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4,676 results on '"A Cerami"'

353. Risk factors for post-COVID cognitive dysfunctions: the impact of psychosocial vulnerability.

Author

Picascia, Marta, Cerami, Chiara, Panzavolta, Andrea, Bernini, Sara, Calculli, Alessandra, Regalbuto, Simone, and Pisani, Antonio

Subjects
*COVID-19 pandemic, *COGNITION disorders, *COVID-19, *POST-acute COVID-19 syndrome, *LONELINESS, *POST-traumatic stress
Abstract

Background: Cognitive dysfunction is a well-established manifestation of the post-COVID syndrome. Psychological vulnerability to stressors can modify disease trajectories, causing long-term risk for negative outcomes. Nonetheless, how premorbid risk factors and response to stressor affect neuropsychological changes is still incompletely understood. In this study, we explored the impact of psychosocial variables on cognitive functioning in a post-COVID sample. Methods: All subjects were submitted to a comprehensive neuropsychological battery and an assessment of perceived loneliness, post-traumatic stress, and changes in anxiety and depression levels. A social vulnerability index was also calculated. The set of psycho-social variables was reduced to two Principal Component Analysis (PCA) components: distress and isolation. Results: Forty-five percent of individuals showed cognitive impairments, with predominant memory and executive deficits. Post-traumatic stress disorder was clinically relevant in 44% of the sample. Social vulnerability scores of the sample were comparable to those of general population. The individual performance in learning and response initiation/suppression was directly related to distress component, encasing anxiety, stress, and depression measures. Conclusion: These findings suggest that psychosocial assessment of post-COVID patients can detect fragile individuals at risk of cognitive impairments. Dedicated psychological support services may play a useful role in the prevention of post-COVID cognitive dysfunction. [ABSTRACT FROM AUTHOR]

Published
2023
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358. A longitudinal investigation of dietary diversity during the COVID-19 pandemic in Mandinka households in Kanifing, Brikama, and the West Kiang region in The Gambia

Author

Sidebottom, Richard, Wassie, Solomon Bizuayehu, Cerami, Carla, Jallow, Momodou W, Fennell, Shailaja, Dalzell, Sarah, and Apollo - University of Cambridge Repository

Subjects
nutrition, Nutrition and Dietetics, dietary diversity, Endocrinology, Diabetes and Metabolism, COVID-19, coping mechanisms, food security, Food Science
Abstract

Peer reviewed: True, Acknowledgements: The authors gratefully acknowledge the assistance of the data collection and data management teams at MRC Gambia/London School of Hygiene and Tropical Medicine, The Gambia., The Covid pandemic has exposed fissures of inequality through heightened food insecurity and nutritional deficiency for vulnerable social cohorts with limited coping mechanisms. Given the multi-dimensional pathways through which its effects have been felt, several researchers have highlighted the need to analyse the pandemic in specific contexts. Using random and fixed effect regression models, this study analyzed longitudinal survey data collected from 103 Mandinka households in rural and urban Gambia. The study employed convenience and snowball sampling and involved the monthly collection of detailed income, food consumption, expenditure, sourcing, migration, health, and coping mechanism data through mobile phone interviews which yielded 676 observations. Food insecurity was manifest in terms of quality, not quantity, and spread unevenly across food types and households. Dietary outcomes and sourcing strategies were associated with location, improved sanitation, household size, changes in monthly income, Covid policy stringency, and Covid cases but these associations varied by food group. Staples were the most frequently consumed food group, and dark green vegetables were the least. Rural communities were more likely to eat more healthy millets but much less likely to consume dairy products or roots and tubers. Access to own production was also important for Vitamin A-rich foods but higher incomes and markets were key for protein and heme-iron-rich foods. Tighter Covid policy stringency was negatively associated with dietary diversity and, along with fear of market hoarding, was positively associated with reliance on a range of consumption and production coping mechanisms. Resilience was higher in larger households and those with improved water and sanitation. The number of Covid cases was associated with higher consumption of protein-rich foods and greater reliance on own produced iron-rich foods. Very few households received Government aid and those that did already had access to other income sources. Our findings suggest that the nature of food insecurity may have evolved over time during the pandemic. They also reiterate not only the importance of access to markets and employment but also that the capacity to absorb affordability shocks and maintain food choices through switching between sources for specific nutritious food groups varied by household and location.

Published
2022
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359. On decidability of concept satisfiability in Description Logic with product semantics

Author

Francesc Esteva and Marco Cerami

Subjects
Reduction (recursion theory), Logic, Finite model property, Satisfiability, First-order logic, Decidability, Algebra, TheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGES, Description logic, Artificial Intelligence, Computer Science::Logic in Computer Science, Product (mathematics), Finitary, Mathematics
Abstract

The aim of the present paper is to prove that concept validity and positive satisfiability with an empty ontology in the Fuzzy Description Logic IALE, under standard product semantics and with respect to quasi-witnessed models, are decidable. In our framework we are not considering reasoning tasks over ontologies. The proof of our result consists in reducing the problem to a finitary consequence problem in propositional product logic with Monteiro-Baaz delta operator, which is known to be decidable. Product FDL and first order logic are known not to enjoy the finite model property, so we cannot restrict to finite interpretations. Thus, in order to obtain our result, we need to codify infinite interpretations using a finite number of propositional formulas. Such result was conjectured in [10], but the proof given was subsequently found incorrect. In the present work an improved reduction algorithm is proposed and a proof of the same result is provided.

Published
2022

361. A Call for Drug Therapies for the Treatment of Social Behavior Disorders in Dementia: Systematic Review of Evidence and State of the Art

Author

Chiara Cerami, Giulia Perini, Andrea Panzavolta, Matteo Cotta Ramusino, and Alfredo Costa

Subjects
Organic Chemistry, Social Behavior Disorders, General Medicine, Oxytocin, Catalysis, Computer Science Applications, Inorganic Chemistry, Cognition, Frontotemporal Dementia, Humans, Physical and Theoretical Chemistry, Social Behavior, Molecular Biology, Spectroscopy
Abstract

Growing evidence supports the presence of social cognition deficits and social behavior alterations in major and minor neurocognitive disorders (NCDs). Even though the ability to identify socio-emotional changes has significantly improved in recent years, there is still no specific treatment available. Thus, we explored evidence of drug therapies targeting social cognition alterations in NCDs. Papers were selected according to PRISMA guidelines by searching on the PubMed and Scopus databases. Only papers reporting information on pharmacological interventions for the treatment of social cognition and/or social behavioral changes in major and/or minor NCDs were included. Among the 171 articles entered in the paper selection, only 9 papers were eligible for the scope of the review. Trials testing pharmacological treatments for socio-emotional alterations in NCDs are poor and of low-medium quality. A few attempts with neuroprotective, psychoactive, or immunomodulating drugs have been made. Oxytocin is the only drug specifically targeting the social brain that has been tested with promising results in frontotemporal dementia. Its beneficial effects in long-term use have yet to be evaluated. No recommendation can currently be provided. There is a long way to go to identify and test effective targets to treat social cognition changes in NCDs for the ultimate benefit of patients and caregivers.

Published
2022

362. Circulation of respiratory viruses during the COVID-19 pandemic in The Gambia

Author

S. Jarju, E. Senghore, H. Brotherton, A. Saidykhan, S. Jallow, E. Krubally, E. Sinjanka, M.N. Ndene, F. Bajo, M. Sanyang, B. Saidy, A Bah, K. Forrest, E. Clarke, U. D’Alessandro, E. Usuf, C. Cerami, A. Roca, B. Kampmann, and T. I. de Silva

Abstract

SummaryIn many countries, non-pharmaceutical interventions to limit SARS-CoV-2 transmission resulted in significant reductions in other respiratory viruses. However, similar data from Africa are limited. We explored the extent to which viruses such as influenza and rhinovirus co-circulated with SARS-CoV-2 in The Gambia during the COVID-19 pandemic. Between April 2020 and March 2022, respiratory viruses were detected using RT-PCR in nasopharyngeal swabs from 1397 participants with influenza-like illness. Overall virus positivity was 44.2%, with prevalence higher in children 50 years (39.9%), p50 years (24.3%), p50 years (6.3%), p

Published
2022
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363. Early Identification of Different Behavioral Phenotypes in the Behavioral Variant of Frontotemporal Dementia with the Aid of the Mini-Frontal Behavioral Inventory (mini-FBI)

Author

Chiara Cerami, Elena Perdixi, Claudia Meli, Alessandra Marcone, Michele Zamboni, Sandro Iannaccone, and Alessandra Dodich

Subjects
Psychiatry and Mental health, Clinical Psychology, Phenotype, Alzheimer Disease, General Neuroscience, Frontotemporal Dementia, Humans, General Medicine, Behavioral Symptoms, Geriatrics and Gerontology, Neuropsychological Tests
Abstract

Background: The Frontal Behavioral Inventory (FBI) is a questionnaire designed to quantify behavioral changes in frontotemporal dementia (FTD). Literature showed heterogeneous FBI profiles in FTD versus Alzheimer’s disease (AD) with variable occurrence of positive and negative symptoms. Objective: In this study, we constructed a short FBI version (i.e., mini-FBI) with the aim to provide clinicians with a brief tool for the identification of early behavioral changes in behavioral variant of FTD (bvFTD), also facilitating the differential diagnosis with AD. Methods: 40 bvFTD and 33 AD patients were enrolled. FBI items were selected based on internal consistency and exploratory factor analysis. Convergent validity of mini-FBI was also assessed. A behavioral index (i.e., B-index) representing the balance between positive and negative mini-FBI symptoms was computed in order to analyze its distribution in bvFTD through a cluster analysis and to compare performance among patient groups. Results: The final version of the mini-FBI included 12 items, showing a significant convergent validity with the Neuropsychiatric Inventory scores (rp = 0.61, p

Published
2022

365. Biology of Anemia: A Public Health Perspective

Author

Brittenham, Gary M., Moir-Meyer, Gemma, Abuga, Kelvin Mokaya, Datta-Mitra, Ananya, Cerami, Carla, Green, Ralph, Pasricha, Sant-Rayn, and Atkinson, Sarah H.

Abstract

Our goal is to present recent progress in understanding the biological mechanisms underlying anemia from a public health perspective. We describe important advances in understanding common causes of anemia and their interactions, including iron deficiency (ID), lack of other micronutrients, infection, inflammation, and genetic conditions. ID develops if the iron circulating in the blood cannot provide the amounts required for red blood cell production and tissue needs. ID anemia develops as iron-limited red blood cell production fails to maintain the hemoglobin concentration above the threshold used to define anemia. Globally, absolute ID (absent or reduced body iron stores that do not meet the need for iron of an individual but may respond to iron supplementation) contributes to only a limited proportion of anemia. Functional ID (adequate or increased iron stores that cannot meet the need for iron because of the effects of infection or inflammation and does not respond to iron supplementation) is frequently responsible for anemia in low- and middle-income countries. Absolute and functional ID may coexist. We highlight continued improvement in understanding the roles of infections and inflammation in causing a large proportion of anemia. Deficiencies of nutrients other than iron are less common but important in some settings. The importance of genetic conditions as causes of anemia depends upon the specific inherited red blood cell abnormalities and their prevalence in the settings examined. From a public health perspective, each setting has a distinctive composition of components underlying the common causes of anemia. We emphasize the coincidence between regions with a high prevalence of anemia attributed to ID (both absolute and functional), those with endemic infections, and those with widespread genetic conditions affecting red blood cells, especially in sub-Saharan Africa and regions in Asia and Oceania.

Published
2023
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367. Biomarker-based stability in limbic-predominant amnestic mild cognitive impairment

Author

Roberto Santangelo, Giuseppe Magnani, C Cerami, Daniela Perani, Massimo Filippi, Alzheimer’s Disease Neuroimaging Initiative, Sandro Iannaccone, Luca Presotto, Giacomo Tondo, Giulia Carli, Maria Vittoria Mattoli, Tondo, G., Carli, G., Santangelo, R., Mattoli, M. V., Presotto, L., Filippi, M., Magnani, G., Iannaccone, S., Cerami, C., Perani, D., Tondo, G, Carli, G, Santangelo, R, Mattoli, M, Presotto, L, Filippi, M, Magnani, G, Iannaccone, S, Cerami, C, and Perani, D

Subjects
Oncology, medicine.medical_specialty, behavioral disciplines and activities, cerebrospinal fluid, 03 medical and health sciences, 0302 clinical medicine, mild cognitive impairment, Alzheimer Disease, Fluorodeoxyglucose F18, Internal medicine, mental disorders, medicine, Dementia, Humans, Cognitive Dysfunction, 030212 general & internal medicine, limbic-predominant, Retrospective Studies, Fluorodeoxyglucose, business.industry, tauopathy, Area under the curve, Brain, F]FDG-PET, Retrospective cohort study, medicine.disease, Clinical trial, Neurology, Positron-Emission Tomography, Cohort, Biomarker (medicine), Neurology (clinical), Tauopathy, business, [, 030217 neurology & neurosurgery, Biomarkers, medicine.drug
Abstract

Background: The amnestic presentation of mild cognitive impairment (aMCI) represents the most common prodromal stage of Alzheimer's disease (AD) dementia. There is, however, some evidence of aMCI with typical amnestic syndrome but showing long-term clinical stability. The ability to predict stability or progression to dementia in the aMCI condition is important, particularly for the selection of candidates in clinical trials. We aimed to establish the role of in vivo biomarkers, as assessed by cerebrospinal fluid (CSF) measures and [18F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging, in predicting prognosis in a large aMCI cohort. Methods: We conducted a retrospective study, including 142 aMCI subjects who had a long follow-up (4–19years), baseline CSF data and [18F]FDG-PET scans individually assessed by validated voxel-based procedures, classifying subjects into either limbic-predominant or AD-like hypometabolism patterns. Results: The two aMCI cohorts were clinically comparable at baseline. At follow-up, the aMCI group with a limbic-predominant [18F]FDG-PET pattern showed clinical stability over a very long follow-up (8.20±3.30years), no decline in Mini-Mental State Examination score, and only 7% conversion to dementia. Conversely, the aMCI group with an AD-like [18F]FDG-PET pattern had a high rate of dementia progression (86%) over a shorter follow-up (6.47±2.07years). Individual [18F]FDG-PET hypometabolism patterns predicted stability or conversion with high accuracy (area under the curve=0.89), sensitivity (0.90) and specificity (0.89). In the limbic-predominant aMCI cohort, CSF biomarkers showed large variability and no prognostic value. Conclusions: In a large series of clinically comparable subjects with aMCI at baseline, the specific [18F]FDG-PET limbic-predominant hypometabolism pattern was associated with clinical stability, making progression to AD very unlikely. The identification of a biomarker-based benign course in aMCI subjects has important implications for prognosis and in planning clinical trials.

Published
2021

368. Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting

Author

Daniela Perani, Pasquale Anthony Della Rosa, Chiara Cerami, Francesca Gallivanone, Federico Fallanca, Emilia Giovanna Vanoli, Andrea Panzacchi, Flavio Nobili, Sabina Pappatà, Alessandra Marcone, Valentina Garibotto, Isabella Castiglioni, Giuseppe Magnani, Stefano F. Cappa, and Luigi Gianolli

Subjects
FDG-PET imaging, Statistical Parametrical Mapping, Voxel-based analysis, Dementia diagnosis, Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429
Abstract

Diagnostic accuracy in FDG-PET imaging highly depends on the operating procedures. In this clinical study on dementia, we compared the diagnostic accuracy at a single-subject level of a) Clinical Scenarios, b) Standard FDG Images and c) Statistical Parametrical (SPM) Maps generated via a new optimized SPM procedure. We evaluated the added value of FDG-PET, either Standard FDG Images or SPM Maps, to Clinical Scenarios. In 88 patients with neurodegenerative diseases (Alzheimer's Disease—AD, Frontotemporal Lobar Degeneration—FTLD, Dementia with Lewy bodies—DLB and Mild Cognitive Impairment—MCI), 9 neuroimaging experts made a forced diagnostic decision on the basis of the evaluation of the three types of information. There was also the possibility of a decision of normality on the FDG-PET images. The clinical diagnosis confirmed at a long-term follow-up was used as the gold standard. SPM Maps showed higher sensitivity and specificity (96% and 84%), and better diagnostic positive (6.8) and negative (0.05) likelihood ratios compared to Clinical Scenarios and Standard FDG Images. SPM Maps increased diagnostic accuracy for differential diagnosis (AD vs. FTD; beta 1.414, p = 0.019). The AUC of the ROC curve was 0.67 for SPM Maps, 0.57 for Clinical Scenarios and 0.50 for Standard FDG Images. In the MCI group, SPM Maps showed the highest predictive prognostic value (mean LOC = 2.46), by identifying either normal brain metabolism (exclusionary role) or hypometabolic patterns typical of different neurodegenerative conditions.

