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Produk pencernaan tubuh disalurkan dan dikeluarkan oleh ginjal. Berkurangnya fungsi ginjal akan mengganggu keseimbangan tubuh sehingga menyebabkan penumpukan produk limbah terutama urea (yang menyebabkan uremia), gangguan keseimbangan cairan, serta kelebihan cairan dan elektrolit. Pasien yang menjalani terapi hemodialisa dapat mengalami efek samping psikis dan fisik. Tujuan penelitian adalah untuk mengetahui hubungan depresi dengan kelelahan pada pasien yang menjalani hemodialisa. Dalam studi cross-sectional ini, 43 peserta dipilih secara acak. Kuesioner untuk mengukur tingkat kelelahan menggunakan Fatigue Severity Scale (FSS) dan Beck Depression Inventory (BDI) untuk menilai gejala depresi. Penelitian ini menggunakan uji non parametrik dengan Spearman Rank. Hasil penelitian menjelaskan bahwa 14 responden yang menjalani hemodialisis mengalami depresi ringan dan kelelahan. Dari hasil tersebut diperoleh nilai signifikansi sebesar 0,005 dan nilai korelasi Sperma sebesar 0,422. Kesimpulannya, data menunjukkan adanya korelasi positif dengan kekuatan sedang antara tingkat kelelahan dan depresi yang dialami pasien hemodialisa. Hal ini menunjukkan bahwa semakin pasien yang menjalani hemodialisa mengalami kelelahan, maka semakin besar pula kemungkinan mereka mengalami depresi. Hasil penelitian ini dijadikan evidence based dalam melakukan intervensi dalam menangani pasien dengan gagal ginjal kronik yang mengalami fatigue serta depresi pada saat menjalani hemodialisa.

Human Resources are a generator of available resources in the activities and routine of an organization or company that the good and the bad performance of an organization are determined by the performance of human resources. Professional employee is a reliable employee with balanced quality between academic and emotional capability. Academic intelligence is frequently given a higher position than emotional intelligence is an individual evaluation. Emotional intelligence is the factor determining the effectiveness of someone is working that with high emotional intelligence, the human resources can be easily directed and guided to work in accordance with the goals of organization. The prupose of this quantitative descriptive explanatory study was to look at the influence of Emotional Quotient (EQ) and Work Stress on the performance of the employees of PT. Bank Mestika Dharma Medan using the theory of human resources management related to Emotional Quotient (EQ), work stress and work performance. The population of this study was 585 employees and 238 of them were selected to be the samples for this study. The data obtained were analyzed through multiple linear regression tests using F test to simultaneously test the hypothesis and using t test to do a partial test. The result of the hypothesis test showed that simultaneously the variable of Emotional Quotient and work stress had a significant influence on the improvemnet of the performance of the employees of PT. Bank Mestika Dharma Medan

ABSTRACT Karimunjawa National Park is one of the national parks that have the objective to maintain fish populations in the Java Sea, where one of them is grouper. Grouper is one of the target fish in the national park. The objective of this study is to assess the conditions and dynamics of the grouper fishery in Karimunjawa National Park. Fish landing surveys were conducted to collect the data. Fishing gear types, grouper species, and weight of each species were collected. Calculation of Catch per Unit Effort (CPUE) per month and two-way ANOVA statistical tests were used for data analysis. Results of this study indicated that catches of grouper using speargun was significantly higher than the catch using handline. There was a seasonal cycle of the grouper catch, where the value of the highest CPUE occurred in transitional season between the west and east monsoon season, from March to May. Key words: CPUE, grouper fishery, Karimunjawa National Park ------- ABSTRAK Taman Nasional Karimunjawa merupakan salah satu taman nasional yang salah satu tujuannya untuk mempertahankan populasi ikan di Laut Jawa, dimana salah satunya adalah perikanan kerapu. Ikan kerapu merupakan salah satu target penangkapan di perairan Taman Nasional Karimunjawa. Tujuan penelitian ini adalah mengetahui kondisi dan dinamika perikanan kerapu di Taman Nasional Karimunjawa. Survei pendaratan ikan dilakukan untuk pengumpulan data. Data yang dikumpulkan dalam penelitian ini adalah alat tangkap yang digunakan untuk menangkap ikan kerapu, jenis hasil tangkapan, dan berat masing-masing jenis hasil tangkapan setiap trip. Perhitungan nilai Catch per Unit Effort (CPUE) setiap bulan dan uji statistik two ways ANOVA digunakan untuk analisis data. Hasil penelitian ini menunjukkan bahwa hasil tangkapan ikan kerapu dengan menggunakan speargun lebih tinggi dan berbeda nyata secara statistik dibandingkan hasil tangkapan dengan menggunakan pancing. Terdapat siklus musiman hasil tangkapan, dimana nilai CPUE tertinggi terjadi pada musim peralihan antara musim barat dan musim timur yakni dari bulan Maret hingga Mei. Kata kunci: CPUE, perikanan kerapu, Taman Nasional Karimunjawa

