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Intravascular ultrasonic (IVUS) imaging catheters currently use ceramic piezoelectric transducers to form radial images of blood vessel walls. Further improvements in image quality may be enabled through Capacitive and Piezoelectric Micromachined Ultrasonic Transducers (CMUTs and PMUTs). Polymer PMUTs offer many benefits in imaging quality, however, the low acoustic sensitivity and high electrical impedance of polymer PMUTs prevents unbuffered use with 50-Ω IVUS cables. Here, we present the design and optimization of an integrated CMOS front-end specifically designed to be integrated on a 0.8-mm imaging catheter. A series-duplexer topology with active limiter was selected for simplicity of integration, and compatibility with conventional high-voltage IVUS pulser-receiver systems. Noise optimization of the front-end revealed that an impedance-matching optimum exists, which balances the system parasitic capacitances relative to the transducer complex impedance. Optimized design equations compared favorably to simulation results in predicting front-end bandwidth and transducer-referred SNR. Large-signal transient simulation showed that the front-end can withstand 100-V pulses while recovering in 240 ns for echo reception. The integrated front-end occupied 0.74 × 1.8 mm die area (including large solder-bump bond pads), with an estimated transducer-referred noise floor of 6.5 n V R M S / H z over a 100-MHz imaging bandwidth.

Crude oils, which are complex mixtures of hydrocarbons, can be characterized by nuclear magnetic resonance diffusion and relaxation methods to yield physical properties and chemical compositions. In particular, the field dependence, or dispersion, of T1 relaxation can be used to investigate the presence and dynamics of asphaltenes, the large molecules primarily responsible for the high viscosity in heavy crudes. However, the T2 relaxation dispersion of crude oils, which provides additional insight when measured alongside T1, has yet to be investigated systematically. Here we present the field dependence of T1-T2 correlations of several crude oils with disparate densities. While asphaltene and resin-containing crude oils exhibit significant T1 dispersion, minimal T2 dispersion is seen in all oils. This contrasting behavior between T1 and T2 cannot result from random molecular motions, and thus, we attribute our dispersion results to highly correlated molecular dynamics in asphaltene-containing crude oils., (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)