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Objective To investigate the effect and safety of auricular acupoint pressing therapy at different frequencies on insomnia and constipation. Methods Patients with insomnia and constipation who were hospitalized in the hospital from January 2023 to June 2024 were selected as the research objects. According to the random number table method, the patients were divided into the control group (continuous treatment of auricular acupointy pressing) (n=100), the observation group A (continuous treatment with auricular bean-pressing for 5 days, stopped for 2 days) (n=100), and the observation group B (continuous treatment with auricular acupoint pressing for 3 days, stopped for 1 day) (n=100). The patients with insomnia and constipation were intervened for 14 days, and the effect and safety of treatment were observed. Results After treatment, the total effective rate of treatment on insomnia and constipation in observation group A and observation group B was higher than that in control group (P < 0. 05). The Pittsburgh Sleep Quality Index (PSQI) score and Constipation scoring system (CSS) points of the three groups were improved compared with those before treatment (P < 0. 05). fter 14 days of treatment, the PSQI score and CSS scores of the observation group A and the observation group B were lower than those of the control group (P < 0. 05), and PSQI score and CSS scores in the observation group A were lower than those in the observation group B (P < 0. 05). The incidence of adhesive patch shedding and displacement in the observation group A and the observation group B were lower than those in the control group (P < 0. 05), and the incidence of adhesive patch falling off and displacement in the observation group A was lower than that in the observation group B (P < 0. 05). Conclusion The treatment frequency of auricular acupoint pressing for 5 consecutive days and stopped for 2 days is better in improving the symptoms of patients with insomnia and constipation, and reducing the risk of adhesive plaster falling off and displacement. (目的 探讨不同治疗频次耳穴压豆干预失眠和便秘的效果及安全性。方法 选取2023年1月—2024年6月医院住院治疗的失眠和便秘的患者为研究对象。应用随机数字表法将患者分为对照组(耳穴压豆每日连续治疗)(n=100)、观察A组(耳穴压豆连续治疗5 d, 暂停2 d)(n=100)、观察B组(耳穴压豆连续治疗3 d, 暂停1 d)(n=100)。三组耳穴压豆治疗方法相同, 但治疗频次不同。对失眠、便秘的患者进行干预14天, 观察治疗效果及安全性。结果 治疗后观察A组、观察B组失眠、便秘临床总有效率均高于对照组, 差异有统计学意义(P＜0. 05)。治疗后匹兹堡睡眠质量指数(PSQI)评分、慢性便秘严重度(CSS)评分三组较治疗前改善(P＜0. 05)。治疗14 d时观察A组、观察B组PSQI评分、CSS评分降低较对照组更明显(P＜0. 05), 且观察A组PSQI评分、CSS评分改善优于观察B组(P＜0. 05)。试验过程中观察A组及观察B组的胶贴脱落、移位发生率低于对照组(P＜0. 05), 观察A组胶贴脱落、移位发生率较观察B组低(P＜0. 05)。结论 采用耳穴压豆连续治疗5 d、暂停2 d的治疗频次, 对失眠、便秘患者症状改善效果更佳, 能够减少胶贴脱落、移位等情况发生。)

Copyright of Journal of Xi'an Jiaotong University is the property of Editorial Office of Journal of Xi'an Jiaotong University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

It is very important to guarantee the supply of medicine under major public health crisis. Implementing compulsory licensing for pharmaceutical patents is an effective means to ensure the adequate supply of special patented medicines. To ensure the accuracy and effectiveness of the system implementation, the principle of subjectivity, the principle of public welfare and the principle of balance should be followed, and the classification framework of general compulsory license, special compulsory license and export compulsory license should be established. In the specific design of the system, the subject of application and the subject of initiation for compulsory license of pharmaceutical patent should be limited to any unit or individual. Additionally, the initiation cause, the initiation procedure and compensation standards should be further clarified, to ensure the effective implementation of the system under major public health crises. [ABSTRACT FROM AUTHOR]

