11,028 results on '"A, Franzini"'
Search Results
352. The location of InsP3 receptors in Purkinje cells of murine cerebellum does not supports a direct interaction in the transfer of calcium ions between ER and mitochondria
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Ramesh Iyer and Clara Franzini-Armstrong
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IP3 receptors ,mitochondria ,cerebellum Purkinje cells ,Medicine ,Human anatomy ,QM1-695 - Abstract
The inositol-3-phosphate receptors (IP3Rs) of cerebellar Purkinje cells are located in abundant, large stacks of endoplasmic reticulum (ER) cisternae. Using thin section electron microscopy, we identify very frequent associations of the ER stacks with mitochondria. The associations have two components: a single, close ER-mitochondria contact on one side to the stack, and multiple layers of ER cisternae decorated by IP3Rs receptors on the side away from the mitochondria. Due to their location in the stacks, IP3Rs are never in contact with the mitochondria, although they are in their vicinity. We conclude that transfer of Ca2+ between ER and mitochondria is not directly mediated by IP3Rs, but is based on mitochondrial Ca2+ uptake from the local cytoplasmic spikes during IP3Rs’ activity.
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- 2021
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353. Persistent Coverage Control for Teams of Heterogeneous Agents.
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Alberto Mellone, Giovanni Franzini, Lorenzo Pollini, and Mario Innocenti
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- 2018
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354. Modeling the Flow Around Islands in Rivers Using a One-Dimensional Approach
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Franzini, Fabian, Hoedenaeken, Damien, Soares-Frazão, Sandra, Gourbesville, Philippe, editor, Cunge, Jean, editor, and Caignaert, Guy, editor
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- 2018
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355. Measurement of the Free-Surface Elevation for Flows in Complex Topography Using Photogrammetry
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d’Odeigne, Olivier Carlier, Franzini, Fabian, Da Rosa, Guilherme Coutinho Machado, Janssens, Nils, Soares-Frazão, Sandra, Gourbesville, Philippe, editor, Cunge, Jean, editor, and Caignaert, Guy, editor
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- 2018
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356. Comparing Wood versus Concrete: An Explorative Study of Municipal Civil Servants' Beliefs About Multistory Building Materials in Finland
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Franzini, Florencia, Berghall, Sami, Toppinen, Anne, and Toivonen, Ritva
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Skyscrapers -- Design and construction -- Environmental aspects ,Land use -- Planning ,Tall buildings -- Design and construction -- Environmental aspects ,Business ,Forest products industry - Abstract
The rising interest in wooden multistory buildings (WMSB) has led to multiple studies investigating how construction professionals perceive different structural frame materials. These investigations, however, exclude viewpoints from public employees (i.e., civil servants), who are central to driving the implementation of WMSB. This study is part of a broader inquiry to examine perceptions from Finnish civil servants who are responsible for municipal land-use planning and development. To this end, a questionnaire applying the theory of planned behavior was designed. Civil servants were asked to evaluate how strongly they believe WMSB possess 16 attributes in comparison to concrete multistory buildings (CMSB). The attributes constitute statements concerning various economic, social, and environmental impacts of multistory buildings, as well as technical properties. Responses (N = 273) indicate that WMSB are believed to possess positive environmental attributes and to support economic development. In contrast, CMSB are regarded to have lower construction and maintenance cost and to be less susceptible to fire. Furthermore, exogenous factors, like demographics, previous experience, and social environments, were significantly correlated to respondents' beliefs. Especially prominent was the relationship between profession and beliefs about technical and environmental attributes. Future research should focus on determining whether the set of attributes assessed in this study are relevant to the implementation of multistory building projects within Finnish municipalities., In many countries, public and private interest in the construction of wooden multistory buildings (WMSB) (1) is increasing. The emergence of WMSB stem from the adoption of science and technology [...]
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- 2021
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357. Comments on the use of ozone therapy in post-acute sequelae of COVID-19 (PASC) patients
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Chirumbolo, Salvatore, Valdenassi, Luigi, Franzini, Marianno, Richelmi, Tommaso, and Tirelli, Umberto
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- 2024
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358. Antithrombotic properties of Tafamidis: An additional protective effect for transthyretin amyloid cardiomyopathy patients
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Ministrini, Stefano, Niederberger, Rebecca, Akhmedov, Alexander, Beer, Georgia, Puspitasari, Yustina M., Franzini, Maria, Vergaro, Giuseppe, Cannie, Douglas E., Elliott, Perry, Kahr, Peter C., Hock, Christoph, Kobza, Richard, Toggweiler, Stefan, Lüscher, Thomas F., Camici, Giovanni G., and Stämpfli, Simon F.
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- 2024
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359. The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations
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Franzini, Anca, Pomicter, Anthony D., Yan, Dongqing, Khorashad, Jamshid S., Tantravahi, Srinivas K., Than, Hein, Ahmann, Jonathan M., O'Hare, Thomas, and Deininger, Michael W.
