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OBJETIVO: Traçar o perfil do uso de álcool e tabaco entre universitários do curso de graduação em Psicologia do Centro de Ciências Humanas e Naturais da Universidade Federal do Espírito Santo. MÉTODOS: Trata-se de um estudo de corte transversal, com abordagem quantitativa. A população estudada foi de alunos matriculados no referido curso no segundo semestre do ano de 2010, constituindo uma amostra de 221 estudantes. O questionário utilizado foi o mesmo utilizado no I Levantamento Nacional entre Universitários, proposto pela Secretaria Nacional de Políticas sobre Drogas. RESULTADOS: A maioria dos estudantes era solteira (90,1%), do sexo feminino (81%), estava na faixa etária de 18 a 24 anos (81%), era da raça/cor caucasoide/branca (57,5%) e 55% referiram pertencer às classes econômicas B1 e B2. Encontrou-se maior prevalência de álcool (85,07%) e tabaco (33,07%) na frequência uso na vida, sendo o uso de álcool maior que na população geral. As substâncias associadas ao uso de álcool na vida foram a maconha (p-valor = 0,007), os tranquilizantes (p = 0,011) e os anfetamínicos (p = 0,045). Já para o uso de tabaco na vida, as substâncias mais associadas foram a maconha (p = 0,0001), os inalantes (p = 0,0001), os alucinógenos (p = 0,0001) e os anfetamínicos (p = 0,001). CONCLUSÃO: É necessária maior abordagem nos currículos de graduação, especialmente da Psicologia, sobre o consumo de substâncias psicoativas e seus impactos para o indivíduo, a família e a sociedade, bem como a criação de programas preventivos específicos para estudantes universitários.OBJECTIVE: Profiling the use of alcohol and tobacco among the undergraduate students of Psychology at the Center for Human and Natural Sciences of Federal University of Espírito Santo. METHODS: The study population were students enrolled in the second semester of 2010 in the psychology undergraduate, comprising a sample of 221 students. The questionnaire used was the same used in the National Survey of College I, proposed by the National Drug Policy Secretariat. RESULTS: Most students were single (90.1%), female (81%) were in 18-24 years (81%), were the white/Caucasian race (57.5%) and 55% reported belonging to social classes B1 and B2. We found a higher prevalence of alcohol (85.07%) and tobacco (33.07%) in the frequency lifetime use, with alcohol consumption greater than in the general population. The substances associated with the use of alcohol in his life were marijuana (p-value = 0.007), tranquilizers (p = 0.011) and amphetamines (p = 0,045). As for tobacco use in life, the more substances were marijuana related (p = 0.0001), inhalants (p = 0.0001), hallucinogens (p = 0.0001) and amphetamines (p = 0.001). CONCLUSION: We need a better approach in undergraduate curricula, especially in psychology course, on the consumption of psychoactive substances and their impacts on the individual, family and society as well as the creation of specific prevention programs for college students.

Este é um artigo de revisão bibliográfica que versa sobre a gestão de um centro de educação infantil universitário. Alguns desafios da gestão centro de educação infantil universitário foram apontados, permeando vários aspectos, dentre os quais os servidores investidos em cargos administrativos atuando como professores de educação infantil e a importância do processo de democratização da escola, com a eleição de diretores, o que representa um avanço social em relação ao cenário de democratização vivenciado pela escola pública. O artigo apoiou-se na pesquisa teórica partindo da bibliografia voltada à área de gestão escolar e na pesquisa documental sobre o Centro de Educação Infantil universitário da Universidade Federal do Espírito Santo. A fundamentação legal será subsidiada pela análise de alguns artigos da Constituição da República Federativa do Brasil (1988), Lei de Diretrizes e Bases da Educação, Plano Nacional da Educação de 2014, resoluções e portarias, dentre outros.

Patients with physical disabilities can benefit from robotic rehabilitation since it can provide more control, accuracy and variety of training modes. This improves the efficiency of the patient’s rehabilitation. This work presents a multimodal platform for acquisition and processing of EEG and EMG signal with inertial sensors data in order to detect lower limb movement intentions. A pseudo-online technique was also developed. Experiments were conducted with 5 healthy subjects performing lower limb motor tasks and an experimental protocol is proposed. In the future, this interface will be integrated in an active knee orthosis for robotic rehabilitation. The results obtained show that the system is capable to acquire, process and classify the signals synchronously. The movement intention was evaluated taking into account EEG and EMG signal together with a OR logic, detecting \(60.0\pm 21.2\,\%\) of movement intentions. The movement anticipation achieved \(881.5\pm 136.3\) ms based on EEG signal and \(137.6\pm 77.5\) ms based on EMG signals.

