11 results on '"Клименко, Я. М.'
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2. Оцінка хронометричних показників швидкості початку терапевтичного ефекту та профілактика рецидивів комплексною фітотерапією пацієнтів з гострим неускладненим циститом.
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Нікітін, О. Д., Грицай, В. С., Клименко, Я. М., Самчук, П. О., Резніков, Г. Д., Ясинецький, М. О., and Красюк, О. Ю.
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ANTIBIOTICS ,URINARY tract infections ,SUPPURATION ,ACUTE diseases ,CYSTITIS ,QUESTIONNAIRES ,DESCRIPTIVE statistics ,URINE ,DYSURIA ,DRUG efficacy ,CO-trimoxazole ,COMBINED modality therapy ,DISEASE relapse ,COMPARATIVE studies ,URINATION disorders - Abstract
Urinary tract infections (UTIs) are a significant public health problem. Every year the situation becomes more complicated due to the high rate of recurrence and the growth of resistance among the population. Research results show that about 150 million people suffer from bacterial infections of the urinary tract every year, and about 6 million visits to the doctor about UTIs are registered in the US every year, of which more than 2 million are related to cystitis. In Ukraine, UTIs rank first among all urological diseases, more than 170,000 cystitis patients are registered annually for the first time. 20% of girls till 20 years old have at least one episode of acute cystitis, and 25–40% of women experience a recurrent episode within a year after an episode of acute cystitis. Treatment of cystitis depends on the influence of many factors, which include: age, gender, state of the immune system, recurrences, urological pathologies, severity of the disease and the risk of developing multiple drug resistance. For the prevention of the antibiotic resistance development, it is recommended to use combined herbal preparations for long-term prevention of episodes of recurrent cystitis. The objective: to evaluate the effectiveness of the use of the proposed herbal preparation in the complex treatment and prevention of recurrence in patients with acute uncomplicated cystitis and the chronometry of the onset of action of the drug in monotherapy. Materials and methods. The study was included the patients with acute uncomplicated cystitis. The main group involved 40 persons who were prescribed antibacterial therapy in the form of a single use of fosfomycin trometamol 3 g per os or sulfamethoxazole/trimethoprim 400 mg/80 mg 2 tablets twice a day for 5 days in combination with a herbal preparation (a combination of medicinal plant components of centaury herb, lovage root and rosemary leaves) 1 tablet 3 times a day for 3 months. Patients of the comparison group (40 subjects) received only antibacterial therapy. Treatment effectiveness and side effects were evaluated 10 days after its initiation. Determination of the presence and frequency of recurrence of the disease was carried out 3 and 6 months after its onset. At the second stage of the study, the effectiveness of the use of the herbal preparation was evaluated as a prevention of recurrence of cystitis and relief of its first signs. At the appearance of the first signs of recurrence of the disease within 6 months after the end of the primary course, patients of both groups were recommended to immediately start using the herbal preparation, 1 tablet three times a day. To determine the speed of the onset of the pharmaceutical action of the drug, each patient was asked to fill out a questionnaire regarding the chronometry of the reduction or disappearance of symptoms. Results. After completion of treatment, a positive effect was observed in 38 (95.0%) patients of the main group and 37 (92.5%) of the comparison group, leukocyturia stopped in 39 (97.5%) and 38 (95.0%) patients, respectively, dysuria – in 37 (92.5%) and 38 (95.0%), respectively. The effect of the proposed herbal preparation was maximally manifested in reducing the rate of recurrence of cystitis, which has important clinical significance. It is quite clear that for the occurrence of a sporadic episode of acute cystitis, timely and effective antibiotic therapy is selfsufficient and accordingly hides the effect of phytotherapy. Use of the proposed herbal preparation for 3 months provides long-term rehabilitation of the lower urinary tract due to the aquaretic and antimicrobial effect of the herbal preparation and prevents the recurrence of the disease. Conclusions. The use of the proposed herbal preparation as part of combined therapy in patients with acute uncomplicated cystitis demonstrated its effectiveness in 95.0% of patients. The appointment of the proposed drug of plant origin prevents the occurrence of recurrence in 97.5% of patients, which allows us to recommend it for use in order to prevent relapses of the disease. The use of the proposed preparation of herbal origin helps to reduce the feeling of incomplete emptying of the bladder, starting from 62.9±17.0 min and the disappearance of pollakiuria – by 179.7±23.0 min, which allows to make quick assess of phytotherapy effectiveness and, if necessary to strengthen it in time. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Відкрита розширена тазова лімфодисекція як валідація результатів проведення мультипараметричної магнітно-резонансної томографії з контрастним підсиленням при виявленні метастатичного ураження лімфовузлів у хворих на рак передміхурової залози проміжного та високого ризику
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Головко, С. В. and Клименко, Я. М.