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- 2019
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360. Italien
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Becchi, Paolo, primary, Tibaldeo, Roberto Franzini, additional, and Fossa, Fabio, additional
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- 2021
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361. Large Bowel Emergencies
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Pattonieri, Vittoria, primary, Perrone, Gennaro, additional, Tarasconi, Antonio, additional, Abongwa, Hariscine K., additional, Franzini, Giacomo, additional, and Catena, Fausto, additional
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- 2021
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362. Utopie
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Franzini Tibaldeo, Roberto, primary
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- 2021
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363. CALÇOS DE MADEIRA LAMELADA COLADA (MLC) DESENVOLVIDOS A PARTIR DE RESÍDUOS DE MADEIRA DE EUCALIPTO
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Segundinho, Pedro Gutemberg de Alcântara, primary, Gonçalves, Fabricio Gomes, additional, Oliveira, José Tarcísio da Silva, additional, Oliveira, Rafael Gonçalves Espósito de, additional, Lopes, Nayara Franzini, additional, Oliveira, Ramon Ferreira, additional, Souza, Clara Gaspar Fossi de, additional, Mastela, Leonor da Cunha, additional, and Taquetti, Vinícius Borge, additional
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- 2021
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364. System-Level Overall Equipment Effectiveness for Improving Asset Management Performance: A Case Study Application
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Franzini, Alberto, primary, Polenghi, Adalberto, additional, Roda, Irene, additional, and Macchi, Marco, additional
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- 2021
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365. Hypofractionated Radiosurgery for Perioptic Meningiomas: Current Practice, Principles, and Treatment Quandary
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Franzini, Andrea, primary, Attuati, Luca, additional, Zaed, Ismail, additional, and Picozzi, Piero, additional
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- 2021
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366. Use of remote control in the intraoperative telemetry of cochlear implant: multicentric study
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Tanamati, Liege Franzini, Goffi-Gomez, Maria Valéria Schmidt, Muniz, Lilian Ferreira, Samuel, Paola Angélica, Wiemes, Gislaine Richter Minhoto, Lima, Daniele Penna, Curi, Sílvia Badur, Onuki, Lucia Cristina, Queiroz, Carla Fortunato, Capistrano, Ana Karla Bigois, Moret, Adriane Lima Mortari, Kimura, Márcia Yuri Tsumura, Oyanguren, Valeria, and Mauch, Herbert
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- 2019
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367. Neonatal Intensive Care Variation in Medicaid-Insured Newborns: A Population-Based Study
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Goodman, David C., Ganduglia-Cazaban, Cecilia, Franzini, Luisa, Stukel, Therese A., Wasserman, Jared R., Murphy, Megan A., Kim, Youngran, Mowitz, Meredith E., Tyson, Jon E., Doherty, Julie R., and Little, George A.
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- 2019
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368. Binding of Gamma-Glutamyl Transferase to TLR4 Signalling Allows Tissue Factor Activation in Monocytes
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Chiara Sanguinetti, Valentina Scalise, Tommaso Neri, Alessandro Celi, Vanessa Susini, Maria Franzini, and Roberto Pedrinelli
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tissue factor ,gamma-glutamyl transferase ,toll-like receptor 4 ,monocytes ,coagulation ,cytokine ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Gamma-glutamyl transferase (GGT) is involved in the progression of atherosclerosis, since its enzymatic activity promotes the generation of reactive oxygen species (ROS). Besides, GGT may act as a prothrombotic factor by inducing tissue factor (TF) expression, independently of its enzymatic activity. The aim of this study was to assess whether GGT-induced TF stimulation was a consequence of binding to toll-like receptor 4 (TLR4) expressed on monocytes, the precursors of macrophages and foam cells which colocalize with GGT activity within atherosclerotic plaques. Experiments were performed in human peripheral blood mononuclear cells (PBMCs), THP-1 cells (a monocytic cellular model), and HEK293 cells, which were genetically modified to study the activation of TLR4. TF procoagulant activity was assessed by a one-stage clotting time test, and TF protein expression was estimated by western blot. Human recombinant (hr) GGT protein increased TF procoagulant activity and protein expression in both PBMCs and THP-1 cells. The GGT-induced TF stimulation was prevented by cellular pretreatment with TLR4/NF-κB inhibitors (LPS-Rs, CLI-095, and BAY-11-7082), and HEK293 cells lacking TLR4 confirmed that TLR4 is essential for GGT-induced activation of NF-κB. In conclusion, hrGGT induced TF expression in monocytes through a cytokine-like mechanism that involved the activation of TLR4/NF-κB signaling.
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- 2022
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369. The Mito-Hormetic Mechanisms of Ozone in the Clearance of SARS-CoV2 and in the COVID-19 Therapy
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Salvatore Chirumbolo, Angelica Varesi, Marianno Franzini, Luigi Valdenassi, Sergio Pandolfi, Umberto Tirelli, Ciro Esposito, and Giovanni Ricevuti
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anti-inflammatory ,anti-oxidant ,COVID-19 ,PASC ,post-COVID ,ozone therapy ,Biology (General) ,QH301-705.5 - Abstract
An increasing body of evidence in the literature is reporting the feasibility of using medical ozone as a possible alternative and adjuvant treatment for COVID-19 patients, significantly reducing hospitalization time, pro-inflammatory indicators, and coagulation markers and improving blood oxygenation parameters. In addition to the well-described ability of medical ozone in counteracting oxidative stress through the upregulation of the main anti-oxidant and scavenging enzymes, oxygen–ozone (O2–O3) therapy has also proved effective in reducing chronic inflammation and the occurrence of immune thrombosis, two key players involved in COVID-19 exacerbation and severity. As chronic inflammation and oxidative stress are also reported to be among the main drivers of the long sequelae of SARS-CoV2 infection, a rising number of studies is investigating the potential of O2–O3 therapy to reduce and/or prevent the wide range of post-COVID (or PASC)-related disorders. This narrative review aims to describe the molecular mechanisms through which medical ozone acts, to summarize the clinical evidence on the use of O2–O3 therapy as an alternative and adjuvant COVID-19 treatment, and to discuss the emerging potential of this approach in the context of PASC symptoms, thus offering new insights into effective and safe nonantiviral therapies for the fighting of this devastating pandemic.
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- 2022
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370. The Journey of Human Transthyretin: Synthesis, Structure Stability, and Catabolism
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Chiara Sanguinetti, Marianna Minniti, Vanessa Susini, Laura Caponi, Giorgia Panichella, Vincenzo Castiglione, Alberto Aimo, Michele Emdin, Giuseppe Vergaro, and Maria Franzini
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transthyretin ,TTR amyloidosis ,retinol-binding protein ,thyroxine ,retinol ,TTR clearance ,Biology (General) ,QH301-705.5 - Abstract
Transthyretin (TTR) is a homotetrameric protein mainly synthesised by the liver and the choroid plexus whose function is to carry the thyroid hormone thyroxine and the retinol-binding protein bound to retinol in plasma and cerebrospinal fluid. When the stability of the tetrameric structure is lost, it breaks down, paving the way for the aggregation of TTR monomers into insoluble fibrils leading to transthyretin (ATTR) amyloidosis, a progressive disorder mainly affecting the heart and nervous system. Several TTR gene mutations have been characterised as destabilisers of TTR structure and are associated with hereditary forms of ATTR amyloidosis. The reason why also the wild-type TTR is intrinsically amyloidogenic in some subjects is largely unknown. The aim of the review is to give an overview of the TTR biological life cycle which is largely unknown. For this purpose, the current knowledge on TTR physiological metabolism, from its synthesis to its catabolism, is described. Furthermore, a large section of the review is dedicated to examining in depth the role of mutations and physiological ligands on the stability of TTR tetramers.
