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3 results on '"[Ubago-Guisado,E"'

1. Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review

Author

Ubago-Guisado, Esther, Rodríguez-Barranco, Miguel, Ching-López, Ana, Petrova, Dafina, Molina-Montes, Esther, Amiano, Pilar, Barricarte-Gurrea, Aurelio, Chirlaque, María-Dolores, Agudo, Antonio, Sánchez, María-José, [Ubago-Guisado,E, Rodríguez-Barranco,M, Ching-López,A, Petrova,D, Sánchez,MJ] Cancer Registry of Granada, Escuela Andaluza de Salud Pública, Granada, Spain. [Ubago-Guisado,E, Molina-Montes,E, Amiano,P, Barricarte-Gurrea,A, Chirlaque,MD, Sánchez,MJ] Epidemiology and Control of Chronic Diseases, CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. [Ubago-Guisado,E, Sánchez,MJ] Cancer Epidemiology Group, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. [Petrova,D] Department of Experimental Psychology, Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, Granada, Spain. [Molina-Montes,E] Department of Nutrition and Food Science, Campus of Cartuja, University of Granada, Granada, Spain. [Molina-Montes,E] Institute of Nutrition and Food Technology (INYTA) ‘José Mataix’, Biomedical Research Centre, University of Granada, Granada, Spain. [Amiano,P] Public Health Division of Gipuzkoa, BioDonostia Research Institute, Donostia-San Sebastian, Spain. [Barricarte-Gurrea,A] Navarra Public Health Institute, Pamplona, Spain. [Barricarte-Gurrea,A] Navarra Institute for Health Research (IdiSNA), Pamplona, Spain. [Chirlaque,MD] Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia University, Murcia, Spain. [Agudo,A] Unit of Nutrition and Cancer, Catalan Institute of Oncology, L’Hospitalet de Llobregat, Spain. [Agudo,A] Nutrition and Cancer Group, Epidemiology, Public Health, Cancer Prevention and Palliative Care Program, Bellvitge Biomedical Research Institute—IDIBELL, L’Hospitalet de Llobregat, Spain. [Sánchez,MJ] Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain., and E.U.-G. is supported by the Programa Operativo Fondo Social Europeo (FSE) de Andalucía (2014–2020) and Junta de Andalucía (reference DOC_01618).

Subjects
Metaanalisis, Frutas, Meat, Neoplasias de la próstata, Neoplasias pulmonares, Etanol, Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms [Medical Subject Headings], Carne, Fruits, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Ingestión de alimentos, Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms [Medical Subject Headings], Breast cancer, Neoplasias colorrectales, Vegetables, Prospective Studies, Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings], Prostate cancer, Revisión sistemática, Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [Medical Subject Headings], Diseases::Neoplasms [Medical Subject Headings], Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena [Medical Subject Headings], Colorectal cancer, Fish, Verduras, Neoplasias de la mama, Intake, Geographical Locations::Geographic Locations::Europe [Medical Subject Headings], Lung cancer, Alcohol
Abstract

The European Prospective Investigation into Cancer and Nutrition (EPIC) is a multicentre prospective study conducted in 23 centres in 10 European countries. Here we review the findings from EPIC on the relationship between diet-related exposures and incidence or mortality from the four most frequent cancers in the European population: colorectal, breast, lung, and prostate cancer. We conducted a systematic review following PRISMA guidelines and identified 110 high-quality studies based on the EPIC cohort. Fruit and vegetable consumption had a protective effect against colorectal, breast, and lung cancer, whereas only fruit had a protective effect against prostate cancer. A higher consumption of fish and lower consumption of red and processed meat were related with a lower risk of colorectal cancer; and higher consumption of fatty fish with lower risk of breast cancer. Calcium and yogurt intake were found to protect against colorectal and prostate cancer. Alcohol consumption increased the risk for colorectal and breast cancer. Finally, adherence to the Mediterranean diet emerged as a protective factor for colorectal and breast cancer. The EPIC study results are in agreement with the latest evidence from leading authorities on cancer prevention and help to inform public prevention policies and strategies. Yes

