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147,650 results on '"coronavirus"'

408. The System of Protection of Social Rights in Ukraine and the EU: European and National Dimension

Author

Olena, Savchuk, Olena, Zinchenko, Hanna, Ponomarova, Viktoriia, Panchenko, Zhanna, Chevychalova, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Nechyporuk, Mykola, editor, Pavlikov, Volodymir, editor, and Krytskyi, Dmytro, editor

Published
2024
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409. Rabbit Viral Diseases (II): Other Viruses

Author

Duarte, Margarida, Fagulha, Teresa, Henriques, Margarida, Barros, Silvia, Ramos, Fernanda, Duarte, Ana, Luís, Tiago, Abade dos Santos, Fábio A., Simões, João, editor, and Monteiro, José M., editor

Published
2024
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410. Impact of COVID-19 on People

Author

Nandal, Neha, Tanwar, Rohit, Saketh, Meduri, Pilania, Urmila, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Marriwala, Nikhil Kumar, editor, Dhingra, Sunil, editor, Jain, Shruti, editor, and Kumar, Dinesh, editor

Published
2024
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413. A Mathematical Study of Reproduction Number and Its Control Strategies in Some Early Epidemic and Corona-Virus Epidemic Model

Author

Sarkar, Abhishek, Agnihotri, Kulbhushan, Das, Krishna Pada, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Singh, Jagdev, editor, Anastassiou, George A., editor, Baleanu, Dumitru, editor, and Kumar, Devendra, editor

Published
2024
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414. Interactive Chatbot for Improving the Text Classification Data Quality

Author

Elzanfaly, Doaa S., Mohamed, Nada Amr, Othman, Nermin Abdelhakim, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Auer, Michael E., editor, and Tsiatsos, Thrasyvoulos, editor

Published
2024
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415. Covid-19 Disease Prediction System from X-Ray Images Using Convolutional Neural Network

Author

Akshitha, Basam, Jagan, A., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Kaiser, M. Shamim, editor, Xie, Juanying, editor, and Rathore, Vijay Singh, editor

Published
2024
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416. Infectious Diseases in Older Persons

Author

Norman, Dean, Yoshikawa, Thomas, Wasserman, Michael R., Section editor, Cesari, Matteo, Section editor, Wasserman, Michael R., editor, Bakerjian, Debra, editor, Linnebur, Sunny, editor, Brangman, Sharon, editor, Cesari, Matteo, editor, and Rosen, Sonja, editor

Published
2024
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417. COVID-19 in Older Adults

Author

Clar, Mia, Walker, Allison, Solomon, Philip, Wasserman, Michael R., Section editor, Cesari, Matteo, Section editor, Wasserman, Michael R., editor, Bakerjian, Debra, editor, Linnebur, Sunny, editor, Brangman, Sharon, editor, Cesari, Matteo, editor, and Rosen, Sonja, editor

Published
2024
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418. Connecting COVID-19 with Autoimmunity

Author

Ghosh, Aritra, Pavlovic, Mirjana D., Larrondo-Petrie, Maria M., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, and Arai, Kohei, editor

Published
2024
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420. Literature Review on Covid-19 Pandemic Emergency Response

Author

Fahmi, Afiqoh Akmalia, Nastiti, Gustisia Rahmi, Setiawan, Eko, Putri, Arinda Soraya, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Mohammed, Bashar S., editor, Min, Teh Hee, editor, Sutanto, Muslich Hartadi, editor, Joewono, Tri Basuki, editor, and As’ad, Sholihin, editor

Published
2024
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421. A Web-Based Vaccine Distribution System for Covid-19 Using Vaxallot

Author

Valarmathi, B., Srinivasa Gupta, N., Prakash, G., BarathyKolappan, A., Padmavathy, N., Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin, Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Pareek, Prakash, editor, Gupta, Nishu, editor, and Reis, M. J. C. S., editor

Published
2024
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422. Analyzing Problems Affecting the Operation of the Construction Enterprise Due to COVID-19 Pandemic—Case Studies in Vietnam

Author

Pham, Vu Hong Son, Bui, Dang Khoa, Tran, Le Anh, Pham, Minh Hoa, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Reddy, J. N., editor, Luong, Van Hai, editor, and Le, Anh Tuan, editor