This study aimed to analyze time trend of female mortality due to assault in Brazil, regions and states from 2002 to 2012. This is an ecological times series study with secondary data from women aged 20-59 years who died due to assault. Mortality rates were analyzed by simple linear regression and stratified by region, Gini Index and Human Development Index (HDI). The trend of female rate of mortality due to assault was stable in the country, with differences between states and regions. The Midwest had the highest rates and stagnation trend. There was an increased trend in the North, Northeast and South and a decreased trend in the Southeast. The states of the tertile with the highest HDI evidenced a declining trend and stabilization in the first and second tertiles. An increased mortality rate was recorded in states with greater social inequality. Notwithstanding the national stabilization behavior, results point to the need for social policies appropriate to the specificities of states and regions.

Ganoderma australe was studied to determine the composition of the cell wall, and polysaccharide fraction SK5 was obtained after freeze-thawing an aqueous 5% potassium hydroxide extraction. The monosaccharide composition of the SK5 fraction revealed by gas chromatography-mass spectrometry showed 81.3% glucose, and analyses by 13C nuclear magnetic resonance spectroscopy confirmed a β-glucan with glycosidic links of the (1→3)-β type and most likely 4-O substituted. In addition, the biological effect of the β-glucan from G. australe was evaluated via in vitro cell cultures of peritoneal macrophages isolated from Swiss mice. Biological assays were assessed for toxicity and cell activation, interleukin-6 cytokine concentrations, and the ability to stimulate phagocytic activity. There was an increase in interleukin-6 by approximately 111% with 1.0 µg/mL of polysaccharide, and phagocyte activity was increased in all concentrations examined, obtaining 52.3% with 0.25 µg/mL polysaccharide. The results indicate that a β-(1→3)-glucan isolated from G. australe can be classified as a biological response modifier.

The intensive use of antibiotics for human treatment and disease prevention in livestock and agriculture has led to the global threat of antibiotic resistance. To prevent the contamination of antibiotic residues through wastewater treatment plants, this paper assesses the feasibility of using UV-Vis spectrophotometer and low- frequency impedance analysis for detecting specific antibiotics in water. The change in the optical absorbance of the solutions was recorded with the spectrophotometer and the change in the values of capacitance was recorded using impedance analyser. In all cases these were dependent on the type of antibiotic and its concentration in water. The efficiency of the sensing methods in detecting different antibiotics at different concentrations is analyzed throughout the paper.

International audience; Humans with obesity differ in their susceptibility to developing insulin resistance and type 2 diabetes (T2D). This variation may relate to the extent of adipose tissue (AT) inflammation that develops as their obesity progresses. The state of macrophage activation has a central role in determining the degree of AT inflammation and thus its dysfunction, and these states are driven by epigenomic alterations linked to gene expression. The underlying mechanisms that regulate these alterations, however, are poorly defined. Here we demonstrate that a co-repressor complex containing G protein pathway suppressor 2 (GPS2) crucially controls the macrophage epigenome during activation by metabolic stress. The study of AT from humans with and without obesity revealed correlations between reduced GPS2 expression in macrophages, elevated systemic and AT inflammation, and diabetic status. The causality of this relationship was confirmed by using macrophage-specific Gps2-knockout (KO) mice, in which inappropriate co-repressor complex function caused enhancer activation, pro-inflammatory gene expression and hypersensitivity toward metabolic-stress signals. By contrast, transplantation of GPS2-overexpressing bone marrow into two mouse models of obesity (ob/ob and diet-induced obesity) reduced inflammation and improved insulin sensitivity. Thus, our data reveal a potentially reversible disease mechanism that links co-repressor-dependent epigenomic alterations in macrophages to AT inflammation and the development of T2D.

Ketoacidosis is a potentially life-threatening complication in patients with type 1 diabetes mellitus (T1DM), particularly children. If diabetic ketoacidosis (DKA) is diagnosed late, the child risks cerebral edema, permanent neurological damage or even death. There have been only few studies of DKA in Italy.From January-May 2014 a nation-wide observational, retrospective study of DKA at diabetes onset was done by the Pediatric Diabetology Study Group (PDSG) of the Italian Society of Pediatric Endocrinology and Diabetes (ISPED), involving 76 Italian centers. DKA was defined using ISPAD criteria; 7457 new cases of T1DM were recruited from mainland Italy and the island of Sicily and 770 from Sardinia, in the period 2004-2013. On the mainland and in Sicily, DKA at diabetes onset was about 32.9% (95% CI 31.8-34.0%), and there was 6.6% (95% CI 6.02-7.20%) of the severe form. Mild and severe DKA risk was significantly higher in children aged 0-4 years; no significant temporal trend was found in the study period. Patients living in Sardinia or having a firstdegree relative with T1DM were at significantly lower risk of DKA at diabetes onset. In the ten-year study period three children died of DKA at onset and four suffered permanent neurological lesions. From November 2011-April 2012 the PDSG conducted a retrospective study based on a sample of 2025 patients with T1DM, aged 0-18 years, involving 29 national centers for pediatric diabetes. The incidence of DKA was 2.4% (IC 95% 1.8-3.1), with children older than ten years at significantly higher risk, probably due to shortages of insulin. Multiple analysis showed a higher risk of DKA in those using a rapid-acting insulin analog and in those with high HbA1c. Young mothers and low levels of education were also associated with DKA.In conclusion, although a wide network of specialized home pediatricians and pediatric diabetes centers is spread across the country, the incidence of DKA at diabetes onset is still high. Further social and health-system efforts are needed to boost awareness of this risk and to reduce damages and costs related to the complication.

