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9. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): fourth Paediatric EUROMACS (Paedi-EUROMACS) report

Author

CTC, Circulatory Health, Rohde, Sofie, van Puyvelde, Joeri, Veen, Kevin M., Schweiger, Martin, Biermann, Daniel, Amodeo, Antonio, Martens, Thomas, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike S., Loforte, Antonio, Pace Napoleone, Carlo, Nemec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuriy, Ramjankhan, Faiz, Sandica, Eugen, Sliwka, Joanna, Stiller, Brigitte, Kadner, Alexander, Franceschini, Alessio, Thiruchelvam, Timothy, Zimpfer, Daniel, Berger, Felix, Davies, Ben, Dashkevich, Alexey, Stark, Christoffer, Meyns, Bart, de By, Theo M.M.H., Miera, Oliver, CTC, Circulatory Health, Rohde, Sofie, van Puyvelde, Joeri, Veen, Kevin M., Schweiger, Martin, Biermann, Daniel, Amodeo, Antonio, Martens, Thomas, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike S., Loforte, Antonio, Pace Napoleone, Carlo, Nemec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuriy, Ramjankhan, Faiz, Sandica, Eugen, Sliwka, Joanna, Stiller, Brigitte, Kadner, Alexander, Franceschini, Alessio, Thiruchelvam, Timothy, Zimpfer, Daniel, Berger, Felix, Davies, Ben, Dashkevich, Alexey, Stark, Christoffer, Meyns, Bart, de By, Theo M.M.H., and Miera, Oliver

Published
2024

11. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): fourth Paediatric EUROMACS (Paedi-EUROMACS) report.

Author

Rohde, Sofie, Puyvelde, Joeri van, Veen, Kevin M, Schweiger, Martin, Biermann, Daniel, Amodeo, Antonio, Martens, Thomas, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike S, Loforte, Antonio, Napoleone, Carlo Pace, Nemec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuriy, and Ramjankhan, Faiz

Subjects
ARTIFICIAL blood circulation, PULSATILE flow, STROKE, PROPORTIONAL hazards models, CONGENITAL heart disease
Abstract

OBJECTIVES The use of ventricular assist devices (VADs) in children is increasing. However, absolute numbers in individual centres and countries remain small. Collaborative efforts such as the Paedi-European Registry for Patients with Mechanical Circulatory Support (EUROMACS) are therefore essential for combining international experience with paediatric VADs. Our goal was to present the results from the fourth Paedi-EUROMACS report. METHODS All paediatric (<19 years) patients from the EUROMACS database supported by a VAD were included. Patients were stratified into a congenital heart disease (CHD) group and a group with a non-congenital aetiology. End points included mortality, a transplant and recovery. Cox proportional hazard models were used to explore associated factors for mortality, cerebrovascular accident and pump thrombosis. RESULTS A total of 590 primary implants were included. The congenital group was significantly younger (2.5 vs 8.0 years, respectively, P  < 0.001) and was more commonly supported by a pulsatile flow device (73.5% vs 59.9%, P  < 0.001). Mortality was significantly higher in the congenital group (30.8% vs 20.4%, P  = 0.009) than in the non-congenital group. However, in multivariable analyses, CHD was not significantly associated with mortality [hazard ratio (HR) 1.285; confidence interval (CI) 0.8111–2.036, P  = 0.740]. Pump thrombosis was the most frequently reported adverse event (377 events in 132 patients; 0.925 events per patient-year) and was significantly associated with body surface area (HR 0.524, CI 0.333–0.823, P  = 0.005), CHD (HR 1.641, CI 1.054–2.555, P  = 0.028) and pulsatile flow support (HR 2.345, CI 1.406–3.910, P  = 0.001) in multivariable analyses. CONCLUSIONS This fourth Paedi-EUROMACS report highlights the increasing use of paediatric VADs. The patient populations with congenital and non-congenital aetiologies exhibit distinct characteristics and clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Effects of cardiac rehabilitation on functional capacity, psychological symptoms and quality of life in patients with left ventricular assist device.

