721 results on '"errors-in-variables"'
Search Results
402. Smoothing Splines Estimators in Functional Linear Regression with Errors-in-Variables
- Author
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Kneip, Alois, Crambes, Christophe, Cardot, Herve, and Sarda, Pascal
- Subjects
Errors-in-Variables ,Functional Linear Model ,ddc:330 ,Smoothing Splines ,Total Least Squares ,Penalization - Abstract
This work deals with a generalization of the Total Least Squares method in the context of the functional linear model. We first propose a smoothing splines estimator of the functional coefficient of the model without noise in the covariates and we obtain an asymptotic result for this estimator. Then, we adapt this estimator to the case where the covariates are noisy and we also derive an upper bound for the convergence speed. Our estimation procedure is evaluated by means of simulations.
- Published
- 2006
403. Errors-in-variables based identification of autoregressive parameters for speech enhancement using one microphone
- Author
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Bobillet, William, Grivel, Eric, Najim, Mohamed, Diversi, Roberto, Guidorzi, Roberto, Soverini, Umberto, W. Bobillet, E. Grivel, M. Najim, R. Diversi, R. Guidorzi, U. Soverini, and Grivel, Eric
- Subjects
Errors-in-Variables ,Kalman ,SPEECH ENHANCEMENT ,[INFO.INFO-TS] Computer Science [cs]/Signal and Image Processing ,Computer Science::Sound ,ERRORS-IN-VARIABLES MODELS ,OPTIMAL SMOOTHING ,NOISY AUTOREGRESSIVE MODELS ,[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processing - Abstract
Parametric approaches based on a priori models of the speech are often used in the framework of speech enhancement using a single microphone. When the speech is modeled by means of a stationary autoregressive (AR) process, a frame-by-frame approach is usually considered. However, it requires the unbiased estimations of the autoregressive parameters and of the noise variances for the subsequent implementation of a filter (Kalman, H-infinity, etc.). The purpose of this paper is twofold. Firstly, we propose to view the AR parameter estimation as an errors-in-variables issue. Secondly, we implement an optimal smoothing procedure based on a constrained minimum variance estimation of the signal. Then, we test the procedure based on both steps in the field of speech enhancement.
- Published
- 2006
404. Estimation of nonlinear models with Berkson measurement errors
- Author
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Liqun Wang
- Subjects
65C05 ,Statistics and Probability ,simulation-based estimator ,asymptotic normality ,Asymptotic distribution ,Mathematics - Statistics Theory ,Statistics Theory (math.ST) ,01 natural sciences ,semiparametric model ,010104 statistics & probability ,62J02, 62F12 (Primary) 65C60, 65C05 (Secondary) ,Consistency (statistics) ,0502 economics and business ,FOS: Mathematics ,Nonlinear regression ,Applied mathematics ,62J02 ,0101 mathematics ,050205 econometrics ,Mathematics ,Parametric statistics ,method of moments ,consistency ,05 social sciences ,Mathematical statistics ,Nonparametric statistics ,Estimator ,Regression analysis ,65C60 ,weighted least squares ,errors-in-variables ,Statistics, Probability and Uncertainty ,62F12 ,minimum distance estimator - Abstract
This paper is concerned with general nonlinear regression models where the predictor variables are subject to Berkson-type measurement errors. The measurement errors are assumed to have a general parametric distribution, which is not necessarily normal. In addition, the distribution of the random error in the regression equation is nonparametric. A minimum distance estimator is proposed, which is based on the first two conditional moments of the response variable given the observed predictor variables. To overcome the possible computational difficulty of minimizing an objective function which involves multiple integrals, a simulation-based estimator is constructed. Consistency and asymptotic normality for both estimators are derived under fairly general regularity conditions., Published at http://dx.doi.org/10.1214/009053604000000670 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
- Published
- 2005
405. Nonparametric Estimation of the Regression Function in an Errors-in-Variables Model
- Author
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Comte , Fabienne, Taupin , Marie-Luce, Mathématiques Appliquées Paris 5 (MAP5 - UMR 8145), Université Paris Descartes - Paris 5 (UPD5)-Institut National des Sciences Mathématiques et de leurs Interactions (INSMI)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Mathématiques d'Orsay (LM-Orsay), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Mathématiques Appliquées à Paris 5 ( MAP5 - UMR 8145 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National des Sciences Mathématiques et de leurs Interactions-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Mathématiques d'Orsay ( LM-Orsay ), and Université Paris-Sud - Paris 11 ( UP11 ) -Centre National de la Recherche Scientifique ( CNRS )
- Subjects
Projection estimators ,Mathematics - Statistics Theory ,Nonparametric regression ,[STAT.TH]Statistics [stat]/Statistics Theory [stat.TH] ,Statistics Theory (math.ST) ,[ STAT.TH ] Statistics [stat]/Statistics Theory [stat.TH] ,Errors-in-variables ,Density deconvolution ,(Secondary) 62G05, 62G20 ,MSC 2000 Primary 62G08, 62G07. Secondary 62G05, 62G20 ,Adaptive estimation ,[MATH.MATH-ST]Mathematics [math]/Statistics [math.ST] ,FOS: Mathematics ,Minimax estimation ,(Primary) 62G08, 62G07 ,[ MATH.MATH-ST ] Mathematics [math]/Statistics [math.ST] - Abstract
We consider the regression model with errors-in-variables where we observe $n$ i.i.d. copies of $(Y,Z)$ satisfying $Y=f(X)+\xi, \; Z=X+\sigma\varepsilon$, involving independent and unobserved random variables $X,\xi,\varepsilon$. The density $g$ of $X$ is unknown, whereas the density of $\sigma\varepsilon$ is completely known. Using the observations $(Y_i, Z_i)$, $i=1,\cdots,n$, we propose an estimator of the regression function $f$, built as the ratio of two penalized minimum contrast estimators of $\ell=fg$ and $g$, without any prior knowledge on their smoothness. We prove that its $\mathbb{L}_2$-risk on a compact set is bounded by the sum of the two $\mathbb{L}_2(\mathbb{R})$-risks of the estimators of $\ell$ and $g$, and give the rate of convergence of such estimators for various smoothness classes for $\ell$ and $g$, when the errors $\varepsilon$ are either ordinary smooth or super smooth. The resulting rate is optimal in a minimax sense in all cases where lower bounds are available.
- Published
- 2005
- Full Text
- View/download PDF
406. Modeling and Control of Bilinear Systems : Application to the Activated Sludge Process
- Author
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Ekman, Mats
- Subjects
Automatic control ,optimal control ,Reglerteknik ,activated sludge process ,bilinear systems ,modeling ,errors-in-variables ,Control Engineering ,parameter estimation - Abstract
This thesis concerns modeling and control of bilinear systems (BLS). BLS are linear but not jointly linear in state and control. In the first part of the thesis, a background to BLS and their applications to modeling and control is given. The second part, and likewise the principal theme of this thesis, is dedicated to theoretical aspects of identification, modeling and control of mainly BLS, but also linear systems. In the last part of the thesis, applications of bilinear and linear modeling and control to the activated sludge process (ASP) are given.
