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Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Atomic & Molecular Physics (1000-0364) is the property of Journal of Atomic & Molecular Physics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的总结肿块型肝内胆管细胞癌（IMCC)的磁共振（MRI)图像特点，探讨MRI检查在IMCC诊断中的 效能。方法收集28例IMCC患者的MRI平扫图像及动态增强扫描图像，分析图像特点，计算MRI平扫及动态 增强扫描的定性诊断符合率。结果 28例IMCC病灶MRI平扫呈T\WI低信号、T2WI混杂高信号,DWI高信号; 病灶直径为(7.4 ±2.3)cm，多呈分叶状或不规则状(19/28),边缘多不清晰，以跨叶生长为主（17/28);周围胆管扩 张、肝包膜凹陷、子灶及淋巴结肿大等征象多见,其中伴邻近包膜凹陷10例，伴周围胆管扩张13例,伴子灶11例, 伴有肝门或腹膜后等区淋巴结肿大11例;延迟强化或持续强化为其主要动态增强方式（26/28)。28例IMCC单依 靠MRI平扫图像做出诊断的定性符合率为53. 5% ,联合MRI动态增强扫描图像后定性诊断符合率提高到85.7%。 结论IMCC病灶MRI平扫 T1 WI 混杂低信号,T2WI混杂略高或高信号;MRI动态增强扫描呈向心性延迟强化或 持续强化为主,DWI呈高信号，常伴子灶、肝包膜凹陷、外围胆管扩张及肝门或腹膜后淋巴结肿大等。MRI平扫联 合动态增强扫描能够提高IMCC的诊断准确率。 [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of ulinastatin on the serum level of cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2) and phospholipase A2 (PLA2) in the patients with chronic obstructive pulmonary disease (COPD) combined with respiratory failure. Methods: 80 patients with COPD were randomly selected in our hospital from January 2014 to January 2015 and divided into two groups that 40 cases in the experimental group and 40 cases in the control group. The control group was given routine treatment, and the experimental group was given ulinastatin treatment. Then the levels of COX-2, PGE2 and PLA2 in the two groups were detected and compared before and after the treatment. Results: After treatment, the levels of COX-2, PGE2 and PLA2 in the two groups were significantly lower than before treatment (P<0.05), and the experimental group was significantly lower than that of the control group (P<0.05). After the treatment, the FEV1 and FVC were significantly better in the experimental group than those of the control group (P<0.05). Conclusions: Ulinastatin can significantly reduce the serum levels of COX-2, PGE2 and PLA2 in the patients with COPD combined with respiratory failure, and effectively improve inflammatory reaction, cell damage and clinical symptoms of the patients, which can provide a new idea for efficient treatment of COPD in clinic. [ABSTRACT FROM AUTHOR]

目的 分析总结4～6岁儿童体检中血小板计数升高的原因。 方法 回顾性分析2012年7月至2015年7月在该院体检中心进行体检的1 765例血小板增多症患儿的临床资料，检测血常规，观察血小板计数变化，分析血小板计数升高的原因。 结果 694例血小板计数升高患儿中，感染性疾病占75.8%，营养性缺铁性贫血占18.6%，原发性血小板减少性紫癜（ITP）治疗恢复期占2.7%，皮肤黏膜淋巴结综合征占1.3%，原发性血小板增多症占1.0%，急性白血病化疗缓解期占0.3%，传染性单核细胞增多症占0.1%，慢性粒细胞白血病占0.1%。 结论 临床上引起4～6岁儿童血小板计数升高的原因主要由感染、贫血、肿瘤、药物等继发性因素引起，原发性因素所占比例较低。 [ABSTRACT FROM AUTHOR]

In view of the large-scale use of antiviral drugs and the retention of drug residues and metabolites in natural water environment, potential risks of antiviral drugs to ecology environment are explored from the aspects of drug metabolism, environmental transformation, and their removal effects in sewage treatment. Single or combined treatment systems of membrane bioreactors, activated sludge processes, chlorination disinfection, ozone oxidation, and stabilization tanks are compared. The review removal rate of antiviral drugs in sewage treatment plants in different regions and different progress in research of removing antiviral drugs and proposes preventive measures and coping strategies for antiviral drugs are summarized. [ABSTRACT FROM AUTHOR]

Gastric-type endocervical adenocarcinoma （G-EAC） is the most common non-HPV-related cervical adenocarcinoma.The pathogenesis of the disease is currently unclear.G-EAC has a high degree of malignancy, and develops rapidly with non-specific clinical manifestations, hidden lesions and the poor prognosis.There is no relationship between G-EAC and HPV infection, therefore it’s difficult to detect by routine cervical cancer screening, and it’s easy to be misdiagnosed or never diagnosed. Compared with HPV-positive cervical cancer, the screening methods for this disease are limited, and early diagnosis is very difficult. In this paper, the diagnosis and treatment process of a G-EAC patient was reviewed, combined with literature review and Chinese expert consensus on the clinical diagnosis and treatment of GEAC. The clinical manifestations and the current situation of diagnosis and treatment was analyzed, which indicates the importance of gynecological examination and tertiary diagnosis and treatment procedures. [ABSTRACT FROM AUTHOR]

Objective To compare the effects of different levels of serum luteinizing hormone （LH） on the day of antagonist addition on the pregnancy outcomes of infertile patients undergoing in vitro fertilization-embryo transfer （IVF-ET） with gonadotropin-releasing hormone antagonist （GnRH-ant） flexible protocol. Methods Totally 607 infertile patients receiving antagonist flexible protocol treatment were divided into the group A of 189 cases with LH<10 mIU/mL, group B of 285 cases with 10 mIU/mL ≤ LH<20 mIU/mL, and group C of 133 cases with LH ≥ 20 mIU/mL according to the serum LH level on the day of antagonist addition. We observed and recorded the number of oocytes obtained, oocytes maturation rate, 2PN fertilization rate, the cleavage rate, high-quality embryo rate, fresh embryo implantation rate, fresh cycle transfer rate, clinical pregnancy rate, miscarriage rate, and live birth rate in patients of three groups. Results Compared with patients in the group A, the patients in the group B had higher cleavage rate, high-quality embryo rate, and live birth rate, while lower miscarriage rate （all P<0. 05). Compared with the group B, group C had lower cleavage rate, highquality embryo rate, and live birth rate, but higher miscarriage rate （all P<0. 05). Conclusions Serum with 10 mIU/mL ≤ LH<20 mIU/mL on the day of antagonist addition resulted in better ovulation in promoting effects and better pregnancy outcomes in IVF-ET on infertile patients. [ABSTRACT FROM AUTHOR]

Objective To know the mask use of hospital staff in Guangxi hospitals during the epidemic. Methods A selfdesigned structured questionnaire was used to survey 6 098 hospital staff from 26 medical institutions in 12 cities in Guangxi Zhuang Autonomous Region in January 2022. The survey population was divided into 3 groups: low, medium, and high risk areas. The similarities and differences in mask selection and wearing behavior among different personnel were compared. Results A total of 5 821 valid questionnaires were collected, with an effective recovery rate of 95.46%. The lower rate of correct behavior during wearing was to check the nose bridge and side of the mask for air leakage (74.0%, 4 309 persons) and to avoid touching the outside of the mask with hands while removing (69.8%, 4 063 people). Totally 2 744 people (47.1%) had their masks replaced within 4 hours; 4 007 people (68.8%) had their hands disinfected before and after wearing masks; and 2 495 people (42.9%) had their masks replaced after taking them off. The differences in mask-wearing methods, mask replacement time, correct wearing behavior, hand disinfection before and after wearing masks, and mask replacement after taking off among staff in different risk areas were statistically significant (P < 0.05), while the staff in high -risk areas had the best behavior, including use of head -mounted (adjustable) masks. About 41.9% felt that wearing a mask caused discomfort reactions, and the difference in discomfort incidence rate among staff in diferrent areas was statistically significant (P < 0.05), with the highest rate of staff in high -risk areas; 67.8% of hospital staff could correctly choose masks, with the highest rate of correct selection among staff in low-risk areas. Most surveyed respondents gave positive evaluations of their institution's measures to manage mask use. Conclusions Hospital staff had a relatively weak understanding of the protective effect of masks, and a small part of them had unsafe behavior when wearing masks. Medical institutions should strengthen supervision, management, and publicity training on correct mask -wearing behavior among hospital staff based on survey results to change unsafe mask-use behaviors among hospital staff. [ABSTRACT FROM AUTHOR]

