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In this paper, the electronic structures, optical properties and photocatalytic performances of Mo doped into V-site of BiVO4 with different concentrations were investigated using the first nature principles based on density generalized function theory. The results of the defect formation energy calculations indicate that all three doping systems of BiMoxV1-xO4（x=0.0625, 0.125, 0.25） are stable.The electronic structure calculations show that the band gaps of the four systems of BiMoxV1-xO4（x=0, 0.0625, 0.125, 0.25） are 2.123 eV, 2.142 eV, 2.160 eV and 2.213 eV, respectively. The band gap values of the doped BiVO4 system are all larger than that of the intrinsic BiVO4, and the band gap increases with the increase of Mo concentration.The energy band structures of the three doped systems BiMoxV1-xO4（x=0.0625, 0.125, 0.25） are all shifted to the lower energy region, resulting in the doped system conduction band bottom crossing the Fermi energy level, and Mo doped BiVO4 has n-type semiconductor properties.Optical property calculations show that dielectric constants of the intrinsic BiVO4 and three doped systems BiMoxV1-xO4（x=0.0625,0.125,0.25） are 3.08, 3.90, 12.7 and 17.50, respectively, and the static dielectric constants show an increasing trend after doping. The reflection coefficients and the imaginary parts of the dielectric functions for the three doped BiVO4 systems are significantly enhanced in the low-energy region, and the light absorption coefficients of three Mo-doped BiVO4 systems are significantly enhanced for infrared light. The photocatalytic performance calculations showed that the intrinsic BiVO4 oxidation of H2O to O2is the weakest and the BiMo0.25V0.75O4 oxidation of H2O to O2 is the strongest. [ABSTRACT FROM AUTHOR]

The basic chemical properties of mining and metallurgical waste slag and raw materials are measured, and compound strong alkaline activator is developed according to the test results, which can be used to activate the activity of mining and metallurgical waste slag, so as to prepare special backfill cementitious material. The hydration reaction products in the backfill were tested by XRD. The results showed that the main hydration products supporting the strength of backfill were ettringite (AFt), calcium hydroxide (CH), aluminum glue(AH8_10), calcium silicate hydrate(C S H), hydrated calcium aluminosilicate(C A S H), et al. The formation of one ettringite(AFt) molecule will bind and adsorb 32 H2 0 molecules, indicating that the special backfill cementitious material is more suitable for backfill slurry with larger water content. At the same time, SEM was used to analyze the internal structure of the backfill at different ages, revealing the strength growth law of the backfill, and analyzing the strength mechanism of the backfill at each stage. The strength of backfill of two kinds of cementitious materials was tested by strength test under different conditions. The results showed that the strength of backfill prepared by special cementitious materials(KS) was higher than that prepared by cement (SN), there was a one fold difference in the strength value. [ABSTRACT FROM AUTHOR]

[Objective] The nutritional value of 16 varieties in the main producing areas of walnut was clarified, which provided certain theoretical basis for the breeding of improved walnut varieties in China. [Method] From 2018 to 2021, 16 locally promoted walnut varieties were collected from Sichuan, Xinjiang, Yunnan, Shanxi, Gansu and other main producing provinces in China for four consecutive years. The nutritional components of protein, fat, mineral elements (Ca, Fe, Zn, Se), vitamin B1 and vitamin B6 were determined and analyzed by national standard method. [Result] Among the 16 tested walnut varieties, the Guangfeng variety produced in Sichuan had the highest protein and Zn content, the Wen 185 variety produced in Xinjiang had the highest fat content. The Cd and Fe contents of Chuanzao No.2 variety produced in Sichuan were the highest, and the Se content of Shuoxing variety was the highest. The Longnan 755 variety produced in Gansu had the highest content of vitamin B1. Lifeng variety produced in Sichuan had the highest content of vitamin B6. [Conclusion] The contents of protein, fat, mineral elements and vitamins of 16 domestic walnut varieties were higher. The Shuoxing variety was rich in Se elements, which could provide germplasm resources for the subsequent development of Se-rich walnut. [ABSTRACT FROM AUTHOR]

Objective: To investigate the fixation effect of different fixatives on immune organs of SPF grade guinea pigs, and provide reference for screening fixatives suitable for spleen, lymph nodes and bone marrow. Methods: Twenty-one 300-350 g SPF male guinea pigs were randomly divided into 7 groups with 3 in each group. Spleen, mesenteric lymph nodes and iliac bone marrow were extracted. Each group was fixed with 4% polyformaldehyde solution, 10% neutral formalin solution, Bouin's solution, Carnoy solution, Davidson's solution, Zenker solution and Helly solution for 48 h, respectively. Before fixation, iliac bone marrow was immersed in EDTA decalcification solution (pH7.2) and placed in a incubator at 37 ℃ for decalcification. By making paraffin sections and staining with HE, the effects of 7 fixative fluids on section quality were compared from the aspects of section cracking degree, cell morphology and staining effect. Results: The results showed that the white pulp and red pulp of spleen after 10 % neutral formalin solution were clearly colored, no cracks appeared, and the morphology of lymphocytes was easy to distinguish. After fixation with Carnoy solution, the bright and dark areas of the germinal center of the lymph nodes were distinct, the red and blue staining was moderate, and the lymphocyte morphology was clear. After fixation with 4 % paraformaldehyde solution, bone marrow staining was moderate and clearly distinguishable. Conclusion: For tissue fixation at room temperature for 48 h, after HE staining, it is recommended to use 10% neutral formalin solution to fix the spleen, Carnoy solution to fix the lymph nodes, and 4% paraformaldehyde solution to fix the bone marrow, and Bouin's solution to fix the bone marrow if decalcification while fixation is considered. [ABSTRACT FROM AUTHOR]

An 8-week feeding trial was performed to study the effects of replacing fish meal with different levels of Modified corn protein powder and Dried porcine solubles on growth performance, feed utilization and immune performance of Litope⁃naeus vannamei. In our study, 6 groups of isonitrogen and iso-lipid feeds were manufactured by compound protein source replacing 0%, 20%, 40%, 60%, 80% and 100% fish meal, respectively, and named as experimental group CD1 (base feed), CD2, CD3, CD4, CD5 and CD6. Results showed that dietary replacing 20%, 40%, 60% and 80% fishmeal with compound protein source could not significantly affect the weight gain rate (WG) and specific growth rate (SGR) of L. vannamei compared to the control group (P>0.05). However, WG, SGR, feed efficiency (FE), protein productive value (PPV) and feed protein efficiency ratio (PER) in CD6 group was significantly lower than those in CD1 group (P<0.05). Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and triglyceride (TG) levels in serum of CD6 group were significantly higher (P<0.05), while alkaline phosphatase (ALP) and total protein (TP) in serum were significantly lower than those in other groups (P<0.05). The glutathione peroxidase (GPX), superoxide dismutase (SOD) and acid phosphatase (ACP) levels in hepatopancreas of shrimp in complete substitution group (CD6) were significantly lower compared with those in other groups (P<0.05), while MDA level was significantly increased (P<0.05). In conclusion, the growth performance of L. vannamei was not significantly affected when fish meal replaced by compound protein source at a certain level (20%-80%). However, the fish meal completely replaced by compound protein source could significantly decrease the feed utilization, immunity ability and oxidation resistance of L. vannamei. [ABSTRACT FROM AUTHOR]

In order to screen out the seedling tray specifications which could not only meet the needs of well cellar type seedling transplanting in Yibin tobacco-growing area, but also reduce the amount of substrate and seedling rearing site, the effects of different seedling tray specifications on the growth and development of tobacco seedlings and tobacco yield and quality were studied by means of wet seedling rearing. The results showed that the seedlings grew faster in 128 pores per tray and 162 pores per tray, and the agronomic characters, material accumulation and qualified seedling rate were higher. The agronomic characters and economic characters of tobacco plants in the field were higher, but the amount of matrix and the required seedling area were larger, and the input cost of seedling rearing increased obviously. The quality, agronomic characters and economic characters of tobacco plants cultivated in 200 pores per tray were similar to that of 128 pores per tray, but the substrate consumption and the required seedling tray area were 39. 88% lower than that of 128 pores per tray, 30. 77% lower than that of 128 pores per tray, and the cost of seedling rearing was significantly reduced. The seedling quality, agronomic characters and economic characters of tobacco plant in the field were significantly lower than those of other treatments, although the substrate consumption and seedling area required by 288 pores per tray were the lowest. In summary, 200 pores per tray is an ideal choice in Yibin tobacco area. [ABSTRACT FROM AUTHOR]

The effective integration of ideological and political education into the curriculum is the key to improving teaching quality and cultivating high-quality talent. Taking the experiment "Determining the Thermodynamic Functions of Chemical Reactions by Electromotive Force Method" as an example, we have constructed a deep exploratory laboratory inquiry combined with ideological and political education. Through the exploration of the principles and methods of electromotive force determination, as well as the derivation of thermodynamic quantities of reactions, students have not only deepened their understanding of related fundamental theoretical knowledge, enhanced their experimental skills and innovation ability to solve practical problems; they have also strengthened their patriotic sentiments and sense of responsibility. [ABSTRACT FROM AUTHOR]