- Published
- 2005
407. Application of structured total least squares for system identification and model reduction
- Author
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Rik Pintelon, Jan C. Willems, Ivan Markovsky, Bart De Moor, S. Van Huffel, Ljung, L., Electricity, and Vrije Universiteit Brussel
- Subjects
Mathematical optimization ,DAISY ,Linear system ,System identification ,Errors-in-variables ,Computer Science Applications ,Parameter identification problem ,LTI system theory ,MPUM ,Control and Systems Engineering ,Norm (mathematics) ,model reduction ,Errors-in-variables models ,numerical software ,structured total least squares ,Electrical and Electronic Engineering ,Total least squares ,Latent variable model ,Mathematics - Abstract
The following identification problem is considered: Minimize the /spl lscr//sub 2/ norm of the difference between a given time series and an approximating one under the constraint that the approximating time series is a trajectory of a linear time invariant system of a fixed complexity. The complexity is measured by the input dimension and the maximum lag. The question leads to a problem that is known as the global total least squares problem and alternatively can be viewed as maximum likelihood identification in the errors-in-variables setup. Multiple time series and latent variables can be considered in the same setting. Special cases of the problem are autonomous system identification, approximate realization, and finite time optimal /spl lscr//sub 2/ model reduction. The identification problem is related to the structured total least squares problem. This paper presents an efficient software package that implements the theory. The proposed method and software are tested on data sets from the database for the identification of systems DAISY.
- Published
- 2005
408. Analysis of Some Methods for Identifying Dynamic Errors-in-variables Systems
- Author
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Hong, Mei and Hong, Mei
- Abstract
A system where errors or noises are present on both the inputs and the outputs is called an errors-in-variables (EIV) system. EIV systems appear in industrial and agricultural processes, medical sciences, economical systems, biotechnology, as well as in many other areas. Until now, a considerable number of methods for identifying dynamic errors-in-variables systems have been proposed. This thesis studies the statistic properties of different EIV methods and explores the relationships between some of the existing methods. An EIV approach, based on a bias-compensated least squares scheme, is considered in this thesis. Three promising estimators are in focus, namely, Zheng's bias-eliminated least squares (BELS) methods, Frisch scheme methods and extended compensated least squares (ECLS) methods. A simplified form of the BELS equation is first proposed. The new equation will simplify the computation and the theoretical analysis. Next, an important relationship between the BELS, Frisch and ECLS methods is found. The defining non-linear equations used by these three methods are equivalent, providing that the same extended model is used. This means that despite the use of different techniques to solve these equations, the three methods will have the same asymptotic estimation accuracy. Furthermore, the thesis studies the convergence properties of BELS. An alternative BELS algorithm is proposed, which has less of a divergence problem under low SNR situations as compared to the classic BELS methods. Another important problem which is investigated in the thesis is the asymptotic accuracy of the estimates. For the BELS method and a third-order cumulants based method, explicit expressions for the covariance matrices of the parameter estimates are derived. With such expressions available, one may obtain insight into how different user choices in the algorithms influence the accuracy. By using the expressions for the covariance matrices, comparisons of the estimation accuracies a
- Published
- 2008
409. SIMEX and TLS: An equivalence result
- Author
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Polzehl, Jörg and Zwanzig, Silvelyn
- Subjects
SIMEX ,62J05 ,Moment estimator ,Total Least Squares ,62F12 ,Errors-in-variables - Abstract
SIMEX was introduced by Cook and Stefanski (1994) as a simulation type estimator in errors-in-variables models. The idea of the SIMEX procedure is to compensate for the effect of the measurement errors while still using naive regression estimators. Polzehl and Zwanzig (2004) defined a symmetrized version of this estimator. In this paper we establish some results relating these two simulation-extrapolation-type estimators to well known consistent estimators like the total least squares estimator (TLS) and the moment estimator (MME) in the context of errors-in-variables models. We further introduce an adaptive SIMEX (ASIMEX), which is calculated like SIMEX, but based on an estimated variance. The main result of this paper is that SYMEX, ASIMEX are equivalent to TLS. Additionally we see that SIMEX is equivalent to the moment estimator.
- Published
- 2004
- Full Text
- View/download PDF
410. Robust Estimators of Errors-in-Variables Models: Part 1
- Author
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Quirino Paris
- Subjects
Ratio of error variances ,Mean squared error ,Research Methods/ Statistical Methods ,Monte Carlo experiments ,Estimator ,Joint least squares ,Least trimmed squares ,Robust Estimators ,Control variates ,Newey–West estimator ,Robust regression ,Minimum-variance unbiased estimator ,Statistics ,Errors-in-variables models ,errors-in-variables ,concentrated joint least squares ,Mathematics - Abstract
It is well known that consistent estimators of errors-in-variables models require knowledge of the ratio of error variances. What is not well known is that a Joint Least Squares estimator is robust to a wide misspecification of that ratio. Through a series of Monte Carlo experiments we show that an easy-to-implement estimator produces estimates that are nearly unbiased for a wide range of the ratio of error variances. These MC analyses encompass linear and nonlinear specifications and also a system on nonlinear equations where all the variables are measured with errors.
- Published
- 2004
- Full Text
- View/download PDF
411. Errors in Trade Classification: Consequences and Remedies
- Author
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Carsten Tanggaard
- Subjects
Adverse selection ,classification error ,effective spread ,errors-in-variables ,International trade ,Foreign trade ,Nomenclature GMM ,measurement errors ,realized spread ,TORQ ,trade indicator - Abstract
The consequences of errors in trade classification are potentially worse than documented in existing empirical research. This is demonstrated by the use of a formal model of classification errors in a generic regression-type microstructure model. The bias is a function of the probability of trade-reversal in addition to the probability of an error. These parameters depend on stock and trade characteristics in addition to trading procedures and trade reporting standards. The bias is highly sensitive to the background variables, thus causing concern about the validity of empirical studies applying possibly erroneous classification methods without controlling for such effects. The theory, outlined in the paper, predicts that given empirical evidence on error rates, effective spreads must realistically be expected to be downward biased by more than 50%. However, the bias one can observe from using the TORQ database is less severe and has the opposite sign. This is due to special features of the NYSE trading process which may not carry over to other markets. This research also emphasizes the need for proper adjustment of classification error bias. Therefore, the paper proposes a GMM estimator for improved estimation. Simulation evidence indicates that in medium and larger sized samples the method is capable of removing virtually all the bias in market quality statistics like e¤ective, realized, and adverse selection spreads. This is empirically verified in an application to data from TORQ.
- Published
- 2003
412. Spatial Statistics in the Presence of Location Error with an Application to Remote Sensing of the Environment
- Author
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Noel A Cressie and John Kornak
- Subjects
geographic information systems ,Statistics and Probability ,Geographic information system ,business.industry ,GPS ,General Mathematics ,Spatial database ,Total Ozone Mapping Spectrometer ,Geostatistics ,GIS ,Attribute error ,Kriging ,FP model ,Environmental science ,Errors-in-variables models ,geostatistics ,kriging ,Satellite ,errors-in-variables ,Statistics, Probability and Uncertainty ,business ,Spatial analysis ,CP model ,Remote sensing - Abstract
Techniques for the analysis of spatial data have, to date, tended to ignore any effect caused by error in specifying the spatial locations at which measurements are recorded. This paper reviews the methods for adjusting spatial inference in the presence of data-location error, particularly for data that have a continuous spatial index (geostatistical data). New kriging equations are developed and evaluated based on a simulation experiment. They are also applied to remote-sensing data from the Total Ozone Mapping Spectrometer instrument on the Nimbus-7 satellite, where the location error is caused by assignment of the data to their nearest grid-cell centers. The remote-sensing data measure total column ozone (TCO), which is important for protecting the Earth's surface from ultraviolet and other radiation.
- Published
- 2003
- Full Text
- View/download PDF
413. Estimation in Binary Choice Models with Measurement Errors
- Author
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Edgerton, David and Jochumzen, Peter
- Subjects
jel:C29 ,Statistics::Methodology ,jel:C25 ,Measurement error ,errors-in-variables ,probit ,binary choice ,bounds - Abstract
In this paper we develop a simple maximum likelihood estimator for probit models where the regressors have measurement error. We first assume precise information about the reliability ratios (or, equivalently, the proxy correlations) of the regressors. We then show how reasonable bounds for the parameter estimates can be obtained when only imprecise information is available. The analysis is also extended to situations where the measurement error has non-zero mean and is correlated with the true values of the regressors. An extensive simulation study shows that the estimator works very well, even in quite small samples. Finally the method is applied to data explaining sick leave in Sweden.
- Published
- 2003
414. Quantile Regression Estimates for a Class of Linear and Partially Linear Errors-in-Variables Models
- Author
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He, Xuming, Liang, Hua, He, Xuming, and Liang, Hua
- Abstract
We consider the problem of estimating quantile regression coefficients in errors-in-variables models. When the error variables for both the response and the manifest variables have a joint distribution that is spherically symmetric but otherwise unknown, the regression quantile estimates based on orthogonal residuals are shown to be consistent and asymptotically normal. We also extend the work to partially linear models when the response is related to some additional covariate.
- Published
- 2006
415. Robust Estimators of Errors-In-Variables Models Part 1
- Author
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Paris, Quirino, Paris, Quirino, Paris, Quirino, and Paris, Quirino
- Abstract
It is well known that consistent estimators of errors-in-variables models require knowledge of the ratio of error variances. What is not well known is that a Joint Least Squares estimator is robust to a wide misspecification of that ratio. Through a series of Monte Carlo experiments we show that an easy-to-implement estimator produces estimates that are nearly unbiased for a wide range of the ratio of error variances. These MC analyses encompass linear and nonlinear specifications and also a system on nonlinear equations where all the variables are measured with errors.
- Published
- 2004
416. Practical bandwidth selection in deconvolution kernel density estimation
- Author
-
UCL - EUEN/STAT - Institut de statistique, Delaigle, Aurore, Gijbels, Irène, UCL - EUEN/STAT - Institut de statistique, Delaigle, Aurore, and Gijbels, Irène
- Abstract
Kernel estimation of a density based on contaminated data is considered and the important issue of how to choose the bandwidth parameter in practice is discussed. Some plug-in (PI) type of bandwidth selectors, which are based on non-parametric estimation of an approximation of the mean integrated squared error, are proposed. The selectors are a refinement of the simple normal reference bandwidth selector, which is obtained by parametrically estimating the approximated mean integrated squared error by referring to a normal density. A simulation study compares these PI bandwidth selectors with a bootstrap (BT) and a cross-validated (CV) bandwidth selector. It is concluded that in finite samples, an appropriately chosen PI bandwidth selector and the BT bandwidth selector perform comparably and both outperform the CV bandwidth. The use of the various practical bandwidth selectors is illustrated on a real data example. (C) 2002 Elsevier B.V. All rights reserved.
- Published
- 2004
417. Estimation in Binary Choice Models with Measurement Errors
- Author
-
Jochumzen, Peter and Jochumzen, Peter
- Abstract
In this paper we develop a simple maximum likelihood estimator for probit models where the regressors have measurement error. We first assume precise information about the reliability ratios (or, equivalently, the proxy correlations) of the regressors. We then show how reasonable bounds for the parameter estimates can be obtained when only imprecise information is available. The analysis is also extended to situations where the measurement error has non-zero mean and is correlated with the true values of the regressors. An extensive simulation study shows that the estimator works very well, even in quite small samples. Finally the method is applied to data explaining sick leave in Sweden
- Published
- 2003
418. New Tools for Dealing with Errors-in-Variables in DEA
- Author
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Laurens Cherchye, Timo Kuosmanen, and Thierry Post
- Subjects
Data Envelopment Analysis (DEA) ,errors-in-variables ,efficiency depth ,robust reference sets ,financial institutions - Abstract
The axiomatic literature on technical efficiency measurement has drawn attention to the indication problem of the Debreu-Farrell (DF) measure. We follow a shadow price approach to preserve the DF benchmark while reconciling it with the Koopmans efficiency characterization. First, we define a set of Koopmans efficient references that can be rationalized in a similar way as the DF projection. The indication problem is then captured using a measure of implicit allocative or mix efficiency, also interpretable as a dominance measure in price space. We consequently present a mix-adjusted DF framework for efficiency measurement in which e.g. the Zieschang (1984) procedure can be
- Published
- 2000
419. Estimation in a semiparametric partially linear errors-in-variables model
- Author
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Wolfgang Karl Härdle, Raymond J. Carroll, and Hua Liang
- Subjects
Statistics and Probability ,partially linear model ,Errors-in-variables ,structural relations ,Law of large numbers ,60F05 ,Statistics ,Applied mathematics ,62H25 ,Semiparametric regression ,62E25 ,Mathematics ,Observational error ,Linear model ,Estimator ,Semiparametric model ,orthogonal regression ,Standard error ,Errors-in-variables models ,semiparametric models ,nonparametric likelihood ,62H12 ,Statistics, Probability and Uncertainty ,62J99 ,62F12 ,measurement error ,62F10 - Abstract
We consider the partially linear model relating a response $Y$ to predictors ($X, T$) with mean function $X^{\top}\beta + g(T)$ when the $X$’s are measured with additive error. The semiparametric likelihood estimate of Severini and Staniswalis leads to biased estimates of both the parameter $\beta$ and the function $g(\cdot)$ when measurement error is ignored. We derive a simple modification of their estimator which is a semiparametric version of the usual parametric correction for attenuation. The resulting estimator of $\beta$ is shown to be consistent and its asymptotic distribution theory is derived. Consistent standard error estimates using sandwich-type ideas are also developed.
- Published
- 1999
420. Stochastic Frontier Production Function With Errors-In-Variables
- Author
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Dhawan, Rajeev and Jochumzen, Peter
- Subjects
Errors-In-Variables ,Stochastic Frontier ,Technical Efficiency ,Reliability Ratio ,jel:C21 ,jel:D24 ,jel:C15 - Abstract
This paper develops a procedure for estimating parameters of a cross-sectional stochastic frontier production function when the factors of production suffer from measurement errors. Specifically, we use Fuller's (1987) reliability ratio concept to develop an estimator for the model in Aigner et al (1977). Our Monte-Carlo simulation exercise illustrates the direction and the severity of bias in the estimates of the elasticity parameters and the returns to scale feature of the production function when using the traditional maximum-likelihood estimator (MLE) in presence of measurement errors. In contrast the reliability ratio based estimator consistently estimates these parameters even under extreme degree of measurement errors. Additionally, estimates of firm level technical efficiency are severely biased for traditional MLE compared to reliability ratio estimator, rendering inter-firm efficiency comparisons infeasible. The seriousness of measurement errors in a practical setting is demonstrated by using data for a cross-section of publicly traded U.S. corporations.
- Published
- 1999
421. Nutrient Demand Elasticities with Noisy Measures of Household Resources
- Author
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Gibson, John
- Subjects
Consumer/Household Economics ,Demand and Price Analysis ,Income ,Errors-in-variables ,Food Consumption/Nutrition/Food Safety ,Nutrition - Abstract
Many studies suggest that changes in household economic resources (incomes and expenditure) have little effect on nutrient intakes and child malnutrition in developing countries. This paper examines the impact that errors-in-variables have on inferences about the importance of household incomes to the calorie and protein demands of households. Results are based on a new household survey from Papua New Guinea, with repeated observations on households during the year. These repeated observations allow regression estimates to be corrected for the differing reliabilities of the explanatory variables.
- Published
- 1999
- Full Text
- View/download PDF
422. Asymptotic properties of an estimator in errors-in-variables models in the presence of validation data
- Author
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Sándor Baran, Jørgen Lauridsen, and István Fazekas
- Subjects
Asymptotic distribution ,Estimator ,Asymptotic theory (statistics) ,Consistency of estimators ,Errors-in-variables ,Domain (mathematical analysis) ,Regression ,Measurement errors ,Computational Mathematics ,Computational Theory and Mathematics ,Természettudományok ,Consistency (statistics) ,Modelling and Simulation ,Modeling and Simulation ,Validation ,Statistics ,Applied mathematics ,Errors-in-variables models ,Random fields ,Matematika- és számítástudományok ,Mixing property ,Mathematics - Abstract
Structural errors-in-variables models with dependent spatial observations are studied. The presence of validation data is assumed. An estimator for regression parameters proposed by Lee and Sepanski [1] is studied. Consistency and asymptotic normality of the estimator are established in the case of increasing domain. Infill asymptotic properties are described. Simulation results are also presented.
- Published
- 1999
423. EM Algorithm for Electricity Pool Price Prediction and Errors-in-variables Process Identification
- Author
-
Wu, Ouyang
- Subjects
- EM algorithm, Errors-in-variables, Pool price prediction, Multiple model
- Abstract
Abstract: In this thesis, under the EM algorithm framework, a multiple model approach is developed towards electricity price prediction, and the identification problem for errors-in-variables (EIV) systems is studied. Alberta's electricity price, which shows high volatility and erratic nature, is considered as an example of a nonlinear process. A Markov regime-switching model is applied to predict the price using the local models through the investigations of characteristics of the pool price sequence. The expectation maximization (EM) algorithm is applied to solve the maximum likelihood (ML) estimation problem for model parameters, and several initialization methods are proposed to generate the initial values for the EM algorithm. The validations are presented to verify the proposed approach, which demonstrate an improvement on the existing price prediction for the range of high electricity prices. A dynamic system that has both input and output measurement errors is considered as an errors-in-variables (EIV) system. Employment of traditional identification strategies for EIV systems will result in biased estimates and inaccurate estimation of system parameters. EIV approaches such as the subspace EIV method has been proposed, but the subspace approach does not possess the optimality such as ML estimation. However, the direct application of ML approach for EIV model parameter estimation can lead to intractable solutions. In this work, we assume a dynamic model for noise-free input and propose to solve the ML problem using the EM algorithm. To identify industrial nonlinear EIV processes that operate along an operating trajectory, a linear parameter varying (LPV) EIV model is proposed to approximate the global models. The EM algorithm is used to solve the ML estimation for LPV EIV model parameters. Various numerical simulations and pilot-scale experiments are used to demonstrate the effectiveness of the proposed approach.
- Published
- 2016
424. Estimation in a semiparametric partially linear errors-in-variables model
- Author
-
Liang, Hua, Härdle, Wolfgang, Carroll, Raymond J., Liang, Hua, Härdle, Wolfgang, and Carroll, Raymond J.
- Abstract
We consider the partially linear model relating a response $Y$ to predictors ($X, T$) with mean function $X^{\top}\beta + g(T)$ when the $X$’s are measured with additive error. The semiparametric likelihood estimate of Severini and Staniswalis leads to biased estimates of both the parameter $\beta$ and the function $g(\cdot)$ when measurement error is ignored. We derive a simple modification of their estimator which is a semiparametric version of the usual parametric correction for attenuation. The resulting estimator of $\beta$ is shown to be consistent and its asymptotic distribution theory is derived. Consistent standard error estimates using sandwich-type ideas are also developed.
- Published
- 1999
- Full Text
- View/download PDF
425. Time-Domain Identification of Dynamic Errors-in-Variables Systems using Period Excitation Signals
- Author
-
Forssell, Urban, Gustafsson, Fredrik, McKelvey, Tomas, Forssell, Urban, Gustafsson, Fredrik, and McKelvey, Tomas
- Abstract
The use of periodic excitation signals in identification experiments is advocated. With periodic excitation it is possible to separate the driving signals and the disturbances, which for instance implies that the noise properties can be independently estimated. In the paper a non-parametric noise model, estimated directly from the measured data, is used in a compensation strategy applicable to both least squares and total least squares estimation. The resulting least squares and total least squares methods are applicable in the errors-in-variables situation and give consistent estimates regardless of the noise. The feasibility of the idea is illustrated in a simulation study.
