251. Advances in chitosan-based wound dressings: Modifications, fabrications, applications and prospects.
- Author
-
Ji, Maocheng, Li, Jianyong, Wang, Yi, Li, Fangyi, Man, Jia, Li, Jianfeng, Zhang, Chuanwei, Peng, Sixian, and Wang, Shiqing
- Subjects
- *
WOUND care , *CHITOSAN , *HYDROXYL group , *AMINO group , *WOUNDS & injuries , *MEDICAL research - Abstract
In the field of medical research, the development of safe and effective wound dressings is a continuous goal. Chitosan (CS) is highly sought after because of its unique biocompatibility, biodegradability, antibacterial, and healing-promoting properties. The CS molecule has a significant number of active amino and hydroxyl groups; thus, making substitutions and creating derivatives with varied biochemical properties are relatively straightforward processes. This review addresses the range of functions performed by CS and its derivatives in wound care, such as haemostasis, antibacterial, antioxidant, and wound healing. Furthermore, it summarises the various types of CS-based dressings, their performance features and applications. Finally, the future directions of CS-based dressings are proposed. [Display omitted] [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF