351. A scoping review on pediatric sepsis prediction technologies in healthcare.
- Author
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Tennant, Ryan, Graham, Jennifer, Kern, Juliet, Mercer, Kate, Ansermino, J. Mark, and Burns, Catherine M.
- Subjects
MEDICAL information storage & retrieval systems ,PREDICTION models ,ARTIFICIAL intelligence ,CINAHL database ,LOGISTIC regression analysis ,DESCRIPTIVE statistics ,SYSTEMATIC reviews ,MEDLINE ,SEPSIS ,TECHNOLOGY ,MACHINE learning ,DATA analysis software ,ONLINE information services ,CHILDREN - Abstract
This scoping review evaluates recent advancements in data-driven technologies for predicting non-neonatal pediatric sepsis, including artificial intelligence, machine learning, and other methodologies. Of the 27 included studies, 23 (85%) were single-center investigations, and 16 (59%) used logistic regression. Notably, 20 (74%) studies used datasets with a low prevalence of sepsis-related outcomes, with area under the receiver operating characteristic scores ranging from 0.56 to 0.99. Prediction time points varied widely, and development characteristics, performance metrics, implementation outcomes, and considerations for human factors—especially workflow integration and clinical judgment—were inconsistently reported. The variations in endpoint definitions highlight the potential significance of the 2024 consensus criteria in future development. Future research should strengthen the involvement of clinical users to enhance the understanding and integration of human factors in designing and evaluating these technologies, ultimately aiming for safe and effective integration in pediatric healthcare. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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