1. Impact of Indoor Radon Exposure on Lung Cancer Incidence in Slovenia.
- Author
-
Birk, Mojca, Žagar, Tina, Tomšič, Sonja, Lokar, Katarina, Mihor, Ana, Bric, Nika, Mlakar, Miran, and Zadnik, Vesna
- Subjects
- *
RISK assessment , *STATISTICAL models , *STATISTICAL correlation , *RESEARCH funding , *RADIOACTIVE pollution of the atmosphere , *LUNG tumors , *RESEARCH methodology , *RESEARCH , *INDOOR air pollution , *RADON , *EPIDEMIOLOGICAL research , *DISEASE risk factors - Abstract
Simple Summary: Lung cancer is one of the most frequently diagnosed cancers worldwide. Radon is a radioactive gas whose concentrations can accumulate indoors. The long-term exposure to radon is considered carcinogenic to humans and is an important risk factor for lung cancer. Our epidemiological study investigated the impact of indoor radon exposure on the incidence of lung cancer in Slovenia over a period of 40 years. Around 60 newly diagnosed cases of lung cancer per year (out of a population of around 2 million) can be attributed to radon exposure in residential environments in the period 1978–2017, which corresponds to 5.5% of all lung cancer cases. The most important information that needs to be communicated to the Slovenian public and decision-makers about the health risk and about support for preventive measures is that living in areas with elevated radon levels is associated with a higher risk of lung cancer. Indoor radon is an important risk factor for lung cancer, as 3–14% of lung cancer cases can be attributed to radon. The aim of our study was to estimate the impact of indoor radon exposure on lung cancer incidence over the last 40 years in Slovenia. We analyzed the distribution of lung cancer incidence across 212 municipalities and 6032 settlements in Slovenia. The standardized incidence ratios were smoothed with the Besag–York–Mollie model and fitted with the integrated nested Laplace approximation. A categorical explanatory variable, the risk of indoor radon exposure with low, moderate and high risk values, was added to the models. We also calculated the population attributable fraction. Between 2.8% and 6.5% of the lung cancer cases in Slovenia were attributable to indoor radon exposure, with values varying by time period. The relative risk of developing lung cancer was significantly higher among the residents of areas with a moderate and high risk of radon exposure. Indoor radon exposure is an important risk factor for lung cancer in Slovenia in areas with high natural radon radiation (especially in the southern and south-eastern parts of the country). [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF