41 results on '"İçen, Mehmet Sait"'
Search Results
2. An Evaluation of Maternal Near-Miss Patient Profiles, the Prevalence, Treatment Approach, Outcomes, and Prognostic Factors: A Retrospective Study.
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AKIN EVSEN, Gamze, EVSEN, Mehmet Sıddık, GÜNDÜZ, Reyhan, İÇEN, Mehmet Sait, and FINDIK, Fatih Mehmet
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DISEASE prevalence ,MATERNAL mortality ,ABRUPTIO placentae ,BLOOD transfusion ,RETROSPECTIVE studies - Abstract
Objective: The aim of this study was to reduce maternal death rates and contribute to the literature by evaluating maternal near-miss (MNM) profiles, the prevalence, treatment approach, outcomes, and prognostic factors. Material and Methods: A total of 217 MNM patients and 19 cases of maternal death were included in this study. The criteria of organ dysfunction, revised by the World Health Organization (WHO) in 2009, was accepted as the criterion for patients defined as MNM. According to WHO's criteria, the patients were classified in 4 groups. These groups were classified as hypertensive pregnancies, hemorrhagic diseases, placental abruption and disseminated intravascular coagulation and other systemic diseases, respectively. Results: The MNM incidence was 2.31 per 100 live births, and the maternal mortality incidence was 202.4 per 100,000 births. The mortality rate of patients transferred to our hospital because of insufficient intervention at another centre was found to be statistically significantly higher. A statistically significant difference was determined in the laboratory parameters between the MNM cases and patients with maternal mortality in Group 1, 2, and Group 3. The rate of blood and blood products transfusion given to MNM patients was statistically significantly higher in Group 3 than in Group 2. Conclusion: The laboratory parameters found to be significant in MNM and maternal mortality cases could have a negative effect on prognosis and could be of guidance in the prediction of mortality. For patients with an insufficient treatment at other centres, transport to suitable centres would reduce maternal mortality by enabling appropriate interventions. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
3. Should women between the ages of 25 and 30 get tested for HPV?
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Gündüz, Reyhan, Ağaçayak, Elif, Bozbay, Özlem Polat, İçen, Mehmet Sait, Gül, Talip, Alabalık, Ulaş, Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı, Gündüz, Reyhan, Ağaçayak, Elif, Bozbay, Özlem Polat, İçen, Mehmet Sait, Gül, Talip, and Alabalık, Ulaş
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Screening program ,Human papillomavirus test ,Cervical cancer ,Papanicolaou smear test ,Young women - Abstract
Objectives: The aim of this study is to discuss whether performing the human papillomavirus test on women aged 25-30 in Turkey has any effect on preventing cervical cancer. It is aimed to reevaluate the screening program. Methods: A total of 400 patients between the ages of 25-30 who had the Papanicolaou smear and the human papillomavirus test were included in our study. Pap smear and the human papillomavirus test were performed again on the patients with a positive human papillomavirus test for high-risk types in accordance with the screening program. Demographical and clinical characteristics of the patients were recorded. The incidence of human papillomavirus test positivity with a high risk among patients aged 25-30, regression, and persistence ratios were calculated. Results: The incidence of human papillomavirus test positivity with a high risk among patients aged 25 to 30 was found to be 7%. Human papillomavirus persistence ratio was 17.6% and the regression ratio was 82.4%. Among patients with a positive high-risk human papillomavirus test between the ages of 25 and 30, human papillomavirus 16 was found in 47.1% of the patients. For one of our patients with a persistent human papillomavirus 16 positivity, conization was performed after the cervical biopsy. Conclusion: We believe that human papillomavirus, which plays an important role in the etiology of cervical cancer, should be screened from the age of 25. This way, we can catch and treat precursor lesions of cervical cancer at earlier ages and lower the incidence and mortality of cervical cancer.
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- 2022
4. Obstetric relaparotomies: 13 years of tertiary care experience.
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FINDIK, Fatih Mehmet and İÇEN, Mehmet Sait
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CESAREAN section ,DELIVERY (Obstetrics) ,TERTIARY care ,POSTPARTUM hemorrhage ,OPERATIVE surgery ,UTERINE rupture - Abstract
Objective: Postpartum hemorrhage is the most common cause of maternal morbidity and mortality. Relaparotomy (RL) is the most serious complication after delivery (normal delivery or cesarean section). RL is very rarely required and mostly performed due to intra-abdominal bleeding. This study aims to show the indications for obstetric RL due to hemorrhage and reveal hemorrhage areas. Material and Methods: A total of 120 patients with an RL history due to cesarean and vaginal postpartum hemorrhage were included in the study. Data such as age, gravida, parity, the procedure performed in an RL, the time between surgeries, complications, and the need for blood transfusion were obtained from clinical files. Descriptive statistical analysis was performed. Results: The RL incidence was 0.44%. Of all RLs, 18.3% (n=22) occurred after vaginal delivery while 81.7% (n=98) occurred after cesarean sections. The indications for an RL were intra-abdominal hemorrhage (83.4%, n=100) and atony (16.6%, n=20). Surgical procedures during an RL were hysterectomy (37.5%, n=45), vascular ligation (19.1%, n=23), secondary suturing (24.1%, n=29), rectus muscle repair (13.3%, n=16), and uterine rupture repair (5.8%, n=7). Conclusion: Close follow-up of the patient after delivery is vital in terms of postpartum hemorrhage. The postpartum RL requirement is 0.44% and it is life-saving. Active management during this period is very significant in terms of reducing maternal morbidity and mortality. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Uterocutaneous fistula: a rare complication after relaparotomy performed due to postpartum haemorrhage
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Gündüz, Reyhan, primary and İçen, Mehmet Sait, additional
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- 2022
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6. Due to Pregnancy İntrahepatic Cholestasis: Evaluation of Fetal & Maternal Outcomes of 48 Pregnancies
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ÖCAL, Aydın, FINDIK, Fatih Mehmet, and İÇEN, Mehmet Sait
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Pregnancy,intrahepatic cholestasis,newborn intensive care ,Gebelik,intrahepatik kolestaz,yenidoğan yoğun bakım ,Medicine ,Tıp - Abstract
Amaç: Kliniğimizde takip edilen gebeliğe bağlı intrahepatik kolestaz tanılı hastaların fetal - maternal sonuçlarının değerlendirilmesi ve bu hastaların gebelik yönetiminin tartışılması.Gereç ve Yöntem: Çalışmamızda Dicle Üniversitesi Kadın Hastalıkları ve Doğum Anabilim Dalı Obstetri kliniğine Ocak 2011 -Aralık 2015 tarihleri arasında başvuran ve gebeliğe bağlı intrahepatik kolestaz (GBİHK) tanısı alan 48 hasta incelendi. Başvuru esnasındaki bilgiler hastane arşivi ve hasta dosyaları incelenerek toplandı.Bulgular: Gebeliğe bağlı intrahepatik kolestaz tanılı hastaların ortalama yaşları 27.6±6.5 idi.. Gebelerin ortalama doğum haftaları 36.1±3.1 idi. Hastaların %48’i (n=23) otuz yedinci gebelik haftasından önce doğum yaptı. 5. dk ortalama APGAR 8.19±1.73 idi. Sezaryen ile doğum oranı %56.25 (n=27) idi. Yeni doğan yoğun bakıma kabul oranı %10.6 idi. Yenidoğan bebeklerin %76.5’i (n=39) erkek %23.5 ‘i (n=12) kız idi. Perinatal mortalite oranı %3.92 idi. Maternal mortalite izlenmedi. Sonuç: Gebeliğe bağlı intrahepatik kolestaz tanısı klinik bulgu ve laboratuvar sonuçlar ile konur. Hastalığın ayırıcı tanısı dikkatli bir şekilde yapılmalı, ayırıcı tanı üzerinde dikkatle durulmalıdır. Antenatal dönemde fetal ve maternal takip dikkatli bir şekilde yapılmalı, tedavi ve doğum süreci hastaya göre planlanmalıdır. Yüksek prematüre doğum riski nedeniyle yenidoğan yoğun bakım ihtiyacı göz önünde bulundurulmalıdır., Objective: To evaluate fetal-maternal outcomes of the pregnancies complicated by intrahepatic cholestasis and to discuss the pregnancy management in our clinic.Material and methods: In this study, Dicle University Obstetrics and Gynecology, Department of Obstetrics clinic in January 2011 -December 2015 between the applicant and pregnancy induced intrahepatic cholestasis (GBİHK) were evaluated in 48 patients diagnosed. Data were collected on admission and patients by providing hospital archive files.Results: The mean age was 27.6 ± 6.5 diagnosis of intrahepatic cholestasis of pregnancy-induced patients. The average gestational age at delivery of the patients was 36.1 ± 3.1. 48% of patients (n=23) gave birth before the thirty seventh week of pregnancy. 5 min Apgar was 8:19 ± 1.73 average. Cesarean birth rate with 56.25% (n=27), respectively. Acceptance rate was 10.6% in the newborn intensive care unit. 76.5% of newborn infants (n=39) were male and 23.5% 'i (n=12) were monitored girl. Perinatal mortality rate was 3.92%. Maternal mortality was observed.Conclusion: İntrahepatic cholestasis of pregnancy depends on the diagnosis made by clinical signs and laboratory results. The differential diagnosis of the disease must be done carefully, the differential diagnosis should be considered carefully. Antenatal maternal and fetal follow-up should be done carefully, treatment and delivery process should be planned according to the patient. Due to the high risk of premature birth neonatal intensive care needs to be taken into consideration.
