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1,055 results on '"Shin, Hyoung Doo"'

351. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Author

Gudbjartsson, Daniel F, primary, Bjornsdottir, Unnur S, additional, Halapi, Eva, additional, Helgadottir, Anna, additional, Sulem, Patrick, additional, Jonsdottir, Gudrun M, additional, Thorleifsson, Gudmar, additional, Helgadottir, Hafdis, additional, Steinthorsdottir, Valgerdur, additional, Stefansson, Hreinn, additional, Williams, Carolyn, additional, Hui, Jennie, additional, Beilby, John, additional, Warrington, Nicole M, additional, James, Alan, additional, Palmer, Lyle J, additional, Koppelman, Gerard H, additional, Heinzmann, Andrea, additional, Krueger, Marcus, additional, Boezen, H Marike, additional, Wheatley, Amanda, additional, Altmuller, Janine, additional, Shin, Hyoung Doo, additional, Uh, Soo-Taek, additional, Cheong, Hyun Sub, additional, Jonsdottir, Brynja, additional, Gislason, David, additional, Park, Choon-Sik, additional, Rasmussen, Linda M, additional, Porsbjerg, Celeste, additional, Hansen, Jakob W, additional, Backer, Vibeke, additional, Werge, Thomas, additional, Janson, Christer, additional, Jönsson, Ulla-Britt, additional, Ng, Maggie C Y, additional, Chan, Juliana, additional, So, Wing Yee, additional, Ma, Ronald, additional, Shah, Svati H, additional, Granger, Christopher B, additional, Quyyumi, Arshed A, additional, Levey, Allan I, additional, Vaccarino, Viola, additional, Reilly, Muredach P, additional, Rader, Daniel J, additional, Williams, Michael J A, additional, van Rij, Andre M, additional, Jones, Gregory T, additional, Trabetti, Elisabetta, additional, Malerba, Giovanni, additional, Pignatti, Pier Franco, additional, Boner, Attilio, additional, Pescollderungg, Lydia, additional, Girelli, Domenico, additional, Olivieri, Oliviero, additional, Martinelli, Nicola, additional, Ludviksson, Bjorn R, additional, Ludviksdottir, Dora, additional, Eyjolfsson, Gudmundur I, additional, Arnar, David, additional, Thorgeirsson, Gudmundur, additional, Deichmann, Klaus, additional, Thompson, Philip J, additional, Wjst, Matthias, additional, Hall, Ian P, additional, Postma, Dirkje S, additional, Gislason, Thorarinn, additional, Gulcher, Jeffrey, additional, Kong, Augustine, additional, Jonsdottir, Ingileif, additional, Thorsteinsdottir, Unnur, additional, and Stefansson, Kari, additional

Published
2009
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355. Association Analysis of Peroxisome Proliferator-activated Receptors Gamma Gene Polymorphisms with asprin hypersensitivity in Asthmatics

Author

Oh, Sun-Hee, primary, Park, Se-Min, additional, Park, Jong-Sook, additional, Jang, An-Soo, additional, Lee, Yong-Mok, additional, Uh, Soo-Taek, additional, Kim, Young Hoon, additional, Choi, In-Seon, additional, Kim, Mi-Kyeong, additional, Park, Byeong Lae, additional, Shin, Hyoung-Doo, additional, and Park, Choon-Sik, additional

Published
2009
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358. Genetic variants in the HLA-G region are associated with Kawasaki disease

Author

Kim, Jae-Jung, primary, Hong, Soo-Jong, additional, Hong, Young Mi, additional, Kim, Sun, additional, Kang, Mi-Jin, additional, Kim, Kwi-Joo, additional, Seo, Eul-Joo, additional, Yoo, Han-Wook, additional, Cheong, Hyun-Sub, additional, Shin, Hyoung-Doo, additional, Park, In-Sook, additional, and Lee, Jong-Keuk, additional

Published
2008
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364. Protein Tyrosine Phosphatase N1 Gene Variants Associated with Type 2 Diabetes Mellitus and Its Related Phenotypes in the Korean Population