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South China University of Technology (Natural Science Edition) is the property of South China University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of the Chinese Ceramic Society is the property of Bulletin of the Chinese Ceramic Society Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shenzhen University Science & Engineering is the property of Editorial Department of Journal of Shenzhen University Science & Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Farming practices can contribute to the soil organic carbon storage in the carbon budget of farmland ecosystems. This study aims to determine the dynamic response pattern of conservation tillage to the soil organic carbon. The density of soil organic carbon under conservation tillage was collected from the cornfield in Jilin Province, China from 2000 to 2020 at the county and grid scales. The "golden corn belt" in Jilin Province was taken as the study area, and the spring corn was selected as the research object. Remote sensing inversion was used to couple the Denitrification-Decomposition (DNDC) model. Firstly, the crop residue coverage was inverted using remote sensing. The input parameter of the model was selected to optimize the residue management module in the DNDC model. Secondly, the local soil properties were combined with the meteorology and farmland measure data. Regional simulation was implemented using two division units, in order to accurately depict the spatiotemporal dynamic evolution of soil organic carbon density under conservation tillage. In addition, the potential of conservation tillage was further explored to increase the soil carbon pools. The simulation was finally performed on the growth potential of soil organic carbon density under different straw return scenarios, according to the parameters of crop residue coverage in the DNDC model. The results show: 1) The DNDC model was feasible in this case. The R2 value reached 90% for the soil organic carbon under different farmland measures, and the RRMSE values were all within 10%. The relatively better performance was used to simulate the local soil organic carbon density and long-term forecasts. 2) Soil organic carbon storage in cornfields increased significantly over the past 20 years, from 6.08×108 to 1.22×109 t. The reason was closely related to the expansion of the cultivated land area. The soil organic carbon density varied between 4.46 and 98.09 t/hm2 at the county scale, while there was a variation between 3.34 and 139.2 t/hm² at the grid scale. The overall density of soil organic carbon showed a spatial distribution pattern of high in the central region and low in the northern region. 3) Conservation tillage posed a more significant impact on the organic carbon accumulation in the surface soil. The highest growth rate of soil organic carbon density in the 0-10 cm soil layer was 0.44%, while only 0.29% was found in the 10-20 cm soil layer. 4) The huge growth potential of soil organic carbon was observed in the southwestern and central regions in the growth range from 0.24 to 0.57 t/hm², particularly with the increase of crop residue coverage. 5) The fineness of the unit division dominated the simulation. There were slightly different values of the simulation under different units. But there was no spatial distribution of the research subjects. Compared with the spatial distribution after simulation at the county level, the grid scale was indicated in much more detail. In summary, the conservation tillage significantly increased the soil organic carbon in cornfields. The farmland ecosystem shared great potential for carbon sequestration in the future. However, there are local differences in the response of soil organic carbon to the conservation tillage. Therefore, the finding can provide an important reference for the decision-making on conservation tillage tunable for local conditions and carbon budget in farmland ecosystems. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim To study whether genetically predicted serum testosterone level is causally associated with systemic multisite atherosclerosis. Methods Based on two pooled databases of genome-wide association studies on testosterone and atherosclerosis in European populations from two separate foreign countries, the causal effect between testosterone and atherosclerosis was assessed using two-sample Mendelian randomization analysis with data on testosteroneassociated genetic variants as instrumental variables (IV), and by using the inverse-variance weighted (IVW) method, MR-Egger regression, and weighted median estimation. Results IVW results showed that genetically predicted circulating testosterone levels were negatively associated with the risk of peripheral atherosclerosis (OR=0. 93, 95%CI: 0. 86 ~ 1. 00, P =0. 01), and that elevated testosterone level may reduce the risk of developing peripheral atherosclerosis, while no evidence of a potential causal association was found with cerebral atherosclerosis, coronary atherosclerosis and other atherosclerosis type (P>0. 05). Conclusion The final analysis showed a causal relationship between genetically predicted testosterone level and the risk of developing peripheral atherosclerosis, and the role of testosterone therapy in the prevention and treatment of atherosclerosis deserves attention and further study. [ABSTRACT FROM AUTHOR]