[Objective]The aims of this study are to clarify the future trend and magnitude of temperature increase in the Loess Plateau, and to provide reference for future temperature change decision-making events, flood control and disaster reduction in the Loess Plateau. [Methods] This study was based on the simulation results of 22 Earth-climate system models in the latest sixth International Coupled Model Intercomparison Project (CMIP6) . After systematically assessing the simulation capability of each model historical period (1961—2014) through observational data, the multi-model ensemble of 10 models was selected to analyze the temperature change characters in the Loess Plateau from 2015 to 2100 under different shared socioeconomic pathways (SSPs) . [Results] The warming rate of the Loess Plateau reaches 0.09℃/decade, 0.28℃/decade, 0.48℃/decade and 0.66℃/decade in 2015—2100 under the SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5 scenarios, respectively. By contrast to 1995—2014, the warming reaches 1.53℃, 2.69℃, 3.83℃ and 5.25℃ in 2081—2100, respectively. Except for the SSP1-2.6 emission scenario, the warming in other scenarios has far exceeded the target of limiting global 2℃ warming in the Paris Agreement, and under the SSP5-8.5 emission scenario, the warming in 2041—2060 has already reached 2.36℃. Under the SSP5-8.5 scenario, even the spring, summer, autumn and winter temperatures in the Loess Plateau from 2081 to 2100 vary in the range of 3.83～4.75℃, 4.75～5.67℃, 4.98～5.67℃ and 4.29～5.67℃ compared to 1995—2014. [Conclusion] The Loess Plateau will face a strong warming pressure in the future, with a higher rate of temperature increase under the higher emission scenarios. The observational research on the temperature of the Loess Plateau should be strengthened in the future. [ABSTRACT FROM AUTHOR]

Climate change has altered the hydrothermal regime and physical characteristics of the active layer, reducing the stability of slopes. Currently, the stability analysis of permafrost slopes is mostly based on the limit equilibrium method. However, this method is difficult to analyze the stability of slopes under the coupled effects of the moisture field, temperature field, stress field, displacement field of the active layer. Therefore, this article integrates the Mohr-Coulomb criterion into the coupled thermo-hydro-mechanical model of unsaturated permafrost, establishes a coupled thermo-hydro-mechanical model of permafrost slopes (THM) to quantitatively analyze the impact of extreme high temperatures in summer on the stability of permafrost slopes. To validate the effectiveness of the model, a landslide in the permafrost region of the eastern Qinghai-Xizang Plateau was selected as the research object. The stability was calculated by constructing both the limit equilibrium model and the THM model, and the relationship between the simulation results and the field observation data were compared and analyzed. The research results show that the simulation results of the THM model are consistent with the calculation results of the traditional limit equilibrium method, and the location of the sliding surface, displacement magnitude, and final shape obtained from the numerical simulation are consistent with the field measurement data. Under extreme high temperature conditions in summer, when the active layer of permafrost melts to a depth of 1.45 m, the slope will become unstable along the melting front, and the sliding surface is parallel to the slope surface. The research results have a certain reference value for understanding the processes of slope collapse and thaw slumping in various engineering projects in cold regions. [ABSTRACT FROM AUTHOR]

In the industrial production environment, strong noise and other environmental stimuli result in similarities in the characteristics of different faults in the diaphragm pump check valve, making it difficult for traditional deep learning methods to accurately identify the valve's fault status. To solve this problem, a method combining supervised contrastive learning and hybrid attention residual neural network (HA-ResNet) was proposed for fault diagnosis of diaphragm pump check valves. Firstly, the attention mechanism was introduced into the residual neural network to enhance the network's learning capabilities. The weights of important but weak features were adaptively adjusted by the attention mechanism, and the suppression of useful information through identity transformations was reduced. Secondly, a weighted “supervised contrastive loss( SCL) + cross-entropy (CE) loss” was proposed to adjust the distances between different fault states of the check valve. The classification boundaries for different fault states were clarified by this method and the interference of noise or environmental stimuli was reduced. Finally, the effectiveness and stability of the method combining supervised contrastive learning and HA-ResNet were verified using real measurement data. The results show that the average accuracy of supervised contrastive learning and HA-ResNet fusion method reaches 99. 3% on the validation set of the diaphragm pump check valve. Comparing with other fault diagnosis methods, supervised contrastive learning and HA-ResNet fusion method has advantages in diagnostic accuracy and stability. The reliability of this method for fault diagnosis under noise interference conditions has been verified. [ABSTRACT FROM AUTHOR]

BACKGROUND: If quadriceps femoris muscle is not effectively rehabilitated, the strength of quadriceps femoris muscle in patients with intertrochanteric fractures will gradually decline, even causing lower limb muscle atrophy. As a result, postoperative complications such as pain in the affected thigh and inflexibility of the hip and knee joints will occur. OBJECTIVE: To evaluate the effect of universal stepwise rehabilitation training of quadriceps femoris muscle on the postoperative rehabilitation of intertrochanteric fracture of the femur, and to investigate the efficacy of quadriceps femoris rehabilitation in the postoperative rehabilitation of intertrochanteric fractures of the femur. METHODS: A retrospective analysis was performed to analyze the data of 48 patients operated for intertrochanteric fracture of the femur who were rehabbed by applying a quadriceps femoris rehabilitation program between October 2016 and February 2022. Rehabilitation training included isotonic and isometric contraction training of quadriceps femoris muscle, and the time of exercise was from the 1st to the 12th week of the postoperative period. Patient’s Hip function was evaluated using hip joint mobility score in Merle D'Aubigne and Postel evaluation system, WOMAC lower extremity function score, and Harris hip joint function score. The Visual Analog Scale was used to assess patients’ pain. The Hospital Anxiety and Depression Scale was used to assess the patient’s psychological status. Changes in quadriceps muscle strength were also measured. RESULTS AND CONCLUSION: The average healing time of the fracture was (9.78±1.65) weeks. At 4 weeks postoperatively, the patient’s hip function significantly improved compared with that at the preoperative period (P < 0.01), the Visual Analog Scale scores for pain evaluation decreased (P < 0.01), quadriceps femoris muscle strength increased (P < 0.01), and the Hospital Anxiety and Depression Scale scores decreased (P < 0.05). At 12 weeks postoperatively, as the rehabilitation training continued, the patient's hip function and pain symptoms further improved compared with those at 4 weeks postoperatively (P < 0.05), quadriceps femoris muscle strength further recovered (P < 0.05), and the Hospital Anxiety and Depression Scale scores further decreased (P < 0.01). At 24 weeks postoperatively, the rehabilitation training had been stopped, the patient’s hip joint function and muscle strength were well maintained, and no obvious amyotrophy occurred in the quadriceps femoris muscle, and there were no significant differences between 12 and 24 weeks postoerpatively (P > 0.05). No complications and adverse events occurred during postoperative rehabilitation. To conclude, the application of universal stepwise functional rehabilitation model of quadriceps femoris muscle in the early postoperative period of intertrochanteric formal fracture is helpful for the recovery of hip joint function, increasing muscle strength, and promoting fracture healing to a certain extent. [ABSTRACT FROM AUTHOR]

In this paper, electronic structures and photocatalytic performances of Si, Ge, Zr and Sn doped SrTiO3 were studied using density functional theory realized by QUANTUM ESPRESSO（QE） software package. The lattice constants of SrTiO3 obtained by using the generalized gradient approximation（GGA） are very consistent with the previous experimental data. At the same time, the lattice constants of SrTi0.875X0.125O3（X=Si, Ge, Zr, Sn） doped systems were obtained. The band gap values of SrTiO3 and SrTi0.875X0.125O3（X=Si, Ge, Zr, Sn） are 1.853 eV, 1.849 eV, 1.916 eV, 1.895 eV and 1.925 eV, respectively. When studying the photocatalytic performance of five SrTiO3 systems, the band gap values of the five SrTiO3 systems were modified by using the scissors operator. The reduction potential(ECB) of the conduction band edge of the intrinsic SrTiO3 and four SrTi0.875X0.125O3（X=Si, Ge, Zr, Sn） doping systems were calculated to be-0.782 eV,-0.736 eV,-0.776 eV,-0.800 eV and-0.791 eV, respectively. The oxidation potentials(EVB) of the valence band edge corresponding to five SrTiO3 systems were calculated as 2.418 eV, 2.460 eV, 2.487 eV, 2.442 eV and 2.481 eV, respectively. From the perspective of redox properties, the redox properties of the two SrTi0.875X0.125O3（X= Zr, Sn） doping systems are improved compared with the intrinsic SrTiO3, while the redox property of SrTi0.875Si0.125O3 is reduced compared with the intrinsic SrTiO3. The relative positions of the band edges of the five SrTiO3 systems can meet the process of water splitting to generate H2 and O2.  [ABSTRACT FROM AUTHOR]