Published
2024
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424. Anti-Viral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives

Author

Pal, Dilipkumar, Sahu, Pooja, Mérillon, Jean-Michel, Series Editor, Ramawat, Kishan Gopal, Series Editor, Pavlov, Atanas I., Editorial Board Member, Ekiert, Halina Maria, Editorial Board Member, Aggarwal, Bharat B., Editorial Board Member, Jha, Sumita, Editorial Board Member, Wink, Michael, Editorial Board Member, Waffo-Téguo, Pierre, Editorial Board Member, Riviere, Céline, Editorial Board Member, and Pal, Dilipkumar, editor

Published
2024
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426. Infecties van de bovenste luchtwegen

Author

de Jong, M. D., Kroes, A. C. M., Wolfs, T. F. W., Hoepelman, prof. dr. A.I.M., editor, Kroes, prof. dr. A.C.M., editor, Lagrou, prof. dr. K., editor, Van der Hilst, prof. dr. J.C.H., editor, Wertheim, prof. dr. H.F.L., editor, Bonten, prof. dr. M.J.M., editor, van Hellemond, dr. J.J., editor, Vlieghe, prof. dr. E.R.J., editor, and van Vugt, prof. dr. M., editor

Published
2024
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430. Coronavirus Disease 2019 and Airborne Transmission: Science Rejected, Lives Lost. Can Society Do Better?

Author

Morawska, Lidia, Bahnfleth, William, Bluyssen, Philomena M, Boerstra, Atze, Buonanno, Giorgio, Dancer, Stephanie J, Floto, Andres, Franchimon, Francesco, Haworth, Charles, Hogeling, Jaap, Isaxon, Christina, Jimenez, Jose L, Kurnitski, Jarek, Li, Yuguo, Loomans, Marcel, Marks, Guy, Marr, Linsey C, Mazzarella, Livio, Melikov, Arsen Krikor, Miller, Shelly, Milton, Donald K, Nazaroff, William, Nielsen, Peter V, Noakes, Catherine, Peccia, Jordan, Querol, Xavier, Sekhar, Chandra, Seppänen, Olli, Tanabe, Shin-ichi, Tellier, Raymond, Wai, Tham Kwok, Wargocki, Pawel, and Wierzbicka, Aneta

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Prevention, Good Health and Well Being, Humans, COVID-19, SARS-CoV-2, Pandemics, World Health Organization, Societies, airborne transmission, airborne infection spread, coronavirus, SARS-CoV-2 virus, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Abstract

This is an account that should be heard of an important struggle: the struggle of a large group of experts who came together at the beginning of the COVID-19 pandemic to warn the world about the risk of airborne transmission and the consequences of ignoring it. We alerted the World Health Organization about the potential significance of the airborne transmission of SARS-CoV-2 and the urgent need to control it, but our concerns were dismissed. Here we describe how this happened and the consequences. We hope that by reporting this story we can raise awareness of the importance of interdisciplinary collaboration and the need to be open to new evidence, and to prevent it from happening again. Acknowledgement of an issue, and the emergence of new evidence related to it, is the first necessary step towards finding effective mitigation solutions.

Published
2023

431. ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion

Author

Wang, Fulong, Peters, Ryan, Jia, Jingyue, Mudd, Michal, Salemi, Michelle, Allers, Lee, Javed, Ruheena, Duque, Thabata LA, Paddar, Masroor A, Trosdal, Einar S, Phinney, Brett, and Deretic, Vojo

Subjects
Biochemistry and Cell Biology, Biological Sciences, Tuberculosis, Infectious Diseases, Emerging Infectious Diseases, Rare Diseases, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Humans, Animals, Mice, Autophagy-Related Proteins, Autophagy-Related Protein 5, Microtubule-Associated Proteins, Autophagy, ATG5, ESCRT, SARS-CoV-2, atg8ylation, autophagy, coronavirus, exosomes, lysosome, neutrophils, tuberculosis, Medical and Health Sciences, Developmental Biology, Biochemistry and cell biology
Abstract