A partire dal luglio 2011 il centro storico di Napoli è stato interessato dall’istituzione di Zone a Traffico Limitato (ZTL). Sulla base di criteri di omogeneità storico-urbanistica, è stata perimetrata un’area di studio più ampia di quella strettamente interessata dalle ZTL, ma che comprende parte del territorio comunale presumibilmente influenzato dagli effetti dei dispositivi di traffico introdotti; per tale area, relativamente al periodo 2007-2013, è stata esaminata la variazione dei valori di mercato e di locazione, con riferimento agli immobili residenziali e commerciale. In particolare, i valori immobiliari disponibili sono stati inseriti in un GIS ed è stata condotta un’analisi multivariata, individuando le correlazioni tra detti valori. Successivamente sono state dedotte delle “regole decisionali”, che sono state utilizzate all’interno di una analisi multicriterio, i cui risultati hanno consentito di proporre alcuni indirizzi progettuali di modifica degli attuali dispositivi del traffico. Parole chiave: mercato immobiliare, GIS, metodo ELECTRE, BDC. Bollettino Del Centro Calza Bini, Vol 14, N° 1 (2014): Complex Evaluations for Hybrid Landscapes

The incidence of type 1 diabetes in childhood is increasing by 3 % per year, placing growing demands on healthcare professionals and medical expenditures. Aim of this study wars to assess the organization of care to children with diabetes in Italy.During 2012 a structured questionnaire was sent to all of the members of Italian Society of Paediatric Endocrinology and Diabetology (ISPED). Questions examined organizational structure of Centers, personnel dedicated to the care of children with diabetes, number of subjects followed, local legal legislation supporting centres.A total of 68 centers taking care to 15,563 children and adolescents with diabetes under 18 years of age were identified with a prevalence of 1.4 per 1,000 people. A wide variation in the organizational background was also reported. Fourty-four centers were organized as outpatient departments, 17 as simple units, 5 as complex units and 2 as simple departmental structures. Most centers had a multidisciplinary team. Ten out of twenty Italian regions had introduced supportive regional legislation, but it was fully applied only in six of them.Great differences between regions were found in organizational structures, staffing levels and supportive legislation. The national legislation on diabetes was broadly implemented throughout the country regions. Further efforts are needed to improve standards and consistency of pediatric diabetes care in Italy.

