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Background. Since the beginning of the 21st century, the world system of financial, economic and economic relations has been objectively evolving towards the formation of a post-industrial integral cyber-formation production method. This serves as a basis for talking about the onset of the era of the eponymous Integral Cyber Formation Society. The complexity of the tasks to be solved by the state and society in the course of the upcoming changes requires new approaches to organizing industry, including the use of cyber-social industrial ecosystems and mechanisms for sustainable ESGC development. The purpose of the study is to develop in the system paradigm the conceptual foundations of the mechanism of sustainable ESGC-development of the cluster-type cybersocial industrial ecosystem, as well as the justification of the need for multidimensional system modeling of this mechanism for the design of its relevant digital image. Materials and methods. The study was conducted in a system paradigm based on system theory and a system approach. To study the causes of historical evolutionary changes in economic and economic mechanisms, general scientific methods of analysis and synthesis, and system-organizational analysis tools were used. During the analysis of the actual material and to present the results, the method of structural and logical modeling and visualization of the conceptual foundations of economic and economic systems was used. Results. The main results are: a model of the organizational mechanism of the cybersocial industrial cluster, which determines the conceptual essence of the multidimensional system modeling of the mechanism of sustainable ESGC-development of the cybersocial industrial ecosystem of the cluster type; the concept of a new, engineering approach to the design and modeling of cluster-type cybersocial industrial ecosystems based on the theoretical and methodological basis of the system paradigm. Conclusions. The proposed conceptual foundations of multidimensional system modeling of the mechanism of sustainable ESGC-development of a cluster-type cybersocial industrial ecosystem will contribute to the development of the digital industry economy and increase its efficiency.

Based on the selected key indicators in the innovation sphere, an integral rating assessment of the level of innovative development (IRR) of the Arctic Zone of the Russian Federation for the period 2015–2019 was carried out and their innovative profiles were constructed, allowing to identify the strengths and weaknesses of the innovative potential of the subjects. On the basis of comparative ratings, the sufficiency of using the number of indicators for calculations and analysis of the obtained research results is justified. The rating assessment showed the leading position of the Krasnoyarsk Territory, the outsiders of the ranking include the Chukotka and Nenets Autonomous Okrugs. The authors propose a method for determining the level of sustainability of the IRR, which is calculated according to the consolidated integral index of innovative development of the region. The proposed methodological approach is based on the use of the coefficient of variation, well-known in the field of probability theory and statistics, and can be used to assess the innovation sustainability not only of regions, but also for other sectors of the economy and social sphere with corresponding changes in the system of indicators reflecting their production and economic activities. On the basis of input and output parameters, a rating of the effectiveness of innovative activity of the regions is compiled and the possibility of predictive assessments of its level for the future is shown. It is noted that in addition to the regional authorities, the results of the study can be used by various economic and social actors to monitor and forecast innovative development, as well as to adjust the existing regulatory documents in the field of innovation policy.

The incidence of Ixodes tick-borne borreliosis (ITBB) at the Island Russky (Primorsk Territory) is higher than at the mainland. There is a bidominant structure of the tick population with mass occurrence of Ixodes persulcatus and I. pavlovskyi at the island. Due to the higher infectivity and aggressiveness of I. persulcatus, it is suggested that it plays a key role in high activity of the ITBB focus at the island.The aim of the study: to characterize the role of I. pavlovskyi in the borreliosis epizootic process based on the study of the structure of the borrelia genotype complex isolated from Ixodes ticks at the Island Russky.Materials and methods. The ticks were collected from vegetation at three sites. Ixodide species were determined morphologically and using PCR for mitochondrial gene cox1 and nuclear multicopy locus ITS2. Infection of 233 ticks was analyzed with the species identification confirmed by all methods. Borrelia genospecies were determined by multiplex two-round PCR with the primers specific to the gene fragments 5S and 23S rRNA of Borrelia burgdorferi sensu lato complex.Results and discussion. Coexistence of I. persulcatus and I. pavlovskyi at the island was confirmed, with different ratios in space and a gradual increase in the proportion of the latter species. The circulation of three etiological agents of ITBB: Borrelia garinii (predominantly in I. pavlovskyi), B. bavariensis and B. afzelii (in I. persulcatus) was identified. Thus, an active natural focus of ITBB has formed at the island, probably including two uninsulated chains of borrelia circulation. One chain combines I. persulcatus and small and large mammals as the tick feeders. The second – I. pavlovskyi that can feed on mammals and birds. Due to the spatial variability of the ixodide population structure at different sections of the island, the ratio of the circulating borrelia species can change, and this species becomes the main vector of the pathogenic agents in areas of I. pavlovskyi absolute dominance.

