21 results on '"Colozza N"'
Search Results
2. Nuovi elettrodi stampati paper-based per il monitoraggio dei processi degradativi del cemento armato
- Author
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Arduini, F, Colozza, N, Sassolini, A, Mazzaracchio, V, Luca, F, Kersti, H, and MOSCONE DINIA, D
- Subjects
Settore CHIM/01 - Published
- 2019
3. Monitoraggio della corrosione nelle barre di rinforzo per le strutture in cemento armato
- Author
-
Arduini, F, Colozza, N, Sassolini, A, Abruzzese, D, Micheletti, A, and Tiero, A
- Subjects
corrosione ,cemento armato ,barre di armatura ,sensori elettrochimici ,Settore CHIM/01 ,Settore ICAR/08 - Published
- 2019
4. Electroanalysis moves towards paper-based printed electronics
- Author
-
Cinti, S., Colozza, N., Cacciotti, I., Moscone, D., Polomoshnov, M., Sowade, E., Baumann, R.R., Arduini, F., and Publica
- Abstract
Herein we demonstrated, for the first time, the possibility to use the paper employed in printed electronics (i.e. p_e:smart) as substrate to develop a paper-based sensor. To improve the electrochemical performances of the inkjet-printed sensor, a dispersion based on carbon black nanoparticles was used to modify the working electrode, allowing for a highly performant nanomodified electrochemical sensor platform. This disposable sensor was characterized both electrochemically and morphologically, and it has been successively challenged towards a model analyte namely ascorbic acid. It has been evidenced that the presence of carbon black as nanomodifier decreased the overpotential for ascorbic acid oxidation (from 0.47 V to 0.28 V) with respect to the unmodified sensor and boosted the sensitivity (ca. 3-times). The applicability of this printed electrochemical sensor was demonstrated for the detection of ascorbic acid in a dietary supplement, quantifying 999 ± 130 mg with respect to the 1000 mg reported on the label.
- Published
- 2018
5. Electroanalytical Sensor Based on Gold-Nanoparticle-Decorated Paper for Sensitive Detection of Copper Ions in Sweat and Serum
- Author
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Simona Roggero, Neda Bagheri, Paolo A. Netti, Vincenzo Mazzaracchio, Stefano Cinti, Danila Moscone, Noemi Colozza, Mohammad Saraji, Fabiana Arduini, Concetta Di Natale, Bagheri, N., Mazzaracchio, V., Cinti, S., Colozza, N., Di Natale, C., Netti, P. A., Saraji, M., Roggero, S., Moscone, D., and Arduini, F.
- Subjects
Analyte ,Microfluidics ,Metal Nanoparticles ,Nanoparticle ,chemistry.chemical_element ,Nanotechnology ,Biosensing Techniques ,Standard solution ,010402 general chemistry ,01 natural sciences ,Analytical Chemistry ,law.invention ,Biosensing Technique ,law ,Ion ,Sweat ,Ions ,Filter paper ,010401 analytical chemistry ,Copper ,0104 chemical sciences ,chemistry ,Reagent ,Gold ,Atomic absorption spectroscopy - Abstract
The growth of (bio)sensors in analytical chemistry is mainly attributable to the development of affordable, effective, portable, and user-friendly analytical tools. In the field of sensors, paper-based devices are gaining a relevant position for their outstanding features including foldability, ease of use, and instrument-free microfluidics. Herein, a multifarious use of filter paper to detect copper ions in bodily fluids is reported by exploiting this eco-friendly material to (i) synthesize AuNPs without the use of reductants and/or external stimuli, (ii) print the electrodes, (iii) load the reagents for the assay, (iv) filter the gross impurities, and (v) preconcentrate the target analyte. Copper ions were detected down to 3 ppb with a linearity up to 400 ppb in standard solutions. The applicability in biological matrices, namely, sweat and serum, was demonstrated by recovery studies and by analyzing these biofluids with the paper-based platform and the reference method (atomic absorption spectroscopy), demonstrating satisfactory accuracy of the novel eco-designed analytical tool.
- Published
- 2021
6. A challenge in biosensors: Is it better to measure a photon or an electron for ultrasensitive detection?
- Author
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Patrizia Simoni, Martina Zangheri, Elisa Marchegiani, Laura Fabiani, Aldo Roda, Noemi Colozza, Danila Moscone, Mara Mirasoli, Fabiana Arduini, Roda A., Arduini F., Mirasoli M., Zangheri M., Fabiani L., Colozza N., Marchegiani E., Simoni P., and Moscone D.
