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How can a critic account for a perceived resemblance between texts that are not related by influence? The present article examines how this question was answered by Tsubouchi Shōyō, a key figure in the early history of the academic discipline of comparative literature in Japan. In 1890 or 1891, Shōyō lectured on a then-new field of inquiry: hishō (or hikaku) bungaku. His lectures were avowedly a free adaptation of Hutcheson Macaulay Posnett's Comparative Literature (1886). Shōyō was among the first generation of Japanese to receive an education in European literatures and undertook pioneering work in what might be called "east-west" criticism, uncovering many similarities between works in Japanese and English. But since there had been almost no exchange between Japanese literature and European literatures for centuries, accounting for those similarities posed a challenge. This might explain why Shōyō found Posnett's methodology valuable: Posnett applied social science to the study of literature as a way to supersede criticism based on identifiable literary influence. Shōyō's own comparative criticism, however, differed from Posnett's: while Posnett maintained that resemblances, even between notionally unrelated texts, must be referable to some commonality of context, Shōyō maintained that cross-textual similarity could arise purely by accident. [ABSTRACT FROM AUTHOR]

The conservation of the main protease in viral genomes, combined with the absence of a homologous protease in humans, makes this enzyme family an ideal target for developing broad-spectrum antiviral drugs with minimized host toxicity. GC-376, a peptidomimetic 3CL protease inhibitor, has shown significant efficacy against coronaviruses. Recently, a GC-376-based PROTAC was developed to target and induce the proteasome-mediated degradation of the dimeric SARS-CoV-2 3CLPro protein. Extending this approach, the current study investigates the application of the GC-376 PROTAC to the 3CPro protease of enteroviruses, specifically characterizing its interaction with CVB3 3CPro through X-ray crystallography, NMR (Nuclear Magnetic Resonance) and biochemical techniques. The crystal structure of CVB3 3CPro bound to the GC-376 PROTAC precursor was obtained at 1.9 Å resolution. The crystallographic data show that there are some changes between the binding of CVB3 3CPro and SARS-CoV-2 3CLPro, but the overall similarity is strong (RMSD on C-alpha 0.3 Å). The most notable variation is the orientation of the benzyloxycarbonyl group of GC-376 with the S4 subsite of the proteases. NMR backbone assignment of CVB3 3CPro bound and unbound to the GC-376 PROTAC precursor (80% and 97%, respectively) was obtained. This information complemented the investigation, by NMR, of the interaction of CVB3 3CPro with the GC-376 PROTAC, and its precursor allows us to define that the GC-376 PROTAC binds to CVB3 3CPro in a mode very similar to that of the precursor. The NMR relaxation data indicate that a quench of dynamics of a large part of the protein backbone involving the substrate-binding site and surrounding regions occurs upon GC-376 PROTAC precursor binding. This suggests that the substrate cavity, by sampling different backbone conformations in the absence of the substrate, is able to select the suitable one necessary to covalently bind the substrate, this being the latter reaction, which is the fundamental step required to functionally activate the enzymatic reaction. The inhibition activity assay showed inhibition potency in the micromolar range for GC-376 PROTAC and its precursor. Overall, we can conclude that the GC-376 PROTAC fits well within the binding sites of both proteases, demonstrating its potential as a broad-spectrum antiviral agent. [ABSTRACT FROM AUTHOR]

Researchers have proposed the dynamic heterogeneous redundancy (DHR) architecture, which integrates dynamic, heterogeneous, redundant, and closed-loop feedback elements into the system, to fortify the reliability of the railway passenger service system (RPSS). However, there are at least two weaknesses with the common DHR architectures: (1) they need system nodes with enough computing and storage resources; (2) they have hardly considered the reliability of DHR architecture. To this end, this paper proposes a double-layer DHR (DDHR) architecture to ensure the reliability of RPSS. This architecture introduces a set of algorithms, which are optimized co-computation and ruling weight optimization algorithms for the data processing flow of the DDHR architecture. This set improves the reliability of the DDHR architecture. For the evaluation of the reliability of DDHR architecture, this paper also proposes two metrics: (1) Dynamic available similarity metric. This metric does not rely on the overall similarity of the double-layer redundant executor sets but evaluates the similarity of their performance under the specified interaction paths within a single scheduling cycle. The smaller its similarity, the higher its reliability. (2) Scheduling cycle under dual-layer similarity threshold. This metric evaluates the reliability of the RPSS under actual conditions by setting the schedulable similarity thresholds between the same and different layers of the dual-layer redundant executives in the scheduling process. Finally, analog simulation experiments and prototype system building experiments are carried out, whose numerical experimental results show that the DDHR architecture outperforms the traditional DHR architecture in terms of reliability and performance under different redundancy and dynamically available similarity thresholds, while the algorithmic complexity and multi-tasking concurrency performance are slightly weaker than that of the DHR architecture, but can be applied to the main operations of the RPSS in general. [ABSTRACT FROM AUTHOR]

Air quality sensor (AQS) networks are useful for mapping PM 2.5 (particles with a diameter of 2.5 µm or smaller) in urban environments, but quantitative assessment of the observed spatial and temporal variation is currently underdeveloped. This study introduces a new metric – the concentration similarity index (CSI) – to facilitate a quantitative and time-averaged comparison of the concentration–time profiles of PM 2.5 measured by each sensor within an air quality sensor network. Following development on a dataset with minimal unexplained variation and robust tests, the CSI function is used to represent an unbiased and fair depiction of the air quality variation within an area covered by a monitoring network. The measurement data is used to derive a CSI value for every combination of sensor pairs in the network, yielding valuable information on spatial variation in PM 2.5. This new method is applied to two separate AQS networks, in Dungarvan and in the city of Cork, Ireland. In Dungarvan there was a lower mean CSI value (x‾CSI, Dungarvan=0.61 , x‾CSI, Cork=0.71), indicating lower overall similarity between locations in the network. In both networks, the average diurnal plots for each sensor exhibit an evening peak in PM 2.5 concentration due to emissions from residential solid-fuel burning; however, there is considerable variation in the size of this peak. Clustering techniques applied to the CSI matrices identify two different location types in each network; locations in central or residential areas that experience more pollution from solid-fuel burning and locations on the edge of the urban areas that experience cleaner air. The difference in mean PM 2.5 between these two location types was 6 µgm-3 in Dungarvan and 2 µgm-3 in Cork. Furthermore, the examination of winter and summer months (January and May) indicates that higher PM 2.5 levels during periods of increased residential solid-fuel burning act as a major driver for greater differences (lower similarity indices) between locations in both networks, with differences in mean seasonal CSI values exceeding 0.25 and differences in mean seasonal PM 2.5 exceeding 7 µgm-3. These findings underscore the importance of including wintertime PM data in analyses, as the differences between locations is enhanced during periods when solid-fuel burning activities are at a peak. Additionally, the CSI method facilitates the assessment of the representativeness of the PM 2.5 measured at regulatory air quality monitoring locations with respect to population exposure, showing here that location type is more important than physical proximity in terms of similarity and spatial representativeness assessments. Applying the CSI in this manner can allow for the placement of monitoring infrastructure to be optimised. The results indicate that the population exposure to PM 2.5 in Dungarvan is moderately represented (x‾CSI=0.63) by the current regulatory monitoring location, and the regulatory monitoring location assessed in Cork represented the city-wide PM 2.5 levels well (x‾CSI=0.76). [ABSTRACT FROM AUTHOR]

Online news article recommendations are typically of the 'more like this' type, generated by similarity functions. Across three studies, we examined the representativeness of different similarity functions for news item retrieval, by comparing them to human judgments of similarity. In Study 1 ( N = 401 ), participants assessed the overall similarity of ten randomly paired news articles on politics and compared their judgments to different feature-specific similarity functions (e.g., based on body text or images). In Study 2, we checked for domain differences in a mixed-methods survey ( N = 45 ), surfacing evidence that the effectiveness of similarity functions differs across different news categories ('Recent Events', 'Sport'). In Study 3 ( N = 173 ), we improved the design of Study 1, by controlling for how news articles were matched, differentiating between dissimilar news articles and articles that were matched on a shared topic, named entities, and/or date of publication, across 'Recent Events' and 'Sport' categories. Across all studies, we found that users mostly used text-based features (e.g., body text, title) for their similarity judgments, while BodyText:TF-IDF was found to be the most representative for their judgments. Moreover, the strength of similarity judgments by humans and similarity scores by feature-specific functions was strongly affected by how news article pairs were matched. We show that humans and similarity functions are better aligned when two news articles are more alike, such as in a news recommendation scenario. [ABSTRACT FROM AUTHOR]

Let p be an odd prime. We review the characterization of p-valued Maiorana-McFarland bent functions with the Reed-Muller and the Reed-Muller-Fourier Transforms. We show that both transforms generate the same characterization and, based on the orthogonality of vectors, we prove why this is possible. Following the Language Philosopher Ludwig von Wittgenstein we consider this as a case of Family Resemblance. [ABSTRACT FROM AUTHOR]

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While conducting phylogenetic analyses of sequence-capture data of Australian members of Asteraceae tribe Astereae, we found that Elachanthus pusillus F.Muell., Isoetopsis graminifolia Turcz. and Kippistia suaedifolia F.Muell. formed a clade with Minuria. We, therefore, conducted an analysis focused on this clade, but with replicate samples of the three smaller genera, and confirmed our results. Kippistia had been synonymised under Minuria between 1876 and 1980, when it was reinstated. Elachanthus and Isoetopsis had not previously been suggested to be part of Minuria , and, indeed, Isoetopsis had been considered so morphologically divergent that even its tribal affiliations were long controversial. However, on closer examination, Elachanthus and Isoetopsis are strikingly similar to Minuria , especially in cypsela and pappus morphology. The evolution of both genera from a common ancestor in Minuria appears plausible in the light of their overall similarity to annual species of that genus such as M. annua , their multiple uniform rows of herbaceous phyllaries with scarious margins, a pappus of scales v. the tendency of Minuria to form pappi with scale-like bases, female outer and male inner florets, and a cypsela indumentum shared with some species of Minuria. We propose the following three new combinations under Minuria : M. pusilla , M. glabra and M. graminifolia. We conducted a phylogenetic analysis of Minuria and related genera and found that Elachanthus , Isoetopsis , and Kippistia phylogenetically nested in Minuria. Before 1980, Kippistia had long been considered part of Minuria. Morphological examination showed many similarities between Eleachanthus , Isoetopsis , and annual species of Minuria. We publish new combinations for four species, synonymising the three smaller genera. (Image credit: Alexander Schmidt-Lebuhn.) This article belongs to the collection Genomics for Australian Plants. [ABSTRACT FROM AUTHOR]

Summary: We investigated arousal scoring agreement within full‐night polysomnography in a multi‐centre setting. Ten expert scorers from seven centres annotated 50 polysomnograms using the American Academy of Sleep Medicine guidelines. The agreement between arousal indexes (ArIs) was investigated using intraclass correlation coefficients (ICCs). Moreover, kappa statistics were used to evaluate the second‐by‐second agreement in whole recordings and in different sleep stages. Finally, arousal clusters, that is, periods with overlapping arousals by multiple scorers, were extracted. The overall similarity of the ArIs was fair (ICC = 0.41), varying from poor to excellent between the scorer pairs (ICC = 0.04–0.88). The ArI similarity was better in respiratory (ICC = 0.65) compared with spontaneous (ICC = 0.23) arousals. The overall second‐by‐second agreement was fair (Fleiss' kappa = 0.40), varying from poor to substantial depending on the scorer pair (Cohen's kappa = 0.07–0.68). Fleiss' kappa increased from light to deep sleep (0.45, 0.45, and 0.53 for stages N1, N2, and N3, respectively), was moderate in the rapid eye movement stage (0.48), and the lowest in the wake stage (0.25). Over a half of the arousal clusters were scored by one or two scorers, and less than a third by at least five scorers. In conclusion, the scoring agreement varied depending on the arousal type, sleep stage, and scorer pair, but was overall relatively low. The most uncertain areas were related to spontaneous arousals and arousals scored in the wake stage. These results indicate that manual arousal scoring is generally not reliable, and that changes are needed in the assessment of sleep fragmentation for clinical and research purposes. [ABSTRACT FROM AUTHOR]

This paper explores connections between theories of morality and theories of properties. It argues that (1) moral realism is in tension with predicate, class and mereological nominalism; (2) moral non-naturalism is incompatible with standard versions of resemblance nominalism, immanent realism and trope theory; and (3) the standard semantic arguments for property realism do not support moral realism. I also raise doubts about trope-theoretic explanations of moral supervenience and argue against one version of the principle that we should accept theories that maintain neutrality. [ABSTRACT FROM AUTHOR]

Contemporary action theory is generally concerned with giving theories of action ontology. In this paper, we make the novel proposal that the standard view in action theory—the Causal Theory of Action—should be recast as a “model,” akin to the models constructed and investigated by scientists. Such models often consist in fictional, hypothetical, or idealized structures, which are used to represent a target system indirectly via some resemblance relation. We argue that recasting the Causal Theory as a model can not only accomplish the goals of causal theorists, but also give the theory greater flexibility in responding to common objections. [ABSTRACT FROM AUTHOR]