- Published
- 1999
426. Time-Domain Identification of Dynamic Errors-in-Variables Systems Using Periodic Excitation Signals
- Author
-
Forssell, Urban, Gustafsson, Fredrik, and McKelvey, Tomas
- Subjects
Least squares estimation ,Automatic control ,Reglerteknik ,Cybernetik och informationsteori ,System identification ,Errors-in-variables - Abstract
The use of periodic excitation signals in identification experiments is advocated. With periodic excitation it is possible to separate the driving signals and the disturbances, which for instance implies that the noise properties can be independently estimated. In the paper a non-parametric noise model, estimated directly from the measured data, is used in a compensation strategy applicable to both least squares and total least squares estimation. The resulting least squares and total least squares methods are applicable in the errors-in-variables situation and give consistent estimates regardless of the noise. The feasibility of the idea is illustrated in a simulation study.
- Published
- 1998
427. Existence results for special nonlinear total least squares problem
- Author
-
Rudolf Scitovski and Dragan Jukić
- Subjects
Applied Mathematics ,Mathematical analysis ,Explained sum of squares ,Least trimmed squares ,Generalized least squares ,Least squares ,Iteratively reweighted least squares ,Non-linear least squares ,total least squares ,orthogonal least squares ,errors-in-variables ,generalized logistic function ,parameter estimation ,Applied mathematics ,Lack-of-fit sum of squares ,Total least squares ,Analysis ,Mathematics - Abstract
In this paper we prove an existence theorem for a special nonlinear total least squares problem. We show that the optimal parameters of the generalized logistic function exist in the sense of total least squares, provided the data satisfy the Chebyshev's inequality.
- Published
- 1998
428. Large Sample Theory in a Semiparametric Partially Linear Errors-in-Variables Models
- Author
-
Liang, Hua, Härdle, Wolfgang, and Carroll, Raymond J.
- Subjects
Errors-in-Variables ,Functional Relations ,Partially Linear Model ,Semiparametric Models ,330 Wirtschaft ,ddc:330 ,17 Wirtschaft ,Measurement Error ,Non-parametric Likelihood ,Orthogonal Regression ,Structural Relations - Published
- 1997
429. Panel Data with Errors-in-Variables: A Note on Essential and Redundant Orthogonality Conditions in GMM-estimation
- Author
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Erik Biørn and Tor Jakob Klette
- Subjects
Panel Data ,Errors-in-Variables ,Instrumental Variables ,GMM Estimation ,Generalized inverse ,jel:C23 ,jel:C12 ,jel:C13 ,jel:C33 - Abstract
General Method of Moments (GMM) estimation of a linear one-equation model using panel data with errors-in-variables is considered. To eliminate fixed individual heterogeneity, the equation is differenced across one or more than one periods and estimated by means of instrumental variables. With non-autocorrelated measurement error, we show that only the one-period and a few two-period differences are essential, i.e. relevant for GMM-estimation. GMM estimation based on all orthogonality conditions on the basis of a generalized inverse formulation is shown to be equivalent to estimation using only the essential orthogonality conditions
- Published
- 1997
430. Design Aspects of Calibration Studies in Nutrition, with Analysis of Missing Data in Linear Measurement Error Models
- Author
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Carroll, Raymond J., Freedman, Laurence, and Pee, David
- Subjects
Maximum Likelihood ,330 Wirtschaft ,17 Wirtschaft ,Sampling Designs ,Weighting ,Estimating Equations ,Semiparametrics ,Model Robustness ,Errors-in-Variables ,Missing Data ,ddc:330 ,Linear regression ,Stratified Sampling ,Measurement Error ,Nutrition ,Method of Moments - Abstract
Motivated by an example in nutritional epidemiology, we investigate some design and analysis aspects of linear measurement error models with missing surrogate data. The specific problem investigated consists of an initial large sample in which the response (a food frequency questionnaire, FFQ) is observed, and then a smaller calibration study in which replicates of the error prone predictor are observed (food records or recalls, FR). The difference between our analysis and most of the measurement error model literature is that in our study, the selection into the calibration study can depend upon the value of the response. Rationale for this type of design is given. Two major problems are investigated. In the design of a calibration study, one has the option of larger sample sizes and fewer replicates, or smaller sample sizes and more replicates. Somewhat surprisingly, neither strategy is uniformly preferable in cases of practical interest. The answers depend on the instrument used (recalls or records) and the parameters of interest. The second problem investigated is one of analysis. In the usual linear model with no missing data, method of moments estimates and normal-theory maximum likelihood estimates are approximately equivalent, with the former method in most use because it can be calculated easily and explicitly. Both estimates are valid without any distributional assumptions. In contrast, in the missing data problem under consideration, only the moments estimate is distribution-free, but the maximum likelihood estimate has at least 50% greater precision in practical situations when normality obtains. Implications for the design of nutritional calibration studies are discussed.
- Published
- 1997
431. Panel data with errors-in-variables : a note on essential and redundant orthogonality conditions in GMM-estimation
- Author
-
Biørn, Erik and Klette, Tor Jakob
- Subjects
JEL classification: C13 ,Statistical methods ,JEL classification: C12 ,Statistics models ,jel:C23 ,Instrumental variables ,Errors-in-variables ,Errors-in-Variables ,ddc:330 ,C13 ,GMM Estimation ,C33 ,C12 ,Panel data ,JEL classification: C23 ,jel:C12 ,jel:C13 ,jel:C33 ,Panel Data ,General Method of Moments (GMM) ,Computer Science::Sound ,Instrumental Variables ,Mathematics and natural science: 400::Mathematics: 410::Statistics: 412 [VDP] ,Generalized inverse ,JEL classification: C33 ,Estimation ,C23 - Abstract
General Method of Moments (GMM) estimation of a linear one-equation model using panel data with errors-in-variables is considered. To eliminate fixed individual heterogeneity, the equation is differenced across one or more than one periods and estimated by means of instrumental variables. With non-autocorrelated measurement error, we show that only the one-period and a few two-period differences are essential, i.e. relevant for GMM-estimation. GMM estimation based on all orthogonality conditions on the basis of a generalized inverse formulation is shown to be equivalent to estimation using only the essential orthogonality conditions Keywords: Panel Data, Errors-in-Variables, Instrumental Variables, GMM Estimation, Generalized inverse
- Published
- 1997
432. Quantile regression estimates for a class of linear and partially linear errors-in-variables models
- Author
-
He, Xuming and Liang, Hua
- Subjects
semiparametric model ,Statistics::Theory ,Kernel ,regression quantile ,ddc:330 ,linear regression ,Statistics::Methodology ,errors-in-variables ,Statistics::Computation - Abstract
We consider the problem of estimating quantile regression coefficients in errors-in-variables models. When the error variables for both the response and the manifest variables have a joint distribution that is spherically symmetric but otherwise unknown, the regression quantile estimates based on orthogonal residuals are shown to be consistent and asymptotically normal. We also extend the work to partially linear models when the response is related to some additional covariate.