ATG5 is a part of the E3 ligase directing lipidation of ATG8 proteins, a process central to membrane atg8ylation and canonical autophagy. Loss of Atg5 in myeloid cells causes early mortality in murine models of tuberculosis. This in vivo phenotype is specific to ATG5. Here, we show using human cell lines that absence of ATG5, but not of other ATGs directing canonical autophagy, promotes lysosomal exocytosis and secretion of extracellular vesicles and, in murine Atg5fl/fl LysM-Cre neutrophils, their excessive degranulation. This is due to lysosomal disrepair in ATG5 knockout cells and the sequestration by an alternative conjugation complex, ATG12-ATG3, of ESCRT protein ALIX, which acts in membrane repair and exosome secretion. These findings reveal a previously undescribed function of ATG5 in its host-protective role in murine experimental models of tuberculosis and emphasize the significance of the branching aspects of the atg8ylation conjugation cascade beyond the canonical autophagy.

Published
2023

432. Changes in high-risk sexual behavior, HIV and other STI testing, and PrEP use during the COVID-19 pandemic in a longitudinal cohort of adolescent men who have sex with men 13 to 18 years old in the United States.

Author

Hong, Chenglin, Huh, David, Schnall, Rebecca, Garofalo, Robert, Kuhns, Lisa, Bruce, Josh, Batey, D, Radix, Asa, Belkind, Uri, Hidalgo, Marco, Hirshfield, Sabina, and Pearson, Cynthia

Subjects
HIV prevention, adolescent MSM, condomless anal sex, coronavirus, health disparities, prevalence rates, prospective analysis, Male, Humans, Adolescent, United States, Homosexuality, Male, Pandemics, HIV Infections, Sexual and Gender Minorities, COVID-19, Sexual Behavior, Pre-Exposure Prophylaxis
Abstract

The COVID-19 pandemic has disrupted sexual health services among those most vulnerable to HIV acquisition, such as adolescent men who have sex with men (AMSM). We sought to characterize the changes in sexual-risk behaviors, HIV and other STI testing, and pre-exposure prophylaxis (PrEP) use among a longitudinal cohort of AMSM aged 13 to 18 years before and during the COVID-19 pandemic. We observed a significant decline in HIV testing and a marginal decrease in other STI testing since the pandemic began in March 2020. Outreach efforts and innovative remote delivery of sexual health services are needed to support access to healthcare services among AMSM as the pandemic persists.

Published
2023

433. Vaccination against SARS-CoV-2 using extracellular blebs derived from spike protein-expressing dendritic cells

Author

Chung, Jee Young, Thone, Melissa N, Davies, Jenny E, Gach, Johannes S, Davies, D Huw, Forthal, Donald N, and Kwon, Young Jik

Subjects
Emerging Infectious Diseases, Biodefense, Biotechnology, Vaccine Related, Infectious Diseases, Lung, Prevention, Immunization, 3.4 Vaccines, Prevention of disease and conditions, and promotion of well-being, Infection, Good Health and Well Being, Humans, Antibodies, Neutralizing, Antibodies, Viral, COVID-19, Dendritic Cells, SARS-CoV-2, Spike Glycoprotein, Coronavirus, Vaccination, Controlled antigen presentation, Dendritic cell -derived vesicles, Extracellular blebs, Vaccines, Dendritic cell-derived vesicles, Immunology
Abstract

COVID-19 has caused significant morbidity and mortality worldwide but also accelerated the clinical use of emerging vaccine formulations. To address the current shortcomings in the prevention and treatment of SARS-CoV-2 infection, this study developed a novel vaccine platform that closely mimics dendritic cells (DCs) in antigen presentation and T-cell stimulation in a cell-free and tunable manner. Genetically engineered DCs that express the SARS-CoV-2 spike protein (S) were chemically converted into extracellular blebs (EBs). The resulting EBs elicited potentially protective humoral immunity in vivo, indicated by the production of antibodies that potently neutralized S-pseudotyped virus, presenting EBs as a promising and safe vaccine.

