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波纹钢搭接接头作为装配式波纹钢地下工程结构的薄弱环节，在轴力-弯矩作用下的力学行为亟待研究。依托前期足尺试验，结合数值模拟方法，分析了螺栓数量及波纹钢板厚度对搭接接头破坏模式和抗弯承载能力的影响机理，探讨了搭接接头的优化设计方案，建立了极限弯矩经验公式。研究结果表明：我国规范的螺栓设计安全冗余较高，接头破坏模式主要表现为受压侧波纹钢板屈曲。单波螺栓数量越多、波纹钢板越厚、轴力越小，波纹钢搭接接头的抗弯承载能力越强；单波螺栓数量每增加2个，接头极限弯矩平均增长5.9%；波纹钢板厚度每增加2 mm，接头极限弯矩平均增长21.9%；当单波螺栓数量为6个、波纹钢板厚度大于6 mm时可兼顾安全性和经济性。极限弯矩经验公式的拟合优度较高，可为接头强度校核提供参考。

为明确摩擦型高强螺栓连接接头的受力性能，建立了不同角度、不同摩擦系数、不同连接板厚度及不同螺栓杆直径的连接件的数值模型，并研究了压剪组合作用下不同参数连接件的破坏模式、初始滑移荷载及极限荷载。研究结果表明：连接件的破坏模式主要分为螺栓剪断、连接板螺栓孔挤压破坏及连接板屈曲3种；摩擦系数越大，连接件的初始滑移荷载和极限荷载越大，摩擦系数对角度较小的连接件的初始滑移荷载和极限荷载影响更为明显；角度越大，连接件的初始滑移荷载和极限荷载越小，角度对摩擦系数较大的连接件的初始滑移荷载和极限荷载影响较为显著；板厚对连接件的初始滑移荷载影响不大，但对极限荷载影响较大，连接板越厚，极限荷载越大；连接接头的初始滑移荷载和极限荷载与螺栓杆直径成线性关系，螺栓直径越大，连接接头的初始滑移荷载与极限荷载越大。研究结果可为钢结构梁柱斜撑设计及节点加固改造提供参考。

表面改性是使材料表面获得与其基体不同微观组织的处理技术，能够有效调控材料表面的力学性能。因此，将表面改性方法应用于改善硬质合金表面的微观组织，能够有效避免均匀结构硬质合金显微结构–宏观性能的局限性，为制备高性能非均匀结构硬质合金提供技术方案。由于硬质合金表面改性研究的起步较晚且表面改性方法较多，表面改性方法的选取及其改性机理依然面临思路不清的问题。本文总结了化学表面改性梯度硬质合金的材料体系、制备机理、微观结构及力学性能，概括了物理表面改性得到的硬质合金涂层方法与功能，综述了表面改性在硬质合金领域的应用和研究进展，以期为制备高耐磨和高韧性的非均匀结构硬质合金提供参考。

旨在讨论智能绿色时代下港口工业的现状需求、体系结构、新形态和其关键平台技术等问题。首先介绍了智慧绿色时代下港口工业的现状和需求，并详细描述了平行港口工业体系结构与新形态；然后讨论了智慧绿色时代下港口工业中的工业智联网、知识自动化和人机混合增强智能等新一代技术；最后讨论了平行港口在智慧绿色时代中的具体应用场景和案例，重点围绕港口船舶管理系统进行分析。

目的探讨行经皮冠状动脉介入手术（PCI）的冠心病（CHD）患者中不同脂蛋白a［Lp（a）］水平，是否与术后1年内发生主要不良心血管事件（MACE）相关。方法连续选取2013-2014年在我院住院行PCI术并于1年后完成随访的CHD患者297例。记录患者1年内发生MACE情况，MACE定义为再发心绞痛入院治疗、非计划性再次血运重建、急性心肌梗死、急性左心衰竭、心源性死亡。通过单因素和多因素的生存分析比较不同Lp（a）水平的患者术后1年内MACE发生的差异。结果297例患者平均无事件生存时间为（11.41±2.04）月。发生MACE的患者共30例，MACE发生率为10.1%。将患者分为Lp（a）≤150 mg/L、150 mg/L＜Lp（a）≤300 mg/L、Lp（a）＞300 mg/L 3组，经过构建无事件生存曲线并使用Log-rank检验比较3组患者的生存曲线后发现Lp（a）＞300 mg/L的患者MACE发生率较高。使用Cox风险比例回归模型进行多因素校正，作为定量变量Lp（a）升高是CHD患者PCI术后1年MACE发生的危险因素［hazard ratio（HR） per 1-SD increase 1.76， 95% confidence interval（CI）： 1.41～2.19， PP=0.001）。结论Lp（a）水平越高，CHD患者PCI术后1年内MACE发生率越高，Lp（a）是CHD患者PCI术后1年MACE发生的独立危险因素。