Kabelbaserede brøndindgreb i højtemperatur brønde er en af de største udfordringer i olie- og gasindustrien i dag. De høje temperaturer nede i hullet, som kan nå op på 200 °C, reducerer levetiden for de elektriske komponenter i de kabelbaserede robot værktøjer indtil nedbrud. En mulig løsning på overophedningen af elektronikken er aktive kølesystemer, idet disse ville kunne holde de følsomme elektronikkomponenter ved tålelige temperaturer imens de opererer i varme omgivelser. Dette arbejde præsenterer design, konstruktion og test af en aktivt kølet down-hole elektroniksektion, som kan køle de kritiske elektriske komponenter til under 175 °C imens den opererer i omgivelser på 200 °C, som nede i en brønd. Efter en undersøgelse af forskellige køleteknikker og den termiske karakterisering af de elektriske komponenter der benyttes i brønden blev det besluttet at benytte termoelektriske kølere. Disse termoelektriske kølere implementerede et nyt koncept til varmestyringen i forhold til tidligere arbejder, således at det valgte design kombinerer både aktive og passive køleteknikker med det mål at opnå en effektiv varmestyrring, samtidig med at bibeholde værktøjets kompakthed og at undgå brugen af bevægelige dele. Det endelige design af prototypen som kunne holde den temperatur følsomme elektronik under 170 °C imens den opererede ved over 200 °C i mere end 200 timer blev udviklet med topologioptimering kombineret med en finite element model. Effektiv elektrisk integration af kølesystemet i down-hole værktøjet blev også studeret og et pulsbredde-modulationskredsløb blev udviklet for at tilpasse down-hole strømforsyningen til en passende spænding til den termoelektriske køler. Implementeringen af det aktive kølesystem blev understøttet af et studie af den termiske vekselvirkning imellem down-hole værktøjet og omgivelserne i brønden, hvilket var relevant for at kunne definere varmeafgivelsen. I mangel af information i den videnskabelige litteratur blev der designer og testet en down-hole sensor der kunne kvantificere varmeoverførselshastigheden imellem værktøjet og brøndboringen eksperimentelt. Konceptet blev bevist og sensoren kalibreret i en laboratorie flow løkke med god overensstemmelse imellem eksperimentelle resultater og modelforudsigelser. De gennemsnitlige og maksimale afvigelser imellem de målte og forudsagte varmeoverføringskoefficienter var på henholdsvis 3% og 10%. Wireline interventions in high temperature wells represent one of today’s biggest challenges for the oil and gas industry. The high wellbore temperatures, which can reach 200 °C, drastically reduce the life of the electronic components contained in the wireline downhole tools, which can cause the intervention to fail. Active cooling systems represent a possible solution to the electronics overheating, as they could maintain the sensitive electronics at a tolerable temperature, while operating in hotter environments. This work presents the design, construction and testing of an actively cooled downhole electronics section, which is able to cool the critical electronics below 175 °C while operating at 200 °C. After the investigation of several cooling techniques and the thermal characterization of the studied downhole electronics, thermoelectric coolers were chosen to implement a novel concept of heat management for downhole tools. The chosen design combined active and passive cooling techniques aiming at efficient thermal management, preserving the tool compactness, and avoiding the use of moving parts. Topology optimization was used, in combination with a finite element model of the system, to develop the final design of an actively cooled prototype, which was able to continuously maintain the temperature-sensitive electronics below 170 °C, while operating at 200 °C for more than 200 hours. Effective electrical integration of the cooling system in a wireline downhole tool was also studied, and a power-width-modulation circuit was developed to adapt the downhole power source to a suitable voltage for the thermoelectric cooler. The implementation of the active cooling system was supported by the study of the thermal interaction between the downhole tool and the well environment, which was relevant to define the heat rejection conditions. Given the lack of information from the scientific literature, a downhole sensor that could experimentally quantify the heat transfer rate occurring between the tool and the wellbore was designed and tested. The concept was proved and the sensor calibrated in a laboratory flow loop. Average and maximum mismatches of 3% and 10%, respectively, were found between the measured and predicted heat transfer coefficients, showing good agreement between experimental results and model forecasts.

Basis sets of valence double and quadruple zeta qualities and the Douglas-Kroll-Hess (DKH) approximation are used to estimate the impact of an all-electron basis set and scalar relativistic effects on the structure, stability, and electronic properties of small neutral copper clusters (Cun, n ≤ 8). At the Becke three-parameter for exchange and Perdew-Wang 91 for correlation (B3PW91) non-relativistic and relativistic levels of theory, the bond length, binding energy, ionization potential, electron affinity, chemical potential, chemical hardness, and electrophilicity index are calculated. The results show that the agreement with experiment improves significantly when the DKH Hamiltonian combined with an all-electron relativistic basis set is used. Polarizabilities and hyperpolarizability are also reported. At the B3PW91 level, all-electron basis sets are shown to be more reliable than effective core potential valence basis sets in the determination of the second hyperpolarizability of copper clusters.

This paper presents an environment-detection-and-mapping algorithm for autonomous driving that is provided in real time and for both rural and off-road environments. Environment-detection-and-mapping algorithms have been designed to consist of two parts: (1) lane, pedestrian-crossing, and speed-bump detection algorithms using cameras and (2) obstacle detection algorithm using LIDARs. The lane detection algorithm returns lane positions using one camera and the vision module “VisLab Embedded Lane Detector (VELD),” and the pedestrian-crossing and speed-bump detection algorithms return the position of pedestrian crossings and speed bumps. The obstacle detection algorithm organizes data from LIDARs and generates a local obstacle position map. The designed algorithms have been implemented on a passenger car using six LIDARs, three cameras, and real-time devices, including personal computers (PCs). Vehicle tests have been conducted, and test results have shown that the vehicle can reach the desired goal with the proposed algorithm.

SUMMARY Basaloid squamous cell carcinoma is a recently recognized, rare and aggressive variant of squamous cell carcinoma with a predilection to occur in base of the tongue, hypopharynx and larynx (especially the supraglottic tract). It is usually diagnosed in advanced stage, frequently with distant metastases, requiring aggressive surgical intervention. The prognosis is remarkably poor even after the association of radiotherapy or chemotherapy. Nevertheless recently it has been reported that in the early stage this neoplasm seems to have a behaviour less aggressive, similar to conventional squamous carcinoma. The therapeutic approach is not clearly defined when the neoplasm is diagnosed at an early stage. We present a case of early stage of basaloid squamous cell carcinoma of the supraglottic larynx.