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PELVIC surgery ,LYMPH nodes ,RISK assessment ,LYMPHADENECTOMY ,PREDICTION models ,PROSTATE-specific antigen ,PROSTATE tumors ,MAGNETIC resonance imaging ,PREOPERATIVE care ,RETROSPECTIVE studies ,TUMOR grading ,DESCRIPTIVE statistics ,METASTASIS ,PROSTATECTOMY ,COMPARATIVE studies ,DATA analysis software ,CONTRAST media ,SENSITIVITY & specificity (Statistics) ,DISEASE risk factors - Abstract
The objective: to evaluate the prognostic significance of the use of multiparametric MRI (mpMRI) with the analysis of such indicators as sensitivity and specificity in patients with prostate cancer (PC) of intermediate and high risk during open extended pelvic lymph node dissection (EPLND) with subsequent histological control. Materials and methods. In a retrospective comparative study, which was conducted during 2011-2021, the medical histories of 517 men who had preoperative mpMRI examination in one highly specialized diagnostic center before the puncture biopsy were analyzed. Intermediate or high-risk prostate cancer was first diagnosed and histologically confirmed in the patients, and open radical prostatectomy (RPE) was performed in two other medical institutions. During the study, MRI parameters such as sensitivity and specificity were analyzed, cases of positive MRI were compared with the results of a pathomorphological examination of lymph nodes (LN) to reveal the relationship between the PSA level, Gleason index, location of the lesion and size of the LN, and the feasibility of radical treatment was also analyzed. Results. During the study, metastases in lymph nodes (LN+) were detected in 31 (5.9%) patients. At the same time, MRI results were positive in 49 (9.4%) patients. Individual sensitivity of mpMRI was 30.4%, specificity - 90.6%. MRI-positive cases were significantly more often detected with an increased number of LN (on average, 5.4 vs. 2.3; p˂0.001) and with larger diameter LN (14.4 vs. 5.3 mm; p<0.05). The results of the study show that the prognostic model using preoperative MRI and risk stratification according to the program of the National Comprehensive Cancer Network of the USA (NCCN) increases the diagnostic accuracy of detecting LN lesions. Conclusions. MRI has a rather limited sensitivity for routine staging of LN. MRI-positive cases are mostly found with significant damage to the LN. In combination with NCCN risk nomograms, preoperative mpMRI may improve the predictive value of studies. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Сечокам'яна хвороба: сучасні підходи до класифікації, діагностики та лікування
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Самчук, П. О., Красюк, О. Ю., Іскендеров, Р. К., Метельський, С. О., Клименко, Я. М., and Грицай, В. С.