Published
2023

434. Virology under the Microscope-a Call for Rational Discourse.

Author

Goodrum, Felicia, Lowen, Anice C, Lakdawala, Seema, Alwine, James, Casadevall, Arturo, Imperiale, Michael J, Atwood, Walter, Avgousti, Daphne, Baines, Joel, Banfield, Bruce, Banks, Lawrence, Bhaduri-McIntosh, Sumita, Bhattacharya, Deepta, Blanco-Melo, Daniel, Bloom, David, Boon, Adrianus, Boulant, Steeve, Brandt, Curtis, Broadbent, Andrew, Brooke, Christopher, Cameron, Craig, Campos, Samuel, Caposio, Patrizia, Chan, Gary, Cliffe, Anna, Coffin, John, Collins, Kathleen, Damania, Blossom, Daugherty, Matthew, Debbink, Kari, DeCaprio, James, Dermody, Terence, Dikeakos, Jimmy, DiMaio, Daniel, Dinglasan, Rhoel, Duprex, W Paul, Dutch, Rebecca, Elde, Nels, Emerman, Michael, Enquist, Lynn, Fane, Bentley, Fernandez-Sesma, Ana, Flenniken, Michelle, Frappier, Lori, Frieman, Matthew, Frueh, Klaus, Gack, Michaela, Gaglia, Marta, Gallagher, Tom, Galloway, Denise, García-Sastre, Adolfo, Geballe, Adam, Glaunsinger, Britt, Goff, Stephen, Greninger, Alexander, Hancock, Meaghan, Harris, Eva, Heaton, Nicholas, Heise, Mark, Heldwein, Ekaterina, Hogue, Brenda, Horner, Stacy, Hutchinson, Edward, Hyser, Joseph, Jackson, William, Kalejta, Robert, Kamil, Jeremy, Karst, Stephanie, Kirchhoff, Frank, Knipe, David, Kowalik, Timothy, Lagunoff, Michael, Laimins, Laimonis, Langlois, Ryan, Lauring, Adam, Lee, Benhur, Leib, David, Liu, Shan-Lu, Longnecker, Richard, Lopez, Carolina, Luftig, Micah, Lund, Jennifer, Manicassamy, Balaji, McFadden, Grant, McIntosh, Michael, Mehle, Andrew, Miller, W Allen, Mohr, Ian, Moody, Cary, Moorman, Nathaniel, Moscona, Anne, Mounce, Bryan, Munger, Joshua, Münger, Karl, Murphy, Eain, Naghavi, Mojgan, Nelson, Jay, Neufeldt, Christopher, Nikolich, Janko, and O'Connor, Christine

Subjects
COVID-19, Coronavirus, DURC, Gain of function, SARS-CoV-2, biosafety, influenza, pandemic, vaccines, zoonosis, Infectious Diseases, Prevention, Vaccine Related, Immunization, Infection, Good Health and Well Being, Biological Sciences, Medical and Health Sciences, Microbiology
Abstract

Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease burden with vaccines and antivirals. Despite this long history, the COVID-19 pandemic has brought unprecedented attention to the field of virology. Some of this attention is focused on concern about the safe conduct of research with human pathogens. A small but vocal group of individuals has seized upon these concerns - conflating legitimate questions about safely conducting virus-related research with uncertainties over the origins of SARS-CoV-2. The result has fueled public confusion and, in many instances, ill-informed condemnation of virology. With this article, we seek to promote a return to rational discourse. We explain the use of gain-of-function approaches in science, discuss the possible origins of SARS-CoV-2 and outline current regulatory structures that provide oversight for virological research in the United States. By offering our expertise, we - a broad group of working virologists - seek to aid policy makers in navigating these controversial issues. Balanced, evidence-based discourse is essential to addressing public concern while maintaining and expanding much-needed research in virology.

Published
2023

435. One Health Surveillance Highlights Circulation of Viruses with Zoonotic Potential in Bats, Pigs, and Humans in Viet Nam.

Author

Latinne, Alice, Nga, Nguyen Thi Thanh, Long, Nguyen Van, Ngoc, Pham Thi Bich, Thuy, Hoang Bich, Predict Consortium, Long, Pham Thanh, Phuong, Nguyen Thanh, Quang, Le Tin Vinh, Tung, Nguyen, Nam, Vu Sinh, Duoc, Vu Trong, Thinh, Nguyen Duc, Schoepp, Randal, Ricks, Keersten, Inui, Ken, Padungtod, Pawin, Johnson, Christine K, Mazet, Jonna AK, Walzer, Chris, Olson, Sarah H, and Fine, Amanda E