Background Rehabilitation for schizophrenia typically relies on pharmacological interventions, yet their efficacy in improving social function and quality of life remains limited. In recent years, non-pharmacological approaches have shown promise in enhancing rehabilitation outcomes. However, research on the effectiveness of psychomotor therapy specifically for young and middle-aged schizophrenic inpatients is limited. Objective To explore the effects of psychomotor therapy on the rehabilitation of young and middle-aged schizophrenic inpatients, and to provide a reference for treatment strategies. Methods A total of 104 young and middle-aged schizophrenic inpatients who met the International Classification of Diseases, tenth edition (ICD-10) diagnostic criteria and hospitalized in the Fourth People's Hospital of Wuhu from June 2021 to June 2022 were selected. Patients were randomly divided into two groups of 52 each using random number table method. Both groups received treatment with risperidone tablets (2~4 mg/d), along with routine nursing care. Additionally, the research group received an extra 45~55 minutes of psychomotor therapy 2~3 times per week for 12 weeks. The control group received the same psychomotor therapy after the study. Positive and Negative Symptom Scale (PANSS), Scales of Social-skills for Psychiatric Inpatient (SSPI) and Insight and Treatment Attitude Questionnaire (ITAQ) were used to assess the patients before the intervention and at 4th, 8th and 12th week after the intervention. Results The main effects of intervention at different time points for PANSS positive symptoms, negative symptoms and general psychopathology subscale scores, PANSS total score, SSPI score and ITAQ score were all statistically significant (F=33. 989, 204. 245, 82. 817, 279. 596, 26. 144, 7. 463, P<0. 01). Furthermore, statistically significant between-group differences were observed in PANSS negative symptoms and general psychopathology subscale scores, PANSS total score, SSPI score and ITAQ score (F=30. 053, 5. 306, 33. 417, 33. 013, 18. 608, P<0. 05 or 0. 01). Moreover, the interaction effect of time and group were statistically significant for PANSS positive symptoms, negative symptoms and general psychopathology subscale score, PANSS total score and SSPI score (F=3. 472, 9. 798, 3. 843, 14. 390, 20. 661, P<0. 05 or 0. 01). After 12 weeks of intervention, the research group exhibited statistically significantly lower PANSS total score and subscale scores compared with baseline (P<0. 01), while their SSPI total score was significantly higher than that of control group (P<0. 01). Additionally, compared with the control group, the research group had statistically significantly lower PANSS total score and subscale scores, while their SSPI score was statistically significantly higher than those of control group (P<0. 01). Conclusion Psychomotor therapy may contribute to the improvement of the psychiatric symptoms and social function in young and middle-aged inpatients with schizophrenia, enhancing their rehabilitation outcomes. [ABSTRACT FROM AUTHOR]

Objective To analyze survival data of cancer from 1970 to 2014 in Zhongshan City, Guangdong Province, and provide scientific basis for cancer prevention and control in Zhongshan City. Methods The tumor incidence data of Zhongshan City, Guangdong Province from 1970 to 2014 were collected from Zhongshan Cancer Registry, and all patients were followed up to December 31, 2019. The standardized 5-year net survival rates and their annual percentage change (APC) and average annual percentage change (AAPC) for total and major cancers at different times were used to describe statistical analysis. The standardized survival rates were weighted using the International Cancer Survival Standard Age Coefficients. Results There were 78 854 cancer patients eligible for the study in Zhongshan City of Guangdong Province from 1970 to 2014, among which lung cancer (13 466 cases, 17.08%), nasopharyngeal cancer (9715 cases, 12.32%) and liver cancer (9707 cases, 12.31%) were the main types of cancer. The morphology verification was 69.87% in the whole of cancers and the ranges were 21.07% to 97.00% in major cancers. From 2010 to 2014, the 5-year age-standardized net survival rates of cancers for all, males and females in Zhongshan City were 39.74%, 30.92% and 52.47%, in which were 97.98% for thyroid cancer, 74.29% for brain and central nervous system tumors, 73.92% for nasopharyngeal cancer, 50.23% for colorectal cancer, 81.38% for female breast cancer, 78.81% for uterine body cancer, 68.57% for cervical cancer, 49.33% for prostate cancer, 16.19% for lung cancer, 12.14% for liver cancer, and 11.78% for esophageal cancer, respectively. The survival rates of all cancers in Zhongshan City showed an increasing trends in 1970-2014 (AAPC=1.5%, P=0.025), and it was higher in female cancers than that of male in all periods. Conclusion The standardized 5-year net survival rates of all and major cancers in Zhongshan City of Guangdong Province show an increasing trend from 1970 to 2014, but they are still at a medium-low levels compared with the countries and regions participating in CONCORD-3 project, suggesting that Zhongshan should continue to strengthen cancer prevention and control. [ABSTRACT FROM AUTHOR]

This study was to evaluate the effects of fish meal replaced by cottonseed protein on growth performance, feed utilization and intestinal histology of channel catfish (Ictalurus punctatus). A basal diet with 100 g/kg fish meal was designed, and then cottonseed protein was used to replace 0, 20%, 40%, 60%, 80% and 100% of dietary fish meal to formulate six isonitrogenous diets (D1, D2, D3, D4, D5, D6 group). The six diets were fed to channel catfish with an average weight of (171±1) g for 67 days. The results showed that compared with the D1 group, the final body weight and weight gain rate in the D5 and D6 groups were significantly decreased (P<0.05), and the feed ratio was significantly increased (P< 0.05). The hepatosomatic index of the D3, D5 and D6 groups were significantly lower than that of the D1 group (P<0.05). Higher crude protein content of flesh was observed in D6 than that in D1 group (P<0.05). There were no significantly differences in survival, condition factor, viscerosomatic index and the contents of moisture, crude lipid and crude ash of flesh among all groups (P>0.05). When 100% of dietary fish meal was replaced by cottonseed protein, the apparent digestibility coefficient of dry matter and protein were significantly decreased (P<0.05). In intestinal histology, there were no significant differences between intestinal villus height and muscle thickness when fish meal was replaced by cottonseed protein (P>0.05). In summary, in a basal diet containing 10% fish meal, cottonseed protein could replace 60% fish meal without affecting the growth performance, feed utilization and intestinal morphology. [ABSTRACT FROM AUTHOR]

Nitrogen fertilizer is one of the key factors limiting the high yield of potato. At present, the application of nitrogen fertilizer in potato production lacks scientific guidance, and there are widespread phenomena such as excessive nitrogen supply, unreasonable form combination and backward supply mode, which seriously restrict the high yield and efficient production of potato. In this review, the effects of nitrogen supply on tuber formation and development were discussed, and the effects of nitrogen on the initiation of potato stolons, the formation time, quantity and weight of tuber were summarized. Under low nitrogen conditions, tuber initiates early, but the sink is strong and the source is weak, leading to low incidence of stolon, high incidence of tuber death, and low number and weight of potato tuber per plant. Excessive nitrogen supply inhibits the development of stolons, delays the formation time of tubers, and reduces the number and weight of tubers. The supply of suitable nitrogen is conducive to the formation of high yield. The reasons may be that the tip of stolons expands early to form tubers, the incidence of tuber death is low, and the number and weight of tubers per plant increases. Previous researchers have done a lot of work on the regulation of potato tuber development regarding reasonable nitrogen supply, but due to different climatic factors, soil physicochemical properties, main varieties and production purposes, the threshold values are different either. These remain to be further explored. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of wuling capsules combine with tenofovir disoproxil fumarate tablets on oxidative stress, CD4+CD25+ regulatory T cells, serum matrix metalloproteinase-1 (MMP-1), matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in patients with chronic hepatitis B (CHB). Methods: 122 CHB patients who were admitted to the Infectious Diseases Hospital Affiliated to Soochow University from June 2021 to December 2022 were enrolled, patients were divided into control group (n=61, tenofovir disoproxil fumarate tablets) and study group (n=61, wuling capsules combined with tenofovir disoproxil fumarate tablets) by random number table method. The efficacy, oxidative stress indexes, CD4+CD25+ regulatory T cells, liver function indexes [total bilirubin (TBIL), alanine aminotransferase (ALT), glutamyl transpeptidase (GGT)], serum MMP-1, MMP-2, TIMP-1 levels and adverse reactions were compared between two groups. Results: The total clinical effective rate in study group was higher than that in control group(P<0.05). The malondialdehyde (MDA) decreased in two groups after treatment, and study group was lower than that of control group at the same time point. Superoxide dismutase (SOD) increased, and study group was higher than that of control group at the same time point(P<0.05). CD4+CD25+ regulatory T cells decreased in two groups after treatment, and study group was lower than that of control group at the same time point(P<0.05). MMP-1, MMP-2 and TIMP-1 decreased in two groups after treatment, and study group was lower than that of control group at the same time point(P<0.05). TBIL, ALT and GGT decreased in two groups after treatment, and study group was lower than that of control group at the same time point (P<0.05). There was no difference in the total incidence of adverse reactions between two groups (P>0.05). Conclusion: Wuling capsule combine with tenofovir disoproxil fumarate tablets in the treatment of CHB patients, which can effectively reduce the body's oxidative stress, regulate CD4+CD25+ regulatory T cells and serum MMP-1, MMP-2, TIMP-1 levels. [ABSTRACT FROM AUTHOR]

【Objective】Effects of rotation of patchouli [Pogostemon cablin（Blanco) Benth.]and mint（Mentha haplocalyx Briq.)and continuous cropping of patchouli on the quality and rhizosphere soil microecology of patchouli were studied, to provide the basis for alleviating the continuous cropping obstacle of patchouli and its application in production. 【Method】The cutting seedlings of patchouli and mint seedlings were used in the field experiment. There were three treatments: patchouli continuous cropping group（planting patchouli for two consecutive years), patchouli and mint crop rotation group（mint was planted in the first year and patchouli was planted in the second year), control group（no crop was planted in the first year, and patchouli was planted in the same field in the second year after harvest). The main agronomic traits, antioxidant enzyme activities in leaves, patchouli alcohol content, physical and chemical properties of rhizosphere soil, microbial quantity and enzyme activities were measured at different growth stages of patchouli. 【Result】When the patchouli plant had grown for 180 days, the main agronomic traits（plant height, stem diameter, number of primary branches, number of leaves, chlorophyll content, leaf area) and alcohol content of patchouli in rotation group were significantly higher than those in continuous cropping group（P＜0.05). The activities of peroxidase and superoxide dismutase of leaves in patchouli were respectively 54.23%（P＜0.05) and 115.71%（P＜0.05) higher in the rotational crop group compared with the continuous cropping group. Soil physical and chemical properties（pH, organic matter, available P, hydrolyzable N, available K) of patchouli rhizosphere in rotation group were significantly higher than those in continuous cropping group. The number of soil bacteria and actinomycetes in rotation group increased by 98.95%（P＜0.05) and 71.61%（P＜0.05), respectively. However, the number of soil fungi in the crop rotation group was reduced by 48.86%（P＜0.05) compared to the continuous crop group; The activities of soil peroxidase and urease in rotation group increased by 827.66%（P＜0.05) and 655.00%（P＜0.05) compared with the continuous cropping group, the activity of soil sucrase and polyphenol oxidase in rotation group was 44.49%（P＜0.05) and 28.99%（P＜0.05) lower than that in continuous cropping group. 【Conclusion】The agronomic traits, patchouli alcohol content and soil micro-ecological index of patchouli and mint rotation were better than those of patchouli continuous cropping. [ABSTRACT FROM AUTHOR]