【目的】探讨不同程度阻塞性睡眠呼吸暂停（OSAS）的高血压患者肾素、血管紧张素Ⅱ 、醛固酮的水平是否与血压水平相关。【方法】选取 2018 年 11 月至 2019 年 12 月在中山大学附属第三医院心内科住院的初次诊断为高血压并完善了睡眠呼吸监测的患者，排除继发性高血压、NYHA Ⅱ-Ⅳ级心力衰竭、停用影响RAAS 激素水平药物未达 1 月的患者。OSAS 的严重程度采用阻塞性睡眠呼吸暂停低通气指数（AHI）表示，检测患者卧位血浆肾素浓度、血管紧张素Ⅱ和醛固酮水平，记录患者入院后使用降压药前所测量的血压。根据AHI 水平将患者分为两组，其中 A 组 AHI

【目的】评估门诊高血压患者不同血压控制水平间容量负荷的差异，探讨门诊高血压患者的临床因素对容量负荷的影响，分析门诊高血压患者临床基线特点及降压药物使用情况。【方法】在2017年7月至11月期间，纳入门诊高血压患者共514例。记录患者的临床指标，包括性别、年龄、身高、体质量、高血压年限、血压水平、高血压治疗方案及合并症情况。采用生物阻抗分析仪，检测细胞外液与身体总水比值（ECW/TBW），对人体容量负荷进行评估，全身ECW/TBW≥0.39定义为高容量负荷。分析各种临床因素对高血压患者容量负荷的影响，以及降压方案之间容量负荷是否存在差异。【结果】门诊高血压患者血压达标率仍很低，为15.37%。男性患者的血压达标率比女性低。年龄越大、BMI越高、腰臀比越高、高血压病程越长的患者，血压越难控制。血压分级越高，联合用药的比例越高。利尿剂仍是使用最为广泛的降压药。年龄、性别和不同高血压分级为高血压患者容量负荷主要影响因素，女性、高龄、收缩压越高，容量负荷越高。其中年龄是影响高血压患者容量负荷最重要的因素。【结论】门诊高血压患者血压达标率仍低，有效降低容量负荷为控制血压的重要手段之一，在女性、老年、收缩期高血压更为重要。

【目的】探讨冠心病患者脂蛋白胆固醇、载脂蛋白各个指标尤其是 LDL-C 与 HDL-C、apoA1 与 apoB100的相关性，以及各个指标及比值与冠脉病变严重程度的相关性。【方法】选取2013-2014年在中山大学附属第三医院住院接受PCI术的冠心病患者301例，入院后检测患者术前空腹血脂（包括TG、TC、LDL-C、HDL-C、 apoA1、apoB100），用 Gensini 评分表示冠脉病变严重程度。根据 Gensini 评分结果将患者分为 A 组（

【目的】通过球囊损伤兔髂动脉造成动脉损伤的动物模型，观察四逆汤对损伤后动脉内膜的保护作用，并探讨四逆汤对一氧化氮（NO）系统的影响。【方法】雄性新西兰大白兔24只，随机分为对照组、模型组、四逆汤治疗组（四逆汤组），每组8只，对照组兔予普通饲料，模型组、四逆汤组兔予以高脂饮食。饲养2周后模型组、四逆汤组兔行髂动脉内膜剥脱术，对照组兔行假手术。术后4周处死各组实验兔，通过透射电镜观察髂动脉内膜的病变情况，并检测兔血清NO水平和总NOS活性；通过免疫组化观察eNOS蛋白在血管壁的表达，RT-PCR方法检测血管壁eNOS mRNA的表达。【结果】模型组兔髂动脉内膜可见大量的泡沫细胞，内皮细胞脱落；而四逆汤组损伤减轻。模型组兔血清NO水平和总NOS活性明显低于四逆汤组和对照组；四逆汤组和对照组eNOs蛋白和eNOS mRNA表达较模型组明显增强，而四逆汤组和对照组之间无显著性差异。【结论 】 四逆汤可减轻兔髂动脉剥脱术后的内膜损伤，其机制可能与促进髂动脉损伤后内膜eNOS的蛋白和基因的表达，增加NO的产生有关。