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- 2022
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371. Neobladder 'Function': Tips and Tricks for Surgery and Postoperative Management
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Daniela Fasanella, Michele Marchioni, Luigi Domanico, Claudia Franzini, Antonino Inferrera, Luigi Schips, and Francesco Greco
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bladder cancer ,orthotopic neobladder ,robot-assisted radical cystectomy ,urinary diversion ,complications ,continence ,Science - Abstract
Orthotopic neobladder (ONB) reconstruction is a continent urinary diversion procedure increasingly used in patients with muscle-invasive bladder cancer following radical cystectomy (RC). It represents a valid alternative to the ileal duct in suitable patients who do not prefer a stoma and are motivated to undergo adequate training of the neobladder. Careful patient selection, taking into account the absolute and relative contraindications for ONB as well as an adequate recovery protocol after surgery are integral to the success of this procedure and the oncological and functional outcomes. The objective of this review is to summarize the current data on RC with ONB in terms of patient selection, preoperative preparation, surgical techniques and functional (continence and sexual activity) and oncological outcomes, with particular attention to the management of complications and the impact on quality of life (QoL).
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- 2022
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372. Relationships of Overt and Silent Brain Lesions With Cognitive Function in Patients With Atrial Fibrillation
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Berger, Sebastian, Bernasconi, Raffaele, Fröhlich, Lorin, Göldi, Tobias, Gugganig, Rebecca, Kofler, Thomas, Krisai, Philipp, Mongiat, Michel, Pudenz, Christiane, Repilado, Javier Ruperti, Schweizer, Aleksandra, Springer, Anne, Stempfel, Samuel, Szucs, Thomas, van der Stouwe, Jan, Voellmin, Gian, Zwimpfer, Leon, Aujesky, Drahomir, Fuhrer, Juerg, Roten, Laurent, Jung, Simon, Mattle, Heinrich, Adam, Luise, Aubert, Carole Elodie, Feller, Martin, Schneider, Claudio, Loewe, Axel, Flückiger, Tanja, Groen, Cindy, Schwab, Nathalie, Beynon, Christopher, Dillier, Roger, Eberli, Franz, Fontana, Simone, Franzini, Christine, Juchli, Isabel, Liedtke, Claudia, Nadler, Jacqueline, Obst, Thayze, Schneider, Xiaoye, Studerus, Katrin, Weishaupt, Dominik, Kuest, Silke, Scheuch, Karin, Hischier, Denise, Bonetti, Nicole, Bello, Corina, Isberg, Henriette, Grau, Alexandra, Villinger, Jonas, Papaux, Mary-Monica, Baumgartner, Philipp, Filipovic, Mark, Frick, Marcel, Anesini, Adriana, Camporini, Cristina, Conte, Giulio, Caputo, Maria Luce, Regoli, Francois, Moccetti, Tiziano, Brenner, Roman, Altmann, David, Forrer, Manuela, Gemperle, Michaela, Firmann, Mathieu, Foucras, Sandrine, Berte, Benjamin, Kaeppeli, Andrea, Mehmann, Brigitta, Pfeiffer, Markus, Russi, Ian, Schmidt, Kai, Weberndoerfer, Vanessa, Young, Mabelle, Zbinden, Melanie, Vicari, Luisa, Frangi, Jane, Terrot, Tatiana, Gallet, Hervé, Guillermet, Elise, Lazeyras, Francois, Lovblad, Karl-Olof, Perret, Patrick, Teres, Cheryl, Lauriers, Nathalie, Méan, Marie, Salzmann, Sandrine, Arenja, Nisha, Grêt, Andrea, Vitelli, Sandra, Gallino, Augusto, Schoenenberger-Berzins, Renate, Witassek, Fabienne, Radue, Ernst-Wilhelm, Benkert, Pascal, Fabbro, Thomas, Simon, Patrick, Schmid, Ramun, Conen, David, Rodondi, Nicolas, Müller, Andreas, Beer, Juerg H., Ammann, Peter, Moschovitis, Giorgio, Auricchio, Angelo, Hayoz, Daniel, Kobza, Richard, Shah, Dipen, Novak, Jan, Schläpfer, Jürg, Di Valentino, Marcello, Aeschbacher, Stefanie, Blum, Steffen, Meyre, Pascal, Sticherling, Christian, Bonati, Leo H., Ehret, Georg, Moutzouri, Elisavet, Fischer, Urs, Monsch, Andreas U., Stippich, Christoph, Wuerfel, Jens, Sinnecker, Tim, Coslovsky, Michael, Schwenkglenks, Matthias, Kühne, Michael, and Osswald, Stefan
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- 2019
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373. Electroacoustic verification of frequency modulation systems in cochlear implant users
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Fidêncio, Vanessa Luisa Destro, Jacob, Regina Tangerino de Souza, Tanamati, Liége Franzini, Bucuvic, Érika Cristina, and Moret, Adriane Lima Mortari
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- 2019
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374. Threshold Determination for False Track Probability in the Multipath ML-PMHT
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Francesco A. Palmieri, Christopher Franzini, Peter Willett, Yaakov Bar Shalom, Palmieri, Francesco, Franzini, Christopher, Willett, Peter, and Shalom, Yaakov Bar
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Aerospace Engineering ,Electrical and Electronic Engineering - Published
- 2023
375. Degree of non-K\'ahlerianity for 6-dimensional nilmanifolds
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Angella, Daniele, Franzini, Maria Giovanna, and Rossi, Federico Alberto
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Mathematics - Differential Geometry ,57T15, 32Q57, 53C558 - Abstract
We use Bott-Chern cohomology to measure the non-K\"ahlerianity of 6-dimensional nilmanifolds endowed with the invariant complex structures in M. Ceballos, A. Otal, L. Ugarte, and R. Villacampa's classification, [Invariant Complex Structures on 6-Nilmanifolds: Classification, Fr\"olicher Spectral Sequence and Special Hermitian Metrics, J. Geom. Anal. (2014)]. We investigate the existence of pluriclosed metric in connection with such a classification.
