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In Japan’s super-aged society, many dental patients have underlying systemic diseases of the circulatory, respiratory, and endocrine systems. Acute exacerbations of these underlying diseases are often observed before, during, or after dental treatment. Even young people with no systemic diseases may develop vasovagal reflex and hyperventilation syndrome as a result of the stress, anxiety, and pain associated with dental treatment. Dentists are required to appropriately treat these medical emergencies. Although in some instances the problem may be relieved by changing the patient’s position or monitoring vital signs, some cases require treatment with emergency drugs. However, there are no standard guidelines in Japan regarding medical emergencies in dentistry and emergency drugs. In contrast, the British Dental Association has created a poster that summarizes the symptoms of medical emergencies, initial treatments, and emergency drugs. The American Dental Association also publishes a response guide to medical emergencies in the dental office. In this paper, referring to these two sources, the authors have reconsidered which emergency drugs are needed for dental clinics in Japan. Daily training in the correct use of drugs in cases of emergency is essential. The authors manage a study group called “AneStem” to respond to sudden changes in the condition of patients at the dental clinic, and we also run educational activities including simulation training for medical emergencies. [ABSTRACT FROM AUTHOR]