387 results on '"Yoram Kluger"'
Search Results
352. A novel approach to military combat trauma education
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Yehuda Danon, Yoel Donchin, Yoram Kluger, Asher Shushan, Avraham I. Rivkind, and Netta Notzer
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medicine.medical_specialty ,Analysis of Variance ,business.industry ,Cognition ,Traumatology ,Critical Care and Intensive Care Medicine ,Test (assessment) ,Military medicine ,Officer ,Nursing ,medicine ,Emergency Medicine ,Methods ,Wounds and Injuries ,Surgery ,Education, Medical, Continuing ,Curriculum ,Israel ,business ,Military Medicine ,Educational program ,Graduation - Abstract
A heterogeneous group of 77 physicians on compulsory or reserve military service were exposed to a 5-day course in trauma management, specifically designed for military medical personnel. Cognitive knowledge of trauma care delivery of the medical officers was assessed by means of multiple-choice written tests, which were held before and upon completion of the course. The significantly improved (p less than 0.0001) scores of the post-course test demonstrate the value of a condensed trauma educational program. Analysis of the background variants (i.e., medical education, military, and residency training, and time since graduation) revealed that the relatively short but intensive course sufficed to surmount the difficulties inherent in instructing a student body composed of individuals with dissimilar professional experience. We advocate the institution of a compact course in trauma treatment, with the specific aim of enhancing the medical officer's knowledge in this critical field of medical care.
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- 1991
353. Morgagni Hernia: Unique Presentations in Elderly Patients
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Joseph M. Klausner, A. Ravid, Yoram Kluger, Dina Lev-Chelouche, and M. Michowitz
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Aged, 80 and over ,Hernia, Diaphragmatic ,Male ,medicine.medical_specialty ,business.industry ,General surgery ,Gastroenterology ,Diaphragmatic breathing ,Aspiration pneumonia ,Pneumonia, Aspiration ,medicine.disease ,digestive system diseases ,Surgery ,Late presentation ,stomatognathic diseases ,surgical procedures, operative ,medicine ,Respiratory muscle ,Humans ,Female ,Hernia ,Hernias, Diaphragmatic, Congenital ,Respiratory Insufficiency ,business ,Aged - Abstract
We present case reports of 2 patients who were admitted to our ward for complications of Morgagni hernias. Both patients were elderly. Morgagni hernia is a rare condition. Its unique and late presentation are presented and discussed.
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- 1999
354. Traumatic Intratumoral Hemorrhage Secondary to Ventriculoperitoneal Shunt
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Felix Umansky, Yoram Kluger, John M. Gomori, and Shlomo Constantini
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- 1990
355. Vaginal Evisceration Resulting from a Water-Slide Injury
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Ronen Rub, Yoav Avidor, and Yoram Kluger
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Adult ,medicine.medical_specialty ,Hernia ,Injury control ,business.industry ,Accident prevention ,medicine.medical_treatment ,Poison control ,Surgery ,Intestinal Diseases ,Vaginal evisceration ,Swimming Pools ,medicine.anatomical_structure ,Vaginal disease ,Intestine, Small ,Vagina ,medicine ,Humans ,Recreation ,Female ,Peritoneum ,business ,Evisceration (ophthalmology) - Abstract
A case of vaginal evisceration resulting from sliding on a water chute is described. The treatment and mechanism of this rare injury are discussed.
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- 1998
356. [Untitled]
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Ami Mayo and Yoram Kluger
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business.industry ,Mass casualty event ,Mass Casualty ,social sciences ,Criminology ,medicine.disease ,Strategic bombing ,humanities ,Blast injury ,Preparedness ,Terrorism ,Emergency Medicine ,medicine ,Surgery ,business - Abstract
Bombings and explosion incidents directed against innocent civilians are the primary instrument of global terror. In the present review we highlight the major observations and lessons learned from these events. Five mechanisms of blast injury are outlined and the different type of injury that they cause is described. Indeed, the consequences of terror bombings differ from those of non-terrorism trauma in severity and complexity of injury, and constitute a new class of casualties that differ from those of conventional trauma. The clinical implications of terror bombing, in treatment dilemmas in the multidimensional injury, ancillary evaluation and handling of terror bombing mass casualty event are highlighted. All this leads to the conclusion that thorough medical preparedness to cope with this new epidemic is required, and that understanding of detonation and blast dynamics and how they correlate with the injury patterns is pivotal for revision of current mass casualty protocols.