Lycopene β cyclase (LCY-B) catalyzes the conversion of linear lycopene to cyclic β carotene, a crucial component of the photosynthetic machinery and a source of vitamin A for humans and animals. The gene was amplified in fragments using primers designed from conserved sequences of available nucleotide sequences from NCBI and a sequence of 1494 bp was observed upon amplification of the complete gene. The deduced amino acid sequence had a significant overall similarity with sequences of other Capsicum plants. It was observed that C. frutescens occurred in the same cluster as C. annuum and C. baccatum, while LCYB from all the other plants of the Solanaceae family were placed in one cluster signifying the conserved nature of the protein. The tertiary structure obtained from the protein was validated using the Ramachandran plot and ERRANT scores were determined. The protein function analysis gives insight into important parameters of the protein such as the number of cysteine residues, glycosylation sites, phosphorylation sites, etc. [ABSTRACT FROM AUTHOR]

Salmonella enterica serovar Infantis (S. Infantis) is a globally distributed non-typhoid serovar infecting humans and food-producing animals. Considering the zoonotic potential and public health importance of this serovar, strategies to characterizing, monitor and control this pathogen are of great importance. This study aimed to determine the genetic relatedness of 80 Brazilian S. Infantis genomes in comparison to 40 non-Brazilian genomes from 14 countries using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR–Multi-Locus Virulence Sequence Typing (CRISPR–MVLST). CRISPR spacers were searched using CRISPR-Cas++ and fimH and sseL alleles using BLAST and MEGA X. Results were analyzed using BioNumerics 7.6 in order to obtain similarity dendrograms. A total of 23 CRISPR1 and 11 CRISPR2 alleles formed by 37 and 26 types of spacers, respectively, were detected. MVLST revealed the presence of five fimH and three sseL alleles. CRISPR's similarity dendrogram showed 32 strain subtypes, with an overall similarity ≥ 78.6. The CRISPR–MVLST similarity dendrogram showed 37 subtypes, with an overall similarity ≥ 79.2. In conclusion, S. Infantis strains isolated from diverse sources in Brazil and other countries presented a high genetic similarity according to CRISPR and CRISPR–MVLST, regardless of their source, year, and/or place of isolation. These results suggest that both methods might be useful for molecular typing S. Infantis strains using WGS data. [ABSTRACT FROM AUTHOR]

Background: Baolia H.W.Kung & G.L.Chu is a monotypic genus only known in Diebu County, Gansu Province, China. Its systematic position is contradictory, and its morphoanatomical characters deviate from all other Chenopodiaceae. Recent study has regarded Baolia as a sister group to Corispermoideae. We therefore sequenced and compared the chloroplast genomes of this species, and resolved its phylogenetic position based on both chloroplast genomes and marker sequences. Results: We sequenced 18 chloroplast genomes of 16 samples from two populations of Baolia bracteata and two Corispermum species. These genomes of Baolia ranged in size from 152,499 to 152,508 bp. Simple sequence repeats (SSRs) were primarily located in the LSC region of Baolia chloroplast genomes, and most of them consisted of single nucleotide A/T repeat sequences. Notably, there were differences in the types and numbers of SSRs between the two populations of B. bracteata. Our phylogenetic analysis, based on both complete chloroplast genomes from 33 species and a combination of three markers (ITS, rbcL, and matK) from 91 species, revealed that Baolia and Corispermoideae (Agriophyllum, Anthochlamys, and Corispermum) form a well-supported clade and sister to Acroglochin. According to our molecular dating results, a major divergence event between Acroglochin, Baolia, and Corispermeae occurred during the Middle Eocene, approximately 44.49 mya. Ancestral state reconstruction analysis showed that Baolia exhibited symplesiomorphies with those found in core Corispermoideae characteristics including pericarp and seed coat. Conclusions: Comparing the chloroplast genomes of B. bracteata with those of eleven typical Chenopodioideae and Corispermoideae species, we observed a high overall similarity and a one notable noteworthy case of inversion of approximately 3,100 bp. of DNA segments only in two Atriplex and four Chenopodium species. We suggest that Corispermoideae should be considered in a broader sense, it includes Corispermeae (core Corispermoideae: Agriophyllum, Anthochlamys, and Corispermum), as well as two new monotypic tribes, Acroglochineae (Acroglochin) and Baolieae (Baolia). [ABSTRACT FROM AUTHOR]

As a new software design paradigm, microservices structure an application as a collection of services that are independently deployable and loosely coupled. A key step of migrating non‐microservices‐based systems to microservices‐based systems is the identification of microservices in the target application. Traditional approaches to identify microservices, however, usually suffer from lack of full automation and low effectiveness. This paper puts forward an expert system to identify microservices automatically from legacy systems by leveraging the similarity of RESTful APIs. The system consists of three major parts. The first part calculates the candidate topic similarity and the response message similarity of APIs, and the overall similarity is obtained through their combination. Afterwards, the second part constructs a graph of API similarities with API as the node and the overall similarity as the weight. The third part employs a graph‐based clustering algorithm to identify candidate microservices from the API similarity graph. Experiments conducted on open‐source projects demonstrate the effectiveness of our system. [ABSTRACT FROM AUTHOR]

Universals are properties that are shared by multiple objects. In classical South Asia, Brahmanical thinkers from Vyākaraṇa, Nyāya, Vaiśeṣika, and Mīmāṃsā text traditions were realists about universals, while most Buddhists were nominalists. In this paper, my aim is to reconstruct the early Nyāya-Vaiśeṣika theory of universals, with special emphasis on the arguments of the Nyāya philosopher Uddyotakara (6th century CE) against a Buddhist strand of resemblance nominalism. I show that Uddyotakara's contribution to this debate is twofold. First, he is possibly the first Naiyāyika to adopt a sparse theory of universals, a theory according to which it is necessary to posit only those universals which explain how objects resemble each other in the most fundamental or irreducible respects. On the other hand, he offers a few arguments for realism, which are explicitly motivated by a causal constraint on intentionality. [ABSTRACT FROM AUTHOR]

How did criminal bail work in the Founding era? This question has become pressing as bail, and bail reform, have attracted increasing attention, in part because history is thought to bear on the meaning of bail-related constitutional provisions. To date, however, there has been no thorough account of bail at the Founding. This Article begins to correct the deficit in our collective memory by describing bail law and practice in the Founding era, from approximately 1790 to 1810. In order to give a full account, we surveyed a wide range of materials, including Founding-era statutes, case law, legal treatises, and manuals for magistrates; and original court, jail, administrative, and justice-of-the-peace records held in archives and private collections. The historical inquiry illuminates three key facts. First, the black-letter law of bail in the Founding era was highly protective of pretrial liberty. A uniquely American framework for bail guaranteed release, in theory, for nearly all accused persons. Second, things were different on the ground. The primary records reveal that, for those who lived on the margins of society, bail practice bore little resemblance to the law on the books, and pretrial detention was routine. The third key point cuts across the law and reality of criminal bail: both in theory and in practice, the bail system was a system of unsecured pledges, not cash deposits. It operated through reputational capital, not financial capital. This fact refutes the claim, frequently advanced by opponents of contemporary bail reform, that cash bail is a timeless American tradition. The contrast between the written ideals and the actual practice of bail in the Founding era, meanwhile, highlights the difficulty of looking to the past for a determinate guide to legal meaning. [ABSTRACT FROM AUTHOR]