Published
2014
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369. Diagnostic Accuracy of Affective Social Tasks in the Clinical Classification Between the Behavioral Variant of Frontotemporal Dementia and Other Neurodegenerative Disease

Author

Alessandra Dodich, Sandro Iannaccone, Michele Zamboni, Stefano F. Cappa, Chiara Crespi, Gaia Chiara Santi, C Cerami, Valentina Ranaldi, Alessandra Marcone, and Simona Luzzi

Subjects
Male, media_common.quotation_subject, Emotions, Empathy, Neuropsychological Tests, 050105 experimental psychology, Diagnosis, Differential, Social Skills, Primary progressive aphasia, 03 medical and health sciences, 0302 clinical medicine, Basal Ganglia Diseases, Alzheimer Disease, Social cognition, medicine, Humans, 0501 psychology and cognitive sciences, Aged, media_common, Aged, 80 and over, Cerebral Cortex, Receiver operating characteristic, General Neuroscience, 05 social sciences, Neuropsychology, Cognition, General Medicine, Middle Aged, medicine.disease, Psychiatry and Mental health, Clinical Psychology, Aphasia, Primary Progressive, ROC Curve, Case-Control Studies, Frontotemporal Dementia, Female, Geriatrics and Gerontology, Psychology, Attribution, 030217 neurology & neurosurgery, Clinical psychology, Frontotemporal dementia
Abstract

Background: Severe socio-emotional impairments characterize the behavioral variant of frontotemporal dementia (bvFTD). However, literature reports social cognition disorders in other dementias. Objective: In this study, we investigated the accuracy of social cognition performances in the early and differential diagnosis of bvFTD. Methods: We included 131 subjects: 32 bvFTD, 26 Alzheimer’s disease (AD), 16 primary progressive aphasia (PPA), 17 corticobasal syndrome (CBS), and 40 healthy control (HC). Each subject completed the Ekman 60 faces (Ek-60F) test assessing basic emotion recognition and the Story-based Empathy Task (SET) assessing attribution of intentions/emotions. A combined social measure (i.e., Emotion Recognition and Attribution (ERA) index) was calculated. One-way ANOVA has been used to compare performances among groups, while receiver operating characteristic (ROC) curve tested measures ability to distinguish subjects with and without bvFTD. Results: Ek-60F and ERA index scores were significantly lower in bvFTD versus HC, AD, and PPA groups. ROC analyses significantly distinguished bvFTD from HC (AUC 0.82–0.92), with the Ek-60F test showing the highest performance, followed by the ERA index. These two social measures showed the best accuracy in detecting bvFTD from AD (AUC 0.78–0.74) and PPA (AUC 0.80–0.76). Investigated measures failed in detecting bvFTD from CBS. Conclusion: Accuracy analyses support the advantage of using social cognition tests for bvFTD diagnosis. Short social battery may reduce uncertainties and improve disease identification in clinical settings. We recommend a revision of current clinical criteria considering neuropsychological deficits in emotion recognition and processing tasks as key cognitive markers of this neurodegenerative syndrome.

Published
2021
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370. Large-Scale Functional Networks, Cognition and Brain Structures Supporting Social Cognition and Theory of Mind Performance in Prodromal to Mild Alzheimer’s Disease

Author

Jose Manuel Valera-Bermejo, Matteo De Marco, Micaela Mitolo, Chiara Cerami, Alessandra Dodich, Annalena Venneri, Valera-Bermejo J.M., De Marco M., Mitolo M., Cerami C., Dodich A., and Venneri A.

Subjects
Aging, Cognitive Neuroscience, Temporoparietal junction, fMRI, Neuropsychology, Cognition, Neurosciences. Biological psychiatry. Neuropsychiatry, social cognition, medicine.anatomical_structure, mild cognitive impairment, Social cognition, Theory of mind, medicine, Psychology, Prefrontal cortex, VBM, Insula, Alzheimer’s disease, Default mode network, Cognitive psychology, Neuroscience, Original Research, theory of mind, RC321-571
Abstract

Copyright © 2021 Valera-Bermejo, De Marco, Mitolo, Cerami, Dodich and Venneri. Impairment of social cognition (SC) skills such as recognition and attribution of intentions and affective states of others (Theory of Mind, ToM) has been evidenced in Alzheimer’s Disease (AD). This study investigated the neuropsychological, neuroanatomical and brain-functional underpinnings of SC processing to obtain an understanding of the social neurophenotype in early probable AD. Forty-six patients with mild cognitive impairment and mild probable AD underwent SC assessment including emotion recognition (Ekman-60-faces task) and cognitive and affective ToM (Reading-the-Mind-in-the-Eyes test and Story-based Empathy task). Linear models tested the association between SC scores and neuropsychological measures, grey matter maps and large-scale functional networks activity. The executive domain had the most predominant association with SC scores in the cognitive profile. Grey matter volume of the anterior cingulate, orbitofrontal, temporoparietal junction (TPJ), superior temporal, and cerebellar cortices were associated with ToM. Social cognition scores were associated with lower connectivity of the default-mode network with the prefrontal cortex. The right fronto-parietal network displayed higher inter-network connectivity in the right TPJ and insula while the salience network showed lower inter-network connectivity with the left TPJ and insula. Connectivity coupling alterations of executive-attentional networks may support default mode social-cognitive-associated decline through the recruitment of frontal executive mechanisms. European Union Seventh Framework Programme (FP7/2007 – 2013) under grant agreement no. 601055, VPH-DARE@IT; Consejo Nacional de Ciencia y Tecnología (CONACYT), Mexico.

Published
2021
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375. Circulation of respiratory viruses during the COVID-19 pandemic in The Gambia

Author

Jarju, S., primary, Senghore, E., additional, Brotherton, H., additional, Saidykhan, A., additional, Jallow, S., additional, Krubally, E., additional, Sinjanka, E., additional, Ndene, M.N., additional, Bajo, F., additional, Sanyang, M., additional, Saidy, B., additional, Bah, A, additional, Forrest, K., additional, Clarke, E., additional, D’Alessandro, U., additional, Usuf, E., additional, Cerami, C., additional, Roca, A., additional, Kampmann, B., additional, and de Silva, T. I., additional

Published
2022
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376. Predicting attitudinal and behavioral responses to COVID-19 pandemic using machine learning

Author

Pavlović, Tomislav, primary, Azevedo, Flavio, additional, De, Koustav, additional, Riaño-Moreno, Julián C, additional, Maglić, Marina, additional, Gkinopoulos, Theofilos, additional, Donnelly-Kehoe, Patricio Andreas, additional, Payán-Gómez, César, additional, Huang, Guanxiong, additional, Kantorowicz, Jaroslaw, additional, Birtel, Michèle D, additional, Schönegger, Philipp, additional, Capraro, Valerio, additional, Santamaría-García, Hernando, additional, Yucel, Meltem, additional, Ibanez, Agustin, additional, Rathje, Steve, additional, Wetter, Erik, additional, Stanojević, Dragan, additional, van Prooijen, Jan-Willem, additional, Hesse, Eugenia, additional, Elbaek, Christian T, additional, Franc, Renata, additional, Pavlović, Zoran, additional, Mitkidis, Panagiotis, additional, Cichocka, Aleksandra, additional, Gelfand, Michele, additional, Alfano, Mark, additional, Ross, Robert M, additional, Sjåstad, Hallgeir, additional, Nezlek, John B, additional, Cislak, Aleksandra, additional, Lockwood, Patricia, additional, Abts, Koen, additional, Agadullina, Elena, additional, Amodio, David M, additional, Apps, Matthew A J, additional, Aruta, John Jamir Benzon, additional, Besharati, Sahba, additional, Bor, Alexander, additional, Choma, Becky, additional, Cunningham, William, additional, Ejaz, Waqas, additional, Farmer, Harry, additional, Findor, Andrej, additional, Gjoneska, Biljana, additional, Gualda, Estrella, additional, Huynh, Toan L D, additional, Imran, Mostak Ahamed, additional, Israelashvili, Jacob, additional, Kantorowicz-Reznichenko, Elena, additional, Krouwel, André, additional, Kutiyski, Yordan, additional, Laakasuo, Michael, additional, Lamm, Claus, additional, Levy, Jonathan, additional, Leygue, Caroline, additional, Lin, Ming-Jen, additional, Mansoor, Mohammad Sabbir, additional, Marie, Antoine, additional, Mayiwar, Lewend, additional, Mazepus, Honorata, additional, McHugh, Cillian, additional, Olsson, Andreas, additional, Otterbring, Tobias, additional, Packer, Dominic, additional, Palomäki, Jussi, additional, Perry, Anat, additional, Petersen, Michael Bang, additional, Puthillam, Arathy, additional, Rothmund, Tobias, additional, Schmid, Petra C, additional, Stadelmann, David, additional, Stoica, Augustin, additional, Stoyanov, Drozdstoy, additional, Stoyanova, Kristina, additional, Tewari, Shruti, additional, Todosijević, Bojan, additional, Torgler, Benno, additional, Tsakiris, Manos, additional, Tung, Hans H, additional, Umbreș, Radu Gabriel, additional, Vanags, Edmunds, additional, Vlasceanu, Madalina, additional, Vonasch, Andrew J, additional, Zhang, Yucheng, additional, Abad, Mohcine, additional, Adler, Eli, additional, Mdarhri, Hamza Alaoui, additional, Antazo, Benedict, additional, Ay, F Ceren, additional, Ba, Mouhamadou El Hady, additional, Barbosa, Sergio, additional, Bastian, Brock, additional, Berg, Anton, additional, Białek, Michał, additional, Bilancini, Ennio, additional, Bogatyreva, Natalia, additional, Boncinelli, Leonardo, additional, Booth, Jonathan E, additional, Borau, Sylvie, additional, Buchel, Ondrej, additional, de Carvalho, Chrissie Ferreira, additional, Celadin, Tatiana, additional, Cerami, Chiara, additional, Chalise, Hom Nath, additional, Cheng, Xiaojun, additional, Cian, Luca, additional, Cockcroft, Kate, additional, Conway, Jane, additional, Córdoba-Delgado, Mateo A, additional, Crespi, Chiara, additional, Crouzevialle, Marie, additional, Cutler, Jo, additional, Cypryańska, Marzena, additional, Dabrowska, Justyna, additional, Davis, Victoria H, additional, Minda, John Paul, additional, Dayley, Pamala N, additional, Delouvée, Sylvain, additional, Denkovski, Ognjan, additional, Dezecache, Guillaume, additional, Dhaliwal, Nathan A, additional, Diato, Alelie, additional, Paolo, Roberto Di, additional, Dulleck, Uwe, additional, Ekmanis, Jānis, additional, Etienne, Tom W, additional, Farhana, Hapsa Hossain, additional, Farkhari, Fahima, additional, Fidanovski, Kristijan, additional, Flew, Terry, additional, Fraser, Shona, additional, Frempong, Raymond Boadi, additional, Fugelsang, Jonathan, additional, Gale, Jessica, additional, García-Navarro, E Begoña, additional, Garladinne, Prasad, additional, Gray, Kurt, additional, Griffin, Siobhán M, additional, Gronfeldt, Bjarki, additional, Gruber, June, additional, Halperin, Eran, additional, Herzon, Volo, additional, Hruška, Matej, additional, Hudecek, Matthias F C, additional, Isler, Ozan, additional, Jangard, Simon, additional, Jørgensen, Frederik, additional, Keudel, Oleksandra, additional, Koppel, Lina, additional, Koverola, Mika, additional, Kunnari, Anton, additional, Leota, Josh, additional, Lermer, Eva, additional, Li, Chunyun, additional, Longoni, Chiara, additional, McCashin, Darragh, additional, Mikloušić, Igor, additional, Molina-Paredes, Juliana, additional, Monroy-Fonseca, César, additional, Morales-Marente, Elena, additional, Moreau, David, additional, Muda, Rafał, additional, Myer, Annalisa, additional, Nash, Kyle, additional, Nitschke, Jonas P, additional, Nurse, Matthew S, additional, de Mello, Victoria Oldemburgo, additional, Palacios-Galvez, M Soledad, additional, Pan, Yafeng, additional, Papp, Zsófia, additional, Pärnamets, Philip, additional, Paruzel-Czachura, Mariola, additional, Perander, Silva, additional, Pitman, Michael, additional, Raza, Ali, additional, Rêgo, Gabriel Gaudencio, additional, Robertson, Claire, additional, Rodríguez-Pascual, Iván, additional, Saikkonen, Teemu, additional, Salvador-Ginez, Octavio, additional, Sampaio, Waldir M, additional, Santi, Gaia Chiara, additional, Schultner, David, additional, Schutte, Enid, additional, Scott, Andy, additional, Skali, Ahmed, additional, Stefaniak, Anna, additional, Sternisko, Anni, additional, Strickland, Brent, additional, Thomas, Jeffrey P, additional, Tinghög, Gustav, additional, Traast, Iris J, additional, Tucciarelli, Raffaele, additional, Tyrala, Michael, additional, Ungson, Nick D, additional, Uysal, Mete Sefa, additional, Van Rooy, Dirk, additional, Västfjäll, Daniel, additional, Vieira, Joana B, additional, von Sikorski, Christian, additional, Walker, Alexander C, additional, Watermeyer, Jennifer, additional, Willardt, Robin, additional, Wohl, Michael J A, additional, Wójcik, Adrian Dominik, additional, Wu, Kaidi, additional, Yamada, Yuki, additional, Yilmaz, Onurcan, additional, Yogeeswaran, Kumar, additional, Ziemer, Carolin-Theresa, additional, Zwaan, Rolf A, additional, Boggio, Paulo Sergio, additional, Whillans, Ashley, additional, Van Lange, Paul A M, additional, Prasad, Rajib, additional, Onderco, Michal, additional, O'Madagain, Cathal, additional, Nesh-Nash, Tarik, additional, Laguna, Oscar Moreda, additional, Kubin, Emily, additional, Gümren, Mert, additional, Fenwick, Ali, additional, Ertan, Arhan S, additional, Bernstein, Michael J, additional, Amara, Hanane, additional, and Van Bavel, Jay Joseph, additional

Published
2022
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377. The Somatic Genomic Landscape of Glioblastoma

Author

Benz, Christopher, Barnholtz-Sloan, Jill, Barrett, Wendi, Ostrom, Quinn, Wolinsky, Yingli, Black, Keith L., Bose, Bikash, Boulos, Paul T., Boulos, Madgy, Brown, Jenn, Czerinski, Christine, Eppley, Matthew, Iacocca, Mary, Kempista, Thelma, Kitko, Teresa, Koyfman, Yakov, Rabeno, Brenda, Rastogi, Pawan, Sugarman, Michael, Swanson, Patricia, Yalamanchii, Kennedy, Otey, Ilana P., Liu, Yingchun Spring, Xiao, Yonghong, Auman, J.Todd, Chen, Peng-Chieh, Hadjipanayis, Angela, Lee, Eunjung, Lee, Semin, Park, Peter J., Seidman, Jonathan, Yang, Lixing, Kucherlapati, Raju, Kalkanis, Steven, Mikkelsen, Tom, Poisson, Laila M., Raghunathan, Aditya, Scarpace, Lisa, Bernard, Brady, Bressler, Ryan, Eakin, Andrea, Iype, Lisa, Kreisberg, Richard B., Leinonen, Kalle, Reynolds, Sheila, Rovira, Hector, Thorsson, Vesteinn, Shmulevich, Ilya, Annala, Matti J., Penny, Robert, Paulauskis, Joseph, Curley, Erin, Hatfield, Martha, Mallery, David, Morris, Scott, Shelton, Troy, Shelton, Candace, Sherman, Mark, Yena, Peggy, Cuppini, Lucia, DiMeco, Francesco, Eoli, Marica, Finocchiaro, Gaetano, Maderna, Emanuela, Pollo, Bianca, Saini, Marco, Balu, Saianand, Hoadley, Katherine A., Li, Ling, Miller, C. Ryan, Shi, Yan, Topal, Michael D., Wu, Junyuan, Dunn, Gavin, Giannini, Caterina, O'Neill, Brian P., Aksoy, B. Arman, Antipin, Yevgeniy, Borsu, Laetitia, Berman, Samuel H., Brennan, Cameron W., Cerami, Ethan, Chakravarty, Debyani, Ciriello, Giovanni, Gao, Jianjiong, Gross, Benjamin, Jacobsen, Anders, Ladanyi, Marc, Lash, Alex, Liang, Yupu, Reva, Boris, Sander, Chris, Schultz, Nikolaus, Shen, Ronglai, Socci, Nicholas D., Viale, Agnes, Ferguson, Martin L., Chen, Qing-Rong, Demchok, John A., Dillon, Laura A.L., Shaw, Kenna R. Mills, Sheth, Margi, Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Davidsen, Tanja, Guyer, Mark S., Ozenberger, Bradley A., Sofia, Heidi J., Bergsten, Julie, Eckman, John, Harr, Jodi, Myers, Jerome, Smith, Christine, Tucker, Kelly, Winemiller, Cindy, Zach, Leigh Anne, Ljubimova, Julia Y., Eley, Greg, Ayala, Brenda, Jensen, Mark A., Kahn, Ari, Pihl, Todd D., Pot, David A., Wan, Yunhu, Eschbacher, Jennifer, Foltz, Greg, Hansen, Nathan, Hothi, Parvi, Lin, Biaoyang, Shah, Nameeta, Yoon, Jae-geun, Lau, Ching, Berens, Michael, Ardlie, Kristin, Beroukhim, Rameen, Carter, Scott L., Cherniack, Andrew D., Noble, Mike, Cho, Juok, Cibulskis, Kristian, DiCara, Daniel, Frazer, Scott, Gabriel, Stacey B., Gehlenborg, Nils, Gentry, Jeff, Heiman, David, Kim, Jaegil, Jing, Rui, Lander, Eric S., Lawrence, Michael, Lin, Pei, Mallard, Will, Meyerson, Matthew, Onofrio, Robert C., Saksena, Gordon, Schumacher, Steve, Sougnez, Carrie, Stojanov, Petar, Tabak, Barbara, Voet, Doug, Zhang, Hailei, Zou, Lihua, Getz, Gad, Dees, Nathan N., Ding, Li, Fulton, Lucinda L., Fulton, Robert S., Kanchi, Krishna-Latha, Mardis, Elaine R., Wilson, Richard K., Baylin, Stephen B., Andrews, David W., Harshyne, Larry, Cohen, Mark L., Devine, Karen, Sloan, Andrew E., VandenBerg, Scott R., Berger, Mitchel S., Prados, Michael, Carlin, Daniel, Craft, Brian, Ellrott, Kyle, Goldman, Mary, Goldstein, Theodore, Grifford, Mia, Haussler, David, Ma, Singer, Ng, Sam, Salama, Sofie R., Sanborn, J. Zachary, Stuart, Joshua, Swatloski, Teresa, Waltman, Peter, Zhu, Jing, Foss, Robin, Frentzen, Barbara, Friedman, William, McTiernan, Raquel, Yachnis, Anthony, Hayes, D. Neil, Perou, Charles M., Zheng, Siyuan, Vegesna, Rahulsimham, Mao, Yong, Akbani, Rehan, Aldape, Kenneth, Bogler, Oliver, Fuller, Gregory N., Liu, Wenbin, Liu, Yuexin, Lu, Yiling, Mills, Gordon, Protopopov, Alexei, Ren, Xiaojia, Sun, Youting, Wu, Chang-Jiun, Yung, W.K. Alfred, Zhang, Wei, Zhang, Jianhua, Chen, Ken, Weinstein, John N., Chin, Lynda, Verhaak, Roel G.W., Noushmehr, Houtan, Weisenberger, Daniel J., Bootwalla, Moiz S., Lai, Phillip H., Triche, Timothy J., Jr., Van Den Berg, David J., Laird, Peter W., Gutmann, David H., Lehman, Norman L., VanMeir, Erwin G., Brat, Daniel, Olson, Jeffrey J., Mastrogianakis, Gena M., Devi, Narra S., Zhang, Zhaobin, Bigner, Darell, Lipp, Eric, McLendon, Roger, McKenna, Aaron, Campos, Benito, Genovese, Giannicola, Shukla, Sachet A., Yung, W.K., Bigner, Darell D., Van Meir, Erwin G., Sloan, Andrew, Guha, Abhijit, O’Neill, Brian P., Gibbs, Richard, Marra, Marco, Mills, Gordon B., Lander, Eric, Spellman, Paul, Wilson, Richard, Weinstein, John, and Gabriel, Stacey