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- 2006
357. [Untitled]
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Sandro B Rizoli, Kenneth D Boffard, Bruno Riou, Brian Warren, Philip Iau, Yoram Kluger, Rolf Rossaint, Michael Tillinger, and NovoSeven STUDY Group
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medicine.medical_specialty ,Blood transfusion ,biology ,business.industry ,medicine.medical_treatment ,Critical Care and Intensive Care Medicine ,medicine.disease ,Surgery ,Blood product ,Recombinant factor VIIa ,Anesthesia ,Cryoprecipitate ,Intensive care ,Coagulopathy ,medicine ,biology.protein ,Fresh frozen plasma ,business ,Whole blood - Abstract
We conducted a post-hoc analysis on the effect of recombinant factor VIIa (rFVIIa) on coagulopathic patients from two randomized, placebo-controlled, double-blind trials of rFVIIa as an adjunctive therapy for bleeding in patients with severe trauma. Blunt and penetrating trauma patients were randomly assigned to rFVIIa (200 + 100 + 100 μg/kg) at 0, 1, and 3 hours after transfusion of 8 units of red blood cells (RBCs) or to placebo. Subjects were monitored for 48 hours post-dosing and followed for 30 days. Coagulopathy was retrospectively defined as transfusion of fresh frozen plasma (FFP) (>1 unit of FFP per 4 units of RBCs), FFP in addition to whole blood, and transfusion of platelets and/or cryoprecipitate. Sixty rFVIIa-treated and 76 placebo subjects were retrospectively identified as being coagulopathic. No significant differences were noted in baseline characteristics. The rFVIIa-treated coagulopathic subgroup consumed significantly less blood product: RBC transfusion decreased by 2.6 units for the whole study population (P = 0.02) and by 3.5 units among patients surviving more than 48 hours (P < 0.001). Transfusion of FFP (1,400 versus 660 ml, P < 0.01), platelet (300 versus 100 ml, P = 0.01), and massive transfusions (29% versus 6%, P < 0.01) also dropped significantly. rFVIIa reduced multi-organ failure and/or acute respiratory distress syndrome in the coagulopathic patients (3% versus 20%, P = 0.004), whereas thromboembolic events were equally present in both groups (3% versus 4%, P = 1.00). Coagulopathic trauma patients appear to derive particular benefit from early adjunctive rFVIIa therapy.
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- 2006
358. [Untitled]
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Yoram Kluger, K Boffard, Rolf Lefering, Philip Iau Tsau Choong, Stephen Morris, Bruno Riou, Michael C. Christensen, Sandro Rizoli, and Rolf Rossaint
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medicine.medical_specialty ,business.industry ,Incidence (epidemiology) ,Significant difference ,Cost-effectiveness analysis ,Critical Care and Intensive Care Medicine ,law.invention ,Bleeding control ,law ,Blunt trauma ,Anesthesia ,Emergency medicine ,Activated factor VII ,Recombinant DNA ,Medicine ,business ,Cause of death - Abstract
Uncontrollable bleeding is a leading cause of death in trauma patients and a major cause of preventable morbidity and mortality. Recombinant activated factor VII (rFVIIa) has been shown to decrease the need for red blood cell transfusion among severely injured blunt trauma patients. A significant difference in the incidence of acute respiratory distress syndrome was also observed relative to standard care together with a nonsignificant difference in mortality. While safety and efficacy of rFVIIa in trauma patients has been demonstrated, little is known about its cost-effectiveness.
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- 2006
359. [Untitled]
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Philip Tc Iau, Sandro Rizoli, Brian Warren, Thomas Klitgaard, Bruno Riou, Rene Tabanera y Palacios, Kenneth D. Boffard, Yoram Kluger, and Rolf Rossaint
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Severe bleeding ,medicine.medical_specialty ,business.industry ,MEDLINE ,macromolecular substances ,Factor VIIa ,Critical Care and Intensive Care Medicine ,law.invention ,Pharmacokinetics ,Randomized controlled trial ,law ,Internal medicine ,Activated factor VII ,Recombinant DNA ,medicine ,business ,Intensive care medicine - Abstract
Introduction Recombinant activated factor VII (rFVIIa) has been used as adjunctive therapy in trauma patients with severe bleeding. However, its pharmacokinetics profile remains unknown.
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- 2006
360. Spontaneous Thrombosis of a Splenic Pseudoaneurysm after Blunt Abdominal Trauma
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Dror, Soffer, primary, Dani, Bar-Zohar, additional, Ur, Metser, additional, and Yoram, Kluger, additional
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- 2002
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361. Increased Survival Among Severe Trauma Patients
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V. Boyko, Avraham I. Rivkind, Limor Aharonson-Daniel, Michael Stein, Yoram Kluger, Kobi Peleg, and Moshe Michaelson
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Adult ,Male ,Emergency Medical Services ,medicine.medical_specialty ,Adolescent ,Poison control ,Regional Medical Programs ,Trauma Centers ,Outcome Assessment, Health Care ,Injury prevention ,medicine ,Humans ,Hospital Mortality ,Registries ,Israel ,Child ,Survival analysis ,Aged ,Retrospective Studies ,business.industry ,Mortality rate ,Infant, Newborn ,Infant ,Retrospective cohort study ,Odds ratio ,Emergency department ,Middle Aged ,Survival Analysis ,Surgery ,Child, Preschool ,Wounds and Injuries ,Injury Severity Score ,Female ,business ,Delivery of Health Care - Abstract
Hypothesis The survival of severe trauma patients is affected by the implementation of a national trauma system, which brought about developments both at the hospital and prehospital levels during the past decade. Design A retrospective cohort study of all severely injured patients (Injury Severity Score >16) recorded in the Israeli National Trauma Registry at all level I trauma centers in Israel from January 1, 1997, to December 31, 2001. Inpatient death rates were examined overall and by subgroups. Setting The National Trauma Registry includes trauma (International Statistical Classification of Diseases, 9th Revision, Clinical Modificationdiagnosis codes 800-959) hospitalizations, patients who were transferred to or from other hospitals, and those who died in the emergency department. It excludes patients who were dead on arrival, discharged following treatment in the emergency department, and patients who do not fall into the definition of trauma. Main Outcome Measure Inpatient death. Results Seven thousand four hundred twenty-three severe trauma patients were recorded. Inpatient death rates decreased significantly from 21.6% in 1997 to 14.7% in 2001. The odds ratios of mortality in 1998 through 2001 vs 1997, adjusted for year, age, sex, penetrating injury, and severity of injury (Injury Severity Score >25), were 0.92, 0.89, 0.70, and 0.65, respectively, confirming the downward trend. Conclusions A steady significant reduction in the inpatient death rate of severe trauma patients hospitalized at all level I trauma centers in Israel between 1997 and 2001 was observed. Although a single factor that explains the reduction was not identified, it is evident that the establishment of the trauma system brought about a significant decrease in mortality. We believe that integrated cooperation of various components of the national trauma system in Israel across the years may explain the reduction.