Air quality sensor (AQS) networks are useful for mapping PM2.5 in urban environments, but quantitative assessment of the observed spatial and temporal variation is currently under-developed. This study introduces a new metric – the Concentration Similarity Index (CSI) – to facilitate a quantitative and time-averaged comparison of the concentration‑time profiles of PM2.5 measured by each sensor within an air quality sensor network. Following development on a dataset with minimal unexplained variation and robust tests, the CSI function is ensured to represent an unbiased and fair depiction of the air quality variation within an area covered by a monitoring network. The measurement data is used to derive a CSI value for every combination of sensor pairs in the network, which can then be compared with others in the network, yielding valuable information on spatial variation in PM2.5. This new method is applied to two separate AQS networks in Dungarvan and Cork City, Ireland. Dungarvan yielded a lower mean CSI, indicating lower overall similarity between locations in the network, possibly due to the town's coastal location giving rise to higher variation within the network. In both networks, the average diurnal plots for each sensor exhibit an evening peak in PM2.5 concentration due to emissions from residential solid fuel burning, however, there is considerable variation in the size of this peak. Clustering techniques applied to the CSI matrices identify two different location types in each network; locations in central or residential areas which experience more pollution from sold fuel burning and locations on the edge of the urban areas which experience cleaner air. Furthermore, the examination of isolated data periods (January and May) indicates higher PM2.5 levels during periods of increased residential solid fuel burning act as a major driver for greater differences (lower similarity indices) between locations in both networks. Additionally, the CSI method facilitates the assessment of the representativeness of the PM2.5 measured at regulatory air quality monitoring locations with respect to population exposure, showing here that location type is more important than physical proximity in terms of similarity assessment. Applying the CSI in this manner can allow for the placement of monitoring infrastructure to be optimised. The findings of this work underscore the influence of solid fuel combustion as a local contributor to PM2.5 and the variation it can cause between the measurements at different monitoring locations in a network while also highlighting the importance of including wintertime PM data for accurate comparisons. The CSI method developed here could be a valuable tool for quantitative comparisons of air quality within a monitoring network, offering insights for further regulatory monitoring and exposure assessments. [ABSTRACT FROM AUTHOR]

The tibial organ of Chloropidae and Milichiidae flies is an obscure feature with taxonomic significance. This study provides the first in-depth investigation into the ultrastructure of the hind leg of 11 genera from all Chloropidae subfamilies using a multimodal microscopy approach. The modified dermal tissue associated with the tibial organ indicates glandular function, as evidenced by the presence of secretory vesicles containing non-proteinaceous elements, potentially indicating lipidic secretion. The overall similarity of the tibial organ between Chloropidae and Milichiidae indicates a shared homology. However, the evolutionary history of this structure is still contentious due to limitations in the phylogenetic relationships of both lineages. Moreover, our findings enable future comparative investigations of other Diptera leg organs that possess secretory ability, which could be homologous across schizophoran families, but not necessarily the organs themselves. [ABSTRACT FROM AUTHOR]

The transformation of the fore wings into strongly sclerotized protective covers (elytra) is considered a fundamental evolutionary innovation of the megadiverse order Coleoptera. Surprisingly, these multifunctional structures have been reduced in many distantly related groups of beetles. Patterns, drivers and the evolutionary implications of this modification have never been comprehensively discussed. In the present study, we surveyed the entire order Coleoptera to analyse the patterns of elytral shortening and loss, with a special focus on prevalence, forms, degree of reduction and the functional background of this significant deviation from the coleopteran ground plan. Our analysis revealed that about 20% of all extant species (roughly 88,000 out of 442,275 spp.), distributed across all four suborders, have shortened or even absent elytra. The elytral loss was more frequent within the polyphagan series Elateriformia and Staphyliniformia. Moreover, we found that elytral reduction has independently occurred multiple times in the evolutionary history of Coleoptera and that it has been driven by a wide array of selective drivers. One of the main drivers is the improved flexibility of the uncovered abdomen and the correlated increased manoeuvrability in narrow spaces, as well as the option of using the flexible abdomen as a steering organ or to facilitate mating. Another common driver is mimicry, where exposed metathoracic wings potentially improve the overall similarity to hymenopteran models. Exposure of the abdomen can facilitate the targeted release of defensive abdominal gland secretions and was most likely a crucial step towards establishing relations with social insects enhanced by chemical communication. In the Elateriformia, and rarely in other lineages, elytral loss is a consequence of paedomorphosis, related to a specific resource‐allocation strategy. In many groups of beetles with reduced elytra, alternative defensive strategies can be found. This includes, for instance, aposematic coloration, chemical defence, mimicry or bioluminescence. Direct drivers of elytral loss in many groups remain unclear, and more studies are needed to understand the evolutionary background and implications of this significant morphological modification in Coleoptera. [ABSTRACT FROM AUTHOR]

DNA methylation is an ideal trait to study the extent of the shared genetic control across ancestries, effectively providing hundreds of thousands of model molecular traits with large QTL effect sizes. We investigate cis DNAm QTLs in three European (n = 3701) and two East Asian (n = 2099) cohorts to quantify the similarities and differences in the genetic architecture across populations. We observe 80,394 associated mQTLs (62.2% of DNAm probes with significant mQTL) to be significant in both ancestries, while 28,925 mQTLs (22.4%) are identified in only a single ancestry. mQTL effect sizes are highly conserved across populations, with differences in mQTL discovery likely due to differences in allele frequency of associated variants and differing linkage disequilibrium between causal variants and assayed SNPs. This study highlights the overall similarity of genetic control across ancestries and the value of ancestral diversity in increasing the power to detect associations and enhancing fine mapping resolution. Most functional genomic resources have been based on individuals with European ancestry. Here, the authors perform DNA methylation quantitative trait locus (mQTL) analyses in 3,701 European and 2,099 East Asian individuals to identify thousands of genetic variants, a large degree of which are shared between the two populations. [ABSTRACT FROM AUTHOR]