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MEDICAL history taking ,PHYSICAL diagnosis ,CONSERVATIVE treatment ,URETEROSCOPY ,URINARY calculi ,COMPUTED tomography ,LAPAROSCOPIC surgery ,LITHOTRIPSY ,MINIMALLY invasive procedures ,EARLY diagnosis ,GENITOURINARY organ radiography ,NEPHROSTOMY ,SYMPTOMS - Abstract
Urinary stone disease (USD) is the most common and progressive disease of the urinary system, which is characterized by frequent exacerbations and a severe course. This is a complex disease caused by various causes, in which several biochemical processes are involved, occurring not only in the urinary system, but also in the whole organism. USD depends on geographical, climatic, ethnic, dietary and genetic factors. Over the past 20 years there has been an increase prevalence of this disease. The course of USD is characterized by the acute and chronic pyelonephritis and frequent recurrence, which leads to the development of renal failure, disability and fatal consequences. Calculus can form de novo anywhere in the urinary tract. The pathophysiology of USD differs depending on the place of stone formation and depends on endogenous and exogenous factors. Urinary tract stones are classified depending on etiology, location, size, number, frequency of occurrence, and radiopacity. The main symptoms of USD are pain of various nature; microscopic hematuria; dysuria, which most often indicates the presence of a stone in the urinary bladder or a low location in the ureters; discharge of crystals of urinary salts or concretions; increased body temperature. The diagnosis of USD is based on a carefully history taking and physical examination, which allows to determine the correct direction of diagnostic approach, which include laboratory and instrumental methods of diagnosis. Ultrasound diagnosis is used as the main method for visualization of calculi, but recently non-contrast-enhanced computed tomography has become the standard for the diagnosis of acute low back pain, replacing intravenous urography. The choice of treatment is based on many parameters, such as the number, size, morphology, shape, volume, mobility, hardness and location of the stones and is individualized for each patient. There are two main approaches: conservative treatment and surgic al one. Medicinal treatment of USD is used primarily to prevent the repeated formation of new stones or to increase those inclusions that are already present in the organs. Drug therapy is carried out with the aim of normalizing processes in the body, the failure of which leads to the development of pathology. However, conservative treatment has its limitations and is most often used as a symptomatic treatment. Open laparoscopic interventions are rarely used recently, minimally invasive methods are more popular: extracorporeal shock-wave lithotripsy; ureterorenoscopy; percutaneous nephrolithotomy. Taking into account the increase in the prevalence of USD in Ukraine and disability (the third place among the general spectrum of causes of disability in urological practice), the article analyzes and reviews modern approaches to classification, early and accurate diagnosis, and choosing a timely and correct method of treatment. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Дослідження ефективності сучасної фітотерапії хворих на доброякісну гіперплазію передміхурової залози та хронічний простатит
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Нікітін, О. Д., Клименко, Я. М., Грицай, В. С., Самчук, П. О., and Красюк, О. Ю.
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COMBINATION drug therapy ,POLLEN ,URINATION ,SAW palmetto ,CLINICAL trials ,PUMPKINS ,PLANT roots ,BENIGN prostatic hyperplasia ,PLANT extracts ,SEEDS ,PROSTATITIS ,DRUG efficacy ,DIETARY supplements ,DRUG tolerance ,THERAPEUTICS ,EVALUATION - Abstract
The objective: to analyze the effectiveness and tolerability of a dietary supplement, which includes: Saw Palmetto (Serenoa repens), pumpkin seeds (Cucurbita moschata), African tuber (Hypoxis hemerocallidea), stinging nettle root (Urtica dioica), African plum bark (Prunus africana), rye pollen extract (Secale cereale), in the treatment of patients with benign prostatic hyperplasia (BPH) and chronic prostatitis (CP) for 6 months. Materials and methods. 60 men were examined, they were divided into two groups: the main group (MG) - 28 patients who received the dietary supplement for 6 months, and the comparison group (CG) - 32 patients who used another combined herbal preparation for the treatment of BPH and CP. MG and CG patients were similar in terms of age, disease duration, and urination rate. Patients of both groups were examined using clinical, laboratory and instrumental methods before the start of treatment and after its completion in 6 months. Results. The main result of the research can be considered that the use of a dietary supplement based on Saw Palmetto (Serenoa repens), pumpkin seeds (Cucurbita moschata), African tuber (Hypoxis hemerocallidea), stinging nettle root (Urtica dioica), African plum bark (Prunus africana), extract of rye pollen (Secale cereale) gives an excellent long-term effect in 96.4% of patients with CP and BPH. As a result of the study, this dietary supplement demonstrated its effectiveness in the treatment of patients with BPH and CP for both subjective (IPSS and QOL, pain sensation) and objective indicators over a period of 6 months. During therapy the volume of residual urine in patients probably decreased and the maximum urinary flow rate increased. Conclusions. Dietary supplement, which includes Saw Palmetto (Serenoa repens), pumpkin seeds (Cucurbita moschata), African tuber (Hypoxis hemerocallidea), nettle root (Urtica dioica), African plum bark (Prunus africana), rye pollen extract (Secale cereale), is well tolerated by patients, has high therapeutic efficiency, does not cause side effects, does not disturb the sexual function of patients with BPH and CP, which allows to prescribe it for a long time. [ABSTRACT FROM AUTHOR]
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- 2023
6. Порівняльна ефективність антибіотикопрофілактики післяопераційних ускладнень трансуретральної резекції простати.
