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目的分析酒精相关犯罪嫌疑人的犯罪行为特征，探索犯罪行为特征与刑事责任能力的关系。方法收集酒精相关犯罪嫌疑人的基本信息、酒精使用信息、作案前后精神症状、犯罪学行为特征及鉴定意见。结果慢性酒精中毒组的饮酒史25.0 （13.3~30.0）年显著长于急性酒精中毒组1.2 （0~14.3）年。慢性酒精中毒组85.0%每日饮酒次数不少于1次，52.5%有晨饮或睡前饮酒习惯，92.5%以独饮为主。酒精中毒暴力性犯罪占比57.6%。慢性酒精中毒者作案时精神状态52.5%存在谵妄，急性酒精中毒者作案时精神状态84.6%存在朦胧状态。慢性酒精中毒组42.5%为病理性动机作案，急性酒精中毒组69.2%为现实动机作案。急性酒精中毒组96.2%被评定为完全刑事责任能力，慢性酒精中毒组50.0%被评定为完全刑事责任能力。结论与急性酒精中毒犯罪嫌疑人相比，慢性酒精中毒者的饮酒史长，饮酒频率高、有明显的晨饮或睡前饮酒习惯。酒精中毒犯罪案件性质多为暴力性犯罪。与慢性酒精中毒组相比，急性酒精中毒组的作案动机具高度选择性，多被评为完全刑事责任能力。

目的探讨体表光学图像引导技术（SGRT）联合图像引导放疗技术（IGRT）在乳腺癌术后放疗中实施等中心双引导复位的可行性，评估新的复位模式相对于传统复位模式的误差精度差异。方法回顾性分析2021年7月13日至2022年10月15日在中山大学肿瘤防治中心ELEKTA infinity加速器放疗的乳腺癌保乳术后患者，按不同复位方式分为模拟机复位组（模拟组）41例和双引导复位组（双引导组）40例。模拟组采用模拟机进行复位，首次用CBCT扫描并记录摆位误差；双引导组采用体表光学设备AlignRT引导摆位并联合CBCT进行等中心双引导复位，记录CBCT配准获取的摆位误差。分别计算并比较两种复位方式的胸壁靶区（CROI）的整体摆位误差、患侧锁骨头区域（SROI）的局部残余误差和复位时间，分析SGRT联合IGRT双引导复位的CBCT误差值分布的优点。结果模拟组和双引导组在CROI区域的整体摆位误差（X/cm、Y/cm、Z/cm、Rx°、Ry°、Rz°）中，除了Ry、Rz方向无统计学意义（P>0.05）外，其他方向摆位误差具有统计学意义（PP>0.05）外，其他方向均具有统计学意义（Pt=-24.555，P=0.000，差异具有统计学意义（P

采用ABAQUS有限元分析软件，研究内置工字形CFRP型材方钢管混凝土构件在侧向冲击荷载作用下的受力性能。通过考虑动态响应下材料的应变率效应来计算材料强度，并建立有限元模型对冲击全过程、应力-应变关系以及构件的耗能状态进行研究。通过变换冲击能量、含钢率、剪跨比和材料强度等条件，对构件抗冲击性能进行参数分析。研究结果表明，内置CFRP工字型材使得构件具有更好的耗能和变形能力；随着冲击能量和剪跨比的增长，构件的跨中挠度增大，抵抗冲击所需的时间延长；冲击力峰值受混凝土强度影响甚微，但随着冲击能量、含钢率和钢管屈服强度的增大而明显增加。

