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2. Hiportiroidi olgularında antitiroid tedavinin akım-volüm eğrileri üzerindeki etkileri

Author

Arbak, Peri Meram, Bahçebaşı, Zerrin Bicik, Şafak, Alper, Çınar, Yelda, and Ülger, Füsun

Subjects
Solunum Sistemi, Boğaz, Kulak, Burun
Abstract

Astım tanısı bulunmayan 20 hipertiroidi olgusunda anütiroid tedavinin akım-volüm eğrileri üzerindeki etkilerini değerlendirmek üzere prospektif bir çalışma düzenlendi. Antitiroid tedavinin başlangıcında ve üçüncü ayının sonunda hastaların tiroid hormonları (Total T3, Total T4 ve TSH), ultrasonografi ile tiroid bezi volümleri, boyun çevresi ölçümleri ve akım-volüm eğrileri değerlendirildi. Propilüourasil tedavisi ile tiroid bezi volümünde ve boyun çevresi ölçümünde istatistiksel olarak anlamlı azalma görüldü (sırasıyla; p 0.001 ve p 0.001). Çalışmanın en önemli sonucu maksimal ekspirasyon ortası akım hızı (MMEFR) parametresinde üç aylık propiltiourasil tedavisi sonrası görülen düzelme idi. Vital kapasitenin %25'indeki ortalama ekspiratuar akım hızı (FEF_{25}) ve vital kapasitenin %75'indeki ortalama ekspiratuar akım hızı (FEF_{75}) parametrelerinde kaydedilen artışlar tüm ekspiratuar akım parametrelerindeki düzelme ile uyumluydu (sırasıyla; p 0.044 ve p 0.012). Sonuçta hipertiroidi tedavisi için propiltiourasil kullanan hastaların akım-volüm eğrilerinde en erken değişiklik ekspiratuar akım parametrelerindeki düzelme olarak bulundu. This prospective study was designed to evaluate the effects of hyperthyroidism on flow-volume loops in nonasthmatic 20 patients with hyperthyroidism. Thyroid related hormones (Total T3, Total T4 and TSH), thyroid gland volumes with ultrasonography, circumference of neck values and flow-volume loops were obtained at the beginning and after three months of antithyroid treatment. Propylthiouracil treatment was followed by a statistically significant decrease in thyroid gland volume and circumference of neck (p< 0.001 and p< 0.001, respectively). The most significant result was improvement of maximum midexptratory flow rate (MMEFR) after propylthiouracil therapy for three months (p 0.003). Increases in mean forced expiratory flow after 25% of FVC has been exhaled (FEF_{25}), mean forced expiratory flow after 75% of FVC has been exhaled (FEF_{75})values were found consistent with the puerall improuement in expiratory flow parameters (p 0.044, p 0.072 respectively) in conclusion, we speculated that improvement of expiratory flow parameters might be the earlier changes in flow volume loops of patients who were treated with propylthiouracil for hyperthyroidism.

Published
2004

4. Akciğer Tutulumu Olan Sistemik Amiloidoz Olgu Sunumu.

Author

Şen, Elif, Kaya, Akın, Kılıçkap, Mustafa, Ülger, Füsun, Erekul, Selim, Kervancıo&#x011Fllu, Celal, and Demirel, Yavuz

Subjects
AMYLOIDOSIS, LUNG diseases, LUNG biopsy, BRONCHOSCOPY, LYMPHOPROLIFERATIVE disorders, PROTEIN metabolism disorders
Abstract

Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2008

6. Long term effects of tear gases on respiratory system: analysis of 93 cases.

Author

Arbak P, Başer I, Kumbasar ÖO, Ülger F, Kılıçaslan Z, and Evyapan F

Subjects
Case-Control Studies, Humans, Male, Odds Ratio, Respiratory Function Tests, Time Factors, Public Health Surveillance, Respiratory System drug effects, Tear Gases adverse effects
Abstract

Aim: This study aimed to assess the long-term respiratory effects of tear gases among the subjects with history of frequent exposure., Materials and Methods: A questionnaire by NIOSH and pulmonary function tests was performed in 93 males exposed to the tear gases frequently and 55 nonexposed subjects., Results: The mean numbers of total exposure and last 2 years exposure were 8.4 ± 6.4 times, 5.6 ± 5.8 times, respectively. Tear gas exposed subjects were presented with a higher rate for cough and phlegm more than 3 months (24.7% versus 11.3%, P > 0.05). Mean FEV1/FVC and % predicted MMFR in smoker exposed subjects are significantly lower than those in smoker controls (81.7% versus 84.1%, P = 0.046 and 89.9% versus 109.6%, P = 0.0004, resp.). % predicted MMFR in nonsmoker exposed subjects is significantly lower than that in nonsmoker controls (99.4% versus 113.1%, P = 0.05). Odds ratios for chest tightness, exercise dyspnea, dyspnea on level ground, winter morning cough, phlegm, and daily phlegm were increased almost 2 to 2.5 folds among tear gas exposed subjects., Conclusion: The rates for respiratory complaints were high in the case of the exposure to the tear gases previously. Tears gas exposed subjects were found to be under the risk for chronic bronchitis.

Published
2014
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