Author

Çınar, Ece, Üzümcügil, Hale, Çapacı, Kazım, Engin, Çağatay, Yağdı, Tahir, Özbaran, Mustafa, Zoghi, Mehdi, and Nalbantgil, Sanem

Subjects
CARDIAC rehabilitation, QUALITY of life, LEFT heart ventricle, OXYGEN consumption, ANXIETY
Abstract

Copyright of Ege Journal of Medicine is the property of Ege University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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19. Cerebrovascular accidents in paediatric patients supported by the Berlin Heart EXCOR

Author

Rohde, Sofie, primary, Sandica, Eugen, additional, Veen, Kevin, additional, Miera, Oliver, additional, Amodeo, Antonio, additional, Napoleone, Carlo Pace, additional, Özbaran, Mustafa, additional, Sliwka, Joanna, additional, Thiruchelvam, Timothy, additional, Zimpfer, Daniel, additional, Schubert, Stephan, additional, Bogers, Ad J J C, additional, and de By, Theo M M H, additional

Published
2022
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20. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): third Paediatric (Paedi-EUROMACS) report

Author

de By, Theo M M H, primary, Schweiger, Martin, additional, Hussain, Hina, additional, Amodeo, Antonio, additional, Martens, Thomas, additional, Bogers, Ad J J C, additional, Damman, Kevin, additional, Gollmnan-Tepeköylü, Can, additional, Hulman, Michael, additional, Iacovoni, Attilio, additional, Krämer, Ulrike, additional, Loforte, Antonio, additional, Napoleone, Carlo Pace, additional, Němec, Petr, additional, Netuka, Ivan, additional, Özbaran, Mustafa, additional, Polo, Luz, additional, Pya, Yuri, additional, Ramjankhan, Faiz, additional, Sandica, Eugen, additional, Sliwka, Joanna, additional, Stiller, Brigitte, additional, Kadner, Alexander, additional, Franceschini, Alessio, additional, Thiruchelvam, Timothy, additional, Zimpfer, Daniel, additional, Meyns, Bart, additional, Berger, Felix, additional, and Miera, Oliver, additional

Published
2022
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22. The European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery:third report

Author

De By, Theo M. M. H., Schoenrath, Felix, Veen, Kevin M., Mohacsi, Paul, Stein, Julia, Alkhamees, Khalid M. M., Anastasiadis, Kyriakos, Berhnardt, Alexander, Beyersdorf, Friedhelm, Caliskan, Kadir, Reineke, David, Damman, Kevin, Fiane, Arnt, Gkouziouta, Angeliki, Gollmann-Tepeköylü, Can, Gustafsson, Finn, Hulman, Michal, Iacovoni, Attilio, Loforte, Antonio, Merkely, Bela, Musumeci, Francesco, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Potapov, Evgenij, Pya, Yuri, Rábago, Gregorio, Ramjankhan, Faiz, Reichenspurner, Hermann, Saeed, Diyar, Sandoval, Elena, Stockman, Bernard, Vanderheyden, Marc, Tops, Laurens, Wahlers, Thorsten, Zembala, Michael, Zimpfer, Daniel, Carrel, Thierry, Gummert, Jan, Meyns, Bart, De By, Theo M. M. H., Schoenrath, Felix, Veen, Kevin M., Mohacsi, Paul, Stein, Julia, Alkhamees, Khalid M. M., Anastasiadis, Kyriakos, Berhnardt, Alexander, Beyersdorf, Friedhelm, Caliskan, Kadir, Reineke, David, Damman, Kevin, Fiane, Arnt, Gkouziouta, Angeliki, Gollmann-Tepeköylü, Can, Gustafsson, Finn, Hulman, Michal, Iacovoni, Attilio, Loforte, Antonio, Merkely, Bela, Musumeci, Francesco, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Potapov, Evgenij, Pya, Yuri, Rábago, Gregorio, Ramjankhan, Faiz, Reichenspurner, Hermann, Saeed, Diyar, Sandoval, Elena, Stockman, Bernard, Vanderheyden, Marc, Tops, Laurens, Wahlers, Thorsten, Zembala, Michael, Zimpfer, Daniel, Carrel, Thierry, Gummert, Jan, and Meyns, Bart