A simple and rapid densitometric method has been developed for determination of low levels of carbaryl in soy bean matrix samples.Sample carbaryl in the soybean matrix was extracted with acetonitril, chloroform and NaCl 0.2 % solution, and the resulting chloroformlayer was separated, added sodium sulphate anhydrous to get free of water than evaporated. After dissolution in methanol, the solutionswere spotted on silica gel GF254 plates which were then eluted with toluene: ethyl acetate = 3:1 (v/v). Quantitative evaluation wasperformed by measuring the absorbance reflectance of the analyte spots at λ 280 nm. This densitometric method is selective, precise,accurate and can be used for the determination carbaryl in soy bean matrix.Key words: carbaryl, TLC-densitometry, validation methode, soy bean

Messages in a mural are delivered through the processing of visual elements embedded with symbols, signs, codes, and meanings. The messages delivered in the mural comprise both verbal and visual. The existence of murals created the concept of social space which includes important issues such as the theme of disaster. When the mural is associated with disaster mitigation efforts, the mural is expected to bring a great influence on the awareness of citizens. The mural is also expected as a monument that can urge citizens to stay alert to potential disasters. The research methodology is a descriptive-explanative method with a qualitative approach. This research aims to analyze and explain the causal relationships in the production of social space through a mural with the theme of disaster. The results show that the existence of disaster-themed mural can be included in three dimensions of social space production according to Lafebvre, namely spatial space where the social activities of artists in making the mural on the walls of the city that originally serves mere as a barrier. Mural in the middle of the city is a representation of space because the discourse used in producing social space is a social problem that exists around the mural space was created so that the meaning contained in the mural is able to represent.

Educational technology is an applied scientific discipline that develops by the need of the field , namely the demands of learning more effectively, efficiently, broadly, widely, and quickly. As a systematic and systematic process in helping to solve learning problems, the application of educational technology can be directed to the learning quality assurance process. This study is aimed at: (1) analyzing the application of educational technology in improving the quality of learning in universities, (2) analyzing the quality assurance process of learning in universities, and (3) testing the effectiveness of quality assurance models based on applied educational technology in improving the quality of learning in College. The method used is a quantitative approach. The study began with an exploratory survey method, then continued with experiments. The results showed that the analysis of the quality of learning in universities was very dependent on the application of educational technology, the learning quality assurance process agreed that educational technology could improve the quality of learning in universities, and the application of quality assurance models based on applied learning technology is effective to improve the quality of learning in college high. The benefits of this study as a reference for the development model of quality assurance, especially for education and learning.

In order to meet the goal of environmental education, creating generation who are environmentally concerned and responsible, Ar Ridho Nature School Semarang (SAA), put the message of such education on their gardening subject. The subject has designed for grade 1 to 6 as the school commitment to build a civilization who are able to live in harmony with nature. The purpose of gardening is not only giving students environmental knowledge but also building environmental awareness and skill to preserve nature. Thus, this study aims at presenting environmental awareness among students of SAA and finding out whether there is a relationship between environmental knowledge and environmental awareness. The third grade of students were selected as participants since they were in the middle level of elementary education which has not applied 2013 Curricula (K13). A questionnaire survey was applied to 62 students face to face with considering the level of students for understanding the given questions. Descriptive statistics, ANOVA, and Pearson coefficient of correlation are the techniques used to analyze the data.

Job performance for a nurse is very important. One effort to improve job performance is by following training and develop the job characteristics. Langsa DistrictGeneral Hospital has striven to enhance the job performance for the nurses through training and development of job characteristics, but there is no equality in training and for all nurses and they do not have positive attitudes toward job characteristics, either that can satisfy them push it to improve their performance. Aim of this study to find out how the effect of training and job characteristic on job performance of nurses and to know differences of the performance beetween before and after training at Langsa District General Hospital. The problems to be solved in this study is what the effect of training and job characteristics on job performance of the nurses and differences in job performance before and after training. This research used descriptive survey and the comparative method.The population in this study are all nurses who attended the training with minimal education DIIIof nursing or equivalent. The population is consist of 152 nurses and 63 are chosen to be the samples. The result of the first hypothesis of research show that training and job characteristics of task significance, autonomy and feedback simultaneously have significance affect 32,3% of job performance while the rest equal to 67.7% is not included in this research., partial test showed training variables, job characteristic of task significance, autonomy and feedback have significance effect on job performance and dominant variable is training. The results of second hipotesis showed the difference about the increase perfomance obtained by the nurse at Langsa General Hospital earlier from 81.43 to 81.93 with a correlation of 0.963. The resultsshows that there are significant differences that the nurses achievement before and after training.