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- 2012
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376. Verba Bestiae: How Latin Conquered Heavy Metal
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Cecchini, Flavio M., primary, Franzini, Greta H., additional, and Passarotti, Marco C., additional
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- 2020
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377. Goethe in Italien: Auf Reisen mit Winckelmann
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Franzini, Elio, primary
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- 2020
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378. Fragmentos de infância lançados ao vento
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FRANZINI, J. F., primary
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- 2020
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379. O PROGRAMA BOLSA FAMÍLIA E OS POVOS INDÍGENAS DA AMAZÔNIA: Os índios são “pobres”?
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FRANZINI, J. F., primary
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- 2020
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380. Pathophysiology of Cardiac Amyloidosis
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Morfino, Paolo, Aimo, Alberto, Franzini, Maria, Vergaro, Giuseppe, Castiglione, Vincenzo, Panichella, Giorgia, Limongelli, Giuseppe, and Emdin, Michele
- Abstract
Amyloidosis refers to a heterogeneous group of disorders sharing common pathophysiological mechanisms characterized by the extracellular accumulation of fibrillar deposits consisting of the aggregation of misfolded proteins. Cardiac amyloidosis (CA), usually caused by deposition of misfolded transthyretin or immunoglobulin light chains, is an increasingly recognized cause of heart failure burdened by a poor prognosis. CA manifests with a restrictive cardiomyopathy which progressively leads to biventricular thickening, diastolic and then systolic dysfunction, arrhythmias, and valvular disease. The pathophysiology of CA is multifactorial and includes increased oxidative stress, mitochondrial damage, apoptosis, impaired metabolism, and modifications of intracellular calcium balance.
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- 2024
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381. Digital Editions of Text: Surveying User Requirements in the Digital Humanities.
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Greta Franzini, Melissa Terras, and Simon Mahony
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- 2019
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382. Intracranial Sonodynamic Therapy With 5-Aminolevulinic Acid and Sodium Fluorescein: Safety Study in a Porcine Model
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Luca Raspagliesi, Antonio D’Ammando, Matteo Gionso, Natasha D. Sheybani, Maria-Beatriz Lopes, David Moore, Steven Allen, Jeremy Gatesman, Edoardo Porto, Kelsie Timbie, Andrea Franzini, Francesco Di Meco, Jason Sheehan, Zhiyuan Xu, and Francesco Prada
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safety ,brain tumors ,ultrasound ,sonodynamic therapy (SDT) ,fluorescein (FL) ,fluorescein 5-aminolevulinic acid (5-ALA) ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
BackgroundSonodynamic therapy (SDT) is an emerging ultrasound-based treatment modality for malignant gliomas which combines ultrasound with sonosensitizers to produce a localized cytotoxic and modulatory effect. Tumor-specificity of the treatment is achieved by the selective extravasation and accumulation of sonosensitizers in the tumor-bearing regions. The aim of this study is to demonstrate the safety of low-intensity ultrasonic irradiation of healthy brain tissue after the administration of FDA-approved sonosensitizers used for SDT in experimental studies in an in vivo large animal model.MethodsIn vivo safety of fluorescein (Na-Fl)- and 5 aminolevulinic acid (5-ALA)-mediated low-intensity ultrasound irradiation of healthy brain parenchyma was assessed in two sets of four healthy swine brains, using the magnetic resonance imaging (MRI)-guided Insightec ExAblate 4000 220 kHz system. After administration of the sonosensitizers, a wide fronto-parietal craniotomy was performed in pig skulls to allow transmission of ultrasonic beams. Sonication was performed on different spots within the thalamus and periventricular white matter with continuous thermal monitoring. Sonication-related effects were investigated with MRI and histological analysis.ResultsPost-treatment MRI images acquired within one hour following the last sonication, on day one, and day seven did not visualize any sign of brain damage. On histopathology, no signs of necrosis or apoptosis attributable to the ultrasonic treatments were shown in target areas.ConclusionsThe results of the present study suggest that either Na-FL or 5-ALA-mediated sonodynamic therapies under MRI-guidance with the current acoustic parameters are safe towards healthy brain tissue in a large in vivo model. These results further support growing interest in clinical translation of sonodynamic therapy for intracranial gliomas and other brain tumors.