Abstract

OBJECTIVES: In the third report of the European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery, outcomes of patients receiving mechanical circulatory support are reviewed in relation to implant era. METHODS: Procedures in adult patients (January 2011-June 2020) were included. Patients from centres with <60% follow-ups completed were excluded. Outcomes were stratified into 3 eras (2011-2013, 2014-2017 and 2018-2020). Adverse event rates (AERs) were calculated and stratified into early phase (<3 months) and late phase (>3 months). Risk factors for death were explored using univariable Cox regression with a stepwise time-varying hazard ratio (<3 vs >3 months). RESULTS: In total, 4834 procedures in 4486 individual patients (72 hospitals) were included, with a median follow-up of 1.1 (interquartile range: 0.3-2.6) years. The annual number of implants (range: 346-600) did not significantly change (P = 0.41). Both Interagency Registry for Mechanically Assisted Circulatory Support class (classes 4-7: 23, 25 and 33%; P < 0.001) and in-hospital deaths (18.5, 17.2 and 11.2; P < 0.001) decreased significantly between eras. Overall, mortality, transplants and the probability of weaning were 55, 25 and 2% at 5 years after the implant, respectively. Major infections were mainly noted early after the implant occurred (AER<3 months: 1.44 vs AER>3 months: 0.45). Bilirubin and creatinine levels were significant risk factors in the early phase but not in the late phase after the implant. CONCLUSIONS: In its 10 years of existence, EUROMACS has become a point of reference enabling benchmarking and outcome monitoring. Patient characteristics and outcomes changed between implant eras. In addition, both occurrence of outcomes and risk factor weights are time dependent.

Published
2022

23. The European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery: third report

Author

CTC, Circulatory Health, de By, Theo M M H, Schoenrath, Felix, Veen, Kevin M, Mohacsi, Paul, Stein, Julia, Alkhamees, Khalid M M, Anastasiadis, Kyriakos, Berhnardt, Alexander, Beyersdorf, Friedhelm, Caliskan, Kadir, Reineke, David, Damman, Kevin, Fiane, Arnt, Gkouziouta, Angeliki, Gollmann-Tepeköylü, Can, Gustafsson, Finn, Hulman, Michal, Iacovoni, Attilio, Loforte, Antonio, Merkely, Bela, Musumeci, Francesco, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Potapov, Evgenij, Pya, Yuri, Rábago, Gregorio, Ramjankhan, Faiz, Reichenspurner, Hermann, Saeed, Diyar, Sandoval, Elena, Stockman, Bernard, Vanderheyden, Marc, Tops, Laurens, Wahlers, Thorsten, Zembala, Michael, Zimpfer, Daniel, Carrel, Thierry, Gummert, Jan, Meyns, Bart, CTC, Circulatory Health, de By, Theo M M H, Schoenrath, Felix, Veen, Kevin M, Mohacsi, Paul, Stein, Julia, Alkhamees, Khalid M M, Anastasiadis, Kyriakos, Berhnardt, Alexander, Beyersdorf, Friedhelm, Caliskan, Kadir, Reineke, David, Damman, Kevin, Fiane, Arnt, Gkouziouta, Angeliki, Gollmann-Tepeköylü, Can, Gustafsson, Finn, Hulman, Michal, Iacovoni, Attilio, Loforte, Antonio, Merkely, Bela, Musumeci, Francesco, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Potapov, Evgenij, Pya, Yuri, Rábago, Gregorio, Ramjankhan, Faiz, Reichenspurner, Hermann, Saeed, Diyar, Sandoval, Elena, Stockman, Bernard, Vanderheyden, Marc, Tops, Laurens, Wahlers, Thorsten, Zembala, Michael, Zimpfer, Daniel, Carrel, Thierry, Gummert, Jan, and Meyns, Bart