In "Truth by Analysis: Games, Names, and Philosophy," Colin McGinn seeks to revitalize the traditional approach to conceptual analysis. He asserts that the definition of a concept involves specifying necessary and sufficient conditions for its application, a task he deems achievable. In pursuit of this goal, McGinn critiques opposing perspectives, including that of Wittgenstein. He explores various ways to define the concept of game, and at his best, he relies on Bernard Suits' definition. This paper argues that McGinn's attempts fall short and affirms the significance of Wittgenstein's insight. It critiques all definitions put forth by McGinn, particularly that of Suits, presenting counterexamples to challenge them. Furthermore, the paper uncovers deeper misconceptions underlying these criticisms: McGinn expects family resemblance to serve as both the necessary and sufficient conditions for applying a concept and perceives it as a theory explaining how concepts refer to their extensions, contrasting with Wittgenstein, who does not aim to develop a theory and does not propose family resemblance as a sufficient condition for a concept's application. [ABSTRACT FROM AUTHOR]

I propose a "Milky Way / creation hypothesis" for the elongated eastern structures in early Maya E Groups: they were modeled on the Milky Way galaxy. These architectural arrangements, beginning in the Preclassic period (c. 900 B.C.–A.D. 200) in the southern Maya Lowlands, were adopted from predecessors in the Early Preclassic neighboring Gulf Coast region. The widespread overall similarity of E Groups suggests a shared belief system centered on myths about creation, and many of the characters (e.g., Maize God) and events of creation in Maya myths are set in the Milky Way. The general north–south axial orientation of the eastern platform, frequently pivoted northeast–southwest, is proposed to be related to the rainy season position of the Milky Way overhead. E Groups were probably multifunctional ritual theaters, the eastern platforms serving as stages for nighttime performances of creation stories. Late modifications into a tripart edifice, with structures or superstructures in the center and at both ends, replicated the major asterisms of the visible galaxy and/or the creator gods. [ABSTRACT FROM AUTHOR]

This study aims to evaluate the accuracy of L-shaped reduction malarplasty with bone setback or resection on the zygoma and the mortice and tenon joint structure on the zygomatic arch under the guidance of virtual surgical planning (VSP). Adult patients with zygomatic protrusion or hypertrophy were enrolled and divided. L-shaped reduction malarplasty with or without bone resection and with the mortice and tenon joint structure on the zygomatic arch was conducted either by digital procedures comprising VSP and three-dimensional (3D) printing titanium templates (Group I) or by conventional methods (Group II). Positions of representative landmarks and superimposition models were analyzed by 3D cephalometry. Satisfaction rate and incidences of clinical complications were compared as well. Satisfactory reduction of zygomatic protrusion or hypertrophy was recognized among all 78 patients. Improved symmetry and great surgical accuracy were observed according to the cephalometry analyses. The bone segment movement of virtual plans and actual results in Group I were measured and showed no obvious difference for the inward movement (5.42 ± 0.98 mm vs. 5.33 ± 0.93 mm, P = 0.6906) and the sagittal overlap (4.77 ± 1.32 mm vs. 4.87 ± 1.21 mm, P = 0.7386) at the zygoma roots, along with the step length at the long-arm of the L-shaped osteotomy line (2.43 ± 1.11 mm vs. 2.39 ± 0.89 mm, P = 0.8665). The high resemblance between virtual plans and actual results was depicted via superimposition models. Meanwhile, a higher satisfaction rate (28 in 36, 78% vs. 20 in 42, 48%) and a lower incidence rate of complications (11 in 36, 31% vs. 21 in 42, 50%) were found in Group I. Within the limitations of the study it seems that the application of VSP in reduction malarplasty could significantly contribute to better surgical accuracy and reduced difficulties in the operation, which would be beneficial to patients with zygoma hypertrophy or prominence. [ABSTRACT FROM AUTHOR]

Johnson and Hudecki argue that Bernard Suits fails to refute Wittgenstein's 'family resemblance' view of games because Suits's account of how games begin, how they are played, and the ends they involve, fails to match basic facts of player experience. In reply, the current paper describes three keys to interpreting The Grasshopper: (1) distinguishing the four perspectives from which Suits describes games, (2) recognizing Suits' dispositional view of rule following, and (3) understanding the geometrical metaphor Suits uses to describe rules. In light of these, this paper argues that Johnson and Hudecki's critiques are either mistaken or are actually affirmations of Suits' position. [ABSTRACT FROM AUTHOR]

Using a multidisciplinary approach to understand the subsurface processes behind the formation of maar‐diatreme volcanoes is of growing interest. While geophysical characterization can visualize the diatreme and the feeding dike system beneath the volcano at a reasonable scale, such data are rare and generally unavailable. Stratigraphic‐controlled sampling and geochemical analysis of pyroclasts within the ejecta ring can, however, provide substantial information on dike evolution and the influence of the magmatic plumbing system on the growth of these volcanoes. Such investigation is presented here for the Barombi Mbo Maar (BMM), a complex maar of the Cameroon Volcanic Line (CVL) composed of a pile of tephra units linked to multiple explosive phases that were grouped into three eruptive episodes. Major and trace element compositions of lavas collected from the different eruptive units indicate that the erupted magmas at BMM consist mainly of basalt, trachybasalt and basanite, with Oceanic Island Basalts (OIB) and high μ (μ = 238U/204Pb) (HIMU) signatures. Compositional modelling suggests that partial melting occurred at different degrees in the garnet‐to‐spinel transition zone from one episode to another. The repetition of eruptions with big gaps between them, the presence of another large adjacent old maar crater next to the 2.5 km crater of the BMM, and the overall similarity in geochemical compositions from one eruption to another suggest a deep high‐productive zone in the mantle beneath the BMM. The latter productive zone was capable of generating magma batches episodically to fuel several individual monogenetic eruptions at the same location. [ABSTRACT FROM AUTHOR]

Objective: To investigate whether beta-catenin and Forkhead box protein P1 (FOXP1) play a role in pathogenesis of polypoid endometriosis (PE). Material and Method: Our study included fifteen cases of PE. Clinical findings were gathered from archived files of relevant clinics and pathology reports. All glass slides were re-examined for confirmation of the diagnosis and the detection of additional microscopic findings. An immunohistochemical examination was performed using anti beta-catenin and FOXP1 antibodies in fifteen cases of PE, and in a control group that contained nine cases of endometrial polyps (EP) and nine cases of conventional ovarian endometriosis (OE). Result: Stromal nuclear beta-catenin expression was observed in six cases in PE, five cases in EP and one case in the OE group. Stromal FOXP1 staining in PE and EP was significantly reduced as compared to OE. Five PE and two EP cases showed stromal FOXP1 staining while all the OE cases showed stromal FOXP1 staining. The Stromal FOXP1 staining was statistically significant between PE vs OE (p=0.002) and EP vs OE (p=0.023) cases. There was no difference between PE and the control cases in terms of nuclear beta-catenin staining (p=0.69). There was no correlation between these two antibodies and histologic features. Conclusion: The loss of stromal FOXP1 is another biological difference of PE and the overall similarity of expression of FOXP1 between PE and EP could be regarded as a contributing factor for polyp formation. [ABSTRACT FROM AUTHOR]