Published
2013
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379. Autosomal Dominant Frontotemporal Lobar Degeneration Due to the C9ORF72 Hexanucleotide Repeat Expansion: Late-Onset Psychotic Clinical Presentation

Author

Galimberti, Daniela, Fenoglio, Chiara, Serpente, Maria, Villa, Chiara, Bonsi, Rossana, Arighi, Andrea, Fumagalli, Giorgio G., Del Bo, Roberto, Bruni, Amalia C., Anfossi, Maria, Clodomiro, Alessandra, Cupidi, Chiara, Nacmias, Benedetta, Sorbi, Sandro, Piaceri, Irene, Bagnoli, Silvia, Bessi, Valentina, Marcone, Alessandra, Cerami, Chiara, Cappa, Stefano F., Filippi, Massimo, Agosta, Federica, Magnani, Giuseppe, Comi, Giancarlo, Franceschi, Massimo, Rainero, Innocenzo, Giordana, Maria Teresa, Rubino, Elisa, Ferrero, Patrizia, Rogaeva, Ekaterina, Xi, Zhengrui, Confaloni, Annamaria, Piscopo, Paola, Bruno, Giuseppe, Talarico, Giuseppina, Cagnin, Annachiara, Clerici, Francesca, Dell’Osso, Bernardo, Comi, Giacomo P., Altamura, A. Carlo, Mariani, Claudio, and Scarpini, Elio

Published
2013
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380. 11C-PK11195 PET–based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis

Author

Tondo, G, Iaccarino, L, Cerami, C, Vanoli, G, Presotto, L, Masiello, V, Coliva, A, Salvi, F, Bartolomei, I, Mosca, L, Lunetta, C, Perani, D, Tondo G., Iaccarino L., Cerami C., Vanoli G. E., Presotto L., Masiello V., Coliva A., Salvi F., Bartolomei I., Mosca L., Lunetta C., Perani D., Tondo, G, Iaccarino, L, Cerami, C, Vanoli, G, Presotto, L, Masiello, V, Coliva, A, Salvi, F, Bartolomei, I, Mosca, L, Lunetta, C, Perani, D, Tondo G., Iaccarino L., Cerami C., Vanoli G. E., Presotto L., Masiello V., Coliva A., Salvi F., Bartolomei I., Mosca L., Lunetta C., and Perani D.

Abstract

Objective: Neuroinflammation is considered a key driver for neurodegeneration in several neurological diseases, including amyotrophic lateral sclerosis (ALS). SOD1 mutations cause about 20% of familial ALS, and related pathology might generate microglial activation triggering neurodegeneration. 11C-PK11195 is the prototypical and most validated PET radiotracer, targeting the 18-kDa translocator protein which is overexpressed in activated microglia. In this study, we investigated microglia activation in asymptomatic (ASYM) and symptomatic (SYM) SOD1 mutated carriers, by using 11C-PK11195 and PET imaging. Methods: We included 20 subjects: 4 ASYM-carriers, neurologically normal, 6 SYM-carriers with probable ALS, and 10 healthy controls. A receptor parametric mapping procedure estimated 11C-PK11195 binding potentials and voxel-wise statistical comparisons were performed at group and single-subject levels. Results: Both the SYM- and ASYM-carriers showed significant microglia activation in cortical and subcortical structures, with variable patterns at individual level. Clusters of activation were present in occipital and temporal regions, cerebellum, thalamus, and medulla oblongata. Notably, SYM-carriers showed microglia activation also in supplementary and primary motor cortices and in the somatosensory regions. Interpretation: In vivo neuroinflammation occurred in all SOD1 mutated cases since the presymptomatic stages, as shown by a significant cortical and subcortical microglia activation. The involvement of sensorimotor cortex became evident at the symptomatic disease stage. Although our data indicate the role of in vivo PET imaging for assessing resident microglia in the investigation of SOD1-ALS pathophysiology, further studies are needed to clarify the temporal and spatial dynamics of microglia activation and its relationship with neurodegeneration.

Published
2020

383. Abstract 5706: ImmunoPROFILE: A prospective implementation of clinically validated, quantitative immune cell profiling test identifies tumor-infiltrating CD8+ and PD-1+ cell densities as prognostic biomarkers across a 2,023 patient pan-cancer cohort treated with different therapies

Author

James Lindsay, Bijaya Sharma, Kristen D. Felt, Anita Giobbie-Hurder, Ian Dryg, Jason L. Weirather, Jennifer Altreuter, Tali Mazor, Priti Kumari, Joao V. Alessi, Ajit J. Nirmal, Michael P. Manos, Ananth R. Kumar, William Lotter, Ethan Cerami, Burce E. Johnson, Neil I. Lindeman, Lynette M. Sholl, Jonathan A. Nowak, and Scott J. Rodig

Subjects
Cancer Research, Oncology
Abstract

Tumor-infiltrating lymphocyte (TIL) density has been identified as a prognostic and predictive biomarker in select tumors treated with defined therapies. These observations suggest that TILs may be general markers of patient outcomes, but evidence in support of this hypothesis has been limited by small cohorts. We validated ImmunoPROFILE, a multiplexed immunofluorescence (MIF)-based assay coupled with machine-learning-based image analysis, to identify and quantify tumor cells (cytokeratin, PAX5, PAX8, SOX10), T cells (CD8), T-regulatory cells (FOXP3), exhausted cells (PD-1) and immunosuppressive tumor and immune cells (PD-L1). We applied the MIF panel to specimens from patients collected prospectively over three years and analyzed 2,023 cases across 27 tumor types. The association between biomarkers and overall survival (OS) was investigated using Cox models controlling for patient risk factors such as cancer type, metastatic vs. primary disease, age, and gender. Multivariable biomarker selection was based on likelihood ratios. The assay was highly robust (success rate 97%), reproducible (inter-scanning and intra-staining density controls within 1 SD, inter-staining PD-L1 scores ≤11% CV), and operator-independent (R2 >0.7 to >0.9 for each biomarker and 95% concordance in PD-L1 score-based interpretation between technicians). From whole slide images, a total of 11,932 individual regions of interest were analyzed across the cohort, resulting in >50 million spatially-resolved single cells which were summarized into cell population densities and PD-L1 scores. High densities of CD8+ (>64/mm2, p50/mm2, p30/mm2, p To our knowledge, this is the first enterprise-level immune biomarker assay using multiplexed staining, digital imaging, and machine learning to be applied in a prospective manner to clinical specimens at scale. We found that select immune cell densities are prognostic across cancer types and therapies and demonstrated that quantification of multiple cell populations yields better prognostic power than single marker analyses. Citation Format: James Lindsay, Bijaya Sharma, Kristen D. Felt, Anita Giobbie-Hurder, Ian Dryg, Jason L. Weirather, Jennifer Altreuter, Tali Mazor, Priti Kumari, Joao V. Alessi, Ajit J. Nirmal, Michael P. Manos, Ananth R. Kumar, William Lotter, Ethan Cerami, Burce E. Johnson, Neil I. Lindeman, Lynette M. Sholl, Jonathan A. Nowak, Scott J. Rodig. ImmunoPROFILE: A prospective implementation of clinically validated, quantitative immune cell profiling test identifies tumor-infiltrating CD8+ and PD-1+ cell densities as prognostic biomarkers across a 2,023 patient pan-cancer cohort treated with different therapies. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5706.

Published
2023
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384. Abstract 4256: cBioPortal for Cancer Genomics

Author

Ino de Bruijn, Tali Mazor, Adam Abeshouse, Diana Baiceanu, Stephanie Carrero, Elena Garcia Lara, Benjamin Gross, David M. Higgins, Prasanna K. Jagannathan, Priti Kumari, Ritika Kundra, Bryan Lai, Xiang Li, James Lindsay, Aaron Lisman, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Yusuf Ziya Özgül, Oleguer Plantalech, Sander Rodenburg, Baby Anusha Satravada, Robert Sheridan, Lucas Sikina, Jessica Singh, S Onur Sumer, Yichao Sun, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, and Nikolaus Schultz

Subjects
Cancer Research, Oncology
Abstract

cBioPortal for Cancer Genomics is an open-source platform for interactive, exploratory analysis of large-scale clinico-genomic data sets. cBioPortal provides a suite of user-friendly visualizations and analyses, including OncoPrints, mutation “lollipop” plots, variant interpretation, group comparison, survival analysis, expression correlation analysis, alteration enrichment analysis, cohort and patient-level visualization. The public site (https://www.cbioportal.org) is accessed by >35,000 unique visitors each month and hosts data from >350 studies spanning individual labs and large consortia. In addition, at least 74 instances of cBioPortal are installed at academic institutions and companies worldwide. To better support all users, we unified our documentation (https://docs.cbioportal.org) and added a user guide and an ongoing series of ‘how-to’ videos to address common questions. In 2022 we added 32 studies (>38,000 samples) to the public site. In addition, we added a nonsynonymous tumor mutation burden (TMB) value for all samples and enhanced the TCGA PanCancer Atlas studies with DNA methylation and treatment data. All data is available in the cBioPortal Datahub: https://github.com/cBioPortal/datahub. We also host a dedicated instance for AACR Project GENIE, enabling access to the GENIE cohort of >165,000 clinically sequenced samples from 19 institutions (https://genie.cbioportal.org). The GENIE Biopharma Collaborative (BPC) enables the collection of comprehensive clinical annotations, including response, outcome, and treatment history. The first BPC cohorts are now available: ~2,000 non-small cell lung cancer samples and ~1,500 colorectal cancer samples. Support for multimodal data analysis has been a major focus, including several new integrations with external tools. Single cell data is now available in the CPTAC GBM study and can be visualized throughout cBioPortal, and via integration with cellxgene. On the patient page, H&E and mIF images can be visualized via integration with Minerva, and the genomic overview now integrates IGV. We continue to enhance existing features. In the study view, users can now add charts comparing categorical vs continuous data, and the plots tab includes a heatmap option. We replaced the existing fusion data type with a generalized structural variant data type that supports detailed information including breakpoints and orientation, to enable new visualizations and analyses. Pathway level analysis has been extended with a new integration with NDEx. cBioPortal is fully open source (https://github.com/cBioPortal/). Development is a collaborative effort among groups at Memorial Sloan Kettering Cancer Center, Dana-Farber Cancer Institute, Children’s Hospital of Philadelphia, Princess Margaret Cancer Centre, Caris Life Sciences, Bilkent University and The Hyve. We welcome open source contributions from others in the cancer research community. Citation Format: Ino de Bruijn, Tali Mazor, Adam Abeshouse, Diana Baiceanu, Stephanie Carrero, Elena Garcia Lara, Benjamin Gross, David M. Higgins, Prasanna K. Jagannathan, Priti Kumari, Ritika Kundra, Bryan Lai, Xiang Li, James Lindsay, Aaron Lisman, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Yusuf Ziya Özgül, Oleguer Plantalech, Sander Rodenburg, Baby Anusha Satravada, Robert Sheridan, Lucas Sikina, Jessica Singh, S Onur Sumer, Yichao Sun, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, Nikolaus Schultz. cBioPortal for Cancer Genomics. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4256.

Published
2023
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386. Genomic Characterization of de novo Metastatic Breast Cancer

Author

Ethan Cerami, Daniel Xia, Maxwell R. Lloyd, William T. Barry, Ian E. Krop, Nan Lin, Priti Kumari, Barrett J. Rollins, Yvonne Y. Li, Simona Di Lascio, Eric P. Winer, Andrew D. Cherniack, Romualdo Barroso-Sousa, Deborah A. Dillon, Ayesha Mohammed-Abreu, Nikhil Wagle, Colin Mackichan, Janet Files, Liam F. Spurr, Laura E. MacConaill, Bruce E. Johnson, Hao Guo, Max Krevalin, Brittany L. Bychkovsky, Esha Jain, Ana C. Garrido-Castro, Melissa E. Hughes, and Neal I. Lindeman

Subjects
0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, business.industry, Intrinsic resistance, medicine.disease, Metastatic breast cancer, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Breast cancer, Text mining, SETD2, 030220 oncology & carcinogenesis, Internal medicine, medicine, In patient, Stage (cooking), business, Gene
Abstract

Purpose: In contrast to recurrence after initial diagnosis of stage I–III breast cancer [recurrent metastatic breast cancer (rMBC)], de novo metastatic breast cancer (dnMBC) represents a unique setting to elucidate metastatic drivers in the absence of treatment selection. We present the genomic landscape of dnMBC and association with overall survival (OS). Experimental Design: Targeted DNA sequencing (OncoPanel) was prospectively performed on either primary or metastatic tumors from 926 patients (212 dnMBC and 714 rMBC). Single-nucleotide variants, copy-number variations, and tumor mutational burden (TMB) in treatment-naïve dnMBC primary tumors were compared with primary tumors in patients who ultimately developed rMBC, and correlated with OS across all dnMBC. Results: When comparing primary tumors by subtype, MYB amplification was enriched in triple-negative dnMBC versus rMBC (21.1% vs. 0%, P = 0.0005, q = 0.111). Mutations in KMTD2, SETD2, and PIK3CA were more prevalent, and TP53 and BRCA1 less prevalent, in primary HR+/HER2− tumors of dnMBC versus rMBC, though not significant after multiple comparison adjustment. Alterations associated with shorter OS in dnMBC included TP53 (wild-type: 79.7 months; altered: 44.2 months; P = 0.008, q = 0.107), MYC (79.7 vs. 23.3 months; P = 0.0003, q = 0.011), and cell-cycle (122.7 vs. 54.9 months; P = 0.034, q = 0.245) pathway genes. High TMB correlated with better OS in triple-negative dnMBC (P = 0.041). Conclusions: Genomic differences between treatment-naïve dnMBC and primary tumors of patients who developed rMBC may provide insight into mechanisms underlying metastatic potential and differential therapeutic sensitivity in dnMBC. Alterations associated with poor OS in dnMBC highlight the need for novel approaches to overcome potential intrinsic resistance to current treatments.

