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A case of cardiomyopathy of pregnancy where death was due to profound cerebral ischaemia is reported. Two other similar cases are mentioned. Awareness of this syndrome may help the pathologist to establish the cause of coma and death in pregnancy when clinical studies have failed to indicate the cause. It is suggested that electrocardiography should be carried out in all cases of apparent cerebrovascular accidents that occur during pregnancy or the puerperium as there may be an underlying cardiomyopathy. The nature and the possible aetiology of cardiomyopathy of pregnancy are briefly discussed.

Three weeks after admission to a maternity hospital for observation following minor antepartum haemorrhage, a primiparous patient aged 22 suffered a sudden left hemiplegia and became comatose. Congestive cardiac failure ensued and because of the subsequent severe hypoxaemia she was transferred to the hyperbaric oxygen unit at the Western Infirmary, Glasgow, where it was found possible to improve her condition by means of oxygen at increased pressure. A caesarean section was w successfully performed in the hyperbaric chamber, and a normal live female infant was delivered. Though the patient's general condition improved she never regained consciousness and died almost three months later. Necropsy confirmed the clinical diagnosis of cardiomyopathy of pregnancy with severe ischaemic changes in the brain.

A case of acquired hepatocerebral degeneration secondary to biliary cirrhosis is described. It differs from the conventional type because of the clinical predominance of cerebellar symptomatology and because the principal neuropathological abnormalities were restricted to the pallidum and to the cerebellum.