This study was conducted to examine the effect of safety climate and personal experience on safety compliance, particularly in the use of personal protective equipment (PPE), of construction workers. Safety climate and compliance questionnaire was used to measure the level of safety climate and compliance. Personal experience variable consist of work experience and educational experience that was analyzed independently as two variables. The subject of this study (N=70) are construction workers in the rehabilitation project of Amongrogo, in Yogyakarta. Multiple regressions is used for data analyzing. The result indicate the significant effect of both safety climate and personal experience toward safety compliance, particularly in the use of PPE (R 2= .253; p

PENGARUH IODIUM DAN SELENIUM TERHADAP JUMLAH SEL SPERMATOGONIUM DAN STRUKTUR HISTOLOGIS TUBULUS SEMINIFERUS TESTIS TIKUS WISTAR HIPOTIROID Iodine and Selenium Effect on Spermatogonia Cell Numbers and Histologist Structure of Seminiferous Tubules Testis Hypothyroid Wistar Rats ABSTRACT Background. Thyroid hormones are proven to have a direct effect on sexual development and reproductive function. Hypothyroidism in men cause decreased libido, impotence, and oligospermie. Thyroid disorders associated with abnormal testicular morphology and function. Selenium was closely related to male fertility. Glutathione peroxidase 4 (GPx4) was first known as the antioxidant enzymes is selenoenzyme which is dominant in testis allegedly important for spermatogenesis. Objective. The aim of this study was to evaluate spermatogonia cell numbers and the histological structure of seminiferous tubules of hypothyroid rats as a result of the intervention with iodine and selenium. Method. An experimental study with post-test only control group design. Fifty hypothyroidism male Wistar rats induced by Propylthiouracil (PTU) for four week were divided into three groups through simple random sampling. Group I treated with iodine, group II treated with iodine + selenium and group III is control group. Sampling to determine groups by randomization. Blood sample was taken and then Thyroid Stimulating Hormone (TSH) blood level was measured using an Enzyme-Linked Immunosorbent Assay (ELISA). Whereas, spermatogonia cell numbers and the histological structure of seminiferous tubules was measured using Hematoxylin Eosin (HE) histologist. Anova test was used to compare the data obtained from treated and control groups of TSH blood level and spermatogonia cell numbers. Data of seminiferous tubules histological structure were analyzed by comparing between groups. Result. TSH blood level in group I (3.5 ± 4.9 μIU/mL), group II (1.9 ± 1.5 μIU/mL, and group III (13.5 ± 8.3 μIU/mL) was significantly difference with value (p=0.000). However, spermatogonia cell numbers on group I (66.6 ± 18.1), group II (57.4 ± 3.3), on group III (53.6 ± 5.3) was not significantly difference with value (p=0.204). Observation of the seminiferous tubules in group I and II showed that spermatogenic cell structure appeared more clearly, with more full spermatogenic structures, narrower tubular lumen contains lots of sperm. Observations in group III showed abnormal seminiferous tubules, irregular arrangement of spermatogenic cells with wider lumen contains few sperm. Conclusion. Iodine and selenium had no effect on the average number of spermatogonia cells and affected the histological structure of the seminiferous tubules in wistar rats testis. Keywords: hypothyroid, iodine, selenium, spermatogenesis, TSH ABSTRAK Latar Belakang. Hormon tiroid mempengaruhi perkembangan seksual dan fungsi reproduksi. Hipotiroid pada pria dapat menyebabkan libido berkurang, impotensi, dan oligospermia. Kelainan tiroid terkait dengan kelainan morfologi dan fungsi testis. Selenium erat kaitannya dengan kesuburan laki-laki. Glutathione peroksidase 4 (GPx4) pertama kali dikenal sebagai enzim antioksidan adalah selenoenzyme dominan di testis dan diduga penting dalam proses spermatogenesis. Tujuan. Tujuan dari penelitian ini adalah untuk mengkaji jumlah sel spermatogonium dan struktur histologis tubulus seminiferus tikus hipotiroid akibat intervensi iodium dan selenium. Metode. Penelitian ini menggunakan metode eksperimen dengan rancangan post-test only control group design. Subyek penelitian ini berjumlah 15 ekor tikus Wistar jantan yang sebelumnya dibuat hipotiroid dengan pemberian PTU dengan dosis 15 mg/kg BB. Tikus dibagi menjadi tiga kelompok, yaitu kelompok perlakuan I (intervensi iodium), II (iodium dan selenium) dan kelompok kontrol III (kontrol hipotiroid). Masing-masing kelompok terdiri dari lima ekor tikus yang ditentukan dengan cara randomisasi. Penentuan kadar TSH diambil dari serum darah untuk menentukan hipotiroid dan jumlah spermatogonium serta struktur histologis tubulus seminiferus diambil dari sediaan histologi testis. Kadar TSH dan jumlah spermatogonium dianalisis menggunakan uji Anova. Struktur histologis tubulus seminiferus testis dianalisis dengan cara membandingkan antara kelompok. Hasil. Kadar TSH pada kelompok I (3.5 ± 4.9 μIU/mL), kelompok II (1.9 ± 1.5 μIU/mL), dan kelompok III (13.5 ± 8.3 μIU/mL). Uji stastistik mendapatkan hasil beda nyata dengan nilai (p=0.000). Jumlah rata-rata sel spermatogonium pada kelompok I (66.6 ± 18.1), kelompok II (57.4 ± 3.3) dan pada kelompok III (53.6 ± 5.3). Uji stastistik mendapatkan hasil tidak beda nyata dengan nilai (p=0.204). Pengamatan tubulus seminiferus pada kelompok I dan II didapatkan susunan sel spermatogenik yang lebih jelas, dengan struktur spermatogenik yang lebih rapat, dan lumen tubulus yang lebih sempit dan terisi dengan sperma. Pada kelompok III tubulus seminiferus abnormal, susunan sel-sel spermatogenik tidak teratur dan kurang rapat. Lumen tampak lebar dan terisi sedikit sperma. Kesimpulan. Iodium dan selenium tidak berpengaruh pada jumlah rata-rata sel spermatogonium testis tikus tetapi berpengaruh terhadap struktur histologis tubulus seminiferus testis tikus. Kata kunci: hipotiroid, iodium, selenium, spermatogenesis, TSH