Published
2021
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389. National identity predicts public health support during a global pandemic (vol 13, 517, 2022) : National identity predicts public health support during a global pandemic (Nature Communications, (2022), 13, 1, (517), 10.1038/s41467-021-27668-9)

Author

Van Bavel, Jay J., Cichocka, Aleksandra, Capraro, Valerio, Sjåstad, Hallgeir, Nezlek, John B., Pavlović, Tomislav, Alfano, Mark, Gelfand, Michele J., Azevedo, Flavio, Birtel, Michèle D., Cislak, Aleksandra, Lockwood, Patricia L., Ross, Robert Malcolm, Abts, Koen, Agadullina, Elena, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Crabtree, Charles David, Cunningham, William A., De, Koustav, Ejaz, Waqas, Elbaek, Christian T., Findor, Andrej, Flichtentrei, Daniel, Franc, Renata, Gjoneska, Biljana, Gruber, June, Gualda, Estrella, Horiuchi, Yusaku, Huynh, Toan Luu Duc, Ibanez, Agustin, Imran, Mostak Ahamed, Israelashvili, Jacob, Jasko, Katarzyna, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Krouwel, André, Laakasuo, Michael, Lamm, Claus, Leygue, Caroline, Lin, Ming Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Minda, John Paul, Mitkidis, Panagiotis, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Riaño-Moreno, Julián C., Rothmund, Tobias, Santamaría-García, Hernando, Schmid, Petra C., Stoyanov, Drozdstoy, Tewari, Shruti, Todosijević, Bojan, Tsakiris, Manos, Tung, Hans H., Umbreș, Radu G., Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew, Yucel, Meltem, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Akrawi, Narin, Mdarhri, Hamza Alaoui, Amara, Hanane, Amodio, David M., Antazo, Benedict G., Apps, Matthew, Ay, F. Ceren, Ba, Mouhamadou Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Bernal-Zárate, Maria P., Bernstein, Michael, Białek, Michał, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, Cameron, C. Daryl, Carvalho, Chrissie F., Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Córdoba-Delgado, Mateo Andres, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Cypryańska, Marzena, Dabrowska, Justyna, Daniels, Michael A., Davis, Victoria H., Dayley, Pamala N., Delouvee, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Drosinou, Marianna, Dulleck, Uwe, Ekmanis, Jānis, Ertan, Arhan S., Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Farmer, Harry, Fenwick, Ali, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, Garcia-Navarro, E. Begoña, Garladinne, Prasad, Ghajjou, Oussama, Gkinopoulos, Theofilos, Gray, Kurt, Griffin, Siobhán M., Gronfeldt, Bjarki, Gümren, Mert, Gurung, Ranju Lama, Halperin, Eran, Harris, Elizabeth, Herzon, Volo, Hruška, Matej, Huang, Guanxiong, Hudecek, Matthias F.C., Isler, Ozan, Jangard, Simon, Jørgensen, Frederik J., Kachanoff, Frank, Kahn, John, Dangol, Apsara Katuwal, Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kubin, Emily, Kunnari, Anton, Kutiyski, Yordan, Laguna, Oscar, Leota, Josh, Lermer, Eva, Levy, Jonathan, Levy, Neil, Li, Chunyun, Long, Elizabeth U., Longoni, Chiara, Maglić, Marina, McCashin, Darragh, Metcalf, Alexander L., Mikloušić, Igor, El Mimouni, Soulaimane, Miura, Asako, Molina-Paredes, Juliana, Monroy-Fonseca, César, Morales-Marente, Elena, Moreau, David, Muda, Rafał, Myer, Annalisa, Nash, Kyle, Nesh-Nash, Tarik, Nitschke, Jonas P., Nurse, Matthew S., Ohtsubo, Yohsuke, Oldemburgo de Mello, Victoria, O’Madagain, Cathal, Onderco, Michal, Palacios-Galvez, M. Soledad, Palomäki, Jussi, Pan, Yafeng, Papp, Zsófia, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlović, Zoran, Payán-Gómez, César, Perander, Silva, Pitman, Michael Mark, Prasad, Rajib, Pyrkosz-Pacyna, Joanna, Rathje, Steve, Raza, Ali, Rêgo, Gabriel G., Rhee, Kasey, Robertson, Claire E., Rodríguez-Pascual, Iván, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia C., Santiago-Tovar, Natalia, Savage, David, Scheffer, Julian A., Schönegger, Philipp, Schultner, David T., Schutte, Enid M., Scott, Andy, Sharma, Madhavi, Sharma, Pujan, Skali, Ahmed, Stadelmann, David, Stafford, Clara Alexandra, Stanojević, Dragan, Stefaniak, Anna, Sternisko, Anni, Stoica, Augustin, Stoyanova, Kristina K., Strickland, Brent, Sundvall, Jukka, Thomas, Jeffrey P., Tinghög, Gustav, Torgler, Benno, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete S., Van Lange, Paul A.M., van Prooijen, Jan Willem, van Rooy, Dirk, Västfjäll, Daniel, Verkoeijen, Peter, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander Cameron, Watermeyer, Jennifer, Wetter, Erik, Whillans, Ashley, Willardt, Robin, Wohl, Michael J.A., Wójcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin Theresa, Zwaan, Rolf A., Boggio, Paulo S., Berg, Niko Anton, Department of Digital Humanities, University of Helsinki, Faculty Common Matters (Faculty of Arts), Department of Psychology and Logopedics, Cognitive Science, Doctoral Programme in Theology and Religious Studies, Helsinki Social Computing Group, Helsinki Institute for Social Sciences and Humanities (HSSH), Doctoral Programme in Cognition, Learning, Instruction and Communication, Doctoral Programme Brain & Mind, Mind and Matter, High Performance Cognition group, Department of Biochemistry and Developmental Biology, Medicum, Digital Humanities, and Faculty of Theology

Subjects
5200 Other social sciences
Abstract

Publisher Copyright: © The Author(s) 2022. In this article the author name ‘Agustin Ibanez’ was incorrectly written as ‘Augustin Ibanez’. The original article has been corrected.

Published
2022

390. Author Correction: National identity predicts public health support during a global pandemic

Author

Jay J. Van Bavel, Aleksandra Cichocka, Valerio Capraro, Hallgeir Sjåstad, John B. Nezlek, Tomislav Pavlović, Mark Alfano, Michele J. Gelfand, Flavio Azevedo, Michèle D. Birtel, Aleksandra Cislak, Patricia L. Lockwood, Robert Malcolm Ross, Koen Abts, Elena Agadullina, John Jamir Benzon Aruta, Sahba Nomvula Besharati, Alexander Bor, Becky L. Choma, Charles David Crabtree, William A. Cunningham, Koustav De, Waqas Ejaz, Christian T. Elbaek, Andrej Findor, Daniel Flichtentrei, Renata Franc, Biljana Gjoneska, June Gruber, Estrella Gualda, Yusaku Horiuchi, Toan Luu Duc Huynh, Agustin Ibanez, Mostak Ahamed Imran, Jacob Israelashvili, Katarzyna Jasko, Jaroslaw Kantorowicz, Elena Kantorowicz-Reznichenko, André Krouwel, Michael Laakasuo, Claus Lamm, Caroline Leygue, Ming-Jen Lin, Mohammad Sabbir Mansoor, Antoine Marie, Lewend Mayiwar, Honorata Mazepus, Cillian McHugh, John Paul Minda, Panagiotis Mitkidis, Andreas Olsson, Tobias Otterbring, Dominic J. Packer, Anat Perry, Michael Bang Petersen, Arathy Puthillam, Julián C. Riaño-Moreno, Tobias Rothmund, Hernando Santamaría-García, Petra C. Schmid, Drozdstoy Stoyanov, Shruti Tewari, Bojan Todosijević, Manos Tsakiris, Hans H. Tung, Radu G. Umbreș, Edmunds Vanags, Madalina Vlasceanu, Andrew Vonasch, Meltem Yucel, Yucheng Zhang, Mohcine Abad, Eli Adler, Narin Akrawi, Hamza Alaoui Mdarhri, Hanane Amara, David M. Amodio, Benedict G. Antazo, Matthew Apps, F. Ceren Ay, Mouhamadou Hady Ba, Sergio Barbosa, Brock Bastian, Anton Berg, Maria P. Bernal-Zárate, Michael Bernstein, Michał Białek, Ennio Bilancini, Natalia Bogatyreva, Leonardo Boncinelli, Jonathan E. Booth, Sylvie Borau, Ondrej Buchel, C. Daryl Cameron, Chrissie F. Carvalho, Tatiana Celadin, Chiara Cerami, Hom Nath Chalise, Xiaojun Cheng, Luca Cian, Kate Cockcroft, Jane Conway, Mateo Andres Córdoba-Delgado, Chiara Crespi, Marie Crouzevialle, Jo Cutler, Marzena Cypryańska, Justyna Dabrowska, Michael A. Daniels, Victoria H. Davis, Pamala N. Dayley, Sylvain Delouvee, Ognjan Denkovski, Guillaume Dezecache, Nathan A. Dhaliwal, Alelie B. Diato, Roberto Di Paolo, Marianna Drosinou, Uwe Dulleck, Jānis Ekmanis, Arhan S. Ertan, Tom W. Etienne, Hapsa Hossain Farhana, Fahima Farkhari, Harry Farmer, Ali Fenwick, Kristijan Fidanovski, Terry Flew, Shona Fraser, Raymond Boadi Frempong, Jonathan A. Fugelsang, Jessica Gale, E. Begoña Garcia-Navarro, Prasad Garladinne, Oussama Ghajjou, Theofilos Gkinopoulos, Kurt Gray, Siobhán M. Griffin, Bjarki Gronfeldt, Mert Gümren, Ranju Lama Gurung, Eran Halperin, Elizabeth Harris, Volo Herzon, Matej Hruška, Guanxiong Huang, Matthias F. C. Hudecek, Ozan Isler, Simon Jangard, Frederik J. Jørgensen, Frank Kachanoff, John Kahn, Apsara Katuwal Dangol, Oleksandra Keudel, Lina Koppel, Mika Koverola, Emily Kubin, Anton Kunnari, Yordan Kutiyski, Oscar Laguna, Josh Leota, Eva Lermer, Jonathan Levy, Neil Levy, Chunyun Li, Elizabeth U. Long, Chiara Longoni, Marina Maglić, Darragh McCashin, Alexander L. Metcalf, Igor Mikloušić, Soulaimane El Mimouni, Asako Miura, Juliana Molina-Paredes, César Monroy-Fonseca, Elena Morales-Marente, David Moreau, Rafał Muda, Annalisa Myer, Kyle Nash, Tarik Nesh-Nash, Jonas P. Nitschke, Matthew S. Nurse, Yohsuke Ohtsubo, Victoria Oldemburgo de Mello, Cathal O’Madagain, Michal Onderco, M. Soledad Palacios-Galvez, Jussi Palomäki, Yafeng Pan, Zsófia Papp, Philip Pärnamets, Mariola Paruzel-Czachura, Zoran Pavlović, César Payán-Gómez, Silva Perander, Michael Mark Pitman, Rajib Prasad, Joanna Pyrkosz-Pacyna, Steve Rathje, Ali Raza, Gabriel G. Rêgo, Kasey Rhee, Claire E. Robertson, Iván Rodríguez-Pascual, Teemu Saikkonen, Octavio Salvador-Ginez, Waldir M. Sampaio, Gaia C. Santi, Natalia Santiago-Tovar, David Savage, Julian A. Scheffer, Philipp Schönegger, David T. Schultner, Enid M. Schutte, Andy Scott, Madhavi Sharma, Pujan Sharma, Ahmed Skali, David Stadelmann, Clara Alexandra Stafford, Dragan Stanojević, Anna Stefaniak, Anni Sternisko, Augustin Stoica, Kristina K. Stoyanova, Brent Strickland, Jukka Sundvall, Jeffrey P. Thomas, Gustav Tinghög, Benno Torgler, Iris J. Traast, Raffaele Tucciarelli, Michael Tyrala, Nick D. Ungson, Mete S. Uysal, Paul A. M. Van Lange, Jan-Willem van Prooijen, Dirk van Rooy, Daniel Västfjäll, Peter Verkoeijen, Joana B. Vieira, Christian von Sikorski, Alexander Cameron Walker, Jennifer Watermeyer, Erik Wetter, Ashley Whillans, Robin Willardt, Michael J. A. Wohl, Adrian Dominik Wójcik, Kaidi Wu, Yuki Yamada, Onurcan Yilmaz, Kumar Yogeeswaran, Carolin-Theresa Ziemer, Rolf A. Zwaan, and Paulo S. Boggio

Subjects
Multidisciplinary, General Physics and Astronomy, General Chemistry, Q1, General Biochemistry, Genetics and Molecular Biology
Abstract

In this article the author name ‘Agustin Ibanez’ was incorrectly written as ‘Augustin Ibanez’. The original article has been corrected.

Published
2022
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391. 11 C‐PK11195 PET–based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis

Author

Ilaria Bartolomei, Christian Lunetta, Leonardo Iaccarino, Fabrizio Salvi, Chiara Cerami, Daniela Perani, Lorena Mosca, Giovanna Vanoli, Angela Coliva, Giacomo Tondo, Luca Presotto, Valeria Masiello, Tondo, Giacomo, Iaccarino, Leonardo, Cerami, Chiara, Vanoli, Giovanna Emilia, Presotto, Luca, Masiello, Valeria, Coliva, Angela, Salvi, Fabrizio, Bartolomei, Ilaria, Mosca, Lorena, Lunetta, Christian, Perani, Daniela, Tondo, G, Iaccarino, L, Cerami, C, Vanoli, G, Presotto, L, Masiello, V, Coliva, A, Salvi, F, Bartolomei, I, Mosca, L, Lunetta, C, and Perani, D

Subjects
0301 basic medicine, Cerebellum, SOD1, Thalamus, prion disease, Neurosciences. Biological psychiatry. Neuropsychiatry, Gene mutation, 03 medical and health sciences, 0302 clinical medicine, medicine, Amyotrophic lateral sclerosis, RC346-429, Neuroinflammation, Research Articles, Microglia, business.industry, General Neuroscience, Neurodegeneration, full quantification, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, nervous system, kinetic modelling, Neurology. Diseases of the nervous system, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery, RC321-571, Research Article
Abstract

Objective Neuroinflammation is considered a key driver for neurodegeneration in several neurological diseases, including amyotrophic lateral sclerosis (ALS). SOD1 mutations cause about 20% of familial ALS, and related pathology might generate microglial activation triggering neurodegeneration. 11 C-PK11195 is the prototypical and most validated PET radiotracer, targeting the 18-kDa translocator protein which is overexpressed in activated microglia. In this study, we investigated microglia activation in asymptomatic (ASYM) and symptomatic (SYM) SOD1 mutated carriers, by using 11 C-PK11195 and PET imaging. Methods We included 20 subjects: 4 ASYM-carriers, neurologically normal, 6 SYM-carriers with probable ALS, and 10 healthy controls. A receptor parametric mapping procedure estimated 11 C-PK11195 binding potentials and voxel-wise statistical comparisons were performed at group and single-subject levels. Results Both the SYM- and ASYM-carriers showed significant microglia activation in cortical and subcortical structures, with variable patterns at individual level. Clusters of activation were present in occipital and temporal regions, cerebellum, thalamus, and medulla oblongata. Notably, SYM-carriers showed microglia activation also in supplementary and primary motor cortices and in the somatosensory regions. Interpretation In vivo neuroinflammation occurred in all SOD1 mutated cases since the presymptomatic stages, as shown by a significant cortical and subcortical microglia activation. The involvement of sensorimotor cortex became evident at the symptomatic disease stage. Although our data indicate the role of in vivo PET imaging for assessing resident microglia in the investigation of SOD1-ALS pathophysiology, further studies are needed to clarify the temporal and spatial dynamics of microglia activation and its relationship with neurodegeneration.