BACKGROUND: Cartilage defects are one of the major clinical challenges faced by orthopedic surgeons. Tissue engineering is an interdisciplinary approach that combines knowledge of engineering and cell biology to provide new ideas and approaches for the repair of cartilage defects. OBJECTIVE: To prepare a multi-component composite scaffold based on silk fibroin, gelatin, and chitosan to screen for a three-dimensional porous scaffold suitable for cartilage regeneration by evaluating its physicochemical properties and biological performance. METHODS: Four groups of porous scaffolds were prepared by vacuum freeze-drying method using silk fibroin, gelatin and chitosan as the base materials, namely chitosan/gelatin scaffold, silk fibroin/chitosan scaffold, silk fibroin/gelatin scaffold and silk fibroin/chitosan/gelatin scaffold. The suitable cartilage scaffolds were screened by scanning electron microscopy, X-ray diffractometer, porosity, water absorption and swelling rate, biodegradation rate and mechanical property detection. Then cartilage scaffolds were co-cultured with chondrocytes isolated and extracted from patients with osteoarthritis. The feasibility of porous scaffolds for cartilage injury repair was evaluated in vitro by cell adhesion rate assay, cell live-dead staining and cell activity proliferation assay. RESULTS AND CONCLUSION: (1) All four groups of scaffolds had porous structures. The comprehensive physical performance test results showed that the silk fibroin/gelatin/chitosan scaffold was more in line with the requirements of cartilage defect repair. This scaffold had a pore size of (176.00±53.68) μm, the porosity of (80.15±2.57)%, and water absorption and swelling rate of (3 712±358)%. After immersion in PBS containing lysozyme for 28 days in vitro, the biodegradation rate was (46.87±3.25)%, and it had good mechanical properties. (2) Chondrocytes could adhere well on the silk fibroin/gelatin/chitosan scaffold, and the cell adhesion rate increased with time. CCK8 and live/dead cell double staining results showed that silk fibroin/gelatin/chitosan scaffold had good biocompatibility and low cytotoxicity. (3) The results showed that silk fibroin/gelatin/chitosan scaffold had a highly hydrated 3D structure, suitable pore size and porosity, good biodegradability and superior mechanical properties, which can provide a good reticular skeleton and microenvironment for nutrient transport and chondrocyte attachment and proliferation. [ABSTRACT FROM AUTHOR]

BACKGROUND: CXC motif chemokine 5 (CXCL5) is a neutrophil activating peptide derived from epithelial cells, which may be involved in arterial diseases. However, there is yet no report on the effect of CXCL5 in vascular calcification. OBJECTIVE: To explore the role of CXCL5 in the vascular calcification of carotid atherosclerosis (CAS). METHODS: (1) Cytological experiment: Mouse vascular smooth muscle cells (VSMCs) were divided into five groups: osteogenic medium group, Vector group (vector, blank plasmid transfected into VSMCs), CXCL5 group (CXCL5 plasmid transfected into VSMCs), si-NC group (CXCL5 negative control siRNA transfected into VSMCs), si-CXCL5 group (CXCL5 siRNA transfected into VSMCs), Vector+LY2157299 group and CXCL5+LY2157299 group (LY2157299 transferred into the cells 24 hours after cell transfection). Alizarin red staining, alkaline phosphatase staining, and calcium content determination were performed to evaluate the osteogenic differentiation level of VSMCs. (2) Animal experiment: Forty-eight ApoE-/- mice were randomly divided into four groups (n=12 per group): Con+siNC group, Con+si-CXCL5 group, CAS+si-NC group and CAS+si-CXCL5 group. Animal models were not prepared in the first two groups, in which si-NC or si-CXCL5 lentivirus was injected into the tail vein; carotid atherosclerosis models were made in the latter two groups, in which si-NC or si-CXCL5 lentivirus was injected into the tail vein. Von Kossa staining and immunohistochemical staining were used to evaluate carotid vascular calcification and the expression of CXCL5 and transforming growth factor-β receptor 1 (TGFBR1) in mice. RESULTS AND CONCLUSION: In the CXCL5 group, the protein level of runt-related transcription factor 2 (RUNX2) was up-regulated and the level of α-smooth muscle actin was down-regulated, in contrary to the findings in the si-CXCL5 group. In addition, CXCL5 overexpression upregulated the level of TGFBR1, while CXCL5 knockdown inhibited the level of TGFBR1. Compared with the Vector group, the intensity of alizarin red staining, alkaline phosphatase activity and calcium content in the CXCL5 group increased significantly (P < 0.05). Compared with the si-NC group, the intensity of alizarin red staining, alkaline phosphatase activity and calcium content in the si-CXCL5 group decreased significantly (P < 0.05). When LY2157299 inhibited TGFBR1 expression, the osteogenic differentiation of VSMCs induced by CXCL5 was reduced. Compared with the Con+si-NC group, the expression of CXCL5 protein in the carotid artery and calcification area in the CAS+si-NC group increased significantly (P < 0.05). Compared with the CAS+si-NC group, the expression of CXCL5 protein in the carotid artery and vascular calcification area in the CAS+si-CXCL5 group decreased significantly (P < 0.05). In addition, compared with the Con+si-NC group, the expression of RUNX2 protein in the carotid artery in the CAS+si-NC group increased significantly (P < 0.05), while the expression of α-smooth muscle actin protein decreased significantly (P < 0.05). Compared with the CAS+si-NC group, the expression of RUNX2 protein in the carotid artery in CAS+si-CXCL5 group decreased significantly (P < 0.05), while the expression of α-smooth muscle actin protein increased significantly (P < 0.05). In conclusion, CXCL5 can induce osteogenic transformation of VSMCs by activating the TGFBR1 pathway, and inhibition of CXCL5 expression is effective in improving carotid arterial calcification in CAS mice. [ABSTRACT FROM AUTHOR]

Objective To understand the concentration of formaldehyde pollution in indoor air of four types of public places in Shijiazhuang City, and to assess the chronic non 一 carcinogenic and carcinogenic risks of employees in various types of places. Methods Using the monitoring data of health hazards in public places, we analyzed the concentration levels of formaldehyde in the indoor air of swimming pools, barber stores, beauty stores, and hotels in Shijiazhuang City in 2021 - 2022, and evaluated the chronic non 一 cancer and cancer risks of formaldehyde for employees in the above four types of public places by adopting the classic,r four 一 step" health risk assessment model of the U. S. Environmental Protection Agency (US EPA). Results From 2021 to 2022, a total of 169 swimming pools, barber stores, beauty stores and hotels were randomly selected, with a total sample size of 485 formaldehyde tests, and the overall pass rate was 91.34%. The pass rate of formaldehyde concentration in the indoor air of swimming pools in the above four types of public places was 100% (161/161), 93. 10% (27/29) for barber stores, 90. 09% (20/22) for beauty stores and 86. 08% (235/273) for guesthouses(hotels), with statistically significant differences (x² = 24. 931, P < 0. 001); the mean value of the HQ of the chronic non 一 carcinogenic effect of formaldehyde for practitioners in swimming pools was less than 1, and that for practitioners in the other three types of public places was greater than 1, and swimming pools, Hairdressers, beauty stores, and hotels, the cancer risk values of formaldehyde for employees were 1. 90 X 10-5, 8, 19 X 10-5, 1. 13 X 10-4, and 5. 63 X 10-5, respectively, which were higher than the limit value (1 X 10 "6) set by the U.S. Environmental Protection Agency (US EPA). Conclusion Exposure to formaldehyde in the indoor air of swimming pools in Shijiazhuang City doesn't exceed the threshold for adverse reactions, and the chronic non - carcinogenic risk of formaldehyde for practitioners in this type of venue is low. There was a certain amount of chronic non 一 carcinogenic and carcinogenic risk for practitioners in barber stores, beauty stores, and guesthouses, and the risk value of formaldehyde for practitioners in the beauty category of venues is the highest, and it should be analyzed in further studies. [ABSTRACT FROM AUTHOR]