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- 2020
7. Evaluation of Factors Affecting Perinatal Mortality in Patients with HELLP Syndrome
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GÜNDÜZ, REYHAN, primary, YAMAN TUNÇ, SENEM, additional, İÇEN, MEHMET SAİT, additional, ERTUĞRUL, SABAHATTİN, additional, and GÜL, TALİP, additional
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- 2021
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8. Are serum Netrin-4 levels predictive of preeclampsia?
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İçen, Mehmet Sait, primary, Ağaçayak, Elif, additional, Fındık, Fatih Mehmet, additional, Yaman Tunç, Senem, additional, Kaplan, İbrahim, additional, Tan, İlhan, additional, Evsen, Mehmet Sıddık, additional, and Gül, Talip, additional
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- 2020
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9. The Most Important Factors in Prognosis Of Obstetric Patients with Disseminated Intravascular Coagulation: A Tertiary Center Study
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TURGUT, Abdulkadir, primary, PEKER, Nurullah, additional, AĞAÇAYAK, Elif, additional, AKIN EVSEN, Gamze, additional, AYDIN, Edip, additional, İÇEN, Mehmet Sait, additional, KARAÇOR, Talip, additional, FINDIK, Fatih Mehmet, additional, ÇELİK, Feyzi, additional, DİRİCAN, Emre, additional, and GÜL, Talip, additional
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- 2020
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10. Evaluation Of Patients With Previous C/S + Plasenta Previa Totalis İn 2017
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FİNDİK, Fatih Mehmet, primary, IÇEN, Mehmet Sait, additional, YAMAN TUNÇ, Senem, additional, AĞAÇAYAK, Elif, additional, EVSEN, Mehmet Siddik, additional, and YALİNKAYA, Ahmet, additional
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- 2020
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11. Hypogastric artery ligation in postpartum haemorrhage: a ten-year experience at a tertiary care centre
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İçen, Mehmet Sait, primary, Findik, Fatih Mehmet, additional, Akin Evsen, Gamze, additional, Ağaçayak, Elif, additional, Yaman Tunç, Senem, additional, Evsen, Mehmet Sıddık, additional, and Gül, Talip, additional
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- 2020
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12. Five-Year Retrospective Evaluation of large for gestational age (LGA) infants who Birth Weight of Over 90% Percentile
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Altaş, Hüseyin, primary, İçen, Mehmet Sait, additional, Budak, Hıdır, additional, Bugday, Rezan, additional, Budak, Mehmet Şükrü, additional, and Gül, Talip, additional
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- 2020
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13. Hypogastric artery ligation in postpartum haemorrhage: a ten-year experience at a tertiary care centre.
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İçen, Mehmet Sait, Findik, Fatih Mehmet, Akin Evsen, Gamze, Ağaçayak, Elif, Yaman Tunç, Senem, Evsen, Mehmet Sıddık, and Gül, Talip
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POSTPARTUM hemorrhage , *PLACENTA accreta , *PLACENTA praevia , *TERTIARY care , *CONSERVATIVE treatment , *CESAREAN section , *ARTERIAL surgery , *SPECIALTY hospitals , *TREATMENT effectiveness , *FERTILITY preservation , *LIGATURE (Surgery) - Abstract
This study investigated patients who underwent bilateral hypogastric artery ligation (BHAL) due to postpartum haemorrhage (PPH). Patients who underwent BHAL because of PPH following a conservative treatment were included in this study. Placental abnormalities were referred to as placenta accreta. A total of 130 BHAL procedures took place at the study hospital as a result of PPH. Of these, 39 (30%) were referred to the hospital. The rate of BHAL requirement was 62 out of 10,000 births. Among the 130 patients, the most frequent indication for BHAL was placenta accreta (58.5%). Haematological parameters were poorer among the referral patients. Four of the exitus patients (80%) were referral patients. The mortality rate among the referral patients was 10.25%, whereas this rate was only 1.01% among the patients who gave birth at the hospital. PPH is a life-threatening condition that requires immediate medical attention. BHAL, with its fertility-preserving features, is a good option that can be employed in all PPH patients. BHAL not only preserves patients' fertility, but it also gives them a higher chance of survival.IMPACT STATEMENTWhat is already known on this subject? PPH is a life-threatening condition. Due to the worldwide increase in caesarean sections, placenta accreta has also increased. BHAL is a vital treatment method for PPH.What do the results of this study add? Placenta accreta is one of the most common causes of PPH. Traditional hysterectomy rates can be reduced by replacing this treatment with BHAL in this group of patients. Without early intervention in PPH, a patient's mortality risk can increase by up to 10 times. As research and surgeons' experience grows, PPH can be controlled with treatments with less complex modalities without the need for BHAL.What are the implications of these findings for clinical practice and/or further research? The need for BHAL should be kept in mind when addressing PPH, especially in cases of placenta accreta. The need for hypogastric artery ligation, which is a more aggressive treatment for the surgical correction of the pathology, can be reduced as surgeons' experience increases. Early intervention and/or referral in cases of PPH is of great importance. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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14. Gebeliğe Bağlı İntrahepatik Kolestaz: 48 Vakanın Fetal ve Maternal Sonuçlarının Değerlendirilmesi Due to Pregnancy İntrahepatic Cholestasis: Evaluation of Fetal & Maternal Outcomes of 48 Pregnancies
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ÖCAL, Aydın, primary, FINDIK, Fatih Mehmet, additional, and İÇEN, Mehmet Sait, additional
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- 2018
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15. The Diagnostic Accuracy of Endometrial Sampling in Endometrial Hyperplasia
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Başaranoğlu, Serdar, primary, Ağaçayak, Elif, additional, Hatırnaz, Şafak, additional, Deregözü, Ayşegül, additional, Acet, Mustafa, additional, Yüce, Ebru, additional, Karaçor, Talip, additional, İçen, Mehmet Sait, additional, Evsen, Mehmet Sıddık, additional, and Gül, Talip, additional
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- 2017
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16. A Rare Gestational Trophoblastic Disease: Placental Site Trophoblastic Tumor
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Tunç, Senem Yaman, primary, Ağaçayak, Elif, additional, İçen, Mehmet Sait, additional, Başaranoğlu, Serdar, additional, Evsen, Mehmet Sıddık, additional, Avcı, Yahya, additional, Urakcı, Zuhat, additional, and Gül, Talip, additional
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- 2016
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17. Role of inflammation and oxidative stress in the etiology of primary ovarian insufficiency
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Ağaçayak, Elif, primary, Yaman Görük, Neval, additional, Küsen, Hakan, additional, Yaman Tunç, Senem, additional, Başaranoğlu, Serdar, additional, İçen, Mehmet Sait, additional, Yıldızbakan, Ahmet, additional, Yüksel, Hatice, additional, Kalkanlı, Sevgi, additional, and Gül, Talip, additional
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- 2016
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18. Evaluation of Fetal Congenital Anomalies After 23 Weeks of Gestation: Clinical Analysis of 444 Cases
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Gezginç, Kazım, Karataylı, Rengin, Yazıcı, Fatma, İçen, Mehmet Sait, Acar, Ali, and Selçuk Üniversitesi
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lcsh:R ,lcsh:Medicine ,Congenital anomalies, Antenatal care, Prenatal diagnosis ,lcsh:Gynecology and obstetrics ,Kadın Hastalıkları ve Doğum ,lcsh:RG1-991 - Abstract
AMAÇ: Bu çalışmada amaç, Selçuk Üniversitesi Meram Tıp Fakültesi Obstetri kliniğinde konjenital anomali ile doğan bebeklerde anomali sıklıklarını ve dağılımını tanımlamaktır. GEREÇ VE YÖNTEM: Ocak 2008 ve Aralık 2010 tarihleri arasında 23. Gebelik haftasından sonra tespit edilen fetal konjenital anomaliler retrospektif olarak tarandı. Konjenital anomaliler prenatal olarak veya doğum sonunda tespit edildi. BULGULAR: Ocak 2008 ve Aralık 2010 tarihleri arasında gerçekleşen toplam 7032 canlı ve ölü doğum arasında toplam 444 bebek konjenital anomalili olarak tespit edildi. Ortalama anne yaşı 27,846,48 (15-47 yıl) idi. Doğumdaki ortalama gestasyonel yaş 35.324.5 hafta idi (22-43 hafta). Tüm doğumlar arasında , 106 bebekte (%23,9) santral sinir sitemine ait anomaliler, 77 bebekte (%17,3) multipl konjenital anomaliler, 68 bebekte (%15,3) kardiyovasküler system anomalileri, 66 bebekte (%14,9) sindirim sitemine ait anomalier, 45 hastada (%10,1) ürogenital sisteme ait anomaliler, 33 bebekte (%7,4) hidrops fetalis, 17 bebekte (%3,8) kromozomal anomaliler, 13 bebekte (%2,9) respiratuar sisteme ait anomaliler, 12 bebekte de (%2,7) kas-iskelet sistemine ait anomaliler tespit edildi. SONUÇ: Konjenital anomalili bebeğe sahip ailelerin çoğu sosyokültürel faktörlerden ve dini inanışlarından dolayı gebeliklerini devam ettirdiler. Bu nedenle, çevresel faktörlerin kontrol edilmesi ve prekonsepsiyonel bakım konjenital anomalilerin insidansını azaltmada büyük önem taşımaktadır., OBJECTIVE: In this study it is objected to identify the frequency and distribution of congenital anomalies in babies born at Selçuk University Meram Medical School, Department of Obstetrics and Gynecology. STUDY DESIGN: Fetal congenital anomalies detected after 23 weeks’ of gestation from January 2008 to December 2010 were retrospectively reviewed. Fetal congenital anomalies were diagnosed prenatally or after birth. RESULTS: A total of 444 infants were diagnosed to have congenital anomalies among 7032 live and deceased newborn infants delivered between January 2008-December 2010. The mean maternal age was 27.84±6.48 years (range 15-47 years). The average gestational age at delivery was 35.32±4.5 weeks (range 22-43 weeks). Among all births, 106 infants (23.9%) had nervous system anomalies, 77 (17.3%) had multiple congenital anomalies, 68 (15.3%) had cardiovascular system anomalies, 66 (14.9%) had digestive system anomalies, 45 had (10.1%) urogenital system anomalies, 33 (7.4%) had hydrops fetalis, 17 (3.8%) had chromosomal anomalies, 13 (2.9%) had respiratory system anomalies, 12 (2.7%) had musculoskeletal system anomalies. CONCLUSION: Most of our patients preferred to continue pregnancies with congenital anomalies because of sociocultural and religious beliefs. So, reducing the incidence of congenital anomalies by controlling environmental risk factors and preconceptional care are of great importance.