Published
2020

392. National identity predicts public health support during a global pandemic

Author

Van Bavel, Jay J., Cichocka, Aleksandra, Capraro, Valerio, Sjastad, Hallgeir, Nezlek, John B., Pavlovic, Tomislav, Alfano, Mark, Gelfand, Michele J., Azevedo, Flavio, Birtel, Michele D., Cislak, Aleksandra, Lockwood, Patricia L., Ross, Robert Malcolm, Abts, Koen, Agadullina, Elena, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Crabtree, Charles David, Cunningham, William A., De, Koustav, Ejaz, Waqas, Elbaek, Christian T., Findor, Andrej, Flichtentrei, Daniel, Franc, Renata, Gjoneska, Biljana, Gruber, June, Gualda, Estrella, Horiuchi, Yusaku, Huynh, Toan Luu Duc, Ibanez, Augustin, Imran, Mostak Ahamed, Israelashvili, Jacob, Jasko, Katarzyna, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Krouwel, Andre, Laakasuo, Michael, Lamm, Claus, Leygue, Caroline, Lin, Ming-Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Minda, John Paul, Mitkidis, Panagiotis, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Riano-Moreno, Julian C., Rothmund, Tobias, Santamaria-Garcia, Hernando, Schmid, Petra C., Stoyanov, Drozdstoy, Tewari, Shruti, Todosijevic, Bojan, Tsakiris, Manos, Tung, Hans H., Umbres, Radu G., Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew, Yucel, Meltem, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Akrawi, Narin, Mdarhri, Hamza Alaoui, Amara, Hanane, Amodio, David M., Antazo, Benedict G., Apps, Matthew, Ay, F. Ceren, Ba, Mouhamadou Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Bernal-Zarate, Maria P., Bernstein, Michael, Bialek, Michal, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, Cameron, C. Daryl, Carvalho, Chrissie F., Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Andres Cordoba-Delgado, Mateo, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Dabrowska, Justyna, Cypryanska, Marzena, Daniels, Michael A., Davis, Victoria H., Dayley, Pamala N., Delouvee, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Drosinou, Marianna, Dulleck, Uwe, Ekmanis, Janis, Ertan, Arhan S., Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Farmer, Harry, Fenwick, Ali, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, Begona Garcia-Navarro, E., Garladinne, Prasad, Ghajjou, Oussama, Gkinopoulos, Theofilos, Gray, Kurt, Griffin, Siobhan M., Gronfeldt, Bjarki, Gumren, Mert, Gurung, Ranju Lama, Halperin, Eran, Harris, Elizabeth, Herzon, Volo, Hruska, Matej, Huang, Guanxiong, Hudecek, Matthias F. C., Isler, Ozan, Jangard, Simon, Jorgensen, Frederik J., Kachanoff, Frank, Kahn, John, Dangol, Apsara Katuwal, Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kubin, Emily, Kunnari, Anton, Kutiyski, Yordan, Laguna, Oscar, Leota, Josh, Lermer, Eva, Levy, Jonathan, Levy, Neil, Li, Chunyun, Long, Elizabeth U., Longoni, Chiara, Maglic, Marina, McCashin, Darragh, Metcalf, Alexander L., Miklousic, Igor, El Mimouni, Soulaimane, Miura, Asako, Molina-Paredes, Juliana, Monroy-Fonseca, Cesar, Morales-Marente, Elena, Moreau, David, Muda, Rafal, Myer, Annalisa, Nash, Kyle, Nesh-Nash, Tarik, Nitschke, Jonas P., Nurse, Matthew S., Ohtsubo, Yohsuke, de Mello, Victoria Oldemburgo, OMadagain, Cathal, Onderco, Michal, Soledad Palacios-Galvez, M., Palomaki, Jussi, Pan, Yafeng, Papp, Zsofia, Parnamets, Philip, Paruzel-Czachura, Mariola, Pavlovic, Zoran, Payan-Gomez, Cesar, Perander, Silva, Pitman, Michael Mark, Prasad, Rajib, Pyrkosz-Pacyna, Joanna, Rathje, Steve, Raza, Ali, Rego, Gabriel G., Rhee, Kasey, Robertson, Claire E., Rodriguez-Pascual, Ivan, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia C., Santiago-Tovar, Natalia, Savage, David, Scheffer, Julian A., Schonegger, Philipp, Schultner, David T., Schutte, Enid M., Scott, Andy, Sharma, Madhavi, Sharma, Pujan, Skali, Ahmed, Stadelmann, David, Stafford, Clara Alexandra, Stanojevic, Dragan, Stefaniak, Anna, Sternisko, Anni, Stoica, Augustin, Stoyanova, Kristina K., Strickland, Brent, Sundvall, Jukka, Thomas, Jeffrey P., Tinghög, Gustav, Torgler, Benno, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete S., Van Lange, Paul A. M., van Prooijen, Jan-Willem, van Rooy, Dirk, Västfjäll, Daniel, Verkoeijen, Peter, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander Cameron, Watermeyer, Jennifer, Wetter, Erik, Whillans, Ashley, Willardt, Robin, Wohl, Michael J. A., Wojcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin-Theresa, Zwaan, Rolf A., Boggio, Paulo S., Van Bavel, Jay J., Cichocka, Aleksandra, Capraro, Valerio, Sjastad, Hallgeir, Nezlek, John B., Pavlovic, Tomislav, Alfano, Mark, Gelfand, Michele J., Azevedo, Flavio, Birtel, Michele D., Cislak, Aleksandra, Lockwood, Patricia L., Ross, Robert Malcolm, Abts, Koen, Agadullina, Elena, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Crabtree, Charles David, Cunningham, William A., De, Koustav, Ejaz, Waqas, Elbaek, Christian T., Findor, Andrej, Flichtentrei, Daniel, Franc, Renata, Gjoneska, Biljana, Gruber, June, Gualda, Estrella, Horiuchi, Yusaku, Huynh, Toan Luu Duc, Ibanez, Augustin, Imran, Mostak Ahamed, Israelashvili, Jacob, Jasko, Katarzyna, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Krouwel, Andre, Laakasuo, Michael, Lamm, Claus, Leygue, Caroline, Lin, Ming-Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Minda, John Paul, Mitkidis, Panagiotis, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Riano-Moreno, Julian C., Rothmund, Tobias, Santamaria-Garcia, Hernando, Schmid, Petra C., Stoyanov, Drozdstoy, Tewari, Shruti, Todosijevic, Bojan, Tsakiris, Manos, Tung, Hans H., Umbres, Radu G., Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew, Yucel, Meltem, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Akrawi, Narin, Mdarhri, Hamza Alaoui, Amara, Hanane, Amodio, David M., Antazo, Benedict G., Apps, Matthew, Ay, F. Ceren, Ba, Mouhamadou Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Bernal-Zarate, Maria P., Bernstein, Michael, Bialek, Michal, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, Cameron, C. Daryl, Carvalho, Chrissie F., Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Andres Cordoba-Delgado, Mateo, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Dabrowska, Justyna, Cypryanska, Marzena, Daniels, Michael A., Davis, Victoria H., Dayley, Pamala N., Delouvee, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Drosinou, Marianna, Dulleck, Uwe, Ekmanis, Janis, Ertan, Arhan S., Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Farmer, Harry, Fenwick, Ali, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, Begona Garcia-Navarro, E., Garladinne, Prasad, Ghajjou, Oussama, Gkinopoulos, Theofilos, Gray, Kurt, Griffin, Siobhan M., Gronfeldt, Bjarki, Gumren, Mert, Gurung, Ranju Lama, Halperin, Eran, Harris, Elizabeth, Herzon, Volo, Hruska, Matej, Huang, Guanxiong, Hudecek, Matthias F. C., Isler, Ozan, Jangard, Simon, Jorgensen, Frederik J., Kachanoff, Frank, Kahn, John, Dangol, Apsara Katuwal, Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kubin, Emily, Kunnari, Anton, Kutiyski, Yordan, Laguna, Oscar, Leota, Josh, Lermer, Eva, Levy, Jonathan, Levy, Neil, Li, Chunyun, Long, Elizabeth U., Longoni, Chiara, Maglic, Marina, McCashin, Darragh, Metcalf, Alexander L., Miklousic, Igor, El Mimouni, Soulaimane, Miura, Asako, Molina-Paredes, Juliana, Monroy-Fonseca, Cesar, Morales-Marente, Elena, Moreau, David, Muda, Rafal, Myer, Annalisa, Nash, Kyle, Nesh-Nash, Tarik, Nitschke, Jonas P., Nurse, Matthew S., Ohtsubo, Yohsuke, de Mello, Victoria Oldemburgo, OMadagain, Cathal, Onderco, Michal, Soledad Palacios-Galvez, M., Palomaki, Jussi, Pan, Yafeng, Papp, Zsofia, Parnamets, Philip, Paruzel-Czachura, Mariola, Pavlovic, Zoran, Payan-Gomez, Cesar, Perander, Silva, Pitman, Michael Mark, Prasad, Rajib, Pyrkosz-Pacyna, Joanna, Rathje, Steve, Raza, Ali, Rego, Gabriel G., Rhee, Kasey, Robertson, Claire E., Rodriguez-Pascual, Ivan, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia C., Santiago-Tovar, Natalia, Savage, David, Scheffer, Julian A., Schonegger, Philipp, Schultner, David T., Schutte, Enid M., Scott, Andy, Sharma, Madhavi, Sharma, Pujan, Skali, Ahmed, Stadelmann, David, Stafford, Clara Alexandra, Stanojevic, Dragan, Stefaniak, Anna, Sternisko, Anni, Stoica, Augustin, Stoyanova, Kristina K., Strickland, Brent, Sundvall, Jukka, Thomas, Jeffrey P., Tinghög, Gustav, Torgler, Benno, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete S., Van Lange, Paul A. M., van Prooijen, Jan-Willem, van Rooy, Dirk, Västfjäll, Daniel, Verkoeijen, Peter, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander Cameron, Watermeyer, Jennifer, Wetter, Erik, Whillans, Ashley, Willardt, Robin, Wohl, Michael J. A., Wojcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin-Theresa, Zwaan, Rolf A., and Boggio, Paulo S.

Abstract

Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic. Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = -0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics., Funding Agencies|John Templeton Foundation (JTF) [61378]; Narodowe Centrum Nauki (National Science Centre) [2018/29/B/HS6/02826, 2015/19/B/HS6/01253]; RCUK | Medical Research Council (MRC)UK Research & Innovation (UKRI)Medical Research Council UK (MRC) [MR/P014097/1]; Economic Social Research Council Impact Acceleration Award; University of Oxford; Gouvernement du Canada | Social Sciences and Humanities Research Council of Canada (Conseil de recherches en sciences humaines du Canada) [130760, SSHRC-506547., 435-2012-1135]; Agentura na Podporu Vyskumu a Vyvoja (Slovak Research and Development Agency) [APVV-17-0596]; Academy of Finland (Suomen Akatemia)Academy of Finland; Austrian Science Fund (Fonds zur Forderung der Wissenschaftlichen Forschung)Austrian Science Fund (FWF) [I3381]; Universitat Wien (University of Vienna); Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan); Aarhus Universitets Forskningsfond (Aarhus University Research Foundation) [AUFF-E-201 9-9-4, 28207]; Vetenskapsradet (Swedish Research Council)Swedish Research Council [2018-00877]; Carlsbergfondet (Carlsberg Foundation)Carlsberg Foundation [CF20-0044]; Ministarstvo Prosvete, Nauke i Tehnolokog Razvoja (Ministry of Education, Science and Technological Development of the Republic of Serbia) [47010]; NOMIS Stiftung (NOMIS Foundation); National Natural Science Foundation of China (National Science Foundation of China)National Natural Science Foundation of China (NSFC) [71972065, 71602163]; RCUK|Biotechnology and Biological Sciences Research Council (BBSRC)UK Research & Innovation (UKRI)Biotechnology and Biological Sciences Research Council (BBSRC) [BB/R010668/1]; Agence Nationale de la Recherche (French National Research Agency)French National Research Agency (ANR) [ANR-17-EURE-0010, ANR-10-IDEX-0001-02 PSL, ANR-17-EURE-0017]; Deutsche Forschungsgemeinschaft (German Research Foundation)German Research Foundation (DFG) [EXC 2052/1 - 390713894]; Gouvern

Published
2022
Full Text
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393. National identity predicts public health support during a global pandemic

Author

Van Bavel, J.J., Cichocka, A., Capraro, V., Sjåstad, H., Nezlek, J.B., Pavlović, T., Alfano, M., Gelfand, M.J., Azevedo, F., Birtel, M.D., Cislak, A., Lockwood, P.L., Ross, R.M., Abts, K., Agadullina, E., Aruta, J.J.B., Besharati, S.N., Bor, A., Choma, B.L., Crabtree, C.D., Cunningham, W.A., De, K., Ejaz, W., Elbaek, C.T., Findor, A., Flichtentrei, D., Franc, R., Gjoneska, B., Gruber, J., Gualda, E., Horiuchi, Y., Huynh, T.L.D., Ibanez, A., Imran, M.A., Israelashvili, J., Jasko, K., Kantorowicz, J., Kantorowicz-Reznichenko, E., Krouwel, A., Laakasuo, M., Lamm, C., Leygue, C., Lin, M.-J., Mansoor, M.S., Marie, A., Mayiwar, L., Mazepus, H., McHugh, C., Minda, J.P., Mitkidis, P., Olsson, A., Otterbring, T., Packer, D.J., Perry, A., Petersen, M.B., Puthillam, A., Riaño-Moreno, J.C., Rothmund, T., Santamaría-García, H., Schmid, P.C., Stoyanov, D., Tewari, S., Todosijević, B., Tsakiris, M., Tung, H.H., Umbreș, R.G., Vanags, E., Vlasceanu, M., Vonasch, A., Yucel, M., Zhang, Y., Abad, M., Adler, E., Akrawi, N., Mdarhri, H.A., Amara, H., Amodio, D.M., Antazo, B.G., Apps, M., Ay, F.C., Ba, M.H., Barbosa, S., Bastian, B., Berg, A., Bernal-Zárate, M.P., Bernstein, M., Białek, M., Bilancini, E., Bogatyreva, N., Boncinelli, L., Booth, J.E., Borau, S., Buchel, O., Cameron, C.D., Carvalho, C.F., Celadin, T., Cerami, C., Chalise, H.N., Cheng, X., Cian, L., Cockcroft, K., Conway, J., Córdoba-Delgado, M.A., Crespi, C., Crouzevialle, M., Cutler, J., Cypryańska, M., Dabrowska, J., Daniels, M.A., Davis, V.H., Dayley, P.N., Delouvee, S., Denkovski, O., Dezecache, G., Dhaliwal, N.A., Diato, A.B., Di Paolo, R., Drosinou, M., Dulleck, U., Ekmanis, J., Ertan, A.S., Etienne, T.W., Farhana, H.H., Farkhari, F., Farmer, H., Fenwick, A., Fidanovski, K., Flew, T., Fraser, S., Frempong, R.B., Fugelsang, J.A., Gale, J., Garcia-Navarro, E.B., Garladinne, P., Ghajjou, O., Gkinopoulos, T., Gray, K., Griffin, S.M., Gronfeldt, B., Gümren, M., Gurung, R.L., Halperin, E., Harris, E., Herzon, V., Hruška, M., Huang, G., Hudecek, M.F.C., Isler, O., Jangard, S., Jørgensen, F.J., Kachanoff, F., Kahn, J., Dangol, A.K., Keudel, O., Koppel, L., Koverola, M., Kubin, E., Kunnari, A., Kutiyski, Y., Laguna, O., Leota, J., Lermer, E., Levy, J., Levy, N., Li, C., Long, E.U., Longoni, C., Maglić, M., McCashin, D., Metcalf, A.L., Mikloušić, I., El Mimouni, S., Miura, A., Molina-Paredes, J., Monroy-Fonseca, C., Morales-Marente, E., Moreau, D., Muda, R., Myer, A., Nash, K., Nesh-Nash, T., Nitschke, J.P., Nurse, M.S., Ohtsubo, Y., Oldemburgo de Mello, V., O’Madagain, C., Onderco, M., Palacios-Galvez, M.S., Palomäki, J., Pan, Y., Papp, Z., Pärnamets, P., Paruzel-Czachura, M., Pavlović, Z., Payán-Gómez, C., Perander, S., Pitman, M.M., Prasad, R., Pyrkosz-Pacyna, J., Rathje, S., Raza, A., Rêgo, G.G., Rhee, K., Robertson, C.E., Rodríguez-Pascual, I., Saikkonen, T., Salvador-Ginez, O., Sampaio, W.M., Santi, G.C., Santiago-Tovar, N., Savage, D., Scheffer, J.A., Schönegger, P., Schultner, D.T., Schutte, E.M., Scott, A., Sharma, M., Sharma, P., Skali, A., Stadelmann, D., Stafford, C.A., Stanojević, D., Stefaniak, A., Sternisko, A., Stoica, A., Stoyanova, K.K., Strickland, B., Sundvall, J., Thomas, J.P., Tinghög, G., Torgler, B., Traast, I.J., Tucciarelli, R., Tyrala, M., Ungson, N.D., Uysal, M.S., Van Lange, P.A.M., van Prooijen, J.-W., van Rooy, D., Västfjäll, D., Verkoeijen, P., Vieira, J.B., von Sikorski, C., Walker, A.C., Watermeyer, J., Wetter, E., Whillans, A., Willardt, R., Wohl, M.J.A., Wójcik, A.D., Wu, K., Yamada, Y., Yilmaz, O., Yogeeswaran, K., Ziemer, C.-T., Zwaan, R.A., Boggio, P.S., Van Bavel, J.J., Cichocka, A., Capraro, V., Sjåstad, H., Nezlek, J.B., Pavlović, T., Alfano, M., Gelfand, M.J., Azevedo, F., Birtel, M.D., Cislak, A., Lockwood, P.L., Ross, R.M., Abts, K., Agadullina, E., Aruta, J.J.B., Besharati, S.N., Bor, A., Choma, B.L., Crabtree, C.D., Cunningham, W.A., De, K., Ejaz, W., Elbaek, C.T., Findor, A., Flichtentrei, D., Franc, R., Gjoneska, B., Gruber, J., Gualda, E., Horiuchi, Y., Huynh, T.L.D., Ibanez, A., Imran, M.A., Israelashvili, J., Jasko, K., Kantorowicz, J., Kantorowicz-Reznichenko, E., Krouwel, A., Laakasuo, M., Lamm, C., Leygue, C., Lin, M.-J., Mansoor, M.S., Marie, A., Mayiwar, L., Mazepus, H., McHugh, C., Minda, J.P., Mitkidis, P., Olsson, A., Otterbring, T., Packer, D.J., Perry, A., Petersen, M.B., Puthillam, A., Riaño-Moreno, J.C., Rothmund, T., Santamaría-García, H., Schmid, P.C., Stoyanov, D., Tewari, S., Todosijević, B., Tsakiris, M., Tung, H.H., Umbreș, R.G., Vanags, E., Vlasceanu, M., Vonasch, A., Yucel, M., Zhang, Y., Abad, M., Adler, E., Akrawi, N., Mdarhri, H.A., Amara, H., Amodio, D.M., Antazo, B.G., Apps, M., Ay, F.C., Ba, M.H., Barbosa, S., Bastian, B., Berg, A., Bernal-Zárate, M.P., Bernstein, M., Białek, M., Bilancini, E., Bogatyreva, N., Boncinelli, L., Booth, J.E., Borau, S., Buchel, O., Cameron, C.D., Carvalho, C.F., Celadin, T., Cerami, C., Chalise, H.N., Cheng, X., Cian, L., Cockcroft, K., Conway, J., Córdoba-Delgado, M.A., Crespi, C., Crouzevialle, M., Cutler, J., Cypryańska, M., Dabrowska, J., Daniels, M.A., Davis, V.H., Dayley, P.N., Delouvee, S., Denkovski, O., Dezecache, G., Dhaliwal, N.A., Diato, A.B., Di Paolo, R., Drosinou, M., Dulleck, U., Ekmanis, J., Ertan, A.S., Etienne, T.W., Farhana, H.H., Farkhari, F., Farmer, H., Fenwick, A., Fidanovski, K., Flew, T., Fraser, S., Frempong, R.B., Fugelsang, J.A., Gale, J., Garcia-Navarro, E.B., Garladinne, P., Ghajjou, O., Gkinopoulos, T., Gray, K., Griffin, S.M., Gronfeldt, B., Gümren, M., Gurung, R.L., Halperin, E., Harris, E., Herzon, V., Hruška, M., Huang, G., Hudecek, M.F.C., Isler, O., Jangard, S., Jørgensen, F.J., Kachanoff, F., Kahn, J., Dangol, A.K., Keudel, O., Koppel, L., Koverola, M., Kubin, E., Kunnari, A., Kutiyski, Y., Laguna, O., Leota, J., Lermer, E., Levy, J., Levy, N., Li, C., Long, E.U., Longoni, C., Maglić, M., McCashin, D., Metcalf, A.L., Mikloušić, I., El Mimouni, S., Miura, A., Molina-Paredes, J., Monroy-Fonseca, C., Morales-Marente, E., Moreau, D., Muda, R., Myer, A., Nash, K., Nesh-Nash, T., Nitschke, J.P., Nurse, M.S., Ohtsubo, Y., Oldemburgo de Mello, V., O’Madagain, C., Onderco, M., Palacios-Galvez, M.S., Palomäki, J., Pan, Y., Papp, Z., Pärnamets, P., Paruzel-Czachura, M., Pavlović, Z., Payán-Gómez, C., Perander, S., Pitman, M.M., Prasad, R., Pyrkosz-Pacyna, J., Rathje, S., Raza, A., Rêgo, G.G., Rhee, K., Robertson, C.E., Rodríguez-Pascual, I., Saikkonen, T., Salvador-Ginez, O., Sampaio, W.M., Santi, G.C., Santiago-Tovar, N., Savage, D., Scheffer, J.A., Schönegger, P., Schultner, D.T., Schutte, E.M., Scott, A., Sharma, M., Sharma, P., Skali, A., Stadelmann, D., Stafford, C.A., Stanojević, D., Stefaniak, A., Sternisko, A., Stoica, A., Stoyanova, K.K., Strickland, B., Sundvall, J., Thomas, J.P., Tinghög, G., Torgler, B., Traast, I.J., Tucciarelli, R., Tyrala, M., Ungson, N.D., Uysal, M.S., Van Lange, P.A.M., van Prooijen, J.-W., van Rooy, D., Västfjäll, D., Verkoeijen, P., Vieira, J.B., von Sikorski, C., Walker, A.C., Watermeyer, J., Wetter, E., Whillans, A., Willardt, R., Wohl, M.J.A., Wójcik, A.D., Wu, K., Yamada, Y., Yilmaz, O., Yogeeswaran, K., Ziemer, C.-T., Zwaan, R.A., and Boggio, P.S.

