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BACKGROUND: Relevant studies have shown that the sagittal parameters of the spine and pelvis of patients with thoracolumbar osteoporotic compression fractures change to varying degrees, which can lead to an imbalance of the thoracolumbar spine. OBJECTIVE: To investigate the correlation between the sagittal parameters of the spine and pelvis and the prognosis of vertebroplasty in the treatment of thoracolumbar vertebral compression fractures. METHODS: Totally 66 patients with vertebral compression fractures undergoing vertebroplasty in the Chongqing Sanbo Chang’an Hospital from May 2017 to June 2019 at the age of 61-79 years were enrolled and included in the observation group. Before operation and 3 months after operation, the patient’s pain and improvement of pelvic function were evaluated by visual analog scale score and Oswestry dysfunction index. The sagittal parameters, Cobb angle, and Beck index of the spine and pelvis were measured by X-rays of the whole spine. Sixty healthy subjects of the same age group (control group) were selected, and the sagittal parameters of the spine and pelvis were measured by X-rays of the spine and pelvis. This study was approved by the Ethics Committee of Chongqing Sanbo Chang’an Hospital (approval No. [2017]52; approval date: 2017-04-26). RESULTS AND CONCLUSION: (1) The visual analog scale score and Oswestry dysfunction index of the observation group were significantly improved 3 months after operation (P < 0.05), and the Cobb angle and Beck index were significantly better than those before the operation (P < 0.05). (2) The pelvic tilt was greater in the observation group than that of the control group (P < 0.05), and the pelvic incidence, sacral slope, lumbar lordosis, thoracic kyphosis, vertical misalignment axis were all smaller in the observation group than those of the control group (P < 0.05). In the observation group, the pelvic tilt was smaller at 3 months after operation than that before operation (P < 0.05), and the pelvic incidence, sacral slope, lumbar lordosis, thoracic kyphosis, and vertical misalignment axis were all greater than those before operation (P < 0.05). (3) Pearson correlation analysis showed that preoperative pelvic incidence angle, pelvic tilt, lumbar lordosis and total effective rate, postoperative visual analogue scale score, Oswestry dysfunction index, Cobb angle and Beck index were correlated (P < 0.05). There was no significant difference between the above-mentioned indicators and the control group at 3 months after operation (P > 0.05). (4) Results indicate that vertebroplasty has a good curative effect in the treatment of vertebral compression fractures. It can significantly relieve pain, correct the pathological curvature of the spine and pelvis, and restore the balance of the spinal column. [ABSTRACT FROM AUTHOR]

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