Published
2022

24. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): third Paediatric (Paedi-EUROMACS) report

Author

CTC, Circulatory Health, de By, Theo M M H, Schweiger, Martin, Hussain, Hina, Amodeo, Antonio, Martens, Thomas, Bogers, Ad J J C, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike, Loforte, Antonio, Napoleone, Carlo Pace, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuri, Ramjankhan, Faiz, Sandica, Eugen, Sliwka, Joanna, Stiller, Brigitte, Kadner, Alexander, Franceschini, Alessio, Thiruchelvam, Timothy, Zimpfer, Daniel, Meyns, Bart, Berger, Felix, Miera, Oliver, CTC, Circulatory Health, de By, Theo M M H, Schweiger, Martin, Hussain, Hina, Amodeo, Antonio, Martens, Thomas, Bogers, Ad J J C, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike, Loforte, Antonio, Napoleone, Carlo Pace, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuri, Ramjankhan, Faiz, Sandica, Eugen, Sliwka, Joanna, Stiller, Brigitte, Kadner, Alexander, Franceschini, Alessio, Thiruchelvam, Timothy, Zimpfer, Daniel, Meyns, Bart, Berger, Felix, and Miera, Oliver

Published
2022

26. Switching the left and the right hearts: A novel bi-ventricle mechanical support strategy with spared native single-ventricle

Author

Şişli, Emrah, Yıldırım, Canberk, Aka, İbrahim Başar, Tuncel, Osman Nuri, Atay, Yüksel, Özbaran, Mustafa, and Pekkan, Kerem

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, Mock-up flow loops, surgical procedures, operative, Single-ventricle physiology, Congenital heart surgery, Mechanical circulatory support, Fontan circulation, cardiovascular system, Hemodynamics, Lumped parameter modelling, cardiovascular diseases, Cardiovascular circulation theory, Ventricle assist devices
Abstract

Mechanical circulatory support (MCS) is used as a bridge-to-heart transplantation for end-stage failing Fontan patients with single-ventricle (SV) circulation. Donor shortage and complexity of the single-ventricle circulation physiology demands novel circulatory support systems and alternative solutions. An out-of-the-box circulation concept in which the left and right ventricles are switched with each other inspired a novel bi-ventricle MCS configuration for the “failing” Fontan patients. In the proposed configuration, the systemic circulation is maintained by a conventional mechanical ventricle assist device while the venous circulation is delegated to the native SV. This approach spares the SV and puts it to a new use at the right-side providing the most needed venous flow pulsatility. To analyze its feasibility and performance, 8 realistic Fontan circulation scenarios have been studied via a multi-compartmental lumped parameter cardiovascular model (LPM). Model is developed specifically for simulating the SV circulation and validated against pulsatile mock-up flow loop measurements for the ideal (Fontan), failed (VD) and assisted Fontan (PVR-cmcs) scenarios. The proposed surgical configuration maintained the cardiac index (3-3.5 l/min/m2) providing a normal mean systemic arterial pressure. For a failed SV with low ejection fraction (EF=26%), representing a typical systemic failure, proposed configuration introduced a venous/pulmonary pulsatility of ∼28 mmHg and a drop of 2 mmHg in central venous pressure (CVP) with acceptable pulmonary artery pressures (17.5 mmHg). In the pulmonary vascular resistance (PVR) failure model, it provided approximately 5 mmHg drop in CVP with venous/pulmonary pulsatility reaching ∼22 mmHg. For high PVR failure case with a healthy SV (EF = 44%) pulmonary hypertension is likely to occur, indicating a need for precise functional assessment of the failed-ventricle before it is considered for the proposed arrangement. Comprehensivein vitroandin silicoresults encourage this concept as an economical alternative to the conventional bi-ventricle MCS pending animal experiments.