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Самчук, П. О., Резніков, Г. Д., Нашеда, С. В., Клименко, Я. М., and Грицай, В. С.
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DRUG efficacy ,CEFTRIAXONE ,TRANSURETHRAL prostatectomy ,SURGICAL complications ,ANTIBIOTIC prophylaxis ,BENIGN prostatic hyperplasia ,COMPARATIVE studies ,QUALITY of life ,RETENTION of urine ,EVALUATION - Abstract
Benign prostatic hyperplasia (BPH) is one of the most common benign diseases in men, as it leads to an enlarged prostate, the development of lower urinary tract symptoms, and worsens the quality of patient’s life. Surgical treatment is indicated to patients after non-effective drug treatment. Most often, transurethral resection of the prostate (TURP) is used. The objective: to improve the results of TURP in patients with BPH and acute urinary retention by optimizing antibacterial prophylaxis of postoperative complications in the early postoperative period. Materials and methods. An analysis of the surgical treatment of 179 patients with BPH with acute urinary retention after TURP was performed. The age of the patients varied from 51 to 84 years old, the average age was 64.9±5.1 years. All patients had a complex urological examination in the preoperative period. The patients were divided into two groups: I group – 85 patients after operation who were prescribed ceftriaxone in the early postoperative period; II group – 94 patients who received levofloxacin in the early postoperative period. Results. It was determined that complications occurred in 43 (24.1%) patients in the early postoperative period. Long-term macrohematuria was found in 23 (12.9%) patients, exacerbation of chronic pyelonephritis was in 13 (7.3%) patients after operation, acute urethritis developed in 7 (3.9%) patients, acute orchiepididymitis – in 9 (5, 0%) patients. It has been proven that the total frequency of complications in patients with BPH who received levofloxacin in the early postoperative period was statistically significantly lower than in the patients who were prescribed ceftriaxone. Conclusions. The use of levofloxacin for the prevention of early postoperative complications after TURP in patients with BPH complicated by acute urinary retention improves the results of surgical treatment by reducing the frequency of postoperative complications by 60%. [ABSTRACT FROM AUTHOR]
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- 2022
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7. Новий підхід до медикаментозного лікування пацієнтів із симптомами нижніх сечових шляхів, зумовлених доброякісною гіперплазією простати та хронічним простатитом. Чи можлива профілактика раку простати? (Огляд літератури).
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Нікітін, О. Д., Клименко, Я. М., Ясинецький, М. О., Рєзніков, Г. Д., and Сич, В. І.