- Subjects
Chemiluminescence ,Biomedical Engineering ,Biophysics ,Amperometry ,Reproducibility of Result ,Nanotechnology ,Electrons ,02 engineering and technology ,Biosensing Techniques ,Immunosensor ,Electron ,01 natural sciences ,Horseradish peroxidase ,Sensitivity and Specificity ,law.invention ,Biosensing Technique ,Settore CHIM/01 ,law ,Electrochemistry ,Electrochemical biosensor ,Enzyme-based biosensor ,Photons ,Electrochemical Technique ,biology ,Chemistry ,Paper-based assay ,010401 analytical chemistry ,Reproducibility of Results ,General Medicine ,Electrochemical Techniques ,021001 nanoscience & nanotechnology ,Photon ,0104 chemical sciences ,Luminescent Measurement ,Luminescent Measurements ,biology.protein ,0210 nano-technology ,Biosensor ,Biotechnology - Abstract
Biosensor development exploiting various transduction principles is characterized by a strong competition to reach high detectability, portability and robustness. Nevertheless, a literature-based comparison is not possible, as different conditions are employed in each paper. Herein, we aim at evaluating which measurement, photons or electrons, yields better biosensor performance. Upon outlining an update in recent achievements to boost analytical performance, amperometry and chemiluminescence (CL)-based biosensors are directly compared employing the same biospecific reagents and analytical formats. Horseradish peroxidase (HRP) and hydrogen peroxide concentrations were directly measured, while glucose and mouse IgG were detected employing an enzyme paper-based biosensor and an immunosensor, respectively. Detectability was down to picomoles of hydrogen peroxide (4 pmol for CL and 210 pmol for amperometry) and zeptomoles of HRP (45 zmol for CL and 20 zmol for amperometry); IgG was detected down to 12 fM (CL) and 120 fM (amperometry), while glucose down to 17 μM (CL) and 40 μM (amperometry). Results showed that amperometric and CL biosensors offered similar detectability and analytical performance, with some peculiarities that suggest complementary application fields. As they generally provided slightly higher detectability and wider dynamic ranges, CL-based biosensors appear more suitable for point-of-care testing of clinical biomarkers, where detectability is crucial. Nevertheless, as high detectability in CL biosensors usually requires longer acquisition times, their rapidity will allocate electrochemical biosensors in real-time monitoring and wearable biosensors. The analytical challenge demonstrated that these biosensors have competitive and similar performance, and between photons and electrons the competition is still open.
- Published
- 2019
7. Electroanalysis moves towards paper-based printed electronics: carbon black nanomodified inkjet-printed sensor for ascorbic acid detection as a case study
- Author
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Reinhard R. Baumann, Enrico Sowade, Danila Moscone, Fabiana Arduini, Ilaria Cacciotti, Stefano Cinti, Maxim Polomoshnov, Noemi Colozza, Cinti, S., Colozza, N., Cacciotti, I., Moscone, D., Polomoshnov, M., Sowade, E., Baumann, R. R., and Arduini, F.
- Subjects
Analyte ,Materials science ,Working electrode ,Nanotechnology ,02 engineering and technology ,Substrate (printing) ,Overpotential ,01 natural sciences ,Paper-based sensor ,Electroanalysi ,Carbon black ,Materials Chemistry ,Ascorbic acidCarbon blackElectroanalysisInkjet printingPaper-based sensorsPrinted electronics ,Settore CHIM/01 - Chimica Analitica ,Electrical and Electronic Engineering ,Instrumentation ,010401 analytical chemistry ,Metals and Alloys ,Printed electronics ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Ascorbic acid ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Electrochemical gas sensor ,Inkjet printing ,0210 nano-technology - Abstract
Herein we demonstrated, for the first time, the possibility to use the paper employed in printed electronics (i.e. p_e:smart) as substrate to develop a paper-based sensor. To improve the electrochemical performances of the inkjet-printed sensor, a dispersion based on carbon black nanoparticles was used to modify the working electrode, allowing for a highly performant nanomodified electrochemical sensor platform. This disposable sensor was characterized both electrochemically and morphologically, and it has been successively challenged towards a model analyte namely ascorbic acid. It has been evidenced that the presence of carbon black as nanomodifier decreased the overpotential for ascorbic acid oxidation (from 0.47 V to 0.28 V) with respect to the unmodified sensor and boosted the sensitivity (ca. 3-times). The applicability of this printed electrochemical sensor was demonstrated for the detection of ascorbic acid in a dietary supplement, quantifying 999 ± 130 mg with respect to the 1000 mg reported on the label.