Published
2022
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27. The European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery: third report

Author

de By, Theo M M H, primary, Schoenrath, Felix, additional, Veen, Kevin M, additional, Mohacsi, Paul, additional, Stein, Julia, additional, Alkhamees, Khalid M M, additional, Anastasiadis, Kyriakos, additional, Berhnardt, Alexander, additional, Beyersdorf, Friedhelm, additional, Caliskan, Kadir, additional, Reineke, David, additional, Damman, Kevin, additional, Fiane, Arnt, additional, Gkouziouta, Angeliki, additional, Gollmann-Tepeköylü, Can, additional, Gustafsson, Finn, additional, Hulman, Michal, additional, Iacovoni, Attilio, additional, Loforte, Antonio, additional, Merkely, Bela, additional, Musumeci, Francesco, additional, Němec, Petr, additional, Netuka, Ivan, additional, Özbaran, Mustafa, additional, Potapov, Evgenij, additional, Pya, Yuri, additional, Rábago, Gregorio, additional, Ramjankhan, Faiz, additional, Reichenspurner, Hermann, additional, Saeed, Diyar, additional, Sandoval, Elena, additional, Stockman, Bernard, additional, Vanderheyden, Marc, additional, Tops, Laurens, additional, Wahlers, Thorsten, additional, Zembala, Michael, additional, Zimpfer, Daniel, additional, Carrel, Thierry, additional, Gummert, Jan, additional, and Meyns, Bart, additional

Published
2022
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29. ISHLT consensus statement for the selection and management of pediatric and congenital heart disease patients on ventricular assist devices Endorsed by the American Heart Association

Author

Lorts, Angela, primary, Conway, Jennifer, additional, Schweiger, Martin, additional, Adachi, Iki, additional, Amdani, Shahnawaz, additional, Auerbach, Scott R., additional, Barr, Charlotte, additional, Bleiweis, Mark S., additional, Blume, Elizabeth D., additional, Burstein, Danielle S., additional, Cedars, Ari, additional, Chen, Sharon, additional, Cousino-Hood, Melissa K., additional, Daly, Kevin P., additional, Danziger-Isakov, Lara A., additional, Dubyk, Nicole, additional, Eastaugh, Lucas, additional, Friedland-Little, Joshua, additional, Gajarski, Robert, additional, Hasan, Asif, additional, Hawkins, Beth, additional, Jeewa, Aamir, additional, Kindel, Steven J., additional, Kogaki, Shigetoyo, additional, Lantz, Jodie, additional, Law, Sabrina P., additional, Maeda, Katsuhide, additional, Mathew, Jacob, additional, May, Lindsay J., additional, Miera, Oliver, additional, Murray, Jenna, additional, Niebler, Robert A., additional, O'Connor, Matthew J., additional, Özbaran, Mustafa, additional, Peng, David M., additional, Philip, Joseph, additional, Reardon, Leigh Christopher, additional, Rosenthal, David N., additional, Rossano, Joseph, additional, Salazar, Leonardo, additional, Schumacher, Kurt R., additional, Simpson, Kathleen E., additional, Stiller, Brigitte, additional, Sutcliffe, David L., additional, Tunuguntla, Hari, additional, VanderPluym, Christina, additional, Villa, Chet, additional, Wearden, Peter D., additional, Zafar, Farhan, additional, Zimpfer, Daniel, additional, Zinn, Matthew D., additional, Morales, Independent Reviewers: David, additional, Cowger, Jennifer, additional, Buchholz, Holger, additional, and Amodeo, Antonio, additional

Published
2021
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32. Propensity score-based analysis of long-term follow-up in patients supported with durable centrifugal left ventricular assist devices: the EUROMACS analysis

Author

CTC, Circulatory Health, Potapov, Evgenij V, Nersesian, Gaik, Lewin, Daniel, Özbaran, Mustafa, de By, Theo M M H, Stein, Julia, Pya, Yuri, Gummert, Jan, Ramjankhan, Faiz, Zembala, Michael O, Damman, Kevin, Carrel, Thierry, Meyns, Bart, Zimpfer, Daniel, Netuka, Ivan, CTC, Circulatory Health, Potapov, Evgenij V, Nersesian, Gaik, Lewin, Daniel, Özbaran, Mustafa, de By, Theo M M H, Stein, Julia, Pya, Yuri, Gummert, Jan, Ramjankhan, Faiz, Zembala, Michael O, Damman, Kevin, Carrel, Thierry, Meyns, Bart, Zimpfer, Daniel, and Netuka, Ivan