Background Functional near-infrared spectroscopy(fNIRS) is a new generation of imaging tool that can be used to assist the diagnosis of psychiatric disorders. However, whether the patterns of prefrontal cortex activation observed by fNIRS are specific for different psychiatric disorders remains to be explored. Objective To investigate the characteristics of prefrontal cortex activation in patients with depression, anxiety disorder, bipolar disorder and schizophrenia in verbal fluency task(VFT) using fNIRS. Methods From September to December 2021, 39 patients with schizophrenia, 205 patients with depressive disorder, 212 patients with anxiety disorder and 77 patients with bipolar disorder meeting the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition(DSM-5) were recruited in the outpatient and inpatient department of West China Hospital, SichuanUniversity. fNIRS was used to monitor the prefrontal cortex hemodynamic changes of patients under VFT, and the clinical symptoms of patients were assessed by Symptom Checklist 90（SCL-90) and Hypomania Checklist-32 items（HCL-32). Differences in mean oxyhemoglobin(HbO2 ) concentration and the initial slope from 2 to 7 second during VFT were compared among patients with different diseases, and the correlation between mean HbO2 concentration/initial slope and clinical symptoms was analyzed by partial correlation analysis. Results The concentration of HbO2 in channel 4（Z=2. 828, P=0. 028) and channel 6（Z=2. 912, P=0. 022)in patients with depression were significantly higher than those in patients with schizophrenia. Patients with anxiety had significantly higher changes in mean HbO2 concentration in channel 4（Z=3. 154, P=0. 010), channel 5（Z=3. 021, P=0. 015), channel 6（Z=2. 980, P=0. 017) and of all channels(Z=2. 881, P=0. 024) than those of schizophrenia patients. There was a statistically significant difference in the initial slope of channel 3 between patients with depressive disorder and those with bipolar disorder(Z=2. 691, P=0. 039). Among patients with bipolar disorder, the anger-hostility scores of SCL-90 were negatively correlated with the mean HbO2 concentration changes in channel 4（r=-0. 505, P=0. 004), channel 6（r=-0. 390, P=0. 004), channel 15（r=-0. 546, P=0. 002), channel 16（r=-0. 550, P=0. 002) and the mean HbO2 concentration changes of all channels(r=-0. 491, P=0. 006). Conclusion Patients with schizophrenia had lower activation in frontopolar and orbitofrontal region than patients with depression and anxiety disorder, and the initial slope of the right frontopolar, inferior frontal and orbitofrontal region in patients with depression is higher than patients with bipolar disorder. In addition, patients with bipolar disorder had less activation in the frontopolar and orbitofrontal lobe, the insular cover of Broca's area and the upper outer frontal cortex, and were more irritable and hostile. ［Funded by 1·3·5 Project for Disciplines of Excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University(number, ZYJC21083). [ABSTRACT FROM AUTHOR]

BACKGROUND: At present, there are few reports on the application of compressed sensing technology in ankle MRI. OBJECTIVE: To investigate the effect of different acceleration factors in compressed sensing (CS) on image quality and scanning time of conventional 2D-MRI of the ankle joint. METHODS: Totally 24 healthy volunteers (38 ankles) underwent conventional 2D-TSE sequence scanning at 3.0T MR. Based on SENSE parallel imaging (S group) and compressed sensing technique (CS group), sequence images of T1WI-TRA (S1.3, CS1.3, CS1.9, CS2.7), PDWI-Dixon-SAG (S1.8, CS1.8, CS2.6, CS3.2) and PDWI-SPAIR-COR (S1.3, CS1.3, CS1.6, CS2.0) were obtained separately. Other scan parameters of each sequence remained consistent. The tendon, cartilage, ligament and muscle structures of the ankle joint images were subjectively scored by 5 points. The standard deviation of background noise and signal intensity of bone, cartilage, ligament, tendon, muscle, effusion and fat structures were measured, and the signal-to-noise ratio and contrast-to-noise ratio were calculated. The subjective score and objective evaluation of different acceleration factor images were statistically analyzed. SENSE group was used as the standard reference for the image quality of each sequence. RESULTS AND CONCLUSION: (1) When acceleration factor was the same, there were no statistically significant differences in subjective score, signal-to-noise ratio and contrast-to-noise ratio between the S group and the CS group (P > 0.05). (2) The acceleration factor of CS (TRA), CS (SAG) and CS (COR) sequences at CS1.9, CS2.6 and CS1.6 showed no significant difference in the image quality of cartilage, tendon, ligament and other main observed structures of the ankle joint (P > 0.05), and the scanning time was 1 minute and 32 seconds, 1 minute and 42 seconds, 1 minute and 48 seconds, respectively. When the acceleration factor of CS (TRA), CS (SAG) and CS (COR) sequences increased to CS2.7, CS3.2 and CS2.0, respectively, the subjective scores of all anatomical structures were still greater than 3, but signal-to-noise ratio and contrast-to-noise ratio of each sequence decreased significantly (P < 0.05). (3) These findings confirm that when acceleration factor is the same, compared with CS group, the image quality obtained by CS group is generally higher than that of S group. When acceleration factor increases, the scanning time of CS sequence decreases gradually, and the image quality also decreases. On a 3.0T MR, CS technology recommended CS1.9, CS2.6, and CS1.6 accelerators for conventional 2D sequences T1WI-TRA, PDWI-Dixon-SAG, and PDWI-SPAIR-COR, respectively, reducing the overall time by about 27% (1 minute and 53 seconds). [ABSTRACT FROM AUTHOR]

