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目的建立福建省三明地区妊娠期特异性甲状腺激素参考范围，研究各指标在妊娠期的变化趋势并与国内其他地区水平进行比较。方法收集2023年3月29日至2023年6月28日在三明市第一医院产科就诊且符合研究纳入标准的605名单胎妊娠孕妇的临床资料，并纳入同期229名非妊娠妇女作为对照组。检测研究对象的促甲状腺激素（TSH）、游离甲状腺素（FT4）及游离三碘甲状腺原氨酸（FT3）水平。建立妊娠早、中、晚期甲状腺激素参考范围，以P2.5~P97.5区间表示，对比各指标在妊娠期的变化趋势，并与全国各地区相同类型研究结果进行比较。结果TSH、FT4、FT3在妊娠各期的总体差异具有统计学意义（P均4水平明显降低，妊娠早期FT3水平与非孕期妇女相似。妊娠中期开始，TSH水平升高、FT3及FT4水平逐渐下降。本研究建立的妊娠期甲状腺相关指标参考范围如下：妊娠早期：TSH（0.068，2.943）μU/mL，FT3（4.302，6.888）pmol/L，FT4（8.240，14.719）pmol/L；妊娠中期：TSH（0.419，3.274）μU/mL，FT3（4.074，6.629）pmol/L，FT4（6.726，11.980）pmol/L；妊娠晚期：TSH（0.422，3.570）μU/mL，FT3（3.741，5.850）pmol/L，FT4（6.103，10.347）pmol/L。全国各省市建立的妊娠期甲状腺激素参考范围具有较大差异。结论妊娠妇女甲状腺功能与非妊娠妇女不同，且妊娠各期孕妇TSH、FT3、FT4水平存在显著差异。妊娠期甲状腺激素受到地域、人群、实验室检测方法等多因素的影响。因此，建立三明地区特异性的妊娠期甲状腺激素参考范围有益于本地区妊娠人群甲状腺疾病的诊治。

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Objective To investigate the relationships of expression levels of microRNA-143-3p (miR-143-3p) and timeless circadian regulator (TIMELESS) mRNA in epithelial ovarian cancer (EOC) tissues with the clinicopathological characteristics and prognosis of patients. Methods We selected 106 patients with EOC, and the EOC tissues and corresponding adjacent tissues were collected. Real-time fluorescence quantitative PCR was performed to detect miR-143-3p and TIMELESS mRNA expression. The binding sites of miR-143-3p and TIMELESS were predicted by online databases such as TargetScan, StarBase, and miRWalk. Pearson correlation was used to analyze the correlation between miR-143-3p and TIMELESS mRNA. We analyzed the relationships between the expression of miR-143-3p and TIMELESS mRNA and the clinicopathological characteristics of EOC patients. EOC patients were followed up for three years, and we calculated the cumulative survival rate. EOC patients were divided into high/low miR-143-3p and TIMELESS mRNA expression groups according to the mean value of their expression, and Kaplan-Meier method was used to draw survival curves for survival analysis. Multivariate Cox regression analysis was performed to analyze the effects of miR-143-3p and TIMELESS on the prognosis of EOC patients. Results Compared with the adjacent tissues, miR-143-3p was low expressed and TIMELESS mRNA was highly expressed in EOC tissues (both P<0. 05) The miR-143-3p and TIMELESS had a binding site at 3′-untranslated region 1453-1460. The miR-143-3p and TIMELESS mRNA expression in EOC tissues showed a negatively correlated (r=–0. 748，P<0. 05). The miR-143-3p and TIMELESS mRNA expression was related to International Federation of Gynecology and Obstetrics (FIGO) stage, degree of differentiation, lymph node metastasis, and distant metastasis (all P<0. 05). The 3-year overall survival rate of 106 EOC patients was 69. 81% (74/106). The high miR-143-3p expression patients had a higher 3-year overall survival rate than the low miR-143-3p expression patients, and the 3-year overall survival rate of patients with high TIMELESS mRNA expression was lower than that of patient with low TIMELESS mRNA expression patients (both P<0. 05). Independent risk factors for death in EOC patients were FIGO stage Ⅲ-Ⅳ, poor differentiation, lymph node metastasis, distant metastasis, and TIMELESS mRNA ≥ 1. 11, and the independent protective factor was miR-143-3p ≥ 0. 97（all P<0. 05). Conclusion In EOC tissues, miR-143-3p was low expressed and TIMELESS mRNA was highly expressed, and their expression changes were closely associated with FIGO stage, degree of differentiation, lymph node metastasis, distant metastasis and prognosis. [ABSTRACT FROM AUTHOR]