Laparoscopy is a valuable approach to primary ileocecal resection for ileocolonic Crohn's disease (CD). This study aimed to evaluate the feasibility of using laparoscopy for reoperation in the case of ileocolonic CD recurrence and to determine the risk factors and consequences of conversion for these patients.From 1998 to 2008, 57 patients underwent 62 reoperations for CD recurrence. Of these 62 reoperations, 29 were laparoscopic procedures (laparoscopy group [LG]). Preoperative and intraoperative characteristics and postoperative outcome were compared with those for 33 open procedures (open group [OG]).The preoperative characteristics were similar in the two groups. The number of intraoperative intestinal injuries was higher in the LG group (n = 5) than in the OG group (n = 0) (p = 0.01). The use of a temporary stoma (7/29 vs. 6/33; nonsignificant difference [NS]) and the mean operating time (215 + or - 70 vs. 226 + or - 107 min, NS) were similar in the two groups. The postoperative mortality was nil in both groups. The overall morbidity rate was 38% (11/29) in LG and 30% (10/33) in OG (NS). Severe complications (DINDOor = 3) occurred for three of the 29 patients in LG (10%) compared with five of 33 patients in OG (15%) (NS). The median hospital stay was 9 days in both groups. The conversion rate was 31% (9/29). Univariate analysis showed that the risk factors for conversion were fistulizing disease (p = 0.02) and intraoperative intestinal injury (p0.001). The morbidity rate was not increased by the need for a conversion (7/20 for the nonconverted vs. 4/9 for the converted patients, NS).Laparoscopy for ileocolonic CD recurrence is challenging and complex. The morbidity rate was similar to that for the open approach, and the risk of small bowel injury associated with laparoscopy could possibly induce postoperative septic complications. However, the authors believe that laparoscopy can be recommended for selected patients with CD recurrence, especially patients with nonfistulizing disease.

Made available in DSpace on 2016-08-29T11:12:27Z (GMT). No. of bitstreams: 1 tese_9195_Dissertação Final - Maria José Rassele.pdf: 76947000 bytes, checksum: bf1490557a8104ff481384855019e3a0 (MD5) Previous issue date: 2015-09-01 A presente pesquisa tratou dos diversos aspectos envolvidos no desvio de função do servidor público federal, titular de cargo efetivo, em um centro de educação infantil universitário. O desvio de função no campo de pesquisa aqui tratado envolveu atividade docente sendo exercida por profissionais que não estavam formalmente investidos no cargo de professor. O estudo objetivou desvelar como se efetivou o desvio de função no centro de educação infantil da autarquia federal, pesquisar os motivos determinantes da ocorrência do desvio de função e analisar como os servidores que atuaram em desvio funcional foram psicológica e emocionalmente afetados por tal situação. A pesquisa apresenta um caráter qualitativo descritivo no qual se utilizou como instrumento de coleta de dados a entrevista semiestruturada para desvendar algumas particularidades que permeiam o tema. Pesquisou-se a trajetória histórica do centro de educação infantil que tem prestado seus serviços à comunidade há quase quarenta anos. Realizou-se pesquisa bibliográfica e empírica sobre o tema do desvio funcional. Traçou-se um recorte temporal ex post facto, visto que o problema das inconsistências funcionais dos servidores federais no setor é fato já consumado que se prolonga no tempo e espaço. Concluiu-se que o desvio de função é uma ambiguidade presente no âmbito da Administração Pública, e na instituição analisada, permeando questões relacionadas ao trabalho docente e aos impactos gerados pela prestação do serviço por servidores em desvio de função. O tema merece ser tratado com maior atenção pela Administração Pública na perspectiva de promover uma solução para as implicações que essa problemática traz para os diferentes atores nela envolvidos: a administração, o servidor, assim também o usuário do serviço.

Background Several studies show that the consumption of vegetable oils, such as soybean oil, rich in polyunsaturated fatty acids (PUFAs) has beneficial health effects by preventing or reducing the risk factors of cardiovascular diseases. While the demonstration of beneficial effects of the consumption of unsaturated fatty acids on the cardiovascular system has been proven in a macroscopic level, the molecular/cellular mechanisms responsible for this phenomenon are poorly understood. Methods In this work, a comparative proteomic approach, two-dimensional gel electrophoresis (2-DE) coupled to mass spectrometry (MALDI-TOF/TOF), was applied to investigate proteome differences in the left ventricle (LV) of rats that received 0.1 mL of soybean oil intramuscularly for 15 days (treated group - TR) and rats that had not (control group - CT). Results Soybean oil treatment improved left ventricular function, TR animals presented lower value of LVEDP and significantly changed LV proteome. The protein profile of VE revealed differences in the expression of 60 protein spots (p