Objective To select the best amplification temperature and time for detection of Klebsiella pneumoniae by multiple cross displacement amplification (MCDA) combined with nanoparticles-based lateral flow biosensor (LFB), and to evaluate the effect of MCDA-LFB method for detection of Klebsiella pneumoniae. Methods According to the nu‐ cleotide sequence of the specific conserved gene rcsA of Klebsiella pneumoniae, a set of specific MCDA primers were de‐ signed using Primer Premier Version 5. 0 software, in which the crossover primer CP1 and the amplification primer C1 were labeled with fluorescein isothiocyanate (FITC) and digoxin (Dig), respectively, to establish 25 µL MCDA reaction system. The temperature increased by 60 ℃, 61 ℃, 62 ℃, 63 ℃, 64 ℃, 65 ℃, 66 ℃ and 67 ℃, each amplification for 1 h, respectively, and then the reaction was terminated after heating at 85 ℃ for 5 minutes. The DNA concentration curve was observed by real-time turbidimeter, and the MCDA amplification reaction kinetics diagram was drawn to determine the optimal amplification temperature. Under the selected optimum amplification temperature, MCDA of 10 ng/µL, 100 pg/µL, 10 pg/µL, 1 pg/µL, 100 fg/µL, 10 fg/µL, and 1 fg/µL of Klebsiella pneumoniae DNA was amplified at four time points of 10, 20, 30 and 40 min, and LFB was used for detection. The best amplification time was determined according to the LFB detection results. Thirty-six strains of Klebsiella pneumoniae and 18 strains of non-Klebsiella pneu‐ moniae were detected by MCDA-LFB method, 42 sputum samples from patients with respiratory tract infection and 3 healthy control sputum samples were detected by clinical isolation and culture method and MCDA-LFB method, and the sensitivity and specificity of MCDA-LFB method in detecting Klebsiella pneumoniae were observed. We diluted the genom‐ ic DNA of Klebsiella pneumoniae ATCC700603 standard strain to 10 ng/µL, 100 pg/µL, 10 pg/µL, 1 pg/µL, 100 fg/µL, 10 fg/µL, and 1 fg/µL, respectively, and used MCDA-LFB method to determine the lower limit of detection based on whether the result was positive. Results The optimal amplification temperature and time for detection of Klebsi‐ ella pneumoniae by MCDA-LFB were 63 ℃ and 30 min. The sensitivity and specificity of MCDA-LFB method for detecting Klebsiella pneumoniae were 100%. The lower limit of detection of Klebsiella pneumoniae by MCDA-LFB was 100 fg/µL. Conclusions The optimal amplification temperature and time for detection of Klebsiella pneumoniae by MCDA-LFB are 63 ℃ and 30 min. The method of detecting Klebsiella pneumoniae by MCDA-LFB is simple, rapid, specific and sensitive, and can be used for early screening of Klebsiella pneumoniae in clinical respiratory tract samples. [ABSTRACT FROM AUTHOR]

Objective: To observe the effect of dexmedetomidine combined with fentanyl on cellular immune function and cardioprotective effect in patients undergoing heart valve replacement. Methods: 97 patients with heart valve replacement under cardiopulmonary bypass (CPB） received in our hospital from April 2019 to June 2021 were included. According to the envelope lottery method,the patients were divided into control group (fentanyl, 48 cases） and observation group (dexmedetomidine combined with fentanyl, 49cases). The hemodynamic indexes [mean arterial pressure (MAP), heart rate (HR）], myocardial injury indexes [troponin (cTnI), creatine kinase isoenzyme (CK-MB), heart fatty acid binding protein (HFABP）], brain injury indexes [neuron specific enolase (NSE), S-100β],cellular immune function, analgesia situation and incidence of adverse reactions of the two groups were compared. Results: The HR and MAP in the observation group were lower than those in the control group at 10 min (T2） after the beginning of CPB, but higher than those in the control group at the end of CPB (T3） and the end of operation (T4) (P＜0.05). Visual analogue scale (VAS） scores in the two groups increased and then decreased before operation (T1), 24 h after operation and 48 h after operation (P＜0.05), and VAS scores in the observation group were lower than those in the control group at 24 h after operation and 48 h after operation (P＜0.05). 48 h after operation,CD4+and CD4+/CD8+in the observation group were higher than those in the control group, while CD8+was lower than that in the control group (P＜0.05). The cTnI, CK-MB and HFABP in the observation group at 48 h after operation were lower than those in the control group (P＜0.05). NSE and S100B in the observation group were lower than those in the control group at 48 h after operation (P＜0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P＜0.05). Conclusion: Dexmedetomidine combined with fentanyl anesthesia scheme for patients undergoing cardiac valve replacement can help relieve pain, stabilize hemodynamics, reduce immune suppression, and also play a protective effect on the heart and brain, reducing the incidence of adverse reactions,which is a reliable anesthesia program. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of sevoflurane inhalation anesthesia with different concentrations on awakening quality, cardiorenal function and cognitive function in patients undergoing off-pump coronary artery bypass grafting (OPCABG). Methods: 93 patients with OPCABG who were treated in our hospital from May 2018 to March 2021 were selected, and they were randomly divided into group A (sufentanil, propofol, 31 cases) and group B (sufentanil, propofol, 0.5MAC sevoflurane, 31 cases) and group C (sufentanil, propofol, 1.0MAC sevoflurane, 31 cases). The hemodynamics [heart rate (HR) and mean arterial pressure (MAP)], waking quality, cardiorenal function [cardiac troponin I (cTnI), creatine kinase (CK-MB) / creatinine (Scr), urea nitrogen (BUN)] and cognitive function [mini-mental state examination (MMSE) and Montreal cognitive function assessment scale (MoCA) score] in three groups of patients were observed, and the occurrence of adverse reactions in the three groups were recorded. Methods: The HR increased and then decreased, the MAP decreased and then increased in the three groups from immediately after operation (T1) to 24 h after operation (T3) (P<0.05). Results: The HR in group B at T1 and 6h after operation (T2) werer lower than that in group A and group C, and the MAP was higher than that in group A and group C (P<0.05). There was no significant difference in HR and MAP between group A and group C at T1 and T2 (P>0.05). There were no significant differences in the incidence of agitation during awakening among the three groups (P>0.05). The postoperative awakening time in group B was shorter than that in group A and group C (P<0.05). There was no significant difference in postoperative awakening time between group A and group C (P>0.05). The levels of cTnI, CK-MB, Scr and BUN in the three groups were higher than those before anesthesia (T0) (P>0.05). The cTnI, CK-MB, Scr and BUN levels in group B at T3 were less than those in group A and group C (P<0.05). MMSE and MoCA scores in group B at the 3rd day after operation were higher than those in group A and group C (P<0.05). There were no differences in the incidence of adverse reactions among the three groups (P>0.05). Conclusion: In patients with OPCABG, sevoflurane inhalation anesthesia combined with sufentanil and propofol anesthesia can better stabilize hemodynamics, reduce the impact on cardiorenal function and cognitive function, and improve the awakening quality, and sevoflurane at 0.5 MAC concentration has the best comprehensive effect. [ABSTRACT FROM AUTHOR]