Published
2021

2. 3D DXA Hip Differences in Patients with Acromegaly or Adult Growth Hormone Deficiency

Author

Esther Ubago-Guisado, Manuel Muñoz-Torres, Beatriz García-Fontana, Luis Gracia-Marco, Antonia García-Martín, Sheila González-Salvatierra, Jose J. Gil-Cosano, [Gracia-Marco,L, Ubago-Guisado,E, Gil-Cosano,JJ] PROFITH 'PROmoting FITness and Health Through Physical Activity' Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain. [Gracia-Marco,L, Ubago-Guisado,E] Instituto de Investigación Biosanitaria ibs. GRANADA, Granada, Spain. [Gonzalez-Salvatierra,S, Garcia-Martin,A, Garcia-Fontana,B, Muñoz-Torres,M] Bone Metabolic Unit, Endocrinology and Nutrition Division, University Hospital Clínico San Cecilio, Instituto de Investigación Biosanitaria de Granada (Ibs.GRANADA), Granada, Spain. [Gonzalez-Salvatierra,S, Muñoz-Torres,M] Department of Medicine, University of Granada, Granada, Spain. [Garcia-Martin,A, Muñoz-Torres,M] CIBERFES, Instituto de Salud Carlos III, Madrid, Spain. [Ubago-Guisado,E] Escuela Andaluza de Salud Pública (EASP), Granada, Spain, This research was funded by the Fondo de Investigación Sanitaria (Instituto de Salud Carlos III) with co-financing from FEDER (grant number PI18/01235), and L.G.-M. was funded by the La Caixa Foundation within the Junior Leader fellowship programme (ID 100010434, and code LCF/BQ/PR19/11700007)

Subjects
Cortical bone, Osteoporosis, lcsh:Medicine, Hormona del crecimiento, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 0302 clinical medicine, Information Science::Information Science::Computing Methodologies::Software [Medical Subject Headings], Adult growth hormone deficiency, bone QCT/microCT, Bone mineral, DXA, 0303 health sciences, General Medicine, Skeleton (computer programming), Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings], Bone QCT/microCT, medicine.anatomical_structure, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Control Groups [Medical Subject Headings], musculoskeletal diseases, medicine.medical_specialty, Diseases::Musculoskeletal Diseases::Bone Diseases::Bone Diseases, Endocrine::Acromegaly [Medical Subject Headings], Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur [Medical Subject Headings], 030209 endocrinology & metabolism, Diseases::Musculoskeletal Diseases::Bone Diseases::Bone Diseases, Metabolic::Osteoporosis [Medical Subject Headings], Acromegalia, Article, 03 medical and health sciences, Internal medicine, Acromegaly, medicine, Persons::Persons::Age Groups::Adult [Medical Subject Headings], Growth hormone, 030304 developmental biology, Femoral neck, Absorciometría de fotón, Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings], Trochanter, Bone modelling and remodelling, business.industry, lcsh:R, medicine.disease, bone modelling and remodelling, osteoporosis, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones [Medical Subject Headings], Endocrinology, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones::Pituitary Hormones, Anterior::Growth Hormone [Medical Subject Headings], Hueso cortical, Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur::Femur Neck [Medical Subject Headings], business, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Radiography::Absorptiometry, Photon [Medical Subject Headings]
Abstract

The skeleton is regulated by and responds to pituitary hormones, especially when the circulating levels are perturbed in disease. This study aims to analyse the between-group differences in 3D dual-energy X-ray absorptiometry (DXA) parameters at the hip site among patients with acromegaly or adult growth hormone deficiency (AGHD) and a healthy control group. The current cross-sectional study includes data for 67 adults, 20 with acromegaly, 14 with AGHD and 33 healthy controls. We obtained the areal bone mineral density (aBMD) outcomes using DXA and cortical and trabecular parameters using 3D-DXA software (3D-SHAPER). The mean-adjusted 3D-DXA parameters did not differ between acromegaly patients and the controls (p &gt, 0.05), however, we found cortical bone impairment (−7.3% to −8.4%, effect size (ES) = 0.78) in AGHD patients (p &lt, 0.05). Differences in the cortical bone parameters were more evident when comparing AGHD patients (−8.5% to −16.2%, ES = 1.22 to 1.24) with acromegaly patients (p &lt, 0.05). In brief, the 3D mapping highlighted the trochanter as the site with greater cortical bone differences between acromegaly patients and the controls. Overall, AGHD patients displayed lower cortical parameters at the trochanter, femoral neck and intertrochanter compared to the controls and acromegaly patients. To sum up, 3D-DXA provided useful information about the characteristics of bone involvement in growth hormone (GH)-related disorders. Patients with AGHD showed distinct involvement of the cortical structure.