- Published
- 2018
8. Paper-Based Electrochemical (Bio)Sensors for the Detection of Target Analytes in Liquid, Aerosol, and Solid Samples.
- Author
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Colozza N, Mazzaracchio V, and Arduini F
- Abstract
The last decade has been incredibly fruitful in proving the multifunctionality of paper for delivering innovative electrochemical (bio)sensors. The paper material exhibits unprecedented versatility to deal with complex liquid matrices and facilitate analytical detection in aerosol and solid phases. Such remarkable capabilities are feasible by exploiting the intrinsic features of paper, including porosity, capillary forces, and its easy modification, which allow for the fine designing of a paper device. In this review, we shed light on the most relevant paper-based electrochemical (bio)sensors published in the literature so far to identify the smart functional roles that paper can play to bridge the gap between academic research and real-world applications in the biomedical, environmental, agrifood, and security fields. Our analysis aims to highlight how paper's multifarious properties can be artfully harnessed for breaking the boundaries of the most classical applications of electrochemical (bio)sensors.
- Published
- 2024
- Full Text
- View/download PDF
9. Paper as smart support for bioreceptor immobilization in electrochemical paper-based devices.
- Author
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Seddaoui N, Colozza N, Gullo L, and Arduini F
- Subjects
- Molecularly Imprinted Polymers, Antibodies, Engineering, Electrochemical Techniques, Biosensing Techniques
- Abstract
The use of paper as a smart support in the field of electrochemical sensors has been largely improved over the last 15 years, driven by its outstanding features such as foldability and porosity, which enable the design of reagent and equipment-free multi-analysis devices. Furthermore, the easy surface engineering of paper has been used to immobilize different bioreceptors, through physical adsorption, covalent bonding, and electrochemical polymerization, boosting the fine customization of the analytical performances of paper-based biosensors. In this review, we focused on the strategies to engineer the surface of the paper for the immobilization of (bio)recognition elements (eg., enzymes, antibodies, DNA, molecularly imprinted polymers) with the overriding goal to develop accurate and reliable paper-based electrochemical biosensors. Furthermore, we highlighted how to take advantage of paper for designing smart configurations by integrating different analytical processes in an eco-designed analytical tool, starting from the immobilization of the (bio)receptor and the reagents, through a designed sample flow along the device, until the analyte detection., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
10. Nanomaterials and paper-based electrochemical devices: merging strategies for fostering sustainable detection of biomarkers.
- Author
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Caratelli V, Di Meo E, Colozza N, Fabiani L, Fiore L, Moscone D, and Arduini F
- Subjects
- Reproducibility of Results, Biomarkers, Cellulose, Nanostructures chemistry, Biosensing Techniques
- Abstract
In the last few decades, nanomaterials have made great advances in the biosensor field, thanks to their ability to enhance several key issues of biosensing analytical tools, namely, sensitivity, selectivity, robustness, and reproducibility. The recent trend of sustainability has boosted the progress of novel and eco-designed electrochemical paper-based devices to detect easily the target analyte(s) with high sensitivity in complex matrices. The huge attention given by the scientific community and industrial sectors to paper-based devices is ascribed to the numerous advantages of these cost-effective analytical tools, including the absence of external equipment for solution flow, thanks to the capillary force of paper, the fabrication of reagent-free devices, because of the loading of reagents on the paper, and the easy multistep analyses by using the origami approach. Besides these features, herein we highlight the multifarious aspects of the nanomaterials such as (i) the significant enlargement of the electroactive surface area as well as the area available for the desired chemical interactions, (ii) the capability of anchoring biorecognition elements on the electrode surface on the paper matrix, (iii) the improvement of the conductivity of the cellulose matrix, (iv) the functionality of photoelectrochemical properties within the cellulose matrix, and (v) the improvement of electrochemical capabilities of conductive inks commonly used for electrode printing on the paper support, for the development of a new generation of paper-based electrochemical biosensors applied in the biomedical field. The state of the art over the last ten years has been analyzed highlighting the various functionalities that arise from the integration of nanomaterials with paper-based electrochemical biosensors for the detection of biomarkers.
- Published
- 2022
- Full Text
- View/download PDF
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