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4,442 results on '"Robert Thomas"'

367. Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling

Author

Dhiabi, Marwa, primary, Bouattour, Ali, additional, Fakhfakh, Mehdi, additional, Abid, Souhir, additional, Paquin, Ludovic, additional, Robert, Thomas, additional, Bach, Stephane, additional, Bazureau, Jean-Pierre, additional, and Ammar, Houcine, additional

Published
2023
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368. Impact of acute hydrocephalus after aneurysmal SAH on longitudinal neuropsychological outcome

Author

Maschke, Svenja, primary, Germans, Menno, additional, Bijlenga, Philippe, additional, Maduri, Rodolfo, additional, Daniel, R.T., additional, Chiappini, Alessio, additional, Robert, Thomas, additional, Zeitlberger, A.M., additional, Goldberg, Johannes, additional, Bervini, David, additional, Bozinov, Oliver, additional, Keller, Emanuela, additional, Regli, Luca, additional, Stienen, Martin, additional, and Hostettler, I.C., additional

Published
2023
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370. Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: design, synthesis, bioactivity evaluation, and in silico studies

Author

Hasanvand, Zaman, primary, Oghabi Bakhshaiesh, Tayebeh, additional, Peytam, Fariba, additional, Firoozpour, Loghman, additional, Hosseinzadeh, Elaheh, additional, Motahari, Rasoul, additional, Moghimi, Setareh, additional, Nazeri, Elaheh, additional, Toolabi, Mahsa, additional, Momeni, Farhad, additional, Bijanzadeh, Hamidreza, additional, Khalaj, Ali, additional, Baratte, Blandine, additional, Josselin, Béatrice, additional, Robert, Thomas, additional, Bach, Stéphane, additional, Esmaeili, Rezvan, additional, and Foroumadi, Alireza, additional

Published
2023
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371. Complications And Multidimensional Outcome After Endovascular Versus Microsurgical Occlusion Of Ruptured Intracranial Aneurysms – Comparative Analysis Af A Swiss Multicenter Study

Author

Kälin, Vincens, primary, Stienen, Martin Nikolaus, additional, Velz, Julia, additional, Sebök, Martina, additional, May, Adrien, additional, Bijlenga, Philipp, additional, Maduri, Rodolfo, additional, Starnoni, Daniele, additional, Chiappini, Alessio, additional, Robert, Thomas, additional, Bonasia, Sara, additional, Goldberg, Johannes, additional, Fung, Christian, additional, Bervini, Davide, additional, Maldaner, Nikolai, additional, Zeitlberger, Anna Maria, additional, Bozinov, Oliver, additional, Keller, Emanuela, additional, Germans, Menno, additional, and Regli, Luca, additional

Published
2023
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372. From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

Author

Mast, Nicolas, primary, Erb, William, additional, Nauton, Lionel, additional, Moreau, Pascale, additional, Mongin, Olivier, additional, Roisnel, Thierry, additional, Macaigne, Margaux, additional, Robert, Thomas, additional, Bach, Stéphane, additional, Picot, Laurent, additional, Thiéry, Valérie, additional, Hurvois, Jean-Pierre, additional, and Mongin, Florence, additional

Published
2023
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376. Home-Time as a Surrogate Marker for Functional Outcome After Aneurysmal Subarachnoid Hemorrhage

Author

Stienen, Martin Nikolaus, Smoll, Nicolas Roydon, Fung, Christian, Goldberg, Johannes, Bervini, David, Maduri, Rodolfo, Chiappini, Alessio, Robert, Thomas, May, Adrien, Bijlenga, Philippe, Zumofen, Daniel, Roethlisberger, Michel, Seule, Martin Alexander, Marbacher, Serge, Fandino, Javier, Schatlo, Bawarjan, Schaller, Karl, Keller, Emanuela, Bozinov, Oliver, and Regli, Luca

Published
2018
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381. Nephrosclerosis in young patients with malignant hypertension

