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Objective: Hydatid disease is an important health problem due to being endemic and progressive, and having rare spontaneous regression. In this study, we aimed to evaluate the cases in which a single-stage transthoracic surgery was applied for simultaneous right lung and liver hydatid disease, and outcomes and value of this approach. Materials and Methods: In our hospital, a single-stage transthoracic surgery was applied for simultaneous right lung and liver hydatid disease in 200 patients between 1994 and 2006. Age, sex, symptoms and presentations, operative approaches, postoperative morbidity and mortality, and follow-up of the patients results were evaluated. Results: A right thoracotomy was performed in all patients. First the lung cysts and later -after opening the diaphragma- liver cysts were resected. Of the 200 operated patiens, 97 were male and 103 were female and mean age was 28.2. While cough and chest pain were the most common symptoms, 16 patients were asymptomatic. Excessive bile drainage in 5 patients and bronchobiliary fistula in 3 patients were observed in postoperative period. These patients were managed with nasoduodenobiliary drainage. No mortality was encountered. Conclusion: A transdiaphragmatic liver cyst management with lung surgery, is a reliable and effective method in patients with simultaneous right lung and subdiaphragmatic liver hydatid disease patients. [ABSTRACT FROM AUTHOR]