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OBJECTIVE This cross-sectional study aimed at examining the association between interprofessional collaboration and job satisfaction among the employees of the Greek Organization Against Drugs (OKANA). METHOD The study sample consisted of 97 employees. The research tools used were the Interprofessional Collaboration Scale (ICS) and the Job Satisfaction Survey (JSS). Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS), version 25.0. RESULTS Employees of OKANA assessed the levels of interprofessional collaboration as moderate. A statistically significant relationship with the dimensions of communication and isolation was demonstrated according to specialty, with medical and nursing staff recording higher scores than the other therapeutic staff. Overall job satisfaction ranged in the area of neutrality, with the exception of doctors, who were not satisfied with their work. Regarding specific dimensions of job satisfaction, the nature of work was the factor with the highest scores, and the respondents expressed dissatisfaction concerning the potential for professional development, contingent rewards and fringe benefits. The relationship between interprofessional collaboration and job satisfaction was positive (r=0.36, p<0.001), and linear regression analysis showed that interprofessional collaboration was a positive predictor of job satisfaction (β=0.56, p<0.001). CONCLUSIONS The improvement of interprofessional collaboration through appropriately designed vocational training actions should be a priority for OKANA, aiming at improvement of the sense of satisfaction among the personnel with their job and with the health services provided. [ABSTRACT FROM AUTHOR]