13 results on '"Özge Turgay Yildirim"'
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2. Cardiovascular System Features of Young Adults Born By Cesarean Section
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Ercan AKŞIT, Emine GAZI, Bahadır KIRILMAZ, Melike EDINCIKLIOĞLU, Hasan BOZKURT, Özge Turgay YILDIRIM, and Fatih AYDIN
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epicardial fat tissue ,intima media thickness ,heart rate variability ,cesarean section ,Medicine - Abstract
Aim:Currently, the prevalence of caesarean section (CS) has been increasing at an alarming rate across the world. In parallel with the increasing rate of CS, it is reported that there is an increasing prevalence of obesity, autoimmune and allergic diseases. The purpose of the present study is to analyse whether the cardiovascular system characteristics of young adults born by CS are different from those of young adults born by vaginal delivery (VD).Materials and Methods:A total of 112 participants were included in the study (40 CS group vs 82 VD ie control group). Transthoracic echocardiography and carotid Doppler ultrasonography were performed to the participants. In addition, participants were evaluated with a 24-hour ECG recording.Results:Tricuspid E wave, tricuspid A wave and tricuspid E/A ratio were lower in the CS group compared with the control group (57.6±8.6 vs. 72.4±10.3, p
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- 2020
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3. Evaluation of acute anterior myocardial infarction cases with de-Winter T waves by coronary angiography images
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Mustafa Emin Canakci, Özge Turgay Yildirim, Nurdan Acar, and Kadir Ugur Mert
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Introduction: Acute myocardial infarction (AMI) is the leading cause of mortality worldwide and with immediate invasive strategy, the extent of myocardial injury can be reduced. In recent studies, de-Winter T waves were defined as a sign of proximal left anterior descending artery (LAD) occlusion. In this electrocardiography (ECG) pattern, no ST elevation is seen, but an upsloping ST segment depression (>1mm) beginning from J-point, and symmetrical, long and significant T waves are seen in precordial leads. Case reports: We present three patients who were admitted to emergency department with symptoms of chest pain. Their ECGs revealed de-Winter T waves, therefore, coronary angiography was performed. Total LAD occlusion was observed in all patients, and stents were implanted to the culprit lesion. Conclusion: We aim to emphasize the importance of de-Winter T waves since physicians should recognize this ECG pattern immediately in emergency situations to provide appropriate treatment to STEMI patients.
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- 2019
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4. COVID-19 enfeksiyonunda yoğun bakımda BNP'nin prognostik bir biyobelirteç olarak yeniden tanımlanması
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Özge TURGAY YILDIRIM, Ayşe AYYILDIZ, and Selim YILDIRIM
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General Medicine - Abstract
Aim Coronavirus disease 2019 (COVID-19) has caused a global pandemic and increased mortality has forced researchers to identify prognostic factors to identify patients at higher risk of mortality. In this study, we aimed to investigate the usability of Brain natriuretic peptide (BNP) as a predictor of mortality in critically ill patients hospitalized in the intensive care unit. Material and Method This retrospective study included 50 patients diagnosed with COVID-19 and followed in the intensive care unit. Patients with known heart failure who were found to have heart failure on echocardiography during follow-up were excluded from the study. Results The patients were divided into two groups based on their mortality status during hospitalization in the intensive care unit. These groups were found to be statistically similar in terms of chronic disease, gender and age (p>0.05). Non-survivor group had higher levels of BNP at the admission to intensive care unit when compared to survivor group (93.2 pg/mL (43.5-357.3) vs. 62.9 (25.0-147.1), p=0.004, respectively). Regression analysis revealed that higher BNP levels and lower lymphocyte counts can be used as a predictor of mortality for these patients. ROC curve analysis indicated that best cut-off value for predicting in-hospital death for BNP was 85.6 pg/mL with a sensitivity of 73.1% and a specificity of 70.8%. Conclusions High BNP levels at admission to the intensive care unit can be used as an in-hospital mortality indicator in COVID-19 patients followed up in the intensive care unit.