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- 2011
19. Single intrauterine demise in twin pregnancies: Analysis of 29 cases
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Yaman Tunç, Senem, primary, Ağaçayak, Elif, additional, Yaman Görük, Neval, additional, İçen, Mehmet Sait, additional, Fındık, Fatih Mehmet, additional, Evsen, Mehmet Sıddık, additional, Turgut, Abdulkadir, additional, Başaranoğlu, Serdar, additional, Yıldızbakan, Ahmet, additional, and Gül, Talip, additional
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- 2015
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20. Anencephaly and coexisting malformations: analysis of 35 cases
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Yaman Tunç, Senem, primary, Ağaçayak, Elif, additional, İçen, Mehmet Sait, additional, Fındık, Fatih Mehmet, additional, Yıldızbakan, Ahmet, additional, Yücesoy, Burcu, additional, and Yalınkaya, Ahmet, additional
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- 2015
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21. Should we add unilateral sacrospinous ligament fixation to vaginal hysterectomy in management of stage 3 and stage 4 pelvic organ prolapse?
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Ağaçayak, Elif, primary, Yaman Tunç, Senem, additional, İçen, Mehmet Sait, additional, Başaranoğlu, Serdar, additional, Fındık, Fatih Mehmet, additional, Sak, Sibel, additional, Ceter, Yasemin, additional, Akın, Gamze, additional, and Gül, Talip, additional
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- 2015
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22. Analysis of maternal and perinatal outcomes in cases with twin-to-twin transfusion syndrome (TTTS)
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Başaranoğlu, Serdar, primary, Yaman Tunç, Senem, additional, Turgut, Abdulkadir, additional, Ağaçayak, Elif, additional, Peker, Nurullah, additional, İçen, Mehmet Sait, additional, and Yalınkaya, Ahmet, additional
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- 2014
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23. A rare and catastrophic finding of HELLP syndrome: subcapsular hematoma and/or hepatic rupture
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Turgut, Abdulkadir, primary, Özler, Ali, additional, Başaranoğlu, Serdar, additional, Yaman Tunç, Senem, additional, Ağaçayak, Elif, additional, İçen, Mehmet Sait, additional, and Yalınkaya, Ahmet, additional
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- 2014
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24. Role of inflammation and oxidative stress in the etiology of primary ovarian insufficiency.
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Ağaçayak, Elif, Görük, Neval Yaman, Küsen, Hakan, Tunç, Senem Yaman, Başaranoğlu, Serdar, İçen, Mehmet Sait, Yıldızbakan, Ahmet, Yüksel, Hatice, Kalkanlı, Sevgi, and Gül, Talip
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ACADEMIC medical centers ,INFLAMMATION ,NONPARAMETRIC statistics ,OVARIAN diseases ,STATISTICS ,T-test (Statistics) ,DATA analysis ,OXIDATIVE stress ,DATA analysis software ,DESCRIPTIVE statistics ,MANN Whitney U Test ,DISEASE complications ,THERAPEUTICS - Abstract
Copyright of Turkish Journal of Obstetrics & Gynecology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2016
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25. Single intrauterine demise in twin pregnancies: Analysis of 29 cases.
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Tunç, Senem Yaman, Ağaçayak, Elif, Görük, Neval Yaman, İçen, Mehmet Sait, Fındık, Fatih Mehmet, Evsen, Mehmet Sıddık, Turgut, Abdulkadir, Başaranoğlu, Serdar, Yıldızbakan, Ahmet, and Gül, Talip
- Abstract
Copyright of Turkish Journal of Obstetrics & Gynecology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
26. Anencephaly and coexisting malformations: analysis of 35 cases.
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Tunç, Senem Yaman, Ağaçayak, Elif, İçen, Mehmet Sait, Fındık, Fatih Mehmet, Yıldızbakan, Ahmet, Yücesoy, Burcu, and Yalınkaya, Ahmet
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ANENCEPHALY ,BRAIN abnormalities ,NEURAL tube defects ,HUMAN abnormalities ,PREGNANCY - Abstract
Copyright of Perinatal Journal / Perinatoloji Dergisi is the property of Deomed Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
27. Should we add unilateral sacrospinous ligament fixation to vaginal hysterectomy in management of stage 3 and stage 4 pelvic organ prolapse?
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Ağaçayak, Elif, Tunç, Senem Yaman, İçen, Mehmet Sait, Başaranoğlu, Serdar, Fındık, Fatih Mehmet, Sak, Sibel, Ceter, Yasemin, Akın, Gamze, and Gül, Talip
- Abstract
Copyright of Turkish Journal of Obstetrics & Gynecology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
28. HELLP sendromunun nadir görülen katastrofik bir bulgusu: Subkapsüler hematom ve/veya hepatik rüptür.
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Turgut, Abdulkadir, Özler, Ali, Baflaranoğlu, Serdar, Tunç, Senem Yaman, Ağaçayak, Elif, İçen, Mehmet Sait, and Yalınkaya, Ahmet
- Abstract
Copyright of Perinatal Journal / Perinatoloji Dergisi is the property of Deomed Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