- Published
- 2004
362. THE MULTIDIMENSIONAL INJURY PATTERN - DEFINITION, RECOGNITION AND MANAGEMENT STRATEGIES
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Yoram Kluger
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Emergency Medicine ,Critical Care and Intensive Care Medicine - Published
- 2004
363. Tension Pneumothorax - Another Presentation of Spontaneous Rupture of the Esophagus
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Yoram Kluger, Gideon Zamir, and Michael Muggia-Sullam
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Spontaneous rupture ,medicine.medical_specialty ,business.industry ,Gastroenterology ,Disease ,Chest pain ,medicine.disease ,Tension pneumothorax ,Surgery ,Sepsis ,medicine.anatomical_structure ,medicine ,Radiology ,medicine.symptom ,Esophagus ,Presentation (obstetrics) ,business - Abstract
Rupture of the esophagus is a disease with grave clinical consequences if diagnosed late. Patients usually present with chest pain and signs of sepsis. A patient is described who presented, with tensi
- Published
- 1995
364. To the Editor
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Yair Shindel, Yoram Kluger, and Ami Mayo
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medicine.medical_specialty ,business.industry ,Traumatic brain injury ,Anesthesia ,medicine ,Surgery ,Endotracheal intubation ,Critical Care and Intensive Care Medicine ,business ,medicine.disease - Published
- 2003
365. Impaled Fractured Rib
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Joseph Paz, Yoram Kluger, and B. Sagie
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Aged, 80 and over ,Rib Fractures ,business.industry ,Lung Injury ,Anatomy ,Pulmonary Artery ,Critical Care and Intensive Care Medicine ,Radiography ,Humans ,Medicine ,Female ,Surgery ,business ,Lung ,Aged - Published
- 2003
366. Letters to the Editor
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Ami Mayo and Yoram Kluger
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Surgery ,Critical Care and Intensive Care Medicine - Published
- 2003
367. ENHANCED RIM AROUND INFARCTED, TRAUMATIZED SPLEEN ON COMPUTED TOMOGRAPHIC SCANS
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Richard N. Townsend, Douglas B. Paul, Daniel L. Diamond, and Yoram Kluger
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Traumatic infarct ,medicine.medical_treatment ,Infarction ,Spleen ,Computed tomography ,Critical Care and Intensive Care Medicine ,medicine.disease ,Computed tomographic ,medicine.anatomical_structure ,Splenic vein ,Laparotomy ,cardiovascular system ,medicine ,Abdomen ,Surgery ,Radiology ,business - Abstract
Computed tomography is considered a reliable imaging technique when determining the extent of splenic injury. We present the case of a patient with a traumatic infarct of the spleen detected by computed tomographic scanning of the abdomen. During laparotomy there was an infarction of the spleen from a hilar injury in addition to bleeding from the splenic vein. We conclude that ongoing bleeding from the splenic hilar vessel can lead to a rim of enhancement around the spleen from contrast material. This should be taken into account when a decision is made for nonsurgical management.
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- 1994
368. MEDIATION OF MULTIPLE ORGAN DYSFUNCTION BY RADICAL OXYGEN SPECIES FOLLOWING REMOTE CIRCULATORY ARREST. COMMON MECHANISM OF ACTION?
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Edith Hochhauser, Avi A. Weinbroum, Yoram Kluger, Valery Rudick, and Bernardo A. Vidne
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medicine.medical_specialty ,Mechanism of action ,business.industry ,Anesthesia ,Mediation ,Circulatory system ,Organ dysfunction ,medicine ,medicine.symptom ,Intensive care medicine ,business - Published
- 1998
369. A COMPARATIVE STUDY OF SPLENIC WOUND HEALING IN AN EXPERIMENTAL MODEL IN YOUNG AND ADULT RATS
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Micha Rabau, Dan Dayan, Yoram Kluger, G. Chaushu, and Ronen Rub
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medicine.medical_specialty ,Experimental model ,business.industry ,medicine ,Wound healing ,business ,Surgery - Published
- 1998
370. Administration of amphotericin B in lipid emulsion decreases nephrotoxicity: a controlled study in critically ill patients
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Arik Setton, Yoram Kluger, H Nagar, Valery Rudick, P Halpern, A Scarlatt, A. Silbiger, P. Sorkine, Avi A. Weinbroum, and E Israitel
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medicine.medical_specialty ,Critically ill ,business.industry ,Critical Care and Intensive Care Medicine ,Nephrotoxicity ,Amphotericin B ,Emergency medicine ,Meeting Abstract ,medicine ,Lipid emulsion ,Intensive care medicine ,business ,Administration (government) ,medicine.drug - Published
- 1997
371. Intraoperative cholangiogram-induced bradycardia—another indication for common bile duct exploration
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Oded Jurim, Zvi Gimmon, and Yoram Kluger
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Bradycardia ,medicine.medical_specialty ,Common bile duct exploration ,Physiology ,business.industry ,General surgery ,Gastroenterology ,Hepatology ,Transplant surgery ,Internal medicine ,Intraoperative cholangiogram ,medicine ,medicine.symptom ,business - Published
