Search

The chair-mounted passive trunk orthosis (CMPTO) is designed to enhance wheelchair safety for individuals with dystrophinopathy during their daily activities. Given the disease's progressive nature, it is crucial to ensure that assistive devices are carefully evaluated to prevent overexertion. This study aims to assess the CMPTO's user experience and its impact on fatigue-related psychophysiological measurements. We conducted electromyography (EMG) evaluations of four trunk muscles and assessed perceived exertion using the Borg CR-10 scale in 40 healthy subjects while they performed seated maximal reaching tasks with the CMPTO. Additionally, fifteen dystrophinopathy patients evaluated the CMPTO for usability with the System Usability Scale. Paired t-tests were employed to compare the median frequency (MDF) of EMG signals, the Wilcoxon signed-rank test for evaluating exertion, and the Mann–Whitney U test to compare the usability reported by patients to those of healthy subjects. The 4-way ANOVA revealed that MDF patterns were significantly influenced by task orientation for each muscle. The CMPTO did not cause a significant reduction in the MDF. Tasks requiring greater trunk rotation were perceived as more exhaustive. Patients reported acceptable usability with the CMPTO, with scores higher than those of healthy subjects. The CMPTO's usability was comprehensively evaluated in both healthy subjects and patients with dystrophinopathy. Our findings indicate that the CMPTO can be safely used by individuals with dystrophinopathy as an assistive device to improve seated comfort and functional abilities. [ABSTRACT FROM AUTHOR]

Due to massive adoption of social media, detection of users' depression through social media analytics bears significant importance, particularly for underrepresented languages, such as Bangla. This study introduces a well-grounded approach to identify depressive social media posts in Bangla, by employing advanced natural language processing techniques. The dataset used in this work, annotated by domain experts, includes both depressive and non-depressive posts, ensuring high-quality data for model training and evaluation. To address the prevalent issue of class imbalance, we utilised random oversampling for the minority class, thereby enhancing the model's ability to accurately detect depressive posts. We explored various numerical representation techniques, including Term Frequency -- Inverse Document Frequency (TF-IDF), Bidirectional Encoder Representations from Transformers (BERT) embedding and FastText embedding, by integrating them with a deep learning-based Convolutional Neural Network-Bidirectional Long Short-Term Memory (CNN-BiLSTM) model. The results obtained through extensive experimentation, indicate that the BERT approach performed better the others, achieving a F1-score of 84%. This indicates that BERT, in combination with the CNN-BiLSTM architecture, effectively recognises the nuances of Bangla texts relevant to depressive contents. Comparative analysis with the existing state-of-the-art methods demonstrates that our approach with BERT embedding performs better than others in terms of evaluation metrics and the reliability of dataset annotations. Our research significantly contributes to the development of reliable tools for detecting depressive posts in the Bangla language. By highlighting the efficacy of different embedding techniques and deep learning models, this study paves the way for improved mental health monitoring through social media platforms. [ABSTRACT FROM AUTHOR]

Adenoviruses are commonly found in chickens, and can be isolated from both sick and apparently healthy birds. Inclusion body hepatitis (IBH) is an acute disease primarily caused by (Fowl adeno virus) FAdV strains from groups D and E, including FAdV-8a serotype. Acknowledged for its immunosuppressive effects, we undertook an investigation into the early infection dynamics of IBH and its consequential impact on a fundamental vaccine widely employed in the poultry industry. Our study precisely examined the interplay between early IBH infection and the efficacy of a specific (Infectious bronchitis) IB vaccine. In this study, a total of 150 broiler chicks were divided into five groups, each consistedof 30 chicks. Group I received one dose of the IB variant vaccine, Group II and III received two doses (the first at 1-day-old and the second at 14-day-old), Group IV (control +ve) and Group V (control -ve). Groups I, II and IV were infected with IBH at 7-day-old. The evaluation encompassed diverse parameters, including clinical manifestations, mortality rates, and histopathological assessments of the liver, trachea, and kidney. Additionally, viral shedding of the IB vaccinal strain was examined. Our findings focus the detrimental impact of early IBH infection on avian organs and IB vaccinal strain shedding. Pronounced necrotic changes were observed in the tissues, coupled with an elevated viral shedding of the variant strain. These results collectively imply an augmented risk of potential outbreaks, emphasizing the need for a nuanced approach in managing IBH in the context of vaccination strategies. [ABSTRACT FROM AUTHOR]