Improving the energy density of Li-ion batteries is critical to meet the requirements of electric vehicles and energy storage systems. In this work, LiFePO4 active material was combined with single-walled carbon nanotubes as the conductive additive to develop high-energy-density cathodes for rechargeable Li-ion batteries. The effect of the morphology of the active material particles on the cathodes’ electrochemical characteristics was investigated. Although providing higher packing density of electrodes, spherical LiFePO4 microparticles had poorer contact with an aluminum current collector and showed lower rate capability than plate-shaped LiFePO4 nanoparticles. A carbon-coated current collector helped enhance the interfacial contact with spherical LiFePO4 particles and was instrumental in combining high electrode packing density (1.8 g cm−3) with excellent rate capability (100 mAh g−1 at 10C). The weight percentages of carbon nanotubes and polyvinylidene fluoride binder in the electrodes were optimized for electrical conductivity, rate capability, adhesion strength, and cyclic stability. The electrodes that were formulated with 0.25 wt.% of carbon nanotubes and 1.75 wt.% of the binder demonstrated the best overall performance. The optimized electrode composition was used to formulate thick free-standing electrodes with high energy and power densities, achieving the areal capacity of 5.9 mAh cm−2 at 1C rate.

Virus genomics as a separate branch of biology has emerged relatively recently [...]

“Green” thermally stable hardener was synthesized from a PET waste. The rigid molecular linear structure of the new hardener suggests that it will provide the polymer matrix with the necessary physical and mechanical characteristics. It also allows the expectation that cured matrix based on this hardener can provide increased toughness. New hardener was used as a curing agent for three epoxy resins—tetraglycidyl methylenedianiline (TGDMA, 111–117 EEW), diglycidylether of bisphenol A (DGEBA, 170-192 EEW) and solid epoxy resin (SER)—with a medium molecular weight (860–930 EEW) based on DGEBA. The mixtures were found to have the highest Tg for the DGEBA resin, and high of that for TGDMA and SER. According to the DMA analysis for two cured matrices, the hardener proved to be no worse than the standard ones, and made it possible to obtain cured matrices with excellent mechanical properties, which allows us to hope for further application of new hardener cured epoxy matrices in appropriate composite materials at high temperatures.

A novel polyaniline-modified CNT and graphene-based nanocomposite (2.32–7.34 nm) was prepared and characterized by spectroscopic methods. The specific surface area was 176 m2/g with 0.232 cm3/g as the specific pore volume. The nanocomposite was used to remove zinc and lead metal ions from water; showing a high removal capacity of 346 and 581 mg/g at pH 6.5. The data followed pseudo-second-order, intraparticle diffusion and Elovich models. Besides this, the experimental values obeyed Langmuir and Temkin isotherms. The results confirmed that the removal of lead and zinc ions occurred in a mixed mode, that is, diffusion absorption and ion exchange between the heterogeneous surface of the sorbent containing active adsorption centers and the solution containing metal ions. The enthalpy values were 149.9 and 158.6 J.mol−1K−1 for zinc and lead metal ions. The negative values of free energies were in the range of −4.97 to −26.3 kJ/mol. These values indicated an endothermic spontaneous removal of metal ions from water. The reported method is useful to remove the zinc and lead metal ions in any water body due to the high removal capacity of nanocomposite at natural pH of 6.5. Moreover, a low dose of 0.005 g per 30 mL made this method economical. Furthermore, a low contact time of 15 min made this method applicable to the removal of the reported metal ions from water in a short time. Briefly, the reported method is highly economical, nature-friendly and fast and can be used to remove the reported metal ions from any water resource.

Two types of poly(5-phenyl-2-norbornene) were synthesized via ring opening metathesis and addition polymerization. The polymers sulfonation reaction under homogeneous conditions resulted in ionomer with high sulfonation degree up to 79% (IEC 3.36 meq/g). The prepared ionomer was characterized by DSC, GPC, 1H NMR and FT-IR. Polymers for electromechanical applications soluble in common polar organic solvents were obtained by replacing proton of sulfonic group with imidazolium and 1-methylimidazlium. Membranes were prepared using the above-mentioned polymers and 1-ethyl-3-methylimidazolium tetrafluoroborate (EMImBF4), as well as mixtures with polyvinylidene fluoride (PVDF). Mechanical, morphological, and conductive properties of the membranes were examined by tensile testing, SEM, and impedance spectroscopy, respectively. Dry and air-stable actuators with electrodes based on SWCNT were fabricated via hot-pressing. Actuators with membranes based on methylimidazolium containing ionomers outperformed classical bucky gel actuator and demonstrated high strain (up to 1.14%) and generated stress (up to 1.21 MPa) under low voltage of 2 V.