This study was to evaluate the effects of fish meal replaced by cottonseed protein hydrolysate and dietary supplementation of tannic acid on growth performance and intestinal health of channel catfish (Ictalurus punctatus). A basal diet with 10% fish meal was designed, and then cottonseed protein hydrolysate was used to replace 33.3%, 66.6%, and 100% of dietary fish meal, and 0.5 g/kg and 1 g/kg tannic acid were added to 100% replacement group to formulate six isonitrogenous diets (D1, D2, D3, D4, D5, D6). The six diets were fed to channel catfish with an average weight of (172.6±1.6) g for 67 days. The results showed that the final body weight and weight gain rate of D4, D5, and D6 groups were significantly lower than those of D1 group, while the feed coefficient of D4 and D6 groups was significantly higher than that of D1 group (P< 0.05). There were no significantly differences in survival, condition factor, viscerosomatic index, hepatosomatic index and proximate composition of muscle among all groups (P>0.05). Firmicutes, Bacteroidota, Proteobacteria and Fusobacteria were the dominant microbiome of hind-gut of channel catfish at phylum level. The relative abundance of Bacteroides in D4 group was significantly lower than that in D5 group (P<0.05), while the relative abundance of Proteobacteria in D4 group was significantly higher than that in D1, D2, and D5 groups (P<0.05). There was no significant difference in the histological morphology and microbial diversity in all groups (P>0.05) In summary, in a basal diet containing 10% fish meal, cottonseed protein hydrolysate could replace 66.6% of fish meal without negatively affecting on growth performance and intestinal health of channel catfish, and 0.5 g/kg tannic acid supplementation in no fish meal diet could effectively improve the intestinal microbiota composition of channel catfish, but had no effect on growth performance. [ABSTRACT FROM AUTHOR]

Objective To compare the safety and clinical efficacy of lesion removal combined with percutaneous pedicle screw fixation with classical posterior lesion removal in the treatment of lumbar brucelli spondylitis(LBS)by unilateral biportal endoscopic technique with transforaminal lumbar interbody fusion(UBE-LIF)technique. Methods The clinical data of 32 patients with LBS admitted by the Department of Spine and Orthopedics of Gansu Provincial Hospital of Traditional Chinese Medicine from January 2020 to January 2022 were retrospectively analyzed, and the clinical data of the 32 LBS patients were divided into 15 cases in the UBE-LIF group and 17 cases in the posterior group. The general data, surgery-related indexes, and postoperative pathological HE staining of the two groups were recorded and analyzed. The patients' clinical recovery was assessed according to their erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP), low back pain visual analogue score(VAS), Japanese Orthopaedic Association(JOA)score, and Oswestry Dysfunction Index(ODI)preoperative, 1 week after surgery, 1, 3, 6 months and 1 year after surgery. Lumbar lordosis angle(LL)and intervertebral space height(DH)were measured by imaging before surgery and at the last follow-up, and intervertebral bone graft fusion was assessed using Suk grading criteria. Results Both groups successfully completed the operation and no serious postoperative complications occurred. There were no significant differences in gender, age, surgical segment, operation time, preoperative ESR and CRP, preoperative VAS, JOA score and ODI index, preoperative LL and DH(P>0.05). The intraoperative blood loss, postoperative drainage, postoperative getting out of bed, and postoperative hospital stay in UBE-LIF group were significantly lower than those in the posterior group(P<0.001). Pathological examination of diseased tissues was performed during surgery, all of which was consistent with brucellosis changes. Patients in both groups were followed up for 12-18 months, with an average of 14.8 months. The VAS, JOA score, and ODI index at all postoperative time points in the two groups were significantly improved compared with the preoperative period(P<0.05). The difference between the two groups was significantly greater than that in the postoperative group: VAS score was lower in UBE-LIF group than in the posterior group(P<0.01), CRP in both groups was higher than that in the preoperative group, and the elevation level was significantly lower in UBE-LIF group than in the posterior group(P<0.001). There was no significant difference in ESR between the two groups compared with that before surgery(P>0.05). There were no significant differences in VAS, JOA score, ODI index, CRP or ESR between the remaining time points after surgery(P>0.05). At the last follow-up, imaging examination showed that the overall fusion rate of intervertebral bone graft in UBE-LIF group was 93.3% and 94.1% in the posterior group, without significant difference(X²=0.246, P=0.884). LL and DH were significantly improved in both groups compared with preoperative ones(P<0.01), and the two groups did not significantly differ before and after surgery(P>0.05). Conclusion Both surgical treatments for LBS are safe effect. Compared with posterior lesion removal bone graft fusion internal fixation, UBE-LIF technology combined with percutaneous pedicle screw internal fixation has the advantages of clear intraoperative vision, less blood loss, faster early postoperative recovery, and shorter postoperative hospital stay, and thus is a feasible surgical method for the minimally invasive treatment of LBS. [ABSTRACT FROM AUTHOR]

Objective : To discuss the improvement effect of curcumin combined with fecal bacteria transplantation on the mice with dextran sulfate sodium (DSS) -induced ulcerative colitis (UC), and to clarify the related mechanism. Methods : Fifty mice were randomly divided into control, model, curcumin, fecal bacteria transplantation, and combination groups. Except for the mice in control group (given distilled water), the mice in the other groups were given distilled water containing 2% DSS to establish the UC models. The mice in curcumin group were gavaged with 0. 4 mL of 60 mg·kg－1 curcumin solution once per day for 10 d; the mice in fecal bacteria transplantation group underwent enema with 0. 2 mL of fecal bacteria suspension once per day for 10 d; the mice in combination group received the enema of 0. 2 mL fecal bacteria suspension and gavaged with 0. 4 mL of 60 mg·kg－1 curcumin solution. At the end of the experiment, the disease activity index (DAI) and colon macroscopic damage index (CDMI) of the mice in various groups were calculated; the morphology of colon tissue of the mice in various groups was detected by HE staining; the levels of interleukin (IL) -1 β, tumor necrosis factor- α (TNF-α), IL-4, and IL-10 in colon tissue of the mice in various groups were detected by enzyme-linked immunosorbent assay (ELISA) method; the expression levels of occludin and zonula occludens-1 (ZO-1) mRNA and proteins in colon tissue of the mice in various groups were detected by real-time fluorescence quantitative (RT-qPCR) and Western blotting methods. Results : The intestinal mucosal epithelial structure of the mice in control group was intact and continuous with regular glandular arrangement and without inflammatory cell infiltration or ulceration; the intestinal mucosal epithelial structure of the mice in model group exhibited loss of colonic mucosal epithelium, disordered glandular arrangement, reduced goblet cells, congestion and edema in mucosal and submucosal layers, and extensive infiltration of inflammatory cells with widespread small ulcers; the intestinal mucosal epithelial structure of the mice in curcumin, fecal bacteria transplantation, and combination groups exhibited relatively intact colonic mucosal epithelial structures with reduced inflammatory cell infiltration and ameliorated mucosal and submucosal congestion and edema. Compared with control group, the DAI and CDMI of the mice in model group were increased (P<0. 05), the levels of IL-1β and TNF-α were increased (P<0. 05), the levels of IL-4 and IL-10 were decreased (P<0. 05), and the expression levels of occludin and ZO-1 mRNA and proteins were decreased (P<0. 05) ; compared with model group, the DAI and CDMI of the mice in curcumin, fecal bacteria transplantation, and combination groups were decreased (P<0. 05), the levels of IL-1β and TNF-α were decreased (P<0. 05), the levels of IL-4 and IL-10 were increased (P<0. 05), and the expression levels of occludin and ZO-1 mRNA and proteins were increased (P<0. 05) . Compared with curcumin group and fecal bacteria transplantation group，the DAI and CDMI of the mice in combination group were decreased (P<0. 05), the levels of IL-1β and TNF-α were decreased (P<0. 05), the levels of IL-4 and IL-10 were increased (P<0. 05), and the expression levels of occludin and ZO-1 mRNA and proteins were increased (P< 0. 05) . Conclusion : Curcumin combined with fecal bacteria transplantation can ameliorate the pathological damage in colonic tissue of the UC mice, inhibit the secretion of inflammatory factors, and promote the repayment of infesting mucosa. [ABSTRACT FROM AUTHOR]

With the emergence of OpenAI's ChatGPT, generative artificial intelligence has demonstrated its profound potential to develop. However, the problems about its unclear technologically ethical standards, which arise from the algorithmic rules, have ignited intense global discussions and apprehensions. Therefore, "being responsible" has become a pivotal demand for its development. Nonetheless, nowadays the existing documents discussing the regulation and governance of artificial intelligence from a "responsible" perspective are inadequate compared to the technological advancements themselves. In particular, there is a lack of profound research into the triggering mechanisms of the AIGC (AI-generated content) technology ethical crisis, as well as the formulation of deep-level investigations into "responsible" AI guidelines and regulatory frameworks. This article primarily adopts an approach that involves analyzing policies and data released by the Artificial Intelligence and Economic Society Research Center of the China Academy of Information and Communications Research, the official websites of OpenAI, the EuropeanCommission, and others. By drawing inspiration from the latest research achievements in "responsible" artificial intelligence in the journal Nature, this article explores and uncovers the legislative efforts made by governments worldwide related to "responsibility" in artificial intelligence, scholarly research on the topic, and the latest governance practices implemented by AI enterprises. This research investigates the current state of "responsible" artificial intelligence, its regulatory domains, and the adopted governance measures. The research reveals that the ethical crisis of "unintelligibility, uncontrollability, unreliability, and unsustainability" triggered by AIGC is not only harming humanity but also hindering the advancement of AI technology itself. Thus, it is imperative for humans to regulate and govern artificial intelligence responsibly for the benefit of humanity. As of now, there is a basic consensus among governments worldwide, the academia, and global AI enterprises on the development of responsible artificial intelligence, which is to create a practical foundation for the responsible application of AI to humanity. In comparison to previous literature, this article extends the discourse in two main aspects: firstly, it explores the triggering mechanisms of the AIGC technology ethical crisis, mainly including low algorithmic operational transparency, which will lead to " misunderstanding"; a lack of subjective goodwill, which will trigger "uncontrollability"; Al illusions, which will cause security "unreliability", and the absence of established human- machine partnerships, which will invite "unsustainability". Secondly, in response to the ethical crisis of "misunderstanding," "uncontrollability," "unreliability," and "unsustainability," the article proposes targeted approaches for academia, government, AI enterprises, and users to address these issues. These include promoting academic research in interpretability from a "technology responsibility" perspective, ethical agreements and regulations with a "social responsibility" approach, enterprise autonomy from a "user responsibility" perspective, and enhancing algorithmic literacy with a "self-responsibility" approach, respectively. The core content of this article unveils the triggering mechanisms underlying the AIGC technology ethical crisis and proposes targeted governance strategies. Particularly, the detailed research analyses of foreign legislation related to generative artificial intelligence and AI enterprise autonomy might provide useful insights for China's legislation and autonomous corporate development in this field. Additionally, the study of "responsible" artificial intelligence aims to stimulate academic exchange and embrace intellectual collisions while humbly seeking guidance from relevant experts in this field. [ABSTRACT FROM AUTHOR]