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PREVENTION of surgical complications ,DISEASE progression ,PROSTATITIS ,CHRONIC diseases ,URINARY tract infections ,BENIGN prostatic hyperplasia ,TRADITIONAL medicine ,DYSURIA ,PLANT extracts ,PROSTATE tumors ,DISEASE complications - Abstract
Today the lower urinary tract symptoms (LUTS) in men are the actual problem. LUTS is an extremely polyetiological problem, but benign prostate hyperplasia (BPH) is the most often reason for its development. The problem of chronic prostatitis (CP) in patient of the older age with BPH is of great importance. These patients have the most pronounced symptoms of the lower urinary tract dysfunction. The therapy of patients with BPH and CP must lead to reducing of LUTS and improvement of quality of life, as well as to complications prevention associated with prostate enlargement and intravesical obstruction, such as acute urinary retention, recurrent urinary tract infection. The modern researches have presented that the combinations of herbal preparation with tamsulosin were more effective than monotherapy with α-adrenoblockers. That is why phytotherapy is considered an alternative option in the treatment of CP as first-line therapy and for the BPH initial stages in the complex treatment with other drugs. In contrast to “traditional” measures with one component, today multicomponent herbal preparations are popular. A natural complex preparation which contains saw palmetto extract (S. Repens), 3.3’-diindolylmethane, pumpkin seed extract, resveratrol, lycopene for hormonal balance normalization for men with BPH was analyzed. The advantage of the natural complex hormonal balance normalization for men with BPH is that it can be prescribed for the first LUTS signs that can prevent the symptoms progression and development of complications. Urologist received the preparation for effective LUTS treatment in patients with BPH and CP, as well for removal of postoperative dysuria. [ABSTRACT FROM AUTHOR]
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- 2022
8. Comparative Analysis of the Sexually Transmitted Pathogens Spectrum in Patients with Benign Hyperplasia and Prostate Cancer
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Пасєчніков, С. П., primary, Клименко, Я. М., additional, and Кравченко, О. В., additional
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- 2019
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9. Comparative Analysis of the Sexually Transmitted Pathogens Spectrum in Patients with Benign Hyperplasia and Prostate Cancer
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Пасєчніков, С. П.; Bogomolets National Medical University, State Institution «Institute of Urology of NAMS of Ukraine», Клименко, Я. М.; Bogomolets National Medical University, Кравченко, О. В.; State Institution «Institute of Urology of NAMS of Ukraine», Пасєчніков, С. П.; Bogomolets National Medical University, State Institution «Institute of Urology of NAMS of Ukraine», Клименко, Я. М.; Bogomolets National Medical University, and Кравченко, О. В.; State Institution «Institute of Urology of NAMS of Ukraine»
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The objective: comparison of infection with sexually transmitted pathogens (STDs), according to the study of genital excrement and intraoperatively removed prostate gland (PZ) in patients with benign prostatic hyperplasia (BPH) and prostate cancer.Materials and methods. 317 patients aged 42 to 83 years (mean age 62 years) were examined. The first group included 122 patients with RP who underwent radical prostatectomy. The second group included 195 patients with BPH, who underwent a planned intermittent prostatectomy in the urological departments of theAlexanderClinicalHospital in Kyiv.Results. The obtained results indicates that STDs DNA in genital excreta and in the removed prostatic tissue in patients with BPH 1.8 times more likely than in patients with the PC. The most common STDs pathogen, detected in the genital excreta and intraoperatively removed prostatic tissue in patients with BPH and PC is Trichomonas vaginalis, which is identified in 26.2% and 14.8% of patients, respectively. In all patients with prostate tumours mollicutes are found more often in the genital excreta than in the intraoperatively removed tissue of the prostate gland (2.4 times more often in patients with BPH and 2 times more often in patients with