This paper analyzed the mental status and health needs of young patients with advance cancer. A brief summary of strategies about psychological support, death education, symptomatic treatment and end-of-life care was provided, in order to provide the quality of palliative care for young patients with advance cancer. (本文分析晚期癌症患者的特殊心理及需求, 通过提供对年轻晚期癌症临终患者及照护者心理支持、死亡教育、对症治疗和生活照护等手段, 提高年轻晚期癌症患者临终阶段的生存质量。)

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Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Objective To explore the effectiveness and safety of silver ion dressings in treating deep second-degree burns and scalds. Methods From October 2019 to June 2020, Department of Burn and Plastic Surgery, the Second Nanning People's Hospital treated 132 patients with deep second degree burn and scald wounds. Divided into a treatment group (65 cases) and a control group (67 cases), the treatment group was treated with silver ion dressing, while the control group was treated with silver containing dressing Atrauman Ag. Compare the total effective rate, wound healing rate, wound healing time, and negative rate of bacterial culture of wound secretions between the two groups of patients, and detect the patient's vital signs before and after treatment, laboratory examinations, electrocardiogram, comprehensive evaluation, and silver content in blood and urine, etc. Record serious adverse reactions events during treatment. Results Based on the full analysis set (FAS) and per protocol set (PPS), the results show that the total effective rate of the treatment group is not inferior to that of the control group (P<0.05). There was no statistical difference in wound healing rate and wound healing time between the treatment group and the control group (P>0.05). There was no significant difference in the rate of bacterial culture of wound secretions turning negative between the two groups before and after treatment (P>0.05). There was no significant difference in the subjects' vital signs, laboratory examinations, electrocardiogram, comprehensive evaluation, and blood silver, urine silver concentration between the treatment group and the control group before and after treatment (P>0.05). There were no serious adverse reactions events in the experimental group and the control group. Conclusion The effectiveness of silver ion dressing is not inferior to silver dressing Atrauman Ag. During the treatment, no serious adverse reactions events occurred in the two groups. Therefore, the silver ion antibacterial functional dressing is a safe and effective dressing for deep second-degree burns and scalds. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shenzhen University Humanities & Social Sciences is the property of Journal of Shenzhen University (Humanities & Social Sciences) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Michelia gioii is a precious broad-leaved tree species in China, which is of great value in terms of wood, fragrance and landscape. In order to further cultivate excellent seedlings and develop and utilize the non-woody resources, the seedlings of M. gioii were placed under eight light conditions with the same light intensity, which were composed by two photoperiods(12, 16 h·d-1)and four light qualities(R : B=8 : 1, R : B=6 : 1, R : B : P : G=8 : 1 : 1 : 1, R : B : P : G=6 : 1 : 1 : 1, R, B, P and G respectively represent red light, blue light, purple light and green light). The results were as follows : (1)The growth of seedling height and ground diameter, leaf aspect ratio, maximum net photosynthetic rate, dark respiration rate and light compensation point reached the maximum values under the light quality R : B=6 : 1 with a photoperiod of 12 h·d-1, while the leaf area and chlorophyll content were the highest under the light quality R : B : P : G=6 : 1 : 1 : 1 with a photoperiod of 16 h·d-1.(2) Compared to the treatment of photoperiod 12 h·d-1, the indicators in growth of seedling height, leaf area, quality index, chlorophyll a+b content, chlorophyll a/b ratio, carotenoid content and light saturation point showed higher under photoperiod 16 h·d-1. (3) The addition of purple and green light into the red-blue light combination increased the quality index of seedlings and positively affected the synthesis and accumulation of photosynthetic pigments. (4) Compared with the light quality R : B=8 : 1, R : B=6 : 1 had more potential to promote the growth of seedling height, ground diameter and leaf, and to improve the photosynthesis of M. gioii seedlings. In conclusion, the light quality R : B : P : G=6 : 1 : 1 : 1 with a photoperiod of 16 h·d-1 demonstrates the higher possibility to promote the growth and photosynthesis of M. gioii seedlings, followed by the light quality R : B=6 : 1 with a photoperiod of 12 h·d-1. [ABSTRACT FROM AUTHOR]

