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针对目前串行量子随机数发生器方案中,量子模式提取的信号带宽与数据处理速率之间的权衡在实时产生速率方面造成了瓶颈,文章利用现场可编程门阵列（FPGA）对多个量子边带模式的并行托普利茨（Toeplitz）哈希实时后处理,研究分析了不同规模Toeplitz矩阵的逻辑资源占用,设计了两层并行流水线算法并进行了仿真验证,充分利用FPGA的并行处理优势和硬件资源,最终实现了实时速率8.24 Gbit/s的量子随机数安全后处理。仿真结果表明,量子随机数发生器的熵源具有较好的随机性,经后处理后的随机数自相关系数保持在10-4量级且能通过Diehard测试。通过与集成电路匹配并行提取多个量子边带模式,实现了一种可商业化的高鲁棒性、高速实时量子随机数发生器。

针对当前量子随机数产生技术无法满足通信领域中安全性和高速率的问题,文章提出了一种基于测量光场真空起伏产生量子真随机数的实验方案。与以往报道的实验方案所不同,文章理论分析,量子随机数生成系统中量子正交分量测量中本底光增益对原始随机数中相对量子熵含量的影响,在经典噪声完全被窃听方控制的最差情况假定下,采用量子条件最小熵量化评估原始随机数的随机性。基于理论分析实验中通过相对增强本底光强的同时控制电子学增益,经典电子噪声独立地放大真空噪声分量起伏,提高了系统中量子噪声引入的最小熵含量,同时,基于真空量子噪声是宽带高斯白噪声,有效提升频带提取带宽,提高量子熵源的利用率,在提高量子随机数生成系统安全性的同时提高了量子随机数的产生速率。实验结果表明,基于安全性信息论可证明的托普利茨-哈希（Toeplitz-hash）提取器,实现了6.7 Gbit/s的量子随机数产生,同时利用Nist、Diehard和TestU01-SmallCrush 3种随机数标准测试验证了该方案下生成的量子随机数的真随机性,为真空量子随机数发生器产生速率的提高提供了新的途径。

膜结构是一种柔性结构,膜面容易发生雨水积留。针对ETFE（四氟乙烯）薄膜结构,利用ANSYS软件通过迭代计算分析了正方形平面膜面和正方形气枕膜面的积水极限承载力,考察不同跨度及矢跨比时的积水进展情况。计算结果显示,厚度为250μm的单层正方形平面膜面,跨度3m时就会发生积水破坏。对于气枕膜面,是否发生积水破坏由跨度与矢跨比决定。由两层厚度为250μm的ETFE薄膜叠合的正方形边界气枕膜面,当跨度达到5m时将发生积水破坏,跨度为4m、矢跨比达到1/8及以上时也将发生积水破坏。设计制作了3种矢跨比的ETFE薄膜气枕膜面,进行了积水承载试验,将试验结果与数值分析结果进行了对比。

【目的】研究thapsigargin（TG）对体外培养的人品状体上皮细胞系SRA01／04增殖的影响，并探讨其分子机制。【方法】不同浓度TG处理SRA01／04细胞72h，噻唑蓝比色法（MTT）检测细胞增殖；流式细胞仪（PI法）检测细胞周期改变；透射电镜观察细胞超微结构变化；TUNEL法检测细胞核中DNA的断裂情况；激光共焦显微镜和流式细胞仪检测Caspase3活性亚单位（17／19ku）的表达及阳性细胞表达率。【结果】MTT法测得TG为0．325～5μmol／L时，细胞增殖抑制率变化显著，IC50大约为0．8μmol／L；透射电镜显示TG处理SRA01／04细胞膜皱缩，染色体浓缩、边集、核膜裂解、凋亡小体形成；流式细胞仪（PI法）及TUNEL法检测TG浓度为0，0．1，0．5，1，10μmol／L分别处理SRA01／04细胞72h，细胞凋亡率随浓度的增加而增加，呈浓度依赖性；TG处理后细胞Caspase3阳性表达率也呈浓度依赖性增加，TG为10μmol／L时，几乎每个细胞浆内Caspase3都被激活。【结论】Thapsigargin可能通过激活Caspase3为诱导体外培养的人晶状体上皮细胞系SRA01／04细胞凋亡而抑制其增殖，TG为预防后发性白内障的药物研究提供了基础。