- Full Text
- View/download PDF
29. A comparison of maternal outcomes in complicated vaginal and cesarean deliveries.
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Ağaçayak, Elif, Başaranoğlu, Serdar, Tunç, Senem Yaman, İçen, Mehmet Sait, Fındık, Fatih Mehmet, Sak, Sibel, and Gül, Talip
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CESAREAN section complications ,DELIVERY (Obstetrics) - Abstract
Objective: The purpose of this study was to compare general characteristics, laboratory data and maternal outcomes of patients who experienced complications in the first 24 hours after a normal vaginal delivery or cesarean section. This way, we intended to determine the results of complications in these patients. Methods: Data of patients referred from the peripheral care centers to our tertiary care center in the first 24 hours after a vaginal delivery or cesarean section due to the presence of various complications were screened retrospectively from 2009 to 2013. Clinical and demographic characteristics, results of physical examinations, laboratory parameters (complete blood count, liver and kidney function tests, electrolyte levels and coagulation parameters), indications for cesarean section, mortality rates, maternal morbidities, including blood transfusion requirements, surgical and medical treatments administered in our clinic as well as operations performed in other care centers were noted. Results: A total of 330 patients were included in this study. Of these patients, 285 constituted the postoperative group (C-sections) whereas 45 constituted the postpartum (vaginal deliveries) group. There was no statistically significant difference between the two groups in gravidity, parity, age, vital signs, results of liver and kidney function tests, hemoglobin levels, white blood cell counts and live birth rates. In addition, no significant difference was found between the two groups in maternal morbidity and mortality rates. Although the two groups' hemoglobin and INR values were not significantly different from each other, fresh blood transfusion required in our hospital was significantly higher in the postoperative group compared to the postpartum group (p:0.003). In the postoperative group, hysterectomy was performed in 18 patients (6.3%) and hypogastric artery ligation was performed in 16 patients (5.6%). In the postpartum group, on the other hand, 'hysterectomy + hypogastric artery ligation' was performed in 4 patients (8.8%) and 'hypogastric artery ligation' was performed in one patient (2.2%) (p:0.001). Requirement of relaparotomy was significantly higher in the postoperative group (p:0.007). Conclusion: In the early follow-up, it was found that complicated cesarean sections and vaginal deliveries had similar maternal morbidity and mortality rates, without any advantage of one group to the other. With this in mind, mode of delivery should be selected according to the overall health status of the patient and indications for cesarean section. However, it should also be mentioned that higher requirement of hysterectomy and relaparotomy emerged as an undesirable condition among the postoperative patients in this study. Therefore, larger studies are needed to determine both short term and long term effects of mode of delivery on maternal and neonatal morbidity and mortality rates. [ABSTRACT FROM AUTHOR]
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- 2014
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30. Honokiol decreases intra-abdominal adhesion formation in a rat model.
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Ağaçayak, Elif, Tunç, Senem Yaman, İçen, Mehmet Sait, Alabalık, Ulaş, Fındık, Fatih Mehmet, Yüksel, Hatice, and Gül, Talip
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LIGNANS ,ANTIOXIDANTS ,LABORATORY rats - Abstract
Objective: The purpose of this study was to investigate the effectiveness of honokiol, a natural molecule that was shown to have antioxidant effects, in prevention of intra-abdominal adhesion formation in a rat model. Methods: This study was conducted on a total of 40 non-pregnant Sprague-Dawley rats which were divided into 4 groups as follows: sham, control, saline and honokiol groups. Both uterine horns of the rats in control, saline and honokiol groups were exposed and a 2 cm segment of the antimesenteric surface of both uterine horns was traumatized by a scalpel. The saline group was administered 2 ml of saline/day intraperitoneally for 5 days following the operation. The honokiol group, on the other hand, was administered honokiol intraperitoneally at a dose of 1 mg/kg/day for 5 days following the operation. On postoperative day 14, 3 mL of intracardiac blood sample was taken from the rats for biochemical analyses, and the rats were sacrificed this way. From the blood samples Total antioxidant status (TAC) and Total oxidant status (TOS) levels were studied. The adhesions were evaluated according to the microscopic adhesions classification of Zuhlke et al. Skin tissues were also evaluated for the presence of inflammation, granulation tissue and fibrosis. Results: Adhesion and inflammation scores were all significantly lower in the honokiol group compared to the saline and control groups (p<0.008). Similarly, fibrosis score was significantly lower in the honokiol group compared to the saline group (p<0.008). However, in comparison of TAS and TOS levels; there was no significant difference between groups. Conclusion: Honokiol was found to be effective in prevention of intra-abdominal adhesion formation in a rat model. However, larger studies are needed to shed light on the exact role of honokiol in intra-abdominal adhesion formation and determine the molecular aspects of the promising results found in this study. [ABSTRACT FROM AUTHOR]
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- 2014
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31. Evaluation of Factors Affecting Perinatal Mortality in Patients with HELLP Syndrome
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Talip Gül, Sabahattin Ertuğrul, Reyhan Gündüz, Senem Yaman Tunç, Mehmet Sait Icen, Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı, Gündüz, Reyhan, Tunç, Senem Yaman, İçen, Mehmet Sait, Gül, Talip, and Ertuğrul, Sabahattin
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Perinatal mortality ,medicine.medical_specialty ,Neonatal intensive care unit ,Obstetrics ,HELLP syndrome ,business.industry ,Vaginal delivery ,Birth weight ,Mortality rate ,Gestational age ,medicine.disease ,APGAR score ,Intensive care ,medicine ,Apgar score ,Prematurity ,business - Abstract
OBJECTIVE: To determine the perinatal mortality rate in patients with HELLP syndrome in our clinic and to investigate the factors affecting perinatal mortality. It also makes recommendations to reduce perinatal mortality and contributes to the literature. STUDY DESIGN: Three-hundred-and-eighty-three patients were retrospectively evaluated in this cohort study. The patients' demographic, clinical data, laboratory results, gestational week at delivery, method of delivery, neonatal birth weight, fetal gender, 1- and 5-minute APGAR scores, place of delivery, maternal morbidity, mortality rates, and perinatal mortality rates were recorded. The relationship of these factors with perinatal mortality was investigated. RESULTS: The rate of perinatal mortality was determined as 6%. Patients with HELLP syndrome who experienced perinatal mortality showed significantly lower birth weight, gestational age at delivery, and 1- and 5-minute APGAR score values (p
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- 2021
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32. The evaluation of diagnostic and clinical findings in grand multiparous patients with endometrial cancer.
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Özler, Ali, Turgut, Abdulkadir, Ağaçayak, Elif, İçen, Mehmet Sait, Alabalık, Ulaş, Başaranoğlu, Serdar, Peker, Nurullah, and Gül, Talip
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CANCER risk factors , *PREGNANCY , *ADENOCARCINOMA , *FISHER exact test ,DIAGNOSIS of endometrial cancer - Abstract
Objective: The aim of the present study is to evaluate differences in diagnostic and clinical characteristics of the grand multiparous patients with endometrial cancer comparing with the other patients with endometrial cancer. Methods: A total of 34 patients that operated for endometrial cancer between January 2006 and August 2012 in our clinic were included. The patients were divided into three groups according to the number of births; group 1 (nulliparous patients, n=8), group 2 (the number of delivery from one to four, n=12), group 3 (grand multiparous patients, n=12). The diagnostic, clinical and histopathological data of the patients in the group 3 (grand multiparous patients) were compared with those of the other groups. Results: The mean age of the patients in group 3 (grand multipara) was found to be significantly higher than those of the other groups (p<0.05). There was no significant difference in the depth of myometrial invasion of the tumor between all groups (p>0.05). The percentages of patients with the tumor stage 1A in the groups 1, 2 and 3 were found to be 75%, 64.2% and 83.3%, respectively. All of the grand multiparous patients (group 3) were found to have stage 1 tumor. Conclusion: In conclusion, grand multiparous patients were diagnosed at advanced age but their diseases were endometrioid type endometrial cancer at an early stage. The protective effect of pregnancies against endometrial cancer decreases at advanced age. The period of time after last birth may be a factor on the risk of endometrial cancer. [ABSTRACT FROM AUTHOR]
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- 2013
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33. Comparison of Ultrasound-Guided Drainage with Other Available Treatment Modalities for, Treatment of Tubo-Ovarian Abscess
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M. Hanifi Bademkiran, Nurullah Peker, Talip Gül, Edip Aydin, M. Sait Içen, Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı, İçen, Mehmet Sait, and Gül, Talip
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Surgical treatment ,medicine.medical_specialty ,Medical treatment ,business.industry ,Obstetrics and Gynecology ,medicine.disease ,tubo-ovarian abscess ,USG-guided drainage ,Ultrasound guided ,Treatment modality ,medicine ,Radiology ,Drainage ,Tubo-ovarian abscess ,business - Abstract
Objective: The present study aimed at the retrospective evaluation of the medicalrecords of patients treated for tubo-ovarian abscess (TOA) at our clinic and investigation of the efficacyof USG-guided drainage compared with that of other available treatment modalities. Materialand Methods: Medical records of 100 patients with TOA, who were treated and followed up atthe Department of Gynecology and Obstetrics, School of Medicine, Dicle University between January2009 and April 2015, were reviewed retrospectively. Details such as demographic data, risk factors,clinical and laboratory findings, treatment modalities used, and complications observed wererecorded for each patient. Results: The mean age of the patients was 36.46±11.6 years. Of the 100patients, 10 were menopausal women. Pelvic pain was the most common complaint in all patients(100%). The history of intrauterine or intra-abdominal intervention within six months was themost common risk factor (60.5% patients) for the development of TOA. Of the patients, 25% reportedfever (≥38 °C), 55% had leukocytosis, 85% had high sedimentation rate, and 92% had highCRP levels. The development of leukocytosis was not observed to be associated with the treatmentmodality used (p > 0.05). Of the patients, 38% underwent only medical treatment, 47% underwentmedical treatment followed by surgery, and 15% underwent medical treatment followed by USGguideddrainage. All 34 (72.3%) patients who had undergone surgical treatment required fertilitypreservingsurgery. Intraoperative bowel injury (6.3% patients) and wound site infection (8.5%patients) were among the common complications reported in patients undergoing surgical treatment.The mean duration of hospital stay was 7.9±6 days. The longest mean duration of hospital stay(10.5±3.9 days) was observed in the patients who had undergone USG-guided drainage. Conclusion:Broad-spectrum antibiotic therapy, the first step of treatment in patients with TOA, increasesthe size of abscess. In addition, a significant number of patients with bilateral abscesses require additionalintervention (surgery). Our findings suggest that USG-guided drainage should be consideredonly in patients not responding to medical treatment and not consenting to undergo surgicaltreatment.
