetoprotein (AFP) detected in elderly patients with undifferentiated early gastric cancer were observed. Methods: A total of 80 patients with undifferentiated early gastric cancer, 80 patients with benign gastric diseases, and 80 healthy individuals were included. The above patients were divided into experimental group 1, experimental group 2, and control group. Serum AFP, NLR, and PLR tests were carried out, and the three groups were compared. Serum AFP, NLR, and PLR levels were used to evaluate the predictive effect and significance of serum AFP, NLR, and PLR in elderly patients with undifferentiated early gastric cancer. Results: The expression levels of NLR, PLR and AFP in the observation group 1 and observation group 2 were higher than that in the control group(P＜0.05); The levels of serum NLR, PLR and AFP in patients with lymph node metastasis were higher than those in patients without lymph node metastasis(P＜0.05); The levels of serum NLR, PLR and AFP in patients with T1bN0M0 were higher than those in patients with T1aN0M0(P＜0.05); Taking benign gastric diseases as a control, the diagnostic effects of serum NLR, PLR and AFP in patients with gastric cancer were analyzed under correlation analysis. The areas of serum AFP, NLR and PLR were 0.685, 0.755 and 0.743 respectively, with sensitivity of 65%, 69% and 75% respectively, and specificity of 72%, 74% and 59% respectively. Under the combined detection of serum AFP, NLR and PLR, the sensitivity can reach 72% and the specificity can reach 79%. Compared with a single detection, the combined detection of serum AFP, NLR and PLR has a higher specificity. Conclusion: For the elderly patients with undifferentiated early gastric cancer, the detection of serum AFP, NLR, PLR can evaluate and predict their condition, provide a certain reference basis for clinical practice, and have great clinical promotion and application value. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Objective] The study aimed to investigate the expression and localization of FKBP5 gene and protein in different tissues and different stages of follicular development in Mianalatai sheep. [Method] The full-length CDS region of FKBP5 gene in Altay sheep was amplified by PCR, and a molecular phylogenetic tree was constructed; The expression levels of FKBP5 gene and protein in different organs and tissues such as ovary of Altay sheep were detected by real-time qPCR and Western blot; The expression of FKBP5 gene in follicles of different sizes and corpus luteum of Altay sheep was detected by real-time qPCR; And the expression localization of FKBP5 protein in ovary of Altay sheep was detected by immuno histochemical technique. [Result] The CDS region sequence of FKBP5 gene in Altay sheep was 1390 bp in length and encoded 462 amino acids; sheep was closely related to goats and cattle and distantly related to chickens (birds) ; FKBP5 gene and protein were expressed in sheep heart, liver, spleen, lung, kidney, uterus, ovary, fallopian tube and testis, with the highest expression in the fallopian tube, followed by liver, spleen, uterus, ovary and testis organs and tissues, with lower expression in the heart, lung and kidney; FKBP5 gene expression was the highest in large follicles and extremely significantly higher than that in ovaries, small follicles and corpus luteum (P＜0.01), followed by ovaries and small follicles, with the lowest expression in the corpus luteum; FKBP5 gene expression was slightly different in different cells of large and small follicles.Its expression in large theca cells was significantly higher than that in other types of cells (P＜0.01), while its expression in large theca GCs was also significantly higher than that in small theca GCs, theca cells, and cumulus cells of large and small follicles (P＜0.05) ; FKBP5 protein was expressed in primary follicles, secondary follicles, corpus luteum tissues, and oocytes, cumulus cells, granulosa cells, and theca cells of large and small antral follicles in Altay sheep. [Conclusion] It is speculated that FKBP5 gene may play a role in follicular development in Altay sheep. [ABSTRACT FROM AUTHOR]