【目的】探讨内源性u-PA及u-PAR在不同类型冠心病患者中的临床意义。【方法】急性心肌梗死(AMI)组30例,不稳定型心绞痛(UA)组25例,稳定型心绞痛(SA)组20例,非冠心病(NCAD)组30例,分别检测四组研究对象入院时及入院后2周血浆u-PA浓度和全血中性粒细胞表面u-PAR表达率。【结果】四组研究对象入组时和入组后2周血浆u-PA浓度及全血中性粒细胞表面u-PAR表达率差异均有统计学意义,AMI组明显高于UA组(P0.05);入组后2周血浆u-PA浓度及全血中性粒细胞表面u-PAR表达率与入组时比较差异无统计学意义(P>0.05)。【结论】不同类型的冠心病患者,内源性u-PA及u-PAR的变化情况是不同的,稳定型心绞痛即有上升趋势,不稳定型心绞痛升高较明显,而急性心肌梗死升高最明显。

【目的】探讨辛伐他汀含药血清对U937单核细胞源巨噬细胞基质金属蛋白酶-9（MMP-9）及金属蛋白酶组织抑制因子-1（TIMP-1）表达与分泌的影响。【方法】15只新西兰大白兔随机分为正常对照组（NL,n=5）、粥样硬化模型组（AS,n=5）和辛伐他汀含药血清组（SIM,n=5）。通过喂养高脂饲料,建立兔动脉粥样硬化模型后,予辛伐他汀药液灌胃,获得含药血清。分别予不同浓度含药血清（5%、10%、20%）培养U937单核细胞源巨噬细胞24 h,应用逆转录聚合酶链反应检测MMP-9 mRNA及TIMP-1 mRNA的表达,以及应用酶联免疫吸附试验检测MMP-9及TIMP-1蛋白的分泌。【结果】与相同浓度AS组比较,5%、10%、20%SIM组U937单核细胞源巨噬细胞MMP-9 mRNA表达均显著性降低（P值为0.005、0.041和0.013）;5%、10%、20%SIM组TIMP-1 mRNA表达无显著性差异（P值均〉0.05）。而与相同浓度AS组比较,不仅10%、20%SIM组MMP-9分泌显著性减少（P值分别为0.009和0.001）,而且10%、20%SIM组TIMP-1分泌均显著性增加（P值分别为0.017和0.001）。【结论】辛伐他汀可抑制单核巨噬细胞MMP-9的表达和分泌,以及促进TIMP-1的分泌。

【目的】探讨血管紧张素Ⅱ受体拮抗剂伊贝沙坦对糖尿病大鼠心脏的保护作用及其相关机制。【方法】将30只Wistar大鼠随机分为正常对照组、糖尿病组和伊贝沙坦组3组,每组10只。造模后12周终止实验处死大鼠,取血、尿和心脏标本,测定尿量、体质量、心脏质量/体质量、血糖、糖化血红蛋白(HbA1c);测定血液和心脏组织的丙二醛(MDA)和超氧化物歧化酶(SOD)的活性;通过电镜观察心肌超微结构的变化。【结果】12周终止实验时糖尿病各组大鼠的尿量、心脏质量/体质量、血糖、HbA1c、血清和心脏组织的MDA水平均明显高于正常组,而体质量、红细胞和心脏组织的SOD活性明显低于正常组(P

【目的】观察人骨髓间充质干细胞（mesenchymal stem cells，MSCs）在保存人羊膜及兔眼表结膜基质上分化的情况。【方法】24只新西兰兔随机分为2组。实验组：培养有人MSCs的羊膜移植组，将人MSCs接种在保存人羊膜上培养4d，用5-溴脱氧尿嘧啶（BrdU）标记后移植到兔眼表结膜缺损区；对照组，单纯羊膜移植组。分别于移植后1，2，3，4，6和8周，摘取各组实验眼行组织学和免疫组织化学检查，组织学检查移植到兔结膜基质的MSCs的存活、形态变化以及移植局部的反应等情况；免疫组织化学检测移植到结膜基质的带有BrdU标记的细胞角蛋白3／12（CK3／CKl2）和角蛋白13（CK13）的表达。【结果】MSCs接种到羊膜后能在羊膜上生长，与羊膜共培养4d后，MSCs贴附羊膜生长迅速，组织学特征无明显改变。用羊膜负载MSCs移植到兔结膜缺损区，术后免疫组织化学检测结膜上皮层CK13表达阳性，CK3／CK12表达阴性，在重建的结膜上皮层可检测到BrdU核阳性细胞，未见异常增殖细胞。【结论】人羊膜可作为MSCs的载体，采用人羊膜负载MSCs行兔结膜移植，MSCs能在兔结膜上皮层存活并增殖。