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- 2018
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34. Are serum Netrin-4 levels predictive of preeclampsia?
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İlhan Tan, Senem Yaman Tunç, Mehmet Sıddık Evsen, Fatih Mehmet Findik, Elif Ağaçayak, İbrahim Kaplan, Mehmet Sait Icen, Talip Gül, Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı, İçen, Mehmet Sait, Ağaçayak, Elif, Fındık, Fatih Mehmet, Tunç, Senem Yaman, Kaplan, İbrahim, Tan, İlhan, Evsen, Mehmet Sıddık, and Gül, Talip
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Adult ,medicine.medical_specialty ,animal structures ,sFlt-1 ,Positive correlation ,Preeclampsia ,Pre-Eclampsia ,Pregnancy ,Risk Factors ,medicine ,Humans ,In patient ,Fetus ,business.industry ,Obstetrics ,fungi ,Netrin-4 ,Obstetrics and Gynecology ,Hypoxia (medical) ,medicine.disease ,Fetal Blood ,Prognosis ,nervous system ,Case-Control Studies ,Correlation analysis ,embryonic structures ,Female ,Netrins ,medicine.symptom ,business ,Anti-angiogenic effects ,Biomarkers - Abstract
WOS:000610981400003 PMID: 33447992 Objective: To investigate the levels of anti-angiogenic factors, namely sFlt-1 and Netrin-4, in patients with preeclampsia (PE). Material and methods: Cord-blood (UC) sFlt-1 and Netrin-4 concentrations were measured in 30 patients with severe PE, 30 patients with PE and 30 control infants and their mothers (MS). Results: Maternal sFlt-1 levels were significantly higher in the severe PE and PE groups than in the control group. There were no statistical differences among the three groups in maternal and fetal Netrin-4 levels. But Netrin-4 levels were found to be the lowest in the control group and higher in the PE and severe PE groups. The correlation analysis revealed a positive correlation between maternal sFlt-1 levels and maternal Netrin-4 levels (p = 0.012, and r = 0.263), maternal sFlt-1 levels and fetal sFlt-1 levels (p = 0.012, and r = 0.263). Conclusions: There was a positive correlation found between maternal sFlt-1 levels and maternal Netrin-4 levels. We are of the opinion that elevation in levels of Netrin-4 might be secondary to placental hypoxia occurring in PE. The present study led to the consideration of anti-angiogenic biomarkers (sFlt-1 and Netrin-4) on automated platforms for clinical use as an aid in establishing the diagnosis and prognosis of PE.
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- 2019
35. Plasenta previa tanısı olan hastaların hematolojik parametrelerinin plasenta yapışma anomalisi ile ilişkinin değerlendirilmesi
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Kaya, Gülsüm, İçen, Mehmet Sait, and Kadın Hastalıkları ve Doğum Anabilim Dalı
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Blood platelets ,Neutrophils ,Plasenta praevia ,Placenta ,Mean platelet volume ,Obstetrics and Gynecology ,Lymphocytes ,Kadın Hastalıkları ve Doğum - Abstract
Amaç: Bu çalışmanın amacı 2013-2017 yılları arasında hastanemize başvuran plasenta previa tanılı hastaların hematolojik parametrelerinin plasental yapışma anomalileri ile ilişkisinin değerlendirilmesidir. Materyal–Metot: Bu çalışmada Ocak 2013 –Aralık 2017 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi Hastanesi Kadın Hastalıkları ve Doğum Anabilim Dalı Kliniği'ne başvuran, plasenta previa tanısı konulup doğumu kliniğimizde gerçekleştirilen vakalar retrospektif olarak değerlendirilmiştir. Geçirilmiş uterin cerrahisi olmayan plasenta previa tanılı 257 (%33) hasta grup 1'i; geçirilmiş uterin cerrahisi olan 396 (%51) hasta grup 2'yi; kliniğimize sancı veya su gidişi şikayetleri ile başvuran ek hastalığı olmayan 120 (%16) hasta grup 3'ü oluşturmaktadır. Hastalara ait demografik veriler, jinekolojik ve obstetrik öyküleri, doğum anındaki gebelik haftaları, doğum şekli (sezaryen/vajinal doğum), vakanın alınma şekli (acil/elektif), intraoperatif veya postoperatif yapılan kan transfüzyon tipleri ve miktarları, anestezi şekli (genel/spinal), operasyon sırasında veya operasyon sonrası yapılan ek cerrahi işlemler, yenidoğan cinsiyet, ağırlık, 1. ve 5. dakika Apgar skorları, doğum yılı, doğum öncesi hemoglobin, hematokrit, trombosit, lökosit, mpv, nötrofil/lenfosit oranı, trombosit /lenfosit oranları değerlendirildi. Veriler hastanenin elektronik arşiv veri tabanından, hasta dosya bilgilerinden ve ameliyat notlarına ulaşılarak temin edildi. Bulgular: Çalışma hastalarının ortalama yaşları grup 1'de 30.96±6.25; grup 2'de 32.34±5 3; grup 3'de 28.58± 6.7 olarak bulundu. Kliniğimizde plasenta previa insidansının 2013-2017 yılları arasında arttığı tespit edildi. Çalışma gruplarının hemoglobin (HGB) düzeyi, hematokrit düzeyi (HCT), lenfosit sayısı (LYM), eritrosit dağılım genişliği (RDW), platelet dağılım genişliği (PDW) arasında istatistiksel olarak anlamlı fark bulunmadı (p>0.05). Çalışma gruplarının platelet lenfosit oranı (PLR) arasında istatistiksel olarak anlamlı fark bulundu (p< 0.05). Çalışma grupları ortalama platelet volümü (MPV) ve nötrofil lenfosit oranı (NLR) açısından karşılaştırıldığında gruplar arasında istatistiksel olarak anlamlı fark bulunmadı (p>0.05 ). Çalışmadaki Grup 1 hastaların %74'ü (190 hasta) acil , %26'sı (67 hasta) elektif olarak operasyona alınmıştır. Grup 2 hastaların %74'ü (292 hasta) acil , %26'sı ise (104 hasta) elektif olarak operasyona alınmıştır. Grup 1 hastaların %32,7'sine genel anestezi; %67,3'ne de spinal anestezi uygulanırken; Grup 2 hastaların %39,9 oranında genel anestezi , %60,1'ine ise spinal anestezi uygulanmıştır. Çalışmamız oluşturan gebelerin doğurdukları bebeklerin doğum ağırlığı arasında her üç grupta anlamlı fark tespit edilmezken 1. ve 5. dakika apgar değerleri grup 1 ve grup 2'de anlamlı düşük tespit edildi(p0.05). A statistically significant difference was found between the groups' platelet lymphocyte rates (PLR) (< 0.05). Comparing the groups with respect to mean platelet volumes (MPV) and neutrophil lymphocyte rates (NLR), the study found no statistically significant difference (p>0.05 ). In Group 1, 74 % (190) of the patients were operated as emergency case and 26% (67 patients) on selective basis. In Group 2, 74 % (292) of the patients had to be urgently operated, and 26% (104 patients) were operated on selective basis. While in Group 1 32,7% of the patients were operated under general anaesthesia and 67.3% under spinal anaesthesia, the same rates were 39.9% and 60.1% respectively in Group 2. While the study found no statistically significant difference between the birth weights of the newborns in three groups delivered by the prospective mothers comprising the sample of our study, significantly low Apgar scores at 1 and 5 minutes after delivery were found in Group 1 and 2 (p
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- 2019
36. Evre 3-4 pelvik organ prolapsuslarının yönetiminde vajinal histerektomiye unilateral sakrospinöz ligament fixasyonu ekleyelim mi?