Author

Hong, Kyung-Won, primary, Jin, Hyun-Seok, additional, Lim, Ji-Eun, additional, Ryu, Ha-Jung, additional, Ahn, Youn-Jhin, additional, Lee, Jong-Young, additional, Han, Bok-Ghee, additional, Shin, Hyoung-Doo, additional, Cho, Nam-Han, additional, Shin, Chol, additional, Woo, Jeong-Taek, additional, Park, Hun-Kuk, additional, and Oh, Berm-Seok, additional

Published
2008
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366. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

Author

Yasuda, Kazuki, primary, Miyake, Kazuaki, additional, Horikawa, Yukio, additional, Hara, Kazuo, additional, Osawa, Haruhiko, additional, Furuta, Hiroto, additional, Hirota, Yushi, additional, Mori, Hiroyuki, additional, Jonsson, Anna, additional, Sato, Yoshifumi, additional, Yamagata, Kazuya, additional, Hinokio, Yoshinori, additional, Wang, He-Yao, additional, Tanahashi, Toshihito, additional, Nakamura, Naoto, additional, Oka, Yoshitomo, additional, Iwasaki, Naoko, additional, Iwamoto, Yasuhiko, additional, Yamada, Yuichiro, additional, Seino, Yutaka, additional, Maegawa, Hiroshi, additional, Kashiwagi, Atsunori, additional, Takeda, Jun, additional, Maeda, Eiichi, additional, Shin, Hyoung Doo, additional, Cho, Young Min, additional, Park, Kyong Soo, additional, Lee, Hong Kyu, additional, Ng, Maggie C Y, additional, Ma, Ronald C W, additional, So, Wing-Yee, additional, Chan, Juliana C N, additional, Lyssenko, Valeriya, additional, Tuomi, Tiinamaija, additional, Nilsson, Peter, additional, Groop, Leif, additional, Kamatani, Naoyuki, additional, Sekine, Akihiro, additional, Nakamura, Yusuke, additional, Yamamoto, Ken, additional, Yoshida, Teruhiko, additional, Tokunaga, Katsushi, additional, Itakura, Mitsuo, additional, Makino, Hideichi, additional, Nanjo, Kishio, additional, Kadowaki, Takashi, additional, and Kasuga, Masato, additional

Published
2008
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367. Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians

Author

Ng, Maggie C.Y., primary, Park, Kyong Soo, additional, Oh, Bermseok, additional, Tam, Claudia H.T., additional, Cho, Young Min, additional, Shin, Hyoung Doo, additional, Lam, Vincent K.L., additional, Ma, Ronald C.W., additional, So, Wing Yee, additional, Cho, Yoon Shin, additional, Kim, Hyung-Lae, additional, Lee, Hong Kyu, additional, Chan, Juliana C.N., additional, and Cho, Nam H., additional

Published
2008
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373. Generation of Cloned Transgenic Cats Expressing Red Fluorescence Protein1

Author

Yin, Xi Jun, primary, Lee, Hyo Sang, additional, Yu, Xian Feng, additional, Choi, Eugene, additional, Koo, Bon Chul, additional, Kwon, Mo Sun, additional, Lee, Young S., additional, Cho, Su Jin, additional, Jin, Guang Zhen, additional, Kim, Lyoung Hyo, additional, Shin, Hyoung Doo, additional, Kim, Teoan, additional, Kim, Nam Hyung, additional, and Kong, Il Keun, additional

Published
2008
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375. Identification of genetic polymorphisms in FABP3 and FABP4 and putative association with back fat thickness in Korean native cattle

Author

Cho, Seo-Ae, primary, Park, Tae-Sung, additional, Yoon, Du-Hak, additional, Cheong, Hyun-Sub, additional, Namgoong, Sohg, additional, Park, Byung-Lae, additional, Lee, Hye-Won, additional, Han, Chang-Soo, additional, Kim, Eun-Mi, additional, Cheong, Il-Cheong, additional, Kim, Hee-Bal, additional, and Shin, Hyoung-Doo, additional

Published
2008
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376. Association of lipoprotein lipase (LPL) single nucleotide polymorphisms with type 2 diabetes mellitus