- Published
- 1997
433. Asymptotic normality of parametric part in partially linear models with measurement error in the nonparametric part
- Author
-
Liang, Hua
- Subjects
Errors-in-Variables ,Partially Linear Model ,Semiparametric Models ,ddc:330 ,Nonparametric Likelihood ,Measurement Error - Abstract
We consider the partially linear model relating a response Y to predictors (X,T) with mean function XT Ø + g(T) when the T's are measured with additive error. We derive an estimator of Ø by modification local-likelihood method. The resulting estimator of Ø is shown to be asymptotically normal.We consider the partially linear model relating a response Y to predictors (X,T) with mean function XT Ø + g(T) when the T's are measured with additive error. We derive an estimator of Ø by modification local-likelihood method. The resulting estimator of Ø is shown to be asymptotically normal.
- Published
- 1997
434. Transformations of Additivity in Measurement Error Models
- Author
-
Eckert, R. Stephen, Carroll, Raymond J., and Wang, Naisyin
- Subjects
Errors-in-Variables ,Spline Transformations ,SIMEX ,Nonlinear Models ,Regression Calibration ,Transform-Both-Sides ,330 Wirtschaft ,Power Transformations ,ddc:330 ,17 Wirtschaft - Abstract
In many problems one wants to model the relationship between a response Y and a covariate X. Sometimes it is difficult, expensive, or even impossible to observe X directly, but one can instead observe a substitute variable W which is easier to obtain. By far the most common model for the relationship between the actual covariate of interest X and the substitute W is W = X + U, where the variable U represents measurement error. This assumption of additive measurement error may be unreasonable for certain data sets. We propose a new model, namely h(W) = h(X) + U, where h(.) is a monotone transformation function selected from some family H of monotone functions. The idea of the new model is that, in the correct scale, measurement error is additive. We propose two possible transformation families H. One is based of selecting a transformation which makes the within sample mean and standard deviation of replicated W’s uncorrelated. The second is based on selecting the transformation so that the errors (U’s) fit a prespecified distribution. Transformation families used are the parametric power transformations and a cubic spline family. Several data examples are presented to illustrate the methods.
- Published
- 1996
435. Asymptotically honest confidence sets for structural errors-in-variables models
- Author
-
Longcheen Huwang
- Subjects
Statistics and Probability ,converge normally in all parameters ,Coverage probability ,confidence level ,Errors-in-variables ,Confidence interval ,Robust confidence intervals ,asymptotically honest confidence set ,Sample size determination ,Statistics ,Confidence distribution ,High Energy Physics::Experiment ,62F25 ,62J99 ,Statistics, Probability and Uncertainty ,62E99 ,CDF-based nonparametric confidence interval ,Mathematics ,Confidence and prediction bands ,Confidence region - Abstract
The problem of constructing confidence sets for the structural errors-in-variables model is considered under the assumption that the variance of the error associated with the covariate is known. Previously proposed confidence sets for this model suffer from the problem that they all have zero confidence levels for any sample size, where the confidence level of a confidence set is defined to be the infimum of coverage probability over the parameter space. In this paper we construct some asymptotically honest confidence sets; that is, the limiting values of their confidence levels are at least as large as the nominal probabilities when the sample size goes to $\infty$. A desirable property of the proposed confidence set for the slope is also established.
- Published
- 1996
- Full Text
- View/download PDF
436. Total least squares problem for exponential function
- Author
-
Rudolf Scitovski and Dragan Jukić
- Subjects
Characterizations of the exponential function ,Estimation theory ,Applied Mathematics ,Double exponential function ,Computer Science Applications ,Theoretical Computer Science ,Exponential function ,Combinatorics ,Exponential formula ,Exponential growth ,total least squares ,orthogonal least squares ,errors-in-variables ,exponential function ,parameter estimation ,Signal Processing ,Total least squares ,Natural exponential family ,Mathematical Physics ,Mathematics - Abstract
Given the data $(p_i, t_i, f_i), $ $i=1, ldots, m, $ we consider the existence problem for the optimal parameters for the exponential function approximating this data in the sense of total least squares. We give sufficient conditions which guarantee the existence of such optimal parameters.
- Published
- 1996
- Full Text
- View/download PDF
437. Dimension Reduction in a Semiparametric Regression Model with Errors in Covariates
- Author
-
R. K. Knickerbocker, C. Y. Wang, and Raymond J. Carroll
- Subjects
62E20 ,Statistics and Probability ,Statistics::Theory ,Proper linear model ,logistic regression ,Regression analysis ,Nonparametric regression ,Semiparametric model ,62M05 ,kernel regression ,Covariate ,Statistics ,Dimension reduction ,Statistics::Methodology ,Kernel regression ,Principal component regression ,semiparametric models ,errors-in-variables ,Semiparametric regression ,Statistics, Probability and Uncertainty ,Mathematics - Abstract
We consider a semiparametric estimation method for general regression models when some of the predictors are measured with error. The technique relies on a kernel regression of the "true" covariate on all the observed covariates and surrogates. This requires a nonparametric regression in as many dimensions as there are covariates and surrogates. The usual theory copes with such higher-dimensional problems by using higher-order kernels, but this is unrealistic for most problems. We show that the usual theory is essentially as good as one can do with this technique. Instead of regression with higher-order kernels, we propose the use of dimension reduction techniques. We assume that the "true" covariate depends only on a linear combination of the observed covariates and surrogates. If this linear combination were known, we could apply the one-dimensional versions of the semiparametric problem, for which standard kernels are applicable. We show that if one can estimate the linear directions at the root-$n$ rate, then asymptotically the resulting estimator of the parameters in the main regression model behaves as if the linear combination were known. Simulations lend some credence to the asymptotic results.
- Published
- 1995
- Full Text
- View/download PDF
438. Polynomial Regression and Estimation Function in the Presence of Multiplication Measurement Error, with Application to Nutrition
- Author
-
Iturria, Stephen J., Carroll, Raymond J., Firth, David, Iturria, Stephen J., Carroll, Raymond J., and Firth, David
- Abstract
In this paper we consider the polynomial regression model in the presence of multiplicative measurement error in the predictor. Consistent parameter estimates and their associated standard errors are derived. Two general methods are considered, with the methods differing in their assumptions about the distributions of the predictor and the measurement errors. Data from a nutrition study are analyzed using the methods. Finally, the results from a simulation study are presented and the performances of the methods compared.