Abstract

Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = −0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.

Published
2022

394. National identity predicts public health support during a global pandemic

Author

Van Bavel, JJ, Cichocka, A, Capraro, V, Sjastad, H, Nezlek, JB, Pavlovic, T, Alfano, M, Gelfand, MJ, Azevedo, F, Birtel, MD, Cislak, A, Lockwood, PL, Ross, RM, Abts, K, Agadullina, E, Aruta, JJB, Besharati, SN, Bor, A, Choma, BL, Crabtree, CD, Cunningham, WA, De, K, Ejaz, W, Elbaek, CT, Findor, A, Flichtentrei, D, Franc, R, Gjoneska, B, Gruber, J, Gualda, E, Horiuchi, Y, Toan, LDH, Ibanez, A, Imran, MA, Israelashvili, J, Jasko, K, Kantorowicz, J, Kantorowicz-Reznichenko, E, Krouwel, A, Laakasuo, M, Lamm, C, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Minda, JP, Mitkidis, P, Olsson, A, Otterbring, T, Packer, DJ, Perry, A, Petersen, MB, Puthillam, A, Riano-Moreno, JC, Rothmund, T, Santamaria-Garcia, H, Schmid, PC, Stoyanov, D, Tewari, S, Todosijevic, B, Tsakiris, M, Tung, HH, Umbres, RG, Vanags, E, Vlasceanu, M, Vonasch, A, Yucel, M, Zhang, Y, Abad, M, Adler, E, Akrawi, N, Mdarhri, HA, Amara, H, Amodio, DM, Antazo, BG, Apps, M, Ay, FC, Ba, MH, Barbosa, S, Bastian, B, Berg, A, Bernal-Zarate, MP, Bernstein, M, Bialek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, Cameron, CD, Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Andres Cordoba-Delgado, M, Crespi, C, Crouzevialle, M, Cutler, J, Dabrowska, J, Cypryanska, M, Daniels, MA, Davis, VH, Dayley, PN, Delouvee, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, AB, Di Paolo, R, Drosinou, M, Dulleck, U, Ekmanis, J, Ertan, AS, Etienne, TW, Farhana, HH, Farkhari, F, Farmer, H, Fenwick, A, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, JA, Gale, J, Begona Garcia-Navarro, E, Garladinne, P, Ghajjou, O, Gkinopoulos, T, Gray, K, Griffin, SM, Gronfeldt, B, Gumren, M, Gurung, RL, Halperin, E, Harris, E, Herzon, V, Hruska, M, Huang, G, Hudecek, MFC, Isler, O, Jangard, S, Jorgensen, FJ, Kachanoff, F, Kahn, J, Dangol, AK, Keudel, O, Koppel, L, Koverola, M, Kubin, E, Kunnari, A, Kutiyski, Y, Laguna, O, Leota, J, Lermer, E, Levy, J, Levy, N, Li, C, Long, EU, Longoni, C, Maglic, M, McCashin, D, Metcalf, AL, Miklousic, I, El Mimouni, S, Miura, A, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nesh-Nash, T, Nitschke, JP, Nurse, MS, Ohtsubo, Y, de Mello, VO, O'Madagain, C, Onderco, M, Soledad Palacios-Galvez, M, Palomaki, J, Pan, Y, Papp, Z, Parnamets, P, Paruzel-Czachura, M, Pavlovic, Z, Payan-Gomez, C, Perander, S, Pitman, MM, Prasad, R, Pyrkosz-Pacyna, J, Rathje, S, Raza, A, Rego, GG, Rhee, K, Robertson, CE, Rodriguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Santiago-Tovar, N, Savage, D, Scheffer, JA, Schonegger, P, Schultner, DT, Schutte, EM, Scott, A, Sharma, M, Sharma, P, Skali, A, Stadelmann, D, Stafford, CA, Stanojevic, D, Stefaniak, A, Sternisko, A, Stoica, A, Stoyanova, KK, Strickland, B, Sundvall, J, Thomas, JP, Tinghog, G, Torgler, B, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Lange, PAM, van Prooijen, J-W, van Rooy, D, Vastfjall, D, Verkoeijen, P, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Wetter, E, Whillans, A, Willardt, R, Wohl, MJA, Wojcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, Boggio, PS, Van Bavel, JJ, Cichocka, A, Capraro, V, Sjastad, H, Nezlek, JB, Pavlovic, T, Alfano, M, Gelfand, MJ, Azevedo, F, Birtel, MD, Cislak, A, Lockwood, PL, Ross, RM, Abts, K, Agadullina, E, Aruta, JJB, Besharati, SN, Bor, A, Choma, BL, Crabtree, CD, Cunningham, WA, De, K, Ejaz, W, Elbaek, CT, Findor, A, Flichtentrei, D, Franc, R, Gjoneska, B, Gruber, J, Gualda, E, Horiuchi, Y, Toan, LDH, Ibanez, A, Imran, MA, Israelashvili, J, Jasko, K, Kantorowicz, J, Kantorowicz-Reznichenko, E, Krouwel, A, Laakasuo, M, Lamm, C, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Minda, JP, Mitkidis, P, Olsson, A, Otterbring, T, Packer, DJ, Perry, A, Petersen, MB, Puthillam, A, Riano-Moreno, JC, Rothmund, T, Santamaria-Garcia, H, Schmid, PC, Stoyanov, D, Tewari, S, Todosijevic, B, Tsakiris, M, Tung, HH, Umbres, RG, Vanags, E, Vlasceanu, M, Vonasch, A, Yucel, M, Zhang, Y, Abad, M, Adler, E, Akrawi, N, Mdarhri, HA, Amara, H, Amodio, DM, Antazo, BG, Apps, M, Ay, FC, Ba, MH, Barbosa, S, Bastian, B, Berg, A, Bernal-Zarate, MP, Bernstein, M, Bialek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, Cameron, CD, Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Andres Cordoba-Delgado, M, Crespi, C, Crouzevialle, M, Cutler, J, Dabrowska, J, Cypryanska, M, Daniels, MA, Davis, VH, Dayley, PN, Delouvee, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, AB, Di Paolo, R, Drosinou, M, Dulleck, U, Ekmanis, J, Ertan, AS, Etienne, TW, Farhana, HH, Farkhari, F, Farmer, H, Fenwick, A, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, JA, Gale, J, Begona Garcia-Navarro, E, Garladinne, P, Ghajjou, O, Gkinopoulos, T, Gray, K, Griffin, SM, Gronfeldt, B, Gumren, M, Gurung, RL, Halperin, E, Harris, E, Herzon, V, Hruska, M, Huang, G, Hudecek, MFC, Isler, O, Jangard, S, Jorgensen, FJ, Kachanoff, F, Kahn, J, Dangol, AK, Keudel, O, Koppel, L, Koverola, M, Kubin, E, Kunnari, A, Kutiyski, Y, Laguna, O, Leota, J, Lermer, E, Levy, J, Levy, N, Li, C, Long, EU, Longoni, C, Maglic, M, McCashin, D, Metcalf, AL, Miklousic, I, El Mimouni, S, Miura, A, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nesh-Nash, T, Nitschke, JP, Nurse, MS, Ohtsubo, Y, de Mello, VO, O'Madagain, C, Onderco, M, Soledad Palacios-Galvez, M, Palomaki, J, Pan, Y, Papp, Z, Parnamets, P, Paruzel-Czachura, M, Pavlovic, Z, Payan-Gomez, C, Perander, S, Pitman, MM, Prasad, R, Pyrkosz-Pacyna, J, Rathje, S, Raza, A, Rego, GG, Rhee, K, Robertson, CE, Rodriguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Santiago-Tovar, N, Savage, D, Scheffer, JA, Schonegger, P, Schultner, DT, Schutte, EM, Scott, A, Sharma, M, Sharma, P, Skali, A, Stadelmann, D, Stafford, CA, Stanojevic, D, Stefaniak, A, Sternisko, A, Stoica, A, Stoyanova, KK, Strickland, B, Sundvall, J, Thomas, JP, Tinghog, G, Torgler, B, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Lange, PAM, van Prooijen, J-W, van Rooy, D, Vastfjall, D, Verkoeijen, P, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Wetter, E, Whillans, A, Willardt, R, Wohl, MJA, Wojcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, and Boggio, PS

Abstract

Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = -0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.

Published
2022

395. National identity predicts public health support during a global pandemic (vol 13, 517, 2022)

Author

Van Bavel, JJ, Cichocka, A, Capraro, V, Sjastad, H, Nezlek, JB, Pavlovic, T, Alfano, M, Gelfand, MJ, Azevedo, F, Birtel, MD, Cislak, A, Lockwood, PL, Ross, RM, Abts, K, Agadullina, E, Aruta, JJB, Besharati, SN, Bor, A, Choma, BL, Crabtree, CD, Cunningham, WA, De, K, Ejaz, W, Elbaek, CT, Findor, A, Flichtentrei, D, Franc, R, Gjoneska, B, Gruber, J, Gualda, E, Horiuchi, Y, Huynh, TLD, Ibanez, A, Imran, MA, Israelashvili, J, Jasko, K, Kantorowicz, J, Kantorowicz-Reznichenko, E, Krouwel, A, Laakasuo, M, Lamm, C, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Minda, JP, Mitkidis, P, Olsson, A, Otterbring, T, Packer, DJ, Perry, A, Petersen, MB, Puthillam, A, Riano-Moreno, JC, Rothmund, T, Santamaria-Garcia, H, Schmid, PC, Stoyanov, D, Tewari, S, Todosijevic, B, Tsakiris, M, Tung, HH, Umbres, RG, Vanags, E, Vlasceanu, M, Vonasch, A, Yucel, M, Zhang, Y, Abad, M, Adler, E, Akrawi, N, Mdarhri, HA, Amara, H, Amodio, DM, Antazo, BG, Apps, M, Ay, FC, Ba, MH, Barbosa, S, Bastian, B, Berg, A, Bernal-Zarate, MP, Bernstein, M, Bialek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, Cameron, CD, Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Cordoba-Delgado, MA, Crespi, C, Crouzevialle, M, Cutler, J, Cypryanska, M, Dabrowska, J, Daniels, MA, Davis, VH, Dayley, PN, Delouvee, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, AB, Di Paolo, R, Drosinou, M, Dulleck, U, Ekmanis, J, Ertan, AS, Etienne, TW, Farhana, HH, Farkhari, F, Farmer, H, Fenwick, A, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, JA, Gale, J, Garcia-Navarro, EB, Garladinne, P, Ghajjou, O, Gkinopoulos, T, Gray, K, Griffin, SM, Gronfeldt, B, Gumren, M, Gurung, RL, Halperin, E, Harris, E, Herzon, V, Hruska, M, Huang, G, Hudecek, MFC, Isler, O, Jangard, S, Jorgensen, FJ, Kachanoff, F, Kahn, J, Dangol, AK, Keudel, O, Koppel, L, Koverola, M, Kubin, E, Kunnari, A, Kutiyski, Y, Laguna, O, Leota, J, Lermer, E, Levy, J, Levy, N, Li, C, Long, EU, Longoni, C, Maglic, M, McCashin, D, Metcalf, AL, Miklousic, I, El Mimouni, S, Miura, A, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nesh-Nash, T, Nitschke, JP, Nurse, MS, Ohtsubo, Y, Oldemburgo de Mello, V, O'Madagain, C, Onderco, M, Palacios-Galvez, MS, Palomaki, J, Pan, Y, Papp, Z, Parnamets, P, Paruzel-Czachura, M, Pavlovic, Z, Payan-Gomez, C, Perander, S, Pitman, MM, Prasad, R, Pyrkosz-Pacyna, J, Rathje, S, Raza, A, Rego, GG, Rhee, K, Robertson, CE, Rodriguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Santiago-Tovar, N, Savage, D, Scheffer, JA, Schonegger, P, Schultner, DT, Schutte, EM, Scott, A, Sharma, M, Sharma, P, Skali, A, Stadelmann, D, Stafford, CA, Stanojevic, D, Stefaniak, A, Sternisko, A, Stoica, A, Stoyanova, KK, Strickland, B, Sundvall, J, Thomas, JP, Tinghog, G, Torgler, B, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Lange, PAM, van Prooijen, J-W, van Rooy, D, Vastfjall, D, Verkoeijen, P, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Wetter, E, Whillans, A, Willardt, R, Wohl, MJA, Wojcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, Boggio, PS, Van Bavel, JJ, Cichocka, A, Capraro, V, Sjastad, H, Nezlek, JB, Pavlovic, T, Alfano, M, Gelfand, MJ, Azevedo, F, Birtel, MD, Cislak, A, Lockwood, PL, Ross, RM, Abts, K, Agadullina, E, Aruta, JJB, Besharati, SN, Bor, A, Choma, BL, Crabtree, CD, Cunningham, WA, De, K, Ejaz, W, Elbaek, CT, Findor, A, Flichtentrei, D, Franc, R, Gjoneska, B, Gruber, J, Gualda, E, Horiuchi, Y, Huynh, TLD, Ibanez, A, Imran, MA, Israelashvili, J, Jasko, K, Kantorowicz, J, Kantorowicz-Reznichenko, E, Krouwel, A, Laakasuo, M, Lamm, C, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Minda, JP, Mitkidis, P, Olsson, A, Otterbring, T, Packer, DJ, Perry, A, Petersen, MB, Puthillam, A, Riano-Moreno, JC, Rothmund, T, Santamaria-Garcia, H, Schmid, PC, Stoyanov, D, Tewari, S, Todosijevic, B, Tsakiris, M, Tung, HH, Umbres, RG, Vanags, E, Vlasceanu, M, Vonasch, A, Yucel, M, Zhang, Y, Abad, M, Adler, E, Akrawi, N, Mdarhri, HA, Amara, H, Amodio, DM, Antazo, BG, Apps, M, Ay, FC, Ba, MH, Barbosa, S, Bastian, B, Berg, A, Bernal-Zarate, MP, Bernstein, M, Bialek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, Cameron, CD, Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Cordoba-Delgado, MA, Crespi, C, Crouzevialle, M, Cutler, J, Cypryanska, M, Dabrowska, J, Daniels, MA, Davis, VH, Dayley, PN, Delouvee, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, AB, Di Paolo, R, Drosinou, M, Dulleck, U, Ekmanis, J, Ertan, AS, Etienne, TW, Farhana, HH, Farkhari, F, Farmer, H, Fenwick, A, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, JA, Gale, J, Garcia-Navarro, EB, Garladinne, P, Ghajjou, O, Gkinopoulos, T, Gray, K, Griffin, SM, Gronfeldt, B, Gumren, M, Gurung, RL, Halperin, E, Harris, E, Herzon, V, Hruska, M, Huang, G, Hudecek, MFC, Isler, O, Jangard, S, Jorgensen, FJ, Kachanoff, F, Kahn, J, Dangol, AK, Keudel, O, Koppel, L, Koverola, M, Kubin, E, Kunnari, A, Kutiyski, Y, Laguna, O, Leota, J, Lermer, E, Levy, J, Levy, N, Li, C, Long, EU, Longoni, C, Maglic, M, McCashin, D, Metcalf, AL, Miklousic, I, El Mimouni, S, Miura, A, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nesh-Nash, T, Nitschke, JP, Nurse, MS, Ohtsubo, Y, Oldemburgo de Mello, V, O'Madagain, C, Onderco, M, Palacios-Galvez, MS, Palomaki, J, Pan, Y, Papp, Z, Parnamets, P, Paruzel-Czachura, M, Pavlovic, Z, Payan-Gomez, C, Perander, S, Pitman, MM, Prasad, R, Pyrkosz-Pacyna, J, Rathje, S, Raza, A, Rego, GG, Rhee, K, Robertson, CE, Rodriguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Santiago-Tovar, N, Savage, D, Scheffer, JA, Schonegger, P, Schultner, DT, Schutte, EM, Scott, A, Sharma, M, Sharma, P, Skali, A, Stadelmann, D, Stafford, CA, Stanojevic, D, Stefaniak, A, Sternisko, A, Stoica, A, Stoyanova, KK, Strickland, B, Sundvall, J, Thomas, JP, Tinghog, G, Torgler, B, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Lange, PAM, van Prooijen, J-W, van Rooy, D, Vastfjall, D, Verkoeijen, P, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Wetter, E, Whillans, A, Willardt, R, Wohl, MJA, Wojcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, and Boggio, PS

Published
2022

396. Monastic treasures between memory and dispersion

Author

Cerami, Domenico and Cerami, Domenico

Abstract

This study focuses on the meaning and acquisition of the word thesaurus in monastic early medieval sources. The term essentially refers to objects characterized by strong symbolic, economic, cultural and sumptuary value. In the monastic Rules the word does not appear because the forms of accumulation and conservation of wealth were extraneous to the vow of poverty disciplined and emphasized by the drafters. With the growth of the monasteries, the promise of royal protection, the strengthening of ties with the power elites and the establishment of the institution of exemption, the treasures grow in importance, underlining the prestige acquired by the single monastery. The objects that compose it become a non-secondary element of what we can define the material memory of the monastic community, providing information on patrons, on the workshops active in the monastery, on the exchanges established with monastic foundations and with local communities, on donations from power groups active in the territory and finally on the subtraction and dispersion suffered.