With persistent progress in donor-recipient evaluation criteria, organ procurement and preservation regimens and surgical techniques, the incidence of vascular complication after kidney transplantation has been declined, whereas it is still one of the most severe surgical complications of kidney transplantation, which may lead to graft loss and recipient death, and seriously affect the efficacy of kidney transplantation. Therefore, the occurrence, clinical manifestations, diagnosis and treatment strategies of common vascular complications after kidney transplantation, including vascular stenosis, arterial dissection, pseudoaneurysm, vascular rupture and thrombosis were reviewed in this article. In combination with the incidence, diagnosis and treatment of vascular complications after kidney transplantation in the First Affiliated Hospital of Xi'an Jiaotong University, diagnosis and treatment strategies for common vascular complications after kidney transplantation were summarized, aiming to provide reference for clinical diagnosis and treatment of vascular complications after kidney transplantation, lower the incidence of vascular complications, and improve clinical efficacy of kidney transplantation and survival rate of recipients. [ABSTRACT FROM AUTHOR]

In 2020, a 73-year-old woman underwent posterior hepatic segment resection and cholecystectomy for hepatocellular carcinoma. Histopathological findings confirmed the diagnosis, and the hepatocellular carcinoma was subsequently staged as pT3N0M0. In January 2022, blood tests revealed an increase in the level of protein induced by vitamin K absence or antagonist- Ⅱ (PIVKA-II), and a follow-up computed tomography (CT) scan in April revealed a tumor, 16 mm in diameter, on the dorsal side of her right kidney. Positron emission tomography-CT (PET-CT) revealed an accumulation of fluorodeoxyglucose, with a standardized uptake value maximum (SUVmax) of 3.6, at the same site, and the patient was diagnosed with retroperitoneal metastasis of hepatocellular carcinoma, and was referred to our department for resection. Since the tumor was located in the abdominal wall, specifically in the perinephric adipose tissue, and since some degree of difficulty was expected in visually identifying the tumor during surgery, preoperative CT-guided marking was performed. Following marking, the patient underwent retroperitoneal tumorectomy. During surgery, as expected, it was difficult to visually identify the tumor ; however, by using the thread and metal hook markings, we were able to locate the tumor and resect it. One week after the surgery, the PIVKA-II level was measured and found to have decreased to within the normal range. The pathological diagnosis was retroperitoneal metastasis of hepatocellular carcinoma. We suggest that preoperative marking is useful for small-diameter tumors and in cases where it is difficult to identify the extent of the resection ; however, few such cases have been reported in the field of urology. We encountered a case in which preoperative CT-guided marking was carried out for a small-diameter metastatic retroperitoneal tumor, which was successfully resected. [ABSTRACT FROM AUTHOR]

Objective: To study the regulation and mechanism of Asperosaponin Ⅵ on polarization of M1/M2 macrophages. Methods: MTT assay was used to detect the effects of Asperosaponin Ⅵ on RAW264.7 cell viability. The levels of TNF-α and IL-6 in supernatant of RAW264.7 cells induced by lipopolysaccharide (LPS) were determined by ELISA. The content of nitric oxide (NO) in supernatant of RAW264.7 cells induced by LPS was determined by Griess method. The gene expression levels of TNF-α, IL-6, arginase-1（Arg-1), heme oxygenase-1（HO-1) and suppressor of cytokine signaling protein-2（SOCS2) were detected by fluorescence quantitative PCR. Western blot was used to detect the expression levels of iNOS and p-p65 protein. Results: In LPS induced RAW264.7 cells, Asperosaponin Ⅵ inhibited protein or gene expression levels of TNF-α, IL-6, iNOS and p-p65, and increased HO1 gene expression. Asperosaponin Ⅵ inhibited NO secretion in RAW264.7 cells induced by LPS. Asperosaponin Ⅵ increased the gene expression levels of M2 macrophage markers Arg1 and SOCS2 induced by IL-4. Conclusion: Asperosaponin Ⅵ inhibited RAW264.7 macrophage polarization to M1 type and promote it polarization to M2 type, which can play its anti-inflammatory and immunomodulatory role by regulating M1/M2 macrophage polarization. [ABSTRACT FROM AUTHOR]

Long non-coding RNAs(lncRNAs) can be involved in regulating gene expression through multiple interactions with DNA, RNA or proteins. Studies have shown that lncRNAs not only regulate innate immune response, but also regulate immune cell development and adaptive immunity. According to recent reports, a number of lncRNAs play a role in the pathogenesis of immunemediated inflammatory diseases, including systemic lupus erythematosus(SLE), and may become a diagnostic marker and prognostic reference for diseases. This paper summarizes the research progress of lncRNAs in SLE, with the hope of providing more new ideas and methods for the study of SLE. [ABSTRACT FROM AUTHOR]

3,3,4,4 -Tetramethyl-diphenylmethane (TMDM) is a key raw material for the synthesis of ketone-anhydride type polyimide, and understanding its solubility behavior is the first step toward the successful development of crystallization processes. The solubility data of TMDM in selected solvents of ethanol, isopropanol, isobutanol, n-propanol and n-butanol were first determined by dynamic method at 273. 15 to 293. 15 K under atmospheric pressure. The results show that the solubility of TMDM in the above solvents increases with the temperature, among which the solubility in n-butanol is the largest and that in ethanol is the smallest. The solubility data were correlated by Apelblat equation, Van t Hoff equation, Wilson model and 入h equation, and the fitting effect of Apelblat equation was the best. Moreover, the dissolution enthalpy, dissolution entropy and Gibbs free energy were calculated with Vant Hoff equation, and the results show that the dissolution process is a non-spontaneous endothermic process which is mainly enthalpy-driven. [ABSTRACT FROM AUTHOR]

探讨多发伤儿童肝功能损害的病因和临床特点，为早期病因诊断和治疗提供理论依据。方法：选取南京医科 大学附属儿童医院2016年1月—2022 年12月多发伤住院儿童216例为研究对象，收集临床资料，检测治疗期间静脉血全套生 化，结合伤后影像学检查（腹部 CT 和/或 B 超），进行统计分析。结果：①216 例多发伤儿童中，发生肝功能损害共 74 例 （34.26%）；②按肝功能损害原因分类，肝脏挫伤 25 例（33.78%），其他原因包括失血性休克 21 例（28.38%），呼吸衰竭 16 例 （21.62%），药物性肝功能损害3例（4.05%），心肺复苏后肝功能损伤3例（4.05%），多种原因所致肝功能损害6例（8.11%）；③多 发伤儿童肝功能损害治疗效果明显。结论：肝功能损害在多发伤儿童中较为常见，除肝脏直接挫伤外，各种病因引起的肝脏缺 血缺氧也是常见原因。通过及时诊断和治疗，多发伤儿童肝功能损害恢复良好。 [ABSTRACT FROM AUTHOR]

The function of protein is crucial for understanding the mechanisms of cellular and biological activities, as well as for studying the mechanisms of diseases. Traditional experimental and sequence alignment methods are insufficient to support large-scale protein functional annotation when in the face of the rapid growth of sequence databases. For this situation, this paper proposed EGnet（Evolutionary Graph Network） model, which utilized the protein pre-training language model ESM2 and One-hot encoding to obtain the protein sequence encoding. The model integrated the coevolutionary information between residues, including PI（Paired Interaction） and SPI（Strong Paired Interaction）, through sequence self-attention and physical calculations. Subsequently, the two types of coevolutionary information and the sequence encoding used in inputs for a multi-layered cascaded graph convolutional network to learn the node features of the sequence encoding and achieve end-to-end protein function prediction. Compared with earlier methods, EGnet achieved better performance on the EC（Enzyme Commission） category labels in the ENZYME database, which reached 0.89 in the F-score and 0.91 in the AUPR. The results indicate that EGnet can achieve good performance by using only a single sequence to predict protein function, providing a rapid and effective method for protein function annotation. [ABSTRACT FROM AUTHOR]