ABSTRACT Iodine Deficiency Disorders (IDD) was associated with female reproductive hormones disorders. Hypothyroidism inhibits follicular development which subsequently inhibited estrogen secretion. Biosynthesis of estrogen derived from testosterone through aromatization mechanism in ovarian granulose cells. This study aimed to determine changes in levels of serum testosterone and estrogen in hypothyroid rats induced by propylthiouracil. This study was an experimental post test only with controlled group design. Study used 11 Sprague dawley female rats aged 2.5 months with an average body weight 111.1 grams. Five rats given propylthiouracil in the drinking water with doses of 0.1 g/L for 30 days and six rats were used as controls. Hypothyroid rats were determined by measurements of free T4 levels. Data of free T4 levels, testosterone, and estrogen taken from blood serum and it were measured using ELISA technique. Data of testosterone, estrogen, and free T4 analysis using independent sample t test. Free T4 levels of treatment group were 4.0 ± 0.4 pmol/L and the controlled group were 8.1 ± 1.6 pmol/L, statistical analysis showed significant difference between the two groups with p values = 0.001. Testosterone levels of the treatment group were 0.72 ± 0.1 pg/dL and control group were 0.66 ± 0.1 pg/dL, statistical analysis showed no significant difference between the two groups with p values = 0.20. Estrogen levels of the treatment group were 9.4 ± 6.2 pg/dL and control group were 12.6 ± 3.9 pg/dL, statistical analysis showed no significant difference between the two groups with p values = 0.35. There was no significant change in the levels of testosterone and estrogen serum in Sprague dawley female hypothyroid rats induced by propylthiouracil. Keywords: hypothyroidism, testosterone, estrogen, free T4, Sprague dawley. ABSTRAK Gangguan Akibat Kekurangan Iodium (GAKI) ada hubungannya dengan hormon reproduksi perempuan. Hipotiroid menghambat perkembangan folikuler sehingga sekresi estrogen terhambat. Biosintesis hormon estrogen berasal dari hormon testosteron melalui mekanisme aromatisasi di dalam sel granulosa ovarium. Penelitian ini bertujuan mengetahui perubahan kadar hormon testosteron dan estrogen serum pada tikus hipotiroid dengan induksi propylthiouracil. Penelitian ini adalah studi eksperimental dengan rancangan post test only with controlled group, menggunakan 11 tikus jenis Sprague dawley betina berumur 2,5 bulan dengan berat badan rata-rata 111,1 gram. Lima ekor tikus sebagai perlakuan diberi propylthiouracil dalam air minum dengan kadar 0,1 g/L selama 30 hari dan enam ekor tikus digunakan sebagai kontrol. Untuk menentukan tikus hipotiroid digunakan pengukuran kadar T4 bebas. Data kadar T4 bebas, testosteron, dan estrogen diambil dari serum darah dan diukur dengan menggunakan teknik ELISA. Data kadar testosteron, estrogen, dan T4 bebas diuji dengan menggunakan uji statistik t tidak berpasangan. Kadar T4 bebas kelompok perlakuan (4,0 ± 0,4 pmol/L) dan kelompok kontrol (8,1 ± 1,6 pmol/L), uji statistik menunjukkan beda bermakna antara kedua kelompok dengan nilai p = 0,001. Kadar testosteron pada kelompok perlakuan (0,72 ± 0,1 pg/dL) dan kelompok kontrol (0,66 ± 0,1 pg/dL), uji statistik menunjukkan tidak beda bermakna antara kedua kelompok dengan nilai p = 0,20. Kadar estrogen pada kelompok perlakuan (9,1 ± 6,2 pg/dL) dan kelompok kontrol (12,6 ± 3,9 pg/dL), analisis statistik menunjukkan tidak beda bermakna antara kedua kelompok dengan nilai p = 0,35. Tidak terjadi perubahan signifikan kadar testosteron dan estrogen serum pada tikus Sprague dawley betina hipotiroid dengan induksi propylthiouracil. Kata kunci: hipotiroid, testosteron, estrogen, T4 bebas, Sprague dawley.