- 1995
372. Embolization of transected vertebral arteries in unstable trauma patients.
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Eli Atar, Igal Griton, Gil N. Bachar, Gabriel Bartal, Yoram Kluger, and Alexander Belenky
- Abstract
Abstract The aim of this paper is to report our experience with coil embolization for the treatment of vertebral artery transection in unstable trauma patients. The course of four patients admitted to our units between 1998 and 2003 with traumatic injuries of the upper thorax or neck is described. All had unstable hemodynamic parameters at presentation. Emergent arteriogram revealed vertebral artery transection, which was managed by immediate coil embolization proximal to the injury site. Initial technical success was achieved in all four patients, with hemodynamic improvement. No further treatment or surgery to control the vessel injury was needed. There were no immediate or late complications of the procedure and no neurological sequelae. Emergency coil embolization is an effective endovascular technique for use in unstable patients with angiography findings of a transected vertebral artery. [ABSTRACT FROM AUTHOR]
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- 2005
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373. Functions and principles in the management of bombing mass casualty incidents: lessons learned at the Tel-Aviv Souraski Medical Center.
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Yoram Kluger
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- 2004
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374. LAWN AND GARDEN TRACTOR ACCIDENTS
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Yoram Kluger and Douglas B. Paul
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Male ,Tractor ,business.product_category ,Injury control ,business.industry ,Human factors and ergonomics ,Lawn ,Poison control ,Middle Aged ,Critical Care and Intensive Care Medicine ,medicine.disease ,Suicide prevention ,Occupational safety and health ,Accidents, Home ,Injury prevention ,Humans ,Wounds and Injuries ,Medicine ,Surgery ,Medical emergency ,business ,Aged ,Retrospective Studies - Published
- 1993
375. Pelvic Suspension for the Management of Complicated Perineal Wounds
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Yoram Kluger, Ricard N. Townsend, Jarosz Da, and Dickson Cs
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medicine.medical_specialty ,business.industry ,medicine ,Humans ,Wounds and Injuries ,Surgery ,Beds ,Perineum ,Critical Care and Intensive Care Medicine ,business ,Suspension (vehicle) - Published
- 1992
376. Traumatic intratumoral hemorrhage secondary to a ventriculoperitoneal shunt
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Shlomo Constantini, Felix Umansky, John M. Gomori, and Yoram Kluger
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Male ,medicine.medical_specialty ,business.industry ,Infant ,Obstructive hydrocephalus ,General Medicine ,medicine.disease ,Cerebrospinal Fluid Shunts ,Hydrocephalus ,Shunt (medical) ,Surgery ,Shunting ,Pediatrics, Perinatology and Child Health ,Humans ,Medicine ,Neurology (clinical) ,Derivation ,Neurosurgery ,Oligodendroglioma ,Peritoneum ,business ,Complication ,Cerebral Hemorrhage - Abstract
We report a case of a 14-month-old boy with a primary intraventricular oligodendroglioma and obstructive hydrocephalus. The child underwent a bilateral ventriculoperitoneal shunt and developed a massive and fatal intratumoral hemorrhage initiated by a mild trauma when introducing the left ventricular catheter. To our knowledge, this is the first report in the literature of such a complication during a shunting procedure for obstructive hydrocephalus of tumoral origin.
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- 1988
377. The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper
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Jae Gil Lee, Ernest E. Moore, Sanjay Gupta, Raul Coimbra, Sanjay Marwah, Salomone Di Saverio, Ari Leppäniemi, Wagih Ghnnam, Gustavo Pereira Fraga, Maria Paula Garcia, Walter L. Biffl, Zaza Demetrashvili, Luca Ansaloni, Martin D. Zielinski, Frederick A. Moore, Massimo Sartelli, Reinhold Kafka-Ritsch, Ewen A. Griffiths, Rifat Latifi, Fausto Catena, Yoram Kluger, Carlos A. Ordoñez, Gerson Alves Pereira, H. Plaudis, Miklosh Bala, Federico Coccolini, Sanoop K. Zachariah, Demetrios Demetriades, Michael McFarlane, Victor Y. Kong, Marcelo A. Beltrán, Jan Ulrych, Andreas Hecker, Vishal G Shelat, Fikri M. Abu-Zidan, Osvaldo Chiara, Aleksandar Karamarkovic, and Jose J. Diaz
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Damage control ,medicine.medical_specialty ,Abdominal compartment syndrome ,business.industry ,Peritoneal fluid ,Review ,Anastomosis ,medicine.disease ,Bioinformatics ,3. Good health ,Surgery ,Sepsis ,Abdominal wall ,medicine.anatomical_structure ,Abdominal trauma ,Damage control surgery ,medicine ,Emergency Medicine ,business - Abstract
The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients with severe abdominal sepsis, however its precise role in these patients is still not clear. In severe abdominal sepsis the OA may allow early identification and draining of any residual infection, control any persistent source of infection, and remove more effectively infected or cytokine-loaded peritoneal fluid, preventing abdominal compartment syndrome and deferring definitive intervention and anastomosis until the patient is appropriately resuscitated and hemodynamically stable and thus better able to heal. However, the OA may require multiple returns to the operating room and may be associated with significant complications, including enteroatmospheric fistulas, loss of abdominal wall domain and large hernias. Surgeons should be aware of the pathophysiology of severe intra-abdominal sepsis and always keep in mind the option of using open abdomen to be able to use it in the right patient at the right time.