Published
2021

33. The outcome of patients with peripartum cardiomyopathy and consecutive implantation of a left ventricular assist device

Author

Djordjevic, Ilija, primary, Merkle, Julia, additional, Eghbalzadeh, Kaveh, additional, Sabashnikov, Anton, additional, Ivanov, Borko, additional, Gummert, Jan, additional, Potapov, Evgenij, additional, Schoenrath, Felix, additional, Meyns, Bart, additional, Özbaran, Mustafa, additional, By, Theo M.M.H., additional, Wahlers, Thorsten, additional, Zeriouh, Mohamed, additional, and Rahmanian, Parwis B., additional

Published
2021
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34. European Registry for Patients with Mechanical Circulatory Support (EUROMACS): third Paediatric (Paedi-EUROMACS) report.

Author

By, Theo M M H de, Schweiger, Martin, Hussain, Hina, Amodeo, Antonio, Martens, Thomas, Bogers, Ad J J C, Damman, Kevin, Gollmann-Tepeköylü, Can, Hulman, Michael, Iacovoni, Attilio, Krämer, Ulrike, Loforte, Antonio, Napoleone, Carlo Pace, Němec, Petr, Netuka, Ivan, Özbaran, Mustafa, Polo, Luz, Pya, Yuri, Ramjankhan, Faiz, and Sandica, Eugen

Subjects
ARTIFICIAL blood circulation, HEART assist devices, MEDICAL registries, CHILD patients, PEDIATRICS, CONGENITAL heart disease
Abstract

OBJECTIVES A third paediatric report has been generated from the European Registry for Patients with Mechanical Circulatory Support (EUROMACS). The purpose of EUROMACS, which is operated by the European Association for Cardio-Thoracic Surgery, is to gather data related to durable mechanical circulatory support for scientific purposes and to publish reports with respect to the course of mechanical circulatory support therapy. Since the first report issued, efforts to increase compliance and participation have been extended. Additionally, the data provided the opportunity to analyse patients of younger age and lower weight. METHODS Participating hospitals contributed pre-, peri- and long-term postoperative data on mechanical circulatory support implants to the registry. Data for all implants in paediatric patients (<19 years of age) performed from 1 January 2000 to 31 December 2020 were analysed. This report includes updates of patient characteristics, implant frequency, outcome (including mortality rates, transplants and recovery rates) as well as adverse events including neurological dysfunction, device malfunction, major infection and bleeding. RESULTS Twenty-five hospitals contributed 537 registered implants in 480 patients. The most frequent aetiology of heart failure was any form of cardiomyopathy (59%), followed by congenital heart disease and myocarditis (15% and 14%, respectively). Competing outcomes analysis revealed that a total of 86% survived to transplant or recovery or are ongoing; at the 2-year follow-up examination, 21.9% died while on support. At 12 months, 45.1% received transplants, 7.5% were weaned from their device and 20.8% died. The 3-month adverse events rate was 1.59 per patient-year for device malfunction including pump exchange, 0.7 for major bleeding, 0.78 for major infection and 0.71 for neurological events. CONCLUSIONS The overall survival rate was 79.2% at 12 months following ventricular assist device implant. The comparison of survival rates of the early and later eras shows no significant difference. A focus on specific subgroups showed that survival was less in patients of younger age (<1 year of age; P = 0.01) and lower weight (<20 kg; P = 0.015). Transplant rates at 6 months continue to be low (33.2%). [ABSTRACT FROM AUTHOR]

Published
2022
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35. Propensity score-based analysis of long-term follow-up in patients supported with durable centrifugal left ventricular assist devices: the EUROMACS analysis

