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摘要：【目的】探索芬太尼诱导的急性痛觉过敏模型中，大鼠脊髓促炎因子表达的变化。【方法】64只雄性SD大鼠分 为2组（n = 32），实验组（Fentanyl组）皮下注射芬太尼60 μg/Kg共4次，每次间隔15 min，对照组（Normal saline组）皮下注射 生理盐水4 次。于注射前1 d（D-1）、注射后1、2、3、4 h 及1 ~ 5 d 对各组大鼠进行压尾机械伤害阈值（Tail flick threshold， TFT）和足底热伤害潜时（Paw withdrawal latency，PWL）两项疼痛行为学测试。注射前1 d，注射后4 h及1 ~ 4 d每组随机选 取4只大鼠处死，取腰段脊髓，以蛋白印迹法（Western blot）测定NF-κB表达，以酶联免疫吸附法（ELISA）测定PGE2、TNF-α、 IL-1β和IL-6的表达。【结果】①对照组大鼠行为学（TFT和PWL）及脊髓NF-κBp65、PGE2、IL-1β，TNF-α分子水平与基础 值相比无统计学差异。②实验组大鼠注射后1hTFT及PWL值升高至最高水平（高于基础水平），随后下降，在注射后第1天 降低至最低水平（低于基础水平），随后上升，在第3 天恢复至基础水平；脊髓NF-κB、PGE2、IL-1β，TNF-α在注射后4 h、 1 及2 d表达升高，IL-6在注射后4 h及1 d表达升高。【结论】急性皮下注射芬太尼可引起大鼠的热及机械痛觉过敏和脊髓 促炎症因子的升高，且行为学及分子学的改变在时间上平行，提示芬太尼诱导的大鼠痛觉过敏和脊髓炎性反应相关。

英国应力蒙皮设计规范BS5950-9对屋面和墙面维护结构所用压型钢板的应力蒙皮作用包括设计与施工作了详细的规定。本文介绍了该规范主要内容的第一部分。

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of South China University of Technology (Natural Science Edition) is the property of South China University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Lack of funding is one of the most important challenges in the achievement of the 2030 Sustainable Development Goals ( SDGs) in African countries. Can foreign direct investment ( FDI) from China as an important source of external financing help African countries achieve the SDGs? This paper used the panel data random effects model to analyze the influence of China's direct investment on SDG scores and then conducted the ordered probit model to examine the influence of FDI from China on the trend of achieving each SDG in Africa, with the SDGs being grouped into social, economic and environmental dimensions . The results showed that China' s direct investment contributed to the achievement of SDGs in Africa. It positively influenced the SDG score in general and some of the 17 SDG scores including SDG7 (affordable and clean energy), SDG8 ( decent work and economic growth), SDG9 ( industry, innovation and infrastructure), SDG12 ( responsible consumption and production), SDG13 ( climate action), and SDG15 ( life on land) . The relationship between FDI from China and the trends for SDG7, SDG8, SDG9, SDGl l (sustainable cities and communities), and SDG 14 ( life below water) was significantly positive. However, the SDG scores above belonged to the economic and environmental dimensions, while FDI from China had no significant influence on the social-dimension SDG scores and trends. To further expand the scale of China' s direct investment, it is suggested that more investment scopes, especially those in the social dimension, should be developed, and China-Africa cooperation should be deepened to crea te a good investment environment for the achievement of African countries' SDGs and to facilitate China' s implementation of promoting the development of developing countries as mentioned in the 2030 Agenda of Sustainable Development and building the China-Africa community with a shared future. [ABSTRACT FROM AUTHOR]

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Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Taiwanese Journal of Agricultural Chemistry & Food Science is the property of Agricultural Chemical Society of Taiwan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to avoid the structural damage of automobile seat and improve the reliability of seat, the method of replacing the side plate material with better yield limit was proposed to improve the safety of seats. The geometry modeling of the main driving seat of a two-compart-ment oar was made with CATIA software,and the finite element model was set up with HYPERMESH software. The validity of the finite element model was validated by comparing the results of downward-pressure stiffness test and simulation analysis. The static strength of seat assembly, backrest and headrest structure were performed through simulation based on GB15083 and GB11550, and the fatigue strength of the seat skeleton assembly was simulated based on QG/T 740. The results indicate that the maximum stress of side plate of seat skeleton exceeds the yield limit of material,the maximum deformation position of seat assembly and backrest meets the requirements of regulations, the fatigue life of seat structure meets the requirements, and the reliability durability meets the design requirements. [ABSTRACT FROM AUTHOR]

Copyright of West China Journal of Stomatology is the property of Sichuan University, West China College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