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- 2022
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5. Prolongation of QTc interval due to increased parity and great grand multiparity
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Mehmet Özgeyik and ÖZGE TURGAY YILDIRIM
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Adult ,Electrocardiography ,Parity ,Diastole ,Pregnancy ,Risk Factors ,Humans ,Obstetrics and Gynecology ,Female ,Prospective Studies - Abstract
Women are more prone to cardiac arrhythmias. Increased exposure to sex hormones may alter the ventricular repolarisation of the heart as the parity number increases. In this study, we aim to investigate the effect of parity number to electrocardiographic parameters. A total of 205 adult women were included for the study. Nulliparous (NP), primiparous (PP), multiparous (MP), grand multiparous (GMP) and great grand multiparous (GGMP) women constituted the study population. Increased parity has positive correlation with QTc interval (
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- 2022
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6. Comment on: 'Basic Life Support: an accessible tool in layperson training'
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Özge Turgay Yildirim and Ayşegül Turgay
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Medicine (General) ,Layperson ,Medical education ,Emergency Medical Services ,R5-920 ,MEDLINE ,Basic life support ,General Medicine ,Psychology ,Training (civil) - Published
- 2020
7. Investigation of mortality rates and the factors affecting survival in out-of-hospital cardiac arrest patients
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Ayşe Ayyıldız, Fatih Alper Ayyıldız, Özge Turgay Yıldırım, and Göknur Yıldız
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Aged ,cardiopulmonary resuscitation ,mortality ,Medicine (General) ,R5-920 ,Physiology ,QP1-981 - Abstract
AbstractBackground It is known that even if spontaneous circulation returns after cardiopulmonary resuscitation(CPR) in geriatric out-of-hospital cardiac arrests(OHCA), the overall one-year survival rate of these patients is very low. In our study, we aimed to investigate the factors affecting survival in OHCA cases.Methods OHCA patients over 18 years of age were examined in two different groups as 18–64 years old and over 65 years old. Demographic data, comorbidities, cardiac arrest rhythms and minutes, and the number of days they were hospitalized in the intensive care unit were recorded.Results The mean age was 65.9 ± 15.8 years and 39.9% (n = 110) of the patients were female. The number of intensive care unit stays was significantly higher in the over-65 age group (p = 0.011). The mortality rate and one-year survival rate were significantly lower in the over-65 age group (p
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- 2023
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8. Assessment of secondary prevention awareness among patients with coronary artery disease: A survey including patients from 3 centers
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Fatih Aydın, Ercan Akşit, Özge Turgay Yıldırım, Ayşe Hüseyinoğlu Aydın, and Murat Samsa
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Medicine ,Internal medicine ,RC31-1245 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2021
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9. A dilemma for women: having many children risks deterioration of diastolic functions
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Mehmet Ozgeyik, Ozge Turgay Yildirim, Mevlut Serdar Kuyumcu, and Mehmet Ali Astarcioglu
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pregnancy ,echocardiography ,left ventricular dysfunction ,Gynecology and obstetrics ,RG1-991 - Abstract
Background: Echocardiography is the most widely used diagnostic tool for detecting changes in cardiac function. Pregnancy is a dynamic process that affects the cardiovascular system and recent studies have shown that increased parity may cause irreversible changes in the cardiovascular system. In this study, we aimed to evaluate echocardiographic changes in women, especially grand multiparous (6 to 9 parities) and great grand multiparous (more than 9 parities) women, after all their pregnancies had finished. Methods: This was a cross-sectional study and contained 195 female patients. Women with one delivery were defined as primiparous (PP), 2 to 5 deliveries were defined as multiparous (MP), 6 to 9 deliveries were defined as grand multiparous (GMP) and more than 9 deliveries were defined as great grand multiparous (GGMP). Results: The mean age at cardiac evaluation was 50.6 ± 16.3 and mean parity was 6.5 ± 4.2. Diastolic dysfunction was grouped as grade 1–3 and this was determined according to the E/e’ ratio. Spearman correlation analysis showed that diastolic dysfunction had positive correlations with parity, age, hypertension, and diabetes mellitus. Receiver-operating curve (ROC) analysis showed that the best cut-off value of the parity number for predicting left ventricular diastolic dysfunction was 6.5, with 66.3% sensitivity and 66.7% specificity. Discussion: In the present study, we showed that diastolic dysfunction significantly increased as the number of pregnancies increased. Additionally, the cut-off value of parity for diastolic dysfunction was 6.5 which is higher than other studies.