To verify the accuracy and rationality of discrete fracture network modeling, a comprehensive method for evaluating the similarity between two-dimensional fracture maps is proposed in this study. Five evaluation indicators for two-dimensional discrete fracture networks are proposed, including spacing, length, angle, position, and density of rock fractures. Based on the quantitative characteristics of each indicator, methods for evaluating data distribution similarity based on the Wasserstein distance function and matrix similarity based on vector cosine values are proposed. Considering the grouping characteristics of trace lines that are neglected in existing similarity systems, the similarity between each indicator is calculated based on the grouping matching of trace line maps. This achieves the comprehensive calculation of grouping similarity and overall similarity indicators. The importance and size effects of indicators are discussed through fracture model examples. The results show that the indicators of grouping similarity are more rigorous and suitable for engineering modeling with strict requirements compared to those for overall similarity. The proposed method effectively alleviates the difficulty of comprehensive distribution similarity evaluation and achieves a more objective similarity evaluation of position and density indicators. Finally, the established similarity evaluation system is applied to real tunnel construction in Hebei Province, China, providing application value for the accuracy of fracture modeling in practical engineering. Highlights: A comprehensive method for evaluating similarity between 2D fracture maps is proposed Five indicators are suggested, including spacing, length, angle, position, and density. Grouping characteristics of trace lines are considered in similarity calculation. Proposed method achieves a more objective evaluation of position and density indicators. [ABSTRACT FROM AUTHOR]

Is ethics about anything? Cora Diamond has famously argued that ethics lacks a subject matter by providing a variety of examples of ethical discourse, which, she claims, are ethically significant without being about anything ethical. They do not have a moral subject matter, but are nonetheless instances of moral thinking. This raises the question what it means for a piece of discourse to be moral. What does Diamond mean by the concept of ethics? Diamond never gives this question a direct answer, which is a cause for concern, among other things because there is reason to worry that any workable account of the concept of ethics will lead back to the idea that ethics has a subject matter. I explain how this worry can be averted by construing the concept of ethics as a family resemblance concept. [ABSTRACT FROM AUTHOR]

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Haploid males of hymenopteran species produce gametes through an abortive meiosis I followed by meiosis II that can either be symmetric or asymmetric in different species. Thus, one spermatocyte could give rise to two spermatids with either equal or unequal amounts of cytoplasm. It is currently unknown what molecular features accompany these postmeiotic sperm cells especially in species with asymmetric meiosis II such as bees. Here we present testis single-cell RNA sequencing datasets from the honeybee (Apis mellifera) drones of 3 and 14 days after emergence (3d and 14d). We show that, while 3d testes exhibit active, ongoing spermatogenesis, 14d testes only have late-stage spermatids. We identify a postmeiotic bifurcation in the transcriptional roadmap during spermatogenesis, with cells progressing toward the annotated spermatids (SPT) and small spermatids (sSPT), respectively. Despite an overall similarity in their transcriptomic profiles, sSPTs express the fewest genes and the least RNA content among all the sperm cell types. Intriguingly, sSPTs exhibit a relatively high expression level for Hymenoptera-restricted genes and a high mutation load, suggesting that the special meiosis II during spermatogenesis in the honeybee is accompanied by phylogenetically young gene activities. Author summary: Previous histological studies suggest that spermatogenesis is concluded before adult emergence in the honeybee. We complement this histological atlas on testis development and spermatogenesis with a comprehensive dataset from the honeybee adult testes, including single-cell RNA, long-read RNA, bulk mRNA and DNA-seq data. Through the use of gene orthology between the honeybee (Apis mellifera) and Drosophila melanogaster, we show that in newly emerged drones, spermatogenesis is an ongoing process and meiosis II results in two separable clusters of spermatid cells. One of them is identified to contain small spermatids, which are consistent with previous anatomical detection of polar body-like cells in close association with regular spermatids. The characteristic features of small spermatids include an overall low transcription level, high expression of evolutionarily young genes, an enrichment of gene activities regulated by ETS-domain transcription factors, and a high level of mutation load. This work establishes the foundation for future investigations into molecular mechanisms of sperm quality assurance in the honeybee. [ABSTRACT FROM AUTHOR]

Objectives Two new classifications of myeloid neoplasms have recently been published: the International Consensus Classification (ICC) and the 5th edition of the World Health Organization classification (WHO5). We sought to examine the real-world impact of dueling classifications on patient diagnoses. Methods Our institutional pathology database was searched, and 237 specimens with a diagnosis of myeloid neoplasia were randomly selected. For each case, a classification based on the WHO5 and the ICC was assigned. The WHO5 and ICC diagnoses were compared to determine their degree of concordance. Results After applying the WHO5 and ICC diagnostic criteria, 134 (56.5%) cases were classified as concordant, 63 (26.6%) cases had terminological differences, 37 (15.6%) cases had minor diagnostic discrepancies, and 3 (1.3%) cases had major diagnostic discrepancies. Cases with minor diagnostic discrepancies included 25 cases of myelodysplastic syndrome (MDS), 10 cases of acute myeloid leukemia (AML), and 2 cases of myeloid precursor lesions. Cases with major diagnostic discrepancies included 2 cases that were diagnosed as MDS, not otherwise specified (NOS), according to the ICC but classified as AML with NPM1 alteration and AML with RBM15::MRTFA according to the WHO5 and 1 case that was characterized as chronic myelomonocytic leukemia according to the ICC and as AML with NPM1 alteration according to the WHO5. Conclusions This study confirms that a majority of cases are classified similarly using the 2 systems. Given the overall similarity of the systems, future harmonization of the classifications should be pursued to avoid confusion and multiple diagnoses. [ABSTRACT FROM AUTHOR]

Semantic and soritical paradoxes display remarkable family resemblances. For one thing, several non-classical logics have been independently applied to both kinds of paradoxes. For another, revenge paradoxes and higher-order vagueness—among the most serious problems targeting solutions to semantic and soritical paradoxes—exhibit a rather similar dynamics. Some authors have taken these facts to suggest that truth and vagueness require a unified logical framework, or perhaps that the truth predicate is itself vague. However, a common core of semantic and soritical paradoxes has not been identified yet, and no explanation of their relationships has been provided. Here we aim at filling this lacuna, in the framework of many-valued logics. We provide a unified diagnosis of semantic and soritical paradoxes, identifying their source in a general form of indiscernibility. We then develop our diagnosis into a theory of paradoxicality, which formalizes both semantic and soritical paradoxes as arguments involving specific instances of our generalized indiscernibility principle, and correctly predicts which logics can non-trivially solve them. [ABSTRACT FROM AUTHOR]