PC). Trichomonas vaginalis vice versa is found less frequently in genital excreta than in the intraoperatively removed prostate tissue: at BPH 1.1 times rare and at PC 2 times rare. The overall incidence of STD pathogens in removed prostate hyperplasia tissue in patients with BPH is 3.3 times higher than that in prostate cancer patients (p<0.001).Conclusion. The established facts require further study of this problem in order to improve the understanding of the potential role of STD pathogens in the etiopathogenesis of prostate tumors and its impact on the treatment of these tumors., Цель исследования: сопоставление инфицированности возбудителями инфекций, передающихся половым путем (ИППП), по данным исследования генитальных экскретов и интраоперационно удаленной ткани предстательной железы (ПЖ) у больных доброкачественной гиперплазией предстательной железы (ДГПЖ) и раком предстательной железы (РПЖ).Материалы и методы. Обследованы 317 больных в возрасте от 42 до 83 лет (средний возраст – 62 года). В первую группу вошли 122 больных РПЖ, которым была проведена радикальная простатэктомия. Во вторую группу включены 195 больных ДГПЖ, которым была проведена плановая чреспузырная простатэктомия в урологических отделениях Александровской клинической больницы города Киева.Результаты. Полученные результаты позволяют утверждать, что у больных ДГПЖ ДНК возбудителей ЗППП в генитальных экскретах и удаленной ткани ПЖ выявляется достоверно чаще в 1,8 раза, чем у больных РПЖ. Чаще всего возбудителем ИППП, который выявляется при исследовании генитальных экскретов и интраоперационно удаленной ткани ПЖ у больных ДГПЖ и РПЖ является Trichomonas vaginalis, которая идентифицирована у 26,2% и 14,8% пациентов соответственно. У всех пациентов с опухолями ПЖ в генитальных экскретах чаще, чем в интраоперационно удаленной ткани ПЖ, выявлялись моликуты: в 2,4 раза у больных ДГПЖ и в 2 раза пациентов РПЖ. Trichomonas vaginalis, наоборот, в генитальных экскретах выявлялась значительно реже, чем в интраоперационно удаленной ткани ПЖ при ДГПЖ в 1,1 раза и при РПЖ в 2 раза. Общая частота выявления возбудителей ИППП в удаленной гиперплазированной ткани ПЖ больных ДГПЖ в 3,3 раза выше таковой в ткани карциномы ПЖ пациентов с РПЖ (р<0,001).Заключение. Установленные факты требуют дальнейшего углубленного изучения данной проблемы с целью бóльшего понимания потенциальной роли возбудителей инфекций, передающихся половым путем, в этиопатогенезе опухолевых заболеваний предстательной железы и влияния на результаты лечения опухолей указанной локализации., Мета дослідження: співставлення інфікованості збудниками захворювань, що передаються статевим шляхом (ЗПСШ), за даними дослідження генітальних екскретів та інтраопераційно видаленої тканини передміхурової залози (ПЗ) у хворих на доброякісну гіперплазію передміхурової залози (ДГПЗ) та рак передміхурової залози (РПЗ).Матеріали та методи. Обстежено 317 хворих віком від 42 до 83 років (середній вік – 62 роки). До першої групи увійшли 122 хворих на РПЗ, яким була проведена радикальна простатектомія. До другої групи включено 195 хворих на ДГПЗ, яким була проведена планова черезміхурова простатектомія в урологічних відділеннях Олександрівської клінічної лікарні міста Києва.Результати. Отримані результати дозволяють стверджувати, що у хворих на ДГПЗ ДНК збудників ЗПСШ у генітальних екскретах та видаленій тканині ПЗ виявляється вірогідно частіше в 1,8 разу, ніж у хворих на РПЗ. Найчастіше збудником ЗПСШ, що виявляється при дослідженні генітальних екскретів та інтраопераційно видаленої тканини ПЗ у хворих на ДГПЗ і РПЗ є Trichomonas vaginalis, що ідентифікована у 26,2% та 14,8% пацієнтів відповідно. У всіх пацієнтів з пухлин ПЗ у генітальних екскретах частіше, ніж у інтраопераційно видаленій тканині ПЗ, виявляються молікути: у 2,4 разу у хворих на ДГПЗ та в 2 рази – пацієнтів на РПЗ. Trichomonas vaginalis в генітальних екскретах виявляється значно рідше, ніж в інтраопераційно видаленій тканині ПЗ: при ДГПЗ в 1,1 разу та при РПЗ у 2 рази. Загальна частота виявлення збудників ЗПСШ у видаленій гіперплазовній тканині ПЗ хворих на ДГПЗ у 3,3 разу вища за таку в тканині карциноми ПЗ пацієнтів з РПЗ (р<0,001).Заключення. Встановлені факти вимагають подальшого поглибленого вивчення даної проблеми з метою більшого розуміння потенційної ролі збудників ЗПСШ в етіопатогенезі пухлинних захворювань передміхурової залози та впливу на результати лікування пухлин зазначеної локалізації.