Author

Cho, Yoon Shin, primary, Go, Min Jin, additional, Han, Hye Ree, additional, Cha, Seung-Hun, additional, Kim, Hung-Tae, additional, Min, Haesook, additional, Shin, Hyoung Doo, additional, Park, Chan, additional, Han, Bok-Ghee, additional, Cho, Nam Han, additional, Shin, Chol, additional, Kimm, Kuchan, additional, and Oh, Bermseok, additional

Published
2008
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379. Polymorphisms and haplotypes of integrinα1 (ITGA1) are associated with bone mineral density and fracture risk in postmenopausal Koreans

Author

Lee, Hye-Ja, primary, Kim, Shin-Yoon, additional, Koh, Jung-Min, additional, Bok, Jung, additional, Kim, Kwang-Joong, additional, Kim, Kyung-Seon, additional, Park, Mi-Hyun, additional, Shin, Hyoung-Doo, additional, Park, Byung Lae, additional, Kim, Tae-Ho, additional, Hong, Jung Min, additional, Park, Eui Kyun, additional, Kim, Duk Jae, additional, Oh, Bermseok, additional, Kimm, Kuchan, additional, Kim, Ghi Su, additional, and Lee, Jong-Young, additional

Published
2007
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380. Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype

Author

Kim, Kyung-Seon, primary, Kim, Ghi-Su, additional, Hwang, Joo-Yeon, additional, Lee, Hye-Ja, additional, Park, Mi-Hyun, additional, Kim, Kwang-joong, additional, Jung, Jongsun, additional, Cha, Hyo-Soung, additional, Shin, Hyoung Doo, additional, Kang, Jong-Ho, additional, Park, Eui Kyun, additional, Kim, Tae-Ho, additional, Hong, Jung-Min, additional, Koh, Jung-Min, additional, Oh, Bermseok, additional, Kimm, Kuchan, additional, Kim, Shin-Yoon, additional, and Lee, Jong-Young, additional

Published
2007
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384. Association of FLT3 Polymorphisms With Low BMD and Risk of Osteoporotic Fracture in Postmenopausal Women

Author

Koh, Jung-Min, primary, Oh, Bermseok, additional, Lee, Jong-Young, additional, Lee, Jong-Keuk, additional, Kimm, Kuchan, additional, Park, Byung Lae, additional, Shin, Hyoung Doo, additional, Lee, Il-Kwon, additional, Kim, Hyeoung-Joon, additional, Hong, Jung-Min, additional, Kim, Tae-Ho, additional, Kim, Ghi Su, additional, Kim, Shin-Yoon, additional, and Park, Eui Kyun, additional

Published
2007
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394. Gene expression profile of necrotizing enterocolitis model in neonatal mice.

Author

Jung, Kyuwhan, Kim, Jeong-Hyun, Cheong, Hyun Sub, Shin, Eun, Kim, Seong-Ho, Hwang, Ji-Yeon, Lee, Eunyoung, Yoon, Mi-Ok, Kim, Seong-Hee, Sio, Cherry Ann, Shin, Hyoung Doo, and Jung, Sung-Eun

Subjects
ANIMAL experimentation, ANIMAL populations, ANIMALS, HYPOXEMIA, BIOLOGICAL models, NEONATAL necrotizing enterocolitis, MICE, PROTEOLYTIC enzymes, GENE expression profiling
Abstract

Background: Necrotizing enterocolitis (NEC) characterized by intestinal necrosis is one of the most common gastrointestinal emergencies in newborns. The main purpose of this study was to evaluate the whole genome expression levels in a NEC mouse model controlled with breast milk.Methods: This study induced a NEC model in mice of gestational ages of 18-21 days by intensive hypoxic insult and permitted breast-feeding instead of formula feeding. After evaluating the NEC status in the small intestines of neonatal mice by histological examination, a genome-wide gene expression profile study was completed using microarray analysis.Results: A total of 72 genes (38 down-regulated and 34 up-regulated) were observed to have significantly different expression profiles in the NEC mouse model compared with the normal control animals, based on a significance at fold change ≥ 2 and P < 0.05. In particular, down-regulated Hist1h2aa and up-regulated Ube2i showed the most significant signals (P = 0.0008 for both genes). In an additional gene ontology analysis, the endopeptidase related categories (specifically, serine-type endopeptidase inhibitor activity, P = 8.95 × 10(-5); Pcorr = 0.008) appeared to affect NEC development in the mouse model.Conclusion: Although replications and functional evaluations are needed, our results suggest that several genes may have different expression profiles in the NEC mouse model. In particular, endopeptidase related genes (which are also known to be relevant to NEC), as identified through gene ontology analysis, may represent attractive targets for future research. [ABSTRACT FROM AUTHOR]