Objective To estimate the correlation between head injury and risk of Alzheimer's disease (AD) by using meta-analysis, and to provide scientific basis for the prevention decision of AD. Methods The relevant cohort studies on the correlation between head injury and risk of AD were searched by computer in the Cochrane Library, PubMed, Medline, Embase, China National Knowledge Infrastructure databases. The search period was from January 1990 to December 2021. According to the inclusion criteria, literatures were screened and relevant data were extracted. STATA software was used to check the heterogeneity of the results and perform the meta-analysis. Results A total of 17 studies were included in the study, with a total of 5 176 850 subjects. The results of heterogeneity test showed that there was heterogeneity among the results (12=48. 3 %,P =0. 014), so the random effect model was adopted to combine effect size. The combined results showed that subjects with head injury had significant higher incidence of AD than those without head in-jury (RR =1. 12, 95 %CI :1. 03 —1. 21). According to the severity of head injury, subgroup analysis showed that the relative risk of AD in patients with moderate and severe head injury was 1.30 (95 %CI :1. 01-1. 59) [ABSTRACT FROM AUTHOR]

Objective: To compare the efficacy of endoscopic Soave radical operation and open modified Soave surgery in the treatment of children with long segment Hirschsprung's disease (HD), and to observe the effects of the two methods on stress response and defecation control function. Methods: 88 children with long segment HD who were treated in our hospital from April 2017 to September 2020 were selected, and they were divided into laparotomy group and minimally invasive group according to different surgical methods. The number of cases were 43 and 45 respectively. The perioperative indexes, stress response indexes, defecation control function and complications were compared between the two groups. Results: The intraoperative blood loss in the minimally invasive group was less than that in the laparotomy group, and the operation time, gastrointestinal function recovery time, fasting time and hospitalization time were shorter than those in the laparotomy group(P<0.05). There was no significant difference in the length of intestinal resection between the two groups (P>0.05). 1 d after operation, the heart rate (HR) and mean arterial pressure (MAP) in the two groups were higher than those before operation, and the blood oxygen saturation (SpO2) was lower than those before operation, but the HR and MAP of the minimally invasive group were lower than those of the laparotomy group, and SpO2 was higher than those of the laparotomy group (P<0.05). The stool characteristics, defecation times, fecal contamination, the need treatment (enema, medicine, diaper) score and the total score of Heikkinen in the two groups at 1 years after operation were higher than those before operation, and the minimally invasive group was higher than the laparotomy group(P<0.05). The total incidence of short-term complications and long-term complications in the minimally invasive group were lower than those in the laparotomy group (P<0.05). Conclusion: Compared with open modified Soave surgery, the treatment of long segment children with HD with endoscopic Soave radical operation can shorten the operation time, fasting time, hospitalization time, gastrointestinal function recovery time, reduce the operation trauma, reduce the body stress response, improve the defecation control function of children, and reduce the incidence of complications, and the effect is good. [ABSTRACT FROM AUTHOR]