Made available in DSpace on 2016-08-29T14:12:15Z (GMT). No. of bitstreams: 1 tese_7642_DISSERTAÇÃO cópia final impressão e site Ufes.pdf: 3425403 bytes, checksum: d163971835398117c597e07f6b4ea307 (MD5) Previous issue date: 2015-04-10 De 1847 a 1882, a Província do Espírito Santo passou pelo processo de formação de colônias de imigrantes (estatais ou particulares), principalmente de europeus, dentro de um amplo programa do governo imperial para importação de mão de obra para colonização territorial do País e substituição de trabalho escravo. Dentro desse contexto é que se formaram as colônias de Santa Isabel, Rio Novo e Santa Leopoldina, as três que tiveram maior desenvolvimento regional. Toda essa trajetória é relatada em documentos oficiais: relatórios de ministros do Império e de presidentes e vice-presidentes da Província que, ao longo dos anos, apresentaram informações burocráticas, mas também manifestaram opiniões, muitas e muitas vezes pejorativas, em relação aos imigrantes; opiniões essas que variaram conforme o governante e o período. É em torno dessas opiniões que se centra essa dissertação, formulada dentro da linha de pesquisa Estado e Políticas Públicas do Programa de Pós Graduação de História da Universidade Federal do Espírito Santo (PPGHIS-Ufes).

Few data exist about the characteristics and management of enteric leaks after mini-gastric bypass (MGB).We aimed to describe the incidence, presentation, and surgical management of enteric leaks in patients who underwent laparoscopic MGB for morbid obesity.Private practice.An 8-year, 9-month retrospective chart review was performed on patients who had enteric leak requiring reoperation after MGB at a single institution.Thirty-five of 2321 patients were included. Ninety-seven percent had symptoms. Arterial hypertension and heavy smoking were predicting factors of leaks occurrence post-MGB (P.01). Enteric leak was diagnosed by systematic upper gastrointestinal series in 4 pts (11.4%) and by computed tomography with oral water soluble contrast in 4 of 31 pts (13%). In the other 27 patients, diagnosis of the leak was made intraoperatively. Eleven patients (32%) had leak arising from the gastric stapler line (type 1), 4 (11%) from the gastrojejunal anastomosis (type 2), and 20 (57%) from undetermined origin. The most common presentation was intra-abdominal abscess in type 1 and leaks of undetermined origin and generalized peritonitis in type 2. One third of the patients who underwent reoperation developed well-drained chronic fistula into the irrigation-drainage system, with complete healing in all patients without any further procedure. The mean hospital stay was 19 days with no mortality reported.Enteric leak leading to intra-abdominal sepsis post-MGB is rare (1.5%) An operative aggressive management based on clinical symptoms is the treatment of choice allowing no postoperative leak-related mortality and complete healing.

Submitted by Maykon Nascimento (maykon.albani@hotmail.com) on 2015-10-27T18:09:39Z No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) O desvio de funcao no centro de educacao de uma autarquia federal.pdf: 4365003 bytes, checksum: df89aa9a4b452e4bd0c7ba77132fa5a6 (MD5) Approved for entry into archive by Elizabete Silva (elizabete.silva@ufes.br) on 2015-11-03T18:57:36Z (GMT) No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) O desvio de funcao no centro de educacao de uma autarquia federal.pdf: 4365003 bytes, checksum: df89aa9a4b452e4bd0c7ba77132fa5a6 (MD5) Made available in DSpace on 2015-11-03T18:57:36Z (GMT). No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) O desvio de funcao no centro de educacao de uma autarquia federal.pdf: 4365003 bytes, checksum: df89aa9a4b452e4bd0c7ba77132fa5a6 (MD5) Previous issue date: 2015 A presente pesquisa tratou dos diversos aspectos envolvidos no desvio de função do servidor público federal, titular de cargo efetivo, em um centro de educação infantil universitário. O desvio de função no campo de pesquisa aqui tratado envolveu atividade docente sendo exercida por profissionais que não estavam formalmente investidos no cargo de professor. O estudo objetivou desvelar como se efetivou o desvio de função no centro de educação infantil da autarquia federal, pesquisar os motivos determinantes da ocorrência do desvio de função e analisar como os servidores que atuaram em desvio funcional foram psicológica e emocionalmente afetados por tal situação. A pesquisa apresenta um caráter qualitativo descritivo no qual se utilizou como instrumento de coleta de dados a entrevista semiestruturada para desvendar algumas particularidades que permeiam o tema. Pesquisou-se a trajetória histórica do centro de educação infantil que tem prestado seus serviços à comunidade há quase quarenta anos. Realizou-se pesquisa bibliográfica e empírica sobre o tema do desvio funcional. Traçou-se um recorte temporal ex post facto, visto que o problema das inconsistências funcionais dos servidores federais no setor é fato já consumado que se prolonga no tempo e espaço. Concluiu-se que o desvio de função é uma ambiguidade presente no âmbito da Administração Pública, e na instituição analisada, permeando questões relacionadas ao trabalho docente e aos impactos gerados pela prestação do serviço por servidores em desvio de função. O tema merece ser tratado com maior atenção pela Administração Pública na perspectiva de promover uma solução para as implicações que essa problemática traz para os diferentes atores nela envolvidos: a administração, o servidor, assim também o usuário do serviço. This research dealt with the various aspects involved in improper allocation of public servants in an Early Childhood Education Center of a Federal University. The improper allocation of public servants in the research field involved the performance of teaching activities by public servants who were not formally assigned to occupy that specific position. Thus, the study aimed to clarify how the improper allocation of public servants took place at the Early Childhood Education Center of a Federal University, research the determining reasons for the improper allocation of public servants and analyze how the public servants who worked under such circumstances were psychologically and emotionally affected by the situation. The study presents a descriptive qualitative approach in which the semi-structured interview was used as an instrument for collecting data to unravel some particularities that permeate the theme. The historical path of the Early Childhood Education Center, which has provided its services for the community for almost forty years, was constructed. Bibliographical and empirical researches about improper allocation of public servants within specific public posts were conducted. A time frame using the ex post facto method was traced since the problem of improper allocation of public servants at the research field has already ended. The conclusion shows that the improper allocation of public servants reveals to be an ambiguous matter for Public Administration as well as for the institution analyzed, permeating issues related to the teaching post and to the physiological impacts caused on public servant’s performance in a job position that is considered unlawful. The subject deserves to be treated more attentively by the public authorities as to provide solution to the implications brought by this issue to the different actors involved in the situation: the public administration, the public servant, as well as the public service user.