A miniaturized broadband tri - polarized antenna for 5G mobile communication is proposed in this study. A pair of hollow annular orthogonal dipoles is adopted as the horizontal dual polarization of the antenna, mean-while a planar rectangular frame equivalent to a monopole is constructed as the vertical polarization of the antenna, which is fed by a microstrip integrated balun and the four - equivalent power dividing microstrip lines, respectively. The proper choice of the feeding method and the ingenious design of the pointed cone planar rectangular frame achieve the broadband characteristics of the antenna, and the integrated structure layout realizes the miniaturization of the antenna. The antenna structure is compact with a volume of 0.27λ min 0.27 ×λmin ×0.17 λmin, where Amin is the free space wavelength of the lowest frequency. To verify the design, the prototype antenna is manufactured and measured, and the measured results agree well with the simulation. The measurement results show that the antenna impedance bandwidth is 3.00~4.48 GHz(voltage standing wave ratio is less than 2), the relative bandwidth is 39.6%, and the isolation degree between the three ports is greater than 27 dB. In addition, in the entire frequency band, the horizontal polarization gain of the antenna is greater than 6 dB, the vertical polarization gain is greater than 3 dB, and the antenna has stable pattern characteristics and good orientation, indicating that the antenna has greater practical value in 5G small - pitch arrays and narrow spaces. [ABSTRACT FROM AUTHOR]

[Objective] The aims of this study are to explore the growth adaptation strategies of different life-types of plants to the habitats in the Yanhe River Basin, and to provide theoretical basis and practical guidance for understanding the mechanisms of plant adaptation to the environment and the selection of species for vegetation restoration in this basin. [Methods] Using the Yanhe River Basin in the Loess Hills region as the study area, we selected three plant life types: trees, shrubs and herbs, six plant functional traits related to resource acquisition capacity were investigated. ANOVA, linear regression and redundancy analysis were applied to investigate the adaptation strategies and mechanisms of different life types of plants to the environment in the Yanhe River Basin. [Results] The specific leaf area, specific root length, leaf tissue density, root tissue density, leaf nitrogen content, and root nitrogen content of different life types of plants in the Yanhe River Basin were significantly different. Water was the limiting factor for plant survival in the Yanhe River Basin. [Conclusion] To adapt to the habitats of the Yanhe River basin, herbaceous plants adopted a ‘fast investment-gain’ type（acquisition type） strategy, while shrubs and trees adopted a ‘slow investment-gain’ type（conservative type） strategy. [ABSTRACT FROM AUTHOR]

Objective To explore the cluster analysis of TCM syndromes in patients with type 2 diabetic nephropathy ( T2DN) and its relationship withdisease staging. Methods A total of 170 patients with T2DN admit‐ tedto our hospital from March 2020 to October 2022 were selected. The general dataof TCM syndromes of T2DN patients, and the distribution of TCM syndromes were observed, including the original TCM syndrome and the concurrent TCM syndrome. The cluster diagram was drawnby using systematic cluster analysis. The correspondence between TCM syndrome types and disease severity was analyzed by simple correspondence. Results The main TCM syndromes of early T2 DN, clinical T2 DN and end-stage renal disease ( ESRD) were qi and yin deficiency with blood stasis syndrome ( 38.46%), qi stagnation and phlegm stasis syndrome ( 37.88%), qi stagnation and phlegm stasis syndrome ( 50.00%) . The different positions of the cluster diagram were intercepted, and the syndrome types were different. Among them, the D-point interception was divided into five syndromes： liver and kidney yin syndrome, heart and kidney deficiency syndrome, liver and stomach fire syndrome, qi and yin deficiency with stasis syndrome and qi stagnation and phlegm stasis syndrome. Among 170 patients with T2DN, there were 40 cases ( 23.53%) of liver and kidney yin syndrome, 26 cases ( 15.29%) of heart and kidney deficiency syndrome, 29 cases ( 17.06%) of liver and stomach fire syndrome, 20 cases ( 11.76%) of qi and yin deficiency with blood stasis syndrome, and 55 cases ( 32.35%) of qi stagnation and phlegm stasis syndrome. In the middle of the two-dimensional projection, qi and yin deficiency with blood stasis syndrome and qi stagnation and phlegm and blood stasis syndrome were not biased towards a certain grade of T2 DN lesion degree； the liver-stomach fire syndrome was biased towards stage V, the heart-kidney deficiency syndrome was biased towards stage Ⅳ, and the liver-kidney yin syndrome was biased towards stage Ⅰ-Ⅲ. Conclusion The basic TCM syndromes of T2 DN patients were liver and kidney yin, heart and kidney deficiency, liver and stomach fire, qi and yin deficiency with blood stasis and qi stagnation and phlegm and blood stasis. With the development of T2DN, TCM syndromes gradually changed from liver and kidney yin to heart and kidney deficiency to liver and stomach fire, and qi and yin deficiency with blood stasis and qi stagnation and phlegm stasis accompanied T2DN patients at all stages. [ABSTRACT FROM AUTHOR]

[Objective] To establish a rapid detection method for heavy metal elements in Radix Isatidis. [Method] The content of Pb, Cd, As, Hg and Cu in Radix Isatidis from different regions was rapidly determined using inductively coupled plasma mass spectrometry (ICP-MS). The differences in five heavy metal elements in Radix Isatidis from different regions such as Hebei, Henan and Anhui were investigated, and the quality differences of Radix Isatidis from different regions were evaluated using principal component analysis and cluster analysis.[Result]There was a good linear relationship between the five heavy metals and harmful elements in their respective ranges (R²≥0.999 6). The average recoveries were 97.63%-99.96%, RSD was 1.43%-3.83%. In 30 batches of samples, 86.67% of the samples had Cd content exceeding the standard, 26.67% of the samples had Cu content exceeding the standard, 66.67% of the samples had no Hg detected, and Hg, Pb, As in the collected samples did not exceed the standard. Two components were extracted by principal component analysis, with a cumulative contribution rate of 72.53%. Pb and Cd contributed significantly to the quality evaluation of Radix Isatidis. According to the comprehensive score, the quality of Radix Isatidis collected from Anguo, Hebei was good; cluster analysis showed that there were significant differences in the content of test indicators in different habitats. [Conclusion] ICP-MS can quickly and accurately determine the contents of five kinds of heavy metals in Radix Isatidis. This method is efficient and accurate, and can be used for the quality control of heavy metal elements in Radix Isatidis. [ABSTRACT FROM AUTHOR]

Treatment of bone defects remains a complicated clinical problem. Changes of immune response in local bone microenvironment following biomaterial implantation is key factor that determines success or not. However, there are many defects in immune regulation of biomaterials at present, failure to induce immune microenvironment that is conducive to bone defect repair has become a bottleneck restricting the development of biomaterials and limiting their widespread use. Therefore, it is necessary to deeply explore the changes of immune response induced by biomaterials in bone microenvironment. This article reviews the research progress of the interaction mechanism between immune cells and cytokines that are mainly involved in immune response mediated by bone repair biomaterials in the microenvironment. [ABSTRACT FROM AUTHOR]

Objective: To investigate the role of signal transduction and transcriptional activator 3(STAT3) gene in regulating the proliferation, invasion and migration of EC106 cells of esophageal cancer and its related mechanisms. Methods: STAT3 expression in EC106 cells of esophageal cancer was interfered by STAT3 shRNA lentiviral vectors and STAT3 overexpression lentiviral vectors. The cells were divided into control group, silent group and overexpressed group. CCK-8 method was used to detect the differences in cell proliferation, cell cycle changes were observed by flow cytometry, cell migration and invasion ability were evaluated by cell scratch assay and Transwell assay. RT-PCR was used to detect the mRNA expression levels of STAT3，P13K and Akt, and Western blot was used to detect the protein expression levels of Ki67, PCNA, E-cadherin and Vimentin. Results: Compared with the control group, the cell proliferation in the silent group was significantly decreased(P<0.05), while the cell proliferation in the overexpressed group was increased. Flow cytometry showed that compared with the control group, the cell cycle of the silenced group was blocked in the G0/G1 phase(P<0.05), while the cell cycle of the overexpressed group was increased in the S phase. In addition, the results of cell scratch test showed that the migration ability of cells in the silencing group was significantly decreased(P<0.05), while the migration ability of cells in the overexpressed group was enhanced. Transwell test showed that the invasion ability of cells in the silencing group was significantly weakened(P<0.05), while the invasion ability of cells in the overexpressed group was enhanced. The results of RT-PCR showed that compared with the control group, the mRNA contents of STAT3, P13K and Akt in the silenced group were signifi⁃ cantly decreased(P<0.05), while the mRNA contents of STAT3, P13K and Akt in the overexpressed group were significantly increased. The results of Western blot analysis showed that compared with the control group, the relative expression levels of Ki67, PCNA and Vimentin proteins in the silent group were significantly decreased, the expression of E-cadherin was significantly increased, and the relative expressions of Ki67, PCNA and Vimentin proteins in the overexpressed group were increased. E-cadherin expression was significantly decreased(P<0.05). Conclusion: STAT3 plays an important role in the survival of EC106 cells of esopha⁃ geal cancer. After silencing the expression of STAT3, the expressions of P13K and Akt are down-regulated, the cell cycle process is blocked, and cell proliferation, migration and invasion are inhibited. [ABSTRACT FROM AUTHOR]