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Copyright of Journal of Xi'an Jiaotong University is the property of Editorial Office of Journal of Xi'an Jiaotong University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To analyze the data of the artificial intelligence cervical cancer screening project in Baoding in 2021, understand the effect and existing problems of cervical cancer screening in Baoding, and provide a basis for improving the prevention and treatment of cervical cancer in the rural women population. Methods Screening data for married rural women aged 35-64 from three counties in Baoding City in 2021 were collected, and the data of precancerous lesions and cervical cancer screening was analyzed. Results The results show that artificial intelligence-assisted cervical cancer screening identified 863 cases of positive cytology, with a positivity rate of 7.94%. Additionally, 542 women with positive cytology underwent colposcopy, which revealed 18 cases of low-grade lesions, 20 cases of high-grade lesions, and 1 case of cervical cancer. There were statistically significant differences in the detection rates of AUSCS+, low-grade lesions, and high-grade lesions across three counties in Baoding from 2019 to 2021 （ χ2 = 858.90, P < 0.001； χ2 = 14.28, P=0.003; χ2 = 10.75, P = 0.013） . Conclusion The artificial intelligence cervical cancer screening project has shown some success, but there are still issues like a high rate of missed abnormal cases. The screening and prevention efforts for cervical cancer in Baoding City need further improvement. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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：目的　探讨乙酰半胱氨酸雾化吸入联合阿奇霉素序贯治疗小儿肺炎支原体肺炎（MPP）的临床效果。 方法　选择 MPP患儿 215例，随机分为联合治疗组 72例、雾化吸入组 72例、序贯治疗组 71例。雾化吸入组予吸入 用乙酰半胱氨酸溶液雾化吸入治疗，序贯治疗组予盐酸阿奇霉素注射液静脉滴注、阿奇霉素干混悬剂口服序贯治 疗，联合治疗组予吸入用乙酰半胱氨酸溶液雾化吸入联合阿奇霉素序贯治疗，三组均连续治疗14天。治疗14天结 束，比较三组临床疗效；治疗前和治疗 14 天结束，比较三组临床症状或体征消失时间以及血清免疫球蛋白（IgA、 IgM、IgG）、心肌酶谱［肌酸激酶同工酶MB（CK-MB）、谷草转氨酶（AST）、乳酸脱氢酶（LDH）、心肌肌钙蛋白（cTn）］和 炎症因子［CRP、IL-6、IL-33、TNF-α、可溶性程序性死亡受体1（sPD-1）］水平；比较三组治疗14天内不良反应发生率。 结果　联合治疗组总有效率高于雾化吸入组和序贯治疗组（P均<0. 05），而雾化吸入组与序贯治疗组总有效率比较 差异无统计学意义（P>0. 05）。联合治疗组咳嗽、发热、肺部阴影、肺部啰音消失时间均显著低于雾化吸入组、序贯 治疗组（P均<0. 05），而雾化吸入组与序贯治疗组比较差异均无统计学意义（P均>0. 05）。三组治疗后血清免疫球 蛋白（IgA、IgM、IgG）、心肌酶谱（CK-MB、AST、LDH、cTn）及炎症因子（CRP、IL-6、IL-33、TNF-α、sPD-1）水平均低于治 疗前，并且联合治疗组治疗后上述指标均低于雾化吸入组和序贯治疗组（P均<0. 05），而雾化吸入组与序贯治疗组 治疗后上述指标比较差异均无统计学意义（P均>0. 05）。三组治疗期间不良反应发生率比较差异无统计学意义（P> 0. 05）。结论　乙酰半胱氨酸雾化吸入联合阿奇霉素序贯治疗小儿 MPP不仅能快速缓解临床症状或体征，还能降 低机体免疫球蛋白、减轻心肌损伤、抑制气道炎症，安全有效。 [ABSTRACT FROM AUTHOR]

Weeds are one of the most serious pests to agricultural production, and their control mainly depends on chemical herbicides. Long-term and large-scale use of chemical herbicides will lead to the increase of weed resistance, environmental security and food security. Microbial herbicides are biological herbicides developed by using microorganisms themselves or their metabolites, which are characterized by abundant resources, environmental friendliness, not easy to have resistant weeds, which are the development direction of green weed biocontrol in the world. In this paper, we summarized the types of microbial herbicides and listed the biocontrol microorganisms and toxins with herbicidal activity. Then, we reviewed the mechanism of microbial weed control. Microorganisms invaded the weed host through infection, causing the tube closure of the weed, and finally resulting in plant wilting and dying. In otherwise, they affected the cell structure integrity, biofilm function, lipid stability, energy transfer, photosynthetic pigment synthesis, lipid synthesis and amino acid synthesis of the weed host through effective active substances in metabolites, to achieve the purpose of killing weeds. In addition, we summarized the application status of microbial herbicides, including commercialization, constraints in application and improvement strategies of control effect; as well as the application of omics technology in the field of microbial herbicides. Finally, we prospected the development direction and application prospect of microbial herbicides，aiming to provide reference for the research and development of new herbicides. [ABSTRACT FROM AUTHOR]