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Yasemin Ceter, Senem Yaman Tunç, Sibel Sak, Talip Gül, Elif Ağaçayak, Mehmet Sait Icen, Fatih Mehmet Findik, Gamze Akın, Serdar Başaranoğlu, Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı, Ağaçayak, Elif, Tunç, Senem Yaman, İçen, Mehmet Sait, Ceter, Yasemin, Akın, Gamze, Gül, Talip, and Fındık, Fatih Mehmet
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medicine.medical_specialty ,Blood transfusion ,Sacrospinous ligament fixation ,medicine.medical_treatment ,lcsh:Medicine ,sacrospinous ligament fixation ,Vaginal hysterectomy ,lcsh:Gynecology and obstetrics ,Hospital records ,Fixation (surgical) ,medicine.ligament ,medicine ,In patient ,Clinical Investigation ,lcsh:RG1-991 ,Pelvic organ ,business.industry ,lcsh:R ,Sacrospinous ligament ,Obstetrics and Gynecology ,vaginal hysterectomy ,Vajinal histerektomi ,Surgery ,Pelvic organ prolapse ,Pelvik organ prolapsusu ,Hysterectomy vaginal ,business ,Vaginal Vault Prolapse ,Sakrospinöz ligament fixasyonu - Abstract
PMID: 28913059 Objective: To compare ‘‘vaginal hysterectomy alone’’ with ‘‘vaginal hysterectomy with prophylactic unilateral sacrospinous ligament fixation’’ in terms of intraoperative complications and 1-year anatomic outcomes and symptoms in patients aged over 50 years who presented with stage 3 or 4 pelvic organ prolapse (POP). Materials and Methods: Thirty-five patients underwent vaginal hysterectomy alone and 32 patients underwent vaginal hysterectomy with unilateral sacrospinous ligament fixation because of benign pathology between January 2012, and June 2014, were retrospectively analyzed in this study. The patients’ demographic data and preoperative and intraoperative findings were obtained from the hospital records and noted. The patients were invited by phone to a follow-up visit to assess their 1-year anatomic outcomes and symptoms. Results: There was no significant demographic difference between the patients who underwent vaginal hysterectomy alone and those who had a vaginal hysterectomy with sacrospinous ligament fixation. Both length of operation and hospital stay were significantly longer in the patients who underwent vaginal hysterectomy with sacrospinous ligament fixation (p
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- 2015
37. Konjenital or acquired uterine hysterescopic repairs after pregnancy pathology the results infertile patients
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Kayaalp, Hüseyin, Fındık, Fatih Mehmet, İçen, Mehmet Sait, Kadın Hastalıkları ve Doğum Anabilim Dalı, İçen, M. Sait, Dicle Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, and Kayaalp, Hüseyin
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Uterus ,Obstetrics and Gynecology ,İnfertilite ,Hysteroscopy ,Hysterectomy ,Kadın Hastalıkları ve Doğum ,Histereskopi ,Konjenital uterin anomali ,Congenital uterine abnormality ,Pregnancy ,Infertility ,Pathology ,Abnormalities ,Uterine diseases - Abstract
ÖZET Amaç: Primer, sekonder infertilite tanısı ile başvuran, konjenital veya edinsel uterin pataoloji tespit edilen olgularda histeroskopik onarım sonrası gebelik sonuçlarının incelenmesidir.Gereç ve Yöntem: Bu çalışmada Ocak 2011-Aralık 2014 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniğine primer, sekonder infertilite nedeni ile başvuran hastalara H/S yapıldı. Operasyon esnasında herhangi bir konjenital veya edinsel intrauterin patolojisi olan hastalara müdahale edildi. Müdahale edilen 52 hastaya hastane arşiv kayıtlarından elde edilen telefon numaraları aranarak ulaşıldı. Yapılan klinik çalışmayla ilgili bilgi verilip sözlü onamları alındı. Hastaların operasyon öncesi ve sonrası yaş, gravide, parite, yaşayan çocuk ve diğer demografik yapılarıyla ilgili sorular soruldu. Bu hastaların tamamına önce diagnostik L/S ve H/S yapıldı. Ardından patoloji olduğu izlenen hastalara operatif H/S ile müdahale edildi. Ardından operasyon sonrası gebelik sonuçları değerlendirldi. Bulgular: Primer infertil (Pİ) %46'ı (n=24) idi. Sekonder infertil (Sİ) %54'ü (n=28) idi. Pİ'de gebelik izlenmedi. Sİ'de ise 65 gebelik izlendi. Bu gebeliklerin%69.23'ü (n=45) spontan abortustu,%10,76'ı (n=7) preterm, %20'i (n=13) term doğumdu. Sİ'de hasta başına düşen canlı doğum oranı %53,5'di. Pİ'de operasyon sonrası 17 gebelik tespit edildi. Operasyon sonrası Pİ'de hasta başına canlı doğum oranı %58,3'tü. Bu gebeliklerin %11,7'si (n=2) spontan abortus, %11,7'si (n=2) preterm doğum, %76,4'ü (n=13) term doğumdu. Sİ'de ise operasyon sonrası 31 gebelik tespit edildi. Operasyon sonrası Sİ'de hasta başına canlı doğum oranı %67,8'di. Bu gebeliklerin %32'si (n=10) spontan abortus, %12,9'u (n=4) preterm doğum, %54,8'i (n=17) term doğumdu. Sonuç: Uterin kaviteye konjenital veya edinsel bir patoloji nedeni ile müdahale edilen infertil hastalarda operatif H/S sonrası hastaların spontan abortus sayıları azalırken term doğum ve canlı doğum sayısında artışlar izlendi.Anahtar Kelimeler: İnfertilite, konjenital uterin anomali, histereskopi ABSTRACTAim: The aim of this study was to evaluate the pregnancy outcomes following hysteroscopic repair in women that were admitted with primary or secondary infertility and diagnosed with congenital or acquired uterine abnormalities.Materials and Methods: With this study patients who applied to Dicle University Medical School Gynecology and Obstetrics Department with primary or secondary infertility were underwent hysteroscopy and salpingography (H/S) between January 2011 and December 2014. During the operation patients having a congenital or acquired intrauterin pathology were operated. Patients who had an intervention were contacted on the phone after accessing their phone numbers available in the hospital records. Information about the research was given to patients and informed verbal consent was obtained from each patient. The patients were asked a number of questions regarding preoperative age, gravida, parity, number of children alive, and other demographic characteristics. All the patients underwent diagnostic L/S at first and then H/S. The patients detected with pathology also underwent operative H/S. After the operation pregnancy outcomes were evaluated.Results: Primary infertility (PI) was detected 46%(n=24) and secondary infertility (SI) 54%(n=28) of patients. No pregnancy occurred in patients with primary infertility. Sixty five pregnancies occurred in patients with SI. Of these pregnancies 69.23% (n=45) ended up with spontaneous abortion, 20% (n=13) term delivery, and 10.76% (n=7) preterm delivery. The rate of live birth was 53.5% per patient in SI. After the operation 17 live birth was detected in PI. The rate of live birth was 58.3% per patient in PI after the operation. Of these pregnancies 11.7% (n=2) were ended up with spontaneous abortion, 11.7% (n=2) preterm labor, and 76.4% (n=13) term delivery. After the operation 31 pregnancies were detected in SI. After the operation the rate of live birth was 67.8% per patient in SI. Of these pregnancies 32%(n=10) were spontaneous abortion, 12,9 % (n=4) preterm labor, 54,8% (n=17) term delivery. Conclusion: In patients that were infertile and were operated on due to a congenital and/or acquired abnormality in the uterine cavity, the rate of spontaneous abortion decreased while the rate of term delivery and live birth increased.Key words: Infertility, congenital uterine abnormality, hysteroscopy 57
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- 2017
38. İntrahepatic cholestasis of pregnancy: Evaluation of fetal and maternal outcomes of 48 cases
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Oçal, Aydın, Fındık, Fatih Mehmet, İçen, Mehmet Sait, Kadın Hastalıkları ve Doğum Anabilim Dalı, Dicle Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, and Oçal, Aydın
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İntrahepatik kolestaz ,Cholestasis ,Fetal sonuçlar ,Fetal outcomes ,Gastroenterology ,Intrahepatic cholestasis ,Obstetrics and Gynecology ,Kadın Hastalıkları ve Doğum ,Gastroenteroloji ,Liver ,Risk factors ,Pregnancy ,Gebelik ,Liver diseases - Abstract