新型冠状病毒肺炎疫情发生后经1 个多月的抗疫工作，广东凇室布将广东雀新型冠状病毒肺炎疫情防控应急响 应级别由重大突发公共卫生事件一级响应调整为二级响应；然而， 广东重大突发公共卫生事件一级响应调整为二级响应不代表拐 占、的到来，疫情防控形势依然严峻，且由于口腔诊疗专业的特殊性，疫情防控形势更为严峻。该叉根据国家卫生健康委员会颁发 的相关规范标准，以及广东泊、广州市卫生健康委员会的相关诊疗叉件和医院的相关工作指南，为口腔儿童临床诊疗工作开诊前 的筹备提供相关的指引和建议。 [ABSTRACT FROM AUTHOR]

ObjectiveTo investigate the value of serum adenosine deaminase (ADA) in the diagnosis of marked liver fibrosis in patients with chronic hepatitis B virus (HBV) infection. MethodsA total of 493 patients with chronic HBV infection who underwent liver biopsy in Ningbo No. 2 Hospital from May 2011 to October 2016 were enrolled, and according to the degree of liver fibrosis, these patients were divided into S0 group with 79 patients, S1 group with 254 patients, S2 group with 103 patients, S3 group with 35 patients, and S4 group with 22 patients. Biochemical parameters including total bilirubin (TBil), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), albumin (Alb), and ADA were measured, routine blood test was performed, and aspartate aminotransferase-to-platelet ratio index (APRI) was calculated. These indices were compared between groups. An analysis of variance was used for comparison of normally distributed continuous data between multiple groups, and the Kruskal-Wallis H test was used for comparison of continuous data with skewed distribution between groups. The chi-square test was used for comparison of categorical data between groups. A dichotomous logistic regression analysis was performed for these indices, and the receiver operating characteristic (ROC) curve was used to analyze the value of ADA, APRI, or a combination of various indices in the diagnosis of marked liver fibrosis. ResultsThere were significant differences in age, sex, TBil, ALT, AST, alkaline phosphatase, GGT, Alb, ADA, and APRI between the S0, S1, S2, S3, and S4 groups (F=11.41, χ2=14.45, 15.08, 28.27, 48.22, 48.65, 80.53, 17.03, 57.89, and 73.20, all P<0.05). Sex, age, and serum ADA were independent risk factors for marked liver fibrosis (odds ratio = 2.59, 1.05, and 1.12, all P<0.01). ADA, APRI, or a combination of various indices had a certain value in the diagnosis of marked liver fibrosis (all P<0.01), with an area under the ROC curve of 0.70, 0.73, and 0.75, respectively. ConclusionSerum ADA has a certain value in the diagnosis of marked liver fibrosis in patients with chronic HBV infection. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Heilongjiang University of Science & Technology is the property of Journal of Heilongjiang University of Science & Technology Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To study the clinical effect of budesonide inhalation on the children with bronchiolitis and its effect on the serumInterleukin -4 (IL-4) and interferon gamma (IFN- gamma), tumor necrosis factor alpha (TNF- alpha) and T lymphocyte subsets. Methods: 70 patients with bronchiolitis treated in our hospital from January 2014 to January 2017 were selected and divided into the control group and observation group by random number method. In the control group, patients were given oxygen, controlled wheezing and anti-pathogens and other conventional treatment, on this basis, the observation group were treated with nebulized budesonide combined with terbutaline and ipratropium bromide. Results: The total effective rate of treatment was compared between the two groups of patients. The remission time of symptoms and signs and hospitalization time were compared. The levels of serum inflammatory factors and T lymphocyte subsets were also compared before and after treatment. The total effective rate (97.14%) was significantly higher in the observation group than that of the control group (71.43%)(P=0.00); the remission duration of anhelation, the disappearance time of wheezing, rale, moist rale, cough, normal time of heart rate, hospitalization time of observation group were dominantly shorter than those of the control group (P<0.01). After treatment, the ratio of CD3+, CD4+, CD4+/CD8+ cells in the observation group were significantly lower than those of the control group, CD8+ was significantly lower than that of the control group (P<0.01). The level of serum IL-4 and TNF-α in both groups were significantly lower than those of the control group, and the level of serum IFN-γ was significantly higher than that of the control group (P <0.05). Conclusion: Inhalation of budesonide was effective in the treatment of bronchiolitis, it effectively inhibit the inflammation, enhance the immune function, lower the adverse reactions with high safety. [ABSTRACT FROM AUTHOR]

Copyright of Computer Engineering & Science / Jisuanji Gongcheng yu Kexue is the property of Computer Engineering & Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)