Bone and soft tissue tumors occur in the musculoskeletal system, and malignant bone tumors of bone and soft tissue account for 0.2% of all human malignant tumors, and if not diagnosed and treated in a timely manner, patients may be at risk of a poor prognosis. Image interpretation plays an increasingly important role in the diagnosis of bone and soft tissue tumors. Artificial intelligence (AI) can be applied in clinical treatment to integrate large amounts of multidimensional data, derive models, predict outcomes, and improve treatment decisions. Among these methods, deep learning is a widely employed technique in AI that predominantly utilizes convolutional neural networks (CNN). The network is implemented through repeated training of datasets and iterative parameter adjustments. Deep learning-based AI models have successfully been applied to various aspects of bone and soft tissue tumors, encompassing but not limiting in image segmentation, tumor detection, classification, grading and staging, chemotherapy effect evaluation, recurrence and prognosis prediction. This paper provides a comprehensive review of the principles and current state of AI in the medical image diagnosis and treatment of bone and soft tissue tumors. Additionally, it explores the present challenges and future prospects in this field. [ABSTRACT FROM AUTHOR]

Copyright of Study on Optical Communications / Guangtongxin Yanjiu is the property of Study on Optical Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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AIM: To investigate the effect of Huangqi-Danggui decoction (HQDG) on the brain tissue of rats with cerebral ischemia/reperfusion (I/R) injury for 7 d by regulating macroautophagy and chaperone-mediated autophagy (CMA), and to explore its mechanism. METHODS: Male SD rats were randomly divided into sham group, model group, HQDG group and Xuesaitong (XST) group. Determination of main chemical components of HQDG by liquid chromatography-mass spectrometry. The model of middle cerebral artery occlusion/reperfusion in rats was established by the left modified thread embolism method, and the changes of cerebral blood flow were observed by laser speckle blood flow imager. Zea Longa score was used to observe the neurological deficit. HE staining was used to observe the degree of nerve cell injury. The changes of neurovascular unit and autophagosomes in brain tissue were observed by transmission electron microscopy. Immunohistochemical method was used to detect the expression of LC3, P62, lysosome-associated membrane protein-2A (LAMP-2A), heat shock protein 70 (HSP70) and myocyte enhancer factor 2D (MEF2D) proteins. Western blot was used to detect the expression of autophagy-related proteins P62 and LC3-II/LC3-I. RESULTS: Compared with the sham group, the neurological deficit score in model group was significantly higher (P<0. 01). A large number of nerve cells showed necrosis and nuclear dissolution, with the cell arrangement being disordered. The number of autophagosomes increased. The protein expression levels of LC3, LAMP-2A, HSP70 and MEF2D in brain tissue increased, while the ex⁃ pression level of P62 protein decreased (P<0. 05 or P<0. 01). Compared with the model group, the scores of neurological deficit in brain tissue in HQDG and XST groups were significantly lower (P<0. 01). Cell damage was significantly re⁃ duced. The number of autophagosomes further increased. The expression levels of LAMP-2A, HSP70, MEF2D and P62 proteins in brain tissue decreased, while the expression levels of LC3-II/LC3-I protein increased (P<0. 05 or P<0. 01). CONCLUSION: HQDG can alleviate cerebral ischemia/reperfusion injury in rats and exert neuroprotective effects by activating macroautophagy and reducing CMA. [ABSTRACT FROM AUTHOR]

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In order to clarify the optimal spore production and inoculation methods for watermelon stem blight (Stagonosporosis cucurbitaceae), and to lay a solid foundation for the screening and identification of watermelon stem blight resistant germplasm resources, this article focuses on the spore production and inoculation methods of watermelon stem blight. Two common spore production methods were compared from the aspects of spore production time, spore yield, and spore morphology of stem blight. It was found that the UV induced spore production method had shorter spore production time, more stable spore yield, normal spore morphology, and lower cost compared to the cucumber induced spore production method. Currently, it was the best spore production method for watermelon stem blight. Watermelon resistant and susceptible materials were also inoculated with the methods of inoculum cake in vitro, spot inoculation with live spore suspension, and spray inoculation with live spore suspension, respectively. The three inoculation methods were compared in terms of operation difficulty and accuracy, and it was found that each of the three inoculation methods had advantages and disadvantages. The difference of resistance and susceptibility of watermelon resistant and susceptible materials was obvious after inoculating in vitro with cake inoculation and in vivo spore suspension spot inoculation, while the susceptible materials showed moderate resistance after inoculating in vivo spore suspension spray inoculation. Through comparison, it was found that the in vitro bacterial cake inoculation method and the live spore suspension point grafting method were more reliable, but the disease grading standards of the in vitro bacterial cake inoculation method were not precise enough, and the small differences in resistance between materials were difficult to reflect; the live spore suspension point grafting method had high accuracy, but the operation was complex, time-consuming, and labor-intensive; in vivo spore suspension spray inoculation method was simple in operation, but it was difficult to accurately control the amount of inoculum, and the accuracy was general. Therefore, it was suggested that the live spore suspension spray inoculation method could be used for preliminary screening when identifying the resistance of large quantities of materials to Fusarium wilt, and the live spore suspension spot connection method could be used when identifying the resistance of a small number of materials to Fusarium wilt, and the isolated cake inoculation method could be used as an auxiliary method to further verify the inoculation results. [ABSTRACT FROM AUTHOR]