Author

Potapov, Evgenij V, primary, Nersesian, Gaik, additional, Lewin, Daniel, additional, Özbaran, Mustafa, additional, de By, Theo M M H, additional, Stein, Julia, additional, Pya, Yuri, additional, Gummert, Jan, additional, Ramjankhan, Faiz, additional, Zembala, Michael O, additional, Damman, Kevin, additional, Carrel, Thierry, additional, Meyns, Bart, additional, Zimpfer, Daniel, additional, and Netuka, Ivan, additional

Published
2021
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42. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): second EUROMACS Paediatric (Paedi-EUROMACS) report

Author

de By, Theo M M H, primary, Antonides, Christiaan F J, primary, Schweiger, Martin, primary, Sliwka, Joanna, primary, Davies, Ben, primary, Berger, Felix, primary, Hübler, Michael, primary, Özbaran, Mustafa, primary, Maruszewski, Bohdan, primary, Napoleone, Carlo Pace, primary, Zimpfer, Daniel, primary, Sandica, Eugen, primary, Antretter, Herwig, primary, Meyns, Bart, primary, and Miera, Oliver, primary

Published
2020
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43. Corrigendum to: The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): first EUROMACS Paediatric (Paedi-EUROMACS) report [Eur J Cardiothorac Surg 2018;54:800–8]

Author

de By, Theo M M H, primary, Schweiger, Martin, additional, Waheed, Hina, additional, Berger, Felix, additional, Hübler, Michael, additional, Özbaran, Mustafa, additional, Maruszewski, Bohdan, additional, Pace Napoleone, Carlo, additional, Loforte, Antonio, additional, Meyns, Bart, additional, and Miera, Oliver, additional

Published
2020
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44. Sol Ventrikül Destek Cihazı Enfeksiyonlarının Değerlendirilmesi.

Author

Kahraman, Ümit, Acet, Oğuzhan, Kahraman, Hasip, Özarslan, Muhammed Alper, Kaya, Derya, Sipahi, Oğuz Reşat, Taşbakan, Meltem, Özbaran, Mustafa, Yağdı, Tahir, and Engin, Çağatay

Abstract

Copyright of Mediterranean Journal of Infection, Microbes & Antimicrobials is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

45. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Finn, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Finn

Published
2019

46. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Circulatory Health, Team Medisch, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Finn, Circulatory Health, Team Medisch, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Finn

Published
2019

47. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Potapov, Evgenij V., Antonides, Christiaan, Crespo-Leiro, María Generosa, Combes, Alain, Färber, Gloria, Hannan, Margaret M., Kukucka, Marian, De Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H., Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Fin, Potapov, Evgenij V., Antonides, Christiaan, Crespo-Leiro, María Generosa, Combes, Alain, Färber, Gloria, Hannan, Margaret M., Kukucka, Marian, De Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H., Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Fin

Abstract

[Abstract] Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many—sometimes contradictory—observations regarding patient selection, surgical techniques, perioperative management and follow-up have been published. With the growing expertise in this field, the European Association for Cardio-Thoracic Surgery (EACTS) recognized a need for a structured multidisciplinary consensus about the approach to patients with LT-MCS. However, the evidence published so far is insufficient to allow for generation of meaningful guidelines complying with EACTS requirements. Instead, the EACTS presents an expert opinion in the LT-MCS field. This expert opinion addresses patient evaluation and preoperative optimization as well as management of cardiac and non-cardiac comorbidities. Further, extensive operative implantation techniques are summarized and evaluated by leading experts, depending on both patient characteristics and device selection. The faculty recognized that postoperative management is multidisciplinary and includes aspects of intensive care unit stay, rehabilitation, ambulatory care, myocardial recovery and end-of-life care and mirrored this fact in this paper. Additionally, the opinions of experts on diagnosis and management of adverse events including bleeding, cerebrovascular accidents and device malfunction are presented. In this expert consensus, the evidence for the complete management from patient selection to end-of-life care is carefully reviewed with the aim of guiding clinicians in optimizing management of patients considered for or supported by an LT-MCS device.

Published
2019

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