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378. 2016 WSES guidelines on acute calculous cholecystitis
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Sanjay Gupta, Fausto Catena, Giuseppe Borzellino, Gustavo Pereira Fraga, Dario Piazzalunga, Pierluigi Viale, Cino Bendinelli, Rifat Latifi, Philip F. Stahel, Imtiaz Wani, Kurinchi Selvan Gurusamy, M. De Moya, Yoram Kluger, G. Camapanelli, Clay Cothren Burlew, Zsolt J. Balogh, V. Koka, Ari Leppäniemi, Luigi Bonavina, Ferdinando Agresta, Federico Coccolini, Walter L. Biffl, Monica Ceresoli, Francesco Brunetti, M. D. Kelly, Boris Sakakushev, I. Bailey, Jeffry L. Kashuk, Rao R. Ivatury, Ian Civil, H. Jeekel, R. V. Maier, Gregorio Tugnoli, Luca Ansaloni, Fabio Cesare Campanile, Osvaldo Chiara, S. Uraneus, Massimo Sartelli, George C. Velmahos, A. B. Peitzmann, Michael Sugrue, Raul Coimbra, S. Di Saverio, Abe Fingerhut, Ernest E. Moore, Thomas M. Scalea, Korhan Taviloğlu, Ingo Marzi, Andrea Allegri, M. Pisano, F. A. Moore, Dieter G. Weber, Ansaloni, L, Pisano, M, Coccolini, F, Peitzmann, A, Fingerhut, A, Catena, F, Agresta, F, Allegri, A, Bailey, I, Balogh, Z, Bendinelli, C, Biffl, W, Bonavina, L, Borzellino, G, Brunetti, F, Burlew, C, Camapanelli, G, Campanile, F, Ceresoli, M, Chiara, O, Civil, I, Coimbra, R, De Moya, M, Di Saverio, S, Fraga, G, Gupta, S, Kashuk, J, Kelly, M, Koka, V, Jeekel, H, Latifi, R, Leppaniemi, A, Maier, R, Marzi, I, Moore, F, Piazzalunga, D, Sakakushev, B, Sartelli, M, Scalea, T, Stahel, P, Taviloglu, K, Tugnoli, G, Uraneus, S, Velmahos, G, Wani, I, Weber, D, Viale, P, Sugrue, M, Ivatury, R, Kluger, Y, Gurusamy, K, Moore, E, and Neurosciences
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medicine.medical_specialty ,Biliary tree stone ,030230 surgery ,03 medical and health sciences ,0302 clinical medicine ,Diagnosis ,medicine ,Cholecystectomy ,ddc:610 ,Biliary tree stones ,Abdominal infections ,Acute calcolous cholecystitis ,Antibiotic ,Endoscopic ultrasound ,Gallbladder percutaneous drainage ,Magnetic resonance ,Surgical risk ,business.industry ,General surgery ,Gastroenterology ,Abdominal infection ,Acute calcolous cholecystiti ,medicine.disease ,Dermatology ,3. Good health ,Cholecystitis ,Emergency Medicine ,030211 gastroenterology & hepatology ,Surgery ,business ,Diagnosi - Abstract
Acute calculus cholecystitis is a very common disease with several area of uncertainty. The World Society of Emergency Surgery developed extensive guidelines in order to cover grey areas. The diagnostic criteria, the antimicrobial therapy, the evaluation of associated common bile duct stones, the identification of “high risk” patients, the surgical timing, the type of surgery, and the alternatives to surgery are discussed. Moreover the algorithm is proposed: as soon as diagnosis is made and after the evaluation of choledocholitiasis risk, laparoscopic cholecystectomy should be offered to all patients exception of those with high risk of morbidity or mortality. These Guidelines must be considered as an adjunctive tool for decision but they are not substitute of the clinical judgement for the individual patient.
