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Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Previous studies have found that both high tibial osteotomy and high tibial osteotomy combined with arthroscopy can effectively treat medial compartment osteoarthritis with varus deformity of the knee, but there are few studies comparing the therapeutic effects of the two. OBJECTIVE: To compare the clinical outcome of high tibial osteotomy and high tibial osteotomy combined with arthroscopy to treat degenerative tear in the posterior horn of medial meniscus combined with varus deformity of knee joint. METHODS: From July 2015 to January 2019, data of 48 knee osteoarthritis patients with degenerative tear in the posterior horn of medial meniscus combined with varus deformity of knee joint in Affiliated Hospital of Zunyi Medical University were retrospectively analyzed. The 24 patients in the trial group were treated with high tibial osteotomy combined with arthroscopy. The 24 patients in the control group were treated with high tibial osteotomy. The knee joint function scores and imaging detection indexes at different time points after operation were compared between the two groups. RESULTS AND CONCLUSION: (1) The hospital for special surgery knee score and knee Lysholm score of patients in the trial group at 6 and 12 months after operation were higher than those in the control group (P < 0.05). There was no significant difference in the hospital for special surgery knee score and knee Lysholm score between the two groups at 24 and 36 months after operation (P > 0.05). The visual analogue scale score of patients in the trial group was lower than that in the control group at 6 months after surgery (P < 0.05). There was no significant difference in the visual analogue scale scores between the two groups at 12, 24, and 36 months after surgery (P > 0.05). (2) The imaging examination at 12 months after operation showed that the lower limb alignment and femoral tibial angle were effectively improved in both groups, and the relative positions of the femoral tibial angle and lower limb alignment passing through the tibial plateau and the posterior tibial slope of the tibial plateau were not significantly different between the two groups (P > 0.05). (3) It is concluded that high tibial osteotomy and high tibial osteotomy combined with arthroscopic surgery can effectively treat degenerative tear in the posterior horn of medial meniscus combined with varus deformity of knee joint, effectively improve joint function and relieve pain symptoms. High tibial osteotomy combined with arthroscopy exhibited good early clinical efficacy. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: At present, the mainstream treatment strategy for femoral shaft fracture is surgical treatment, including intramedullary nail fixation, steel plate fixation, and Bridge combined fixation system, which is becoming more and more popular in recent years. However, there are relatively few studies on the biomechanical properties of the three internal fixation methods. OBJECTIVE: To simulate the fracture of the middle femur using finite element technique, and analyze the biomechanical characteristics of locking plate, Bridge combined fixation system, and intramedullary nail internal fixation under different working conditions. METHODS: The CT data of left femur of a healthy volunteer from the Affiliated Hospital of Zunyi Medical University meeting the inclusion and exclusion criteria were collected in this study. The digital model of middle femoral fracture with defect was constructed by Mimics and Geomagic software. According to the principle of internal fixation, the fracture model was assembled with appropriate size locking plate, Bridge combined fixation system, and intramedullary nail respectively after introducing the fracture model into Pro/E software. After geometric cleaning and gridding, the model was incorporated into Abaqus software to analyze the displacement and stress of three internal fixation methods of middle femoral fracture under different stress conditions by finite element analysis. RESULTS AND CONCLUSION: In the results of finite element analysis, three kinds of femoral internal fixation models showed different mechanical properties under different working conditions. (1) Under the loading of vertical stress, the force of the intramedullary nail was uniformly distributed along the direction of the main nail, and the stress was the least, and the Z-shaped deformation of the two connecting rods in the bridging system near the fracture end distributed the overall stress, resulting in the smallest displacement and the best stability. (2) Under the loading of horizontal stress, the stress and displacement of the bridging system were the smallest, and the stability was the best. Stress was concentrated on the 1-3 fixing block on the bridging system connection rod and its adjacent metal components. (3) Under the loading of torsional stress, the displacement of the intramedullary nail was the smallest and the stability was the best, while the stress and displacement of the bridging system were the largest, and the stress was concentrated on the interface between the proximal locking nail and the bone, and the stability was the worst. (4) The results show that the femoral bridging system has good mechanical properties of anti-compression and antibending, while the femoral interlocking intramedullary nail has more advantages in anti-torsion force. As a conventional eccentric fixation, locking plate is less stable in vertical compression and bending, but better resistant to torsion than double-bar bridging system and inferior to the interlocking intramedullary nail. [ABSTRACT FROM AUTHOR]

BACKGROUND: Injury of the posterolateral complex of the knee joint is a common type of multiple ligament injuries of the knee joint. The reconstruction of the posterolateral complex can restore the posterior and lateral stability of the knee joint and rebuild the stability of the knee joint. OBJECTIVE: To discuss the feasibility and clinical effect of modified LaPrade method for functional reconstruction of posterolateral complex of knee with autograft peroneus longus tendon. METHODS: Fourteen patients with posterolateral complex and posterior cruciate ligament injuries who were treated in the Department of Orthopedics, Affiliated Hospital of Zunyi Medical University from October 2014 to March 2017 were enrolled in this study. Posterior cruciate ligament and posterolateral complex were simultaneously constructed in stage one. The injury of the posterolateral complex of the knee joint was Fanelli type C. Modified LaPrade method was used to functional reconstruction of posterolateral complex of knee with peroneus longus tendon. The anatomy and function of the core ligament of the posterolateral complex was simulated. Follow-up time was beyond 1 year. The tibia posterior displacement on stress radiographs, lateral compartment gapping on varus stress radiographs at 0° knee extension, and external rotation angle of tibia at 30° knee flexion were compared before and after surgery. The joint function was evaluated according to the score of International Knee Documentation Committee and Lysholm Knee score. RESULTS AND CONCLUSION: (1) All patients were followed up for 12-18 months. All patients had no knee-length restriction, with flexion limitation in some patients. (2) At the last follow-up, the tibia posterior displacement on stress radiographs, lateral compartment gapping on varus stress radiographs and external rotation angle of tibia at 30° knee flexion were reduced from preoperation, with statistically significant differences (P=0.000). (3) The International Knee Documentation Committee function was corrected from D preoperatively to A in 8 cases and B in 6 cases postoperatively. The average Lysholm score was increased from (32.4±5.6) preoperatively to (82.7±6.4) postoperatively, and the differences were statistically significant (P=0.000). (4) It is indicated that with peroneus longus tendon, the anatomy and function of the core ligament of the posterolateral complex were simulated by modified LaPrade method to functional reconstruction of posterolateral complex of knee, and the postoperative knee function recovered well. [ABSTRACT FROM AUTHOR]