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- 2021
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383. Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study
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Nepogodiev, Dmitri, Siaw-Acheampong, Kwabena, Benson, Ruth A., Bywater, Edward, Chaudhry, Daoud, Dawson, Brett E., Evans, Jonathan P., Glasbey, James C., Gujjuri, Rohan R., Heritage, Emily, Jones, Conor S., Kamarajah, Sivesh K., Khatri, Chetan, Khaw, Rachel A., Keatley, James M., Knight, Andrew, Lawday, Samuel, Li, Elizabeth, Mann, Harvinder S., Marson, Ella J., McLean, Kenneth A., Mckay, Siobhan C., Mills, Emily C., Pellino, Gianluca, Picciochi, Maria, Taylor, Elliott H., Tiwari, Abhinav, Simoes, Joana FF., Trout, Isobel M., Venn, Mary L., Wilkin, Richard JW., Bhangu, Aneel, Abbott, Tom EF., Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O., Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Alshryda, Sattar, Arnaud, Alexis P., Augestad, Knut Magne, Ayasra, Faris, Azevedo, José, Bankhead-Kendall, Brittany K., Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Minaya-Bravo, Ana, Breen, Kerry A., Bretherton, Chris, Buarque, Igor Lima, Burke, Joshua, Caruana, Edward J., Chaar, Mohammad, Chakrabortee, Sohini, Christensen, Peter, Cox, Daniel, Cukier, Moises, Cunha, Miguel F., Davidson, Giana H., Desai, Anant, Di Saverio, Salomone, Drake, Thomas M., Edwards, John G., Elhadi, Muhammed, Emile, Sameh, Farik, Shebani, Fiore, Marco, Fitzgerald, J Edward, Ford, Samuel, Garmanova, Tatiana, Gallo, Gaetano, Ghosh, Dhruva, Ataíde Gomes, Gustavo Mendonça, Grecinos, Gustavo, Griffiths, Ewen A., Gruendl, Magdalena, Halkias, Constantine, Harrison, Ewen M., Hisham, Intisar, Hutchinson, Peter J., Hwang, Shelley, Isik, Arda, Jenkinson, Michael D., Jonker, Pascal, MA Kaafarani, Haytham, Keller, Debby, Kolias, Angelos, Kruijff, Schelto, Lawani, Ismail, Lederhuber, Hans, Leventoglu, Sezai, Litvin, Andrey, Loehrer, Andrew, Löffler, Markus W., Lorena, Maria Aguilera, Modolo, Maria Marta, Major, Piotr, Martin, Janet, Mashbari, Hassan N., Mazingi, Dennis, Metallidis, Symeon, Mohan, Helen M., Moore, Rachel, Moszkowicz, David, Moug, Susan, Ng-Kamstra, Joshua S., Maimbo, Mayaba, Negoi, Ionut, Niquen, Milagros, Ntirenganya, Faustin, Olivos, Maricarmen, Oussama, Kacimi, Outani, Oumaima, Parreno-Sacdalanm, Marie Dione, Pata, Francesco, Perez Rivera, Carlos Jose, Pinkney, Thomas D., van der Plas, Willemijn, Pockney, Peter, Qureshi, Ahmad, Radenkovic, Dejan, Ramos-De la Medina, Antonio, Richards, Toby, Roberts, Keith, Roslani, April C., Rutegård, Martin, Segura-Sampedro, Juan José, Santos, Irène, Satoi, Sohei, Sayyed, Raza, Schache, Andrew, Schnitzbauer, Andreas A., Seyi-Olajide, Justina O., Sharma, Neil, Shaw, Catherine A., Shaw, Richard, Shu, Sebastian, Soreide, Kjetil, Spinelli, Antonino, Stewart, Grant D., Sund, Malin, Sundar, Sudha, Tabiri, Stephen, Townend, Philip, Tsoulfas, Georgios, van Ramshorst, Gabrielle H., Vidya, Raghavan, Vimalachandran, Dale, Warren, Oliver J., Wedderburn, Duane, Wright, Naomi, Booth, Lesley, Barker, Neil, Cooke, Shirley, Doré, Suzanne, Horwood, Nigel, Runigamugabo, Emmy, Weir, Carrie Tierney, Dajti I, Albania, C, Allemand, LA, Boccalatte, M, Figari, M, Lamm, J, Larrañaga, C, Marchitelli, F, Noll, D, Odetto, M, Perrotta, J, Saadi, L, Zamora, Ballester, A.M., KE, Tapper, N, Zeff, JI, Valenzuela, C, Alurralde, J, Anastasio, Perez de Nucci A, Apas, EL, Caram, D, Eskinazi, JP, Mendoza, M, Usandivaras, R, Badra, A, Esteban, JS, García, PM, García, JI, Gerchunoff, Lucchini, S.M., NIgra, M.A., L, Vargas, T, Hovhannisyan, A, Stepanyan, CE, Vasey, EGR, Watson, C, Ip, J, Kealey, CSH, Lim, S, Sengupta, S, Ward, E, Wong, T, Gould, R, Gourlay, B, Griffiths, S, Gananadha, M, McLaren, J, Cecire, N, Joshi, S, Salindera, A, Sutherland, JH, Ahn, G, Charlton, S, Chen, N, Gauri, R, Hayhurst, S, Jang, F, Jia, C, Mulligan, W, Yang, G, Ye, H, Zhang, M, Ballal, D, Gibson, D, Hayne, H, McMillan, J, Moss, MJ, Pugliese, T, Richards, YTN, Seow, A, Thian, P, Viswambaram, UG, Vo, J, Bennetts, T, Bright, Brooke-Smith, M., R, Fong, B, Gricks, L, Huang, YH, 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M, Mohammed, G, Tahhan, V, Valtzoglou, N, Blencowe, P, Eskander, K, Gash, L, Gourbault, M, Hanna, TA, Maccabe, B, Main, J, Olivier, C, Newton, S, Roswadowski, N, Ryan, E, Teh, D, West, H, Al-omishy, M, Baig, H, Bates, Taranto G, Di, K, Dickson, N, Dunne, C, Gill, D, Howe, D, Jeevan, A, Khajuria, Martin-Ucar, A., K, McEvoy, P, Naredla, S, Robertson, M, Sait, DR, Sarma, S, Shanbhag, T, Shortland, S, Simmonds, J, Skillman, N, Tewari, G, Walton, Akhtar, M.A., A, Brunt, J, McIntyre, K, Milne, MM, Rashid, A, Sgrò, KE, Stewart, A, Turnbull, Abou-Foul, A.K., G, Gossedge, S, O’Donnell, F, Oldfield, S, Thomson, Gonzalez