Copyright of Machine Tool & Hydraulics is the property of Guangzhou Mechanical Engineering Research Institute (GMERI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of the Chinese Ceramic Society is the property of Bulletin of the Chinese Ceramic Society Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Economic Science is the property of Modern Economic Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Power Automation Equipment / Dianli Zidonghua Shebei is the property of Electric Power Automation Equipment Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Education Theory & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Buoy, island stations, and platform stations play a crucial role in advancing atmospheric and ocean sciences by providing essential marine observational data. This paper explores the potential impact of assimilating sea-based observation data from the South China Sea and the coast on forecasts of heavy rainfall during annually first rainy seasons in South China. In addition to ground station observations, seabased observations are added to conduct continuous cycle assimilation experiments. The experiment results suggest that the continuous cycle assimilation scheme significantly improves precipitation forecasting compared to the cold-start assimilation scheme. The assimilation of additional sea-based observations effectively enhances the humidity field and wind field at the lower levels of the analysis field, thereby improving the water vapor transport and dynamic conditions in the South China Sea region. While the assimilation of sea-based observations does not show significant improvement in precipitation forecasts over land areas, it notably enhances precipitation forecasts for coastal and offshore regions, particularly for heavy rainfall forecasts at 18 - and 24-hour lead times. Overall, the inclusion of sea-based observations positively contributes to the prediction of heavy rainfall along the coastal and offshore regions of the South China Sea during annually first rainy seasons. This study provides an important basis for the CMA-MESO model to achieve more operational assimilation of sea-based observations, improve heavy rainfall forecasting in South China, and conduct marine observation experiments in the South China Sea. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Zone Research / Ganhanqu Yanjiu is the property of Arid Zone Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Plastics / Zhongguo Suliao is the property of Journal Office of CHINA PLASTICS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hydrobiology / Shuisheng Shengwu Xuebao is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hydrobiology / Shuisheng Shengwu Xuebao is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To observe the effects of Bushen Huatan recipe combined with acupoint catgut embedding on sex hormone,glucose and lipid metabolism and Toll like receptor 4/nuclear transcription factor-κB (TLR4/NF-κB) signal pathway of peripheral blood monocytes in patients with polycystic ovary syndrome (PCOS) with kidney deficiency and phlegm dampness syndrome. Methods: According to the random number table method, 80 patients with PCOS with kidney deficiency and phlegm dampness syndrome who came to Cangzhou Integrated Traditional Chinese and Western Medicine Hospital of Hebei Province from October 2019 to October 2021 were divided into control group (40 cases, treated with conventional western medicine) and observation group (40 cases, treated with Bushen Huatan recipe combined with acupoint catgut embedding). After treatment, the clinical effects, as well as the TCM syndrome score, sex hormone, glucose and lipid metabolism and TLR4/NF-κB signal pathway related indexes of peripheral blood monocytes before and after treatment of the two groups were compared. Results: The total clinical effective rate of the observation group was higher than that of the control group (P<0.05). Compared with the control group after treatment, the total score of TCM symptoms of the observation group was lower (P<0.05). Compared with the control group after treatment, the levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), total testosterone (T) of the observation group were lower, and the level of estradiol (E2) was higher (P<0.05). Compared with the control group after treatment, the levels of total cholesterol (TC), triacylglycerol (TG), fasting insulin (FINS), glycosylated hemoglobin (Hb Alc) and insulin resistance index (HOMA-IR) of the observation group were lower (P<0.05). Compared with the control group after treatment, TLR4, NF-κB, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) m RNA of the observation group were lower (P<0.05).Conclusion: Bushen Huatan recipe combined with acupoint catgut embedding can effectively improve the levels of sex hormone, glucose and lipid metabolism in patients with PCOS with kidney deficiency and phlegm dampness syndrome, which possibly by inhibiting TLR4/NF-κB signaling pathway plays a role by activating and reducing inflammatory response. [ABSTRACT FROM AUTHOR]

Copyright of Fire Safety Science is the property of Fire Safety Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Soil & Water Conservation is the property of Bulletin of Soil & Water Conservation Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chongqing University of Posts & Telecommunications (Natural Science Edition) is the property of Chongqing University of Posts & Telecommunications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)