Author

Bureau, Côme, primary, Jamme, Matthieu, additional, Schurder, Juliet, additional, Bobot, Mickaël, additional, Robert, Thomas, additional, Couturier, Aymeric, additional, Karras, Alexandre, additional, Halimi, Jean-Michel, additional, Bellenfant, Xavier, additional, Rondeau, Eric, additional, and Mesnard, Laurent, additional

Published
2022
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383. Longitudinal neuropsychological assessment after aneurysmal subarachnoid hemorrhage and its relationship with delayed cerebral ischemia: a prospective Swiss multicenter study

Author

Stienen, Martin N., primary, Germans, Menno R., additional, Zindel-Geisseler, Olivia, additional, Dannecker, Noemi, additional, Rothacher, Yannick, additional, Schlosser, Ladina, additional, Velz, Julia, additional, Sebök, Martina, additional, Eggenberger, Noemi, additional, May, Adrien, additional, Haemmerli, Julien, additional, Bijlenga, Philippe, additional, Schaller, Karl, additional, Guerra-Lopez, Ursula, additional, Maduri, Rodolfo, additional, Beaud, Valérie, additional, Al-Taha, Khalid, additional, Daniel, Roy Thomas, additional, Chiappini, Alessio, additional, Rossi, Stefania, additional, Robert, Thomas, additional, Bonasia, Sara, additional, Goldberg, Johannes, additional, Fung, Christian, additional, Bervini, David, additional, Maradan-Gachet, Marie Elise, additional, Gutbrod, Klemens, additional, Maldaner, Nicolai, additional, Neidert, Marian C., additional, Früh, Severin, additional, Schwind, Marc, additional, Bozinov, Oliver, additional, Brugger, Peter, additional, Keller, Emanuela, additional, Marr, Angelina, additional, Roux, Sébastien, additional, Regli, Luca, additional, _, _, additional, Krayenbühl, Niklaus, additional, Esposito, Giuseppe, additional, Moiraghi, Alessandro, additional, Starnoni, Daniele, additional, Rocca, Alda, additional, Seule, Martin A., additional, Zeitlberger, Anna-Maria, additional, Weyerbrock, Astrid, additional, Hlavica, Martin, additional, and Müller, Mandy, additional

Published
2022
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386. Impact of Very Small Aneurysm Size and Anterior Communicating Segment Location on Outcome after Aneurysmal Subarachnoid Hemorrhage

Author

Roethlisberger, Michel, Aghlmandi, Soheila, Rychen, Jonathan, Chiappini, Alessio, Zumofen, Daniel W, Bawarjan, Schatlo, Stienen, Martin N, Fung, Christian, D'Alonzo, Donato, Maldaner, Nicolai, Steinsiepe, Valentin K, Corniola, Marco V, Goldberg, Johannes, Cianfoni, Alessandro, Robert, Thomas, Maduri, Rodolfo, Saliou, Guillaume, Starnoni, Daniele, Weber, Johannes, Seule, Martin A, Gralla, Jan, Bervini, David, Kulcsar, Zsolt, Burkhardt, Jan-Karl, Bozinov, Oliver, Remonda, Luca, Marbacher, Serge, Lövblad, Karl-Olof, Psychogios, Marios, Bucher, Heiner C, et al, and University of Zurich

Subjects
10043 Clinic for Neuroradiology, 610 Medicine & health, 2700 General Medicine
Published
2023

388. sj-pdf-1-cre-10.1177_02692155231183779 - Supplemental material for Walking ability of individuals fitted with transfemoral bone-anchored prostheses: A comparative study of gait parameters

Author

Ranaldi, Simone, Naaim, Alexandre, Marchis, Cristiano De, Robert, Thomas, Dumas, Raphael, Conforto, Silvia, and Frossard, Laurent

Subjects
Neurology and Neuromuscular Diseases, FOS: Clinical medicine, Orthopaedics, Sports Medicine
Abstract