Parameter oseanografi seperti upwelling dan thermal front dapat digunakan sebagai indikator daerah penangkapan ikan potensial. Pengetahuan tentang lokasi perairan dengan fenomena tersebut akan dapat membantu para nelayan untuk mencari daerah penangkapan ikan potensial. Penelitian ini bertujuan untuk menentukan sebaran suhu permukaan laut (SPL), dan memprediksi keberadaan thermal front dan upwelling di perairan Mentawai. Penelitian ini dilaksanakan pada bulan Maret-Mei 2006 di Perairan Mentawai. Sedangkan Citra SPL yang diolah Juni 2006-September 2007.Analisa data yang digunakan adalah secara visual untuk menentukan thermal front dan upwelling. Pada musim timur SPL berkisar 26-32°C, musim peralihan timur-barat berkisar 23-32oC, musim barat berkisar 23-32oC, musim peralihan barat-timur berkisar antara 25-32oC. Thermal front hampir ditemukan sepanjang tahun di sekitar Pulau Siberut, Pulau Sipora, Pulau Pagai Utara, Pulau Pagai Selatan dan sekitar Pasaman. Indikasi upwelling tidak ditemukan pada musim barat. Pada musim timur, upwelling ditemukan di sekitar Pulau Siberut, Pulau Sipora, Pulau Pagai Utara, Pulau Pagai Selatan. Pada musim peralihan timur barat, upwelling ditemukan di sekitar Pulau Siberut, Pulau Sipora, Pulau Pagai Utara. Pada musim barat timur, upwelling ditemukan di sekitar Pulau Sipora, Pulau Pagai Utara. Kata kunci: Perairan Mentawai, suhu permukaan laut (SPL), thermal front, upwelling

Background: Iodine is the essential component for synthesis of tyroid. In the area of dificiency iodium the iodine intake was also obtained from high doses of iodine capsules and iodized salt. While in the area of non-iodine deficiency, iodine source may be more complex, considering a more varied diet and a lot of drugs containing iodine. The Wayne index used to estimate the suspect of hyperthyroidism but to get right diagnosis for hyperthyroidism are use laboratory examination. Positiv hyperthyroidsm if TSH in serum < 0,3 µlU/ml and FT4 > 2 nano gram/dl. Obyektives: The purpose of this paper is to view clinical characteristic in the nonendemik areas and endemic iodine deficiency disorder. Method: The method used is analitic research design with a crosssectional study. Respondent of the research are woman that age 15-50 years old. The number of samples in this research is 36 woman from endemic areas and 36 samples from non endemic areas. Analysis of data using excel and SPSS programs. Result: Results can be seen that in general clinical characteristics in two areas namely endemic and non endemic areas are not statistically different with p = 0.803 (p> 0.05). But in these two regions are typical symptoms of hyperthyroidism suspect in non-endemic area when compared with endemic areas such as the prominent and showed statistical differences in the symptoms exopthalmus value of p = 0.00, rapid pulse value p = 0.01, appetite increased with p-value = 0.03. alue index of sensitivity and specificity to predict hyperthyroid wayne in endemic areas is 0.67 and Se 0.87. While the value of sensitivity and specificity indices wayne to suspect hyperthyroidism in non-endemic areas is 0.55 and 0.925Se. Keywords: hyperthyroidism, endemic, non endemic, clinical characteristics

In tuna fisheries along south coast Java, rumpon (fish aggregating devices) are mostly used by fishermen. The using of this technology implies in increasing catch. Some result from previous researches indicated that tuna catch from trolling were small size and far from export quality standard. This phenomenon threats sustainability of tuna fisheries. The aim of this research was to determine feasibility of tuna catch and its quality that trolling around rumpon. This research was carried out in Tamperan fishing port within July-August 2010 and Sadeng fishing port within 15-29 July 2010. Survey method was used in this research and the catch data were analyzed based on their composition, size and organoleptic The result showed that in Tamperan fishing port most of the catch was yellow fin tuna, 68% was under size (below the length of maturity) and 75% organoleptic value was below 7. In Sadeng fishing port most of the catch was big eye, 95% was under size and organoleptic value was more than 7 for all catch. For exporting whole fresh tuna, the organoleptic value of more than 7 is needed. Keywords: tuna resources, sustainability, rumpon, South Coast of Java --------------- Rumpon banyak digunakan pada perikanan pancing tonda untuk menangkap tuna di perairan selatan Pulau Jawa. Penggunaan rumpon telah meningkatkan produksi tuna yang sangat tinggi di beberapa perairan. Dari beberapa hasil penelitian diinformasikan bahwa jenis ikan hasil tangkapan pancing tonda adalah tuna yang berukuran kecil dengan mutu yang tidak memenuhi standar ekspor. Penelitian ini bertujuan untuk menentukan kelayakan hasil tangkapan tuna di sekitar rumpon. Penelitian dilakukan di PPP Tamperan antara Juli-Agustus 2010 dan PPP Sadeng antara 15-29 Juli 2010. Metode penelitian yang digunakan adalah metode survei dimana analisis dilakukan terhadap komposisi jenis, ukuran hasil tangkapan dan organoleptik. Hasil penelitian menunjukkan bahwa jenis tuna hasil tangkapan dominan nelayan PPP Tamperan adalah jenis yellowfin. Sekitar 68% berukuran kecil dan belum layak tangkap. Jenis hasil tangkapan tuna di Sadeng didominasi oleh bigeye tuna. Hampir 95% dari seluruh tangkapannya berukuran kecil dan belum layak tangkap. Selanjutnya, 75% tuna hasil tangkapan nelayan PPP Tamperan memiliki nilai organoleptik kurang dari 7. Sementara nilai organoleptik tuna yang tertangkap nelayan PPP Sadeng lebih dari 7. Kata kunci: sumberdaya tuna, keberlanjutan, rumpon, pantai selatan