Copyright of Automotive Digest is the property of Automotive Digest Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Frozen food has been much more popular in China in recent years. It is also a high requirement for the eating quality with the popularity of frozen food. The size of the internal ice crystal has been the most important factor in the quality. Common freezing includes flat plate freezing, spiral tunnel freezing, and liquid nitrogen spraying. Different freezing can often be chosen, according to the characteristics of the product. The process can convert the free water into ice in food, thus reducing the water activity in the food matrix. The immobilization of free water can inhibit the growth of microorganisms, and then slow down the enzymatic and chemical degradation reactions for less food spoilage. The speed and size of the ice crystals can be critical to the quality of the frozen food. It is preferred that the small-sized ice crystals are normally distributed within the cells in some foods with a cellular structure (such as fruits, vegetables, and meat). As such, the high quality of foods can also be maintained for the least damage to the cellular structure. But, the large ice crystals can result in an icy and sandy taste, which is unacceptable to the consumers. Therefore, it is a common demand from the industry and consumers to reduce the size of ice crystals for the better quality of products. A magnetic field has been an emerging physical way to fully characterize by the strong penetration in the food raw materials. There are some variations in the motion and water distribution state of water molecules in food, thereby accelerating the freezing rate. Therefore, the frozen product quality can be much closer to the fresh state. This study aims to explore the effect of magnetic field-assisted freezing on the quality of frozen cooked noodles. Different magnetic field intensities were selected to assist the frozen noodles: 3, 6, 9, 12, 15, and 18 Gs. The control group (CK) was set as the blank group without the addition of a magnetic field. The results showed that the freezing rate of frozen cooked noodles was significantly (P<0.05) accelerated by 4 min, while the whiteness, hardness, chewiness, shear force, and the content of bound water in the water distribution state significantly (P<0.05) increased by 2.37%, 7.40%, 12.41%, 19.20%, and 10.95%, respectively, whereas, the cooking loss, the content of freezer water, and the aging degree of starch molecules significantly (P<0.05) decreased by 17.88%, 9.44%, and 0.22%, respectively, compared with the CK under the magnetic field intensity of 12 Gs. There were much more uniform and fine ice crystals in the micro-structure in this case. The freezing rate of the noodles was accelerated under the action of the magnetic field. The growth of ice crystals was then inhibited for less mechanical damage to the inside of the frozen cooked noodles. There were also some changes in the movement state of the water molecules in the frozen cooked noodles. The disorder has developed into order, which reduced the energy consumed by the movement of water molecules. The water distribution state also changed to make the internal structure of the frozen cooked noodles more stable with the increase in the bound water. The best freezing performance was also achieved in the magnetic field strength of 12 Gs. The magnetic field can be expected to improve the quality of frozen cooked noodles. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Soil & Water Conservation is the property of Bulletin of Soil & Water Conservation Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Garden Construction & Urban Planning is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Garden Construction & Urban Planning is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of the Chinese Ceramic Society is the property of Bulletin of the Chinese Ceramic Society Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

【Objective】The present paper was conducted to screen differentially expressed miRNA from lambs and adult ewes through modern molecular biology and high-throughput sequencing technology,and further dig out and identify related genes related to follicular development,and reveal signaling pathways and molecular regulatory networks of their differences in traits. 【Method】With lamb and ewe granulosa cells as the research object,the high-throughput sequencing(RNA-Seq) technology for RNA library construction was applied to reveal the genetic differences between the lamb and adult sheep from the transcriptome level,the identification of differentially expressed miRNA,and the differences of expression of MI RNA and its target gene functional annotation and clustering analysis and pathway enrichment etc were studied.【Result】More than 200 miRNAs were identified from two miRNA libraries,and 1/3 of them were identified as new miRNAs. Of the9 differences in the common identification of miRNA,the relative ewes,the lamb had 4 miRNA up-regulated and 5 down-regulation. Among them,the up regulation of oar-miR-106 a was the most significant(1. 85),and the oar-miR-10 a downregulation was the most significant(-2. 20). The GO enrichment and KEGG pathway analysis of all the target genes of all miRNAs in two libraries showed that the abundance of PI3 K/Akt signaling pathway was the highest. Real time fluorescence quantitative PCR confirmed 5 randomly selected miRNA,and the results were consistent with the sequencing data. 【Conclusion】miRNAs may play an important role in the reproductive physiology of sheep after superovulation,including the development of follicle and oocyte and the proliferation of granulosa cells. [ABSTRACT FROM AUTHOR]

【Objective】 Platelet glycoprotein 4(CD36) gene plays a variety of biological functions in model animals, which may play an important role in the development of sheep follicles by transcriptome analysis, and the sequence structure and biological function of TSP-1 gene were studied. 【Method】The full-length TSP-1 gene of Aletai sheep CDS region amplified by PCR software was obtained, the protein sequences and functional region of the CD36 gene were analyzed, and while using the method of fluorescence quantitative PCR, the expression of 5 heads of 1 years of Aletai sheep in 10 organizations were detected. 【Result】The CD36 gene was 1419 bp in length, encoding 472 amino acids, which was in full accord with the predicted sequence. Phylogenetic tree analysis showed that the genetic distance between sheep and cattle was close. CD36 protein is a lipophilic hydrophilic protein with 1 transmembrane helix structure, amino acids in the 1-20 position in the signal peptide, 8 N-glycosylation and 41 potential phosphorylation sites, including 19 Ser, 15 Thr and 7 Tyr. Detection of CD36 gene in different tissues and different diameters of follicles showed that CD36 gene expressed in 7 tissues of sheep, heart and lung and small follicles in the expression of CD36 was significantly different(P < 0.05), and the overall expression level in the different diameters of follicles was low. 【Conclusion】 The results showed that CD36 gene may play an important role in the development of sheep follicles. [ABSTRACT FROM AUTHOR]

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Southern Agriculture is the property of Journal of Southern Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Southern Agriculture is the property of Journal of Southern Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)