A synergy model of the aquaponic system was integrated with soil-based cultivation, particularly for the recycling use of aquaculture wastewater and solids. A three-way water cycle process was also designed in this study. A pilot system was built at Yaomo village, Ningxia Hui Autonomous Region, China in 2020. Three parts were composed mainly of the recirculating aquaculture system (RAS), hydroponics, and soil-based cultivation unit, specifically including the fish tank, radial-flow clarifier, micro-screen drum filter, moving bed biofilm reactor (MBBR), mineralization tank, ultraviolet sterilizer, sump tank, hydroponic troughs, and farmland. In a three-way water cycle process, the first way was a circulation loop of the RAS unit, where the effluent first went through the physical filters under gravity, and then lifted into the MBBR by pump to remove ammonia nitrogen, and nitrate. Finally, the water flowed into the ultraviolet sterilization, and then returned to a fish tank. The second way was a circulation loop of “aquaculture unit to hydroponics unit”, where the aquaculture effluent was loaded with the nutrients, filtered into the hydroponic troughs where the plant roots were fertilized, then recycled back to the fish tank, and remediated cumulated nutrients. The third way was the “aquaculture unit to soil-based cultivation unit” cycle, where the fish sludge solids were accumulated into the mineralization tank, and then irrigated to the farmland after being mineralized by the pump. In the RAS unit, the respiration and metabolism of fish and the decomposition of the residual feed produced ammonia nitrogen and then converted to nitrate nitrogen under the effect of microorganisms in the MBBR and on the surface of plant roots. In the hydroponics unit, the plants absorbed nitrate nitrogen produced from the RAS unit, and then purified the aquaculture wastewater. In the soil-based cultivation unit, the fish sludge solids (mainly composed of degradable organic matter) were degraded to small molecules in a mineralisation tank, whereas, the macronutrients (i.e. N, P, and K) and micronutrients (i.e. Fe, Mn, and Zn) that were bound to the organic molecules were released into the water in their ionic forms to complete the process of nutrient mineralization. The key parameters (including the biomass ratio of fish and vegetables) were calculated to propose the capacity of the mineralization device. According to the calculation, the system was designed to farm 1 400 kg fish in a tank of 28.3 m³, to plant 3 648 vegetables in 96 circular pipes each of 8 m, and the mineralization tank volume was set to 2 m³ . Taking the largemouth bass as the case, the lettuce and tomato as the culturing object for 160 days from May 21st to October 28th. The experiment results showed that better growth of fish was achieved, where the final culture density reached up to 41.6 kg/m³, the specific growth rate was 0.42%, the survival rate was 99.95%, and the feed coefficient was 1.4. The better growth of vegetables was also obtained, where 1205 kg of hydroponic lettuce and 2 400 kg of tomato were harvested during the period. Consequently, the water quality was stable: the average concentration of total ammonia nitrogen (TAN) was (0.83±1.46) mg/L, the average concentration of nitrite (NO2 - -N) was (0.035±0.062) mg/L, the average concentration of nitrate (NO3 - -N) was (25.1±8.06) mg/L, the concentration range of dissolved oxygen was 4.25-7.16 mg/L, and the average pH was 6.8. More importantly, the average concentration of total phosphorus and potassium in water increased by 141% and 7%, respectively, during the mineralization process. The excellent economic and ecological benefits of the system were obtained: the annual profit was about 46 000 Yuan, the use of chemical fertilizers was reduced by 4/5, the use of pesticides was reduced by 3/4, and the daily water exchange was less than 5%. [ABSTRACT FROM AUTHOR]