Published
2015
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395. Association of VARS2- SFTA2 polymorphisms with the risk of chronic hepatitis B in a Korean population.

Author

Cheong, Hyun Sub, Lee, Jeong ‐ Hoon, Yu, Su Jong, Yoon, Jung ‐ Hwan, Lee, Hyo ‐ Suk, Cheong, Jae Youn, Cho, Sung Won, Park, Neung Hwa, Park, Byung Lae, Namgoong, Suhg, Kim, Lyoung Hyo, Shin, Hyoung Doo, and Kim, Yoon ‐ Jun

Subjects
SINGLE nucleotide polymorphisms, CHRONIC hepatitis B, HEPATITIS B virus, CIRRHOSIS of the liver, LIVER cancer
Abstract

Background & Aims Hepatitis B virus ( HBV) infection is the most serious risk factor for chronic hepatitis B ( CHB), cirrhosis, and hepatocellular carcinoma. Recently, several genome-wide association studies ( GWASs) identified important variants associated with the risk of CHB in Asian populations. Specifically, our previous GWAS identified the VARS2- SFTA2 gene region as one of the genetic risk loci for CHB. Methods To further characterize this association and to isolate possible causal variants within it, we performed an additional association study by genotyping more SNPs in the vicinity of the VARS2 and SFTA2 genes. In all, 14 SNPs of VARS2- SFTA2 were analysed among a total of 3902 subjects (1046 cases and 2856 controls). Results Logistic regression analysis revealed that six SNPs, including the previously reported rs2532932, were significantly associated with the risk of CHB ( P = 1.7 × 10−10~0.002). Further linkage disequilibrium and conditional analysis identified two variants ( rs9394021 and rs2517459) as new markers of genetic risk factors for CHB rather than the reported SNP from our previous study ( rs2532932). To evaluate the cumulative risk for CHB based on all known genetic factors, genetic risk score ( GRS) were calculated. As anticipated, the distribution of the number of risk alleles in cases vs. controls clearly differed according to the GRS. Similarly, the odds ratios ( ORs) were increased ( OR = 0.32-3.97). Conclusion Our findings show that common variants in the VARS2- SFTA2 gene region are significantly associated with CHB in a Korean population, which may be useful in further understanding genetic susceptibility to CHB. [ABSTRACT FROM AUTHOR]

Published
2015
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398. Putative association of RUNX1 polymorphisms with IgE levels in a Korean population

Author

Chae, Soo-Cheon, primary, Park, Byung Lae, additional, Park, Choon-Sik, additional, Ryu, Ha-Jung, additional, Yang, Yun-Sik, additional, Lee, Soo Ok, additional, Choi, Yoo Hyun, additional, Kim, Eun Mi, additional, Uh, Soo Taek, additional, Kim, Young Hoon, additional, Kim, Ka-Kyung, additional, Oh, Bermseok, additional, Chung, Hun-Taeg, additional, Kimm, Kuchan, additional, and Shin, Hyoung Doo, additional

Published
2006
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399. Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women

Author

Kim, Duk Jae, primary, Park, Byung Lae, additional, Koh, Jung-Min, additional, Kim, Ghi Su, additional, Kim, Lyoung Hyo, additional, Cheong, Hyun Sup, additional, Shin, Hyoung Doo, additional, Hong, Jung-Min, additional, Kim, Tae-Ho, additional, Shin, Hong-In, additional, Park, Eui Kyun, additional, and Kim, Shin-Yoon, additional

Published
2006
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