［目的l研究2型糖尿病患者的血管内皮依赖性舒张功能。［方法l采用高分辨率超声，测定21例正常人和31例2型糖尿病患者的胧动脉反应性充血后，以及含服硝酸甘油后的血管内经和血流菌的变化J结果］两组间空腹血糖、餐后2h血糖差异有统计学意义(P< 0. 01), 而性别、年龄、甘油三百扩总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、收缩压、舒张压、体质桩指数差异均无统计学意义(P> 0, 05)。2型糖尿病组反 应性充血后血管内径变化率rC9. o土4,9)'k I'S (J5. 5士3.0)%,(P

【目的】探索一种简便的冠状静脉逆灌注方法, 了解其有效性和安全性。【方法】健康成年犬13 条, 随机分为逆 灌注组(n =7)和对照组(n =6)。开胸结扎左冠状动脉前降支(LADA), 逆灌注导管经右颈外静脉送入冠状静脉窦并进一步 插至心大静脉(GCV)远端, 动脉血由左颈总动脉引出, 以自身动脉血压为动力进行持续逆灌注。逆灌注组于LADA 结扎后5 min 开始持续逆灌注, 共6 h ;对照组同样进行插管但不灌注。观察血流动力学、心电图、血清生化及形态学改变。【结果】逆 灌注组血流动力学较稳定(P

【目的】探讨保留自体巩膜而避免损伤眼外肌的羟基磷灰石义眼座植入法。【方法】选择22 例(22 只眼)单眼无 光感患者施行保留自体巩膜和眼外肌的羟基磷灰石义眼座植入手术, 该组病例年龄7 ～ 67 岁, 平均29.1 岁, 男15 例, 女7 例, 3 例为白塞氏病, 9 例为陈旧性眼外伤继发角巩膜葡萄肿, 8 例为陈旧性眼球穿通伤继发眼球萎缩, 2 例为绝对期青光眼继发 大泡性角膜病变。眼球内容剜除术后剪断视神经和中央血管, 仅离断外直肌而不切开巩膜, 把羟基磷灰石义眼座从颞侧植入 肌锥, 再把外直肌复位。【结果】9 例(9 只眼)患者早期炎症反应重, 3 周后所有病例球结膜充血和水肿完全消失, 安置义眼外 观理想, 追踪观察平均12 个月未发现结膜裂开和义眼座暴露现象。【结论】保留自体巩膜的羟基磷灰石义眼座植入法是一种 效果确切、可避免眼外肌损伤的手术方法。

目的】分析多孔羟基磷灰石(HA)义眼台眶内植入后的并发症并探讨其原因。【方法】回顾眶内植入羟基磷灰石 义眼台320 例, 随诊6 月～ 4 年。【结果】320 例中发生并发症的有46 例(14.4 %), 其中义眼台暴露41 例(12.8%), 义眼台位置 异常2 例, 其它并发症包括义眼台慢性感染、结膜肉芽肿等。义眼台暴露的发生时间为术后7 d～ 6 月, 范围为2 ～ 15 mm 。【结 论】羟基磷灰石义眼台眶内植入最常见的并发症是义眼台暴露, 并发症的发生原因与多种因素有关, 包括术前眼病史、包裹义 眼台的异体巩膜的排斥溶解、义眼台的选择、缝合技术、术后眼眶的放射治疗等。

【目的】评价先天性睑裂狭小综合征的手术治疗效果。【方法】对 50 例先天性睑裂狭小综合征, 采用改良 Y-V 矫 正联合内眦韧带缩短法矫正内眦赘皮,缩短内眦间距,3 个月后二期行额肌瓣悬吊术矫正上睑下垂。【结果】经随访 6 个月～ 5 年, 证实能达到矫正内眦赘皮,延长睑裂 ,缩短内眦间距和充分上提上睑的目的, 治疗效果满意。【结论】改良 Y-V 矫正联合 内眦韧带缩短法和额肌瓣悬吊术是治疗先天性睑裂狭小综合征的效果确切、简便又安全的手术方法。