Amaç: Perinatoloji kliniğimizde takip edilen gebeliğe bağlı intrahepatik kolestaz tanılı hastaların fetal - maternal sonuçlarının değerlendirilmesi ve bu hastaların gebelik yönetiminin tartışılması.Gereç ve Yöntem: Çalışmamızda Dicle Üniversitesi Kadın Hastalıkları ve Doğum Anabilim Dalı Obstetri kliniğine Ocak 2011 -Aralık 2015 tarihleri arasında başvuran ve gebeliğe bağlı intrahepatik kolestaz (GBİHK) tanısı alan 48 hasta incelendi. Başvuru esnasındaki bilgiler hastane arşivi ve hasta dosyaları incelenerek toplandı.Bulgular: Gebeliğe bağlı intrahepatik kolestaz tanılı hastaların ortalama yaşları 27.6±6.5 idi. Üç hastada çoğul gebelik mevcuttu. Gebelerin ortalama doğum haftaları 36.1±3.1 idi. Hastaların %48'i (n=23) otuz yedinci gebelik haftasından önce doğum yaptı. 5. dk ortalama APGAR 8.19±1.73 idi. Sezaryen ile doğum oranı %56.25 (n=27) idi. Yeni doğan yoğun bakıma kabul oranı %10.6 idi. Yenidoğan bebeklerin %76.5'i (n=39) erkek %23.5 'i (n=12) kız olarak izlendi. Amnion sıvısında mekonyum pasajı oranı % 8.3 (n=4) olarak bulundu. Perinatal mortalite oranı %3.92 idi. Maternal mortalite izlenmedi.Sonuç: Gebeliğe bağlı intrahepatik kolestaz tanısı klinik bulgu ve laboratuvar sonuçlar ile konur. Hastalığın ayırıcı tanısı dikkatli bir şekilde yapılmalı, ayırıcı tanı üzerinde dikkatle durulmalıdır. Antenatal dönemde fetal ve maternal takip dikkatli bir şekilde yapılmalı, tedavi ve doğum süreci hastaya göre planlanmalıdır. Yüksek prematüre doğum riski nedeniyle yenidoğan yoğun bakım ihtiyacı göz önünde bulundurulmalıdır.Anahtar kelimeler: Gebelik, intrahepatik kolestaz, fetal sonuçlar Objective: To evaluate fetal-maternal outcomes of the pregnancies complicated by intrahepatic cholestasis and to discuss the pregnancy management in our clinic.Material and methods: In this study, Dicle University Obstetrics and Gynecology, Department of Obstetrics clinic in January 2011 -December 2015 between the applicant and pregnancy induced intrahepatic cholestasis (GBİHK) were evaluated in 48 patients diagnosed. Data were collected on admission and patients by providing hospital archive files.Results: The mean age was 27.6 ± 6.5 diagnosis of intrahepatic cholestasis of pregnancy-induced patients. Three patients had multiple pregnancies. The average gestational age at delivery of the patients was 36.1 ± 3.1. 48% of patients (n=23) gave birth before the thirty seventh week of pregnancy. 5 min Apgar was 8:19 ± 1.73 average. Cesarean birth rate with 56.25% (n=27), respectively. Acceptance rate was 10.6% in the newborn intensive care unit. 76.5% of newborn infants (n=39) were male and 23.5% 'i (n=12) were monitored girl. The rate of passage of meconium in the amniotic fluid of 8.3% (n=4), respectively. Perinatal mortality rate was 3.92%. Maternal mortality was observed.Conclusion: İntrahepatic cholestasis of pregnancy depends on the diagnosis made by clinical signs and laboratory results. The differential diagnosis of the disease must be done carefully, the differential diagnosis should be considered carefully. Antenatal maternal and fetal follow-up should be done carefully, treatment and delivery process should be planned according to the patient. Due to the high risk of premature birth neonatal intensive care needs to be taken into consideration.Key words: Pregnancy, intrahepatic cholestasis, fetal outcomes 55
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- 2016
39. Üniversitemizde doğum yapan kalp hastalarının 3(üç) yıllık istatiksel incelenmesi
- Author
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Ayçiçek, Sertaç, Gül, Talip, İçen, Mehmet Sait, and Kadın Hastalıkları ve Doğum Anabilim Dalı
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Fetus ,Pregnancy ,Obstetrics and Gynecology ,Morbidity ,Delivery ,Kadın Hastalıkları ve Doğum ,Maternal-child health - Abstract
Çalışmamızın esas amacı tersiyer bir merkez olan hastanemizin kalp hastalığı ve gebelik olgularına ait deneyimini irdelemek, kalp hastalığı olan gebelerin perinatal ve maternal sonuçlarını değerlendirerek, bu tip gebelere en uygun yaklaşımı belirlemeye çalışmak.Ocak 2013 ile aralık 2015 yılları arasında Kadın doğum kliniğimizde yatışı yapılan, sonrasında doğumunu hastanemizin çeşitli birimlerinde (genel ameliyathane, doğumhane ve kalp hastanesi ameliyathanesi) gerçekleştiren, 120 gebe kalp hastası retrospektif olarak incelendi. Gebelerin, kalp hastalığının tipine göre, perinatal ve maternal sonuçları değerlendirildi.Çalışmamızda 120 doğum yapan kalp hastası içinde en sık görülen kardiyak hastalık romatizmal kalp kapak hastalığıydı (%55). Kalp ritim bozuklukları ise ikinci sırada yer aldı (%12,5). IE (Infektif Endokardit) profilaksisi yapılan hasta sayısı 62 olup, oran olarak %51,6 olarak tespit edildi. Çalışmamızda hiçbir hastada maternal mortaliteye rastlanmayıp, 22 hastada post-op kardiyoloji yoğun bakım ihtiyacı olmasından dolayı maternal morbidite olarak sayıldı (%18,3). Yenidoğan mortalite sayısı 2 (%1,66) ve morbidite sayısı ise 6 (%5) olarak tespit edildi. NYHA sınıflamasına göre 20 hasta Sınıf III ve IV, 100 hasta ise Sınıf I ve II kalp hastalarıydı. En sık doğum şekli sezaryen ile doğum olup, çalışmamıza esas teşkil eden 120 hastadan 97' si (%80,8) hasta daha çok obstetrik endikasyonlarla sezaryena alındı.Sonuç olarak kalp hastalığı olan gebeler, bu konuda deneyimli kardiyoloji hekimi, anestezi hekimi ve doğum hekiminin oluşturduğu bir ekip tarafından takip edilmelidir. Doğum sonrası yenidoğan yoğun bakım şartlarına sahip pediatri kliniği ve bu konuda tecrübeli hekimlerin de bulunması gerekir. Uygun yaklaşım ve ekip anlayışı ile olguların büyük bir kısmında ciddi sorunlar olmadan çocuk sahibi olabilirler.Anahtar kelimeler: Kalp hastalığı, Gebelik, Maternal morbidite, NYHA The main purpose of our study is to examine cases of pregnanant patients with heart diseases in our tertiary referral hospital, to evaluate perinatal and maternal outcomes, to determine most appropriate approach to these patients.120 cases of patients with gestational age of 20 weeks or more between 2013- 2015 examined retrospectively. Perinatal and maternal outcomes classified according to type of heart disease.In our study among 120 patients, rheumatic valvular heart disease was the most common (55%), the heart rhythm disorders took second place (12.5%). IE prophylaxis applied patient number was 62, the ratio was found to be 51.6%. Maternal death was not encountered, 22 patients due to need for post-operative cardiology intensive care unit were cited as maternal morbidity beacuse of a variety of reasons(18.3%). Neonatal death number was 2 (1.66%) and the morbidity number was detected as 6 (5%) . 20 patients were class III and IV, 1000 patients were in the range of class I and II according to NYHA classification. The most common form of delivery was caesarean section and 97 (80.8%) of the patients c/s performed had obstetric endication.As a result, pregnant women with heart diseas should be followed by a team of cardiologist, anestshetist, and obstetrician experienced in this regard. Furthermore a pediatrics clinic with a newborn intensive care unit and experienced physician should be present after the birth. With proper approach and team spirit can patients with heart disease have babies without serious problems in most cases.Key words: Heart disease, pregnancy, maternal morbidity, NYHA 100
- Published
- 2016
40. Tuboovaryan apse olgularının 6 (altı) yıllık istatistiksel analizi
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Aydin, Edip, İçen, Mehmet Sait, Dicle Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Aydın, Edip, and Kadın Hastalıkları ve Doğum Anabilim Dalı
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Inflammation ,Surgical treatment ,Fallopian tubes ,USG eşliğinde drenaj ,Ovary ,Obstetrics and Gynecology ,USG guided drainage ,Kadın Hastalıkları ve Doğum ,Abscess ,Retrospective studies ,Treatment ,Tubo-ovarian Abscess (TOA) ,Medikal tedavi ,Drainage ,Pelvic Inflammatory Disease (PID) ,Ovarian diseases ,Tuboovaryan Apse (TOA) ,Cerrahi tedavi ,Pelvik İnflamatuar Hastalık (PIH) ,Ultrasonography ,Medical treatment - Abstract