Supplemental material, sj-pdf-1-cre-10.1177_02692155231183779 for Walking ability of individuals fitted with transfemoral bone-anchored prostheses: A comparative study of gait parameters by Simone Ranaldi, Alexandre Naaim, Cristiano De Marchis, Thomas Robert, Raphael Dumas, Silvia Conforto and Laurent Frossard in Clinical Rehabilitation

Published
2023
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390. Successful weaning versus permanent cerebrospinal fluid diversion after aneurysmal subarachnoid hemorrhage: post hoc analysis of a Swiss multicenter study

Author

El-Garci, Ahmed, Zindel-Geisseler, Olivia, Dannecker, Noemi, Rothacher, Yannick, Schlosser, Ladina, Zeitlberger, Anna, Velz, Julia, Sebök, Martina, Eggenberger, Noemi, May, Adrien, Bijlenga, Philippe, Guerra-Lopez, Ursula, Maduri, Rodolfo, Beaud, Valérie, Starnoni, Daniele, Chiappini, Alessio, Rossi, Stefania, Robert, Thomas, Bonasia, Sara, Goldberg, Johannes, Fung, Christian, Bervini, David, Gutbrod, Klemens, Maldaner, Nicolai, Früh, Severin, Schwind, Marc, Bozinov, Oliver, Neidert, Marian C, Brugger, Peter, Keller, Emanuela, Germans, Menno R, Regli, Luca, Hostettler, Isabel C, and Stienen, Martin N

Subjects
610 Medicine & health
Abstract

OBJECTIVE Acute hydrocephalus is a frequent complication after aneurysmal subarachnoid hemorrhage (aSAH). Among patients needing CSF diversion, some cannot be weaned. Little is known about the comparative neurological, neuropsychological, and health-related quality-of-life (HRQOL) outcomes in patients with successful and unsuccessful CSF weaning. The authors aimed to assess outcomes of patients by comparing those with successful and unsuccessful CSF weaning; the latter was defined as occurring in patients with permanent CSF diversion at 3 months post-aSAH. METHODS The authors included prospectively recruited alert (i.e., Glasgow Coma Scale score 13-15) patients with aSAH in this retrospective study from six Swiss neurovascular centers. Patients underwent serial neurological (National Institutes of Health Stroke Scale), neuropsychological (Montreal Cognitive Assessment), disability (modified Rankin Scale), and HRQOL (EuroQol-5D) examinations at < 72 hours, 14-28 days, and 3 months post-aSAH. RESULTS Of 126 included patients, 54 (42.9%) developed acute hydrocephalus needing CSF diversion, of whom 37 (68.5%) could be successfully weaned and 17 (31.5%) required permanent CSF diversion. Patients with unsuccessful weaning were older (64.5 vs 50.8 years, p = 0.003) and had a higher rate of intraventricular hemorrhage (52.9% vs 24.3%, p = 0.04). Patients who succeed in restoration of physiological CSF dynamics improve on average by 2 points on the Montreal Cognitive Assessment between 48-72 hours and 14-28 days, whereas those in whom weaning fails worsen by 4 points (adjusted coefficient 6.80, 95% CI 1.57-12.04, p = 0.01). They show better neuropsychological recovery between 48-72 hours and 3 months, compared to patients in whom weaning fails (adjusted coefficient 7.60, 95% CI 3.09-12.11, p = 0.02). Patients who receive permanent CSF diversion (ventriculoperitoneal shunt) show significant neuropsychological improvement thereafter, catching up the delay in neuropsychological improvement between 14-28 days and 3 months post-aSAH. Neurological, disability, and HRQOL outcomes at 3 months were similar. CONCLUSIONS These results show a temporary but clinically meaningful cognitive benefit in the first weeks after aSAH in successfully weaned patients. The resolution of this difference over time may be due to the positive effects of permanent CSF diversion and underlines its importance. Patients who do not show progressive neuropsychological improvement after weaning should be considered for repeat CT imaging to rule out chronic (untreated) hydrocephalus.