M, Aguilar, S, Talukder, C, Boyle, D, Fernando, K, Gallagher, A, Laird, D, Tham, M, Bath, P, Basnyat, H, Davis, P, Montauban, A, Shrestha, K, Agarwal, T, Arif, C, Magee, T, Nambirajan, S, Powell, R, Vinayagam, I, Flindall, A, Hanson, V, Mahendran, S, Green, M, Lim, L, MacDonald, V, Miu, L, Onos, K, Sheridan, R, Young, F, Alam, O, Griffiths, C, Houlden, VS, Kolli, AK, Lala, S, Leeson, R, Peevor, Z, Seymour, E, Consorti, R, Gonzalez, R, Grolman, Kwan-Feinberg, R., T, Liu, O, Merzlikin, Francisco, San, A, Brown, Z, Cooper, S, Hirji, J, Jolissaint, D, Mahvi, B, Okafor, CP, Raut, V, Roxo, A, Salim, S, Bessen, L, Chen, L, Dagrosa, K, Fay, C, Fleischer, R, Hasson, E, Henderson, M, Leech, A, Loehrer, C, Markey, J, Paydarfar, K, Rosenkranz, K, Telma, N, Tocci, Wilkinson-Ryan, I., M, Bokenkamp, K, Brown, D, Fleming, C, Heron, C, Hill, H, Kay, E, Leede, K, McElhinney, KA, Olson, EC, Osterberg, C, Riley, P, Srikanth, J, Barbour, D, Blazer, GA, DiLalla, O, Fayanju, ES, Hwang, R, Kahmke, H, Kazaure, A, Lazarides, W, Lee, M, Lidsky, C, Menendez, D, Moris, J, Plichta, MC, Pradhan, L, Puscas, HE, Rice, D, Rocke, L, Rosenberger, R, Scheri, Smith, B.D., Stang, M.T., L, Tolnitch, K, Turnage, J, Visgauss, FS, Walton, T, Watts, S, Zani, J, Farma, K, Cardona, MC, Russell, J, Clark, D, Kwon, N, Goel, J, Kronenfeld, B, Bigelow, E, Etchill, Gabre-Kidan, A., H, Jenny, A, Kent, MR, Ladd, C, Long, H, Malapati, A, Margalit, S, Rapaport, J, Rose, K, Stevens, L, Tsai, D, Vervoort, P, Yesantharao, A, Dehal, D, Klaristenfeld, K, Huynh, H, Kaafarani, L, Naar, M, Qadan, L, Brown, I, Ganly, JE, Mullinax, N, Alpert, C, Gillezeau, Miles DDS MD, F.A.C.S.B.A., E, Taioli, DE, Cha, E, Gleeson, C, Horn, U, Sarpel, N, Gusani, J, Hazelton, J, Maines, JS, Oh, A, Ssentongo, P, Ssentongo, A, Bhama, K, Colling, M, Najarian, M, Azam, A, Choudhry, W, Marx, Y, Abedin, G, Arzumanov, R, Chokshi, S, Gabrilovich, N, Glass, E, Kalyoussef, Parvin-Nejad, F.P., D, Roden, J, Stein, Suarez-Ligon, A., G, Tsui, K, Zhao, J, Fleming, A, Fuson, J, Gigliotti, A, Ovaitt, Y, Ying, MK, Abel, V, Andaya, K, Bigay, Boeck, M.A., H, Chern, C, Corvera, El-Sayed, I., A, Glencer, P, Ha, Hamilton, B.C.S., C, Heaton, K, Hirose, Jablons, D.M., KS, Kirkwood, LZ, Kornblith, JR, Kratz, RH, Lee, PN, Miller, EK, Nakakura, Nunez-Garcia, B., RJ, O’Donnell, D, Ozgediz, P, Park, B, Robinson, A, Sarin, B, Sheu, MG, Varma, KC, Wai, R, Wustrack, MJ, Xu, M, Zimel, D, CA) Beswick, J, Goddard, J, Manor, J, Song, Springs/Loveland, Denver/Colorado, A, Cioci, W, Pavlis, K, Rakoczy, G, Ruiz, R, Saberi, T, Fullmer, C, Gaskill, N, Gross, K, Kiong, CL, Roland, SN, Zafar, M, Abdallah, A, Abouassi, E, Aigbivbalu, M, Almasri, J, Eid, B, George, G, Kulkarni, H, Marwan, M, Mehdi, Andrés M, San, J, Sundaresan, SG, Aoun, VS, Ban, HH, Batjer, K, Bosler, J, Caruso, B, Sumer, D, Abbott, A, Acher, T, Aiken, J, Barrett, E, Foley, PB, Schwartz, AT, Hawkins, A, Maiga, NM, Ruzgar, M, Sion, S, Ullrich, J, Laufer, S, Scasso, Al-Naggar, H., Al-Shehari, M., A, Almassaudi, M, Alsayadi, R, Alsayadi, M, Nahshal, S, Shream, S, AL-Ameri, M, Aldawbali, Fotopoulou, Christina, Khan, Tabassum, Bracinik, Juraj, Glasbey, James, Abu-Rustum, Nadeem, Chiva, Luis, Fagotti, Anna, Fujiwara, Keiichi, Ghebre, Rahel, Gutelkin, Murat, Konney, Thomas O., Ng, Joseph, Pareja, Rene, Kottayasamy Seenivasagam, Rajkumar, Sehouli, Jalid, Surappa, Shylasree T.S., and Leung, Elaine
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- 2022
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384. Mining and analysing one billion requests to linguistic services.
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Marco Büchler, Greta Franzini, Emily Franzini, and Thomas Eckart
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- 2016
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385. Why Worry About the Super-Rich? The Reasons and Possible Remedies
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Franzini, Maurizio, Granaglia, Elena, Raitano, Michele, Franzini, Maurizio, Granaglia, Elena, and Raitano, Michele
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- 2016
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386. Extreme Inequality, Well-Being, Freedom
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Franzini, Maurizio, Granaglia, Elena, Raitano, Michele, Franzini, Maurizio, Granaglia, Elena, and Raitano, Michele
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- 2016
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387. The Super-Rich: A Matter of Desert?
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Franzini, Maurizio, Granaglia, Elena, Raitano, Michele, Franzini, Maurizio, Granaglia, Elena, and Raitano, Michele
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- 2016
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388. The Planet of the Rich: An Exploration
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Franzini, Maurizio, Granaglia, Elena, Raitano, Michele, Franzini, Maurizio, Granaglia, Elena, and Raitano, Michele
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- 2016
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389. The Super-Rich, Competition and Power
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Franzini, Maurizio, Granaglia, Elena, Raitano, Michele, Franzini, Maurizio, Granaglia, Elena, and Raitano, Michele
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- 2016
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390. Energy measurements by means of transition radiation in novel Linacs
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Marongiu, M., Castellano, M., Chiadroni, E., Cianchi, A., Franzini, G., Giribono, A., Mostacci, A., Palumbo, L., Shpakov, V., Stella, A., and Variola, A.