The present study was conducted to investigate a possible correlation between plasma (PVL) and seminal viral load (SVL) on treatment-naïve HIV-1-infected patients in Vitória, ES, Brazil. We also evaluated whether the progressive immunosuppression associated with HIV disease (as evidenced by declining CD4 T cell counts) has any impact on the correlation between PVL and SVL HIV-1. Viral load on paired blood and semen samples from 56 consecutive treatment-naïve patients were evaluated and compared to CD4 cell counts. Viral load and T cell counts (cells/microl) were determined by NASBA and by flow cytometry, respectively. Overall, a strong positive correlation between PVL and SVL (rho = 0.438, p = 0.001) was observed. However, when patients were grouped according to their CD4 counts, this correlation was only significant among patients with CD4 counts200 cells/microl. Results presented here demonstrate the existence of a strong correlation between PVL and SVL on patients with CD4 cell counts200 cells/microl, suggesting that this association may correlate with disease progression.

Submitted by Maykon Nascimento (maykon.albani@hotmail.com) on 2015-03-06T19:28:59Z No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Dissertação Douglas Soprani.pdf: 12382633 bytes, checksum: 47ecc259e614e63704f16a4d7f45023c (MD5) Approved for entry into archive by Elizabete Silva (elizabete.silva@ufes.br) on 2015-03-23T18:59:35Z (GMT) No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Dissertação Douglas Soprani.pdf: 12382633 bytes, checksum: 47ecc259e614e63704f16a4d7f45023c (MD5) Made available in DSpace on 2015-03-23T18:59:35Z (GMT). No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Dissertação Douglas Soprani.pdf: 12382633 bytes, checksum: 47ecc259e614e63704f16a4d7f45023c (MD5) Previous issue date: 2015-03-06 Esta dissertação apresenta o desenvolvimento de uma plataforma multimodal de aquisição e processamento de sinais. O projeto proposto insere-se no contexto do desenvolvimento de interfaces multimodais para aplicação em dispositivos robóticos cujo propósito é a reabilitação motora adaptando o controle destes dispositivos de acordo com a intenção do usuário. A interface desenvolvida adquire, sincroniza e processa sinais eletroencefalográficos (EEG), eletromiográficos (EMG) e sinais provenientes de sensores inerciais (IMUs). A aquisição dos dados é feita em experimentos realizados com sujeitos saudáveis que executam tarefas motoras de membros inferiores. O objetivo é analisar a intenção de movimento, a ativação muscular e o início efetivo dos movimentos realizados, respectivamente, através dos sinais de EEG, EMG e IMUs. Para este fim, uma análise offline foi realizada. Nessa análise, são utilizadas técnicas de processamento dos sinais biológicos e técnicas para processar sinais provenientes de sensores inerciais. A partir destes, os ângulos da articulação do joelho também são aferidos ao longo dos movimentos. Um protocolo experimental de testes foi proposto para as tarefas realizadas. Os resultados demonstraram que o sistema proposto foi capaz de adquirir, sincronizar, processar e classificar os sinais combinadamente. Análises acerca da acurácia dos classificadores utilizados mostraram que a interface foi capaz de identificar intenção de movimento em 76, 0 ± 18, 2% dos movimentos. A maior média de tempo de antecipação ao movimento foi obtida através da análise do sinal de EEG e foi de 716, 0±546, 1 milisegundos. A partir da análise apenas do sinal de EMG, este valor foi de 88, 34 ± 67, 28 milisegundos. Os resultados das etapas de processamento dos sinais biológicos, a medição dos ângulos da articulação, bem como os valores de acurácia e tempo de antecipação ao movimento se mostraram em conformidade com a literatura atual relacionada. This master thesis presents a multimodal platform for acquisition and signal processing. The proposed interface acquires, synchronizes and processes electroencephalographic (EEG) signals, electromiographic signals (EMG) and inertial sensors (IMUs) signals. The data acquisition is done in experiments with healthy subjects performing motor tasks of lower limbs. The objective is to analyze the movement intention, the muscle activation and the movement onset. To do so, an offline analysis was performed. In the analysis are shown EEG signal processing techniques, whose aim is to identify movement intention, and EMG signal techniques aiming at identifying the initial muscle activation. Techniques for processing signals from inertial sensors whose aim is to identify movement onset and measure the knee joint angles are also shown. An experimental protocol is proposed. The platform can be used in the development of interfaces for rehabilitation robotics devices aiming at adapting their control with respect to the patient’s intention. The results obtained showed that the system is capable to acquire, process and classify the signals synchronously. The movement intention was detected in 76, 0 ± 18, 2% of the movements. The movement antecipation achieved 716, 0 ± 546, 1 ms based on EEG signal and 88, 34 ± 67, 28 ms based on EMG signals. The results of the biological signal processing, the movement antecipation times, the accuracy of classifiers and joint angles measurements were in accordance with the currently related studies.