This article combines two things: it explores how one should undertake the project of defining 'fundamentalism' and, based on the ensuing desiderata, it actually provides such a definition. After a few preliminary comments on 'fundamentalism' and the value of defining it, five goals of definitions are distinguished and elucidated: accuracy, precision, fairness, clarity, and fecundity. After that, various kinds of definitions and their interrelations are spelled out. Finally, the author provides and defends a so-called explicative definition of 'fundamentalism' both in terms of necessary and sufficient conditions and in terms of stereotypical properties. On the basis of empirical literature and a scoping review, it is argued that a movement is fundamentalist if and only if it is (i) reactionary towards modern developments, (ii) itself modern, and (iii) based on a grand historical narrative. More specifically, a movement is fundamentalist if it exemplifies a large number of the following properties: (i) it is reactionary in its rejection of liberal ethics, science, or technological exploitation; (ii) it is modern in seeking certainty and control, embracing literalism and infallibility about particular scriptures, actively using media and technology, or making universal claims; and (iii) it presents a grand historical narrative in terms of paradise, fall, and redemption, or cosmic dualism. [ABSTRACT FROM AUTHOR]

This paper will address ethical concerns surrounding the representation of vulnerable groups as well as the methodological challenges inherent in using artificial intelligence and human-like computer-generated characters in human studies that involve representing such groups. Such concerns focus on consequences arising from the technological affordances of new systems for creating narratives, as well as graphical and audio representations that are capable of portraying beings with close resemblance to humans. Enacting such virtual representations of humans inevitably gives rise to important ethical questions: (1) Who has the right to tell certain stories? (2) Is it ethical to change the medium of a narrative and the identity of a protagonist? (3) Do such changes, or technological mediations, affect whether a vulnerable group will be fairly and accurately portrayed? (4) And what are the implications, either way? While the backdrop of the paper involves discussing the potential of virtual representation as a meditative tool for moral and social change, the ethical implications inherent in the use of new cutting-edge technologies, such as OpenAI's ChatGPT and Unreal Engine's MetaHuman, to create human-like virtual character narratives call for theoretical scrutiny from a methodological perspective. [ABSTRACT FROM AUTHOR]

Thousand-grain weight is the main parameter for accurately estimating rice yields, and it is an important indicator for variety breeding and cultivation management. The accurate detection and counting of rice grains is an important prerequisite for thousand-grain weight measurements. However, because rice grains are small targets with high overall similarity and different degrees of adhesion, there are still considerable challenges preventing the accurate detection and counting of rice grains during thousand-grain weight measurements. A deep learning model based on a transformer encoder and coordinate attention module was, therefore, designed for detecting and counting rice grains, and named TCLE-YOLO in which YOLOv5 was used as the backbone network. Specifically, to improve the feature representation of the model for small target regions, a coordinate attention (CA) module was introduced into the backbone module of YOLOv5. In addition, another detection head for small targets was designed based on a low-level, high-resolution feature map, and the transformer encoder was applied to the neck module to expand the receptive field of the network and enhance the extraction of key feature of detected targets. This enabled our additional detection head to be more sensitive to rice grains, especially heavily adhesive grains. Finally, EIoU loss was used to further improve accuracy. The experimental results show that, when applied to the self-built rice grain dataset, the precision, recall, and mAP@0.5 of the TCLE–YOLO model were 99.20%, 99.10%, and 99.20%, respectively. Compared with several state-of-the-art models, the proposed TCLE–YOLO model achieves better detection performance. In summary, the rice grain detection method built in this study is suitable for rice grain recognition and counting, and it can provide guidance for accurate thousand-grain weight measurements and the effective evaluation of rice breeding. [ABSTRACT FROM AUTHOR]

Legionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH, 253 kDa in size with no sequence similarity to proteins of known function is toxic when overexpressed in host cells. SidH is regulated by the LP metaeffector LubX which targets SidH for degradation in a temporal manner during LP infection. The mechanism underlying the toxicity of SidH and its role in LP infection are unknown. Here, we determined the cryo-EM structure of SidH at 2.7 Å revealing a unique alpha helical arrangement with no overall similarity to known protein structures. Surprisingly, purified SidH came bound to a E. coli EF-Tu/t-RNA/GTP ternary complex which could be modeled into the cryo-EM density. Mutation of residues disrupting the SidH-tRNA interface and SidH-EF-Tu interface abolish the toxicity of overexpressed SidH in human cells, a phenotype confirmed in infection of Acanthamoeba castellani. We also present the cryo-EM structure of SidH in complex with a U-box domain containing ubiquitin ligase LubX delineating the mechanism of regulation of SidH. Our data provide the basis for the toxicity of SidH and into its regulation by the metaeffector LubX. Legionella pneumophila secretes hundreds of effectors to facilitate infection. Here, Sharma et al show that the virulence effector SidH adopts a unique α-helical conformation, leading to toxicity via tRNA binding site and resolve the structural basis of SidH regulation through ubiquitination. [ABSTRACT FROM AUTHOR]

Digital companions are an advanced form of digital agents that do not only provide advice and support but accompany people on their day‐to‐day customer journeys. This article sheds light on the psychological processes underlying customers' responses to these digital companions (i.e., virtual friends or co‐consumers). We propose that framing them as matched with customers on goal‐relevant attributes (i.e., attributes related to customers' consumption goals) fosters positive customer outcomes (i.e., consumption enjoyment and positive word‐of‐mouth), mediated by perceived similarity in these attributes. Importantly, in this matching context, humanlikeness serves as a boundary condition for perceived similarity to occur. Furthermore, the effect of perceived similarity on customer outcomes is driven by perceived connectedness. In Study 1, in the context of experiential learning, we identified shared interest and personality as goal‐relevant attributes underlying perceived similarity. With the manipulation of the match frame and humanlike versus artificial voice of the digital companion, Study 2 supports our propositions and highlights shared interest, but not personality, as the core driver. We provide recommendations on how to design and market digital companions to foster connection and favorable customer outcomes. [ABSTRACT FROM AUTHOR]

We can see personhood as a philosophical and historical struggle between positive and negative forms of 'being at one', a struggle most succinctly described by Hölderlin, a central figure in Romanticism and in German idealism through his close friendship and collaboration with Schelling and Hegel. For Hölderlin, 'Being at one is god-like and good, but human, too human, the mania / Which insists there is only the One, one country, one truth and one way'. This paper is an exploration of a range of forms of aloneness, linked by the family resemblance of a number of such 'solitude' terms (loneliness, solitude, solitary, aloneness, lonesome, individual, atonement) to the idea of 'oneness'. 'Being at one' was distinctively articulated in the Romantic period, in philosophy as well as in the arts. Based on this distinctiveness, this article presents an historical account of the developing philosophical anthropology of being at one, dividing the development of 'being at one' between the pre-Romantic, Romantic, and post-Romantic eras. [ABSTRACT FROM AUTHOR]

