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The modern development of animal husbandry and poultry farming is impossible without compound feed, which is balanced in terms of energy indicators, nutrients and biologically active substances. The presence of biologically active substances in the rations of animals leads to an increase in the cost of compound feed, which affects the cost of livestock products. However, an insufficient amount of biologically active substances leads to the occurrence of diseases that exclude the possibility of further effective use of animals. Probiotic feed products based on live cultures of microorganisms are used to ensure the body's need for biologically active substances of farm animals. Probiotic feed supplement EnzActive based on active yeast Saccharomyces cerevisiae is widely used in feeding farm animals. This supplement is able to increase the assimilation of nutrients by blocking the negative impact of harmful microorganisms on the condition of the mucous membranes of the gastrointestinal tract, on the processes of digestion and removal of the end products of metabolism. Based on theoretical and experimental data, a structural scheme for the production of granulated compound feed using EnzActive probiotic feed additive is proposed, which involves stepwise dosing and mixing of microcomponents with EnzActive probiotic feed additive, further mixing with prepared and dosed components of compound feed to ensure high uniformity of EnzActive distribution in the finished product. The technology for the production of granulated combined feed products using the EnzActive probiotic feed additive has been developed, which allows for the production of highly homogeneous finished products with a fixed stable composition that meets the physiological needs of farm animals. The physical properties of loose and granulated compound feed with the EnzActive probiotic feed additive were experimentally determined, which indicate that, compared to loose, granular compound feed with the EnzActive probiotic feed additive, it has a smaller angle of natural slope, better flowability, and greater volume, which leads to space saving during transportation and storage. The main quality indicator of the granulated compound feed is the fragility of the granules, which was 27%. It has been established that the introduction of probiotic feed additive EnzActive into the compound feed does not affect the change in the physical properties of the finished compound feed products. Microbiological indicators were determined, which indicate that the number of yeast cells in the granulated compound feed with the EnzActive probiotic feed additive is 51.6% compared to the number of yeast cells in the loose compound feed with the EnzActive probiotic feed additive.

The paper supplies a theoretical base for the preparation of bioactive substances used to produce highly homogeneous mixtures. It presents theoretical and experimental data on the physical, technological, and chemical properties of vitamin preparations, carbonic and sulphuric acid salts of trace elements. The study has considered the interrelation, compatibility, and manifestations of the effects of synergism and antagonism, the one-sided and mutual influence of major and minor elements, vitamin preparations and minerals. It has been analysed how the composition of the premix, the filler, its properties affect the activity of bioactive substances. Besides, data are presented on how the moisture content, pH, temperature, and physical properties determine the degree of bioavailability of substances. It has been studied how big the particles are and how homogeneously bioactive substances are distributed when mixed with a premix filler. The size and shape of particles have been established to be essential factors when obtaining homogeneous mixtures. The characteristics of bioactive substances have been summarised, and their physical, technological, and chemical properties, the features of their preparation, and the technological stages of manufacturing premixes have been analysed. Based on this, classifications of bioactive substances have been developed for vitamin preparations and salts of trace elements. The step-by-step structure of the compound feed technological system that produces premixes has been described and compared with the earlier technologies. Based on the theoretical and experimental studies, reasons have been given for the classification of bioactive substances into three groups and for their proper preparation during premix production, depending on their bulk density, particle size, and percentage in the composition of premixes: 0.1–2.0 kg/t, 2.0–30.0 kg/t, 30.0–100.0, and more. It has been determined how particles of the premix components range in size (0.04–0.6 mm), and it has been established that the size of the filler particles should not exceed 0.8 mm. The problems of preparing bioactive substances in the premix production have been analysed, and it has been recommended how to solve them in order to obtain homogeneous mixtures, premixes, protein-vitamin supplements, and protein-mineral-vitamin supplements.

The modern development of animal husbandry and poultry farming is impossible without compound feed, which is balanced in terms of energy indicators, nutrients and biologically active substances. The presence of biologically active substances in the rations of animals leads to an increase in the cost of compound feed, which affects the cost of livestock products. However, an insufficient amount of biologically active substances leads to the occurrence of diseases that exclude the possibility of further effective use of animals. Probiotic feed products based on live cultures of microorganisms are used to ensure the body's need for biologically active substances of farm animals. Probiotic feed supplement EnzActive based on active yeast Saccharomyces cerevisiae is widely used in feeding farm animals. This supplement is able to increase the assimilation of nutrients by blocking the negative impact of harmful microorganisms on the condition of the mucous membranes of the gastrointestinal tract, on the processes of digestion and removal of the end products of metabolism. Based on theoretical and experimental data, a structural scheme for the production of granulated compound feed using EnzActive probiotic feed additive is proposed, which involves stepwise dosing and mixing of microcomponents with EnzActive probiotic feed additive, further mixing with prepared and dosed components of compound feed to ensure high uniformity of EnzActive distribution in the finished product. The technology for the production of granulated combined feed products using the EnzActive probiotic feed additive has been developed, which allows for the production of highly homogeneous finished products with a fixed stable composition that meets the physiological needs of farm animals. The physical properties of loose and granulated compound feed with the EnzActive probiotic feed additive were experimentally determined, which indicate that, compared to loose, granular compound feed with the EnzActive probiotic feed additive, it has a smaller angle of natural slope, better flowability, and greater volume, which leads to space saving during transportation and storage. The main quality indicator of the granulated compound feed is the fragility of the granules, which was 27%. It has been established that the introduction of probiotic feed additive EnzActive into the compound feed does not affect the change in the physical properties of the finished compound feed products. Microbiological indicators were determined, which indicate that the number of yeast cells in the granulated compound feed with the EnzActive probiotic feed additive is 51.6% compared to the number of yeast cells in the loose compound feed with the EnzActive probiotic feed additive. [ABSTRACT FROM AUTHOR]

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