- Published
- 1997
439. Periodic Excitation for Identification of Dynamic Errors-in-Variables systems Operating in Closed Loop
- Author
-
McKelvey, Tomas and McKelvey, Tomas
- Published
- 1996
440. Errors in Variables and Panel Data: The Labour Demand Response to Permanent Changes in Output
- Author
-
Erik Biørn and Tor Jakob Klette
- Subjects
jel:J23 ,Errors-in-variables ,panel data ,labour demand ,returns to scale ,establishment data ,jel:C23 - Abstract
This paper examines panel data modelling with latent variables in analyzing log-linear relations between inputs and output of firms. Our particular focus is on (i) the "increasing returns to scale puzzle" for labour input and (ii) the GMM estimation in the context of errors-in-variables and panel data. The IV's used for the observed log-differenced output are log output (in level form) for other years than those to which the difference(s) refer. Flexible assumptions are made about the second order moments of the errors, the random coefficients, and other latent variables, allowing, inter alia, for arbitrary heteroskedasticity and autocorrelation up to the first order of the errors-in-variables. We compare OLS, 2SLS, and GMM estimates of the average input response elasticity (which in some cases can be interpreted as an average inverse scale elasticity), and investigate whether year specific estimates differ substantially from those obtained when data for all years are combined. The results confirm the "increasing returns to scale puzzle" for labour input (measured in three different ways), but indicate approximately constant returns to scale when we consider the material input response. This indicates non-homotheticity of the production technology.
- Published
- 1994
441. Correlated Measurement Errors, Bounds on Parameters, and a Model of Producer Behavior
- Author
-
Yngve Willassen and Tor Jakob Klette
- Subjects
Estimation ,errors-in-variables ,parameter bounds ,imperfect competition ,scale economies ,jel:C29 ,jel:C13 ,jel:C43 - Abstract
We examine estimation of a model of producer behavior in the presence of correlated measurement errors in the regressors. Scale economies and price-cost margins are estimated from a set of panel data for manufacturing plants. The paper presents a somewhat new model for estimation of these parameters which is highly flexible but with a simple regression structure. Perhaps the most important contribution of the paper is some new results on deriving parameter bounds for a regression model with errors in variables. In particular, we consider the case where the measurement errors might be correlated. We derive asymptotic standard errors for the parameter bounds. These asymptotic standard errors are compared to bootstrap estimates. Our new results on parameter bounds are applied to the estimation of the model of producer behavior.
- Published
- 1994
442. Errors in Variables and Panel Data: The Labour Demand Response to Permanent Changes in Output
- Author
-
Biørn, Erik and Klette, Tor Jakob
- Subjects
panel data ,EL classification: J23 ,EL classification: C23 ,J23 ,ddc:330 ,labour demand ,establishment data ,returns to scale ,J23 [EL classification] ,Matematikk og Naturvitenskap: 400::Matematikk: 410::Statistikk: 412 [VDP] ,Errors-in-variables ,C23 [EL classification] ,C23 - Abstract
This paper examines panel data modelling with latent variables in analyzing log-linear relations between inputs and output of firms. Our particular focus is on (i) the "increasing returns to scale puzzle" for labour input and (ii) the GMM estimation in the context of errors-in-variables and panel data. The IV's used for the observed log-differenced output are log output (in level form) for other years than those to which the difference(s) refer. Flexible assumptions are made about the second order moments of the errors, the random coefficients, and other latent variables, allowing, inter alia, for arbitrary heteroskedasticity and autocorrelation up to the first order of the errors-in-variables. We compare OLS, 2SLS, and GMM estimates of the average input response elasticity (which in some cases can be interpreted as an average inverse scale elasticity), and investigate whether year specific estimates differ substantially from those obtained when data for all years are combined. The results confirm the 'increasing returns to scale puzzle" for labour input (measured in three different ways), but indicate approximately constant returns to scale when we consider the material input response. This indicates non-homotheticity of the production technology.
- Published
- 1994
443. Correlated Measurement Errors, Bounds on Parameters, and a Model of Producer Behavior
- Author
-
Willassen, Yngve and Klette, Tor Jakob
- Subjects
parameter bounds ,JEL classification: C13 ,C29 ,JEL classification: C29 ,jel:C13 ,jel:C43 ,jel:C29 ,ddc:330 ,C13 ,imperfect competition ,errors-in-variables ,C43 ,Estimation ,JEL classification: C43 ,Matematikk og Naturvitenskap: 400::Matematikk: 410::Statistikk: 412 [VDP] ,scale economies - Abstract
We examine estimation of a model of producer behavior in the presence of correlated measurement errors in the regressors. Scale economies and price-cost margins are estimated from a set of panel data for manufacturing plants. The paper presents a somewhat new model for estimation of these parameters which is highly flexible but with a simple regression structure. Perhaps the most important contribution of the paper is some new results on deriving parameter bounds for a regression model with errors in variables. In particular, we consider the case where the measurement errors might be correlated. We derive asymptotic standard errors for the parameter bounds. These asymptotic standard errors are compared to bootstrap estimates. Our new results on parameter bounds are applied to the estimation of the model of producer behavior. Norges Forskningsrå
- Published
- 1994
444. Bias Robust Estimation in Orthogonal Regression
- Author
-
Ruben H. Zamar
- Subjects
Statistics and Probability ,Polynomial regression ,functional relationship ,Regression dilution ,Omitted-variable bias ,Upper and lower bounds ,Robust regression ,$M$-estimates ,orthogonal regression ,measurement error model ,62J05 ,Statistics ,Outlier ,Applied mathematics ,Errors-in-variables models ,62J02 ,errors-in-variables ,Statistics, Probability and Uncertainty ,Total least squares ,structural relationship ,bias robust ,Mathematics - Abstract
Orthogonal regression $M$-estimates are considered from a bias robust point of view. Their maximum bias over epsilon-contamination neighborhoods is characterized, and maximum bias curves are computed. The most bias robust orthogonal regression $M$-estimate is derived and shown to be a "mode type" estimate; for instance, in the two-dimensional case this estimate can be computed by locating a strip of fixed width covering the maximum number of data points. It will be shown that, although orthogonal regression $M$-estimates with bounded loss function have unbounded influence function, the derivative of their maximum bias curve at zero is finite. Finally, an implicit formula for an upper bound for the breakdown point of all orthogonal regression $M$-estimates is found. The upper bound, which depends on the signal-to-noise ratio, is sharp and attained by the most bias robust estimate.