The biosynthesis pathway of eicosanoids derived from arachidonic acid, such as prostaglandins and leukotrienes, relates to the pathophysiology of diabetes mellitus (DM). A better understanding of how lipid mediators modulate the inflammatory process may help recognize key factors underlying the progression of diabetes complications. Our review presents recent knowledge about eicosanoid synthesis and signaling in DM-related complications, and discusses eicosanoid-related target therapeutics.

Esta tesis de producción se basa en la recopilación de distintas experiencias recogidas sobre seis municipios de la provincia de Buenos Aires los cuales son Berisso, Ensenada, Punta Indio, Florencio Varela, Roque Pérez y San Miguel del Monte. Por otra parte se realizaron distintas entrevistas a funcionarios y asesores abocados a la comunicación de gobierno municipal. La investigación se realizó durante el periodo que corresponde desde septiembre de 2013 a julio de 2014 a fin de interiorizarse en las condiciones, problemáticas, alcances, limitaciones y demás características que hacen a la comunicación de gobierno en los municipios para así poder entenderla y poder concebir un material orientado a estas instituciones. Se generó un manual cuyo fin es convertirse en una herramienta comunicacional orientada a intendentes, funcionarios municipales, dirigentes políticos, militantes político/sociales, consultores y profesionales, investigadores docentes y estudiantes interesados sobre la temática., Facultad de Periodismo y Comunicación Social

A new class of polymer electrolytes, based on the interpenetrating polymer network approach, was obtained starting from functionalised macromers, of poly-ether nature, in the presence of a lithium salt (LiBF4, LiClO4, LiCF3SO3) and propylene carbonate (PC) or tetraethyleneglycol dimethylether (TGME), as plasticizers. The macromers were synthesised by living polymerisation employing a HI/I2 system as the initiator. The macromer has a polymerisable end group, which can undergo radical polymerisation, attached to a monodisperse poly-vinylether, containing suitable ethylene oxide groups for ion coordination. Monomers and macromers were characterised by FTi.r., u.v.–vis, 1H- and 13C-n.m.r. Self-consistent and easily handled membranes were obtained as thin films by a dry procedure using u.v. radiation to polymerise and crosslink the network precursors, directly on suitable substrates, in the presence of the plasticizer and the lithium salt. The electrolytic membranes were studied by complex impedance and their thermal properties determined by differential scanning calorimetry analysis. Ionic conductivities (σ) were measured for PC and TGME-based membranes at various plasticizer and salt contents as a function of T (60 to −20°C). LiClO4/PC/PE electrolytes, with 3.8% (w/w) salt and 63% PC, have the highest σ (1.15×10−3 and 3.54×10−4 S cm−1 at 20°C and −20°C, respectively). One order of magnitude lower conductivities are achieved with TGME; samples with 6% (w/w) LiClO4 and 45% (w/w) TGME exhibit σ values of 2.7×10−4 and 2.45×10−5 S cm−1 at 20°C and −20°C.