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目的 机械取栓时代，探索如何因地制宜建立急性卒中救治体系，让更多急性卒中患者能在时间窗 内及时到达有条件的医院，从而提高区域性急性卒中急诊救治的整体水平。 方法 从2014年开始，在院内及医院所在的区域，由单位行政部门及区域卫生行政部门牵头协调， 制定卒中救治的相关政策、规定，陆军军医大学第一附属医院神经内科作为技术主导，开展卒中诊治 的培训及帮助各级部门、医院建立相应的卒中救治流程、规范。观察我院卒中救治的关键绩效指标 及协作单位救治水平的改善情况。 结果 ①院内急诊通道的建立：由院长亲自参与，院医疗科作为卫生行政部门进行督导、协调，院内 参与卒中救治的急救部、神经内科、神经外科、神经影像科、检验科、心电图室及护理保障中心积 极参与，使急性缺血性卒中的入院-静脉溶栓（door-to-needle time，DNT）时间由绿色通道建立前的 71 mi n缩短至53 mi n，入院-动脉穿刺（door-to-puncture time，DPT）时间由104 min缩短至82 min，入院-血 运重建（door-to-revascularization time，DRT）时间由144 min缩短至117 min。②区域性卒中救治网络的建 立：极大提高我院急性缺血性卒中的救治能力，2014年本科静脉溶栓及血管内治疗总病例数为7例， 2016年提高到112例，区域内初级卒中中心的卒中防治关键绩效指标明显改善。 结论 院内卒中救治绿色通道及区域性卒中救治网络的建立，能提高卒中救治水平及救治率，改善 区域性卒中救治水平。应进一步改进卒中救治通道及网络并进行更大范围的推广。 Abstract: Objective In the context of current era of mechanical thrombectomy, this study is to explore how to establish acute stroke emergency system suited for local condition, make more stroke patients arrive at the qualified hospitals within the therapy time window, and increase the overall level of regional stroke rescue treatment. Methods Since 2014, the hospital and regional health administrative departments began to assist the local hospitals to make the policy and regulation of stroke rescue. The Department of Neurology of the Third Military University Affiliated First Hospital took the lead in aspect of technique, developed the training of diagnosis and treatment of stroke, provided assistance in establishing rescue workflow and assisted the collaborative hospitals to establish stroke emergency workflow and criterion. The improvement of key performance indicator (KPI) of acute ischemic stroke (AIS) care of our hospital, and change of stroke rescue level of collaborative hospitals were observed. Results (1) Establishment of stroke fast channel: the hospital director participated in the work. The department of medical affairs carried out the monitoring and coordination work. Many departme actively participated in the work, including Emergency, Neurology, Neurosurgery, Neuroimaging, Laboratory Medicine, ECG, and Nursing Security. The door-to-needle time (DNT) was shortened from 71 minutes before to 53 minutes now; the door-to-puncture time (DPT) was shortened from 104 minutes before to 82 minutes now; the door-to-revascularization time (DRT) was shortened from 144 minutes before to 117 minutes now. (2) Establishment of regional stroke rescue network: the level of AIS emergency care of our hospital got greatly improved. The total number of patients treated with IV thrombolysis and endovascular treatment increased from 7 in 2014 to 112 in 2016; the KPIs of stroke care in primary stroke center in this region also got improved significantly. Conclusion The establishment of in-hospital stroke fast channel and regional stroke rescue network can increase the level of stroke emergency care and regional stroke cure rate. It’s worthwhile to be further improved and widely promoted.

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Copyright of Journal of Hainan Medical University is the property of Journal of Hainan Medical College Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)