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2,618 results on '"Morrow, Monica"'

404. The Impact of Surgeon Referral and a Radiation Oncologist Productivity-Based Metric on Radiotherapy Receipt Among Elderly Women with Early-Stage Breast Cancer: Analysis from a Tertiary Cancer Network

Author

Patel, Mira A, primary, Cha, Elaine E., additional, Lobaugh, Stephanie, additional, Zhang, Zhigang, additional, McCormick, Beryl, additional, Braunstein, Lior Z., additional, Cahlon, Oren, additional, Powell, Simon N., additional, Morrow, Monica, additional, Khan, Atif, additional, and Gillespie, Erin F., additional

Published
2021
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410. Breast Conservation Among Older, Early-Stage Breast Cancer Patients: Locoregional Recurrence Following Adjuvant Radiation or Hormonal Therapy

Author

Tringale, Kathryn R, Berger, Elizabeth R, Sevilimedu, Varadan, Wen, Hannah Y., Gillespie, Erin F, Mueller, Boris A., McCormick, Beryl, Xu, Amy J, Cuaron, John J, Cahlon, Oren, Khan, Atif J., Powell, Simon N., Morrow, Monica, Heerdt, Alexandra S., and Braunstein, Lior Z.

Subjects
Article
Abstract

BACKGROUND: Among breast cancer patients undergoing breast-conserving surgery (BCS), adjuvant radiation (RT) and hormonal therapy (HT) reduce the risk of locoregional recurrence (LRR). While several studies have evaluated adjuvant HT+/−RT, the outcomes of HT versus RT monotherapy remain less clear. We characterize the risk of LRR among older, early-stage breast cancer patients following adjuvant RT alone, HT alone, neither, or both. METHODS: This study included patients from our institution age ≥65 years with estrogen receptor positive (ER+)/HER2− T1N0 BC treated with BCS. The primary endpoint was time to LRR evaluated by Cox regression analysis. RESULTS: We evaluated 888 women with a median age of 71 years (range 65-100) and median follow-up of 4.9 years (range 0.0-9.5). There were 27 (3.0%) LRR events: 5-year LRR was 11% for those receiving no adjuvant treatment, 3% for HT alone, 4% for RT alone, and 1% for HT and RT. LRR rates were significantly different between the groups (p

Published
2021

411. Tumor-Nipple Distance of ≥ 1 cm Predicts Negative Nipple Pathology After Neoadjuvant Chemotherapy.

Author

Moo, Tracy-Ann, Moo, Tracy-Ann, Saccarelli, Carolina, Sutton, Elizabeth, Sevilimedu, Varadan, Pawloski, Kate, DAlfonso, Timothy, Hughes, Mary, Gluskin, Jill, Bitencourt, Almir, Tadros, Audree, Morrow, Monica, Gemignani, Mary, Sacchini, Virgilio, Morris, Elizabeth, Moo, Tracy-Ann, Moo, Tracy-Ann, Saccarelli, Carolina, Sutton, Elizabeth, Sevilimedu, Varadan, Pawloski, Kate, DAlfonso, Timothy, Hughes, Mary, Gluskin, Jill, Bitencourt, Almir, Tadros, Audree, Morrow, Monica, Gemignani, Mary, Sacchini, Virgilio, and Morris, Elizabeth

Abstract

BACKGROUND: As neoadjuvant chemotherapy (NAC) for breast cancer has become more widely used, so has nipple-sparing mastectomy. A common criterion for eligibility is a 1 cm tumor-to-nipple distance (TND), but its suitability after NAC is unclear. In this study, we examined factors predictive of negative nipple pathologic status (NS-) in women undergoing total mastectomy after NAC. METHODS: Women with invasive breast cancer treated with NAC and total mastectomy from August 2014 to April 2018 at our institution were retrospectively identified. Following review of pre- and post-NAC magnetic resonance imaging (MRI) and mammograms, the association of clinicopathologic and imaging variables with NS- was examined and the accuracy of 1 cm TND on imaging for predicting NS- was determined. RESULTS: Among 175 women undergoing 179 mastectomies, 74% of tumors were cT1-T2 and 67% were cN+ on pre-NAC staging; 10% (18/179) had invasive or in situ carcinoma in the nipple on final pathology. On multivariable analysis, after adjusting for age, grade, and tumor stage, three factors, namely number of positive nodes, pre-NAC nipple-areolar complex retraction, and decreasing TND, were significant predictors of nipple involvement (p < 0.05). The likelihood of NS- was higher with increasing TND on pre- and post-NAC imaging (p < 0.05). TND ≥ 1 cm predicted NS- in 97% and 95% of breasts on pre- and post-NAC imaging, respectively. CONCLUSIONS: Increasing TND was associated with a higher likelihood of NS-. A TND ≥ 1 cm on pre- or post-NAC imaging is highly predictive of NS- and could be used to determine eligibility for nipple-sparing mastectomy after NAC.