Published
2021
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3. The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial

Author

Francisco Jesus Llorente-Cantarero, Manuel Arroyo-Morales, Maria C. Vicho-González, Maria J. Ortega-Acosta, Francisco B. Ortega, Luis Gracia-Marco, Dimitris Vlachopoulos, Vicente Martínez-Vizcaíno, Ana I. Benito-Bernal, Manuel Muñoz-Torres, Esther Ubago-Guisado, Idoia Labayen, Jonatan R. Ruiz, Juan F. Pascual-Gázquez, Maria Elena Mateos, Maria J. Sánchez, Jose J. Gil-Cosano, Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa. ISFOOD - Institute for Innovation and Sustainable Development in Food Chain, Universidad Pública de Navarra. Departamento de Ciencias de la Salud, Nafarroako Unibertsitate Publikoa. Osasun Zientziak Saila, [Gil-Cosano,JJ, Ubago-Guisado,E, Ortega,FB, Ruiz,JR, Gracia-Marco,L] PROFITH 'PROmoting FITness and Health through Physical Activity' Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, Spain. [Sánchez,MJ] Andalusian School of Health (EASP), Granada, Spain. [Sánchez,MJ] Instituto de Investigación Biosanitaria Ibs.GRANADA, Granada, Spain. [Sánchez,MJ] CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. [Sánchez,MJ] Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain. [Ortega-Acosta,MJ, Pascual-Gázquez,JF] Servicio de Pediatría y Oncohematología Pediátricas, Hospital Universitario Virgen de las Nieves, Granada, Spain. [Mateos,ME, Vicho-González,MC] Pediatric Oncology Unit, Department of Pediatrics, Reina Sofia University Hospital, Córdoba, Spain. [Mateos,ME, Llorente-Cantarero,FJ] Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Córdoba, Spain. [Benito-Bernal,AI] Hospital Infantil Universitario Niño Jesús, Madrid, Spain. [Llorente-Cantarero,FJ] CIBEROBN, (Physiopathology of Obesity and Nutrition) Institute of Health Carlos III (ISCIII), Madrid, Spain. [Llorente-Cantarero,FJ] Department of Specific Didactics, Faculty of Education, University of Córdoba, Córdoba, Spain. [Labayen,I] Institute for Innovation and Sustainable Development in Food Chain (IS-FOOD), Navarra’s Health Research Institute (IdiSNA), Department of Health Sciences, Public University of Navarra, Pamplona, Navarra, Spain. [Martinez-Vizcaino,V] Universidad de Castilla-La Mancha, Health and Social Research Center, Cuenca, Spain. [Martinez-Vizcaino,V] Faculty of Health Sciences, Universidad Autónoma de Chile, Talca, Chile. [Vlachopoulos,D] Children’s Health and Exercise Research Centre, Sport and Health Sciences, University of Exeter, Exeter, UK. [Arroyo-Morales, M] Biohealth Research Institute in Granada (ibs.GRANADA), Granada, Spain. [Arroyo-Morales, M] Department of Physiotherapy, University of Granada, Granada, Spain. [Arroyo-Morales, M] 'Cuídate' Support Unit for Oncology Patients (UAPO), Sport and Health University Research Institute (iMUDS), Granada, Spain. [Muñoz-Torres,M] Bone Metabolic Unit, Endocrinology and Nutrition Division, Hospital Universitario San Cecilio, Instituto de Investigación Biosanitaria de Granada (Ibs.GRANADA), Granada, Spain. [Muñoz-Torres,M] CIBERFES, Instituto de Salud Carlos III, Madrid, Spain. [Muñoz-Torres,M] Department of Medicine, Universidad de Granada, Granada, Spain., The iBoneFIT project is funded by a fellowship from 'la Caixa' Foundation (ID 100010434). The fellowship code is LCF/BQ/PR19/11700007. This study has been partially supported by the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence, and Unit of Excellence on Exercise and Health (UCEES), and by the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades and European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR. The funders had no role in the design of this study, in the collection, analyses or interpretation of the data, in the writing of the manuscript or in the decision to submit the manuscript for publication.