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- 2019
10. Features of the composition of hospitalized patients with benign prostatic hyperplasia in the aspect of the outpatient stage of medical care
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Пасєчніков, С. П., primary, Клименко, Я. М., additional, Абдулфатах, Ахмед Моаллім, additional, and Мельничук, Я. М., additional
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- 2018
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11. Features of the composition of hospitalized patients with benign prostatic hyperplasia in the aspect of the outpatient stage of medical care
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Пасєчніков, С. П.; Bogomolets National Medical University, Клименко, Я. М.; Bogomolets National Medical University, Абдулфатах, Ахмед Моаллім; Bogomolets National Medical University, Мельничук, Я. М.; Bogomolets National Medical University, Пасєчніков, С. П.; Bogomolets National Medical University, Клименко, Я. М.; Bogomolets National Medical University, Абдулфатах, Ахмед Моаллім; Bogomolets National Medical University, and Мельничук, Я. М.; Bogomolets National Medical University
- Abstract
The objective: analysis of data on the current composition of patients with benign prostatic hyperplasia (BPH) hospitalized for surgical care.Materials and methods. The study involved 266 patients with BPH, who underwent transurethral resection of the prostate in the profile department of the Aleksandrovsky Clinical Hospital in 2015–2016 in order to assess the general condition of the patients at the time of hospitalization and to identify the problematic issues of providing medical care in ambulatory-polyclinic conditions.Results. It was found out that the significant majority was hospitalized urgently (53,0%), more often in the winter-autumn period of the year (60,4%), the age of which differs be a large percentage of patients under 60 years (12,8% versus 10,4% with a planned one). Among them, men were about 70 years old, 10% were newly diagnosed cases, half of them had symptoms of lower urinary tract (LUT) during 5 years at the time of going to the doctor. With rare exceptions, patients were treated conservatively, took α -adrenoblockers (2/3 to 5 years, 1/3 – 5 to 10 and more years). In 27,8% of patients, there were repeated cases of acute urinary retention (AUR), twice as often among urgently hospitalized ones. Practically all the course of the diseases was complicated by concomitant pathology (1227 nosological units of diseases of different organs and systems). There number increases with age: one patient at 44 to 59 years old had in average 3.0; 60–69 – 4.4; 70–79 – 5.2; ≥80 years – 5.6. Cardiovascular diseases prevail, in every forth there is chronic inflammatory, metabolic syndrome (DM, obesity).Conclusion.The findings confirmed a clear relationship between the volume of the prostate and intravesical prostatic protrusion (IPP) – r=0.33, which was more pronounced with a maximum urination rate (r=0.59) with the residual volume. It was revealed that with the increase of IPP the volume of residual urine decreases with a simultaneous deterioration of the quality, Цель исследования: анализ данных относительно современного состава больных доброкачественной гиперплазией предстательной железы (ДГПЖ), госпитализированных для получения хирургической помощи.Материалы и методы. В исследовании приняли участие 266 больных ДГПЖ, которым в 2015–2016 г. в профильном отделении Александровской клинической больницы г. Киева была выполнена трансуретральная резекция предстательной железы с тем, чтобы оценить общее состояние пациентов на момент госпитализации и выявить проблемные вопросы оказания им медицинской помощи в амбулаторно-поликлинических условиях.