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Your search keyword '"COECKE SANDRA"' showing total 235 results

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235 results on '"COECKE SANDRA"'

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201. New approach methodologies (NAMs) for human-relevant biokinetics predictions. Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

202. Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.

204. Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.

205. Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance.

206. Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems.

207. Good cell culture practices &in vitro toxicology.

208. Practical Aspects of Designing and Conducting Validation Studies Involving Multi-study Trials.

209. Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.

210. International Harmonization and Cooperation in the Validation of Alternative Methods.

211. Validation of Alternative In Vitro Methods to Animal Testing: Concepts, Challenges, Processes and Tools.

212. Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data.

213. Stem cell-derived systems in toxicology assessment.

214. Differentiation-Promoting Medium Additives for Hepatocyte Cultivation and Cryopreservation.

215. PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.

216. Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches.

217. Assessment of an automated in vitro basal cytotoxicity test system based on metabolically-competent cells.

218. Three-dimensional HepaRG model as an attractive tool for toxicity testing.

219. Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.

220. ECVAM and new technologies for toxicity testing.

221. Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

222. Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.

223. Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.

224. mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach.

225. Proposal for a Brazilian centre on alternative test methods.

226. Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis.

227. Patterned growth and differentiation of human cord blood-derived neural stem cells on bio-functionalized surfaces.

228. Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63.

229. Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.

230. The value of alternative testing for neurotoxicity in the context of regulatory needs.

231. Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54.

232. Expression of the membrane complement regulatory proteins (CD55 and CD59) in human thymus.

233. Toxicokinetics and metabolism.

234. Metabolism-mediated neurotoxicity: the significance of genetically engineered cell lines and new three-dimensional cell cultures.

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