Subjects
Male, Calidad de vida, Physical fitness, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Design [Medical Subject Headings], law.invention, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Study Protocol, 0302 clinical medicine, Quality of life, Randomized controlled trial, Cancer Survivors, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Physical Therapy Modalities::Exercise Therapy::Plyometric Exercise [Medical Subject Headings], law, Bone Density, Huesos, Child, Cancer, Anatomy::Musculoskeletal System::Skeleton::Bone and Bones [Medical Subject Headings], education.field_of_study, lcsh:Public aspects of medicine, Pediatría, Telemedicina, Diseases::Neoplasms [Medical Subject Headings], Neoplasias, Telemedicine, Exercise Therapy, Research Design, Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Quality of Life [Medical Subject Headings], Female, Persons::Persons::Patients::Survivors [Medical Subject Headings], Survivor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Physical Therapy Modalities::Exercise Therapy [Medical Subject Headings], Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Program Evaluation [Medical Subject Headings], Plyometric exercise, medicine.medical_specialty, Adolescent, Population, Check Tags::Male [Medical Subject Headings], 030209 endocrinology & metabolism, Persons::Persons::Age Groups::Adolescent [Medical Subject Headings], Sobrevivientes, Information Science::Information Science::Communications Media::Telecommunications::Telemedicine [Medical Subject Headings], 03 medical and health sciences, Trabecular bone score, medicine, Humans, Persons::Persons::Age Groups::Child [Medical Subject Headings], education, Bone, Ejercicio pliométrico, Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings], business.industry, Public health, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, Paediatrics, 030229 sport sciences, Anthropometry, Mental health, Check Tags::Female [Medical Subject Headings], Physical therapy, business, Program Evaluation
Abstract

Background: New approaches on paediatric cancer treatment aim to maintain long-term health. As a result of radiotherapy, chemotherapy or surgery, paediatric cancer survivors tend to suffer from any chronic health condition. Endocrine dysfunction represents one of the most common issues and affects bone health. Exercise is key for bone mass accrual during growth, specifically plyometric jump training. The iBoneFIT study will investigate the effect of a 9-month online exercise programme on bone health in paediatric cancer survivors. This study will also examine the effect of the intervention on body composition, physical fitness, physical activity, calcium intake, vitamin D, blood samples quality of life and mental health. Methods: A minimum of 116 participants aged 6 to 18 years will be randomized into an intervention (n = 58) or control group (n = 58). The intervention group will receive an online exercise programme and diet counselling on calcium and vitamin D. In addition, five behaviour change techniques and a gamification design will be implemented in order to increase the interest of this non-game programme. The control group will only receive diet counselling. Participants will be assessed on 3 occasions: 1) at baseline; 2) after the 9 months of the intervention; 3) 4 months following the intervention. The primary outcome will be determined by dual energy X-ray absorptiometry (DXA) and the hip structural analysis, trabecular bone score and 3D-DXA softwares. Secondary outcomes will include anthropometry, body composition, physical fitness, physical activity, calcium and vitamin D intake, blood samples, quality of life and mental health., La Caixa Foundation 100010434 LCF/BQ/PR19/11700007, University of Granada, Plan Propio de Investigacion 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES), Junta de Andalucía SOMM17/6107/UGR, European Union (EU) SOMM17/6107/UGR

Published
2020

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