Published
2021

412. Customizing local and systemic therapies for women with early breast cancer:the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021

Author

Burstein, H. J., Curigliano, Giuseppe, Thürlimann, B., Weber, W. P., Poortmans, Philip, Regan, Meredith, Senn, H. J., Winer, E. P., Gnant, M., Aebi, Stephan, André, Fabrice, Barrios, Carlos, Bergh, Jonas, Bonnefoi, Herve, Bretel Morales, Denisse, Brucker, Sara, Burstein, Harold, Cameron, David, Cardoso, Fatima, Carey, Lisa, Chua, Boon, Ciruelos, Eva, Colleoni, Marco, Delaloge, Suzette, Denkert, Carsten, Dubsky, Peter, Ejlertsen, Bent, Fitzal, Florian, Francis, Prudence, Galimberti, Viviana, Gamal El Din Mohamed Mahmoud, Hebatallah, Garber, Judy, Gnant, Michael, Gradishar, William, Gulluoglu, Bahadir, Harbeck, Nadia, Huang, Chiun Sheng, Huober, Jens, Ilbawi, Andre, Jiang, Zefei, Johnston, Steven, Lee, Eun Sook, Loibl, Sibylle, Morrow, Monica, Partridge, Ann, Piccart, Martine, Prat, Aleix, Burstein, H. J., Curigliano, Giuseppe, Thürlimann, B., Weber, W. P., Poortmans, Philip, Regan, Meredith, Senn, H. J., Winer, E. P., Gnant, M., Aebi, Stephan, André, Fabrice, Barrios, Carlos, Bergh, Jonas, Bonnefoi, Herve, Bretel Morales, Denisse, Brucker, Sara, Burstein, Harold, Cameron, David, Cardoso, Fatima, Carey, Lisa, Chua, Boon, Ciruelos, Eva, Colleoni, Marco, Delaloge, Suzette, Denkert, Carsten, Dubsky, Peter, Ejlertsen, Bent, Fitzal, Florian, Francis, Prudence, Galimberti, Viviana, Gamal El Din Mohamed Mahmoud, Hebatallah, Garber, Judy, Gnant, Michael, Gradishar, William, Gulluoglu, Bahadir, Harbeck, Nadia, Huang, Chiun Sheng, Huober, Jens, Ilbawi, Andre, Jiang, Zefei, Johnston, Steven, Lee, Eun Sook, Loibl, Sibylle, Morrow, Monica, Partridge, Ann, Piccart, Martine, and Prat, Aleix

Abstract

The 17th St Gallen International Breast Cancer Consensus Conference in 2021 was held virtually, owing to the global COVID-19 pandemic. More than 3300 participants took part in this important bi-annual critical review of the ‘state of the art’ in the multidisciplinary care of early-stage breast cancer. Seventy-four expert panelists (see Appendix 1) from all continents discussed and commented on the previously elaborated consensus questions, as well as many key questions on early breast cancer diagnosis and treatment asked by the audience. The theme of this year's conference was ‘Customizing local and systemic therapies.’ A well-organized program of pre-recorded symposia, live panel discussions and real-time panel voting results drew a worldwide audience of thousands, reflecting the far-reaching impact of breast cancer on every continent. The interactive technology platform allowed, for the first time, audience members to ask direct questions to panelists, and to weigh in with their own vote on several key panel questions. A hallmark of this meeting was to focus on customized recommendations for treatment of early-stage breast cancer. There is increasing recognition that the care of a breast cancer patient depends on highly individualized clinical features, including the stage at presentation, the biological subset of breast cancer, the genetic factors that may underlie breast cancer risk, the genomic signatures that inform treatment recommendations, the extent of response before surgery in patients who receive neoadjuvant therapy, and patient preferences. This customized approach to treatment requires integration of clinical care between patients and radiology, pathology, genetics, and surgical, medical and radiation oncology providers. It also requires a dynamic response from clinicians as they encounter accumulating clinical information at the time of diagnosis and then serially with each step in the treatment plan and follow-up, reflecting patient experiences a

Published
2021

435. Surgeon recommendations and receipt of mastectomy for treatment of breast cancer

Author

Morrow, Monica, Jagsi, Rsshma, Alderman, Amy K., Griggs, Jennifer J., Hawley, Sarah T., Hamilton, Ann S., Graff, John J., and Katz, Steven J.

Subjects
Mastectomy -- Patient outcomes, Lumpectomy -- Patient outcomes, Lumpectomy -- Comparative analysis, Breast cancer -- Care and treatment, Surgeons -- Beliefs, opinions and attitudes, Surgeons -- Practice
Abstract

A study was conducted to evaluate the surgeon recommendations for mastectomy surgery for women with breast cancer and compare them with second opinion recommendations. Results indicated that breast-conserving surgery (BCS) was recommended in most cases by surgeons and failure of BCS and patient decision all contributed to the increased rate of mastectomy.

Published
2009

447. Tumor-Nipple Distance of ≥ 1 cm Predicts Negative Nipple Pathology After Neoadjuvant Chemotherapy

Author

Moo, Tracy-Ann, primary, Saccarelli, Carolina Rossi, additional, Sutton, Elizabeth J., additional, Sevilimedu, Varadan, additional, Pawloski, Kate R., additional, D’Alfonso, Timothy M., additional, Hughes, Mary C., additional, Gluskin, Jill S., additional, Bitencourt, Almir, additional, Morris, Elizabeth A., additional, Tadros, Audree, additional, Morrow, Monica, additional, Gemignani, Mary L., additional, and Sacchini, Virgilio, additional

Published
2021
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450. Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer

Author

Freedman, Rachel A., primary, Minami, Christina A., additional, Winer, Eric P., additional, Morrow, Monica, additional, Smith, Alexander K., additional, Walter, Louise C., additional, Sedrak, Mina S., additional, Gagnon, Haley, additional, Perilla-Glen, Adriana, additional, Wildiers, Hans, additional, Wildes, Tanya M., additional, Lichtman, Stuart M., additional, Loh, Kah Poh, additional, Brain, Etienne G. C., additional, Ganschow, Pamela S., additional, Hunt, Kelly K., additional, Mayer, Deborah K., additional, Ruddy, Kathryn J., additional, Jagsi, Reshma, additional, Lin, Nancy U., additional, Canin, Beverly, additional, LeStage, Barbara K., additional, Revette, Anna C., additional, Schonberg, Mara A., additional, and Keating, Nancy L., additional

Published
2021
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