Subjects
Animals, Swine, Chiroptera, Humans, Filoviridae, Coronavirus, Zoonoses, Coronavirus Infections, Phylogeny, Vietnam, One Health, bats, coronavirus, influenza, livestock, paramyxovirus, pigs, spillover, surveillance, zoonoses, Prevention, Vaccine Related, Biodefense, Biotechnology, Emerging Infectious Diseases, Infectious Diseases, 2.2 Factors relating to the physical environment, Aetiology, Infection, Good Health and Well Being, Microbiology
Abstract

A One Health cross-sectoral surveillance approach was implemented to screen biological samples from bats, pigs, and humans at high-risk interfaces for zoonotic viral spillover for five viral families with zoonotic potential in Viet Nam. Over 1600 animal and human samples from bat guano harvesting sites, natural bat roosts, and pig farming operations were tested for coronaviruses (CoVs), paramyxoviruses, influenza viruses, filoviruses and flaviviruses using consensus PCR assays. Human samples were also tested using immunoassays to detect antibodies against eight virus groups. Significant viral diversity, including CoVs closely related to ancestors of pig pathogens, was detected in bats roosting at the human-animal interfaces, illustrating the high risk for CoV spillover from bats to pigs in Viet Nam, where pig density is very high. Season and reproductive period were significantly associated with the detection of bat CoVs, with site-specific effects. Phylogeographic analysis indicated localized viral transmission among pig farms. Our limited human sampling did not detect any known zoonotic bat viruses in human communities living close to the bat cave and harvesting bat guano, but our serological assays showed possible previous exposure to Marburg virus-like (Filoviridae), Crimean-Congo hemorrhagic fever virus-like (Bunyaviridae) viruses and flaviviruses. Targeted and coordinated One Health surveillance helped uncover this viral pathogen emergence hotspot.

Published
2023

437. COVID-19 vaccination-related delayed adverse events among people with rheumatoid arthritis: results from the international COVAD survey

Author

Dey, Mrinalini, Doskaliuk, Bohdana, Parodis, Ioannis, Lindblom, Julius, Wincup, Chris, Joshi, Mrudula, Dey, Dzifa, Katchamart, Wanruchada, Kadam, Esha, Sen, Parikshit, Shinjo, Samuel Katsuyuki, Nune, Arvind, Goo, Phonpen Akarawatcharangura, Ziade, Nelly, Chen, Yi Ming, Traboco, Lisa S., Gutiérrez, Carlos Enrique Toro, Vaidya, Binit, Agarwal, Vikas, Gupta, Latika, and Nikiphorou, Elena

Published
2024
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442. Predicting and assessing the impacts of COVID-19 disruption on marine science and sectors in Australia

Author

Hobday, Alistair J., Walters, Vicki M., Stephenson, Robert L., Baylis, Shane, Bessey, Cindy, Boschetti, Fabio, Bulman, Catherine, Contardo, Stephanie, Dambacher, Jeffrey M., Day, Jemery, Dowling, Natalie A., Dunstan, Piers, Eveson, J. Paige, Farley, Jessica H., Green, Mark, Fulton, Elizabeth A., Grewe, Peter, Kunnath, Haris, Lenton, Andrew, Mackay, Mary, McDonald, Karlie S., Melbourne-Thomas, Jess, Moeseneder, Chris, Pascoe, Sean, Patterson, Toby A., Pethybridge, Heidi, Plagányi, Éva E., Scheufele, Gabriela, Schuyler, Qamar, Strzelecki, Joanna, Thomson, Robin, van Putten, E. Ingrid, and Wilcox, Chris

Published
2024
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448. Angiotensin-(1–7) decreases inflammation and lung damage caused by betacoronavirus infection in mice

Author

Lima, Erick Bryan de Sousa, Carvalho, Antônio Felipe S., Zaidan, Isabella, Monteiro, Adelson Héric A., Cardoso, Camila, Lara, Edvaldo S., Carneiro, Fernanda S., Oliveira, Leonardo C., Resende, Filipe, Santos, Felipe Rocha da Silva, Souza-Costa, Luiz Pedro, Chaves, Ian de Meira, Queiroz-Junior, Celso M., Russo, Remo C., Santos, Robson A. S., Tavares, Luciana P., Teixeira, Mauro M., Costa, Vivian V., and Sousa, Lirlândia P.

Published
2024
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