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379. World Society of Emergency Surgery-indication of globalism and renaissance through the 2015 biennial assembly
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Fausto Catena, Luca Ansaloni, Yoram Kluger, and Jeffry L. Kashuk
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Medical education ,medicine.medical_specialty ,Enthusiasm ,Evidence-based practice ,business.industry ,media_common.quotation_subject ,Attendance ,Specialty ,Presentation ,Promotion (rank) ,Emergency medicine ,Commentary ,medicine ,Emergency Medicine ,Surgery ,Mission statement ,Personal experience ,business ,media_common - Abstract
The World Society of Emergency Surgery (WSES) was established in 2007. The objectives set forth by the society, as enumerated in the mission statement, is: “The overall goals include the promotion of the specialty of emergency surgery as part of the emerging discipline of acute care surgery via academic exchange in an effort to further training and education as well as translational research in the specialty’. The first WSES international assembly took place in Sardinia, Italy in 2011 and the second in Bergamo, Italy, in 2013. The 3rd international congress of WSES was held in Jerusalem, Israel, 5–8 July, 2015. As this was the first meeting outside of Italy, it represented an important worldwide extension of the society, with over 23 countries being represented by over 150 attendees. A pre- congress educational course on IAI (intra-abdominal infections) preceded the academic gathering, attended by 20 residents in training who enthusiastically participated and successfully completed the course. The residents were provided with a certificate of attendance by the WSES IAI course directors. An important and carefully planned objective of the meeting involved presentation of evidence based guidelines for common clinical challenges such as acute appendicitis, acute cholecystitis, and acute diverticulitis. These guidelines were reached after a detailed and methodical process with involvement of many contributing physicians and institutions and summaries of the suggested guidelines were presented for the approval of the assembly. The resultant guidelines from this process will be submitted for publication in the forthcoming issues of the World Journal of Emergency Surgery. Systematic reviews of the literature were presented in plenary sessions on a multitude of topics covering the entire spectrum of Emergency Surgery, A two and half day academic meeting followed the course and included 35 position lectures and 8 WSES guidelines reports. Eighty one clinical and research based abstracts were submitted from worldwide academic institutions, and 68 were presented in parallel sessions. Seven outstanding abstracts were chosen by the scientific committee and were presented in a plenary session. The assembly than nominated the three best abstract (1rd -3rd places) using an electronic voting system. The first authors of these abstracts were respected with a certificate signed by the congress chairmen. Besides discussions of the surgical approach to a many clinical challenges, state of the art strategies dealing with virtually all areas of surgical emergencies were comprehensively discussed. Thought-provoking case discussions presented during the meeting provided a great opportunity to share extensive knowledge and personal experiences from esteemed colleagues worldwide. Being a young society, the excitement generated by the meeting in Jerusalem reflected the dedication of its members to the specialty and generated new interest by a broader group of young surgeons and trainees. While the 2015 WSES meeting was termed “The Last of the Mohicans? - the General Surgeon of 2015?”, the keen support of many young surgeons suggests that indeed there is much enthusiasm and hope for the future of the specialty of Emergency Surgery. The executive board voted to host the next meeting, in 2017, in Brazil. We look forward to seeing everyone there as the congress moves to the American continent for the first time. Please join us at the new WSES web site (www.wses.org.uk) and in all the society activities (WSES registries, multi-center trails, courses and meetings). Your membership in the society is important.
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380. Erratum to: caustic ingestion management: world society of emergency surgery preliminary survey of expert opinion
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Ofir Ben Ishay, Luca Ansaloni, Ernest E. Moore, Luigi Bonavina, Carlos Augusto Gomez, Augustin Goran, Wagih Ghnnam, Salomone Di Saverio, Ari Leppäniemi, Gustavo Pereira Fraga, Chirica Mircea, Damien Massalou, Walter L. Biffl, Yoram Kluger, Sanjay Marwah, Miklosh Bala, Massimo Sartelli, Fausto Catena, Amit Katz, and Jeffry L. Kashuk
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medicine.medical_specialty ,Emergency surgery ,business.industry ,Expert opinion ,medicine ,Emergency Medicine ,Surgery ,Medical emergency ,business ,medicine.disease ,Caustic ingestion - Full Text
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381. A Multidisciplinary survey on controversies in the use of EUS-guided FNA: assessing perspectives of surgeons, oncologists and gastroenterologists
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Jesse Lachter, Yoram Kluger, and Yoav Rosenthal
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medicine.medical_specialty ,Attitude of Health Personnel ,Biopsy, Fine-Needle ,MEDLINE ,Multidisciplinary team ,Endosonography ,Multidisciplinary approach ,Surveys and Questionnaires ,Humans ,Medicine ,Practice Patterns, Physicians' ,lcsh:RC799-869 ,skin and connective tissue diseases ,Pancreas ,Ultrasonography, Interventional ,Practice patterns ,business.industry ,General surgery ,Gastroenterology ,General Medicine ,Biopsy fine needle ,medicine.disease ,digestive system diseases ,Pancreatic Neoplasms ,body regions ,medicine.anatomical_structure ,surgical procedures, operative ,lcsh:Diseases of the digestive system. Gastroenterology ,Radiology ,Pancreatic cysts ,Ultrasonography ,business ,Research Article - Abstract
Background EUS-guided FNA can help diagnose and differentiate between various pancreatic and other lesions. The aim of this study was to compare approaches among involved/relevant physicians to the controversies surrounding the use of FNA in EUS. Methods A five-case survey was developed, piloted, and validated. It was collected from a total of 101 physicians, who were all either gastroenterologists (GIs), surgeons or oncologists. The survey compared the management strategies chosen by members of these relevant disciplines regarding EUS-guided FNA. Results For CT operable T2NOM0 pancreatic tumors the research demonstrated variance as to whether to undertake EUS-guided FNA, at p < 0.05. For inoperable pancreatic tumors 66.7% of oncologists, 62.2% of surgeons and 79.1% of GIs opted for FNA (p < 0.05). For cystic pancreatic lesions, oncologists were more likely to send patients to surgery without FNA. For stable simple pancreatic cysts (23 mm), most physicians (66.67%) did not recommend FNA. For a submucosal gastric 19 mm lesion, 63.2% of surgeons recommended FNA, vs. 90.0% of oncologists (p < 0.05). Conclusions Controversies as to ideal application of EUS-FNA persist. Optimal guidelines should reflect the needs and concerns of the multidisciplinary team who treat patients who need EUS-FNA. Multi-specialty meetings assembled to manage patients with these disorders may be enlightening and may help develop consensus.
