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Background: One of the most common outpatient surgeries is cataract surgery which requires a short anesthesia with fast recovery time providing minimal complications. This study aimed to compare sevoflurane with propofol in terms of extubation time and recovery parameters in patients undergoing cataract surgery. Materials and Methods: This randomized controlled clinical trial recruited 60 patients 18-75 years old with ASA 1 and 2 who were candidate for cataract surgery. Patients were randomly divided into two groups (30 patients per group). Group 1 received propofol 100 μg/kg/min and group 2 received sevoflurane 0.5%-1.5% to maintain anesthesia. Demographic data, hemodynamic parameters, surgery data, pain severity and patient satisfaction were recorded. Data were analyzed in SPSS 19 at significance level P<0.05. Results: Patients in both groups matched for demographic characteristics. They showed no significant difference in terms of hemodynamic parameters, duration of surgery and anesthesia, awakening time, extubation time and recovery time. Patients in the two groups did not significantly differ in terms of nausea, vomiting, shivering and pain after the surgery. Patient satisfaction was high in both groups with no significant difference between the two groups. Conclusion: The results showed that propofol and sevoflurane are useful medications for maintaining anesthesia during cataract surgery, and can be used based on patient’s conditions. [ABSTRACT FROM AUTHOR]

Background: Coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass pump may cause systemic inflammatory reactions by releasing cytokines which leads to multiple organ failure. Vitamin C has anti-inflammatory and antioxidant properties. The study aimed to determine the effect of vitamin C on inflammatory markers and atrial fibrillation in patients undergoing CABG. Materials and Methods: In the present single-blind randomized controlled clinical trial, 80 patients were divided to experimental and control groups. The experimental group received vitamin C 2 g IV, and the control group received the same amount (equivalent to 4×5 cc shots) of normal saline IV 10 minutes after induction of anesthesia. Arterial blood samples were taken at specified intervals to assess IL-6 and hsCRP levels. The data were analyzed in SPSS-24. Results: The changes in IL-6 values at the specific intervals were not statistically significant (P> 0.05). Significant differences were observed in hsCRP levels only 24 hours after CABG. The incidence of atrial fibrillation was not significantly different between the two groups after the intervention. Conclusion: This study showed that ascorbic acid has no effect on reducing IL6 and hsCRP levels in patients undergoing CABG, and similarly, does not cause a reduction in post-CABG atrial fibrillation. [ABSTRACT FROM AUTHOR]