Background: The number of dysmenorrhea in Indonesia is 64,25%. About 54,98% had primary dysmenorrhea, and 9,36% had secondary dysmenorrhea. The continuity of abdominal muscle contraction causes the pain of dysmenorrhea during the menstrual period. A combination of gentle massage and linalool in aromatherapy will stimulate the hypothalamus to produce endorphin hormones to reduce the tension of the uterus’s muscle due to the menstrual. Objective: To know the effect of combining petrissage massage with Cananga aromatherapy for dysmenorrhea in teenage girls at senior high school. Methods: This research used Pre Experimental method with one group pretest-postest approach. The population for this study is 540 people. The sampling technique used a rule of thumb by the number of 30 people of teenage girls at the high school. A parametric test and paired t-test processed the data. Result: After giving intervention was available, 28 respondents (93%) with dysmenorrhea reduced, and 2 respondents (7%) remained dysmenorrhea. The analysis result was obtained with a p = 0,000 (p

This literature study intends to dissect the literature on how the effect of good corporate governance mechanism on financial distress in a company. In CG Asian Watch 2020, Indonesia is ranked last among the 12 countries in Asia. In CG Asian Watch 2020, Indonesia is ranked last among the 12 countries in Asia. This shows that good corporate governance in Indonesia is still relatively weak, so it is interesting to study further. The method used in this research is qualitative research with a literature study technique using 18 articles. Good corporate governance variables in this literature study involve managerial ownership; independent commissioners; audit committees; institutional ownership; the board of directors; and firm size. This article attempts to describe the results of previous research on the role of good corporate governance to prevent financial distress. The results of the study indicate that there is an influence of good corporate governance on the company's financial distress, both positive and negative. Keywords: corporate governance; good corporate governance, financial distress ABSTRAK Studi literatur ini mempunyai tujuan untuk untuk membedah literatur tentang pengaruh dari GCG (Good Corporate Governance) terhadap financial distress pada perusahaan. Dalam CG Asian Watch 2020, Indonesia berada pada peringkat paling akhir diantara 12 negara di Asia. Berdasarkan hal tersebut dapat diketahui bahwa penerapann GCG di Indonesia masih tergolong lemah sehingga menarik untuk dikaji lebih dalam. Peneliti menggunakan pendekatan kualitatif dengan metode studi literatur yang sumber dari 18 artikel. Variabel GCG dalam penelitian ini terdiri dari komisaris independent, kepemilikan manajerial, komite audit, kepemilikan institusional, dewan direksi dan ukuran perusahaan. Artikel ini berusaha untuk menggambarkan hasil-hasil penelitian terdahulu mengenai peran good corporate governance sebagai upaya untuk mencegah terjadinya permasalahan kesulitan keuangan IFinacial Distress). Hasil penelitian yang dilakukan oleh peneliti menunjukan bahwa bahwa terdapat pengaruh good corporate governance terhadap financial distress perusahaan baik secara positif maupun negatif. Kata Kunci: tata kelola perusahaan, tata kelola perusahaan yang baik, kesulitan keuangan

Abstrak. Salah satu kawasan sentra budidaya ikan yang ada di Kabupaten Banyumas, adalah Desa Jipang Kecamatan Karanglewas. Kawasan ini merupakan daerah potensial untuk dilakukan budidaya diakrenakan ketersediaan air sebagai media utama kegiatan budidaya ikan yang sangat mutlak dibutuhkan. Salah satu kelompok budidaya ikan adalah kelompok Lele Gaul dengan luas lahan budiaya Lele Gaul 720 m2. Tujuan kegiatan ini adalah peningkatan kompetensi pembuatan pakan ikan serta dapat meningkatkan produksi penjualan ikan. Metode pendekatan yang dilakukan dalam kegiatan ini adalah pendekatan partisipatif (PRA/Participatory Rural Appraisal) dengan cara sosialisasi dan penyuluhan tentang teknologi pembuatan pakan ikan, pelatihan dan bimbingan teknis secara langsung tentang pembuatan formulasi pakan dan melakukan perhitungan hasil produksi budidaya ikan selama 1 siklus. Hasil dari pengabdian ini adalah mitra mengetahui teknologi pembuatan pakan dengan menggunakan bahan-bahan yang tersedia dan melimpah sehingga dapat mengurangi pengeluaran produksi dalam budidaya ikan.