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382. Potential benefits of an integrated military/civilian trauma system: experiences from two major regional conflicts
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Irina Radomislensky, Yoram Kluger, Adi Givon, Kobi Peleg, Elon Glassberg, and Jeffry L. Kashuk
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Male ,Warfare ,medicine.medical_specialty ,0211 other engineering and technologies ,Poison control ,Traumatology ,02 engineering and technology ,Critical Care and Intensive Care Medicine ,Military medicine ,03 medical and health sciences ,Injury Severity Score ,0302 clinical medicine ,Trauma Centers ,Injury prevention ,Humans ,Medicine ,Hospital Mortality ,Registries ,Original Research Article ,Israel ,Military Medicine ,Retrospective Studies ,021110 strategic, defence & security studies ,Civilian casualties ,business.industry ,Trauma center ,030208 emergency & critical care medicine ,Triage ,Emergency medicine ,Emergency Medicine ,Wounds and Injuries ,Female ,business - Abstract
Background Although differences of opinion and controversies may arise, lessons learned from military conflicts often translate into improvements in triage, resuscitation strategies, and surgical technique. Our fully integrated national trauma system, providing care for both military and civilian casualties, necessitates close cooperation between all aspects of both sectors. We theorized that lessons learned from two regional conflicts over 8 years, with resultant improved triage, reduced hospital length of stay, and sustained low mortality would aid performance improvement and provide evidence of overall trauma system maturation. Methods We performed an 8 year, retrospective analysis of the Israeli National Trauma Registry prospective data base for all casualties presenting to level 1 and 2 trauma centers nationwide during an earlier conflict (W1) (7/12/06-8/14/06) and sought to compare results to those of a more recent war(W2), (7/08/14-08/26/14), as well as to compare our results to non-war civilian morbidity and mortality during the same time frame. Of particular interest were: casualty distributions, injuries/ISS, patterns of evacuation/triage, hospital length of stay, and mortality. Results Data on 919 war casualties was available for evaluation. Of 490 evacuated during W1, 341 (70%) were transferred to Level 1 centers, compared with 307 (72%) from the 429 casualties in W2. In W2, significantly more severe injuries (ISS ≥16) were evacuated directly to level 1 centers (42, 76% vs. 20, 43% respectively; p = 0.0007). W2 vs. W1 saw a significant increase in evacuations using helicopter (219,51% vs. 180,37%; p
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383. Convulsions Induced by Aminocaproic Acid Infusion
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Ayelet Heyman, Yoram Kluger, Eilat Shinar, and Reuben Rabinovici
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Male ,Cirrhosis ,030226 pharmacology & pharmacy ,03 medical and health sciences ,Liver disease ,0302 clinical medicine ,Seizures ,Antifibrinolytic agent ,medicine ,Humans ,Pharmacology (medical) ,In patient ,030212 general & internal medicine ,General Pharmacology, Toxicology and Pharmaceutics ,Infusions, Intravenous ,Adverse effect ,Aminocaproates ,business.industry ,Middle Aged ,medicine.disease ,Anesthesia ,Aminocaproic acid ,business ,Neurological problems ,Grand mal seizure ,medicine.drug - Abstract
Aminocaproic acid is a widely used antifibrinolytic agent. Serious adverse effects associated with its use are rare, but we report on a patient with liver disease and cirrhosis who experienced a grand mal seizure during the intravenous administration of aminocaproic acid. Clinicians should be alert to the occurrence of this adverse effect in patients with no previous neurological problems.
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- 1989
384. Utility of routine blood tests after elective laparoscopic cholecystectomy for symptomatic gallstones.
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Ben-Ishay O, Zeltser M, and Kluger Y
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Aim: To evaluate the value of blood testing after elective laparoscopic cholecystectomy and its association with procedure related complications., Methods: Charts of all patients undergoing elective laparoscopic cholecystectomy from January 2013 through December 2014 were reviewed retrospectively for demographics, indication for surgery, operative course and outcome. In our institution the decision to perform postoperative blood analysis is left for the discretion of the surgeon, therefore we had the possibility to compare the results of those who had blood analyses results to those who did not. Analysis was performed to identify variables associated with the decision to perform postoperative blood tests. Subsequently a univariate and multivariate analyses was performed comparing the two cohorts. Secondary subgroup analysis was performed to identify factors associated with procedure related complications., Results: Five hundred and thirty-two elective laparoscopic cholecystectomies for symptomatic gallstones were performed during the study period. Sixty-four percent of the patients ( n = 340) had blood tests taken post operatively. Patients that had laboratory tests taken were older ( P = 0.006, OR = 1.01), had longer surgery ( P < 0.001, OR = 3.22) had more drains placed ( P < 0.001, OR = 3.2) and stayed longer in the hospital ( P < 0.001, OR = 1.2). A subgroup analysis of the patients who experienced complications revealed longer stay in the hospital ( P < 0.001), higher body mass index (BMI) ( P = 0.04, OR = 1.08), increased rates of drain placement ( P = 0.006, OR = 3.1) and higher conversion rates ( P = 0.01, OR = 14.6). Postoperative blood tests withdrawals were not associated with complications ( P = 0.44). On Multivariate analysis BMI and drain placement were independently associated with complications., Conclusion: The current study indicate that routine postoperative blood tests after elective laparoscopic cholecystectomy for symptomatic gallstones does not predict complications and may have an added benefit in diagnosis and management of cases were the surgeon encountered true technical difficulty during surgery., Competing Interests: Conflict-of-interest statement: The authors declare no conflict of interest.