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- 2018
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391. Parental and Peer Factors Associated with Body Image Discrepancy among Fifth-Grade Boys and Girls
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Michael, Shannon L, Wentzel, Kathryn, Elliott, Marc N, Dittus, Patricia J, Kanouse, David E, Wallander, Jan L, Pasch, Keryn E, Franzini, Luisa, Taylor, Wendell C, Qureshi, Tariq, Franklin, Frank A, and Schuster, Mark A
- Subjects
Mental Health ,Prevention ,Behavioral and Social Science ,Nutrition ,Clinical Research ,Pediatric ,Obesity ,Body Image ,Bullying ,Child ,Female ,Health Surveys ,Humans ,Male ,Models ,Psychological ,Models ,Statistical ,Parent-Child Relations ,Peer Group ,Self Concept ,Sex Factors ,United States ,Body image discrepancy ,Peer factors ,Parental factors ,Self-worth ,Fifth graders ,Specialist Studies in Education ,Psychology ,Developmental & Child Psychology - Abstract
Many young adolescents are dissatisfied with their body due to a discrepancy between their ideal and actual body size, which can lead to weight cycling, eating disorders, depression, and obesity. The current study examined the associations of parental and peer factors with fifth-graders' body image discrepancy, physical self-worth as a mediator between parental and peer factors and body image discrepancy, and how these associations vary by child's sex. Body image discrepancy was defined as the difference between young adolescents' self-perceived body size and the size they believe a person their age should be. Data for this study came from Healthy Passages, which surveyed 5,147 fifth graders (51 % females; 34 % African American, 35 % Latino, 24 % White, and 6 % other) and their primary caregivers from the United States. Path analyses were conducted separately for boys and girls. The findings for boys suggest father nurturance and getting along with peers are related negatively to body image discrepancy; however, for girls, fear of negative evaluation by peers is related positively to body image discrepancy. For both boys and girls, getting along with peers and fear of negative evaluation by peers are related directly to physical self-worth. In addition, mother nurturance is related positively to physical self-worth for girls, and father nurturance is related positively to physical self-worth for boys. In turn, physical self-worth, for both boys and girls, is related negatively to body image discrepancy. The findings highlight the potential of parental and peer factors to reduce fifth graders' body image discrepancy.
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- 2014
392. Supramaximal resection: retrospective study on IDH-wildtype Glioblastomas based on the new RANO-Resect classification.
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Tropeano, Maria Pia, Raspagliesi, Luca, Bono, Beatrice Claudia, Baram, Ali, Rossini, Zefferino, Franzini, Andrea, Navarria, Pierina, Clerici, Elena, Bellu, Luisa, Simonelli, Matteo, Scorsetti, Marta, Riva, Marco, Politi, Letterio Salvatore, and Pessina, Federico
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GLIOBLASTOMA multiforme ,OVERALL survival ,PROGRESSION-free survival ,INVERSE relationships (Mathematics) ,CLASSIFICATION - Abstract
Background: The prognostic value of the extent of resection in the management of Glioblastoma is a long-debated topic, recently widened by the 2022 RANO-Resect Classification, which advocates for the resection of the non-enhancing disease surrounding the main core of tumors (supramaximal resection, SUPR) to achieve additional survival benefits. We conducted a retrospective analysis to corroborate the role of SUPR by the RANO-Resect Classification in a single center, homogenous cohort of patients. Methods: Records of patients operated for WHO-2021 Glioblastomas at our institution between 2007 and 2018 were retrospectively reviewed; volumetric data of resected lesions were computed and classified by RANO-Resect criteria. Survival and correlation analyses were conducted excluding patients below near-total resection. Results: 117 patients met the inclusion criteria, encompassing 45 near-total resections (NTR), 31 complete resections (CR), and 41 SUPR. Median progression-free and overall survival were 11 and 15 months for NTR, 13 and 17 months or CR, 20 and 24 months for SUPR, respectively (p < 0.001), with inverse correlation observed between survival and FLAIR residual volume (r -0.28). SUPR was not significantly associated with larger preoperative volumes or higher rates of postoperative deficits, although it was less associated with preoperative neurological deficits (OR 3.37, p = 0.003). The impact of SUPR on OS varied between MGMT unmethylated (HR 0.606, p = 0.044) and methylated (HR 0.273, p = 0.002) patient groups. Conclusions: Results of the present study support the validity of supramaximal resection by the new RANO-Resect classification, also highlighting a possible surgical difference between tumors with methylated and unmethylated MGMT promoter. [ABSTRACT FROM AUTHOR]
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- 2024
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393. Impact of Multiple Sclerosis Subtypes on Pain Management in Patients With Trigeminal Neuralgia After Stereotactic Radiosurgery: An International Multicenter Analysis.
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De Nigris Vasconcellos, Fernando, Mashiach, Elad, Alzate, Juan Diego, Bernstein, Kenneth, Rotman, Lauren, Levy, Sarah, Qu, Tanxia, Wegner, Rodney E., Shepard, Matthew J., Patel, Samir, Warnick, Ronald E., Moreno, Nuria Martínez, Martínez Álvarez, Roberto, Picozzi, Piero, Franzini, Andrea, Peker, Selçuk, Samanci, Yavuz, Elguindy, Ahmed N., Palmer, Joshua D., and Lunsford, L. Dade
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- 2024
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394. Whole-Body Cryostimulation in Multiple Sclerosis: A Scoping Review.
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Alito, Angelo, Fontana, Jacopo Maria, Franzini Tibaldeo, Eleonora, Verme, Federica, Piterà, Paolo, Miller, Elzbieta, Cremascoli, Riccardo, Brioschi, Andrea, and Capodaglio, Paolo
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MULTIPLE sclerosis ,YOUNG adults ,FATIGUE (Physiology) ,ENDOCRINE system ,FUNCTIONAL status ,NEUROREHABILITATION - Abstract
Multiple sclerosis (MS) is the most common cause of non-traumatic long-term disability in young adults. Whole-body cryostimulation (WBC) is a cold-based physical therapy known to induce physiological exercise-mimicking changes in the cardiovascular, neuromuscular, immune, and endocrine systems and to influence functional and psychological parameters by exposing the human body to cryogenic temperatures (≤−110 °C) for 2–3 min. The purpose of this scoping review is to present an overall view on the potential role of WBC as an adjuvant therapy in the treatment of MS. PubMed, ScienceDirect, Embase, and Web of Science were searched up to 30 November 2023, and a total of 13 articles were included. WBC may have beneficial antioxidant effects as a short-term adjuvant treatment in MS. There were no significant changes in antioxidant enzymes, nitric oxide levels, metalloproteinase levels, blood counts, rheology, and biochemistry. WBC can lead to a reduction in fatigue and an improvement in functional status, with a significant effect on both mental and physical well-being. There were no reported adverse effects. The results suggest that WBC may complement therapeutic options for patients with MS, as the effects of cryogenic cold stimulation have been shown to activate antioxidant processes and improve functional status, mood, anxiety, and fatigue. [ABSTRACT FROM AUTHOR]
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- 2024
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395. The wisdom of language: an enquiry into the origins, meaning and present-day relevance of 'responsibility'.