Co-administered medicinal herbs can modify a drug's pharmacokinetics (PK), effectiveness, and toxicity. Andrographis paniculata (Burm. f.) ethanolic extract (APE) and andrographolide (AND) (a potent CYP2C9 inducer/inhibitor) can alter the pharmacokinetic parameters of glipizide (GLZ). This study aimed to determine the potential pharmacokinetics of herb–drug interactions between GLZ and APE/AND in the plasma of normal and diabetic rats using the HPLC bioanalysis method. The glipizide bioanalytical method established with RP-HPLC/UV instrument was validated following the EMA guidelines. GLZ was administered alone and in combination with APE or AND to normal and diabetic rats. The GLZ pharmacokinetic parameters were estimated according to the correlation between concentration and sampling time using the PK solver program. A simple and rapid GLZ bioanalysis technique with a lower limit of quantitation of 25 ng/mL was developed and presented the following parameters: accuracy (error ≤ 15%), precision (CV ≤ 15%), selectivity, stability, and linearity (R2 = 0.998) at concentrations ranging 25–1500 ng/mL. APE administration significantly improved the Cmax and AUC0–t/AUC0–∞ GLZ values in normal and diabetic rats (p < 0.05). AND significantly reduced the bioavailability of GLZ in diabetic rats with small values of T 1/2, Cmax, and AUC0–t/AUC0–∞ (p < 0.05). This combination can be considered in administering medications because it can influence the pharmacological effects of GLZ. [ABSTRACT FROM AUTHOR]

TRANSFER OF ARTEMIA SP HATCHING TECHNOLOGY FOR FISH LARVA FEED IN KARYA MULYA 2 FISH CULTIVATION GROUP, PASIR LOR VILLAGE, BANYUMAS REGENCY. This community service aims to improve skills and knowledge about hatching Artemia sp as fish larvae feed through technology transfer to the Karya Mulya 2 fish cultivation group. The method used is “Participatory Rural Appraisal” which is to increase community participation and increase community involvement which is carried out through counseling, direct demonstrations and technical guidance. Technical guidance training activities include the preparation of tools in the form of aerators, aerator hoses, buckets and mixing spoons. Preparation of materials in the form of water, salt and cysts of Artemia sp. Followed by the practice of incubating Artemia sp and Harvesting Artemia sp. The results of this community service can improve the skills and knowledge of the Karya Mulya 2 fish farming group to apply simple Artemia sp hatching technology as feed to increase the growth of fish larvae.

The development of this conceptual model is directed to encourage consumer purchases of products where this process occurs by online. The research model developed is called a synergy factor which includes system factors, internal factors, external factors and product factors. Each of these factors has characteristics in the form of variables consisting of website aesthetics from system factors, availability of money from internal factors, word of mouth from external factors and price perception of product factors. These four elements will determine the interest that will ultimately drive the purchase. The process in this research model is not in purchases that generally occur but in impulsive purchases or purchases without planning.

Co-administered medicinal herbs can modify a drug’s pharmacokinetics (PK), effectiveness, and toxicity. Andrographis paniculata (Burm. f.) ethanolic extract (APE) and andrographolide (AND) (a potent CYP2C9 inducer/inhibitor) can alter the pharmacokinetic parameters of glipizide (GLZ). This study aimed to determine the potential pharmacokinetics of herb–drug interactions between GLZ and APE/AND in the plasma of normal and diabetic rats using the HPLC bioanalysis method. The glipizide bioanalytical method established with RP-HPLC/UV instrument was validated following the EMA guidelines. GLZ was administered alone and in combination with APE or AND to normal and diabetic rats. The GLZ pharmacokinetic parameters were estimated according to the correlation between concentration and sampling time using the PK solver program. A simple and rapid GLZ bioanalysis technique with a lower limit of quantitation of 25 ng/mL was developed and presented the following parameters: accuracy (error ≤ 15%), precision (CV ≤ 15%), selectivity, stability, and linearity (R2 = 0.998) at concentrations ranging 25–1500 ng/mL. APE administration significantly improved the Cmax and AUC0–t/AUC0–∞ GLZ values in normal and diabetic rats (p < 0.05). AND significantly reduced the bioavailability of GLZ in diabetic rats with small values of T 1/2, Cmax, and AUC0–t/AUC0–∞ (p < 0.05). This combination can be considered in administering medications because it can influence the pharmacological effects of GLZ.