The microporous polyvinylidene fluoride (PVDF) membranes were prepared by the solvent evaporation method using 50 wt.% of different pore-forming additives: poly(1-ethyl-3-vinylimidazolium tetrafluoroborate) (PIL-BF4), polyethylene glycol 3000 (PEG-3K) and 40000 (PEG-40K), dibutyl phthalate (DBP). The influence of used additive on morphology, porosity, degree of crystallinity, tensile properties, electrolyte uptake and ionic conductivity of the membranes were investigated. The maximum electrolyte uptake of 1-ethyl-3-methylimidazolium tetrafluoroborate (EMImBF4) was 184 wt.% for the membrane prepared with PEG-40K, however, the membrane was fragile and unsuitable for practical use. The remaining membranes showed approximately the same porosity (45‒48%) and electrolyte uptakes (169‒175%). At the same time, the membranes significantly differed in mechanical properties and ionic conductivity. The membrane prepared with PIL-BF4, unlike others, has a sponge-like structure and demonstrated high mechanical properties, namely tensile strength is 17.7 MPa and fracture strain is 132.5%. Bucky gel actuators were fabricated using membranes prepared with different additives. The blocking force of the actuators based on membranes with different additives decreased in the sequence of PIL-BF4, DBP and PEG. The actuator based on the membrane prepared with PIL-BF4 demonstrates a blocking force of 5.7 mN and a deformation of 1.35 % at 3 V DC.

Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete genomes have been sequenced. Questions about the orthopoxvirus mutation rate and the emergence of new threats to humankind as a result of the evolution of circulating orthopoxviruses remain open. Based on contemporary data on ancient VARV DNA and DNA of new orthopoxvirus species, an analysis of the molecular evolution of orthopoxviruses was carried out and the timescale of their emergence was estimated. It was calculated that the orthopoxviruses of the Old and New Worlds separated approximately 40,000 years ago; the recently discovered Akhmeta virus and Alaskapox virus separated from other orthopoxviruses approximately 10,000–20,000 years ago; the rest of modern orthopoxvirus species originated from 1700 to 6000 years ago, with the exception of VARV, which emerged in approximately 300 AD. Later, there was a separation of genetic variants of some orthopoxvirus species, so the monkeypox virus West African subtype originated approximately 600 years ago, and the VARV minor alastrim subtype emerged approximately 300 years ago.

Hydrolysis data for Bis(3-(3,4-dicyanophenoxy)phenyl) phenyl phosphate and Bis(3-(3,4-dicyanophenoxy)phenyl) phenylphosphonate under pH 4, 7 and 10 are presented. Conversion/time plots collected by HPLC analysis, typical chromatograms and NMR spectra of the reactions products are given. Pseudo-first order rate constants are determined for both substrates at 25, 50 and 80 °C. Activation parameters were calculated from Arrhenius equation. Keywords: Hydrolysis, Phthalonitrile, Phosphoric ester, Phosphonic ester, Rate constant, Activation energy

Were marked 3 groups of patients with distant damages of spine: with develope of it at early time after vertebro-spinal cord trauma, posttraumatic distant myelopathy and posttraumatic syringogydromyelia. Develope of distant damage was in 54 patients and it was by high powerfulls traumatic action, ft connected to a hard prime damage of spinal cord (79.6% had a completely disturbance of spine cord conduction). Periods of improvement conductions changed for the worse. Confirmation of defeation and level of disturbance of spine cord conduction were done by MRI and different methods of electrophysiology. Medical support and surgical operations (decompressive and bypass operations) guarantee the positive neurological results gettin almost patients.

The question of the origin of smallpox, one of the major menaces to humankind, is a constant concern for the scientific community. Smallpox is caused by the agent referred to as the variola virus (VARV), which belongs to the genus Orthopoxvirus. In the last century, smallpox was declared eradicated from the human community; however, the mechanisms responsible for the emergence of new dangerous pathogens have yet to be unraveled. Evolutionary analyses of the molecular biological genomic data of various orthopoxviruses, involving a wide range of epidemiological and historical information about smallpox, have made it possible to date the emergence of VARV. Comparisons of the VARV genome to the genomes of the most closely related orthopoxviruses and the examination of the distribution their natural hosts’ ranges suggest that VARV emerged 3000 to 4000 years ago in the east of the African continent. The VARV evolution rate has been estimated to be approximately 2 × 10−6 substitutions/site/year for the central conserved genomic region and 4 × 10−6 substitutions/site/year for the synonymous substitutions in the genome. Presumably, the introduction of camels to Africa and the concurrent changes to the climate were the particular factors that triggered the divergent evolution of a cowpox-like ancestral virus and thereby led to the emergence of VARV.