Objective: To summarize the experiences of diagnosing and treating abdominal compartment syndrome (ACS) after patch repairing of neonatal congenital diaphragmatic hernia (CDH) under extracorporeal membrane oxygenation (ECMO).Methods: Retrospective reviews were conducted for the clinical data of ACS neonates due to CDH undergoing patch repairing under ECMO. Management and surgical procedure of ACS were systematically summarized. The databases of PubMed, Web of Science, Wanfang, China Academic Journals (CAJ) and China National Knowledge Infrastructure (CNKI) were searched with such keywords as "congenital diaphragmatic hernia", "extracorporeal membrane oxygenation" and "abdominal compartment syndrome" . Duplicate literatures were excluded and managements of ACS after patch repairing of neonatal CDH under ECMO summarized. Results: One fetus with left-side CDH ultrasonically detected in second trimester was diagnosed as severe pulmonary hypoplasia. He was transferred immediately into our unit after a delivery by cesarean section at 39+ 6 weeks. ECMO support was provided after 19-hour mechanical ventilation and laparotomy patch repair of CDH was performed at 2 days post-birth. ACS was detected and treated with decompressive laparotomy (DL) at 4 days after repairing CDH. And a wound protector was utilized for keeping abdominal open during DL.ECMO was withdrawn at Day 3 and abdominal closure occurred at Day 5 post-DL. He was discharged at Day 38 post-birth. No recurrence occurred during a follow-up period of 4 months. A total of 16 English literature reports were reviewed. Four reports described 6 cases of CDH with postoperative ACS and 4 of them underwent DL. While another 12 reports examined 47 cases ACS under ECMO support and 37 of them underwent DL. Conclusions: DL is effective for ACS during patch repair of neonatal CDH under ECMO. And wound protector is recommended for DL in neonates. [ABSTRACT FROM AUTHOR]

To explore the relationship between the development level and connectivity of large-scale water systems, we focused on China′s water resource zones as the fundamental unit. To calculate the box dimension of each primary water resource zone, the fractal theory was employed, while multiple indicators such as the tributary development coefficient ratio of tributaries were selected to comprehensively characterize the developmental level of the water systems. Besides, the graph theory was used to quantify the connectivity of water systems at the primary water resource zone level under various conditions, including watershed decomposition, optimization of large lakes, and large-scale water diversion projects. Multiple indicators, including water system loop degree, were utilized to evaluate the connectivity of the water systems. Moreover, statistical methods were employed to investigate the intrinsic relationship between indicators of water system development and connectivity. The results demonstrated that the box dimensions of China′s top ten water resource zones range from 1. 1 to 1. 6. These zones were categorized into three levels, namely mature, relatively mature, and immature. By enhancing the graph models of each water resource zone, we could achieve a more accurate representation of the complexity and detailed characteristics of the water systems and thus could improve the precision of connectivity calculations. The correlation analysis revealed an overall positive correlation between the indicators of water system development and connectivity. Our research findings contribute to a quantitative description of the water system characteristics and connectivity in China′s water resource zones, providing valuable insights into the optimization of water resource allocation and management operations. [ABSTRACT FROM AUTHOR]

Using PHF-LSM (permeability-based hydraulic fracture-level set method) hydraulic fracturing calculation model, a rock material model with joint distribution is established. The correctness of the model is verified by comparing the geometric characteristics of fractures and the theoretical solution of induced stress with the simulation result. On this basis, the influence of the presence of joints on the stress shadow effect of hydraulic fractures is analyzed. The simulation results indicate that; the displacement difference of the outermost node in the equivalent fracture region should be used as the equivalent fracture opening in the PHF model based on the dispersion fracture model; the existence of joints will affect the change of water pressure in the process of fracture water injection, and will increase the equivalent fractures opening; a larger joint incidence angle and a smaller joint height from the water injection point will produce greater induced stress, and change the direction of the minimum principal stress, resulting in a stronger stress shadow effect and enhanced fracture deflection. [ABSTRACT FROM AUTHOR]

Total articular cartilage defects are usually accompanied by subchondral bone damage, and tissue engineering, as an interdisciplinary technique combining engineering and cell biology, provides new ideas and approaches for the repair of total cartilage defects. In this study, we developed a new approach for the repair of total cartilage defects by using silk fibroin (SF), gelatin (Gel), chitosan (CS) and hydroxyapatite (Hap) as the base materials to meet the needs of osteochondral extracellular matrix (ECM) and osteogenic-chondrogenic bipartite differentiation requirements. Five groups of SF-CS-Gel-nHap porous scaffolds (Hap-1%, Hap-2%, Hap-3%, Hap-4% and Hap-5%) without concentration gradient were prepared by vacuum freeze-drying and chemical cross-linking by adding different contents of hydroxyapatite to the co-blended solution of silk protein, chitosan and gelatin. The 3D porous composite scaffolds with superior physicochemical properties were screened by scanning electron microscopy, X-ray diffractometry (XRD), and the study of porosity, water absorption and swelling, biodegradation rates and mechanical properties. The scaffolds were then co-cultured with chondrocytes isolated and extracted from patients with osteoarthritis. The biological properties of the porous scaffolds were evaluated by cell adhesion rate determination, cell live-dead staining and CCK-8 cell activity proliferation assay to explore the feasibility of their use for repairing total cartilage defects. All five groups of scaffolds had porous structures, and the water absorption swelling and porosity of SF-CS-Gel-nHap porous scaffold decreased with increasing Hap content in the scaffold, while the biodegradation rate gradually slowed down with increasing Hap content. The SF-CS-Gel-1%Hap scaffold had the highest water absorption and swelling rate and porosity of 1 466%±179% and 87. 25%±2. 28%, respectively, but it had the fastest and least stable degradation and poor mechanical properties. SF-CS-Gel-2%Hap scaffold had a pore size structure of (212. 89±62. 22) μm, a porosity of 76. 52%±2. 31%, good water absorption and swelling rate of 1 286%±114%, and a biodegradation rate of 37. 09%±1. 41%. The physicochemical properties of SF-CS-Gel-2%Hap scaffold were more in line with the requirements of full-layered cartilage defect repair. During its co-culture with chondrocytes isolated and extracted from osteoarthritis patients, the SF-CS-Gel-2%Hap scaffold showed better bioactivity, i. e. good cell adhesion and proliferation properties, and the results of CCK-8 proliferation assay and live/dead cell double-staining assay showed that the porous scaffold had good biocompatibility and low cytotoxicity. The results of this experiment show that the SF-CS-Gel-2%Hap porous composite scaffold prepared based on gelatin, chitosan, silk fibroin and nano-hydroxyapatite can not only mimic the ECM of natural bone cartilage, but also has good biocompatibility and can provide a good reticular skeleton for nutrient transport and cell adhesion, proliferation and stereogenesis, providing a new option for the treatment of total cartilage defects. [ABSTRACT FROM AUTHOR]

BACKGROUND: For young patients with proximal lesions of long head of biceps tendons with high requirements for upper limb movement, the commonly tendon fixation includes interface extrusion screw fixation and suture anchor ligation fixation. At present, there are few clinical reports and no conclusion on the comparison of the clinical efficacy of the two. OBJECTIVE: To compare the clinical efficacy of proximal lesions of long head of biceps tendons by interface extrusion screw fixation and suture anchor ligation fixation in arthroscopy. METHODS: Totally 52 patients with proximal lesions of long head of biceps tendons treated in Nanchang Hongdu Hospital of TCM from January 2019 to December 2020 were enrolled and randomly divided into interface extrusion screw group (n=29) and suture screw group (n=23). The patients in both groups were subjected to interface extrusion screw fixation and suture anchor ligation fixation in arthroscopy, respectively. Before, 1, 3, 6, and 12 months after operation, and during last follow-up, shoulder visual analog scale score, the American shoulder and elbow surgeons score, and range of motion in anterior flexion of shoulder and internal and external rotation at elbow flexion 90° were compared between the two groups. Elbow flexion muscle strength, reoperation rate and complication rate (Popeye sign) were compared between the two groups at the last follow-up. RESULTS AND CONCLUSION: The visual analog scale scores, the American shoulder and elbow surgeons score and shoulder range of motion in anterior flexion of shoulder and internal and external rotation at elbow flexion 90° were significantly improved after operation compared with those before operation in both groups (P < 0.05). There were no significant differences in visual analog scale scores, the American shoulder and elbow surgeons score and shoulder range of motion in anterior flexion of shoulder and internal and external rotation at elbow flexion 90° between the two groups before and at various time points after operation (P > 0.05). At the last follow-up, the elbow flexion muscle strength of the two groups reached above grade IV, and the results showed no significant difference. Popeye syndrome occurred in the interface extrusion screw group (14%) and reoperation was performed (7%). In the suture screw group, the incidence of Popeye sign was 4.3% and the reoperation rate was 0%. The incidence of Popeye sign and the reoperation rate were not significantly different between the two groups (P > 0.05). For the proximal lesion of long head of biceps tendons, both the interface extrusion screw fixation and the suture anchor ligation fixation in the arthroscopy can effectively relieve shoulder pain and improve shoulder function within one year and the clinical effects of the two methods are equivalent. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship between re-employment and mortality risk of the elderly under the basic national situation of population aging. Methods Based on the survey data of Chinese Longitudinal Healthy Longevity Survey (CLHLS 2008-2018), a joint model of propensity score matching and time-dependent Cox risk regression were constructed to explore the impact of elderly employment on the mortality risk. Results The re -employment of the retired elderly could reduce the mortality risk by 17.9%. In the subgroup analysis, the re -employment of the elderly with advanced age, low education level, and poor economic status could reduce the mortality risk, both in men and women with no significant difference in the health effects of re-employment among different gender groups. Conclusion It is recommended that properly encouraging the re -employment of the elderly can alleviate the pressure of labor market, reduce the mortality risk of the retired elderly, and promote the realization of the strategic goal of healthy aging. [ABSTRACT FROM AUTHOR]