Data menunjukkan bahwa dari tahun ke tahun Indeks Persepsi Korupsi Indonesia terus meningkat. Hal ini menunjukkan bahwa komitmen pemerintah yang direalisasikan melalui berbagai upaya dalam menangani masalah korupsi telah berada di jalur yang tepat walaupun belum optimal. Korupsi masih menjadi masalah yang serius di Indonesia karena masih dapat dilakukan oleh siapa saja, terjadi di berbagai tempat, dan dalam berbagai jenis perkara dengan jumlah yang cenderung meningkat dari tahun ke tahun. Undang-undang Nomor 30 Tahun 2002 Pasal 13 menyebutkan bahwa salah satu upaya pencegahan yang dapat dilaksanakan oleh KPK adalah menyelenggarakan program pendidikan antikorupsi pada setiap jenjang pendidikan. Hal ini menunjukkan bahwa dunia pendidikan penting dilibatkan dalam upaya pemberantasan korupsi. Penelitian ini bertujuan untuk mengembangkan media pembelajaran Pendidikan Antikorupsi berbasis multimedia untuk tingkat perguruan tinggi yang disebut MedPAK. MedPAK dikembangkan dengan mengadopsi metode Research and Development. Hasil penilaian materi pada MedPAK menunjukkan rata-rata persentase 88% sedangkan hasil penilaian media adalah sebesar 84% di mana keduanya termasuk kategori baik. Dapat disimpulkan bahwa MedPAK layak untuk digunakan.

ABSTRACT This study entitled “Peningkatan Hasil Belajar IPS Melalui Metode Two Stay Two Stray pada Siswa Kelas V SDN Cempaka Baru 01 Jakarta Pusat”. The subject of this research is the grade V. This study departs from the background of the results of the study subjects are still low, IPS under KKM. So author moved to find the cause and try to improve the learning outcomes through learning methods two stay two stray (tsts). As for the purpose of this research is to improve the learning outcomes of students of class V SDN Cempaka Baru 01 on social science subjects.The method used is the class action Research with two cycles of hypothesis method with two stay two stray can improve the learning results of IPS on grade V in SDN Cempaka Baru 01. The results showed that the method can improve the learning results of tsts cognitive, affective and psychomotor the students in social science subjects. The results of the student learning experience an increase in classical and individually. This is due to the use of cooperative learning model of type two stay two stray has involved students learn actively and enhance their understanding of the material being taught. In Cycle I, students who complete of 44.83%, cycle II of 93.10%. While in the realm of affective in cycle I are classical space being in the category is good enough and in cycle II are in the category either. And in the realm of psychomotor, in classical average cycle I showed enough skilled category and on cycle II shows the category of skilled. Keywords: two stay two stray, the results of the study, IPS.

Komputer yang berguna untuk pengolahan data yang rumit di berbagai bidang, dan juga untuk sistem informasi geografis wisata kuliner yang di web di pekanbaru. Agar menjadi lebih efektif dan efisien. Data dan informasi yang sangat berharga bagi suatu organisasi atau perusahaan. Tidak ada sistem pengolahan data dan informasi geografis wisata kuliner di pekanbaru, hal itu menyebabkan orang tidak bisa mengenali wisata kuliner yang ada di Pekanbaru. Sistem informasi geografis wisata kuliner dengan menggunakan aplikasi yang dibuat bahasa pemrograman web berbasis berbasis PHP diharapkan untuk menyediakan fasilitas untuk mengenali wisata kuliner yang ada di Pekanbaru. Hal ini dapat disimpulkan bahwa aplikasi dapat membantu orang terutama orang - orang yang tinggal di Pekanbaru tahu lebih banyak tentang wisata kuliner di Pekanbaru

Tujuan dari penelitian ini adalah untuk menganalisa hubungan langsung antara iklim organisasi dan kompensasi terhadap komitmen organisasi serta menganalisa hubungan tidak langsung antara iklim organisasi dan kompensasi dengan menggunakan karir sebagai variabel antara dengan Komitmen Organisasi. Objek penelitian ini adalah Perusahaan Telekomunikasi Indonesia, dan responden penelitian ini adalah seluruh karyawan di Departemen Teknis. Total populasi di Departemen Teknis adalah 66 karyawan, dengan menggunakan teknik sampel jenuh atau sensus, dimana semua karyawan adalah responden dalam penelitian ini. Teknik analisis dengan menggunakan analisis jalur yang akan menghitung parameter antara hubungan langsung dan tidak langsung. Hasil pertama dari penelitian ini adalah iklim organisasi memiliki hubungan positif langsung yang signifikan terhadap komitmen organisasi sementara kompensasi memiliki hubungan langsung negatif dan tidak signifikan terhadap komitmen organisasi. Hasil kedua penelitian ini adalah iklim organisasi dan kompensasi memiliki hubungan tidak langsung positif dan tidak signifikan terhadap komitmen organisasi melalui karir. Fenomena ini dapat dijelaskan bahwa karyawan di Departemen Teknis adalah sumber daya manusia yang langka di perusahaan telekomunikasi di Indonesia keterampilan mereka dibutuhkan oleh perusahaan.