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The performances of piezoelectric PN junction photovoltaic cells are closely related to the internal potential barrier configurations and the distributions of carriers, and can be tuned through carrier transport characteristic changes by the piezopotentials under the piezo-effect. However, the classical PN junction model fails to describe the coupling effect between multiple physical fields and carriers in the potential barrier zone due to the depletion layer assumptions and others, and in turn gives severely distorted results. Herein a mechanics-electricity-photonics-carrier global multi-field coupling model was developed to investigate the tuning mechanism for mechanical loadings on the output characteristics of ZnO photovoltaic cells. The numerical results indicate that, the short-circuit current, the open-circuit voltage, and the maximum output power of the photovoltaic cell increase with the compressive stress under a fixed light intensity, while tensile stresses are not conducive to improving the performances of photovoltaic cells. In addition, a better tuning effect occurs with a loading region wider than the illuminated region, or with both these two external fields acting in the same side of the n/p-zone. [ABSTRACT FROM AUTHOR]

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Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Angiostrongylus cantonensis (A. cantonensis) has a complex life history and a variety of hosts, and is highly infectious and pathogenic, which poses a serious health threat. The invasion of exotic molluscs has become an important way for A. cantonensis to spread. More and more studies have been conducted on the infection of A. cantonensis by invasive mollusks, and the detection technology of A. cantonensis in the host has been improved gradually. However, the literatures on the infection of A. cantonensis with invasive mollusks are still scattered, there is still a lack of systematic analysis on the susceptibility characteristics and detection techniques of invasive mollusks infected with A. cantonensis. Therefore, the research on invasive mollusks infected by A. cantonensis in the last 20 years was reviewed, and the research progress on infection types, susceptibility, physiological response, genetic profile, host response and detection methods of A. cantonensis infection in invasive mollusks was systematically analyzed. At least 15 species of globally invasive mollusks that are susceptible to A. cantonensis have been reported so far. The larvae (L1-L3) could be parasitized by Pomacea canaliculata, Pomacea maculata/insularum, Achatina fulica, Cipangopaludina chinensis, and Corbicula fluminea. Nitrogen metabolism and oxidative metabolism of infected mollusks were enhanced after infection. The susceptibility of invasive mollusks to A. cantonensis was related to host species, developmental period, breeding environment, infection dose and infection duration. The morphological and molecular methods was often used to detect A. cantonensis. The accuracy of molecular detection method is higher than that of the morphological method. Angiostrongylus cantonensis can spread globally by hitchhiking on invasive mollusks. Simultaneously elucidated the dispersal mechanism of invasive mollusks and the parasitic behaviors of A. cantonensis can provide a useful reference for the prevention, control and management of A. cantonensis. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Materials Engineering / Cailiao Gongcheng is the property of Journal of Materials Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Jinan University (Social Science Edition) is the property of Jinan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Railway Construction Technology is the property of Railway Construction Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South-Central Minzu University (Natural Science Edition) is the property of Journal of South-Central Minzu University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Exploring the evolution of water quality purification triggered by land use change is important for protecting and improving water quality and achieving sustainable development. Taking the “ Two Lakes and One Reservoir” basin as an example, the patch-level land use simulation ( PLUS ) model and the integrated valuation of ecosystem services and tradeoffs ( InVEST ) model ecosystem service water quality purification module were used to simulate changes in the spatial and temporal patterns of land use types as well as the characteristics of water quality purification of the basin under future natural development scenarios and ecological protection scenarios based on the land-use data for the years 2000, 2010 and 2020. The response relationship was quantitatively reveal between land use change and water purification function. The results show that the land type of the “ Two Lakes and One Reservoir” basin is dominated by arable land, and in 2030, the area of arable land, forest land and grassland under the natural development scenario shows a decreasing trend, and the area of construction land shows an increasing trend, and the ecological protection scenario can effectively protect the spatial distribution and area of the basin’ s arable land and forest land, etc. The TN and TP outputs of the “ Two Lakes and One Reservoir” basin are dominated by the low-intensity outputs, and the outputs of TN increase firstly and then decrease, and TP outputs increase year by year during the period of 2000—2020. From 2000 to 2020, TN output first increases and then decreases, TP output increases year by year, and the water purification capacity shows a steady trend. In 2030, TN output continues to decrease under the natural development scenario, and TP output shows an upward fluctuation, and TN and TP output under the eco-protection scenario is reduced compares with that under the natural development scenario, and the eco-protection scenario can increase the water purification capacity. Ecological land types can effectively intercept N and P into the water body, and the ecological protection scenario effectively reduces the rate of change of ecological land types and reduces the output of TN and TP. The future planning of the “ Two Lakes and One Reservoir” basin should increase the proportion of ecological land, and increase the ability of land types to intercept TN and TP. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To detect the expression levels of Ki-67 and isocitrate dehydrogenase 1-R132 H (IDH1-R132 H) in central nervous system glioma cells and to explore their clinical significance. Methods A total of 41 patients with surgically resected and pathologically confirmed brain gliomas were included in this study. Thirteen normal brain tissue samples obtained from patients undergoing craniotomy for head trauma and spontaneous intracerebral hemorrhage were used as a control group. Immunohistochemistry was employed to detect and compare the protein expression levels of Ki-67 and IDH1-R132 H in glioma and control groups. Results The positive rate of Ki-67 in grade Ⅲ-Ⅳ tumors (93.7%) was significantly higher than that in grade Ⅰ-Ⅱ tumors (45.4%), with a statistically significant difference between the two groups (χ²=11.748, P＜0.05). Ki-67 was not expressed in normal brain tissue. The positive rate of IDH1-R132 H in grade Ⅱ and Ⅲ tumors (83.3%) was significantly higher than that in grade I and IV tumors (47.0%), with a statistically significant difference between the two groups (χ²=6.047, P＜0.05). IDH1-R132 H was not expressed in normal brain tissue. There was a statistically significant difference in Ki-67 expression between the IDH1-R132 H negative and positive groups (χ~2=4.055, P＜0.05), with a significant negative correlation (r=-0.314, P＜0.05). Conclusion The expression levels of Ki-67 and IDH1-R132 H can guide clinical practice in patients with gliomas, providing a certain reference basis. [ABSTRACT FROM AUTHOR]

