Introduction We looked at age, sex, haemoglobin, operation methods, operation time, and amount of transfusion during operation, postoperative hospital stay, postoperative complications, positive proximal margin, tumour location, tumour size, differentiation, depth of tumour invasion, lymph nodes, and lymphatic metastasis rate. The frequency of positive lymph nodes is equal to the number of metastatic lymph nodes divided by the total number of lymph nodes removed. The purpose of this research was to discover a link between clinical and pathological characteristics in stomach cancer in Odisha, India. Methods: A one-year retrospective research was conducted at the Department of General Surgery, SCB Medical college and hospital, cuttack. Results: Of the 80 patients, 50 (62.5%) were male and 30 (37.5%) were female; 50 (62.5%) had distal gastrectomy, 5 (6.25%) had proximal gastrectomy through belly and 15 (18.75%) had proximal gastrectomy via thorax, and 10 (12.5%) had complete gastrectomy. Distal and complete gastrectomy exhibited greater lymph node clearances than the other operating techniques. Postoperative problems occurred in 8 patients (10%), including stomach retention (20%), anastomotic leakage (10.5%), incision infection (9.25%), wound disruption (5.25%), and thoracic cavity effusion (5.25%). The complication was more prevalent in individuals undergoing proximal gastrectomy through abdomen (30%). Overall, the mortality rate was 1.25% (1/80). The diameter of the neoplasm was linked to the depth of infiltration and the rate of lymphatic metastasis, although haemoglobin was not. 12 (15%) of the 80 patients had early gastric cancer (EGC) with lymph node metastases. These patients had 4%-5% fewer positive lymph nodes than advanced gastric cancer patients (Table 2). In a linear regression analysis, the tumor's age and diameter were adversely linked with preoperative haemoglobin (P0.001). The tumor's diameter associated positively with age and the number of positive lymph nodes (P0.01). Patients with poorly differentiated tumours were younger than those in the other categories, who had greater tumour diameters and a higher incidence of positive lymph nodes. The depth of tumour invasion on the stomach wall was unrelated to the degree of differentiation. The tumour diameter on the corpus and fundus was greater than those on the corpus and fundus, which had a higher incidence of positive lymph nodes. Females were more likely than males to have proximal gastric cancer, poor differentiation, and a frequency of >36% positive lymph nodes. Conclusion: This retrospective investigation found that clinic-pathological characteristics of gastric cancer differed by gender, location, and tumour diameter. [ABSTRACT FROM AUTHOR]