The peanut skin dye was extracted by 60% ethanol, and its dyeing performance to linen fabric was studied ・ Direct dyeing, iron pre-mordant dyeing and aluminum pre-mordant dyeing were used to discuss the influence of dyeing temperature and dye amount on the dyeing performance of linen fabrics・ By testing the K/S and £, a, and b of the dyed fabric, the best dyeing temperature is： 120 °C for direct dyeing; 1 10 °C for Fe2+ pre・moniant; 120 °C for Al3 + pre-mordant. Peanut skin dye shows great potential for dyeing linen fabrics and the K/S value can reach above 6・ The color of fabrics dyed by mordant dyeing are quite different. Under the same dyeing conditions, the fabric K/S is the largest after Fe2+ pre-mordant dyeing・ The color fastness and UV resistance of the linen fabric under the best dyeing conditions were measured・ The color fastness of Al3 + pre-mordant dyeing can reach above level 4, and the UV resistance of Fe2+ pre-mordant dyeing is 11.8 times that of the original fabric・ After dyeing, the fluorescence performance of the dyed fabrics is obviously improved, and the fabric using direct dyeing is the best. [ABSTRACT FROM AUTHOR]

Objective A questionnaire survey was conducted among 2019 graduate students in Liaoning University of Traditional Chinese Medicine,to understand the mental health of the new graduate students,and to provide a basis for establishing a mental health education model suitable for graduate students in traditional Chinese medicine universities.Methods A cluster sampling method was adopted to select 500 newly enrolled graduate students of the university.Symptom Checklist 90 (SCL-90) was used in the mental health study,and SPSS 19.0 software was used for statistical analysis.Results The detection rate of mental health problems among the new graduate students was 19.86%,among which compulsion,sensitive interpersonal relationship and depression were the three major mental health problems.The average scores of obsessive-compulsive disorder, phobia and psychosis were higher than the national norm,and the difference was statistically significant (P <0.05).Except for depression and obsessive-compulsive disorder,the total scores and average scores of all factors were higher in boys than in girls,and the differences of interpersonal relationship and psychosis factors were statistically significant in gender (P <0.05).Conclusion The overall mental health status of the newly enrolled master's students in traditional Chinese medicine colleges is relatively lower than the national level of adults,and male students are more likely to have psychological problems than female students.Therefore, comprehensive mental health intervention should be conducted for this group as soon as possible. [ABSTRACT FROM AUTHOR]

Azoxystrobin is an important fungicide to control soybean rust. It is an urgent task to clarify the residue characteristic of azoxystrobin in soybean. In this study, ultra performance liquid chromatography tandem mass spectrometry was used to establish a method for the determination of azoxystrobin residues in stems, leaves, pods and soil in soybean planting system. The limit of quantification (LOQ) was 0.005 mg/kg. The results of field experiments in Anhui, Shandong, and Jilin showed that azoxystrobin 250 g/L SC was mainly deposited in soybean leaves after application and the deposition concentration decreased gradually from north to south. The degradation rates were faster in the upper stems and leaves, and there was no significant difference between regions. The relationship between the control effect of azoxystrobin on soybean rust was compared under different doses, and the residues were provided. The minimum effective dose of azoxystrobin was 225 g a.i./hm² . The research results of this paper are of great significance to guide the scientific application of azoxystrobin in soybean production and the practice of pesticide reduction on soybean. [ABSTRACT FROM AUTHOR]

