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Intoduction: A severe infection such as COVID-19 may trigger a stroke. The imaging and clinical features of patients with COVID-19 are not well-defined. We aimed to analyze neuroimaging and clinical features of stroke patients with COVID-19. Methods: The demographic and clinical data of 21 stroke cases with confirmed COVID-19 (StrokeCov) between April 2020-May 2021 were collected prospectively. An experienced stroke neurologist evaluated neuroimaging findings. A control group of gender, age, and risk factors adjusted 104 stroke patients were included. Results: Mean age was 66.3 (±13.3) and 66.2 (±13) years in the StrokeCov group and control group (CG), with similar male-to-female ratios (85%) and without significant difference regarding diabetes, hypertension, hyperlipidemia, and atrial fibrillation between groups (p>0.05). Infarcts were most frequently seen in the territory of middle cerebral artery (8 patients; 40%), followed by multiple arterial territories (6 patients; 30%). Ischemic lesions were more frequently localized in both anterior and posterior vascular systems in StrokeCov group (3 patients; 15%) in comparison to CG (2 patients; 2%; p=0.02). Although, hemorrhagic transformation was observed more frequently in StrokeCov group (6 patients; 30%) than CG (11 patients; 10%; p=0.02); statistically significant difference was not seen in terms of acute and preventive treatments given to both groups. The mRS scores on discharge were worse in the StrokeCov group (p<0.00). Conclusion: Ischemic stroke lesions in StrokeCov group are more likely to be localized on multiple arterial territories and develop hemorrhagic transformation. Poor clinical outcome and in-hospital death are more common in stroke due to COVID-19. [ABSTRACT FROM AUTHOR]

Background: In this study, we aimed to outline the neuropsychiatric consequences of primary progressive aphasia (PPA) and to understand how neuropsychiatric symptomatology affects distress in caregivers. Methods: The Neuropsychiatric Inventory (NPI) including the distress index (NPI‐Distress) was used. Additional information about the caregiver burden was obtained using Zarit Burden Interview (ZBI). NPI, NPI‐Distress, and ZBI data from 17 patients with a clinical diagnosis of PPA were compared with 10 stroke aphasia patients. Neuropsychiatric symptomatology was investigated based on three clusters; Mood, Frontal/Comportmental, and Psychotic/Disruptive. Additionally, the Activities of Daily Living Questionnaire (ADLQ) was used to outline the functional impairment. Twelve healthy controls were included to compare the neurocognitive test scores with PPA and stroke aphasia groups. Results: A greater number of neuropsychiatric symptoms were observed in the PPA group compared to the stroke aphasia group. The number of symptoms in Mood, and Frontal/Comportmental clusters were greater than the number of symptoms in Psychotic/Disruptive clusters in the PPA group, whereas no significant relationship between the number of symptoms and symptom clusters was found in the stroke aphasia group. In the PPA group, a strong correlation was found between the NPI‐Frequency × Severity scores and the NPI‐Distress scores. Moreover, the NPI‐Distress scores in the PPA group strongly correlated with the ZBI scores. Scores for anxiety, irritability/lability, and apathy had a stronger correlation with the NPI‐Distress scores compared to the other NPI symptoms. The Communication subscale was the most impaired domain in the PPA group. Travel, and Employment and Recreation subscales showed greater functional impairment in the stroke aphasia group compared to the PPA group. Conclusions: Neuropsychiatric symptoms in PPA in our study were more frequent than previously reported. Furthermore, the distress index of the NPI was not only correlated with the severity of the neuropsychiatric symptoms but also reflected the overall burden on the caregivers in the PPA group. [ABSTRACT FROM AUTHOR]

Aim: Behçet's disease (BD) is a multisystemic inflammatory disease. Cerebral venous sinus thrombosis (CVST) is the second most common form of neuro‐BD after parenchymal central nervous system involvement. The purpose of this study was to construct flow‐void probability maps of patients with CVST with and without BD to visually illustrate the impacted cerebral venous sinuses, to compare the subgroups of patients, and investigate the effect of thrombus localization on clinical findings. Methods: Seventeen patients with a diagnosis of BD‐related CVST (CVST‐BD) and 23 patients with a diagnosis of CVST related to other etiologies (CVST‐O) were included. We collected data including gender, age at onset of BD and CVST, presenting symptoms, neurological findings, and the etiology. High‐resolution magnetic resonance venographies obtained during CVST were used to mark and digitalize thrombosed areas. Thrombus probability and subtraction maps were created to reveal the differences between the subgroups. Results: Remarkably, all patients with CVST‐BD had thrombosis in the transverse sinus (TS). However, TS was affected in 73.9% of the CVST‐O patients (17/17 in CVST‐BD vs 17/23 in CVST‐O, P =.03). Thrombosis developed mostly in the superior sagittal sinus (SSS) and TS in the CVST‐O group (11/23, 47.8% and 17/23, 73.9%, respectively). The frequency of SSS thrombosis tended to be higher in the CVST‐O (47.8% vs 23.5%, P =.19). Conclusion: Venous infarction and hemorrhage were less common in patients with CVST‐BD. The only clinical symptom in most of the CSVT patients with BD was headache due to elevated intracranial pressure. TS thrombosis was more common in patients with BD. [ABSTRACT FROM AUTHOR]

Copyright of Archives of Neuropsychiatry / Nöropsikiyatri Arşivi is the property of Turkish Association of Neuropsychiatry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Neurology / Turk Noroloji Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article offers information on the public health challenges faced by the Covid-19 pandemic, along with increase number of stroke incident amid the pandemic. It mentions the evaluation of frequency of stroke in the pandemic era through several perspectives including for the general population and in cases diagnosed with Covid-19.

Posterior reversible encephalopathy syndrome (PRES), is a group of disorders which may present with headache, seizures, visual changes, altered mental status or focal neurological deficits. Many different conditions and diseases, which include tacrolimus treatment, may cause this syndrome. We present a 55 year old woman presented with PRES possibly due to tacrolimus treatment for liver transplantation. The patient stabilized after tacrolimus dose was decreased, and antihypertensive and antiepileptic treatments were started. PRES is one of the neurological complications developing after solid organ transplantation. Early diagnosis and treatment is important for the patient's life as these patients are immunsuppressive and prone to many complications of transplantation. Here we present a case of PRES, possibly due to tacrolimus use after a living donor liver transplantation and discuss briefly the possible mechanisms of PRES. [ABSTRACT FROM AUTHOR]