Unmanned aerial vehicle (UAV) and ground-based photogrammetry have been essential to the forest resource surveys, due to the low cost, high efficiency and scalability. However, the complex and heterogeneous nature of forest environments can often lead to the UAV platforms with the less understory information. While the ground platforms can frequently miss the canopy details. The information gaps can be caused by different observation perspectives from UAVs and ground platforms. Some challenges are also remained to efficiently register photogrammetric point clouds. In this study, a point cloud registration was proposed for forest images, according to three-dimensional (3D) point cloud from UAV and ground photogrammetry. Key points of feature were then extracted using coarse-to-fine registration, including the tree top and the ground-level tree center. The specific procedures were as follows: 1) Image Point Cloud Acquisition. In UAV platforms, DJI Phantom 4 RTK UAV were used to capture plot images via oblique photogrammetry. In ground platforms, a "simulated flight path" was employed to obtain the plot images. 3D reconstruction was implemented to generate 3D point cloud data. 2) Feature Point Extraction. Single tree segmentation was combined with AABB bounding boxes and Euclidean clustering. The highest points of individual UAV tree canopies were extracted as feature points. Euclidean clustering was used on ground image point clouds. Single trees were then segmented to extract the ground-level tree center as ground feature points. 3) Coarse Registration. Feature points were mapped from 3D to 2D. Transformation relationships were calculated using improved simulated annealing, partial/full point pair transformation and scale adjustment. The coarse registration was achieved in the original point cloud. 4) Fine Registration. Precise registration was achieved to reduced further error using iterative closest point. A series of tests were performed on six sample plots with different tree species. The results demonstrated the following: 1) The high accuracy and reliability were validated experimentally in the single tree segmentation with AABB bounding boxes and Euclidean clustering. 2) The better performance and stability were achieved in the forest image point cloud registration with improved simulated annealing and iterative closest point. The average errors of coarse and fine registration were 0.09 and 0.06 m, respectively, in the six sample plots. The coarse registration was closely matched the fine registration, indicating the refined registration of image point clouds from UAV and ground platforms. 3) Poplar trees shared a greater impact on coarse registration, compared with ginkgo and catalpa trees. While there was the minimal impact of different tree species on the fine registration. 4) Scale differences were emerged as the influencing factors on forest image point cloud registration. It was necessary to consider and correct during registration. Therefore, cross-platform registration was successfully implemented on the forest image point clouds using UAV and ground-based photogrammetry. A promising approach was presented to tackle the challenges of forest image point cloud registration. This finding can also provide the sound support to forest resource surveys, and 3D forest reconstruction in the wide application of image point clouds. Furthermore, the practical insights can be offered for the precision and intelligent forestry production. [ABSTRACT FROM AUTHOR]

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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