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This paper reviewed the research progress of serum biomarkers of pulmonary sarcoidosis in recent years. According to the pathophysiological mechanism, they are classified into monocyte/macrophage related markers, T cell and B cell activation markers, acute phase reaction protein and serum calcium. Currently, angiotensin-converting enzyme (ACE) remains the most widely utilized serum biomarker, while other markers such as cell-free proenzyme activator (CTO), soluble interleukin-2 receptor (sIL-2R), and serum calcium are demonstrating promising clinical applications. Despite certain limitations in the diagnostic use of these serum biomarkers, future research may enhance diagnostic accuracy by developing new biomarkers or investigating combinations of multiple biomarkers, thereby advancing early screening and personalized treatment strategies for pulmonary sarcoidosis. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Railway Science & Engineering is the property of Journal of Railway Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Objective/Meaning]With the improvement of people’s material life, the rural homestay has become an important engine to promote the development of rural tourism and rural revitalization. Exploring the development status and prospect of rural homestay can provide theoretical and practical references for promoting the high-quality development of rural tourism and laying solid foundation for rural revitalization.[Methods/Procedures]The SWOT-PEST matrix analytic method was used to analyze the advantages, disadvantages, opportunities and threats of rural homestay development in Turpan of Xinjiang in the four environmental factors of politics, economy, society and technology, and then the countermeasures were put forward accordingly.[Results/Conclusions]The study showed that: the development trend of rural homestay in Turpan was good, but there were still some problems, such as the imperfect infrastructure, insufficient policies and laws, homogenization of homestay quality, and low quality of homestay employees. Therefore, the development of rural homestay in Turpan of Xinjiang could be promoted by improving the relevant policies and laws, standing on the advantages of local homestay development, and maintaining a benign market environment of homestay, so as to accelerate the pace of rural revitalization in Turpan of Xinjiang. [ABSTRACT FROM AUTHOR]

Objective • To evaluate the accuracy and efficiency of the automated supervised machine-learning algorithm for microaneurysm lesion detection in seven-field color fundus photography. Methods • A total of 616 seven-field color fundus photographs were obtained from 44 patients with diabetic retinopathy (DR) from Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine from 2014 to 2016. Using the microaneurysm detection algorithm developed in this study, the automated identification and labeling of microaneurysm lesions in the standard seven-field color photography of DR were performed. The results were compared with manual labeling by ophthalmologists to evaluate the sensitivity and efficiency of the automated algorithm. Results • In the standard seven-field fundus color photographic image library, the automated algorithm achieved sensitivity of 94.15% in total and 93.09% in the optic disc field (Fl), 94.84% in the macula field (F2), 95.16% in the temporal to macula field (F3)> 94.99% in the superior temporal field (F4), 93.77% in the inferior temporal field (F5), 92.40% in the superior nasal field (F6) and 93.75% in the inferior nasal field (F7), and specificity of 98.05% in total and 98.02% in Fl, 98.06% in F2, 97.97% in F3, 97.91% in F4, 98.07% in F5, 98.03% in F6 and 98.23% in F7. The cost of time per image was (9.2± 0.6) s, 93.2% less time than manual labeling. Conclusion • The automated microaneurysm detection algorithm can accurately and efficiently identify microaneurysm lesions in color fundus photography. [ABSTRACT FROM AUTHOR]

Copyright of Guangdong Architecture Civil Engineering is the property of Guangdong Architecture Civil Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To probe into the effects of rivaroxaban on serum HIF-1α, P-selectin and TNF-α of patients with lower extremity venous thrombosis. METHODS: 120 patients with lower extremity venous thrombosis admitted into Hanchuan People’s Hospital from Feb. 2015 to Feb. 2016 were selected to be divided into observation group and control group via the random number table, with 60 cases in each. The control group were treated with conventional treatment, while the observation group additionally received rivaroxaban based on the control group. The treatment effects of two groups were observed. RESULTS: The total effective rate of observation group was 91. 67%(55/60), significantly higher than that of control group [65. 00% (39/60) ]; the level of serum HIF-1α, P-selectin and TNF-α in observation group were significantly lower than those in control group,with statistically significant difference (P < 0. 05). CONCLUSIONS: Rivaroxaban intreatment of lower extremity venous thrombosis can relief the clinical symptoms, decrease level of serum HIF-1α, P-selectin and TNF-α and improve the treatment effects. [ABSTRACT FROM AUTHOR]