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The thiopyran unit of the title molecule, C17H15ClO2S, is in chair form. A crystallographic mirror plane bisects the molecule, passing through the O=S and the opposite C=O atoms of the central ring, with statistical disorder of the Cl atom. The geometry around the S atom is tetrahedral and the carbonyl C is planar. The 4-chlorophenyl group at the 2 position and the phenyl ring at the 6 position have equatorial orientations. Intermolecular C—H...O and C—H...Cl hydrogen bonds are found in the crystal structure. In addition, there is a short O...C intermolecular contact [2.970 (5) Å].

In the title molecule, C18H16F3N5O2, the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered over two positions; the site-occupancy factors are ca 0.53 and 0.47. Intermolecular C—H...F hydrogen bonding is found in the crystal structure. Furthermore, C—H...O and C—H...N intramolecular contacts are also present.

In the title molecule, C16H13Cl2FN2OS, the dihedral angle between the thiophene and benzene rings is 80.34 (12)°. The pyrazoline ring is in an envelope conformation, and the plane through the four coplanar atoms makes dihedral angles of 85.13 (9) and 6.89 (10)° with the thiophene and benzene rings, respectively. The C and O atoms of the acetyl group are nearly coplanar with the attached pyrazoline ring. In the crystal structure, inversion dimers arise from pairs of intermolecular C—H...O hydrogen bonds. A short intermolecular Cl...S contact of 3.4250 (13) Å is also found.

In the title molecule, C13H13NO, the dihedral angle between the benzene and pyrrole rings is 1.05 (5)°. The cycloheptene ring adopts a slightly distorted boat conformation. In the crystal structure, intermolecular N—H...O hydrogen bonds form centrosymmetric dimers. A C—H...π interaction, involving the benzene ring, is also found in the structure.

In the title molecule, C27H24N2O, the piperidine ring adopts a boat conformation. The acetyl group at position 1 has a bisectional orientation. The two phenyl rings attached to the piperidine ring at positions 2 and 6 have bisectional and axial orientations, respectively, and make a dihedral angle of 75.27 (10)°. The phenylacetonitrile group at position 4 has an equatorial orientation. Molecules are linked by C—H...N, C—H...O intermolecular and C—H...π interactions. A C—H...O intramolecular interaction is also found in the molecule.

The asymmetric unit of the title compound, C14H10Br2N6O, contains two crystallographically independent molecules. The pyrazole ring of one molecule makes dihedral angles of 22.0 (3) and 3.5 (3)° with the pyrimidine and benzene rings, respectively; the corresponding values in the other molecule are 9.2 (3) and 2.1 (3)°, respectively. The molecules are linked by N—H...O, C—H...N and C—H...Br hydrogen bonds.

The piperidine ring of the title mol­ecule, C20H15Cl2N3, is in a chair form. The dihedral angle between the two chloro­phenyl rings is 38.4 (1)°. The benzene rings are in equatorial orientations. The malononitrile group is planar. Intra­molecular C—H⋯Cl and C—H⋯N hydrogen bonds are found in the crystal structure.

The piperidine ring of the title mol­ecule, C21H25NO2, is in the chair form. The dihedral angle between the two phenyl rings is 46.1 (1)°. All the substituents of the central ring have equatorial orientations. The crystal packing is stabilized by C—H⋯O inter­molecular inter­actions.

In the title mol­ecule, C18H17N3O3S, the dihedral angle between the two benzene rings is 72.8 (1)°. C—H⋯O and C—H⋯N hydrogen bonds are found in the crystal structure.

The piperidine ring of the title compound, C25H23NO2, is in a distorted boat form. The phenyl ring at position 2 makes a dihedral angle of 80.6 (1)° with the phenyl ring of the benzyl group at position 3, and 61.2 (1)° with the phenyl ring at position 6. The dihedral angle between the phenyl ring of the benzyl group and the phenyl ring at position 6 is 84.2 (1)°. The formyl group and the phenyl ring at position 6 have equatorial orientations. The phenyl ring at position 2 and the benzyl group at position 3 have axial orientations. C—H⋯O and C—H⋯π hydrogen bonds are found in the crystal structure.

The title mol­ecule, C9H7ClN2, is essentially planar, except for two methyl H atoms. The dihedral angle between the benzene ring and the pyrazine ring is 0.48 (7)°. A weak C—H⋯π inter­action is found in the crystal structure and there are no classical hydrogen bonds.

In the title mol­ecule, C13H9FOS, the dihedral angle between the thio­phene ring and the benzene ring is 10.8 (1)°. The crystal packing is stabilized by C—H⋯O and C—H⋯π hydrogen bonds.

The molecule of the title compound, C10H10BrN5O2, is planar, except for the amino and carboxyl­ate groups. The mol­ecules are linked by inter­molecular C—H⋯O and N—H⋯N hydrogen bonds, and by slipped π–π stacking between symmetry-related pyrazole and pyrimidine rings [centroid-to-centroid distance 3.512 (1) A, interplanar distance 3.391 A and offset angle 15.1°]. Intra­molecular N—H⋯N and N—H⋯O hydrogen bonds stabilize the planar conformation.