Published
2023
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391. Branding Corporate Criminals

Author

William Robert Thomas and Mihailis Diamantis

Subjects
History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering
Published
2023

397. Computed tomography angiography spot sign predicts intraprocedural aneurysm rupture in subarachnoid hemorrhage

Author

Burkhardt, Jan-Karl, Neidert, Marian Christoph, Stienen, Martin Nikolaus, Schöni, Daniel, Fung, Christian, Roethlisberger, Michel, Corniola, Marco Vincenzo, Bervini, David, Maduri, Rodolfo, Valsecchi, Daniele, Tok, Sina, Schatlo, Bawarjan, Bijlenga, Philippe, Schaller, Karl, Bozinov, Oliver, Regli, Luca, Fathi, Ali-Reza, Fandino, Javier, Marbacher, Serge, D’Alonzo, Donato, Kerkeni, Hassen, Soleman, Jahuda, Coluccia, Daniel, Muroi, Carl, Danura, Hiroki, Schmid, Nicole, Zumofen, Daniel, Röthlisberger, Michel, Mariani, Luigi, Guzman, Rahael, Monsch, Andreas U., Bläsi, Stephan, Fung, Christian, Bervini, David, Beck, Jürgen, Raabe, Andreas, Goldberg, Johannes, Schöni, Daniel, Gralla, Jan, Zweifel-Zehnder, Antoinette, Gutbrod, Klemens, Müri, Rene, Maduri, Rodolfo, Daniel, Roy Thomas, Starnoni, Daniele, Messerer, Mahmoud, Levivier, Marc, Beaud, Valérie, Valsecchi, Daniele, Arrighi, Marta, Venier, Alice, Reinert, Michael, Kuhlen, Dominique E., Robert, Thomas, Rossi, Stefania, Sacco, Leonardo, Bijlenga, Philippe, Corniola, Marco, Schaller, Karl, Chicherio, Christian, Seule, Martin A., Ferrari, Andrea, Weyerbrock, Astrid, Hlavica, Martin, Fournier, Jean-Yves, Früh, Severin, Schatlo, Bawarjan, Burkhardt, Jan-Karl, Stienen, Martin N., Keller, Emanuela, Regli, Luca, Bozinov, Oliver, Maldaner, Nicolai, Tok, Sina, Neidert, Marian C., Brugger, Peter, Mondadori, Christian, and on behalf of the Swiss SOS study group

Published
2017
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400. The immobility of the low-skilled and unemployed in the United Kingdom

Author

Kitching, Robert Thomas

Subjects
331, Labour studies
Abstract

As the economy of the United Kingdom has improved in the latter half of the 1980s, the distribution of new employment opportunities remains poorly matched to the distribution of the unemployed. With the decline in regional policy in recent years, much government rhetoric has been directed towards encouraging the unemployed and others to move from one part of the country to another in response to job opportunities. Yet the unemployed and the low-skilled continue to exhibit lower rates of mobility than the population as a whole, and there is evidence of socio-economic polarisation in migration. The thesis argues that for many low-skilled, low-paid and unemployed people in the United Kingdom immobility is a rational response to their labour market situation, even when conditions might suggest otherwise. It studies the decision to migrate at the level of the household, set within the interacting spheres of opportunity, aspiration and constraint. The methods of research allow comparisons of manual and non-manual workers, and of two contrasting labour and housing areas, Liverpool and Reading. Quantitative and qualitative methodologies are combined Interview survey and group discussion techniques are combined to examine the relations between social class and immobility, and the influence of local labour and housing markets and community affiliations upon individual and household migration decisions. The survey results demonstrate that migration actions and aspirations are related to position within the local housing and labour market, to housing and employment histories and to stages in household development. The need to look at the household as a dynamic unit is shown, since its needs and those of its members will change over time. The analysis concludes by demonstrating that households balance aspirations, opportunities and constraints, creating a series of 'windows' when migration is preferred though not always a possible option. Whether or not a household will respond by migration depends upon how it balances the elements in decision, particularly those in housing, employment and attitude towards the local community. It concludes that for most low-skilled and unemployed households the most rational course of action is to stay put, despite labour market theories and government exhortations to the contrary.

Published
1990

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