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- 2021
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10. Short term follow-up of a patient with uncomplicated type B aortic dissection under dabigatran treatment
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Özge Turgay Yıldırım, Mustafa Emin Çanakçı, Fatih Aydın, Ayşe Hüseyinoğlu Aydın, and Ercan Akşit
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atrial fibrillation ,computerized tomography ,dabigatran ,type b aortic dissection. ,Medicine ,Internal medicine ,RC31-1245 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
This case report illustrates the follow-up of a 57-year-old female with a type B aortic dissection (AD) under dabigatran treatment. The patient had been operated on 8 years earlier due to type A AD. The aortic valve was repaired and a 26-mm polyester fiber graft was applied to the ascending aorta and the aortic arch. In computerized tomography scans taken after the procedure, a dissection flap extending from the descending aorta to the iliac arteries was seen, but the patient was asymptomatic and no further surgery was performed. The patient was subsequently diagnosed with atrial fibrillation. A CHA₂DS₂VASc score of 3 was recorded and dabigatran treatment was initiated. The aortic aneurysm and dissection were followed up via computed tomography and echocardiography at regular intervals, and at 6 months no progression was seen. No thromboembolic or hemorrhagic events were observed. To our knowledge, this is the first case report of dabigatran treatment for a patient with a type B AD. Based on this case, the use of dabigatran would appear to be safe in a patient with an uncomplicated type B AD, but the results of this case need to be confirmed with extended follow-up and additional patients.
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- 2019
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11. Chest pain score: a novel and practical approach to angina pectoris. A diagnostic accuracy study
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Fatih Aydin, Ercan Aksit, Ozge Turgay Yildirim, Ayse Huseyinoglu Aydin, Evrin Dagtekin, and Murat Samsa
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Chest pain ,Angina pectoris ,Myocardial ischemia ,Medicine - Abstract
ABSTRACT BACKGROUND: The chest pain classifications that are currently in use are based on studies that are several decades old. Various studies have indicated that these classifications are not sufficient for determining the origin of chest pain without additional diagnostic tests or tools. We describe a new chest pain scoring system that examines the relationship between chest pain and ischemic heart disease (IHD). DESIGN AND SETTING: Cross-sectional study conducted in a tertiary-level university hospital and two public hospitals. METHODS: Chest pain scores were assigned to 484 patients. These patients then underwent a treadmill stress test, followed by myocardial perfusion scintigraphy if necessary. Coronary angiography was then carried out on the patients whose tests had been interpreted as positive for ischemia. Afterwards, the relationship between myocardial ischemia and the test score results was investigated. RESULTS: The median chest pain score was 2 (range: 0-7) among the patients without IHD and 6 (1-8) among those with IHD. The median score of patients with IHD was significantly higher than that of patients without IHD (P = 0.001). Receiver operating characteristic analysis showed that the score had sensitivity of 97% and specificity of 87.5% for detecting IHD. CONCLUSION: We developed a pre-test chest pain score that uses a digital scoring system to assess whether or not the pain was caused by IHD. This scoring system can be applied easily and swiftly by healthcare professionals and can prevent the confusion that is caused by other classification and scoring systems.
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- 2019
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12. Glu 298-Asp And T786-C Polymorphisms Of Endothelial Nitric Oxide Synthase Gene In Coronary Artery Disease Patients
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Yücel Kaçmaz, Hanefi Yekta Gürlertop, Özge Turgay Yıldırım, Ercan Akşi̇t, and Fatih Aydın
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endothelial nitric oxide synthase ,coronary artery disease ,nitric oxide ,t-786c polymorphism ,glu298-asp polymorphism ,endotelyal nitrik oksit sentaz ,koroner arter hastalığı ,nitrik oksit ,t-786c polimorfizmi ,glu298-asp polimorfizmi ,Medicine - Abstract
Aim: We aimed to investigate the association of eNOS gene with Glu298-Asp and T-786C polymorphisms with Coronary artery disease (CAD) and to contribute to the elucidation of the genetic factors involved in the development of CAD. Patients and Methods: A total of 200 patients were evaluated. Severe CAD was defined as ≥ 50% stenosis in at least one of major coronary arteries and these patients were taken into the CAD group (n=144). Patients without stenosis were included in the control group (n=66). Results: After the evaluation of T-786C polymorphism, there was no significant dif-ference between TT (p=0,660), TC (p=0,73) and CC (p=0,634) genotypes between CAD and control groups. There was no significant difference between the groups in both dominant (p=0,439) and recessive (p=0,622) model comparisons. When Glu 298-Asp polymorphism was examined, there was no statistically significant difference between GG (p=0,836), GT (p=0,581) and TT (p=0,767) genotypes when the groups were compared according to genotype distributions. The groups were statistically similar according to both dominant (p=0,697) and recessive (p=0,485) model com-parisons. Conclusion: There was no statistical correlation between T-786 C and Glu 298-Asp polymorphisms and CAD. Similar studies with larger study populations should be conducted to clarify the role of T-786 C and Glu 298-Asp polymorphisms.