Результаты. Установлено, что достоверное большинство пациентов госпитализировано ургентно (53,0%), чаще в зимне-осенний период года (60,4%), возраст большинства из них – до 60 лет (12,8% против 10,4% при плановой). Среди всех превалировали мужчины до 70 лет, 10% приходилось на впервые выявленные случаи заболевания, у половины – на момент обращения к врачу симптомы нижних мочевых путей (СНМП) были 5 лет, у каждого четвертого – 10 и более лет. За редким исключением больные лечились консервативно, принимали α-адреноблокаторы (2/3 до 5 лет, 1/3 – от 5 до 10 и больше лет). У 27,8% пациентов в анамнезе были неоднократные случаи острой задержки мочи (ОЗМ), в два раза чаще среди ургентно госпитализованных. Практически у всех течение заболевания осложнялось сопутствующей патологией (1227 нозологических единиц заболеваний разных органов и систем). Их количество увеличивается с возрастом: на одного больного 44–59 лет в среднем приходилось 3,0; 60–69 – 4,4; 70–79 – 5,2; более 80 лет – 5,6. Преобладают заболевания сердечно-сосудистой системы, у каждого четвертого – хронические воспалительные, метаболический синдром (сахарный диабет, ожирение).Заключение. Подтверждена четкая зависимость между объемом предстательной железы (ОПЖ) и интравезикальной простатической протрузией (ИПП) – r=0,33, которая была более выраженной с максимальной скоростью мочеиспускания (r=0,59) и объемом остаточной мочи. Выявлено, что, Мета дослідження: аналіз даних щодо сучасного складу хворих на доброякісну гіперплазію передміхурової залози (ДГПЗ), госпіталізованих для отримання хірургічної допомоги.Матеріали та методи. У дослідженні взяли участь 266 хворих на ДГПЗ, яким у 2015–2016 р. у профільному відділенні Олександрівської клінічної лікарні м. Києва була виконана трансуретральна резекція передміхурової залози з тим, щоб оцінити загальний стан пацієнтів на момент госпіталізації і виявити проблемні питання надання їм медичної допомоги в амбулаторно-поліклінічних умовах.Результати. Встановлено, що вірогідна більшість пацієнтів госпіталізовані ургентно (53,0%) частіше в зимово-осінній період (60,4%), вік більшості з них – до 60 років (12,8% проти 10,4% при плановій). Серед пацієнтів превалювали чоловіки до 70 років, 10% припадало на вперше виявлені випадки захворювання, у половини – на момент звернення до лікаря симптоми нижніх сечових шляхів (СНСШ) були 5 років, у кожного четвертого – 10 і більше років. За рідкісним винятком, хворі лікувалися консервативно, приймали α-адреноблокатори (2/3 до 5 років, 1/3 – від 5 до 10 і більше років). У 27,8% пацієнтів в анамнезі були неодноразові випадки гострої затримки сечовипускання (ГЗС), у два рази частіше серед ургентно госпіталізованих. Практично у всіх пацієнтів перебіг захворювання ускладнювався супутньою патологією (1227 нозологічних одиниць захворювань різних органів і систем). Їхня кількість збільшується з віком: на одного хворого віком 44–59 років у середньому припадало 3,0; 60–69 – 4,4; 70–79 – 5,2; понад 80 років – 5,6. Переважають захворювання серцево-судинної системи, у кожного четвертого – хронічні запальні, метаболічний синдром (цукровий діабет, ожиріння).Заключення. Підтверджена чітка залежність між об’ємом передміхурової залози (ОПЗ) та інтравезікальною простатичною протрузією (ІПП) – r=0,33, яка була більш вираженою з максимальною швидкістю сечовипускання (r=0,59) і об’ємом залишкової сечі. Виявлено, що зі збільшенням ІПП збільшується обс
- Published
- 2018
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