Variations with respect to perspective, lighting, weather, and interference from dynamic objects may all have an impact on the accuracy of the entire system during autonomous positioning and during the navigation of mobile visual simultaneous localization and mapping (SLAM) robots. As it is an essential element of visual SLAM systems, loop closure detection plays a vital role in eradicating front-end-induced accumulated errors and guaranteeing the map's general consistency. Presently, deep-learning-based loop closure detection techniques place more emphasis on enhancing the robustness of image descriptors while neglecting similarity calculations or the connections within the internal regions of the image. In response to this issue, this article proposes a loop closure detection method based on similarity differences between image blocks. Firstly, image descriptors are extracted using a lightweight convolutional neural network (CNN) model with effective loop closure detection. Subsequently, the image pairs with the greatest degree of similarity are evenly divided into blocks, and the level of similarity among the blocks is used to recalculate the degree of the overall similarity of the image pairs. The block similarity calculation module can effectively reduce the similarity of incorrect loop closure image pairs, which makes it easier to identify the correct loopback. Finally, the approach proposed in this article is compared with loop closure detection methods based on four distinct CNN models with a recall rate of 100% accuracy; said approach performs significantly superiorly. The application of the block similarity calculation module proposed in this article to the aforementioned four CNN models can increase the recall rate's accuracy to 100%; this proves that the proposed method can successfully improve the loop closure detection effect, and the similarity calculation module in the algorithm has a certain degree of universality. [ABSTRACT FROM AUTHOR]

Wireless communication smart bracelet data include motion data, sleep time data, heart rate and blood pressure data and positioning data, etc. These data have diversity and high complexity, and there are interconnections or interactions between the data, which have high clustering difficulty. To this end, a new data clustering algorithm is studied for wireless communication smart bracelets. The K-medoids algorithm is used to calculate the intra-cluster, inter-cluster, or overall similarity to complete the initial clustering of the bracelet data. Setting the clustering evaluation index can determine the optimal number of clusters. The data objects that are closely surrounded and relatively dispersed are selected as the initial clustering centers and combined with the new index IXB to complete the improvement of the data clustering algorithm. The test results show that the accuracy, recall, and F1 of the research algorithm for clustering the heart rate monitoring dataset, temperature monitoring dataset, energy consumption dataset, and sleep monitoring dataset are higher than 97%, which indicates that the data clustering effect of the algorithm is good. [ABSTRACT FROM AUTHOR]

In this paper I propose and motivate a logic of the interdefined concepts of making true and control, understood as intensional propositional operators to be indexed to an agent. While bearing a resemblance to earlier logics in the tradition, the motivations, semantics, and object language theory differ on crucial points. Applying this logic to widespread formal theories of agency, I use it as a framework to argue against the ubiquitous assumption that the strongest actions or options available to a given agent must always be pairwise incompatible. The conclusion is that this assumption conflicts with failures of higher order control of agents over their degree or precision of control, failures exhibited by such imperfect agents as ourselves. I discuss models in this setting for understanding such imperfectly self-controlling agents. In an appendix, I prove several relevant results about the logic described, including soundness and completeness both for it and for certain natural extensions. [ABSTRACT FROM AUTHOR]

Logical form and logical analysis as the search for it have been introduced during the development of logic and analytical philosophy and are still widely considered as key tools or methods for the solution of philosophical puzzles. It is instructive to have a look at a criticism of these presupositions and I present Wittgenstein as the author who provides such a criticism. I present a development of his view of logical form which went from the thesis of the ineffability of logical form to the denial of the meaningfulness of the notion of logical form as such. This refusal is linked to Wittgenstein’s abandonment of the idea of the language of pure experience. The method of philosophical therapies is presented as an alternative to logical analysis and this methodology is linked with Wittgenstein’s consideration of game and family resemblance. [ABSTRACT FROM AUTHOR]

Some North American indigenous languages have names for 'common nighthawk' (Chordeiles minor)', 'robin', and 'bird' that are strikingly similar phonetically and have served to advocate long-distance genetic relationships among language families. While the Algonquian proto-form for 'nighthawk' has a rather straightforward pedigree, this is not the case for Siouan languages. Despite their phonetic resemblance, the ornithonyms for 'nighthawk' in half a dozen Siouan languages are unrelated; some are mimetic innovations and others are borrowed. This article analyses how and why ornithonyms are problematic in the application of the comparative method, a reality that affects the validity of long-distance claims, and offers alternative ways to deal with this issue. While ornithonyms can be inherited and undergo all the regular sound changes (or not) like other words, they are also problematic in many respects. First, they can be onomatopoetic and imitate the cry or call of the bird in question – a feature that accounts for their cross-linguistic similarity. Second, they can undergo ad hoc mimetic reshaping or become lexically contaminated based on phonetic similarity with other ornithonyms or words with which they are associated culturally. Third and last, they can be borrowed internally or externally. However, despite these comparative pitfalls (i.e., that some phonetically similar forms in a language family are not cognates), the analysis shows that our understanding of ornithological nomenclature can be enhanced by considering elements of ornithology, mythology, ethnographic knowledge, sayings, and puns pertaining to birds. [ABSTRACT FROM AUTHOR]

This work explores the determinants of decisions by former apprentices to present product offerings similar to those of their masters. Using a quantitative study of 194 international chefs, this article argues that there is a negative association between the degree to which a master rebels against the rules and conventions of a field and master-apprentice similarity. It also shows that master status and a creative professional's career stage during an apprenticeship moderate the association between master rebellion and master-apprentice similarity. The work concludes by outlining some implications for the career development and creativity of creative professionals and the emergence of new styles. [ABSTRACT FROM AUTHOR]

Negative spillovers due to firms' product-harm crises have attracted the attention of marketing researchers owing to the devastating and irrecoverable damage they can cause. Despite the extensive research undertaken on this topic, studies concerning spillovers across competing brands from different companies are relatively scant. Drawing upon self-construal theory, we propose that spillover effects across competing brands from different companies may vary depending on consumers' self-construal and on the perceived similarity between the brands. The results of two studies show that, when the brands' perceived similarity is high, the spillover effect of a product-harm crisis on a competing brand from a different company is greater for consumers with interdependent self-construal than for those with independent self-construal. Our findings extend the theoretical knowledge of spillover effects and provide meaningful managerial implications for global corporations. [ABSTRACT FROM AUTHOR]