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目的探讨嗜粘蛋白阿克曼氏菌在新生期母婴分离（MS）和避水应激（WAS）肠易激综合征（IBS）大鼠模型的内脏高敏发生中的作用。方法将SD雄性大鼠在新生期随机分为3组：sham WAS（空白组），MS+WAS组（IBS模型组）及阿克曼氏菌组（Akkermansia muciniphila， A. muciniphila组），IBS模型组及阿克曼氏菌组采用母婴分离联合避水应激方法（MS+WAS）建立内脏高敏感模型。母婴分离刺激结束后，阿克曼氏菌组每天避水应激处理同时灌胃1 mL 1×109 CFU/mL A. muciniphila连续10 d。再用行为学观察和腹部回缩反射评分来检测内脏痛反应。结果经阿克曼氏菌干预后，实验组大鼠与模型组相比，体质量显著增加；粪便颗粒数及其不成形率显著下降；内脏疼痛阈值则显著上升。阿克曼氏菌组大鼠结肠黏膜内2型大麻素受体（CB2R）mRNA表达相比模型组显著上升。结论阿克曼氏菌可能通过调控结肠的CB2RmRNA表达来缓解IBS大鼠的内脏高敏。

Objective To observe the early rehabilitation outcomes of the first-time artificial total hip arthroplasty (THA) using the direct anterior approach (DAA). Methods Sixty patients who underwent unilateral THA for the first time at Huangshan People's Hospital from 2020 to 2021 were selected, including 30 cases of THA using the direct anterior approach (DAA group) and 30 cases of THA using the posterior-lateral approach (PLA group). The surgical incision length, intraoperative blood loss, duration of drainage tube placement, time to first ambulation after surgery, quality of life, complications, pain, and joint function recovery were compared between the two groups. Pain was assessed using the Visual Analog Scale (VAS) at 1 week, 4 weeks, and 12 weeks postoperatively. Hip joint function was evaluated using the Harris Hip Score (HHS) scoring system, and quality of life was assessed using the S-36 questionnaire. Results The DAA group had a shorter incision length and less intraoperative blood loss compared to the PLA group, and time to first ambulation was earlier and duration of drainage tube placement was shorter in the DAA group compared to the PLA group, with a significant difference (P＜0. 05). At 4 and 12 weeks postoperatively, pain VAS scores, Harris scores, and quality of life were higher in the DAA group compared to the PLA group, with a significant difference (P＜0. 05). There was a case of dislocation of hip prosthesis and a cased of periprosthesis infection in the PLA group, and no postoperative complications reported in the DAA group. Conclusion Compared with PLA approach, THA using the DAA approach results in smaller trauma and faster recovery, aligning with the concept of rapid rehabilitation and showing better clinical efficacy. (目的 探讨首次人工全髋关节置换术(THA)直接前方入路(DAA)的早期临床康复效果。方法 选取2020年1月—2021年12月在黄山市人民医院首次接受单侧THA的患者60例, 其中直接前方入路(DAA)THA 30例(DAA组), 后外侧入路(PLA)THA 30例(PLA组)。比较两组患者手术切口长度、术中出血、引流管留置时间、术后首次下床时间、生活质量、并发症、疼痛及关节功能恢复情况, 在术后1周、术后4周、术后12周应用视觉模拟量表(VAS)评价疼痛, 应用Harris髋关节评分系统(HHS)评价髋关节功能, 应用健康调查简易量表(SF-36)评价生活质量。结果 DAA组切口长度、术中出血量少于PLA组, 首次下床时间早于PLA 组, 引流管留置时间短于PLA 组, 差异有统计学意义(P＜0. 05)。DAA组患者术后4周、术后12周疼VAS评分、Harris评分、SF-36量表评分均高于PLA组, 差异有统计学意义(P＜0. 05); PLA组术后出现1例髋关节假体脱位, 1例出现假体周围感染; DAA组无并发症发生。结论 与PLA比较, DAA入路行THA创伤更小, 恢复更快, 符合快速康复理念, 早期临床康复效果更佳。)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the value of multiple ultrasound indicators in the prognosis evaluation of congenital diaphragmatic hernia and provide scientific rationales for an accurate diagnosis and treatment of congenital diaphragmatic hernia (CDH). Methods From January 2018 to December 2022, preoperative ultrasonic images were retrospectively reviewed for 92 CDH children undergoing neonatal surgery. The relevant indicators included length of diaphragmatic defect (≤4 cm & >4 cm), location of liver (liver hernia & non liver hernia) and gastric vesicles (left/right), hernia sac (yes or no) and whether or not lung ultrasound was abnormal. According to their prognosis, they were divided into two groups of death and survival. And the relationship between each indicator and the prognosis of children (death or survival) was statistically examined. Results Among them, 70 survived and 22 died with a case fatality rate of 23.9%. Comparing survival group with death group, the difference in the proportion of herniation into liver [(25.7% (18/70) vs. 54.5% (12/22)], presence of hernial sacs [survival group: 72.9% (51/70), death group: 50.0% (11/22)] and presence of ultra sonographic abnormality in lungs [survival group: 48.6% (34/70), death group: 81.8% (18/22)] were statistically significant (all P < 0.05 ) . Multivariate Logistic regression analysis indicated that diaphragmatic defect length >4 cm OR = 4.513, 95% * CI / 1.12 18.184 ), liver herniation into chest OR = 3.636, 95% * CI / 1.171 11.29 ), lung ultrasonic abnormalities OR = 3.64, 95% * CI / 1.022 12.963 ) and an absence of hernia sac (OR = 3.428,95% CI:1.066-11.025) were risk factors for a poor prognosis of CDH. Kappa values for diaphragmatic defect length >4 cm, liver herniation into chest, absence of hernia sac and lung ultrasonic abnormalities were <0.6 whereas Kappa value for a combination of these four parameters was 0.788. Conclusions Diaphragmatic defect length, liver location, hernia sac and lung function may be employed as prognostic indicators for CDH children. And a combination of the above four parameters can more accurately predict the outcomes of CDH children. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Empowering the innovation and transformation of red cultural resources with digital technology is an important trend to promote the sustainable development of red cultural resources. The logical mechanism of the innovation and transformation of red cultural resources, empowered by digital technology, is manifested in the fact that digital processing technology provides guarantee for resource transformation, digital reproduction technology provides support for resource activation, digital media technology provides a platform for resource dissemination, and blockchain technology provides a platform for resource reproduction. In this process, it faces practical challenges such as weak top-level design, technical barriers, insufficient talent support, and single communication media. The key to promoting the innovation and transformation of red cultural resources lies in perfecting the policy system, speeding up the infrastructure construction, establishing the warehousing database, building a sharing platform, improving the talent training mechanism, optimizing the talent introduction mechanism, and opening up all channels and strengthening the scenario experience. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background--In the context of the slow progress of multilateral free trade negotiations in the World Trade Organization (WTO), regional trade agreements (RTA), mainly in the form of free trade agreements (FTA), are spreading rapidly around the world. With the rise of FTA, researches on the background, effects and determinants of FTA have been published increasingly. But so far, the research on trade rules of FTA forest products signed by China hasn't started yet. To sum up, on the basis of sorting out the country characteristics and product characteristics of FTA tariff concessions and rules of origin that China has signed, the overall characteristics of trade rules of China's FTA Forest product are comprehensively analyzed and the reasons are explored. ⑵ Methods--Through classification and statistics of forest products' tariff concession pattern and rules of origin in six FTAs signed by China, Chile, New Zealand, Iceland, Switzerland, Australia and South Korea, the characteristics of tariff concession pattern and rules of origin of China' FTA forest products are analyzed from the country level and product level. Then it summarizes the different trade rules of FTA forest products adopted by China for different partner countries and products and explores the reasons. The data come from each FTA text and its annex of China Free Trade Zone Service network, FAO Forest Products Yearbook and UN COMTRADE DATABASE. ⑶ Results--First, China only promised to abolish tariffs on 60% of forest products, but basically all FTA forest products of six countries promised to abolish tariffs on forest products of China, indicating that China's FTA tariff concessions on forest products is relatively conservative, while the six countries are extremely open to China. Secondly, the majority of the rules of origin of forest products in China's FTA are subject to changes in items. The trade restrictions of rules of origin are relatively loose, and the setting of rules of origin of forest products is not precise. Third, the tariff concession pattern and rules of origin adopted by China for different FTA partners and forest products are not completely consistent. For non-sensitive products, China adopts a strategy of combining tariff concession and item change, which are mainly concentrated in wood raw materials, wood pulp, cork and wooden furniture. There are three ways to protect sensitive forest products. The first is the double protection strategy of tariff protection and rules of origin protection. The second is the cross-protection strategy of tariff protection and rule of origin protection. The third is the cross-protection strategy of rule of origin protection and tariff protection. ⑷ Conclusions and Discussions--China adopts different trade rules for different countries and forest products based on domestic wood resource supply and demand, forest product trade characteristics, competitiveness and other factors. For raw material and resource-intensive forest products, tariff elimination is adopted, unilateral restrictions are imposed on more sensitive forest products in terms of tariffs or rules of origin, and only a few of the most sensitive forest products are protected by double-protection strategy. It is clear that China' s FTA forest products trade rules still need to be improved. First, the proportion of exception case is too high. In fact, in consideration of protection and opening-up, China can appropriately increase the number of forest products for which tariffs will be phased out in the medium and long term. In addition, a country like Iceland, which has less than 1 % forest coverage and very little trade in both imports and exports, could reasonably increase openness. Secondly, the setting of rules of origin for forest products is not precise. China's basic strategy is to take tariff protection as the main means of trade restriction, while rules of origin in many cases only serve as an auxiliary means of restriction. China can strengthen the protection of rules of origin and set more detailed and precise rules of origin for different forest products to compensate for the adverse effects of a single tariff protection approach. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Clinical Pediatric Surgery is the property of Journal of Clinical Pediatric Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chemical Engineering of Oil & Gas / Shi You Yu Tian Ran Qi Hua Gong is the property of PetroChina Southwest Oil & Gas Field Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

镇痛和镇静是儿科重症监护病房(PICU)治疗中必不可少的环节,其目的是减少疼痛、焦虑,防止意外拔管,提高 患儿与机械通气的同步性,遗忘不愉快的回忆。目前,最常用的镇痛药物仍是阿片类药物,常用的镇静药物有苯二氮类、苯巴比 妥、异丙酚及右美托咪定。同时,选择合适的评估量表监测PICU 患儿镇痛镇静状态,可减少不良反应的发生,降低对患儿精神和 心理伤害,缩短住院时间。 [ABSTRACT FROM AUTHOR]

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)