Vitamin D (VD) is one of the essential nutrients in pregnancy and perinatal period. It is not only related to bone metabolism, but also has multiple neural activities affecting neuroimmune regulation, neurotrophic factors and neurotransmission in the brain. Recent studies have found that VD has varying degrees of influence on the occurrence of depression. Prenatal and postnatal depression as a branch of depression, their relationship with VD is also being studied. VD deficiency can not only lead to recurrent spontaneous abortion, gestational diabetes and pre-eclampsia, but also be associated with depression symptoms during pregnancy and postpartum. It has been reported that VD deficiency may be one of the important risk factors for perinatal depression. Reasonable perinatal VD supplementation has a certain prevention and treatment effect on depression, but more studies are needed to confirm the timing and dose of VD supplementation. Combined with the domestic and foreign literatures published in recent years, we reviewed the correlation between VD deficiency and perinatal depression in this article, providing theoretical basis for early prevention, early diagnosis and timely treatment of the disease, and providing new ideas for later research. [ABSTRACT FROM AUTHOR]

With the rapid development of modern detection technology and scientific research, the chemical structures and functions of isomers are constantly being revealed. The isomer molecules may have completely different biochemical activities, and a certain molecule of the isomer may play an important role in disease pathogenesis or disease treatment, while the other is the opposite. Therefore, the separation and identification of isomers and the exploration of their structures are helpful to furtherly understand the operating mechanism of life, and become one of the research hotspots in the field of analytical chemistry and life sciences. Ion mobility spectrometry (IMS), which has developed rapidly in recent years, is an instrument technology that can analyze the spatial structure of molecules. It can distinguish the isomerism of a certain molecule by measuring the difference in the collision cross-section between different molecular ions and airflow in the gas phase. IMS coupled with mass spectrometry (IMS-MS) is a powerful separation and analysis technology that adds a mobility separation dimension for MS to improve ion structure separation and determination, while also enhances ion mass selection in mobility technology and makes the separation of the analyte have high selectivity. IMS-MS technology has been highly concerned and widely used in the fields of small molecule/metabolite identification, proteomics research, host-guest complexes, and molecular structure identification. This paper was focused on the working principle of different types of IMS, the latest application in different types of isomers and the prospect of IMS-MS. [ABSTRACT FROM AUTHOR]

Objective: To compare the psychotic-like experiences of different roles in school bullying of junior school students. Methods: Totally 4360 junior school students were randomly selected from eight middle schools in Hunan Province. They were assessed with the Chinese version of Olweus Bully/Victim Questionnaire and Community Assessment of Psychic Experience-Positive Subscale (8 items) (CAPE-P8) for evaluating the role of school bullying and psychotic-like experiences. Results: Among the respondents, 81 (1. 9%) were pure bullies, 647 (14. 8%) were pure victims, 196 (4. 5%) were bully-victims and 3436 (78. 8%) were uninvolved. The positive rate of psychotic-like experiences was 64. 3% (2803/4360) . Multivariate logistic regression analysis showed that the risk of psychotic-like experiences was higher in bully-victims (OR=3. 46, 95% Cl:2. 33-5. 12), pure bullies (OR=3. 23, 95% Cl:1. 82-5. 74) and pure victims (OR=2. 79, 95% Cl:2. 26-3. 44) than in those not involved. Conclusion: Junior school students have different psychotic-like experiences of different roles in school bullying, and the risk of detecting psychotic-like experiences is higher in bully-victims. [ABSTRACT FROM AUTHOR]

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Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Materials Science & Engineering (1673-2812) is the property of Journal of Materials Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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