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Franzini Tibaldeo, Roberto
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RESPONSIBILITY , *WISDOM , *ETYMOLOGY , *LINGUISTICS , *COMPREHENSION - Abstract
In this article I endeavour to clarify the meaning of 'responsibility', which in the last decades has become a cornerstone of the ethical and political debate. To this end, I carry out an etymological enquiry into this notion with respect to antique and modern European languages. The thesis I argue is that language evidences a unique capacity to cherish, nurture, and foresee with a touch of wisdom an inexhaustible repertoire of existential meanings, which take the stage in human endeavours. As a result, this enquiry helps to understand the original relational and future-oriented significance of 'responsibility'. Additionally, the analysis steers clear of incorrect or incomplete interpretations, as well as of those willing to deal with the complex and multifaced meaning of 'responsibility' in a purely logical-analytical way, which results in moving to the background, if not disregarding altogether, its historical and linguistic stratifications, which are in fact relevant to the full comprehension of this notion. [ABSTRACT FROM AUTHOR]
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- 2024
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396. Expanding safety boundaries in pediatric robotic-assisted laparoscopic surgery: are we protecting our children?
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Franzini, Stefania, Querciagrossa, Stefania, Brebion, Myriam, Lapenta, Cristina, Blanc, Thomas, and Orliaguet, Gilles
- Abstract
Little is known about the effects of CO
2 insufflation (CDI) on cerebral oxygen saturation (CrSO2 ) during laparoscopy in the pediatric population. In children undergoing robotic-assisted laparoscopic pyeloplasty (RALP), we prospectively assessed the effects of CDI using standard monitoring and cerebral near-infrared spectroscopy (NIRS). We also explored whether a correlation existed between CrSO2 and parameters known to affect cerebral blood flow. Between January 2021 and September 2023, a cohort of consecutive children older than 2 years underwent RALP at Necker-Enfants Malades Hospital in Paris. A ventilation protocol aimed to prevent hypercarbia was implemented. Data collected included standard monitoring parameters and CrSO2 by NIRS. Thirty patients (16 females), mean age 5.5 ± 3.9 (2.0–9.5) years, were included. Twenty-three patients underwent a retroperitoneal approach. The mean baseline CrSO2 value was 83.0 ± 9.8. Mean CrSO2 decreased during progressive CDI, never below baseline values, while standard-monitoring parameters did not significantly change. No significant correlation was detected between CrSO2 and end tidal CO2 , or between CrSO2 and mean arterial pressure, at any operative time. During RALP, a gradual CDI doesn’t cause pathological derangements of CrSO2 . The lack of correlation between CrSO2 and standard parameters affecting cerebral blood flow suggests the likely presence of cerebral autoregulation in our population. [ABSTRACT FROM AUTHOR]- Published
- 2024
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397. Efficacy of oxygen-ozone therapy against the pro-necrotic action of Loxosceles rufescens toxic bite
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Valdenassi, Luigi, Franzini, Marianno, Ricevuti, Giovanni, Tirelli, Umberto, Carlo Galoforo, Antonio, Vaiano, Francesco, and Chirumbolo, Salvatore
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- 2024
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398. Immune checkpoint inhibition and single fraction stereotactic radiosurgery in brain metastases from non-small cell lung cancer: an international multicenter study of 395 patients
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Lehrer, Eric J., primary, Khosla, Atulya A., additional, Ozair, Ahmad, additional, Gurewitz, Jason, additional, Bernstein, Kenneth, additional, Kondziolka, Douglas, additional, Niranjan, Ajay, additional, Wei, Zhishuo, additional, Lunsford, L. Dade, additional, Mathieu, David, additional, Trudel, Claire, additional, Deibert, Christopher P., additional, Malouff, Timothy D., additional, Ruiz-Garcia, Henry, additional, Peterson, Jennifer L., additional, Patel, Samir, additional, Bonney, Phillip, additional, Hwang, Lindsay, additional, Yu, Cheng, additional, Zada, Gabriel, additional, Picozzi, Piero, additional, Franzini, Andrea, additional, Attuati, Luca, additional, Prasad, Rahul N., additional, Raval, Raju R., additional, Palmer, Joshua D., additional, Lee, Cheng-chia, additional, Yang, Huai-che, additional, Fakhoury, Kareem R., additional, Rusthoven, Chad G., additional, Dickstein, Daniel R., additional, Sheehan, Jason P., additional, Trifiletti, Daniel M., additional, and Ahluwalia, Manmeet S., additional
- Published
- 2023
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399. Theoretically Predicted and Experimentally Detected Chirality of Dibenzocyclooctynes and Their Triazole Adducts with Azides
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Mazzoccanti, Giulia, primary, Franzini, Roberta, additional, Ciogli, Alessia, additional, Pierini, Marco, additional, Buonsenso, Fabio, additional, Faggi, Cristina, additional, Francioso, Antonio, additional, Manetto, Simone, additional, and Villani, Claudio, additional
- Published
- 2023
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400. Deep-Water Floating Offshore Wind Turbine Concept for Subsea Water Injection
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Simos, A. N., additional, Salles, M. B., additional, Monaro, R. M., additional, Martins, M. R., additional, Mas-Soler, J., additional, Gay, A., additional, Franzini, G. R., additional, Carmo, B. S., additional, Pesce, C. P., additional, Morishita, H. M., additional, Carvalho, D. F., additional, Amaral, G. A., additional, Lima, B. C., additional, Terra, L. S., additional, and Harger, A., additional
- Published
- 2023
- Full Text
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