【目的】探讨蛋白酶体筇亚单位（PSMB5）基因过表达对氧化条件下晶状体上皮细胞的影响。【方法】构建重组质粒pcDNA3．1-PSMB5并将其转染人人晶状体上皮细胞株SRAO1／04中，形成稳定表达，同时设pcDNA3．1空载体为对照组。RT—PCR法及Western blot法分别检测PSMB5基因及蛋白的表达情况。H2O2分别作用PSMB5转染细胞及空载体转染细胞，MTT法检测细胞增殖能力的变化。【结果】转染后用G418筛选3周后，获得PSMB5转染及空载体转染的G418抗性的细胞克隆。转染PSMB5基因的细胞PSMB5 mRNA表达强度明显增高．而空载体转染细胞与未转染细胞无显著差异：转染PSMB5基因的细胞的PSMB5蛋白表达也显著高于空载体转染细胞。低浓度H2O2作用后，转染PSMB5基因的细胞增殖能力高于空载体转染细胞。【结论】低浓度氧化环境下蛋白酶体历亚单位PSMB5过表达能对人晶状体上皮细胞具有保护作用。

【目的】比较不同区域猪晶状体上皮细胞的基因表达在转录组水平上的差异。【方法】解剖显微镜下分离晶状体前囊膜, 将附着于其上的上皮细胞分为中央( 直径为 10.56 mm) 和周边两部分。分别提取两个样本的总 RNAs 并经 PCR 扩增, 以 Cy3 和 Cy5 分别标记扩增的中央与周边部分的 cDNA, 与含 7548 个基因的表达谱芯片杂交, 经图像分析, 生物信息学处理获得基因表达在转录水平差异的相关信息。【结果】中央与周边区域的猪晶状体上皮细胞在转录组水平共鉴定出952个有效表达的基因点, 其中差异表达基因 261 个, 以中央区域为参照, 周边上皮细胞 mRNA 上调 137 个, 下调 124 个。差异表达基因主要涉及的功能有: 细胞周期与凋亡、细胞骨架蛋白及细胞外基质、转录、细胞信号分子等。【结论】中央与周边区域猪晶状体上皮细胞基因表达在转录组水平上差异明显。这类差异呈明显的功能聚类。

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In order to study the effect of overlying water conditions on sediment nitrogen in Poyang Lake, the estuarine sediments of Poyang Lake were used as experimental materials. By changing the temperature, pH and disturbance conditions of overlying water, the release characteristics of different forms of nitrogen in sediments were studied. The correlation of nitrogen release in sediments under different environmental conditions was fitted with the functions of first order, second order and third order. The results showed that with the increase of temperature, the release of total nitrogen, ammonia nitrogen and nitrate nitrogen increased significantly. Under acidic condition, the release intensity of ammonia nitrogen was the highest, while under alkaline condition, it was the lowest. The release intensity of total nitrogen and nitrate nitrogen was the highest under alkaline condition. Under different disturbance intensities, the release intensity of ammonia nitrogen, total nitrogen and nitrate nitrogen reached the maximum at 160 r/min. Curve fitting results showed that the release intensity of total nitrogen, ammonia nitrogen and nitrate nitrogen was a function of pH, temperature and disturbance intensity. [ABSTRACT FROM AUTHOR]

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本研究以教育工作者與低社經處境中邊緣青少年的相遇為題，分析不易察覺的先天條件、互動方式及教育關係。本案例研究將分析互動雙方如何陷入常見的「陷阱」，更共構出耐人尋味的「竊案」。最後，針對如何讓社會正義落實於偏鄉教育的課題，提出本研究對教育工作者的啟發。本研究運用多元且跨學科的研究成果，並以「舞臺／表演隱喻」分析師生互動中的文化腳本。結論指出，為更能理解行為偏差青少年的行為與需求，教師需懸置已知、轉換為一種陌生人之眼，更敏銳覺察日常互動中師生共構的現象，發揮師者在教育現場的正面效應。 This study explored educators’ encounters with marginalized students from disadvantaged socioeconomic backgrounds, in order to examine intangible predetermined factors, interactions and teacher-student relationships. Using a case study, it looked into how the two parties may fall into common “traps” that lead to a case of “theft” that may not be as it seems. Finally, some findings from the paper are offered that may serve as inspiration for working teachers on how to achieve social justice in the realm of rural education. We apply multiple and trans-disciplinary research results and use a “stage/performance metaphor” to analyze the cultural scripts hidden in the dynamics of teacher-student interactions. The paper concludes that educators have to suspend the known, and switch to a kind of stranger’s eyes, so that they may become more keenly aware of the co-construction processes with students, and effect a positive influence in pedagogical situations.

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