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- 2017
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385. IgG4-related disease manifesting as an acute gastric-pericardial fistula.
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Frydman J, Grunner S, and Kluger Y
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- Acute Disease, Aged, Autoimmune Diseases blood, Autoimmune Diseases diagnosis, Autoimmune Diseases surgery, Biomarkers blood, Drainage, Esophagostomy, Gastrectomy, Gastric Fistula blood, Gastric Fistula diagnosis, Gastric Fistula surgery, Heart Diseases blood, Heart Diseases diagnosis, Heart Diseases surgery, Humans, Jejunostomy, Male, Stomach Ulcer blood, Stomach Ulcer diagnosis, Stomach Ulcer surgery, Tomography, X-Ray Computed, Treatment Outcome, Autoimmune Diseases immunology, Gastric Fistula immunology, Heart Diseases immunology, Immunoglobulin G blood, Pericardium surgery, Stomach Ulcer immunology
- Abstract
IgG4-related disease is a recently recognized entity linked initially to autoimmune pancreatitis and has been subsequently described in nearly every organ system. Men over the age of 50 represent the most affected demographic group and a comprehensive set of diagnostic criteria has been developed to aid treating clinicians. Though elevated levels of IgG4 in the serum are suggestive of the disease, definitive diagnosis is made on histopathology. Treatment is tailored to the clinical presentation with corticosteroid therapy known to have proven efficacy. Gastric manifestations of the IgG4-related disease primarily come in two varieties, notably chronic ulceration or pseudotumor formation. Autoimmune pancreatitis conveys increased risk for IgG4-related disease of the stomach, which is independent of Helicobacter pylori status. In this case report, we present an acute gastric-pericardial fistula secondary to IgG4-related disease that required urgent operative management. To our knowledge, this is the first report in the medical literature describing this complication of IgG4-related disease.
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- 2014
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386. Clinical presentation predicts the outcome of patients with colon cancer.
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Ben-Ishay O, Peled Z, Othman A, Brauner E, and Kluger Y
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Aim: To elucidate the relationship between clinical presentation and outcome., Methods: A single institution retrospective chart review of patients admitted with the diagnosis of colon cancer. We used univariate and a multivariate analysis to identify symptoms association with mortality. An odds ratio based clinical score was created to evaluate the contribution of the quality of symptoms to outcome. Primary measure of outcome was survival., Results: During the study period, 236 patients met the inclusion criteria. Overall survival was 60.6%, mean follow-up 3.0 years. A bivariate analysis showed that increasing number of symptoms is not associated with mortality. However, a symptom-specific analysis performed using a logistic regression model controlling for age, stage and the duration of complaints revealed that the presence of melena was independently associated with mortality [P = 0.04, odds ratio (OR) 7.4], while rectal bleeding was associated with survival (P = 0.004, OR 3.9). Applying the proposed clinical score to an receiver operating characteristic curve showed that score > 1 had a strong association with mortality. The same logistic regression model was applied. The results showed that a score > 1 was an independent predictor of mortality (P < 0.001) and associated with node-positive disease (P = 0.008)., Conclusion: The quality of symptoms rather than quantity is correlated with outcome among patients with colon cancer. The proposed clinical scoring system may correctly predict the patient's outcome.
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- 2013
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387. Autoimmune pancreatitis misdiagnosed as a tumor of the head of the pancreas.
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Brauner E, Lachter J, Ben-Ishay O, Vlodavsky E, and Kluger Y
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Autoimmune pancreatitis can mimic pancreatic cancer in its clinical presentation, imaging features and laboratory parameters. Differentiating between those two entities requires implementation of clinical judgment and experience along with objective parameters that may suggest either condition. Few strategies have been proposed for the surgeon to implement when facing borderline cases. The following case is an example of a clinical scenario compatible with an accepted algorithm for diagnosis of pancreatic cancer, which eventually proved wrong. We present a 75-year-old patient who was admitted for obstructive jaundice. Imaging features were highly suggestive for pancreatic cancer as was the carbohydrate antigen 19-9 (CA 19-9) level, leading to a decision for surgery. Pathological examination revealed autoimmune pancreatitis. Though no frank carcinoma was found, premalignant ductal changes of pancreatic intraepithelial neoplasia (PanIN) I and PanIN II were discovered throughout the pancreatic duct. Caution is advised when relying on the combination of highly suggestive radiology features and elevated levels of CA 19-9 in the diagnosis of pancreatic cancer. When the tissue diagnosis is not conclusive, obtaining IgG4 and antinuclear Ab levels is advised, to rule out the rare possibility of autoimmune pancreatitis. Patients with autoimmune pancreatitis should be followed carefully as precancerous lesions may accompany the benign disease and the correlation of these two entities has not been ruled out.
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- 2012
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