Published
2022

397. Using Corneal Confocal Microscopy to Identify Therapeutic Agents for Diabetic Neuropathy.

Author

Jolivalt, Corinne G, Jolivalt, Corinne G, Han, May Madi, Nguyen, Annee, Desmond, Fiona, Alves Jesus, Carlos Henrique, Vasconselos, Daniela C, Pedneault, Andrea, Sandlin, Natalie, Dunne-Cerami, Sage, Frizzi, Katie E, Calcutt, Nigel A, Jolivalt, Corinne G, Jolivalt, Corinne G, Han, May Madi, Nguyen, Annee, Desmond, Fiona, Alves Jesus, Carlos Henrique, Vasconselos, Daniela C, Pedneault, Andrea, Sandlin, Natalie, Dunne-Cerami, Sage, Frizzi, Katie E, and Calcutt, Nigel A

Abstract

Corneal confocal microscopy (CCM) is emerging as a tool for identifying small fiber neuropathy in both peripheral neuropathies and neurodegenerative disease of the central nervous system (CNS). The value of corneal nerves as biomarkers for efficacy of clinical interventions against small fiber neuropathy and neurodegenerative disease is less clear but may be supported by preclinical studies of investigational agents. We, therefore, used diverse investigational agents to assess concordance of efficacy against corneal nerve loss and peripheral neuropathy in a mouse model of diabetes. Ocular delivery of the peptides ciliary neurotrophic factor (CNTF) or the glucagon-like peptide (GLP) analog exendin-4, both of which prevent diabetic neuropathy when given systemically, restored corneal nerve density within 2 weeks. Similarly, ocular delivery of the muscarinic receptor antagonist cyclopentolate protected corneal nerve density while concurrently reversing indices of systemic peripheral neuropathy. Conversely, systemic delivery of the muscarinic antagonist glycopyrrolate, but not gallamine, prevented multiple indices of systemic peripheral neuropathy and concurrently protected against corneal nerve loss. These data highlight the potential for use of corneal nerve quantification by confocal microscopy as a bridging assay between in vitro and whole animal assays in drug development programs for neuroprotectants and support its use as a biomarker of efficacy against peripheral neuropathy.

Published
2022

398. Predicting attitudinal and behavioral responses to COVID-19 pandemic using machine learning.

Author

Pavlović, T, Azevedo, F, De, K, Riaño-Moreno, JC, Maglić, M, Gkinopoulos, T, Donnelly-Kehoe, PA, Payán-Gómez, C, Huang, G, Kantorowicz, J, Birtel, MD, Schönegger, P, Capraro, V, Santamaría-García, H, Yucel, M, Ibanez, A, Rathje, S, Wetter, E, Stanojević, D, van Prooijen, J-W, Hesse, E, Elbaek, CT, Franc, R, Pavlović, Z, Mitkidis, P, Cichocka, A, Gelfand, M, Alfano, M, Ross, RM, Sjåstad, H, Nezlek, JB, Cislak, A, Lockwood, P, Abts, K, Agadullina, E, Amodio, DM, Apps, MAJ, Aruta, JJB, Besharati, S, Bor, A, Choma, B, Cunningham, W, Ejaz, W, Farmer, H, Findor, A, Gjoneska, B, Gualda, E, Huynh, TLD, Imran, MA, Israelashvili, J, Kantorowicz-Reznichenko, E, Krouwel, A, Kutiyski, Y, Laakasuo, M, Lamm, C, Levy, J, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Olsson, A, Otterbring, T, Packer, D, Palomäki, J, Perry, A, Petersen, MB, Puthillam, A, Rothmund, T, Schmid, PC, Stadelmann, D, Stoica, A, Stoyanov, D, Stoyanova, K, Tewari, S, Todosijević, B, Torgler, B, Tsakiris, M, Tung, HH, Umbreș, RG, Vanags, E, Vlasceanu, M, Vonasch, AJ, Zhang, Y, Abad, M, Adler, E, Mdarhri, HA, Antazo, B, Ay, FC, Ba, MEH, Barbosa, S, Bastian, B, Berg, A, Białek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, de Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Córdoba-Delgado, MA, Crespi, C, Crouzevialle, M, Cutler, J, Cypryańska, M, Dabrowska, J, Davis, VH, Minda, JP, Dayley, PN, Delouvée, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, A, Di Paolo, R, Dulleck, U, Ekmanis, J, Etienne, TW, Farhana, HH, Farkhari, F, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, J, Gale, J, García-Navarro, EB, Garladinne, P, Gray, K, Griffin, SM, Gronfeldt, B, Gruber, J, Halperin, E, Herzon, V, Hruška, M, Hudecek, MFC, Isler, O, Jangard, S, Jørgensen, F, Keudel, O, Koppel, L, Koverola, M, Kunnari, A, Leota, J, Lermer, E, Li, C, Longoni, C, McCashin, D, Mikloušić, I, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nitschke, JP, Nurse, MS, de Mello, VO, Palacios-Galvez, MS, Pan, Y, Papp, Z, Pärnamets, P, Paruzel-Czachura, M, Perander, S, Pitman, M, Raza, A, Rêgo, GG, Robertson, C, Rodríguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Schultner, D, Schutte, E, Scott, A, Skali, A, Stefaniak, A, Sternisko, A, Strickland, B, Thomas, JP, Tinghög, G, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Rooy, D, Västfjäll, D, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Willardt, R, Wohl, MJA, Wójcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, Boggio, PS, Whillans, A, Van Lange, PAM, Prasad, R, Onderco, M, O'Madagain, C, Nesh-Nash, T, Laguna, OM, Kubin, E, Gümren, M, Fenwick, A, Ertan, AS, Bernstein, MJ, Amara, H, Van Bavel, JJ, Pavlović, T, Azevedo, F, De, K, Riaño-Moreno, JC, Maglić, M, Gkinopoulos, T, Donnelly-Kehoe, PA, Payán-Gómez, C, Huang, G, Kantorowicz, J, Birtel, MD, Schönegger, P, Capraro, V, Santamaría-García, H, Yucel, M, Ibanez, A, Rathje, S, Wetter, E, Stanojević, D, van Prooijen, J-W, Hesse, E, Elbaek, CT, Franc, R, Pavlović, Z, Mitkidis, P, Cichocka, A, Gelfand, M, Alfano, M, Ross, RM, Sjåstad, H, Nezlek, JB, Cislak, A, Lockwood, P, Abts, K, Agadullina, E, Amodio, DM, Apps, MAJ, Aruta, JJB, Besharati, S, Bor, A, Choma, B, Cunningham, W, Ejaz, W, Farmer, H, Findor, A, Gjoneska, B, Gualda, E, Huynh, TLD, Imran, MA, Israelashvili, J, Kantorowicz-Reznichenko, E, Krouwel, A, Kutiyski, Y, Laakasuo, M, Lamm, C, Levy, J, Leygue, C, Lin, M-J, Mansoor, MS, Marie, A, Mayiwar, L, Mazepus, H, McHugh, C, Olsson, A, Otterbring, T, Packer, D, Palomäki, J, Perry, A, Petersen, MB, Puthillam, A, Rothmund, T, Schmid, PC, Stadelmann, D, Stoica, A, Stoyanov, D, Stoyanova, K, Tewari, S, Todosijević, B, Torgler, B, Tsakiris, M, Tung, HH, Umbreș, RG, Vanags, E, Vlasceanu, M, Vonasch, AJ, Zhang, Y, Abad, M, Adler, E, Mdarhri, HA, Antazo, B, Ay, FC, Ba, MEH, Barbosa, S, Bastian, B, Berg, A, Białek, M, Bilancini, E, Bogatyreva, N, Boncinelli, L, Booth, JE, Borau, S, Buchel, O, de Carvalho, CF, Celadin, T, Cerami, C, Chalise, HN, Cheng, X, Cian, L, Cockcroft, K, Conway, J, Córdoba-Delgado, MA, Crespi, C, Crouzevialle, M, Cutler, J, Cypryańska, M, Dabrowska, J, Davis, VH, Minda, JP, Dayley, PN, Delouvée, S, Denkovski, O, Dezecache, G, Dhaliwal, NA, Diato, A, Di Paolo, R, Dulleck, U, Ekmanis, J, Etienne, TW, Farhana, HH, Farkhari, F, Fidanovski, K, Flew, T, Fraser, S, Frempong, RB, Fugelsang, J, Gale, J, García-Navarro, EB, Garladinne, P, Gray, K, Griffin, SM, Gronfeldt, B, Gruber, J, Halperin, E, Herzon, V, Hruška, M, Hudecek, MFC, Isler, O, Jangard, S, Jørgensen, F, Keudel, O, Koppel, L, Koverola, M, Kunnari, A, Leota, J, Lermer, E, Li, C, Longoni, C, McCashin, D, Mikloušić, I, Molina-Paredes, J, Monroy-Fonseca, C, Morales-Marente, E, Moreau, D, Muda, R, Myer, A, Nash, K, Nitschke, JP, Nurse, MS, de Mello, VO, Palacios-Galvez, MS, Pan, Y, Papp, Z, Pärnamets, P, Paruzel-Czachura, M, Perander, S, Pitman, M, Raza, A, Rêgo, GG, Robertson, C, Rodríguez-Pascual, I, Saikkonen, T, Salvador-Ginez, O, Sampaio, WM, Santi, GC, Schultner, D, Schutte, E, Scott, A, Skali, A, Stefaniak, A, Sternisko, A, Strickland, B, Thomas, JP, Tinghög, G, Traast, IJ, Tucciarelli, R, Tyrala, M, Ungson, ND, Uysal, MS, Van Rooy, D, Västfjäll, D, Vieira, JB, von Sikorski, C, Walker, AC, Watermeyer, J, Willardt, R, Wohl, MJA, Wójcik, AD, Wu, K, Yamada, Y, Yilmaz, O, Yogeeswaran, K, Ziemer, C-T, Zwaan, RA, Boggio, PS, Whillans, A, Van Lange, PAM, Prasad, R, Onderco, M, O'Madagain, C, Nesh-Nash, T, Laguna, OM, Kubin, E, Gümren, M, Fenwick, A, Ertan, AS, Bernstein, MJ, Amara, H, and Van Bavel, JJ

Abstract

At the beginning of 2020, COVID-19 became a global problem. Despite all the efforts to emphasize the relevance of preventive measures, not everyone adhered to them. Thus, learning more about the characteristics determining attitudinal and behavioral responses to the pandemic is crucial to improving future interventions. In this study, we applied machine learning on the multinational data collected by the International Collaboration on the Social and Moral Psychology of COVID-19 (N = 51,404) to test the predictive efficacy of constructs from social, moral, cognitive, and personality psychology, as well as socio-demographic factors, in the attitudinal and behavioral responses to the pandemic. The results point to several valuable insights. Internalized moral identity provided the most consistent predictive contribution-individuals perceiving moral traits as central to their self-concept reported higher adherence to preventive measures. Similar results were found for morality as cooperation, symbolized moral identity, self-control, open-mindedness, and collective narcissism, while the inverse relationship was evident for the endorsement of conspiracy theories. However, we also found a non-neglible variability in the explained variance and predictive contributions with respect to macro-level factors such as the pandemic stage or cultural region. Overall, the results underscore the importance of morality-related and contextual factors in understanding adherence to public health recommendations during the pandemic.