- Published
- 1992
445. Deconvolution-Based Score Tests in Measurement Error Models
- Author
-
Leonard A. Stefanski and Raymond J. Carroll
- Subjects
Statistics and Probability ,Generalized linear model ,Characteristic function (probability theory) ,score tests ,Nonparametric statistics ,Estimator ,Score ,Deconvolution ,generalized linear models ,Distribution (mathematics) ,62J05 ,density estimation ,Statistics ,Test statistic ,62H25 ,Applied mathematics ,Errors-in-variables models ,62G05 ,errors-in-variables ,measurement error models ,maximum likelihood ,Statistics, Probability and Uncertainty ,empirical Bayes ,Mathematics - Abstract
Consider a generalized linear model with response $Y$ and scalar predictor $X$. Instead of observing $X$, a surrogate $W = X + Z$ is observed, where $Z$ represents measurement error and is independent of $X$ and $Y$. The efficient score test for the absence of association depends on $m(w) = E(X\mid W = w)$ which is generally unknown. Assuming that the distribution of $Z$ is known, asymptotically efficient tests are constructed using nonparametric estimators of $m(w)$. Rates of convergence for the estimator of $m(w)$ are established in the course of proving efficiency of the proposed test.
- Published
- 1991
- Full Text
- View/download PDF
446. Locally Efficient Semiparametric Estimators for Proportional Hazards Models with Measurement Error.
- Author
-
Xu Y, Li Y, and Song X
- Abstract
We propose a new class of semiparametric estimators for proportional hazards models in the presence of measurement error in the covariates, where the baseline hazard function, the hazard function for the censoring time, and the distribution of the true covariates are considered as unknown infinite dimensional parameters. We estimate the model components by solving estimating equations based on the semiparametric efficient scores under a sequence of restricted models where the logarithm of the hazard functions are approximated by reduced rank regression splines. The proposed estimators are locally efficient in the sense that the estimators are semiparametrically efficient if the distribution of the error-prone covariates is specified correctly, and are still consistent and asymptotically normal if the distribution is misspecified. Our simulation studies show that the proposed estimators have smaller biases and variances than competing methods. We further illustrate the new method with a real application in an HIV clinical trial.
- Published
- 2016
- Full Text
- View/download PDF
447. Non-Gaussian Berkson errors in bioassay.
- Author
-
Althubaiti A and Donev A
- Subjects
- Bias, Biostatistics, Computer Simulation, Humans, Models, Statistical, Normal Distribution, Regression Analysis, Research Design statistics & numerical data, Biological Assay statistics & numerical data
- Abstract
The experimental design plays an important role in every experimental study. However, if errors in the settings of the studied factors cannot be avoided, i.e. Berkson errors occur, the estimates of the model parameters may be biased and the variability in the study increased. Correction methods for the effect of Berkson errors are compared. The emphasis is on the study of correlated Berkson errors which follow non-Gaussian distribution as this appears to have been a neglected, yet important, area. It is shown that the regression calibration approach bias correction methods are useful when the Berkson errors are independent. However, when these errors are dependent, the newly proposed method B-SIMEX clearly outperforms the other methods., (© The Author(s) 2012.)
- Published
- 2016
- Full Text
- View/download PDF
448. A Discriminant Function Approach to Adjust for Processing and Measurement Error When a Biomarker is Assayed in Pooled Samples.
- Author
-
Lyles RH, Van Domelen D, Mitchell EM, and Schisterman EF
- Subjects
- Bias, Computer Simulation, Cost-Benefit Analysis, Female, Humans, Meta-Analysis as Topic, Pregnancy, Regression Analysis, Biomarkers, Discriminant Analysis, Likelihood Functions, Odds Ratio, Research Design
- Abstract
Pooling biological specimens prior to performing expensive laboratory assays has been shown to be a cost effective approach for estimating parameters of interest. In addition to requiring specialized statistical techniques, however, the pooling of samples can introduce assay errors due to processing, possibly in addition to measurement error that may be present when the assay is applied to individual samples. Failure to account for these sources of error can result in biased parameter estimates and ultimately faulty inference. Prior research addressing biomarker mean and variance estimation advocates hybrid designs consisting of individual as well as pooled samples to account for measurement and processing (or pooling) error. We consider adapting this approach to the problem of estimating a covariate-adjusted odds ratio (OR) relating a binary outcome to a continuous exposure or biomarker level assessed in pools. In particular, we explore the applicability of a discriminant function-based analysis that assumes normal residual, processing, and measurement errors. A potential advantage of this method is that maximum likelihood estimation of the desired adjusted log OR is straightforward and computationally convenient. Moreover, in the absence of measurement and processing error, the method yields an efficient unbiased estimator for the parameter of interest assuming normal residual errors. We illustrate the approach using real data from an ancillary study of the Collaborative Perinatal Project, and we use simulations to demonstrate the ability of the proposed estimators to alleviate bias due to measurement and processing error.
- Published
- 2015
- Full Text
- View/download PDF
449. Model selection for marginal regression analysis of longitudinal data with missing observations and covariate measurement error.
- Author
-
Shen CW and Chen YH
- Subjects
- Aging, Humans, Longitudinal Studies, Data Interpretation, Statistical, Models, Statistical, Regression Analysis, Research Design
- Abstract
Missing observations and covariate measurement error commonly arise in longitudinal data. However, existing methods for model selection in marginal regression analysis of longitudinal data fail to address the potential bias resulting from these issues. To tackle this problem, we propose a new model selection criterion, the Generalized Longitudinal Information Criterion, which is based on an approximately unbiased estimator for the expected quadratic error of a considered marginal model accounting for both data missingness and covariate measurement error. The simulation results reveal that the proposed method performs quite well in the presence of missing data and covariate measurement error. On the contrary, the naive procedures without taking care of such complexity in data may perform quite poorly. The proposed method is applied to data from the Taiwan Longitudinal Study on Aging to assess the relationship of depression with health and social status in the elderly, accommodating measurement error in the covariate as well as missing observations., (© The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2015
- Full Text
- View/download PDF
450. On the errors-in-variables problem for time series
- Author
-
Peter M. Robinson
- Subjects
Statistics and Probability ,Numerical Analysis ,Observational error ,Series (mathematics) ,seasonality ,Tapering ,Seasonality ,medicine.disease ,Radio spectrum ,trend ,frequency domain regression ,Statistics ,medicine ,tapers ,Errors-in-variables models ,errors-in-variables ,Statistics, Probability and Uncertainty ,Time series ,Approximate solution ,Mathematics - Abstract
The usual assumption in the classical errors-in-variables problem of independent measurement errors cannot necessarily be maintained when the data are time series; errors may be strongly serially correlated, possibly containing seasonal effects and trends. When it is possible to identify frequency bands over which the signal-to-noise ratio is large, an approximate solution to the errors-in-variables problem is to omit the remaining frequencies from a time series regression. We draw attention to the danger of “leakage” from the omitted frequencies, and show that the consequent bias can be reduced by means of tapering.
- Published
- 1986
- Full Text
- View/download PDF
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