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A retrospective study was made of cases of colorectal cancer and controls using 571 cases from various hospitals in Valencia (Spain) and 1,497 controls from the general population with similar sex, age and residence. The relative risks (RR) and levels of statistical significance of various "risk factors" presumably linked to this cancer were calculated. It was associated with: smoking, the Quetelet index (which relates weight and height), chronic constipation and, possibly, sedentary life style, previous cholecystectomy and biliary lithiasis. No association was observed with: civil status, weight, coffee and alcohol intake, or professional status.

We have reviewed the mortality from laryngeal cancer in Spain (1951-1983). An evident increase of the tendency for males has been observed, while an stabilization in females, with lower rates, has been appreciated. It is reflected in the increase of the sex ratio along the studied period, specially since 1970. Concerning the morbidity, through hospital diagnostic data in Spain, as much the absolute numbers as the corresponding morbidity rates have been clearly increasing in males, specially during the last years of our study (1977-1985).

In review of the rising bladder cancer mortality rate in Spain and its involvement in connection with other "risk factors", according to recent contributions, we proceeded to review these factors involved and to carry out an epidemiological study describing its mortality from 1968 to 1982, through specific mortality rates per hundred thousand in males and females, as well as the study by age groups from 50 upwards, concentrating on more highly affected ages. We also carried out transverse studies for the three years 1968, 1975 and 1982 and reviewed the evolution of mortality in accordance with the chorts of births. On the whole, we observe a continual rise in mortality due to this cancer, at a much higher level in the masculine sex, and we make interpretation as to its association with "risk factors" connected with life style.