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The planting-breeding integration system is an important pathway to achieve the sustainable development of both animal husbandry and crop yield. Currently, the large-scale farming leads to highly concentrated animal waste, which is difficult to manage and process in a short period. Moreover, the manure contains environmental risks such as organics, heavy metals, antibiotics and antibiotic-resistant genes, which affect the existing ecological cycle system. Hydrothermal technology can convert animal waste into bio-oil, hydrochar, aqueous products, and gas products, with potentials in fuel, soil improvement, phytopathogen control, and greenhouse gas fertilization applications, respectively. According to over a decade of researches, an ecological cycling agricultural model called "planting-breeding integration system based on hydrothermal resource utilization" is proposed. This article systematically reviews the role and application potential of hydrothermal conversion products from animal waste: discusse the current research status of hydrothermal conversion of animal waste into bio crude oil as fuel for agricultural internal combustion engines; elucidates the role of aqueous products as potential agricultural fungicides in crop disease prevention and control; summarizes the research progress of hydrochar from animal waste in physicochemical characteristics, and field application; and analyzes the components of gas-phase products and their potential for greenhouse planting. Through calculation based on previous studies, hydrothermal conversion technology has significant energy and ecological benefits in constructing a new type of integrated farming model. Taking fresh swine manure with a water content of 80% as an example, after hydrothermal conversion, the produced bio-oil can generate approximately 2 000 MJ of energy as fuel; the aqueous product contains high contents of nitrogen and phosphorus elements, presenting significant potential as fertilizer and exhibits important anti-pathogen efficacy. Additionally, the produced 0.1-0.12 t of hydrochar via hydothermal conversion holds important carbon sequestration ability. Furthermore, through hydrothermal treatment, heavy metals in manure are efficiently immobilized, and pathogens and antibiotics are also rendered harmless, facilitating safe subsequent application of manure. Under this model, it will help increase the land's capacity to assimilate animal manure, construct an ecologically sustainable green circular agriculture, and achieve efficient management of animal manure and agriculture residuces. However, this model is still in a conceptual stage, and conducting large-scale application still faces significant challenges. On this basis, this article summarizes the main challenges and shortcomings of this model, and looks forward to the research direction of recycling application of animal waste and hydrothermal conversion products. Evaluating the ecological and environmental safety of aqueous products and hydrochar in field applications is an urgent task: Establishing standard procedures for hydrothermal conversion to obtain stale products, and systematically analyzing the ecological safety, environmental migration pathways, and toxic effects of conversion products are important prerequisites for promoting the development of this plantingbreeding integration system. Demonstrating the technical and economic feasibility and production safety this system is another issue that needs to be addressed. Constructing factories to achieve on-site treatment of animal waste, and coupling with various economic and renewable energy sources to support the hydrothermal conversion process are important means to improve the economic feasibility. This article will provide a reference for the high-value utilization of animal manure via hydrothermal conversion and the research of a highly-efficient planting-breeding integration system. [ABSTRACT FROM AUTHOR]

Objective To evaluate the prognosis-related factors after surgical operation of patients with brain metastasis of lung adenosquamous carcinoma. Methods A total of 185 patients with lung ASC who only had brain metastasis were collected from United States Surveillance, Epidemiology, and Final Results Registry（SEER database） from 2010 to 2019. According to the follow-up results in 2019, patients with lung adenosquamous carcinoma brain metastasis were divided into surgery group（n=38） and non-surgery group（n=147）. The clinical data of 2 patients with lung adenosquamous carcinoma with brain metastasis in Cancer Hospital of Chinese Academy of Medical Sciences Peking Union Medical College were reviewed, and the related factors affecting overall survival（OS） were compared and analyzed. Univariate and multivariate Cox regression was used to analyze the independent risk factors affecting the prognosis of patients with brain metastasis, and the KM survival curve of independent risk factors was analyzed. Cox regression proportional hazard model was used in multivariate analysis to obtain the independent risk factors affecting the long-term prognosis of patients with brain metastasis of lung adenosquamous carcinoma. Results The median OS of 185 patients with brain metastasis was 6. 0 months. The median OS of patients with surgery alone was 3. 0 months,and that of patients with surgery combined with radiotherapy and chemotherapy was 10. 0 months,the difference was statistically significant（ P = 0. 001）. The results of single factor analysis showed that age（ HR = 0. 302,95% CI: 0. 137-0. 663,P = 0. 003）,postoperative radiotherapy for brain metastasis（ HR = 2. 242,95% CI: 1. 093-4. 599,P = 0. 028）,chemotherapy（ HR = 4. 166,95% CI: 1. 911 ～ 9. 081,P = 0. 000）,treatment modalities（ HR =3. 307,95% CI: 1. 556-7. 027,P = 0. 002） were the factors affecting the OS of surgical patients with brain metastasis. And primary site operation（ HR = 2. 963,95% CI: 1. 486-5. 908,P = 0. 002）,chemotherapy（ HR = 1. 843,95% CI: 1. 286-2. 640,P = 0. 001） were the factors affecting the OS of unoperated patients with brain metastasis. The results of multivariate analysis showed that chemotherapy（ HR = 0. 247,95% CI: 0. 077 ～ 0. 791,P = 0. 019） was an independent prognostic factor affecting OS in surgical patients with brain metastasis. Primary site operation（ HR = 2. 877,95% CI: 1. 477-5. 718,P = 0. 003）,chemotherapy（ HR = 0. 551,95% CI: 0. 384-0. 790,P =0. 001） were the independent prognostic factors of OS in unoperated patients with brain metastasis.Conclusion Chemotherapy and primary surgery can affect the prognosis of patients with brain metastasis of lung adenosquamous carcinoma. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的探讨胰酶肠溶肢囊在治疗慢性胰腺炎伴胰腺外分泌不足的临床疗效及并发症c方法选择2014年 2月至2015年12月该院收治的70例慢性胰腺炎伴胰腺外分泌不足患者作为研究对象，将其随机分为观察组和对照组， 各35例，对照组给予常规慢性胰腺炎治疗，观察组在对照组治疗基础上给予胰酶肠溶胶囊治疗，周后对两组临床疗效 及并发症进行对比分析。结果观察组脂肪摄取指数和蛋白氮摄取指数均明显高于对照组，差异均有统计学意义(P<0.05)。 治疗后，两组患者的粪便平均脂肪含量、粪便含氮量、大便频率、大便质量均低于治疗前，且观察组显著低于对照组，差异 均有统计学意义(P<0.05)。两组均无严重药物不良反应及死亡事件发生，观察组和对照组不良反应总发生率分别为28.6%、 25.7%，二者比较，差异无统计学意义(P0.05)。结论对慢性胰腺炎患者应用胰酶肠溶胶囊治疗的临床疗效确切，有助 于改善胰腺外分泌不足的临床症状，并可促进患者对营养物质的吸收，改善患者的总体营养状况，适宜临床推广应用。 [ABSTRACT FROM AUTHOR]