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- 2019
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13. Ankilozan spondilit hastalarının diürnal kan basıncı değişkenliğinin normal popülasyonla karşılaştırılması
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Ercan Akşit, Ayşe Hüseyinoğlu Aydın, Evrin Dağtekin, Fatih Aydın, Emel Gönüllü, and Özge Turgay Yıldırım
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ankilozan spondilit ,diürnal kan basıncı değişkenliği ,hipertansiyon ,ambulatuar kan basıncı monitorizasyonu ,ankylosing spondylitis ,diurnal blood pressure variability ,hypertension ,ambulatory blood pressure monitorization ,Medicine (General) ,R5-920 - Abstract
Amaç: Ankilozan spondilit AS hastalarında kardiyak tutulum %10-30 oranında görülür. Kronik inflamasyon, ankilozan spondilitte olduğu gibi kardiyovasküler hastalıklar, hipertansiyon ve diürnal kan basıncı değişkenliğinin patofizyolojinde rol almaktadır. Azalmış kan basıncı değişkenliği kardiyovasküler olaylar için yüksek risk göstergesidir. Bu çalışma ile amacımız AS hastalarında diürnal kan basıncı değişikliğinin normal popülasyonla karşılaştırılmasıdır. Gereç ve Yöntem: Bu çalışma için 25 AS hastası ve 32 kontrol alınmıştır. Hipertansif hastalar, hipertansif tedavi almakta olan veya ambulatuar kan basıncı monitorizasyonu ABPM sonuçlarına göre gündüz kan basıncı ortalaması SKB/DKB>135/85 mmHg ve/veya gece kan basıncı ortalaması SKB/DKB>120/70 mmHg olması şeklinde tanımlanmıştır. Dipper paterni gece kan basıncı ortalamasının gündüze oranla %10 ve daha fazla düşmesi olarak tanımlandı. Bulgular: Araştırmanın yaş ortalaması 42.5±12.1 yıldır ve % 63.2'si erkektir. Kontrol grubu ve AS grupları arasında temel demografik özellikler açısından anlamlı fark yoktur. ABPM sonuçlarına göre; AS grubunun %36’sı n=9 ve kontrol grubunun %46.9’u n=15 hipertansif olarak belirlenmiştir ve gruplar arasında istatistiksel fark saptanmamıştır p=0.290 . AS hastaları ve kontrol grubu arasında ortalama, gündüz ve gece; sistolik ve diyastolik kan basıncı sonuçları açısından anlamlı fark saptanmamıştır p>0.05 . AS hastalarının %76.0’ında n=19 ve kontrol grubunun %71.8’inde n=23 non-dipper patern saptanmıştır. Bu oranlar arasındaki fark istatistiksel açıdan anlamlı değildir p=0.949 . Gece gündüz arası sistolik kan basıncı değişkenlikleri açısından gruplar arasında fark saptanmamıştır p=0.772 .Sonuç: Çalışmamızın sonuçlarına göre non-dipper paterni ve diürnal kan basıncı değişimi AS hastalarında ve kontrol grubunda benzerdir. Hipertansif ve normotansif hastalar alt grup analizinde değerlendirildiğinde de gruplar arasında non-dipper hastaları ve diürnal kan basıncı değişkenliği açısından fark saptanmamıştır
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- 2019
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