Amaç: Bu çalışmamızın amacı; kliniğimizde tuboovaryan apse (TOA) tedavisi gören hastaların retrospektif olarak klinik ve laboratuar sonuçlarını değerlendirmek ve uygulanan tedavi yöntemleri ve sonrasında gelişen komplikasyonları incelemektir.Materyal – Metod: Ocak 2009 ve Nisan 2015 tarihleri arasında, Dicle Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğimizde tuboovaryan apse tanısıyla takip edilen 100 hastaya ait kayıtlar retrospektif olarak analiz edildi. Hastalara ait demografik veriler, risk faktörleri, klinik ve laboratuar sonuçları, uygulanan tedavi yöntemleri ve gelişen komplikasyonlar kaydedildi.Bulgular: Hastaların yaşları 15 ile 79 arasında değişmekle beraber, ortalama 36,46 ± 11,6 idi. Hastaların %73'ü multipardı. Hastaların başlıca şikayetleri; pelvik ağrı (%100), ateş (%19) ve vajinal akıntı (%27)'idi. Rahim içi araç kullanım prevelansı %7, pelvik inflamatuar hastalık prevelansı %29 olarak saptandı. Cerrahi girişim öyküsü olan hastaların, son 6 ay içinde geçirilmiş intrauterin veya intraabdominal operasyon prevelansı %60,5 olarak saptandı. Klinik bulgu olarak; hastaların %25'inde 38˚C ve üzerinde ateş, lökosit değerleri için >10.000/μL değer baz alındığında, hastaların % 70'inde lökositoz, >12000/μL baz alındığında hastaların %55'inde lökositoz, hastaların %85'inde yüksek sedimentasyon hızı, %92'sinde C-reaktif protein yüksekliği tespit edilmiştir. Hastaların lökosit değerleri açısından uygulanan tedavi şekilleri arasında istatistiksel olarak anlamlılık tespit edilmedi (p> 0,05). Tüm hastalara medikal tedavi uygulandı. Hastaların 38'inin sadece medikal tedavi ile, 47'sinin medikal tedaviye ek olarak cerrahi tedavi ile, 15'inin medikal tedaviye ek olarak USG eşliğinde drenaj tedavisi ile iyileşme sağladığı tespit edildi. Fertilitesini korumak isteyen hastalara USG eşliğinde, L/S ile veya L/T ile apse drenajı uygulandığı saptandı. Hastaların %10'u postmenopozal dönemde olup, bu hastaların çoğuna rezektif cerrahinin uygulandığı görüldü. Cerrahiye giden tüm hastaların; 17'sine drenaj, 14'üne salpingoooferektomi, 3'üne sadece salpenjektomi, 1'ine histerektomi+salpenjektomi, 2'sine histerektomi+unilateral salpingoooferektomi (TAH+USO), 10'una histerektomi+bilateral salpingoooferektomi (TAH+BSO) uygulandığı saptandı. Cerrahi uygulanan hastalarda gelişen komplikasyonlar incelendiğinde; hastalarımızın % 6,3'ünde intraop bağırsak yaralanması geliştiği ve bu hastalara intraop genel cerrahi tarafından primer bağırsak onarımı yapıldığı tespit edildi. Hastaların % 8,5'inde ise postop dönemde yara yeri enfeksiyonu geliştiği gözlendi. Hastaların hastanede yatış süreleri incelendiğinde; ortalama 7,9 ± 6 gün olarak tespit edildi. Medikal tedavi uygulanan hastaların hastanede ortalama yatış süresi 6,9 ± 2,8 gün, cerrahi tedavi uygulanan hastaların hastanede ortalama yatış süreleri 8,0 ± 8,03 gün ve USG eşliğinde drenaj yapılan hastalarda ise, hastanede ortalama yatış süreleri 10,5 ± 3,9 gün olarak tespit edildi.Sonuç: Morbidite ve mortalite yönünden önemli bir hastalık olan tuboovaryan apsede hastanın yaşı, gebelik istemi ve klinik tablo göz önünde bulundurularak hastaya en uygun tedavi yöntemi seçilmelidir. TOA'yı takip eden yüksek morbidite ve azalmış fertilite oranları nedeniyle hastaların erken tanı alması, medikal tedaviye hemen başlanması ve medikal tedaviye yanıtsız durumlarda cerrahi tedaviye başvurulması oldukça önemlidir. Ayrıca medikal tedaviye cevapsız kalıp tekrardan cerrahi tedavi istemeyen hastalarda USG eşliğinde drenaj da akılda tutulması gereken bir seçenek olmalıdır.Anahtar Kelimeler: Tuboovaryan Apse (TOA), Pelvik İnflamatuar Hastalık (PIH), Medikal Tedavi, Cerrahi Tedavi, USG Eşliğinde Drenaj Aim: The aim of this study was to retrospectively evaluate the clinical and laboratory outcomes of the patients treated at our clinic due to tuboovarian abscess (TOA) and to investigate the procedures used for treatment and posttreatment complications.Materials and Methods: The retrospective analysis included 100 patients who were treated at Dicle University Medical School Department of Gynecology and Obstetrics due to tuboovarian abscess between January 2009 and April 2015. Demographic characteristics, risk factors, clinical and laboratory outcomes, treatment procedures, and posttreatment complications were recorded.Results: The ages of the patients ranged between 15-19 years and the mean age was 36.46 ± 11.6 years. Of all the patients, 73% were multiparous. Most common complaints included pelvic pain (%100), fever (%19), and vaginal discharge (%27). The prevalence of intrauterine device (IUD) use was 7% and the prevalence of pelvic inflammatory disease was %29. The prevalence of history of intrauterine or intraabdominal surgery in patients with a history of surgery was %60,5. Clinical findings of the patients were as follows: %25 of the patients had a temperature of ≥38 °C, leukocytosis was present in %70 of the patients based on a leukocyte count of >10,000 /μL and in %55 based on a leukocyte count of >12,000 /μL, %85 of the patients were present with increased sedimentation rate, and %92 of the patients had high C-reactive protein levels. No statistical significance was observed between the treatment procedures in terms of leukocyte counts (p>0.05). Medical treatment was performed in all the patients, whereas 38 underwent medical treatment only, 47 underwent surgical treatment in addition to medical treatment, and 15 underwent ultrasound USG guided drainage in addition to medical treatment. The patients who wished to preserve fertility underwent USG guided abscess drainage with laparoscopy (L/S) or laparotomy (L/T). Ten percent of the patients were at postmenopausal period and most of these patients underwent respective surgery. Of the patients who underwent surgery, 17 underwent drainage, 14 underwent salpingoooferectomy, 3 underwent salpingectomy only, 1 underwent hysterectomy +salpingectomy, 2 underwent hysterectomy+unilateral salpingoooferectomy (TAH+USO), and 10 underwent hysterectomy+bilateral salpingoooferectomy (TAH+BSO). Among the patients who underwent surgery, %6,3 of them developed intraoperative intestinal injury and primary intestinal repair was intraoperatively performed in these patients by a general surgeon. Postoperative wound site infection occurred in %8,5 of the patients. Overall mean hospital stay was 7.9 ± 6 days, whereas mean hospital stay was 6.9 ± 2.8 days in the patients who underwent medical treatment, 8.0 ± 8.03 days in the patients who underwent surgery, and 10.5 ± 3.9 days in the patients who underwent USG guided drainage.Conclusion: Tubo-ovarian abscess (TOA) remains a serious disease with high rates of morbidity and mortality and thus the ideal treatment modality should be determined based on the age and clinical condition of the patient, and desire for pregnancy. Since TOA leads to high morbidity and decreased fertility rates, a rapid diagnosis of TOA, a prompt initiation of the treatment, and switching to surgical treatment in patients not responding to medical treatment is of prime importance. In addition, USG guided drainage should be kept in mind in the patients not responding to medical treatment and rejecting surgical intervention.Key words: Tubo-ovarian Abscess (TOA), Pelvic Inflammatory Disease (PID), Medical Treatment, Surgical Treatment, USG Guided Drainage 77
- Published
- 2015
41. Single intrauterine demise in twin pregnancies: Analysis of 29 cases.
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Yaman Tunç S, Ağaçayak E, Yaman Görük N, İçen MS, Fındık FM, Evsen MS, Turgut A, Başaranoğlu S, Yıldızbakan A, and Gül T
- Abstract
Objective: To evaluate the maternal and fetal demographic features and clinical aspects of twin pregnancies with single intrauterine demise., Materials and Methods: This retrospective study was conducted in Dicle University Faculty of Medicine, Department of Gynecology and Obstetrics between January 2008 and December 2013. There were a total of 594 twin deliveries in our hospital between the given dates. Twenty-nine of these cases were referred to our hospital by another health center because of a preliminary diagnosis of single intrauterine demise. Maternal age, parity, chorionicity, week of fetal death, gestational week at delivery, mode of delivery, birth weight, Activity, pulse, grimace, appearance, respiration scores, maternal fibrinogen levels at delivery and during pregnancy, stay in the neonatal intensive care unit, and obstetric complications were explored in these 29 cases of single intrauterine demise., Results: The mean age of the 29 patients who were provided antenatal follow-up and delivery services in our hospital was 29.9±6.5 years. Thirteen (44.8%) of the patients were monochorionic, whereas 16 (55.2%) were dichorionic. Intrauterine fetal death occurred in the first trimester in 6 pateints and in the second or third trimester in 23. In addition, 20 (69%) patients underwent cesarean section, whereas 9 (31%) had spontaneous vaginal delivery. Lastly, none of the patients had a maternal coagulation disorder., Conclusion: Twin pregnancies with single intrauterine death can lead to various complications for both the surviving fetus and the mother. Close maternal and fetal monitoring, and proper care and management can minimize complications.
- Published
- 2015
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