Published
2022

399. Predicting attitudinal and behavioral responses to COVID-19 pandemic using machine learning

Author

Pavlović, Tomislav, Azevedo, Flavio, De, Koustav, Riaño-Moreno, Julián C., Maglić, Marina, Gkinopoulos, Theofilos, Donnelly-Kehoe, Patricio Andreas, Payán-Gómez, César, Huang, Guanxiong, Kantorowicz, Jaroslaw, Birtel, Michèle D., Schönegger, Philipp, Capraro, Valerio, Santamaría-García, Hernando, Yucel, Meltem, Ibanez, Agustin, Rathje, Steve, Wetter, Erik, Stanojević, Dragan, van Prooijen, Jan-Willem, Hesse, Eugenia, Elbaek, Christian T., Franc, Renata, Pavlović, Zoran, Mitkidis, Panagiotis, Cichocka, Aleksandra, Gelfand, Michele J., Alfano, Mark, Ross, Robert M., Sjåstad, Hallgeir, Nezlek, John B., Cislak, Aleksandra, Lockwood, Patricia L., Abts, Koen, Agadullina, Elena, Amodio, David M., Apps, Matthew A J, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Cunningham, William A., Ejaz, Waqas, Farmer, Harry, Findor, Andrej, Gjoneska, Biljana, Gualda, Estrella, Huynh, Toan L D, Imran, Mostak Ahamed, Israelashvili, Jacob, Kantorowicz-Reznichenko, Elena, Krouwel, André, Kutiyski, Yordan, Laakasuo, Michael, Lamm, Claus, Levy, Jonathan, Leygue, Caroline, Lin, Ming-Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Palomäki, Jussi, Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Rothmund, Tobias, Schmid, Petra C., Stadelmann, David, Stoica, Augustin, Stoyanov, Drozdstoy, Stoyanova, Kristina K., Tewari, Shruti, Todosijević, Bojan, Torgler, Benno, Tsakiris, Manos, Tung, Hans H., Umbreș, Radu Gabriel, Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew J, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Mdarhri, Hamza Alaoui, Antazo, Benedict G., Ay, F. Ceren, Ba, Mouhamadou El Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Białek, Michał, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, de Carvalho, Chrissie Ferreira, Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Córdoba-Delgado, Mateo A, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Cypryańska, Marzena, Dabrowska, Justyna, Davis, Victoria H., Minda, John Paul, Dayley, Pamala N., Delouvée, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Dulleck, Uwe, Ekmanis, Jānis, Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, García-Navarro, E Begoña, Garladinne, Prasad, Gray, Kurt, Griffin, Siobhán M., Gronfeldt, Bjarki, Gruber, June, Halperin, Eran, Herzon, Volo, Hruška, Matej, Hudecek, Matthias F. C., Isler, Ozan, Jangard, Simon, Jørgensen, Frederik J., Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kunnari, Anton, Leota, Josh, Lermer, Eva, Li, Chunyun, Longoni, Chiara, McCashin, Darragh, Mikloušić, Igor, Molina-Paredes, Juliana, Monroy-Fonseca, César, Morales-Marente, Elena, Moreau, David, Muda, Rafał, Myer, Annalisa, Nash, Kyle, Nitschke, Jonas P., Nurse, Matthew S., de Mello, Victoria Oldemburgo, Palacios-Galvez, Maria Soledad, Pan, Yafeng, Papp, Zsófia, Pärnamets, Philip, Paruzel-Czachura, Mariola, Perander, Silva, Pitman, Michael Mark, Raza, Ali, Rêgo, Gabriel Gaudencio, Robertson, Claire E., Rodríguez-Pascual, Iván, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia Chiara, Schultner, David T., Schutte, Enid M., Scott, Andy, Skali, Ahmed, Stefaniak, Anna, Sternisko, Anni, Strickland, Brent, Thomas, Jeffrey P., Tinghög, Gustav, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete Sefa, van Rooy, Dirk, Västfjäll, Daniel, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander C, Watermeyer, Jennifer, Willardt, Robin, Wohl, Michael J. A., Wójcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin-Theresa, Zwaan, Rolf A., Boggio, Paulo S., Whillans, Ashley, Van Lange, Paul A. M., Prasad, Rajib, Onderco, Michal, O’Madagain, Cathal, Nesh-Nash, Tarik, Laguna, Oscar Moreda, Kubin, Emily, Gümren, Mert, Fenwick, Ali, Ertan, Arhan S., Bernstein, Michael J, Amara, Hanane, Van Bavel, Jay J., Pavlović, Tomislav, Azevedo, Flavio, De, Koustav, Riaño-Moreno, Julián C., Maglić, Marina, Gkinopoulos, Theofilos, Donnelly-Kehoe, Patricio Andreas, Payán-Gómez, César, Huang, Guanxiong, Kantorowicz, Jaroslaw, Birtel, Michèle D., Schönegger, Philipp, Capraro, Valerio, Santamaría-García, Hernando, Yucel, Meltem, Ibanez, Agustin, Rathje, Steve, Wetter, Erik, Stanojević, Dragan, van Prooijen, Jan-Willem, Hesse, Eugenia, Elbaek, Christian T., Franc, Renata, Pavlović, Zoran, Mitkidis, Panagiotis, Cichocka, Aleksandra, Gelfand, Michele J., Alfano, Mark, Ross, Robert M., Sjåstad, Hallgeir, Nezlek, John B., Cislak, Aleksandra, Lockwood, Patricia L., Abts, Koen, Agadullina, Elena, Amodio, David M., Apps, Matthew A J, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Cunningham, William A., Ejaz, Waqas, Farmer, Harry, Findor, Andrej, Gjoneska, Biljana, Gualda, Estrella, Huynh, Toan L D, Imran, Mostak Ahamed, Israelashvili, Jacob, Kantorowicz-Reznichenko, Elena, Krouwel, André, Kutiyski, Yordan, Laakasuo, Michael, Lamm, Claus, Levy, Jonathan, Leygue, Caroline, Lin, Ming-Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Palomäki, Jussi, Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Rothmund, Tobias, Schmid, Petra C., Stadelmann, David, Stoica, Augustin, Stoyanov, Drozdstoy, Stoyanova, Kristina K., Tewari, Shruti, Todosijević, Bojan, Torgler, Benno, Tsakiris, Manos, Tung, Hans H., Umbreș, Radu Gabriel, Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew J, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Mdarhri, Hamza Alaoui, Antazo, Benedict G., Ay, F. Ceren, Ba, Mouhamadou El Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Białek, Michał, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, de Carvalho, Chrissie Ferreira, Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Córdoba-Delgado, Mateo A, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Cypryańska, Marzena, Dabrowska, Justyna, Davis, Victoria H., Minda, John Paul, Dayley, Pamala N., Delouvée, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Dulleck, Uwe, Ekmanis, Jānis, Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, García-Navarro, E Begoña, Garladinne, Prasad, Gray, Kurt, Griffin, Siobhán M., Gronfeldt, Bjarki, Gruber, June, Halperin, Eran, Herzon, Volo, Hruška, Matej, Hudecek, Matthias F. C., Isler, Ozan, Jangard, Simon, Jørgensen, Frederik J., Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kunnari, Anton, Leota, Josh, Lermer, Eva, Li, Chunyun, Longoni, Chiara, McCashin, Darragh, Mikloušić, Igor, Molina-Paredes, Juliana, Monroy-Fonseca, César, Morales-Marente, Elena, Moreau, David, Muda, Rafał, Myer, Annalisa, Nash, Kyle, Nitschke, Jonas P., Nurse, Matthew S., de Mello, Victoria Oldemburgo, Palacios-Galvez, Maria Soledad, Pan, Yafeng, Papp, Zsófia, Pärnamets, Philip, Paruzel-Czachura, Mariola, Perander, Silva, Pitman, Michael Mark, Raza, Ali, Rêgo, Gabriel Gaudencio, Robertson, Claire E., Rodríguez-Pascual, Iván, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia Chiara, Schultner, David T., Schutte, Enid M., Scott, Andy, Skali, Ahmed, Stefaniak, Anna, Sternisko, Anni, Strickland, Brent, Thomas, Jeffrey P., Tinghög, Gustav, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete Sefa, van Rooy, Dirk, Västfjäll, Daniel, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander C, Watermeyer, Jennifer, Willardt, Robin, Wohl, Michael J. A., Wójcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin-Theresa, Zwaan, Rolf A., Boggio, Paulo S., Whillans, Ashley, Van Lange, Paul A. M., Prasad, Rajib, Onderco, Michal, O’Madagain, Cathal, Nesh-Nash, Tarik, Laguna, Oscar Moreda, Kubin, Emily, Gümren, Mert, Fenwick, Ali, Ertan, Arhan S., Bernstein, Michael J, Amara, Hanane, and Van Bavel, Jay J.

Abstract

At the beginning of 2020, COVID-19 became a global problem. Despite all the efforts to emphasize the relevance of preventive measures, not everyone adhered to them. Thus, learning more about the characteristics determining attitudinal and behavioral responses to the pandemic is crucial to improving future interventions. In this study, we applied machine learning on the multinational data collected by the International Collaboration on the Social and Moral Psychology of COVID-19 (N = 51,404) to test the predictive efficacy of constructs from social, moral, cognitive, and personality psychology, as well as socio-demographic factors, in the attitudinal and behavioral responses to the pandemic. The results point to several valuable insights. Internalized moral identity provided the most consistent predictive contribution—individuals perceiving moral traits as central to their self-concept reported higher adherence to preventive measures. Similar results were found for morality as cooperation, symbolized moral identity, self-control, open-mindedness, and collective narcissism, while the inverse relationship was evident for the endorsement of conspiracy theories. However, we also found a non-neglible variability in the explained variance and predictive contributions with respect to macro-level factors such as the pandemic stage or cultural region. Overall, the results underscore the importance of morality-related and contextual factors in understanding adherence to public health recommendations during the pandemic

Published
2022

400. Author Correction:National identity predicts public health support during a global pandemic (Nature Communications, (2022), 13, 1, (517), 10.1038/s41467-021-27668-9)

Author

Van Bavel, Jay J., Cichocka, Aleksandra, Capraro, Valerio, Sjåstad, Hallgeir, Nezlek, John B., Pavlović, Tomislav, Alfano, Mark, Gelfand, Michele J., Azevedo, Flavio, Birtel, Michèle D., Cislak, Aleksandra, Lockwood, Patricia L., Ross, Robert Malcolm, Abts, Koen, Agadullina, Elena, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Crabtree, Charles David, Cunningham, William A., De, Koustav, Ejaz, Waqas, Elbaek, Christian T., Findor, Andrej, Flichtentrei, Daniel, Franc, Renata, Gjoneska, Biljana, Gruber, June, Gualda, Estrella, Horiuchi, Yusaku, Huynh, Toan Luu Duc, Ibanez, Agustin, Imran, Mostak Ahamed, Israelashvili, Jacob, Jasko, Katarzyna, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Krouwel, André, Laakasuo, Michael, Lamm, Claus, Leygue, Caroline, Lin, Ming Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Minda, John Paul, Mitkidis, Panagiotis, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Riaño-Moreno, Julián C., Rothmund, Tobias, Santamaría-García, Hernando, Schmid, Petra C., Stoyanov, Drozdstoy, Tewari, Shruti, Todosijević, Bojan, Tsakiris, Manos, Tung, Hans H., Umbreș, Radu G., Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew, Yucel, Meltem, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Akrawi, Narin, Mdarhri, Hamza Alaoui, Amara, Hanane, Amodio, David M., Antazo, Benedict G., Apps, Matthew, Ay, F. Ceren, Ba, Mouhamadou Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Bernal-Zárate, Maria P., Bernstein, Michael, Białek, Michał, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, Cameron, C. Daryl, Carvalho, Chrissie F., Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Córdoba-Delgado, Mateo Andres, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Cypryańska, Marzena, Dabrowska, Justyna, Daniels, Michael A., Davis, Victoria H., Dayley, Pamala N., Delouvee, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Drosinou, Marianna, Dulleck, Uwe, Ekmanis, Jānis, Ertan, Arhan S., Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Farmer, Harry, Fenwick, Ali, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, Garcia-Navarro, E. Begoña, Garladinne, Prasad, Ghajjou, Oussama, Gkinopoulos, Theofilos, Gray, Kurt, Griffin, Siobhán M., Gronfeldt, Bjarki, Gümren, Mert, Gurung, Ranju Lama, Halperin, Eran, Harris, Elizabeth, Herzon, Volo, Hruška, Matej, Huang, Guanxiong, Hudecek, Matthias F.C., Isler, Ozan, Jangard, Simon, Jørgensen, Frederik J., Kachanoff, Frank, Kahn, John, Dangol, Apsara Katuwal, Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kubin, Emily, Kunnari, Anton, Kutiyski, Yordan, Laguna, Oscar, Leota, Josh, Lermer, Eva, Levy, Jonathan, Levy, Neil, Li, Chunyun, Long, Elizabeth U., Longoni, Chiara, Maglić, Marina, McCashin, Darragh, Metcalf, Alexander L., Mikloušić, Igor, El Mimouni, Soulaimane, Miura, Asako, Molina-Paredes, Juliana, Monroy-Fonseca, César, Morales-Marente, Elena, Moreau, David, Muda, Rafał, Myer, Annalisa, Nash, Kyle, Nesh-Nash, Tarik, Nitschke, Jonas P., Nurse, Matthew S., Ohtsubo, Yohsuke, Oldemburgo de Mello, Victoria, O’Madagain, Cathal, Onderco, Michal, Palacios-Galvez, M. Soledad, Palomäki, Jussi, Pan, Yafeng, Papp, Zsófia, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlović, Zoran, Payán-Gómez, César, Perander, Silva, Pitman, Michael Mark, Prasad, Rajib, Pyrkosz-Pacyna, Joanna, Rathje, Steve, Raza, Ali, Rêgo, Gabriel G., Rhee, Kasey, Robertson, Claire E., Rodríguez-Pascual, Iván, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia C., Santiago-Tovar, Natalia, Savage, David, Scheffer, Julian A., Schönegger, Philipp, Schultner, David T., Schutte, Enid M., Scott, Andy, Sharma, Madhavi, Sharma, Pujan, Skali, Ahmed, Stadelmann, David, Stafford, Clara Alexandra, Stanojević, Dragan, Stefaniak, Anna, Sternisko, Anni, Stoica, Augustin, Stoyanova, Kristina K., Strickland, Brent, Sundvall, Jukka, Thomas, Jeffrey P., Tinghög, Gustav, Torgler, Benno, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete S., Van Lange, Paul A.M., van Prooijen, Jan Willem, van Rooy, Dirk, Västfjäll, Daniel, Verkoeijen, Peter, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander Cameron, Watermeyer, Jennifer, Wetter, Erik, Whillans, Ashley, Willardt, Robin, Wohl, Michael J.A., Wójcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin Theresa, Zwaan, Rolf A., Boggio, Paulo S., Van Bavel, Jay J., Cichocka, Aleksandra, Capraro, Valerio, Sjåstad, Hallgeir, Nezlek, John B., Pavlović, Tomislav, Alfano, Mark, Gelfand, Michele J., Azevedo, Flavio, Birtel, Michèle D., Cislak, Aleksandra, Lockwood, Patricia L., Ross, Robert Malcolm, Abts, Koen, Agadullina, Elena, Aruta, John Jamir Benzon, Besharati, Sahba Nomvula, Bor, Alexander, Choma, Becky L., Crabtree, Charles David, Cunningham, William A., De, Koustav, Ejaz, Waqas, Elbaek, Christian T., Findor, Andrej, Flichtentrei, Daniel, Franc, Renata, Gjoneska, Biljana, Gruber, June, Gualda, Estrella, Horiuchi, Yusaku, Huynh, Toan Luu Duc, Ibanez, Agustin, Imran, Mostak Ahamed, Israelashvili, Jacob, Jasko, Katarzyna, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Krouwel, André, Laakasuo, Michael, Lamm, Claus, Leygue, Caroline, Lin, Ming Jen, Mansoor, Mohammad Sabbir, Marie, Antoine, Mayiwar, Lewend, Mazepus, Honorata, McHugh, Cillian, Minda, John Paul, Mitkidis, Panagiotis, Olsson, Andreas, Otterbring, Tobias, Packer, Dominic J., Perry, Anat, Petersen, Michael Bang, Puthillam, Arathy, Riaño-Moreno, Julián C., Rothmund, Tobias, Santamaría-García, Hernando, Schmid, Petra C., Stoyanov, Drozdstoy, Tewari, Shruti, Todosijević, Bojan, Tsakiris, Manos, Tung, Hans H., Umbreș, Radu G., Vanags, Edmunds, Vlasceanu, Madalina, Vonasch, Andrew, Yucel, Meltem, Zhang, Yucheng, Abad, Mohcine, Adler, Eli, Akrawi, Narin, Mdarhri, Hamza Alaoui, Amara, Hanane, Amodio, David M., Antazo, Benedict G., Apps, Matthew, Ay, F. Ceren, Ba, Mouhamadou Hady, Barbosa, Sergio, Bastian, Brock, Berg, Anton, Bernal-Zárate, Maria P., Bernstein, Michael, Białek, Michał, Bilancini, Ennio, Bogatyreva, Natalia, Boncinelli, Leonardo, Booth, Jonathan E., Borau, Sylvie, Buchel, Ondrej, Cameron, C. Daryl, Carvalho, Chrissie F., Celadin, Tatiana, Cerami, Chiara, Chalise, Hom Nath, Cheng, Xiaojun, Cian, Luca, Cockcroft, Kate, Conway, Jane, Córdoba-Delgado, Mateo Andres, Crespi, Chiara, Crouzevialle, Marie, Cutler, Jo, Cypryańska, Marzena, Dabrowska, Justyna, Daniels, Michael A., Davis, Victoria H., Dayley, Pamala N., Delouvee, Sylvain, Denkovski, Ognjan, Dezecache, Guillaume, Dhaliwal, Nathan A., Diato, Alelie B., Di Paolo, Roberto, Drosinou, Marianna, Dulleck, Uwe, Ekmanis, Jānis, Ertan, Arhan S., Etienne, Tom W., Farhana, Hapsa Hossain, Farkhari, Fahima, Farmer, Harry, Fenwick, Ali, Fidanovski, Kristijan, Flew, Terry, Fraser, Shona, Frempong, Raymond Boadi, Fugelsang, Jonathan A., Gale, Jessica, Garcia-Navarro, E. Begoña, Garladinne, Prasad, Ghajjou, Oussama, Gkinopoulos, Theofilos, Gray, Kurt, Griffin, Siobhán M., Gronfeldt, Bjarki, Gümren, Mert, Gurung, Ranju Lama, Halperin, Eran, Harris, Elizabeth, Herzon, Volo, Hruška, Matej, Huang, Guanxiong, Hudecek, Matthias F.C., Isler, Ozan, Jangard, Simon, Jørgensen, Frederik J., Kachanoff, Frank, Kahn, John, Dangol, Apsara Katuwal, Keudel, Oleksandra, Koppel, Lina, Koverola, Mika, Kubin, Emily, Kunnari, Anton, Kutiyski, Yordan, Laguna, Oscar, Leota, Josh, Lermer, Eva, Levy, Jonathan, Levy, Neil, Li, Chunyun, Long, Elizabeth U., Longoni, Chiara, Maglić, Marina, McCashin, Darragh, Metcalf, Alexander L., Mikloušić, Igor, El Mimouni, Soulaimane, Miura, Asako, Molina-Paredes, Juliana, Monroy-Fonseca, César, Morales-Marente, Elena, Moreau, David, Muda, Rafał, Myer, Annalisa, Nash, Kyle, Nesh-Nash, Tarik, Nitschke, Jonas P., Nurse, Matthew S., Ohtsubo, Yohsuke, Oldemburgo de Mello, Victoria, O’Madagain, Cathal, Onderco, Michal, Palacios-Galvez, M. Soledad, Palomäki, Jussi, Pan, Yafeng, Papp, Zsófia, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlović, Zoran, Payán-Gómez, César, Perander, Silva, Pitman, Michael Mark, Prasad, Rajib, Pyrkosz-Pacyna, Joanna, Rathje, Steve, Raza, Ali, Rêgo, Gabriel G., Rhee, Kasey, Robertson, Claire E., Rodríguez-Pascual, Iván, Saikkonen, Teemu, Salvador-Ginez, Octavio, Sampaio, Waldir M., Santi, Gaia C., Santiago-Tovar, Natalia, Savage, David, Scheffer, Julian A., Schönegger, Philipp, Schultner, David T., Schutte, Enid M., Scott, Andy, Sharma, Madhavi, Sharma, Pujan, Skali, Ahmed, Stadelmann, David, Stafford, Clara Alexandra, Stanojević, Dragan, Stefaniak, Anna, Sternisko, Anni, Stoica, Augustin, Stoyanova, Kristina K., Strickland, Brent, Sundvall, Jukka, Thomas, Jeffrey P., Tinghög, Gustav, Torgler, Benno, Traast, Iris J., Tucciarelli, Raffaele, Tyrala, Michael, Ungson, Nick D., Uysal, Mete S., Van Lange, Paul A.M., van Prooijen, Jan Willem, van Rooy, Dirk, Västfjäll, Daniel, Verkoeijen, Peter, Vieira, Joana B., von Sikorski, Christian, Walker, Alexander Cameron, Watermeyer, Jennifer, Wetter, Erik, Whillans, Ashley, Willardt, Robin, Wohl, Michael J.A., Wójcik, Adrian Dominik, Wu, Kaidi, Yamada, Yuki, Yilmaz, Onurcan, Yogeeswaran, Kumar, Ziemer, Carolin Theresa, Zwaan, Rolf A., and Boggio, Paulo S.

Abstract

In this article the author name ‘Agustin Ibanez’ was incorrectly written as ‘Augustin Ibanez’. The original article has been corrected.

Published
2022

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