Objective To analyze the screening results of congenital hypothyroidism(CH) in 710603 neonates in Chengdu and the treatment of confirmed cases, and to determine the influencing factors for their intellectual development.Methods The concentration of thyroid stimulating hormone(TSH) in the heel dried blood filter paper of 710 603 neonates was determined by time-resolved immunofluorescence. Neonates with positive results were recalled for reexamination of venous blood TSH, free triiodothyronine(FT3) and free thyroxine(FT4) to confirm the diagnosis. A total of 215 children were treated with levothyroxine replacement tablets. Patients were followed up regularly for height and body mass, meanwhile their intelligence was measured by Gesell Developmental Schedules(GESELL). Univariate analysis and multivariate Logistic regression analysis were used to analyze the influencing factors for CH children′s intellectual development.Results Among 710 603 neonates, 4 234(0.59%) were positive at initial screening, 4 035 cases(95.30%) were recalled, and 253 cases(0.03%) were diagnosed with CH. The 215 patients were followed up, of who 205(95.35%) began treatment within 3 months of age. FT4 in 174 cases(80.93%) returned to normal within 14 days, and TSH in 130 cases(60.47%) returned to normal within 14 d-1 month. The height of 170 cases(79.10%) and body mass of 186 cases(86.52%) reached the normal range of children at their age. Compared with children at the same age, the differences were not statistically significant(both P>0.05). The GESELL DQ of 207(98.09%) CH children had an average score of >70, and there was no statistical difference compared with that in 209 children of the normal group(99.52%)(P>0.05). The average DQ score of 140(66.67%) CH children was >85, which was statistically different from that of 165 cases(78.57%) in the normal group(P<0.05). The factors associated with CH children′s intellectual development were thyroid development, father′s educational background and treatment compliance and FT4 level( all P<0.05).Conclusions From 2016 to 2018, a total of 710 603 newborns were screened, of who 4 234 were positive for CH at the initial screening and 253 were confirmed with CH. After standardized treatment and management, the physical and mental development of children with CH basically reached the level of normal children. Thyroid color doppler ultrasonography, father′s educational background and treatment compliance and FT4 level were influencing factors for intellectual development of CH children. [ABSTRACT FROM AUTHOR]

Resin anchor material has been widely used in coal roadway and structural reinforcement. However, its pyrolysis characteristics at high temperature directly affect the mechanical properties of the material. μCT225kVFCB microscopy CT scans, SEM and the experiments of high temperature mechanical properties are used to analyze the evolution of pore structure and mechanical properties of unsaturated polyester resin anchoring material in the heating process (20-600 ℃). ① CT analysis shows that: the anchoring material's average gray at room temperature is 5.68; when the temperature ranges 350-500 ℃, the average gray shows an attenuation of 20.7%; the number of the pore group increases 47.5% and the size of the pore group increases 201.5%; the threshold range of organics attenuation coefficient is 0.016 3-0.037 3, during which the organic pyrolysis directly leads to an increase of the number of inner pore. ② SEM experimental observation shows that anchorage materials becomes dense between 20 ℃ to 200 ℃, and the carbonization of organic resin gel decomposition intensifies above 350 ℃, and the anchoring material become loose. ③ High temperature mechanical experiments show that the anchoring material strength reaches a peak at 200 ℃, which shows an increase of 32% compared with room temperature; the strength attenuation intensifies above 350 ℃, and at 600 ℃ the intensity attenuation is 98% compared to the room temperature. [ABSTRACT FROM AUTHOR]